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Transmission ratio (T_n) in the radian direction normal to joints in 2-D compressional wave propagation in rock masses
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作者 Weidong Lei Jun Teng +1 位作者 Ashraf Mohamed Hefny Jian Zhao 《Journal of University of Science and Technology Beijing》 CSCD 2006年第3期199-206,共8页
The transmission ratio along the radian direction normal to the joints was studied in the Universal Distinct Element Code (UDEC). The variation of the transmission ratio with the ratio of joint spacing to wavelength... The transmission ratio along the radian direction normal to the joints was studied in the Universal Distinct Element Code (UDEC). The variation of the transmission ratio with the ratio of joint spacing to wavelength was generalized into a general curve, which was determined by two critical points. The relationship between the two critical points and the affecting factors, quantity of joints and the normalized normal stiffness of joints, were obtained. A prediction model of the transmission ratio in the radian direction normal to the joints was proposed. The proposed model was applied to a field explosion test. The estimated values of the peak particle velocity from the prediction model were compared with the field records. The comparisons showed that the prediction model of the transmission ratio in the direction normal to the joints in the process of 2-D compressional wave propagation through multiple parallel joints is reliable. 展开更多
关键词 2-d compressional wave wave propagation transmission ratio field explosion test
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Three-dimensional time-of-flight magnetic resonance angiography combined with high resolution T2-weighted imaging in preoperative evaluation of microvascular decompression 被引量:4
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作者 Chen Liang Ling Yang +2 位作者 Bin-Bin Zhang Shi-Wen Guo Rui-Chun Li 《World Journal of Clinical Cases》 SCIE 2022年第34期12594-12604,共11页
BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and H... BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and HFS caused by NVC. The judgement of NVC is a critical step in the preoperative evaluation of MVD, which is related to the effect of MVD treatment. Magnetic resonance imaging(MRI) technology has been used to detect NVC prior to MVD for several years. Among many MRI sequences, three-dimensional time-of-flight magnetic resonance angiography(3D TOF MRA) is the most widely used. However, 3D TOF MRA has some shortcomings in detecting NVC. Therefore, 3D TOF MRA combined with high resolution T2-weighted imaging(HR T2WI) is considered to be a more effective method to detect NVC.AIM To determine the value of 3D TOF MRA combined with HR T2WI in the judgment of NVC, and thus to assess its value in the preoperative evaluation of MVD.METHODS Related studies