期刊文献+
共找到819篇文章
< 1 2 41 >
每页显示 20 50 100
New types of nondegenerate solitons for a(2+1)-dimensional coupled system
1
作者 Yong Meng Hafiz Wajahat Ahmed Riaz Ji Lin 《Communications in Theoretical Physics》 2025年第9期1-9,共9页
In this paper,we investigate the(2+1)-dimensional three-component long-wave-short-wave resonance interaction system,which describes complex systems and nonlinear wave phenomena in physics.By employing the Hirota bilin... In this paper,we investigate the(2+1)-dimensional three-component long-wave-short-wave resonance interaction system,which describes complex systems and nonlinear wave phenomena in physics.By employing the Hirota bilinear method,we derive the general nondegenerate N-soliton solution of the system,where each short-wave component contains N arbitrary functions of the independent variable y.The presence of these arbitrary functions in the analytical solution enables the construction of a wide range of nondegenerate soliton types.Finally,we illustrate the structural features of several novel nondegenerate solitons,including M-shaped,multiple double-hump,and sawtooth double-striped solitons,as well as interactions between nondegenerate solitons,such as dromion-like solitons and solitoffs,with the aid of figures. 展开更多
关键词 (2+1)-dimensional coupled system general nondegenerate N-soliton solution arbitrary functions modulation waveform
原文传递
Open-Ocean Shallow-Water Dynamics via a(2+1)-Dimensional Generalized Variable-Coefficient Hirota-Satsuma-Ito System: Oceanic Auto-B?cklund Transformation and Oceanic Solitons
2
作者 GAO Xin-yi 《China Ocean Engineering》 2025年第3期541-547,共7页
Recently, during the investigations on planetary oceans, Hirota-Satsuma-Ito-type models have been developed. In this paper, for a(2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system describing ... Recently, during the investigations on planetary oceans, Hirota-Satsuma-Ito-type models have been developed. In this paper, for a(2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system describing the fluid dynamics of shallow-water waves in an open ocean, non-characteristic movable singular manifold and symbolic computation enable an oceanic auto-B?cklund transformation with three sets of the oceanic solitonic solutions. The results rely on the oceanic variable coefficients in that system. Future oceanic observations might detect some nonlinear features predicted in this paper, and relevant oceanographic insights might be expected. 展开更多
关键词 OCEAN shallow water (2+1)-dimensional generalized variable-coefficient Hirota-Satsuma-Ito system singular manifold symbolic computation B?cklund transformation soliton
在线阅读 下载PDF
A 3-Dimensional Cargo Loading Algorithm for the Conveyor-Type Loading System
3
作者 Hyeonbin Jeong Young Tae Ryu +1 位作者 Byung Duk Song Sang-Duck Lee 《Computer Modeling in Engineering & Sciences》 2025年第3期2739-2769,共31页
