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Transmission ratio (T_n) in the radian direction normal to joints in 2-D compressional wave propagation in rock masses
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作者 Weidong Lei Jun Teng +1 位作者 Ashraf Mohamed Hefny Jian Zhao 《Journal of University of Science and Technology Beijing》 CSCD 2006年第3期199-206,共8页
The transmission ratio along the radian direction normal to the joints was studied in the Universal Distinct Element Code (UDEC). The variation of the transmission ratio with the ratio of joint spacing to wavelength... The transmission ratio along the radian direction normal to the joints was studied in the Universal Distinct Element Code (UDEC). The variation of the transmission ratio with the ratio of joint spacing to wavelength was generalized into a general curve, which was determined by two critical points. The relationship between the two critical points and the affecting factors, quantity of joints and the normalized normal stiffness of joints, were obtained. A prediction model of the transmission ratio in the radian direction normal to the joints was proposed. The proposed model was applied to a field explosion test. The estimated values of the peak particle velocity from the prediction model were compared with the field records. The comparisons showed that the prediction model of the transmission ratio in the direction normal to the joints in the process of 2-D compressional wave propagation through multiple parallel joints is reliable. 展开更多
关键词 2-d compressional wave wave propagation transmission ratio field explosion test
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Three-dimensional time-of-flight magnetic resonance angiography combined with high resolution T2-weighted imaging in preoperative evaluation of microvascular decompression 被引量:5
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作者 Chen Liang Ling Yang +2 位作者 Bin-Bin Zhang Shi-Wen Guo Rui-Chun Li 《World Journal of Clinical Cases》 SCIE 2022年第34期12594-12604,共11页
BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and H... BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and HFS caused by NVC. The judgement of NVC is a critical step in the preoperative evaluation of MVD, which is related to the effect of MVD treatment. Magnetic resonance imaging(MRI) technology has been used to detect NVC prior to MVD for several years. Among many MRI sequences, three-dimensional time-of-flight magnetic resonance angiography(3D TOF MRA) is the most widely used. However, 3D TOF MRA has some shortcomings in detecting NVC. Therefore, 3D TOF MRA combined with high resolution T2-weighted imaging(HR T2WI) is considered to be a more effective method to detect NVC.AIM To determine the value of 3D TOF MRA combined with HR T2WI in the judgment of NVC, and thus to assess its value in the preoperative evaluation of MVD.METHODS Related studies published from inception to September 2022 based on PubMed, Embase, Web of Science, and the Cochrane Library were retrieved. Studies that investigated 3D TOF MRA combined with HR T2WI to judge NVC in patients with TN or HFS were included according to the inclusion criteria. Studies without complete data or not relevant to the research topics were excluded. The Quality Assessment of Diagnostic Accuracy Studies checklist was used