published from inception to September 2022 based on PubMed, Embase, Web of Science, and the Cochrane Library were retrieved. Studies that investigated 3D TOF MRA combined with HR T2WI to judge NVC in patients with TN or HFS were included according to the inclusion criteria. Studies without complete data or not relevant to the research topics were excluded. The Quality Assessment of Diagnostic Accuracy Studies checklist was used to assess the quality of included studies. The publication bias of the included literature was examined by Deeks’ test. An exact binomial rendition of the bivariate mixed-effects regression model was used to synthesize data. Data analysis was performed using the MIDAS module of statistical software Stata 16.0. Two independent investigators extracted patient and study characteristics, and discrepancies were resolved by consensus. Individual and pooled sensitivities and specificities were calculated. The I_(2) statistic and Q test were used to test heterogeneity. The study was registered on the website of PROSERO(registration No. CRD42022357158).RESULTS Our search identified 595 articles, of which 12(including 855 patients) fulfilled the inclusion criteria. Bivariate analysis showed that the pooled sensitivity and specificity of 3D TOF MRA combined with HR T2WI for detecting NVC were 0.96 [95% confidence interval(CI): 0.92-0.98] and 0.92(95%CI: 0.74-0.98), respectively. The pooled positive likelihood ratio was 12.4(95%CI: 3.2-47.8), pooled negative likelihood ratio was 0.04(95%CI: 0.02-0.09), and pooled diagnostic odds ratio was 283(95%CI: 50-1620). The area under the receiver operating characteristic curve was 0.98(95%CI: 0.97-0.99). The studies showed no substantial heterogeneity(I2 = 0, Q = 0.001 P = 0.50).CONCLUSION Our results suggest that 3D TOF MRA combined with HR T2WI has excellent sensitivity and specificity for judging NVC in patients with TN or HFS. This method can be used as an effective tool for preoperative evaluation of MVD. 展开更多
关键词 Three-dimensional time-of-flight magnetic resonance angiography High resolution T2 weighted imaging Neurovascular compression Microvascular decompression META-ANALYSIS
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2-D纳米片对聚丙烯酰胺溶液性质的影响规律
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作者 汪小宇 万向辉 +3 位作者 蒋文学 刘贺羚 肖琳波 吴雪梅 《石油化工》 北大核心 2025年第12期1737-1744,共8页
以BN为原料制备了二维(2-D)纳米片,构建了一种稳定的部分水解聚丙烯酰胺(HPAM)/2-D纳米片体系,利用FTIR、SEM、黏度测试等方法分析了2-D纳米片对HPAM的结构及性能的影响,并考察了该体系的驱油效果。实验结果表明,引入2-D纳米片使体系的... 以BN为原料制备了二维(2-D)纳米片,构建了一种稳定的部分水解聚丙烯酰胺(HPAM)/2-D纳米片体系,利用FTIR、SEM、黏度测试等方法分析了2-D纳米片对HPAM的结构及性能的影响,并考察了该体系的驱油效果。实验结果表明,引入2-D纳米片使体系的三维网状结构变得更加致密。2-D纳米片的加入增强了HPAM内部相互作用力,提升了体系的结构稳定性,进而提高HPAM溶液的黏度。0.04%(w)2-D纳米片/0.3%(w)HPAM体系的黏度提高率为18.75%,相比HPAM溶液具有良好的抗温性能、抗盐性能和抗剪切性能。在常温下,该体系的原油采收率能提高15.23%,高于HPAM溶液,有望用于油田驱油。 展开更多
关键词 2-d纳米片 部分水解聚丙烯酰胺 增黏 提高采收率