This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discre... This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discrete derivatives and introducing logistics-related constraints.Optional consideration of the rotation of the cargoes was made to further enhance the optimality of the solutions,if possible to be physically implemented.Evaluation metrics were developed for accurate evaluation and enhancement of the algorithm’s ability to efficiently utilize the loading space and provide a high level of dynamic stability.Experimental results demonstrate the extensive robustness of the proposed algorithm to the diversity of cargoes present in Business-to-Consumer environments.This study contributes practical advancements in both cargo loading optimization and automation of the logistics industry,with potential applications in last-mile delivery services,warehousing,and supply chain management. 展开更多
关键词 3-dimensional loading automated loading system B2C logistics cargo loading algorithm conveyortype loading
在线阅读 下载PDF
Localized wave solutions and interactions of the (2+1)-dimensional Hirota-Satsuma-Ito equation
4
作者 巩乾坤 王惠 王云虎 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期409-416,共8页
This paper studies the(2+1)-dimensional Hirota-Satsuma-Ito equation.Based on an associated Hirota bilinear form,lump-type solution,two types of interaction solutions,and breather wave solution of the(2+1)-dimensional ... This paper studies the(2+1)-dimensional Hirota-Satsuma-Ito equation.Based on an associated Hirota bilinear form,lump-type solution,two types of interaction solutions,and breather wave solution of the(2+1)-dimensional Hirota-Satsuma-Ito equation are obtained,which are all related to the seed solution of the equation.It is interesting that the rogue wave is aroused by the interaction between one-lump soliton and a pair of resonance stripe solitons,and the fusion and fission phenomena are also found in the interaction between lump solitons and one-stripe soliton.Furthermore,the breather wave solution is also obtained by reducing the two-soliton solutions.The trajectory and period of the one-order breather wave are analyzed.The corresponding dynamical characteristics are demonstrated by the graphs. 展开更多
关键词 lump solution rogue wave solution breather wave solution (2+1)-dimensional Hirota-Satsuma-Ito equation
原文传递
Nonlocal symmetries,soliton-cnoidal wave solution and soliton molecules to a(2+1)-dimensional modified KdV system
5
作者 Jianyong Wang Bo Ren 《Communications in Theoretical Physics》 SCIE CAS CSCD 2024年第4期14-21,共8页
A(2+1)-dimensional modified KdV(2DmKdV)system is considered from several perspectives.Firstly,residue symmetry,a type of nonlocal symmetry,and the Bäcklund transformation are obtained via the truncated Painlev... A(2+1)-dimensional modified KdV(2DmKdV)system is considered from several perspectives.Firstly,residue symmetry,a type of nonlocal symmetry,and the Bäcklund transformation are obtained via the truncated Painlevéexpansion method.Subsequently,the residue symmetry is localized to a Lie point symmetry of a prolonged system,from which the finite transformation group is derived.Secondly,the integrability of the 2DmKdV system is examined under the sense of consistent tanh expansion solvability.Simultaneously,explicit soliton-cnoidal wave solutions are provided.Finally,abundant patterns of soliton molecules are presented by imposing the velocity resonance condition on the multiple-soliton solution. 展开更多
关键词 soliton-cnoidal wave solution nonlocal symmetry soliton molecule (2+1)-dimensional modified KdV system
原文传递
The Dbar-dressing method for the(2+1)-dimensional Date–Jimbo–Kashiwara–Miwa equation
6
作者 Shifei Sun Biao Li 《Communications in Theoretical Physics》 SCIE CAS CSCD 2024年第1期17-23,共7页