to assess the quality of included studies. The publication bias of the included literature was examined by Deeks’ test. An exact binomial rendition of the bivariate mixed-effects regression model was used to synthesize data. Data analysis was performed using the MIDAS module of statistical software Stata 16.0. Two independent investigators extracted patient and study characteristics, and discrepancies were resolved by consensus. Individual and pooled sensitivities and specificities were calculated. The I_(2) statistic and Q test were used to test heterogeneity. The study was registered on the website of PROSERO(registration No. CRD42022357158).RESULTS Our search identified 595 articles, of which 12(including 855 patients) fulfilled the inclusion criteria. Bivariate analysis showed that the pooled sensitivity and specificity of 3D TOF MRA combined with HR T2WI for detecting NVC were 0.96 [95% confidence interval(CI): 0.92-0.98] and 0.92(95%CI: 0.74-0.98), respectively. The pooled positive likelihood ratio was 12.4(95%CI: 3.2-47.8), pooled negative likelihood ratio was 0.04(95%CI: 0.02-0.09), and pooled diagnostic odds ratio was 283(95%CI: 50-1620). The area under the receiver operating characteristic curve was 0.98(95%CI: 0.97-0.99). The studies showed no substantial heterogeneity(I2 = 0, Q = 0.001 P = 0.50).CONCLUSION Our results suggest that 3D TOF MRA combined with HR T2WI has excellent sensitivity and specificity for judging NVC in patients with TN or HFS. This method can be used as an effective tool for preoperative evaluation of MVD. 展开更多
关键词 Three-dimensional time-of-flight magnetic resonance angiography High resolution T2 weighted imaging Neurovascular compression Microvascular decompression META-ANALYSIS
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Na_(2)SO_(4)溶液对滨海软土压缩及微观特性的影响
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作者 雷华阳 战持润 章纬地 《地下空间与工程学报》 北大核心 2026年第1期150-158,170,共10页
为了研究水化学环境对滨海软土力学性质的影响,对孔隙水环境为Na_(2)SO_(4)、不同含盐量的饱和土体开展了一维固结试验和微观扫描电镜试验。结果表明:随着含盐量的增加,滨海软土结构屈服应力减小,最大减小幅度为9.5%,压缩指数呈线性增大... 为了研究水化学环境对滨海软土力学性质的影响,对孔隙水环境为Na_(2)SO_(4)、不同含盐量的饱和土体开展了一维固结试验和微观扫描电镜试验。结果表明:随着含盐量的增加,滨海软土结构屈服应力减小,最大减小幅度为9.5%,压缩指数呈线性增大,渗透系数增大;当含盐量大于4%时,析出的芒硝晶体赋存于颗粒孔隙之间,土体骨架效应明显,导致土体结构屈服应力增大,压缩指数与渗透系数减小;扫描电镜图像显示含盐量的增加使滨海软土平均粒径增大,絮凝结构土颗粒增多。此外,建立了考虑含盐量和固结压力的滨海软土结构性参数,结果表明:随着固结压力的增加结构性参数减小;当固结压力小于结构屈服应力时,随着含盐量的增大,结构性参数先减小后增大,当固结压力大于结构屈服应力时,结构性参数随含盐量的增加变化不显著。 展开更多
关键词 Na_(2)SO_(4) 含盐量 压缩特性 结构性参数 微观孔隙结构
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2-D纳米片对聚丙烯酰胺溶液性质的影响规律
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作者 汪小宇 万向辉 +3 位作者 蒋文学 刘贺羚 肖琳波 吴雪梅 《石油化工》 北大核心 2025年第12期1737-1744,共8页
以BN为原料制备了二维(2-D)纳米片,构建了一种稳定的部分水解聚丙烯酰胺(HPAM)/2-D纳米片体系,利用FTIR、SEM、黏度测试等方法分析了2-D纳米片对HPAM的结构及性能的影响,并考察了该体系的驱油效果。实验结果表明,引入2-D纳米片使体系的... 以BN为原料制备了二维(2-D)纳米片,构建了一种稳定的部分水解聚丙烯酰胺(HPAM)/2-D纳米片体系,利用FTIR、SEM、黏度测试等方法分析了2-D纳米片对HPAM的结构及性能的影响,并考察了该体系的驱油效果。实验结果表明,引入2-D纳米片使体系的三维网状结构变得更加致密。2-D纳米片的加入增强了HPAM内部相互作用力,提升了体系的结构稳定性,进而提高HPAM溶液的黏度。0.04%(w)2-D纳米片/0.3%(w)HPAM体系的黏度提高率为18.75%,相比HPAM溶液具有良好的抗温性能、抗盐性能和抗剪切性能。在常温下,该体系的原油采收率能提高15.23%,高于HPAM溶液,有望用于油田驱油。 展开更多
关键词 2-d纳米片 部分水解聚丙烯酰胺 增黏 提高采收率
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4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶通过抑制mGluR5调控ERK1/2-SGK1信号通路改善小鼠创伤后应激障碍 被引量:1
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作者 何存宝 杨绍杰 朱国旗 《南方医科大学学报》 北大核心 2025年第4期765-773,共9页
