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Relationship between 24-hour activity behaviors and depression in older adults with multimorbidity using the isotemporal substitution model:A cross-sectional study
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作者 Pei-Ya Tao Ju-Feng Chen +3 位作者 Yu-Xi Chen Sunanjie Zhao Guo-Hu Han Zhuo Wang 《Nursing Communications》 2026年第5期1-9,共9页
Background:The phenomenon of multimorbidity in chronic diseases among the elderly is prevalent,and its significant association with depression poses a serious threat to the physical and mental health of older adults.C... Background:The phenomenon of multimorbidity in chronic diseases among the elderly is prevalent,and its significant association with depression poses a serious threat to the physical and mental health of older adults.Current research on the associations between 24-hour movement behaviors(including physical activity,sedentary behavior,and sleep)and depression has largely been confined to examining the effects of single behaviors,overlooking the intrinsic compositional nature and interrelationships among these behaviors.Therefore,it is necessary to investigate the integrated effects of 24-hour movement behaviors on depression in older adults with multimorbidity from a holistic,compositional perspective.Methods:From November 2024 to April 2025,a total of 226 older adult patients with multimorbidity were recruited from a tertiary hospital in Changzhou City.Data were collected using a general information questionnaire,the International Physical Activity Questionnaire–Short Form(IPAQ-SF),the Pittsburgh Sleep Quality Index(PSQI),and the Patient Health Questionnaire-9(PHQ-9).Compositional data analysis and isotemporal substitution models were employed for statistical analysis.Results:The mean daily durations of Light-Intensity Physical Activity(LPA),Moderate-to-Vigorous Physical Activity(MVPA),Sedentary Behavior(SB),and Sleep(SLP)in older adults with multimorbidity were 402.48 min,12.04 min,511.52 min,and 458.68 min,respectively.The prevalence of depressive symptoms was 37.6%.Compositional data analysis revealed that SB was positively associated with depression(βSB=1.005,P=0.006),while SLP was negatively associated with depression(βSLP=−1.736,P<0.001).No statistically significant associations were found between MVPA or LPA and depression(P>0.05).In the 10-minute isotemporal substitution model,replacing SB with any other behavioral component was associated with a decrease in depression scores.Conversely,substituting SLP with either LPA or SB resulted in an increase in depression scores,while substituting SLP with MVPA led to a decrease in depression scores.The dose-response analysis revealed that,among the isotemporal substitution effects,replacing SB with SLP and replacing SLP with MVPA were the substitution pathways associated with the most rapid decline in depression scores,representing the greatest beneficial health effects.Conclusion:The prevalence of depression is notably high among older adults with multimorbidity.Reducing daily sedentary behavior(SB),maintaining adequate sleep(SLP),and increasing moderate-to-vigorous physical activity(MVPA)can improve depressive symptoms and enhance overall health in this population. 展开更多
关键词 24-hour activity behaviors isotemporal substitution model compositional data analysis MULTIMORBIDITY DEPRESSION older adults
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Is Meeting 24-Hour Movement Guidelines Associated with Emotion Regulation among Children and Adolescents?
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作者 Shanshan Xu Liang Hu 《International Journal of Mental Health Promotion》 2025年第6期771-785,共15页