In this work,the(2+1)-dimensional Date–Jimbo–Kashiwara–Miwa(DJKM)equation is studied by means of the ■-dressing method.A new ■ problem has been constructed by analyzing the characteristic function and the Green’... In this work,the(2+1)-dimensional Date–Jimbo–Kashiwara–Miwa(DJKM)equation is studied by means of the ■-dressing method.A new ■ problem has been constructed by analyzing the characteristic function and the Green’s function of its Lax representation.Based on solving the ■ equation and choosing the proper spectral transformation,the solution of the DJKM equation is constructed.Furthermore,the more general solution of the DJKM equation can be also obtained by ensuring the evolution of the time spectral data. 展开更多
关键词 (2+1)-dimensional DJKM equation inverse spectral problem Green's function characteristic function ■-dressing method
原文传递
Rogue waves for the(2+1)-dimensional Myrzakulov–Lakshmanan-Ⅳ equation on a periodic background
7
作者 Xiao-Hui Wang Zhaqilao 《Communications in Theoretical Physics》 SCIE CAS CSCD 2024年第4期32-42,共11页
In this paper, the rogue wave solutions of the(2+1)-dimensional Myrzakulov–Lakshmanan(ML)-Ⅳ equation, which is described by five component nonlinear evolution equations, are studied on a periodic background. By usin... In this paper, the rogue wave solutions of the(2+1)-dimensional Myrzakulov–Lakshmanan(ML)-Ⅳ equation, which is described by five component nonlinear evolution equations, are studied on a periodic background. By using the Jacobian elliptic function expansion method, the Darboux transformation(DT) method and the nonlinearization of the Lax pair, two kinds of rogue wave solutions which are expressed by Jacobian elliptic functions dn and cn, are obtained.The relationship between these five kinds of potential is summarized systematically. Firstly, the periodic rogue wave solution of one potential is obtained, and then the periodic rogue wave solutions of the other four potentials are obtained directly. The solutions we find present the dynamic phenomena of higher-order nonlinear wave equations. 展开更多
关键词 rogue waves on a periodic background (2+1)-dimensional Myrzakulov-Lakshmanan-IV equation Darboux transformation Jacobian elliptic function
原文传递
Dynamics of Nonlinear Waves in(2+1)-Dimensional Extended Boiti-Leon-Manna-Pempinelli Equation
8
作者 SUN Junxiu WANG Yunhu 《应用数学》 北大核心 2024年第4期1103-1113,共11页
Based on the Hirota bilinear method,this study derived N-soliton solutions,breather solutions,lump solutions and interaction solutions for the(2+1)-dimensional extended Boiti-Leon-Manna-Pempinelli equation.The dynamic... Based on the Hirota bilinear method,this study derived N-soliton solutions,breather solutions,lump solutions and interaction solutions for the(2+1)-dimensional extended Boiti-Leon-Manna-Pempinelli equation.The dynamical characteristics of these solutions were displayed through graphical,particularly revealing fusion and ssion phenomena in the interaction of lump and the one-stripe soliton. 展开更多
关键词 Hirota bilinear method N-soliton solutions Breather solutions Lump solutions Interaction solutions (2+1)-dimensional extended Boiti-Leon-Manna-Pempinelli equation
在线阅读 下载PDF
Novel nonlinear wave transitions and interactions for(2+1)-dimensional generalized fifth-order Kd V equation