目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6... 目的评价4-(芳基乙炔基)-吡咯并[2,3-d]嘧啶(10b)对单一长时程应激(SPS)诱导的小鼠创伤后应激障碍(PTSD)样行为及ERK1/2-SGK1信号通路的影响。方法将C57 BL/6小鼠随机分为正常对照组,SPS模型组,化合物10b低、中、高剂量组和帕罗西汀组,6只/组。采用行为学实验评价SPS模型组小鼠的PTSD样行为;Western blotting联合免疫荧光检测小鼠海马组织代谢型谷氨酸受体5(mGluR5)、p-ERK、SGK1蛋白表达水平;HE染色检测肝肾组织的病理损伤;分子对接和分子动力学验证化合物10b与mGluR5结合的稳定性。结果与对照组比较,SPS模型组小鼠表现出PTSD样行为(P<0.05),海马mGluR5和p-ERK蛋白表达升高,SGK1蛋白表达减少(P<0.05),而化合物10b可改善SPS组小鼠的行为异常(P<0.05),并抑制mGluR5表达,逆转p-ERK和SGK1的异常(P<0.05),且无明显肝肾毒性;分子对接和分子动力学结果显示10b与mGluR5结合稳定。结论化合物10b能改善SPS诱导的小鼠PTSD样行为,其机制可能和抑制mGluR5调节ERK1/2-SGK1信号通路相关。 展开更多
关键词 4-(芳基乙炔基)-吡咯并[2 3-d]嘧啶 创伤后应激障碍 代谢型谷氨酸受体5 单一长时程应激 ERK1/2 SGK1
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记忆事件触发机制下具有删失测量的2-D系统集员滤波 被引量:1
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作者 彭东杰 于浍 +1 位作者 刘殿臣 姚兆义 《控制与决策》 北大核心 2025年第8期2400-2408,共9页
在有限带宽网络下,针对受未知有界噪声和测量删失双重影响的二维(2-D)系统,研究基于记忆事件触发机制的系统集员滤波问题,旨在保证滤波性能的同时有效节约网络资源.首先,构建由F-M Ⅱ局部状态空间模型描述的2-D系统,并采用Tobit模型与... 在有限带宽网络下,针对受未知有界噪声和测量删失双重影响的二维(2-D)系统,研究基于记忆事件触发机制的系统集员滤波问题,旨在保证滤波性能的同时有效节约网络资源.首先,构建由F-M Ⅱ局部状态空间模型描述的2-D系统,并采用Tobit模型与饱和策略刻画及处理测量删失特性;其次,利用系统历史测量信息,提出一种新的记忆事件触发机制,以决定数据是否传输,从而降低其传输频率;再次,设计记忆事件触发依赖的集员滤波器,借助2-D数学归纳法和S-过程给出其存在的充分性判据;然后,通过求解一组凸优化问题,获得确保滤波误差限制在最小椭球内的滤波器增益;最后,以热交换过程为例,验证所提出滤波方案的实用性与优越性. 展开更多
关键词 2-d系统 测量删失 记忆事件触发机制 集员滤波
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Meso-damage evolution and mechanical characteristics of low-porosity sedimentary rocks under uniaxial compression 被引量:7
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作者 Jian-hua HU Dong-jie YANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第4期1071-1077,共7页
Low pore sedimentary rocks(from Guangxi, China) were subjected to uniaxial compression loading experiment under different initial stresses. The rock samples were investigated by nuclear magnetic resonance before and a... Low pore sedimentary rocks(from Guangxi, China) were subjected to uniaxial compression loading experiment under different initial stresses. The rock samples were investigated by nuclear magnetic resonance before and after the loading. The relationships between the mesoscopic rock damage and macroscopic mechanical parameters were established, and the initial damage stress of the low-porosity sedimentary rock was determined. The results showed that this type of rock has the initial stress of damage. When the initial loading stress is lower than the initial stress of damage, the T2 spectrum area of the rock sample gradually decreases, and the primary pores of the rock are further closed under the stress. The range of the initial stress of damage for this type of rock is 8-16 MPa. When the loading stress exceeds the initial stress of damage, the T2 spectrum area gradually increases, indicating that the porosity of the rock increases and microscopic damage of the rock appears. The rock damage degree is defined, and the nonlinear function between the rock damage degree and the initial loading stress is established. 展开更多
关键词 uniaxial compressive strength POROSITY T2 spectrum area rock damage degree
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2,4二氯苯氧乙酸(2,4-D)生产工艺综述 被引量:1
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作者 李浩桤 张华 《山东化工》 2025年第4期131-134,138,共5页