Background:The Canadian 24-h movement guidelines(24-HMG)emphasize the holistic consideration of physical activity(PA),sedentary behavior,and sleep in shaping health outcomes.This study aimed to examine the association... Background:The Canadian 24-h movement guidelines(24-HMG)emphasize the holistic consideration of physical activity(PA),sedentary behavior,and sleep in shaping health outcomes.This study aimed to examine the associations between meeting 24-HMG and emotion regulation-related indicators among children and adolescents.Methods:A total of 534 Chinese children and adolescents aged 12.94±1.10 years(49.81%males)participated in this study and completed self-report measures assessing 24-h movement behaviors,emotion regulation strategies,emotion regulation flexibility,and regulatory emotional self-efficacy.Results:Only 7.12% of theparticipants adhered to two or all three guidelines.The number of guidelines met was positively associated with the use of emotion regulation strategies,emotion regulation flexibility,and regulatory emotional self-efficacy.Compared with meeting none of the guidelines,participants whomet one ormore guidelines reported significantly better performance in these outcomes.Conclusion:Meeting 24-HMG was associated with superior emotion regulation in children and adolescents.The importance of engaging in regular PA,limiting recreational screen time,and getting enough sleep should be highlighted for fostering emotion regulation in this demographic. 展开更多
关键词 24-hour movement guidelines emotion regulation strategies emotion regulation flexibility regulatory emotional self-efficacy
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Associations between meeting 24-hour movement guidelines and quality of life among children and adolescents with autism spectrum disorder 被引量:4
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作者 Chuidan Kong Aiguo Chen +9 位作者 Sebastian Ludyga Fabian Herold Sean Healy Mengxian Zhao Alyx Taylor Notger G.Muller Arthur F.Kramer Sitong Chen Mark S.Tremblay Liye Zou 《Journal of Sport and Health Science》 SCIE CSCD 2023年第1期73-86,共14页
Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring... Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring and optimizing the health and quality of life(QoL)of children and adolescents.However,this topic has yet to be examined for children and adolescents with autism spectrum disorder(ASD)specifically.The aim of this cross-sectional observational study was to examine the associations between meeting 24-HMB guidelines and several QoLrelated indicators among a national sample of American children and adolescents with ASD.Methods:Data were taken from the 2020 U.S.National Survey of Children’s Health dataset.Participants(n=956)aged 617 years and currently diagnosed with ASD were included.The exposure of interest was adherence to the 24-HMB guidelines.Outcomes were QoL indicators,including learning interest/curiosity,repeating grades,adaptive ability,victimization by bullying,and behavioral problems.Categorical variables were described with unweighted sample counts and weighted percentages.Age,sex,race,preterm birth status,medication,behavioral treatment,household poverty level,and the educational level of the primary caregivers were included as covariates.Odds ratio(OR)and 95%confidence interval(95%CI)were used to present the strength of association between adherence to 24-HMB guidelines and QoL-related indicators.Results:Overall,452 participants(45.34%)met 1 of the 3 recommendations,216(22.65%)met 2 recommendations,whereas only 39 participants(5.04%)met all 3 recommendations.Compared with meeting none of the recommendations,meeting both sleep duration and PA recommendations(OR=3.92,95%CI:1.639.48,p<0.001)or all 3 recommendations(OR=2.11,95%CI:1.034.35,p=0.04)was associated with higher odds of showing learning interest/curiosity.Meeting both screen time and PA recommendations(OR=0.15,95%CI:0.040.61,p<0.05)or both sleep duration and PA recommendations(OR=0.24,95%CI:0.070.87,p<0.05)was associated with lower odds of repeating any grades.With respect to adaptive ability,participants who met only the PA recommendation of the 24-HMB were less likely to have difficulties dressing or bathing(OR=0.11,95%CI:0.020.66,p<0.05)than those who did not.For participants who met all 3 recommendations(OR=0.38,95%CI:0.150.99,p=0.05),the odds of being victimized by bullying was lower.Participants who adhered to both sleep duration and PA recommendations were less likely to present with severe behavioral problems(OR=0.17,95%CI:0.040.71,p<0.05)than those who did not meet those guidelines.Conclusion:Significant associations were found between adhering to 24-HMB guidelines and selected QoL indicators.These findings highlight the importance of maintaining a healthy lifestyle as a key factor in promoting and preserving the QoL of children with ASD. 展开更多