9
作者 Yan Li Ruoxia Yao Senyue Lou 《Communications in Theoretical Physics》 CSCD 2024年第12期24-33,共10页
The(2 + 1)-dimensional generalized fifth-order Kd V(2GKd V) equation is revisited via combined physical and mathematical methods. By using the Hirota perturbation expansion technique and via setting the nonzero backgr... The(2 + 1)-dimensional generalized fifth-order Kd V(2GKd V) equation is revisited via combined physical and mathematical methods. By using the Hirota perturbation expansion technique and via setting the nonzero background wave on the multiple soliton solution of the 2GKd V equation, breather waves are constructed, for which some transformed wave conditions are considered that yield abundant novel nonlinear waves including X/Y-Shaped(XS/YS),asymmetric M-Shaped(MS), W-Shaped(WS), Space-Curved(SC) and Oscillation M-Shaped(OMS) solitons. Furthermore, distinct nonlinear wave molecules and interactional structures involving the asymmetric MS, WS, XS/YS, SC solitons, and breathers, lumps are constructed after considering the corresponding existence conditions. The dynamical properties of the nonlinear molecular waves and interactional structures are revealed via analyzing the trajectory equations along with the change of the phase shifts. 展开更多
关键词 (2+1)-dimensional generalized fifth-order KdV equation nonlinear molecular wave resonance soliton
原文传递
Bifurcations, Analytical and Non-Analytical Traveling Wave Solutions of (2 + 1)-Dimensional Nonlinear Dispersive Boussinesq Equation
10
作者 Dahe Feng Jibin Li Airen Zhou 《Applied Mathematics》 2024年第8期543-567,共25页
For the (2 + 1)-dimensional nonlinear dispersive Boussinesq equation, by using the bifurcation theory of planar dynamical systems to study its corresponding traveling wave system, the bifurcations and phase portraits ... For the (2 + 1)-dimensional nonlinear dispersive Boussinesq equation, by using the bifurcation theory of planar dynamical systems to study its corresponding traveling wave system, the bifurcations and phase portraits of the regular system are obtained. Under different parametric conditions, various sufficient conditions to guarantee the existence of analytical and non-analytical solutions of the singular system are given by using singular traveling wave theory. For certain special cases, some explicit and exact parametric representations of traveling wave solutions are derived such as analytical periodic waves and non-analytical periodic cusp waves. Further, two-dimensional wave plots of analytical periodic solutions and non-analytical periodic cusp wave solutions are drawn to visualize the dynamics of the equation. 展开更多
关键词 (2 + 1)-dimensional Nonlinear Dispersive Boussinesq Equation BIFURCATIONS Phase Portrait Analytical Periodic Wave Solution Periodic Cusp Wave Solution
在线阅读 下载PDF
An Amorphous 2-Dimensional Barcode
11
作者 Han Jin Shi Jin Junfeng Wu 《Journal of Cyber Security》 2020年第1期37-48,共12页