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4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶通过抑制mGluR5调控ERK1/2-SGK1信号通路改善小鼠创伤后应激障碍 被引量:1
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作者 何存宝 杨绍杰 朱国旗 《南方医科大学学报》 北大核心 2025年第4期765-773,共9页
目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6... 目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6只/组。采用行为学实验评价SPS模型组小鼠的PTSD样行为;Western blotting联合免疫荧光检测小鼠海马组织代谢型谷氨酸受体5(mGluR5)、p-ERK、SGK1蛋白表达水平;HE染色检测肝肾组织的病理损伤;分子对接和分子动力学验证化合物10b与mGluR5结合的稳定性。结果与对照组比较,SPS模型组小鼠表现出PTSD样行为(P<0.05),海马mGluR5和p-ERK蛋白表达升高,SGK1蛋白表达减少(P<0.05),而化合物10b可改善SPS组小鼠的行为异常(P<0.05),并抑制mGluR5表达,逆转p-ERK和SGK1的异常(P<0.05),且无明显肝肾毒性;分子对接和分子动力学结果显示10b与mGluR5结合稳定。结论化合物10b能改善SPS诱导的小鼠PTSD样行为,其机制可能和抑制mGluR5调节ERK1/2-SGK1信号通路相关。 展开更多
关键词 4-(芳基乙炔基)-吡咯并[2 3-d]嘧啶 创伤后应激障碍 代谢型谷氨酸受体5 单一长时程应激 ERK1/2 SGK1
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记忆事件触发机制下具有删失测量的2-D系统集员滤波 被引量:1
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作者 彭东杰 于浍 +1 位作者 刘殿臣 姚兆义 《控制与决策》 北大核心 2025年第8期2400-2408,共9页
在有限带宽网络下,针对受未知有界噪声和测量删失双重影响的二维(2-D)系统,研究基于记忆事件触发机制的系统集员滤波问题,旨在保证滤波性能的同时有效节约网络资源.首先,构建由F-M Ⅱ局部状态空间模型描述的2-D系统,并采用Tobit模型与... 在有限带宽网络下,针对受未知有界噪声和测量删失双重影响的二维(2-D)系统,研究基于记忆事件触发机制的系统集员滤波问题,旨在保证滤波性能的同时有效节约网络资源.首先,构建由F-M Ⅱ局部状态空间模型描述的2-D系统,并采用Tobit模型与饱和策略刻画及处理测量删失特性;其次,利用系统历史测量信息,提出一种新的记忆事件触发机制,以决定数据是否传输,从而降低其传输频率;再次,设计记忆事件触发依赖的集员滤波器,借助2-D数学归纳法和S-过程给出其存在的充分性判据;然后,通过求解一组凸优化问题,获得确保滤波误差限制在最小椭球内的滤波器增益;最后,以热交换过程为例,验证所提出滤波方案的实用性与优越性. 展开更多
关键词 2-d系统 测量删失 记忆事件触发机制 集员滤波
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Meso-damage evolution and mechanical characteristics of low-porosity sedimentary rocks under uniaxial compression 被引量:7
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作者 Jian-hua HU Dong-jie YANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第4期1071-1077,共7页
Low pore sedimentary rocks(from Guangxi, China) were subjected to uniaxial compression loading experiment under different initial stresses. The rock samples were investigated by nuclear magnetic resonance before and a... Low pore sedimentary rocks(from Guangxi, China) were subjected to uniaxial compression loading experiment under different initial stresses. The rock samples were investigated by nuclear magnetic resonance before and after the loading. The relationships between the mesoscopic rock damage and macroscopic mechanical parameters were established, and the initial damage stress of the low-porosity sedimentary rock was determined. The results showed that this type of rock has the initial stress of damage. When the initial loading stress is lower than the initial stress of damage, the T2 spectrum area of the rock sample gradually decreases, and the primary pores of the rock are further closed under the stress. The range of the initial stress of damage for this type of rock is 8-16 MPa. When the loading stress exceeds the initial stress of damage, the T2 spectrum area gradually increases, indicating that the porosity of the rock increases and microscopic damage of the rock appears. The rock damage degree is defined, and the nonlinear function between the rock damage degree and the initial loading stress is established. 展开更多