关键词 24-hour movement guidelines Autism spectrum disorder Physical activity Quality of life
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Interdialytic 24-Hours Ambulatory Blood Pressure versus Dialysis Unit Blood Pressure for the Diagnosis of Electrocardiographic-Left Ventricular Hypertrophy in Chronic Hemodialysis Black Patients 被引量:1
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作者 Cédric Kabemba Ilunga Francois Bompeka Beka Lepira +8 位作者 Jean Robert Rissassi Makulo Yves Lubenga Trésor Mvunzi Noel Utshudi Aliocha Nkodila Vieux Momeme Mokoli Ernest Kiswaya Sumaili Nazaire Mangani Nseka Eleuthère Vita Kintoki 《World Journal of Cardiovascular Diseases》 2019年第11期846-856,共11页
Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours A... Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours ABPM vs. dialysis unit BPs for the diagnosis of ECG-LVH in steady state chronic hemodialysis black patients. Methods: From March 31 to September 30, 2018, interdialytic ABPM was performed after a mid-week hemodialysis session for 24 hours using a Spacelab 90207 ABPM monitor in the non-access arm in 45 stable chronic hemodialysis black patients (age ≥ 20 years, hemodialysis for at least 3 months and informed consent) attending 3 hemodialysis centers in Kinshasa. Ambulatory BP was recorded every 20 minutes during the day (6 AM to 10 PM) and every 30 minutes during the night (10 PM to 6 AM). ECG-LVH was defined using Cornell product criteria. ROC curve method was used to assess the performance of dialysis unit BPs vs. interdialytic 24-hours ABPM in diagnosing ECG-LVH. P 0.05 defined the level of statistical significance. Results: Whatever the method of BP measurement, all the SBP values were related to ECG-LVH with similar AUC and overlapping 95% CI;however, they were not significantly different from each other. 24-hours interdialytic ambulatory SBP (AUC 0.748;95% CI 0.58 - 0.94) had the highest area under the curve. Conclusion: The present study showed that although all the two BP measurement methods equally detected ECG-LVH, 24-hours ABPM tended to have the highest diagnostic performance. 展开更多
关键词 24-hours ABPM Dialysis Unit BPs ECG-LVH Diagnostic Performance Chronic Hemodialysis Black Africans
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The nurses’ voice of working in a newly established community based 24-hour support center for people with psychiatric disabilities 被引量:1
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作者 Ann-Christin Janlov Agneta Berg 《Open Journal of Nursing》 2013年第2期195-201,共7页
This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the me... This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the mental health reform in Sweden in 1995 where the communities (in Sweden called municipalities) were given the responsibility to establish service and support to people with severe psychiatric disabilities, they have struggled in finding suitable forms of these kinds of areas. In 2010, this led to the creation and development of a new center aiming to provide services and support based on the expressed needs of people with physchiatric disability in a community located in southern Sweden. During 2011, a total of three group interviews were performed to capture the employed nurses’ perceptions of this newly established SC. The interview texts were analyzed by way of qualitative content analysis. A first reading of the interview texts revealed that the nurses’ perceptions of the service center were unwaveringly positive but that their beliefs about who the specific target group were differed. The main finding was summarized by the theme: Making a difference—on an individual, professional, and organizational level. The sub themes were: 24-hour availability, unclear assignment, and preventing mental illness. The findings indicate a need for a community round-the-clock service center in this Swedish community and a more clear definition of the target group. 展开更多