Most existing 2-dimensional barcodes are designed with a fixed shape and clear area.Having a fixed shape and clear area makes the barcode difficult to lay out with other text and pictures.To solve this problem,an amor... Most existing 2-dimensional barcodes are designed with a fixed shape and clear area.Having a fixed shape and clear area makes the barcode difficult to lay out with other text and pictures.To solve this problem,an amorphous 2-dimensional barcode is presented in this paper.The barcode uses encoding graph units to encode data.There are two key points in a 2-dimensional barcode:One is the encoding graph unit,the other is its encoding rules.Because encoding graph units of a 2-dimensional barcode are surrounded by other graphics,the units should be self-positioned and distinguished from other units.This paper presents an encoding graph unit generation algorithm,which is based on genetic algorithms.Encoding rules of the barcode are also given in this paper.Those rules include data encoding rules and encoding graph unit sequence arrangement rules.Data encoding rules are used to encode data to an encoding graph unit sequence.Encoding graph unit sequence arrangement rules are used to embed the unit sequence in the target picture.In addition to those rules,it also discussed the steps to restore encoding graph unit sequence from a picture.In the experiments section of this paper,an example is provided to encode a string and embed it in a car ad picture by the barcode.According to encoding rules of the barcode,those encoding graphic units can be scattered and embedded in a picture with other graphics,so amorphous 2-dimensional barcode has no fixed shape.Take advantage of this,designer can present a more elegant design to lay out barcodes with other graphic elements. 展开更多
关键词 2-dimensional bar code AMORPHOUS encoding graph unit genetic algorithm
在线阅读 下载PDF
结肠癌合并2型糖尿病患者血清lncRNA ANRIL、miR-181b-5p的表达及其与淋巴结转移的相关性
12
作者 潘勇娜 康金旺 常月锋 《实用临床医药杂志》 2025年第2期32-37,共6页
目的探讨结肠癌合并2型糖尿病(T2DM)患者血清长链非编码RNA INK4基因座中反义非编码RNA(lncRNA ANRIL)、微小RNA-181b-5p(miR-181b-5p)的表达及其与淋巴结转移的相关性。方法选取2019年5月—2022年8月本院收治的117例结肠癌合并T2DM患... 目的探讨结肠癌合并2型糖尿病(T2DM)患者血清长链非编码RNA INK4基因座中反义非编码RNA(lncRNA ANRIL)、微小RNA-181b-5p(miR-181b-5p)的表达及其与淋巴结转移的相关性。方法选取2019年5月—2022年8月本院收治的117例结肠癌合并T2DM患者为结肠癌合并T2DM组,并根据患者淋巴结转移情况将其分为淋巴结转移组56例和淋巴结未转移组61例。另选取同期体检的健康志愿者117例为对照组。采用反转录实时定量PCR检测血清lncRNA ANRIL、miR-181b-5p的相对表达水平。采用Logistic回归分析探讨影响结肠癌合并T2DM患者淋巴结转移的因素。绘制受试者工作特征(ROC)曲线分析血清lncRNA ANRIL、miR-181b-5p水平对结肠癌合并T2DM患者淋巴结转移的诊断价值。采用Pearson相关分析探讨结肠癌合并T2DM患者血清lncRNA ANRIL与miR-181b-5p表达的相关性。结果与对照组比较,结肠癌合并T2DM组患者血清lncRNA ANRIL水平升高,miR-181b-5p水平降低,差异均有统计学意义(P<0.01)。与淋巴结未转移组比较,淋巴结转移组患者血清lncRNA ANRIL水平升高,miR-181b-5p水平降低,差异均有统计学意义(P<0.01)。淋巴结转移组与淋巴结未转移组患者TNM分期、分化程度以及糖化血红蛋白(HbA1C)比较,差异有统计学意义(P<0.05)。糖尿病史、TNM分期、分化程度、HbA1C以及lncRNA ANRIL均是淋巴结转移的影响因素(P<0.05),miR-181b-5p是影响淋巴结转移的保护因素(P<0.05)。血清lncRNA ANRIL与miR-181b-5p水平呈负相关(r=-0.440,P<0.001)。ROC曲线结果显示,血清lncRNA ANRIL、miR-181b-5p以及二者联合诊断淋巴结转移的曲线下面积(AUC)分别为0.800、0.837、0.930,联合诊断价值显著高于lncRNA ANRIL(Z=2.956,P=0.003)、miR-181b-5p(Z=2.117,P=0.034)单独诊断价值。结论结肠癌合并T2DM患者血清lncRNA ANRIL水平升高,miR-181b-5p水平降低,且二者与淋巴结转移具有一定相关性。 展开更多
关键词 结肠癌 2型糖尿病 长链非编码RNA INK4基因座中反义非编码RNA 微小RNA-181b-5p
暂未订购
miR-516b-5p靶向NSUN2对乳腺癌细胞增殖和侵袭的影响
13
作者 程欣然 范亚楠 +1 位作者 刘俊 皮亚平 《河北医学》 2025年第10期1585-1592,共8页