关键词 uniaxial compressive strength POROSITY T2 spectrum area rock damage degree
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2,4二氯苯氧乙酸(2,4-D)生产工艺综述 被引量:1
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作者 李浩桤 张华 《山东化工》 2025年第4期131-134,138,共5页
2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采... 2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采用先氯化法,其工艺依次为苯酚氯化制备2,4-二氯苯酚、2,4-二氯苯酚精制、酚钠盐制备、氯乙酸钠盐制备、缩合、酸化、干燥及废水处理。分别对各部分工艺进行了简单叙述,并结合国内外文献对生产工艺研究和进展进行了介绍。提出了目前2,4-D生产工艺中最迫切需要解决的问题和研究方向。 展开更多
关键词 2 4-二氯苯氧乙酸钠 2 4-d 氯化 缩合
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Microstructure and compression properties of fine Al2O3 particles dispersion strengthened molybdenum alloy 被引量:5
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作者 Tie-long SUN Liu-jie XU +4 位作者 Shi-zhong WEI Kun-ming PAN Wu-hui LI Yu-cheng ZHOU Zhi-min HUANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第12期3307-3321,共15页
The Mo alloys reinforced by Al2O3 particles were fabricated by hydrothermal synthesis and powder metallurgy. The microstructures of Mo-Al2O3 alloys were studied by using XRD, SEM and TEM. The results show that Al2O3 p... The Mo alloys reinforced by Al2O3 particles were fabricated by hydrothermal synthesis and powder metallurgy. The microstructures of Mo-Al2O3 alloys were studied by using XRD, SEM and TEM. The results show that Al2O3 particles, existing as a stable hexagonal phase(α-Al2O3), are uniformly dispersed in Mo matrix. The ultrafine α-Al2O3 particles remarkably refine grain size and increase dislocation density of Mo alloys. Moreover, a good interfacial bonding zone between α-Al2O3 and Mo grain is obtained. The crystallographic orientations of the interface of the Al2O3 particles and Mo matrix are [111]a-Al2O3//[111]Mo and(112)a-Al2O3//(0 11)Mo. Due to the effect of secondary phase and dislocation strengthening, the yield strength of Mo-2.0 vol.%Al2O3 alloy annealed at 1200 ℃ is approximately 56.0% higher than that of pure Mo. The results confirm that the addition of Al2O3 particles is a promising method to improve the mechanical properties of Mo alloys. 展开更多
关键词 Mo−Al2O3 alloys hydrothermal synthesis interface compression test dispersion strengthening
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Block sparse compressed sensing with frames:Null space property and l_(2)/l_(q)(0
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作者 WU Fengong ZHONG Penghong QIN Yuehai 《中山大学学报(自然科学版)(中英文)》 北大核心 2025年第3期173-182,共10页