关键词 Psychiatric Disability Mental Health Nursing Community Mental Health Service 24-hour Service Center Qualitative Content Analysis
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China introduces the 24-hour rule
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作者 Bergami Roberto 《Chinese Business Review》 2009年第3期1-7,共7页
Recently, international movement measures that may be causing tension between the of cargo had been the subject of increasing border control needs for security and the needs for trade facilitations. On the one hand cu... Recently, international movement measures that may be causing tension between the of cargo had been the subject of increasing border control needs for security and the needs for trade facilitations. On the one hand customs authorities are charged with the responsibility for policing a country's borders, and consequently they need to have in place measures to ensure that only legitimate trade takes place and that this trade does not present security concerns. On the other hand we have the requirements of traders, who benefit from an environment of trade facilitation with speedy and efficient movement of cargo across international borders, with minimal bureaucratic intervention. This paper focuses on and provides early discussion and comments on the possible ramifications of the introduction of the 24-hour rule in China, effective for all exports and imports of sea freight container traffic since January 1, 2009. The new rules will have significant impact on the logistics flows of exporters and importers alike. Specifically, the reporting requirements timelines are likely to result in increased costs in cargo processing at wharves that traders will have to bear; place added pressure on storage facilities at wharves, or at container depots; and may additionally increase the amount of inventory buffer because of the timing of the data reporting requirements. The paper concludes that security needs have prevailed over trade facilitation considerations and that traders should urgently implement a review of existing practices to ensure they comply with the China Customs requirements, whilst simultaneously minimizing cost increases. 展开更多
关键词 24-hour rule cargo security ANTI-TERRORISM international regulations China Customs
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The lived experience of a 24-hour support center for persons with psychiatric disabilities: Making me feel almost like an ordinary person
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作者 Ann-Christin Janlov Irene Persson Agneta Berg 《Open Journal of Nursing》 2014年第1期42-50,共9页
This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in ... This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in a Swedish community to better match and facilitate the disabled persons’ needs. In order to illuminate the disabled person’s experiences individual interview was performed. A phenomenological-hermeneutical method inspired by Paul Ricoeur was used to interpret the texts. After a naive reading, a structural analysis revealed two themes: 1), becoming aware of myself as a person, and 2) having a lifeline and belongingness. The comprehensive understanding was interpreted as meaning “Making me feel almost like an ordinary person”, which incorporated the person’s past with their present together with a direction for the future and hope for a more fulfilling life. 展开更多
关键词 Psychiatric Disability Lived Experience Community Mental Health Service 24-hour Service Center Phenomenological-Hermeneutical Method Mental Health Nursing
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Esophageal manometry and 24-hour pH monitoring in esophagus surgery:28-year Chinese experience in a single center
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作者 邓波 《外科研究与新技术》 2011年第3期164-164,共1页
Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in e-sophagus surgery. Methods From 1982 to 2010,patients with unspecific chest pain and undergone esophageal surger... Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in e-sophagus surgery. Methods From 1982 to 2010,patients with unspecific chest pain and undergone esophageal surgery were received esophageal manometry and 24-hour pH monitoring. Results Among the patients with 展开更多
关键词 Esophageal manometry and 24-hour pH monitoring in esophagus surgery pH
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Analysis of 24-hour Monitoring of Intraocular Pressure in 1055 Eyes 被引量:1
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作者 Bo Wang Tao Dai +3 位作者 Yu Zhao Chuanwen Gao Jianrong Liu Peng Chen 《眼科学报(英文版)》 CAS 2013年第3期119-123,共5页
Purpose:.To investigate the clinical significance of 24-hour monitoring of intraocular pressure(IOP).Methods: A total of 571 cases(1055 eyes) undergoing 24-hour monitoring of IOP in the Second People's Hospital of... Purpose:.To investigate the clinical significance of 24-hour monitoring of intraocular pressure(IOP).Methods: A total of 571 cases(1055 eyes) undergoing 24-hour monitoring of IOP in the Second People's Hospital of Zhengzhou between June 2012 and March 2013 were retrospectively analyzed.Results: Among all 1055 eyes,.298 had suspected glaucoma(28.2%); 390(37.0%) were diagnosed with glaucoma but received no treatment(312 with primary open angle glaucoma(POAG).and 78 with primary angle closure glaucoma(PACG));215(20.4%) were diagnosed with glaucoma and received medical treatment;. 132( 12. 5 %). underwent glaucoma filtration surgery;.and there were 20 others..Through 24-hour IOP monitoring,.104 among 298 cases with suspected glaucoma were diagnosed with normal tension glaucoma(NTG),.110 with POAG,.and 28 with the secondary glaucoma..Condition assessment and treatment plans were presented for 390 glaucoma cases receiving no treatment..Adjustment was made in the medical treatment of 138 eyes..Following glaucoma filtration surgery,.52 eyes received clinical advice on subsequent treatment.Conclusion: The simplified 24-hour IOP monitoring method is readily accepted by patients,.which is of great significance for providing guidance on the diagnosis of glaucoma and the assessment of the efficacy of glaucoma surgery..However,one-time 24-hour IOP monitoring is not sufficiently efficacious to make a definite diagnosis of NTG..Therefore,.long-term follow-up and repeated 24-hour IOP monitoring are required to diagnose NTG,.along with a variety of related examinations. 展开更多
关键词 监测分析 小时 眼压 青光眼 临床意义 NTG 监测方法 原发性
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预防大学生肥胖的24 h活动行为最佳时间组合研究
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作者 陈小龙 金晶 +5 位作者 华佳禄 栗玉玉 潘有加 潘奇 涂春景 王平 《中国全科医学》 北大核心 2026年第12期1525-1532,共8页
背景肥胖已成为我国日益严重的公共卫生挑战,患病率持续上升。研究表明,24 h活动行为与肥胖密切相关,但现有指南多对各活动行为分别提出推荐时间,尚未充分考虑其在24 h内的相互制约与协同作用。目的基于最佳时间使用成分数据分析方法,探... 背景肥胖已成为我国日益严重的公共卫生挑战,患病率持续上升。研究表明,24 h活动行为与肥胖密切相关,但现有指南多对各活动行为分别提出推荐时间,尚未充分考虑其在24 h内的相互制约与协同作用。目的基于最佳时间使用成分数据分析方法,探讨24 h活动行为与大学生肥胖相关指标的关系,并构建预防肥胖的活动时间组合。方法采用方便抽样法,于2024年4—6月选取杭州师范大学108名大学生为研究对象进行测试调查。使用加速度计测量24 h活动行为;通过标准化工具测量身高、体重、腰围等指标,计算BMI、腰臀比、腰高比,并采用InBody 720分析仪测定体脂百分比和内脏脂肪面积。通过构建成分线性回归模型、生成预测活动行为时间组合、预测肥胖相关指标估计值等步骤确定最佳时间组合时长和区间。结果24 h活动行为组合与大学生BMI(F=8.25,P<0.01)、体脂百分比(F=27.58,P<0.01)、腰围(F=13.90,P<0.01)、腰臀比(F=13.10,P<0.01)、腰高比(F=14.09,P<0.01)及内脏脂肪面积(F=7.04,P<0.01)具有相关性。预防大学生肥胖相关指标的24 h活动最佳时间组合为:中高强度身体活动(MVPA)131 min(110~140 min)、低强度身体活动(LPA)208 min(160~230 min)、久坐行为(SB)663 min(620~730 min)和睡眠时间(SLP)438 min(360~520 min)。结论24 h活动行为组合与大学生肥胖相关指标关系密切。所构建的最佳时间组合中,MVPA和SLP的最佳时长与现有指南相符,并对SB和LPA时长提出了一定建议,该研究为大学生24 h身体活动行为时间分配的科学优化和肥胖的防控提供了科学依据。 展开更多
关键词 身体活动 24小时活动行为 最佳时间组合 大学生 肥胖管理
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儿童24 h活动行为测评方法研究进展
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作者 项天乐 周娜 +1 位作者 李芳 曹梅娟 《中国全科医学》 北大核心 2026年第6期760-766,776,共8页