目的:探讨微小非编码RNA-516b-5p(miR-516b-5p)靶向RNA甲基转移酶家族成员2(NSUN2)对乳腺癌(BC)细胞增殖和侵袭的影响。方法:qRT-PCR实验检测BC癌组织、癌旁组织(n=45)及正常乳腺上皮细胞(MCF-10A)、BC细胞(MCF-7、MDA-MB-231、HCC1937)... 目的:探讨微小非编码RNA-516b-5p(miR-516b-5p)靶向RNA甲基转移酶家族成员2(NSUN2)对乳腺癌(BC)细胞增殖和侵袭的影响。方法:qRT-PCR实验检测BC癌组织、癌旁组织(n=45)及正常乳腺上皮细胞(MCF-10A)、BC细胞(MCF-7、MDA-MB-231、HCC1937)中miR-516b-5p、NSUN2 mRNA表达量。将MCF-7细胞分为NC组、miR-NC组、miR-516b-5p mimic组、sh-NC组、sh-NSUN2组、miR-516b-5p mimic+pcDNA-NC组、miR-516b-5p mimic+pcDNA-NSUN2组,通过克隆形成和Transwell侵袭实验分别检测各组MCF-7细胞增殖和侵袭能力;Western blot实验检测各组细胞中NSUN2、细胞周期蛋白1(CCND1)、细胞周期蛋白依赖性激酶1(CDK1)、基质金属蛋白酶2(MMP2)、基质金属蛋白酶9(MMP9)蛋白表达量;构建裸鼠BC移植瘤模型,并分为Model组、miR-516b-5p mimics组、miR-516b-5p mimic+pcDNA-NSUN2组,测量各组肿瘤质量和体积。结果:与癌旁组织相比,癌组织中miR-516b-5p表达量明显下降,NSUN2 mRNA表达量明显上升(P<0.05)。与MCF-10A细胞相比,MCF-7、MDA-MB-231、HCC1937细胞中miR-516b-5p表达量明显下降,NSUN2 mRNA表达量明显上升(P<0.05),其中MCF-7细胞以上指标变化趋势最为明显。与NC组相比,miR-NC组和sh-NC组细胞各指标无明显变化(P>0.05);与miR-NC组相比,miR-516b-5p mimic组细胞集落形成数量、侵袭细胞数减少,NSUN2 mRNA和NSUN2、CCND1、CDK1、MMP2、MMP9蛋白表达量均明显下降,miR-516b-5p表达量明显上升(P<0.05);与sh-NC组相比,sh-NSUN2组各指标变化趋势与miR-516b-5p mimic组一致(P<0.05);而在miR-516b-5p mimic+pcDNA-NSUN2组中各指标变化趋势与miR-516b-5p mimic组相反(P<0.05)。双荧光素酶实验证实miR-516b-5p与NSUN2存在靶向关系(P<0.05)。裸鼠成瘤实验中,与Model组相比,miR-516b-5p mimics组肿瘤组织质量和体积明显缩小(P<0.05);与miR-516b-5p mimics组相比,miR-516b-5p mimic+pcDNA-NSUN2组肿瘤组织质量和体积明显增大(P<0.05)。结论:miR-516b-5p可通过靶向下调NSUN2表达,抑制BC细胞增殖和侵袭。 展开更多
关键词 微小非编码RNA-516b-5p RNA甲基转移酶家族成员2 乳腺癌 增殖 侵袭
暂未订购
急性缺血性脑卒中患者血清LncRNA RMST,miR-582-5p表达水平与早期神经功能恶化及预后的相关性研究
14
作者 任建华 张然 +1 位作者 崔秀英 赵新 《现代检验医学杂志》 2025年第1期64-68,共5页
目的 探讨急性缺血性脑卒中(AIS)患者血清长链非编码RNA横纹肌肉瘤相关转录物-2(LncRNA RMST)和miR-582-5p的表达水平与早期神经功能恶化(END)及预后的相关性。方法 选取2021年1月~2022年12月期间承德市中心医院收治的129例AIS患者,并... 目的 探讨急性缺血性脑卒中(AIS)患者血清长链非编码RNA横纹肌肉瘤相关转录物-2(LncRNA RMST)和miR-582-5p的表达水平与早期神经功能恶化(END)及预后的相关性。方法 选取2021年1月~2022年12月期间承德市中心医院收治的129例AIS患者,并根据患者一周内是否出现END将患者分为END组(n=42)和非END组(n=87),另选取同期在该院体检的健康者59例作为健康组。采用qRT-PCR法检测各组血清LncRNA RMST,miR-582-5p水平。Pearson法对END患者血清LncRNA RMST,miR-582-5p水平相关性进行分析;绘制ROC曲线评估血清LncRNA RMST,miR-582-5p水平以及二者联合对AIS患者预后情况的效能分析。结果 健康组、非END组、END组血清LncRNA RMST水平(1.01±0.28,2.10±0.41,3.99±0.52)逐渐升高,miR-582-5p水平(1.02±0.23,0.86±0.16,0.73±0.15)逐渐降低,差异具有统计学意义(F=672.974,31.907,均P <0.05)。END患者血清LncRNA RMST水平与mi R-582-5p水平存在明显的负相关(r=-0.451,P<0.001)。血清LncRNA RMST,miR-582-5p水平联合诊断AIS患者预后的AUC(95%CI)为0.961(0.912~0.987),优于单独预测(Z=2.280,4.515,均P <0.05)。结论 血清LncRNA RMST,miR-582-5p水平与END关系密切,有望成为AIS患者预后的预测因子。 展开更多
关键词 长链非编码RNA横纹肌肉瘤相关转录物-2 微小RNA-582-5p 急性缺血性脑卒中 神经功能恶化
暂未订购
SOS1-IT1通过调控乙酰化修饰促进人子宫内膜癌细胞EZH2表达的机制
15
作者 刘弘扬 娄雪玲 +6 位作者 张荣静 封全灵 郭凯歌 王皓梵 李颖颖 万军虎 张林东 《解剖学报》 2025年第4期444-451,共8页
目的 探讨人子宫内膜癌细胞Ishikawa和RL95-2中SOS-Ras/Rac鸟嘌呤核苷酸交换因子1-内含子转录物1(SOS1-IT1)影响zeste同源物增强子2(EZH2)蛋白表达的分子机制。方法 在Ishikawa和RL95-2细胞系中利用慢病毒转染短发夹RNA(shRNA)和过表达... 目的 探讨人子宫内膜癌细胞Ishikawa和RL95-2中SOS-Ras/Rac鸟嘌呤核苷酸交换因子1-内含子转录物1(SOS1-IT1)影响zeste同源物增强子2(EZH2)蛋白表达的分子机制。方法 在Ishikawa和RL95-2细胞系中利用慢病毒转染短发夹RNA(shRNA)和过表达质粒方法,敲低和过表达SOS1-IT1,利用Real-time PCR、Western blotting和染色质免疫共沉淀等实验探究EZH2表达调控的机制。结果 SOS1-IT1与EZH2基因在人子宫内膜癌组织中的表达成正相关,敲低SOS1-IT1明显降低EZH2的表达,抑制Ishikawa和RL95-2细胞增殖和迁移,且能降低EZH2基因启动区组蛋白H3第27位点的赖氨酸(H3K27)乙酰化和CREB结合蛋白(CBP)的富集程度,而过表达SOS1-IT1则可以增加EZH2的表达量,并增强H3K27乙酰化和CBP的富集程度,且CBP可以结合SOS1-IT1 RNA,在敲低CBP时,这种结合能力减弱。结论 SOS1-IT1可以通过调控EZH2基因启动子区的乙酰化修饰水平促进子宫内膜癌细胞Ishikawa和RL95-2中EZH2的表达水平,进而影响子宫内膜癌细胞的增殖和迁移能力。 展开更多
关键词 子宫内膜癌 长链非编码RNA 鸟嘌呤核苷酸交换因子1-内含子转录物1 Zeste同源物增强子2 免疫印迹法
原文传递
lncRNA CASC2 吸附 miR-K11-3p 调控 SSI-1对JAK-STAT 信号通路的影响
16
作者 张静 彭靖淇 房新志 《广东医学》 2025年第10期1521-1526,共6页