This paper explores the recovery of block sparse signals in frame-based settings using the l_(2)/l_(q)-synthesis technique(0<q≤1).We propose a new null space property,referred to as block D-NSP_(q),which is based ... This paper explores the recovery of block sparse signals in frame-based settings using the l_(2)/l_(q)-synthesis technique(0<q≤1).We propose a new null space property,referred to as block D-NSP_(q),which is based on the dictionary D.We establish that matrices adhering to the block D-NSP_(q)condition are both necessary and sufficient for the exact recovery of block sparse signals via l_(2)/l_(q)-synthesis.Additionally,this condition is essential for the stable recovery of signals that are block-compressible with respect to D.This D-NSP_(q)property is identified as the first complete condition for successful signal recovery using l_(2)/l_(q)-synthesis.Furthermore,we assess the theoretical efficacy of the l2/lq-synthesis method under conditions of measurement noise. 展开更多
关键词 compressed sensing block sparse l2/lq-synthesis method null space property
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WELL-POSEDNESS OF 2-D HYPERBOLIC VISCOUS CAHN-HILLIARD EQUATION
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作者 Siyan GUO Jiangbo HAN Runzhang XU 《Acta Mathematica Scientia》 2025年第4期1438-1470,共33页
In this paper,we consider the initial boundary value problem for the 2-D hyperbolic viscous Cahn-Hilliard equation.Firstly,we prove the existence and uniqueness of the local solution by the Galerkin method and contrac... In this paper,we consider the initial boundary value problem for the 2-D hyperbolic viscous Cahn-Hilliard equation.Firstly,we prove the existence and uniqueness of the local solution by the Galerkin method and contraction mapping principle.Then,using the potential well theory,we study the global well-posedness of the solution with initial data at different levels of initial energy,i.e.,subcritical initial energy,critical initial energy and arbitrary positive initial energy.For subcritical initial energy,we prove the global existence,asymptotic behavior and finite time blowup of the solution.Moreover,we extend these results to the critical initial energy using the scaling technique.For arbitrary positive initial energy,including the sup-critical initial energy,we obtain the sufficient conditions for finite time blow-up of the solution.As a further study for estimating the blowup time,we give a unified expression of the lower bound of blowup time for all three initial energy levels and estimate the upper bound of blowup time for subcritical and critical initial energy. 展开更多
关键词 2-d hyperbolic viscous Cahn-Hilliard equation global existence finite time blow up exponential decay
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组织Spondin-2、MUC-1、Cath-D联合检测对宫颈癌术后复发的预测价值
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作者 董洁 李文凯 +3 位作者 王成静 刘畅 孔雪 刘玉珍 《临床误诊误治》 2025年第14期89-93,共5页