儿童24 h活动行为指儿童在一天24 h内经历的身体活动、久坐和睡眠行为。许多研究表明以上3种不同活动行为的组合及其时间分配对儿童的身心健康产生重要影响。如何有效、完整地测评儿童24 h活动行为,对进一步开展儿童时间使用的流行病学... 儿童24 h活动行为指儿童在一天24 h内经历的身体活动、久坐和睡眠行为。许多研究表明以上3种不同活动行为的组合及其时间分配对儿童的身心健康产生重要影响。如何有效、完整地测评儿童24 h活动行为,对进一步开展儿童时间使用的流行病学研究调查,以及进行儿童健康行为干预和指南具有积极意义。我国对于儿童24 h活动行为测评工具的相关研究尚处于探索阶段。本文对国外儿童24 h活动行为测评方法具体内容、应用以及优劣势进行综述,旨在借鉴国外经验的基础上结合我国文化背景和儿童成长环境,发展适合我国儿童24 h活动行为的测评方法,为了解我国儿童24 h活动行为提供科学、有效的测评工具。 展开更多
关键词 24 h活动行为 身体活动 久坐行为 睡眠 儿童 测评方法 综述
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受限的离线权:24小时待命工作模式与劳动者睡眠和健康的关联研究
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作者 李晓谕 李园园 《人口与发展》 北大核心 2026年第1期136-145,135,共11页
24小时待命工作模式已成为数字时代劳动形态的重要组成部分,对劳动者的睡眠和健康构成严峻挑战。研究基于2022年中国家庭追踪调查数据,利用逻辑斯特回归模型探究24小时待命工作模式与劳动者睡眠和健康的关联,并分析其作用机制与人群异... 24小时待命工作模式已成为数字时代劳动形态的重要组成部分,对劳动者的睡眠和健康构成严峻挑战。研究基于2022年中国家庭追踪调查数据,利用逻辑斯特回归模型探究24小时待命工作模式与劳动者睡眠和健康的关联,并分析其作用机制与人群异质性。研究发现,24小时待命工作模式与劳动者睡眠不足概率增加、睡眠质量受损、自评健康变差和抑郁症状风险提高存在显著关联;该工作模式通过降低工作满意度间接损害睡眠与健康,且还会通过引发睡眠不足与睡眠质量变差加剧健康风险;不同性别、年龄和职业类型群体受影响程度存在差异,女性、中年及以上群体和蓝领劳动者睡眠不足风险较高,而男性的自评健康较差。研究表明,应重视并保障劳动者的“离线权”,维护劳动者的休息与健康权益。 展开更多
关键词 24小时待命工作模式 睡眠问题 健康风险 离线权
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高眼压症患者的24 h眼压波动规律及其临床意义
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作者 郑久胜 刘雯婷 《中国眼耳鼻喉科杂志》 2026年第1期22-26,共5页
目的分析高眼压症患者24 h眼压的波动特点及昼夜波动规律,以期为高危青光眼患者的早期发现提供参考依据。方法收集2016年1月—2019年6月期间在复旦大学附属华东医院眼科门诊诊断为高眼压症的患者63例(126眼),后入院行24 h眼压检查,用非... 目的分析高眼压症患者24 h眼压的波动特点及昼夜波动规律,以期为高危青光眼患者的早期发现提供参考依据。方法收集2016年1月—2019年6月期间在复旦大学附属华东医院眼科门诊诊断为高眼压症的患者63例(126眼),后入院行24 h眼压检查,用非接触性眼压计从早9:00起每隔2 h测量眼压1次,至次日7:00结束。分析患者的平均眼压,峰值眼压及时间点,谷值眼压及时间点,昼夜眼压波动及双眼眼压差值及其分布情况。结果126眼高眼压症患者的平均眼压为(19.01±1.89)mmHg(1 mmHg=0.133 kPa),平均峰值眼压为(22.62±2.54)mmHg,平均谷值眼压为(15.83±2.22)mmHg,平均昼夜眼压波动为(6.84±2.36)mmHg。峰值及谷值眼压分布最多的时间点分别为凌晨3:00及夜晚21:00,构成比分别为21.43%(27/126)及19.84%(25/126),大部分患者的峰值眼压时间点在门诊时间之外。昼夜眼压波动位于5~8 mmHg范围内的占比最大,占50.79%(64/126)。21例患者行24 h眼压检查后发现眼压波动范围超过正常,占比为33.33%(21/63)。结论24 h眼压监测可以为高眼压症患者提供较多有价值的眼压信息,利于高危患者的早期发现及后续加强随访。若条件允许,应该将24 h眼压监测作为高眼压症患者的必要检查手段。 展开更多
关键词 高眼压症 24 h眼压 昼夜眼压波动 诊断
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活动平板运动试验联合24h动态心电图对隐性冠心病的诊断价值
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作者 郭诗韵 吴红年 《湖北科技学院学报(医学版)》 2026年第1期58-61,共4页
目的 研究活动平板运动试验(TET)联合24h动态心电图诊断隐匿性冠心病的价值。方法 选择我院就诊的110例疑诊隐匿性冠心病患者进行TET联合24h动态心电图检查诊断,以冠状动脉造影(CAG)为金标准,比较分析TET联合24h动态心电图诊断隐匿性冠... 目的 研究活动平板运动试验(TET)联合24h动态心电图诊断隐匿性冠心病的价值。方法 选择我院就诊的110例疑诊隐匿性冠心病患者进行TET联合24h动态心电图检查诊断,以冠状动脉造影(CAG)为金标准,比较分析TET联合24h动态心电图诊断隐匿性冠心病的价值。结果 CAG诊断阳性101例,冠脉狭窄程度:轻度39例,中度55例,重度7例。101例冠状动脉检查阳性患者中,METs、运动峰值HR、运动峰值SBP、ΔHR1及ΔHR2均低于阴性组(P均<0.05);TET联合24h动态心电图检测的灵敏度及阴性预测值,特异度及kappa值高于单项检测(P均<0.05)。结论 TET与24h动态心电图两者联合检测更能明确诊断隐匿性冠心病,或可替代CAG检查作为筛查疑似隐匿性冠心病的无创性检查方法。 展开更多
关键词 隐匿性冠心病 活动平板运动试验 24H动态心电图 冠状动脉造影
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城乡隐蔽性高血压患者24 h动态血压与主要不良心血管事件的剂量-效应关系
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作者 董梅 孙旭杜 +3 位作者 刘洁 史苏娜 郑华松 杨柳 《实用临床医药杂志》 2026年第2期77-83,共7页
目的探讨城乡隐蔽性高血压(MH)患者24 h动态血压与主要不良心血管事件(MACE)的剂量-效应关系。方法回顾性选取在邢台市中心医院体检中心完成体检且临床资料完整的人员为研究对象,从中随机抽取180例MH患者作为病例组,并随机抽取120例血... 目的探讨城乡隐蔽性高血压(MH)患者24 h动态血压与主要不良心血管事件(MACE)的剂量-效应关系。方法回顾性选取在邢台市中心医院体检中心完成体检且临床资料完整的人员为研究对象,从中随机抽取180例MH患者作为病例组,并随机抽取120例血压正常者作为对照组。比较2组24 h动态血压参数[24 h收缩压(24 hSBP)、24 h舒张压(24 hDBP)、日间舒张压(dDBP)、日间收缩压(dSBP)、夜间舒张压(nDBP)、夜间收缩压(nSBP)]。根据是否发生MACE,将病例组患者分为MACE亚组和N-MACE亚组,比较其一般资料和24 h动态血压。基于限制性立方样条(RCS)分析24 h动态血压与MACE的剂量-效应关系,并评估24 h动态血压预测MACE的效能、准确性和临床效用。结果病例组24 hSBP、24 hDBP、dDBP、dSBP、nDBP、nSBP均高于对照组,差异有统计学意义(P<0.05)。MACE亚组患者体质量指数、腰围、24 hSBP、24 hDBP、同型半胱氨酸(Hcy)水平均高于N-MACE亚组,四肢骨骼肌质量指数(RASMI)低于N-MACE亚组,差异有统计学意义(P<0.05)。RCS分析显示,当24 hSBP≥135 mmHg时,其值升高,MACE发生风险增加,而当24 hSBP<135 mmHg时,其值降低,MACE发生风险也升高;当24 hDBP≥77 mmHg时,24 hDBP与MACE发生风险呈正相关,而当24 hDBP<77 mmHg时,24 hDBP与MACE发生风险无显著关联。受试者工作特征曲线分析显示,24 hSBP、24 hDBP单独及联合预测MACE的曲线下面积(AUC)依次为0.753、0.748、0.899,联合预测的AUC最大;校准曲线和决策曲线分析显示,24 hSBP与24 hDBP联合模型具有良好的预测准确性和临床净获益。结论城乡MH患者的24 h动态血压异常与MACE发生呈非线性剂量-效应关系,即当24 hSBP≥135 mmHg或24 hDBP≥77 mmHg时,MACE发生风险显著增加,且24 hSBP与24 hDBP联合应用对MACE具有良好的预测效能。 展开更多
关键词 城乡居民 隐蔽性高血压 24 h动态血压 主要不良心血管事件 剂量-效应关系 限制性立方样条 血压变异性 决策曲线分析
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Can spot urine measurement be a substitute for 24-hour urine measurement to estimate sodium intake in adolescents?