目的 研究长链非编码RNA癌易感性候选基因2(long non-coding RNA cancer susceptibility candidate 2,lncRNA CASC2)吸附微小核糖核酸-K11-3p(miR-K11-3p)调控细胞因子信号传导抑制因子1(STAT-induced STAT inhibitor 1,SSI-1)对JAK-STA... 目的 研究长链非编码RNA癌易感性候选基因2(long non-coding RNA cancer susceptibility candidate 2,lncRNA CASC2)吸附微小核糖核酸-K11-3p(miR-K11-3p)调控细胞因子信号传导抑制因子1(STAT-induced STAT inhibitor 1,SSI-1)对JAK-STAT信号通路的影响。方法 采用生物信息学预测CASC2与miR-K11-3p及miR-K11-3p与SSI-1的靶向关系,并通过双荧光素酶实验验证;利用Western blot和双荧光素酶实验检测CASC2通过miR-K11-3p对SSI-1表达的影响;过表达CASC2后,采用Western blot及q-PCR方法检测Janus激酶(Janus kinase,JAK)、信号转导子与转录激活子(signal transducer and activator of transcription,STAT)和酪氨酸激酶2(tyrosine kinase 2,TYK2 )蛋白及mRNA表达情况。结果CASC2能够靶向吸附miR-K11-3p(P<0.01),且SSI-1被证实是miR-K11-3p的靶基因(P<0.01);CASC2通过miR-K11-3p调控SSI-1的表达(P<0.01);过表达CASC2后,JAK、STAT和TYK2蛋白水平及mRNA水平表达均下降(P<0.01)。结论 lncRNA CASC2通过吸附miR-K11-3p调控SSI-1表达影响JAK-STAT信号通路。提示CASC2可能作为临床治疗卡波西肉瘤的潜在生物靶点。 展开更多
关键词 癌易感性候选基因2 微小核糖核酸-K11-3p 细胞因子信号传导抑制因子1 JAK-STAT信号通路 卡波西肉瘤
暂未订购
A Variable Separation Approach to Solve the Integrable and Nonintegrable Models:Coherent Structures of the (2 + 1)-Dimensional KdV Eqnation 被引量:8
17
作者 TANG Xiao-Yan LOU Sen-Yue 《Communications in Theoretical Physics》 SCIE CAS CSCD 2002年第7期1-8,共8页
We study the localized coherent structures ofa generally nonintegrable (2+ 1 )-dimensional KdV equation via a variable separation approach. In a special integrable case, the entrance of some arbitrary functions leads ... We study the localized coherent structures ofa generally nonintegrable (2+ 1 )-dimensional KdV equation via a variable separation approach. In a special integrable case, the entrance of some arbitrary functions leads to abundant coherent structures. However, in the general nonintegrable case, an additional condition has to be introduced for these arbitrary functions. Although the additional condition has been introduced into the solutions of the nonintegrable KdV equation, there still exist many interesting solitary wave structures. Especially, the nonintegrable KdV equation possesses the breather-like localized excitations, and the similar static ring soliton solutions as in the integrable case. Furthermor,in the integrable case, the interaction between two travelling ring solitons is elastic, while in the nonintegrable case we cannot find even the single travelling ring soliton solution. 展开更多
关键词 variable SEPARATION approach INTEGRABLE and nonintegrable models (2+1)-dimensional SOLITONS
在线阅读 下载PDF
Exotic Localized Coherent Structures of New (2+1)-Dimensional Soliton Equation 被引量:8
18
作者 ZHANG Jie-Fang HUANG Wen-Hua ZHENG Chun-Long 《Communications in Theoretical Physics》 SCIE CAS CSCD 2002年第11期517-522,共6页
The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryf... The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryfunctions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types ofsolutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functionsappropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the numberof the peaks. 展开更多
关键词 variable separation approach coherent structures NEW (2+1)-dimensional SOLITON equation
在线阅读 下载PDF
Role of 2-dimensional Doppler echo-cardiography in screening portopulmonary hypertension in portal hypertension patients 被引量:7
19
作者 Hua, Rong Sun, Yong-Wei +4 位作者 Wu, Zhi-Yong Cheng, Wei Xu, Qing Cao, Hui Luo, Meng 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2009年第2期157-161,共5页