目的探讨组织脊椎蛋白-2(Spondin-2)、黏蛋白-1(MUC-1)、组织蛋白酶-D(Cath-D)联合检测对宫颈癌术后复发的预测价值。方法选取2019年4月至2021年4月就诊的235例宫颈癌手术患者,根据术后3年复发情况分为复发组和未复发组。统计并比较两... 目的探讨组织脊椎蛋白-2(Spondin-2)、黏蛋白-1(MUC-1)、组织蛋白酶-D(Cath-D)联合检测对宫颈癌术后复发的预测价值。方法选取2019年4月至2021年4月就诊的235例宫颈癌手术患者,根据术后3年复发情况分为复发组和未复发组。统计并比较两组人口学特征、临床病理特征及组织Spondin-2、MUC-1、Cath-D mRNA表达,采用Spearman相关分析临床病理特征与组织Spondin-2、MUC-1、Cath-D mRNA表达的相关性,采用多因素logistic回归分析宫颈癌术后复发的影响因素,采用受试者工作特征(ROC)曲线分析组织Spondin-2、MUC-1、Cath-D mRNA表达预测宫颈癌术后复发的价值。结果两组肿瘤直径、FIGO分期、分化程度、人乳头瘤病毒(HPV)感染、盆腔淋巴结转移比较存在显著差异(P<0.01)。复发组组织Spondin-2、MUC-1、Cath-D mRNA表达均高于未复发组(P<0.01)。Spearman相关分析显示,宫颈癌手术患者组织Spondin-2、MUC-1、Cath-D mRNA表达与肿瘤直径、FIGO分期、分化程度、HPV感染、盆腔淋巴结转移呈正相关(P<0.01)。多因素logistic回归分析显示,组织Spondin-2、MUC-1、Cath-D mRNA表达及HPV感染是宫颈癌术后复发的影响因素(P<0.01)。ROC曲线显示,组织Spondin-2、MUC-1、Cath-D mRNA表达联合预测宫颈癌术后复发的曲线下面积高于单一指标预测。结论组织Spondin-2、MUC-1、Cath-D联合检测对宫颈癌术后复发有较高的预测价值,利于临床早期预测宫颈癌术后复发、制订相应干预方案。 展开更多
关键词 宫颈肿瘤 手术治疗 复发 脊椎蛋白-2 黏蛋白-1 组织蛋白酶-d 相关性 预测价值
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子宫内膜癌患者血清NRP-2 VEGF-C和VEGF-D水平与其转移的相关性研究
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作者 邹歌 赵楠楠 +4 位作者 董建新 周剑利 袁金灵 高杰 郭艳娟 《安徽医学》 2025年第1期54-57,共4页
目的 探究子宫内膜癌(EC)患者血清神经菌毛蛋白-2(NRP-2)、血管内皮生长因子C(VEGF-C)和血管内皮生长因子D(VEGF-D)水平与其转移的关系。方法 选取2020年5月至2024年2月华北理工大学附属医院收治的147例EC患者为研究对象,以病理结果为... 目的 探究子宫内膜癌(EC)患者血清神经菌毛蛋白-2(NRP-2)、血管内皮生长因子C(VEGF-C)和血管内皮生长因子D(VEGF-D)水平与其转移的关系。方法 选取2020年5月至2024年2月华北理工大学附属医院收治的147例EC患者为研究对象,以病理结果为判定标准,根据癌细胞是否发生转移分为转移组(52例)和未转移组(95例),选取46例同期健康体检者为对照组,比较3组对象NRP-2、VEGF-C和VEGF-D水平,并分析与EC转移的关系。结果 转移组和未转移组的NRP-2、VEGF-C和VEGF-D水平均高于对照组,差异有统计学意义(P<0.05)。转移组的NRP-2、VEGF-C和VEGF-D水平均高于未转移组,差异有统计学意义(P<0.05)。转移组的内膜样癌占比、病理G1级占比和浸润深度≤1/2肌层占比均低于未转移组,差异有统计学意义(P<0.05)。非内膜样癌(OR=3.376,95%CI:1.037~10.995,P=0.043)、病理G2(OR=19.426,95%CI:2.895~130.338,P=0.002)或G3级(OR=11.311,95%CI:1.842~69.453,P=0.009)、浸润深度>1/2肌层(OR=10.683,95%CI:2.889~39.512,P<0.001)和高NRP-2水平(OR=1.847,95%CI:1.452~2.349,P<0.001)均是EC转移的独立危险因素。限制性立方样条分析结果显示,NRP-2与EC转移主要呈线性关系(P<0.001)。当NRP-2<17.35μg/L时,EC转移风险低;当NRP-2>17.35μg/L时,EC转移风险高。结论 子宫内膜癌患者血清NRP-2水平高与其转移有关,NRP-2水平升高是EC转移的独立预测因子。 展开更多
关键词 子宫内膜癌 神经菌毛蛋白-2 血管内皮生长因子-C 血管内皮生长因子-d 转移
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Study on Performance and Emission Characteristics of a Compression Ignition Engine Fueled with Diesel-2 Ethoxy Ethyl Acetate Blends
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作者 B. Deepanraj P. Lawrence +3 位作者 M. Kannan V. Nadanakumar S. Santhanakrishnan R. Senthil 《Engineering(科研)》 2011年第11期1132-1136,共5页
Diesel engines are the major contributors of various types of air polluting gases like carbon monoxide, oxides of nitrogen, smoke, etc. Improvement of fuel properties is essential for suppression of Diesel pollutant e... Diesel engines are the major contributors of various types of air polluting gases like carbon monoxide, oxides of nitrogen, smoke, etc. Improvement of fuel properties is essential for suppression of Diesel pollutant emissions along with the optimization of design factors and after treatment equipment. Studies conducted in the past have shown that a significant reduction were obtained in the emissions using oxygenates. This paper investigates