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作者 Jie Dong Xiaoyuan Zhao +2 位作者 Hongbo Dong Yinkun Yan Jie Mi 《Pediatric Investigation》 CSCD 2021年第1期12-20,共9页
Importance:Several methods have been established in recent decades that allow use of spot urine to estimate dietary sodium intake.However,their accuracies have been controversial in children.Objective:To validate the ... Importance:Several methods have been established in recent decades that allow use of spot urine to estimate dietary sodium intake.However,their accuracies have been controversial in children.Objective:To validate the performance of three commonly used methods-the Kawasaki,Tanaka,and International Cooperative Study on Salt,Other Factors,and Blood Pressure(INTERSALT)methods.Additionally,this study explored the accuracies of the Tanaka and INTERSALT methods by using spot urine samples taken at four separate times.Method:Forty-one adolescents aged 14 to 16 years completed two non-consecutive 24-hour urine collections and their mean values were used as reference data.The second-morning urine was used for assessment with the Kawasaki method;a casual spot urine and spot urine samples taken at four separate times(morning,afternoon,evening,and overnight)were used for assessment with the Tanaka and INTERSALT methods.Results:The mean differences were 1801 mg,542 mg,47 mg,and-31 mg for the Kawasaki,Tanaka,INTERSALT 1(with potassium),and INTERSALT2(without potassium)methods with their required spot urine,respectively.The proportions of relative difference levels within±10%were 4.9%for the Kawasaki method,19.5%for the Tanaka method,36.6%for the INTERSALT 1 method,and 36.6%for the INTERSALT2 method.Interpretation:The INTERSALT method seemed to provide minimally biased estimations of mean population sodium intake with casual spot urine.However,there is a need to be cautious regarding inconsistencies in estimation among different levels of sodium intake.The methods assessed in this study were unable to accurately estimate sodium intake at the individual level. 展开更多
关键词 Adolescents Spot urine Sodium 24-hour urine
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Research progress of 24-hour movement behaviors in chronic non-communicable disease
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作者 Rong-Xuan Li Qing-Qing Fan Di Cui 《Life Research》 2024年第3期24-34,共11页
Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which inc... Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which include sleep,sedentary behavior(SED),and physical activity,underscore the inherent connections between different daily activities and the comprehensive impact of overall movement patterns on health.Evidence suggested that modifying patterns of 24-hour movement behaviors can aid in preventing and attenuating the progression of NCDs.This study systematically delineated the concept,evolution,analytical methods,and intrinsic associations of 24-hour movement behaviors,emphasizing their pivotal role in the prevention and management of NCDs such as obesity,mental disorders,cardiovascular diseases,diabetes,and renal diseases.Future research endeavors should focus on refining methodologies,broadening study populations,developing research tools,and exploring precise intervention strategies and interdisciplinary approaches to comprehensively enhance the effectiveness of NCDs prevention and management from a temporal perspective.Such efforts are poised to provide substantive guidance and support for public health practices. 展开更多