BACKGROUND: Portopulmonary hypertension (PPH) is difficult to recognize in the early and middle stages because it is frequently asymptomatic. As right ventricular function is impaired in patients with moderate and sev... BACKGROUND: Portopulmonary hypertension (PPH) is difficult to recognize in the early and middle stages because it is frequently asymptomatic. As right ventricular function is impaired in patients with moderate and severe PPH, any dramatic hemodynamic changes in liver transplantation or other procedures may result in death from pulmonary and cardiac events. In this study, we investigated the prevalence of PPH in patients with portal hypertension (PHT) mainly caused by hepatitis B virus, and evaluated the effect of 2-dimensional Doppler echocardiography (2D-ECHO) in screening for PPH. METHODS: One hundred and five PHT patients received transthoracic 2D-ECHO preoperatively, systolic pulmonary arterial pressure (SPAP, normal range <30 mmHg) and pulmonary acceleration time (PAT, normal range >= 120 msec) were measured to screen for PPH (positive result: SPAP >= 30 mmHg and/or PAT <100 msec). Subsequently, pulmonary hemodynamic parameters were measured by right heart catheterization (RHC) for definitive diagnosis of PPH. The results of the two methods were compared to assess the screening effect of 2D-ECHO. RESULTS: The prevalence of PPH in this study was 3.8% (4/105). About 90% (95/105) of patients had a detectable tricuspid regurgitation by 2D-ECHO and the mean SPAP was 27.7 +/- 5.9 mmHg. Twenty-two of these 95 patients had an SPAP >30 mmHg. The mean PAT of all patients was 140 23 msec and 5 were <100 msec. Twenty-two patients were screened out by 2D-ECHO and 4 were diagnosed by RHC. A positive significant correlation (r=0.55, P<0.01) was found between SPAP measured by 2D-ECHO and mean pulmonary artery pressure (MPAP) measured by RHC, and a weak but significant negative correlation (r=-0.27, P=0.005) existed between PAT and pulmonary vascular resistance (PVR). The sensitivity, specificity, agreement rate, positive predictive value and negative predictive value of the screening test were 100%, 82%, 83%, 18% and 100%, respectively. CONCLUSIONS: The prevalence of PPH in this study is lower than in Western countries. As a screening test, 2D-ECHO has very high sensitivity and negative predictive value. A negative test result can directly be used to exclude PPH, while a positive result should be confirmed by RHC. 展开更多
关键词 portopulmonary hypertension 2-dimensional Doppler echocardiography right heart catheterization PREVALENCE diagnosis
暂未订购
Study of (2+1)-Dimensional Higher-Order Broer-Kaup System 被引量:8
20
作者 WANG Ling LIU Xi-Qiang DONG Zhong-Zhou 《Communications in Theoretical Physics》 SCIE CAS CSCD 2007年第3期403-408,共6页
Painleve property and infinite symmetries of the (2+1)-dimensional higher-order Broer-Kaup (HBK) system are studied in this paper. Using the modified direct method, we derive the theorem of general symmetry gro.u... Painleve property and infinite symmetries of the (2+1)-dimensional higher-order Broer-Kaup (HBK) system are studied in this paper. Using the modified direct method, we derive the theorem of general symmetry gro.ups to (2+1)-dimensional HBK system. Based on our theorem, some new forms of solutions are obtained. We also find infinite number of conservation laws of the (2+1)-dimensional HBK system. 展开更多
关键词 2+1)-dimensional HBK system Painleve property SYMMETRIES exact solution conservation laws
在线阅读 下载PDF
上一页 1 2 41 下一页 到第
使用帮助 返回顶部