the performance and emission characteristics of a direct injection Diesel engine fueled with 2 Ethoxy Ethyl Acetate (EEA) blends. Different fuel blends which contain 5%, 10% and 15% of EEA were prepared and the effect of these blends on performance and emissions were studied on a single cylinder direct injection Diesel engine. The blends were tested under different load conditions and the result showed that EEA blended fuels improves the performance of the engine and reduce the emission level significantly. 展开更多
关键词 2 Ethoxy ETHYL ACETATE DIESEL Performance Emission compression IGNITION Engine
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血清D-D、Runx2、CTX与骨质疏松性椎体压缩骨折患者PKP手术预后的关系
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作者 冯红卫 李超 及宁 《临床和实验医学杂志》 2025年第18期1931-1934,共4页
目的探讨血清D-二聚体(D-D)、核心结合因子2(Runx2)、I型胶原交联羧基末端肽(CTX)与骨质疏松性椎体压缩骨折(OVCF)患者经皮椎体后凸成形术(PKP)手术预后的关系。方法回顾性分析2022年1月至2024年3月沧州市人民医院收治的82例OVCF患者的... 目的探讨血清D-二聚体(D-D)、核心结合因子2(Runx2)、I型胶原交联羧基末端肽(CTX)与骨质疏松性椎体压缩骨折(OVCF)患者经皮椎体后凸成形术(PKP)手术预后的关系。方法回顾性分析2022年1月至2024年3月沧州市人民医院收治的82例OVCF患者的临床资料。患者行PKP手术后进行3个月随访,骨折愈合延迟患者11例纳入愈合不良组,骨折正常愈合患者71例纳入愈合良好组。收集、比较两组临床资料;分析OVCF患者PKP手术预后不良的影响因素;采用受试者操作特征(ROC)曲线分析D-D、Runx2、CTX预测OVCF患者PKP手术预后不良的价值。结果两组在性别、年龄、吸烟、饮酒、高血压及其他基础疾病、骨质疏松病程、骨折部位、骨水泥用量方面比较,差异均无统计学意义(P>0.05);愈合不良组糖尿病患者占比、有椎体裂隙征患者占比、D-D、CTX水平分别为36.36%、63.64%、(3.59±0.86)mg/L、(681.43±156.37)pg/mL,均高于愈合良好组[8.45%、25.35%、(0.92±0.26)mg/L、(355.72±91.06)pg/mL],Runx2水平为(0.51±0.04)μg/L,低于愈合良好组[(0.65±0.07)μg/L],差异均有统计学意义(P<0.05)。多因素Logistic回归分析显示,糖尿病、椎体裂隙征、D-D、CTX均是OVCF患者PKP手术预后不良的独立危险因素(P<0.05),Runx2是OVCF患者PKP手术预后不良的独立保护因素(P<0.05)。ROC曲线分析结果显示,D-D、Runx2、CTX单独及联合预测OVCF患者PKP手术预后不良的曲线下面积分别为0.786、0.824、0.850、0.928,敏感度分别为0.727、0.727、0.818、0.909,特异度分别为0.676、0.831、0.648、0.803(均P<0.05)。结论OVCF患者PKP手术预后与糖尿病、椎体裂隙征、D-D、Runx2、CTX有关,血清D-D及CTX升高、Runx2下降在患者骨折愈合延迟中有一定预测价值。 展开更多
关键词 骨质疏松性椎体压缩骨折 D-二聚体 核心结合因子2 I型胶原交联羧基末端肽 骨折愈合
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外源2,4-D对大豆再生过程的影响 被引量:8
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作者 李思楠 张超 +7 位作者 马彦龙 姜成涛 王玲爽 王传奇 于以成 李文滨 苏安玉 武小霞 《基因组学与应用生物学》 CAS CSCD 北大核心 2015年第6期1324-1332,共9页
为了寻找与大豆再生直接相关的基因,提高大豆转化率,解决大豆再生和转化困难的问题,以再生较好的东农50、再生较差绥农14两个大豆品种为材料,设计不同2,4-D浓度处理及不同取材时间,测定与大豆再生相关的IAA、SOD、PAL以及再生率指标。... 为了寻找与大豆再生直接相关的基因,提高大豆转化率,解决大豆再生和转化困难的问题,以再生较好的东农50、再生较差绥农14两个大豆品种为材料,设计不同2,4-D浓度处理及不同取材时间,测定与大豆再生相关的IAA、SOD、PAL以及再生率指标。结果表明:东农50在2,4-D浓度为8 mg/L、12 h处理下IAA浓度最大,比对照增加了76.9%,在2,4-D浓度为4 mg/L、4 h处理下SOD酶活性增幅最高,比对照增加了50.9%,在2,4-D浓度为4 m/L、8 h处理下PAL酶活性最高,比对照增加了76.4%;绥农14在2,4-D浓度为8 mg/L、2 h处理下IAA浓度最大,比对照增加97.1%,在2,4-D浓度为4 mg/L、12 h处理下SOD酶活性最高,比对照增加23.8%,在2,4-D浓度为2 mg/L、4 h处理下PAL酶活性最高,比对照增加53.9%。东农50和绥农14均在2,4-D浓度为4 mg/L时再生率最高,分别为87.6%和79.5%。依照该实验结果进行取材,应用转录组测序技术挖掘与大豆再生直接相关的基因,解释再生作用机理,解决大豆再生和转化受基因型限制的难题,为大豆基因功能研究及转化率的提高提供了理论和技术支持。 展开更多
关键词 大豆 再生 2 4-d IAA SOD PAL
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2,4-D丁酯对轮叶马先蒿的防除效果及对草地植被的影响 被引量:12