关键词 chronic non-communicable diseases 24-hour movement behaviors time-use epidemiology isotemporal substitution model compositional data analysis
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24小时尿电解质在慢性肾病中的变化及其参考区间的建立
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作者 徐曼 翟素平 +4 位作者 汪海霞 刘月 柴森 胡天喜 杜伟鹏 《中国医药指南》 2025年第22期108-112,共5页
目的分析24 h尿电解质在慢性肾病中的变化,初步评估其对慢性肾病的诊断价值,并制定本地区健康人群24 h尿钾、钠、钙、磷和镁的参考区间。方法收集2020年7月至2021年3月在南阳市中心医院住院的140例慢性肾病患者的24 h尿标本,同时收集本... 目的分析24 h尿电解质在慢性肾病中的变化,初步评估其对慢性肾病的诊断价值,并制定本地区健康人群24 h尿钾、钠、钙、磷和镁的参考区间。方法收集2020年7月至2021年3月在南阳市中心医院住院的140例慢性肾病患者的24 h尿标本,同时收集本地区166名健康人员的24 h尿标本,采用罗氏Cobas8000全自动生化分析仪测定钾、钠、钙、磷和镁,计算出24 h含量,比较慢性肾病组与健康人组之间的差异,根据健康人群制定这些指标的参考区间并进行验证。结果慢性肾病组24 h尿磷、镁均高于健康人组,24 h尿钙低于健康人组,差异均有统计学意义(P<0.05),两组尿钾、钠比较,差异无统计学意义(P>0.05);166名健康人员的24 h尿钾、钠、钙、磷和镁水平在性别上差异无统计学意义(P>0.05),在不同年龄组差异也无统计学意义(P>0.05),按照95%置信区间制定这些指标的正常参考值范围分别为16.70~80.70 mmol/d,73.10~261.80 mmol/d,1.05~8.11 mmol/d,5.22~27.44 mmol/d,1.27~5.23 mmol/d。结论24 h尿钾、钠、钙、磷水平变化在慢性肾病中有适当的筛查价值,可进一步研究其对慢性肾病进展的影响,尿镁水平是否有差异还需进一步参考慢性肾病不同分期再进一步确认;本地区健康人群24 h尿钾、钠、钙、磷和镁在性别和年龄上差异无统计学意义,本研究成功建立了中原某地区健康人群24 h钾、钠、钙、磷和镁的参考区间。 展开更多
关键词 慢性肾病 24 h尿钾 24 h尿钠 24 h尿钙 24 h尿磷 24 h尿镁 参考区间
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儿童万古霉素血药谷浓度、24小时药时曲线下面积/最低抑菌浓度与临床疗效及肾功能的相关性分析
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作者 李娟 何瑾 +1 位作者 吴晖 王茜 《儿科药学杂志》 2025年第10期9-13,共5页
目的:回顾性分析昆明医科大学第一附属医院应用万古霉素的患儿血药浓度结果,统计万古霉素血药谷浓度(C_(min))、24小时药时曲线下面积(AUC_(24h))/最低抑菌浓度(MIC)与临床疗效和肾功能的相关性,为儿童患者基于血药浓度结果调整万古霉... 目的:回顾性分析昆明医科大学第一附属医院应用万古霉素的患儿血药浓度结果,统计万古霉素血药谷浓度(C_(min))、24小时药时曲线下面积(AUC_(24h))/最低抑菌浓度(MIC)与临床疗效和肾功能的相关性,为儿童患者基于血药浓度结果调整万古霉素剂量提供参考。方法:回顾性收集2019年7月至2023年8月符合纳入标准和排除标准的患儿相关信息,采用组间比较及组内前后对照的分析方法考察不同万古霉素AUC_(24h)/MIC、C_(min)区间与临床疗效及肾功能的相关性。绘制受试者工作特征(ROC)曲线评估AUC_(24h)/MIC、C_(min)对临床疗效及肾损伤的预测效能。结果:共144例患儿纳入研究,AUC_(24h)/MIC≤400 mg·h/L、400 mg·h/L<AUC_(24h)/MIC≤600 mg·h/L及AUC_(24h)/MIC>600 mg·h/L的3组患儿间万古霉素AUC_(24h)/MIC与临床有效率及微生物清除率比较差异均无统计学意义(P>0.05);C_(min)≤10μg/mL、10μg/mL<C_(min)≤20μg/mL及C_(min)>20μg/mL 3组患儿临床有效率及微生物清除率比较差异均无统计学意义(P>0.05);3组患儿使用万古霉前后Δ血肌酐、Δ尿素氮及Δ尿素氮/血肌酐比较差异均无统计学意义(P>0.05)。通过ROC曲线分析,AUC_(24h)/MIC的有效暴露阈值为310.40 mg·h/L,肾损伤的暴露阈值为528.11 mg·h/L,C_(min)的有效暴露阈值为5.63μg/mL,肾损伤的暴露阈值为11.51μg/mL。结论:儿童患者万古霉素AUC_(24h)/MIC、C_(min)的有效性及肾损伤阈值与成人比较存在差异,为保证临床疗效及安全性,有必要使儿童患者310.40 mg·h/L≤AUC_(24h)/MIC≤528.11 mg·h/L或5.63μg/mL≤C_(min)≤11.51μg/mL。但本研究样本量偏小,后续仍需大样本量研究加以验证。 展开更多
关键词 万古霉素 儿童 24小时药时曲线下面积/最低抑菌浓度 疗效 肾功能
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脑卒中患者出院后24 h活动行为达标情况及影响因素 被引量:1
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作者 卫佳宁 杨范家一 +2 位作者 郭丽娜 刘延锦 董小方 《护理学杂志》 北大核心 2025年第9期1-4,39,共5页
目的探讨脑卒中患者出院后24 h活动行为现状及相关影响因素,为制订针对性干预措施提供参考。方法采用便利抽样法,于2023年5-12月选取182例脑卒中出院患者为研究对象。采用一般资料调查表、Barthel指数评定量表、营养风险筛查2002、领悟... 目的探讨脑卒中患者出院后24 h活动行为现状及相关影响因素,为制订针对性干预措施提供参考。方法采用便利抽样法,于2023年5-12月选取182例脑卒中出院患者为研究对象。采用一般资料调查表、Barthel指数评定量表、营养风险筛查2002、领悟社会支持量表、运动锻炼自我效能感量表进行调查,并要求患者在出院后1周内连续7 d佩戴三轴加速度计,测量其出院后的身体活动、久坐行为和睡眠时间,以判断其是否满足24 h活动行为指南推荐的3项标准。结果脑卒中患者出院后每日睡眠时长为(7.12±1.46)h,久坐时间为(5.79±2.24)h,中高强度身体活动时间为1.04(0.47,1.93)h,其中分别有8、23、100、51例患者满足0、1、2、3项指南推荐标准。有序logistic回归分析结果显示,年龄、日常生活活动能力、领悟社会支持和运动锻炼自我效能感是脑卒中患者24 h活动行为达标的影响因素(均P<0.05)。结论脑卒中患者出院后24 h活动行为达标情况不佳,对年龄较大、日常生活活动能力较低、社会支持程度较弱及运动锻炼自我效能感较低者,护理人员应给予针对性健康教育,以提高此类患者的24 h活动行为水平。 展开更多
关键词 脑卒中 24 h活动行为 身体活动 久坐行为 睡眠 社会支持 运动锻炼 健康教育
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