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作者 张晓艳 胡玉昆 +2 位作者 姬承东 郭正刚 公延明 《草业学报》 CSCD 北大核心 2009年第4期168-174,共7页
为有效灭除草地害草轮叶马先蒿,采用2,4-D丁酯在巴音布鲁克高寒草地进行了不同时期不同剂量化学防除试验。结果表明,防除轮叶马先蒿的最佳时期为盛花期;最佳药品用量是0.066 mL/m2;喷施2,4-D丁酯后,草地植被生态环境得到明显改善,轮叶... 为有效灭除草地害草轮叶马先蒿,采用2,4-D丁酯在巴音布鲁克高寒草地进行了不同时期不同剂量化学防除试验。结果表明,防除轮叶马先蒿的最佳时期为盛花期;最佳药品用量是0.066 mL/m2;喷施2,4-D丁酯后,草地植被生态环境得到明显改善,轮叶马先蒿被部分或完全灭除,优良牧草垂穗披碱草在草地群落中占据优势地位,同时杂类草新疆假龙胆受到一定的抑制,草地质量明显提高。 展开更多
关键词 高寒草地 2 4-d丁酯 轮叶马先蒿 化学防除
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在线GPC-GC/MS法测定苹果中2,4-D残留 被引量:7
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作者 张帆 张莹 +3 位作者 黄志强 李忠海 付善良 颜鸿飞 《分析试验室》 CAS CSCD 北大核心 2010年第5期36-39,共4页
建立在线GPC-GC/MS技术测定苹果中2,4-D残留的快速检测方法。采用正己烷振荡提取试样中2,4-D,正丁醇-H2SO4溶液衍生化,通过在线GPC-GC/MS系统自动完成从GPC净化、浓缩到GC/MS分析。该方法中2,4-D在实际样品检测中的平均加标回收率为87.9... 建立在线GPC-GC/MS技术测定苹果中2,4-D残留的快速检测方法。采用正己烷振荡提取试样中2,4-D,正丁醇-H2SO4溶液衍生化,通过在线GPC-GC/MS系统自动完成从GPC净化、浓缩到GC/MS分析。该方法中2,4-D在实际样品检测中的平均加标回收率为87.9%~99.9%,相对标准偏差(RSD)为2.7%~8.1%。方法的检测限为0.005 mg/kg。 展开更多
关键词 2 4-d 苹果 在线GPC-GC/MS法 衍生化
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三乙基苄基氯化铵催化下水介质中吡喃并[2,3-d]嘧啶衍生物的一步合成 被引量:7
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作者 梁静 张梅梅 +2 位作者 魏贤勇 宗志敏 王香善 《有机化学》 SCIE CAS CSCD 北大核心 2007年第11期1420-1423,共4页
以芳亚甲基丙二腈、1,3-二甲基巴比妥酸为原料,以水为溶剂,在100℃以三乙基苄基氯化铵(TEBAC)为催化剂合成了一系列的吡喃并[2,3-d]嘧啶衍生物,该方法具有反应条件温和,产率良好(78%~90%)和环境友好等优点.产物的结构通过IR,1H NMR和... 以芳亚甲基丙二腈、1,3-二甲基巴比妥酸为原料,以水为溶剂,在100℃以三乙基苄基氯化铵(TEBAC)为催化剂合成了一系列的吡喃并[2,3-d]嘧啶衍生物,该方法具有反应条件温和,产率良好(78%~90%)和环境友好等优点.产物的结构通过IR,1H NMR和元素分析表征,并进一步通过X射线衍射分析确证. 展开更多
关键词 吡喃并[2 3-d]嘧啶 TEBAC 合成
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2,4-D和根瘤菌对烟草类根瘤形成的影响 被引量:6
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作者 王煜 杨雨晗 +2 位作者 罗英 陈今朝 韩善华 《四川大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期1-3,共3页
烟草再生植株在含有 0 .3mg/L 2 ,4 D和 5× 10 8个 /L豌豆根瘤菌的Jensen培养基中 ,可以在其根部形成大量近似半球形和球形的类根瘤 .烟草再生植株的结瘤除受制于 2 ,4 D和根瘤菌的浓度外 ,还与根瘤菌的种类和加入根瘤菌与 2 ,4... 烟草再生植株在含有 0 .3mg/L 2 ,4 D和 5× 10 8个 /L豌豆根瘤菌的Jensen培养基中 ,可以在其根部形成大量近似半球形和球形的类根瘤 .烟草再生植株的结瘤除受制于 2 ,4 D和根瘤菌的浓度外 ,还与根瘤菌的种类和加入根瘤菌与 2 ,4 D的时期有关 . 展开更多
关键词 烟草再生植株 2 4-d 豌豆根瘤菌 结瘤率
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检测2,4-D的一次性安培型免疫传感器 被引量:6
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作者 蔡强 余若祯 +1 位作者 何苗 施汉昌 《环境科学》 EI CAS CSCD 北大核心 2005年第6期169-172,共4页
2,4-D是广泛使用的除草剂,以2,4-D为检测目标,研究了安培型免疫传感器.首先采用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐(EDC)作为交联剂制备2,4-D与BSA以及PLL的偶联物.用结合比1:16的2,4-D与偶联物制备兔抗血清.免疫传感器的制备包括... 2,4-D是广泛使用的除草剂,以2,4-D为检测目标,研究了安培型免疫传感器.首先采用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐(EDC)作为交联剂制备2,4-D与BSA以及PLL的偶联物.用结合比1:16的2,4-D与偶联物制备兔抗血清.免疫传感器的制备包括2个步骤,使用丝网印刷工艺制备一次性碳电极,然后通过戊二醛交联在电极表面固定2,4-D与多聚赖氨酸(PLL)的偶联物.待测水样与2,4-D抗血清和HRP酶标二抗进行间接免疫竞争反应.在HRP酶在邻苯二胺和H2O的共同作用下发生酶促反应,检测还原电流以反映2,4-D的浓度.试验了不同浓度抗血清和酶标二抗对检测信号的影响,结果表明,2,4-D的检测下限达到1.69ng/mL,线性区间1.69~30 000ng/mL,适合饮用水中2,4-D的检测要求. 展开更多
关键词 丝网印刷电极 2 4-d 安培型 免疫传感器
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