2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采... 2,4二氯苯氧乙酸是一种广泛应用的化学药品,简称2,4-D(也称2,4-滴或2,4-D酸)。2,4-D可作为生长刺激素,2,4-D钠盐、胺盐及酯类具有高度选择性和内吸作用的除草性能,可作为除草剂。合成2,4-D有先氯化和后氯化两种方法,目前国内基本上都采用先氯化法,其工艺依次为苯酚氯化制备2,4-二氯苯酚、2,4-二氯苯酚精制、酚钠盐制备、氯乙酸钠盐制备、缩合、酸化、干燥及废水处理。分别对各部分工艺进行了简单叙述,并结合国内外文献对生产工艺研究和进展进行了介绍。提出了目前2,4-D生产工艺中最迫切需要解决的问题和研究方向。 展开更多
关键词 2 4-二氯苯氧乙酸钠 2 4-d 氯化 缩合
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Microstructure and compression properties of fine Al2O3 particles dispersion strengthened molybdenum alloy 被引量:5
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作者 Tie-long SUN Liu-jie XU +4 位作者 Shi-zhong WEI Kun-ming PAN Wu-hui LI Yu-cheng ZHOU Zhi-min HUANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第12期3307-3321,共15页
The Mo alloys reinforced by Al2O3 particles were fabricated by hydrothermal synthesis and powder metallurgy. The microstructures of Mo-Al2O3 alloys were studied by using XRD, SEM and TEM. The results show that Al2O3 p... The Mo alloys reinforced by Al2O3 particles were fabricated by hydrothermal synthesis and powder metallurgy. The microstructures of Mo-Al2O3 alloys were studied by using XRD, SEM and TEM. The results show that Al2O3 particles, existing as a stable hexagonal phase(α-Al2O3), are uniformly dispersed in Mo matrix. The ultrafine α-Al2O3 particles remarkably refine grain size and increase dislocation density of Mo alloys. Moreover, a good interfacial bonding zone between α-Al2O3 and Mo grain is obtained. The crystallographic orientations of the interface of the Al2O3 particles and Mo matrix are [111]a-Al2O3//[111]Mo and(112)a-Al2O3//(0 11)Mo. Due to the effect of secondary phase and dislocation strengthening, the yield strength of Mo-2.0 vol.%Al2O3 alloy annealed at 1200 ℃ is approximately 56.0% higher than that of pure Mo. The results confirm that the addition of Al2O3 particles is a promising method to improve the mechanical properties of Mo alloys. 展开更多
关键词 Mo−Al2O3 alloys hydrothermal synthesis interface compression test dispersion strengthening
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子宫内膜癌患者血清NRP-2 VEGF-C和VEGF-D水平与其转移的相关性研究 被引量:1
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作者 邹歌 赵楠楠 +4 位作者 董建新 周剑利 袁金灵 高杰 郭艳娟 《安徽医学》 2025年第1期54-57,共4页
目的 探究子宫内膜癌(EC)患者血清神经菌毛蛋白-2(NRP-2)、血管内皮生长因子C(VEGF-C)和血管内皮生长因子D(VEGF-D)水平与其转移的关系。方法 选取2020年5月至2024年2月华北理工大学附属医院收治的147例EC患者为研究对象,以病理结果为... 目的 探究子宫内膜癌(EC)患者血清神经菌毛蛋白-2(NRP-2)、血管内皮生长因子C(VEGF-C)和血管内皮生长因子D(VEGF-D)水平与其转移的关系。方法 选取2020年5月至2024年2月华北理工大学附属医院收治的147例EC患者为研究对象,以病理结果为判定标准,根据癌细胞是否发生转移分为转移组(52例)和未转移组(95例),选取46例同期健康体检者为对照组,比较3组对象NRP-2、VEGF-C和VEGF-D水平,并分析与EC转移的关系。结果 转移组和未转移组的NRP-2、VEGF-C和VEGF-D水平均高于对照组,差异有统计学意义(P<0.05)。转移组的NRP-2、VEGF-C和VEGF-D水平均高于未转移组,差异有统计学意义(P<0.05)。转移组的内膜样癌占比、病理G1级占比和浸润深度≤1/2肌层占比均低于未转移组,差异有统计学意义(P<0.05)。非内膜样癌(OR=3.376,95%CI:1.037~10.995,P=0.043)、病理G2(OR=19.426,95%CI:2.895~130.338,P=0.002)或G3级(OR=11.311,95%CI:1.842~69.453,P=0.009)、浸润深度>1/2肌层(OR=10.683,95%CI:2.889~39.512,P<0.001)和高NRP-2水平(OR=1.847,95%CI:1.452~2.349,P<0.001)均是EC转移的独立危险因素。限制性立方样条分析结果显示,NRP-2与EC转移主要呈线性关系(P<0.001)。当NRP-2<17.35μg/L时,EC转移风险低;当NRP-2>17.35μg/L时,EC转移风险高。结论 子宫内膜癌患者血清NRP-2水平高与其转移有关,NRP-2水平升高是EC转移的独立预测因子。 展开更多
关键词 子宫内膜癌 神经菌毛蛋白-2 血管内皮生长因子-C 血管内皮生长因子-d 转移
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纳米TiO_(2)对Al_(2)O_(3)陶瓷烧结特性的影响
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作者 陈友梅 李镒成 +5 位作者 何婷 刘应寿 黎阳 肖汉宁 袁谋云 张伟群 《硅酸盐通报》 北大核心 2026年第1期256-263,共8页
以煅烧α-Al_(2)O_(3)粉体为原料、纳米TiO_(2)为烧结助剂、羧甲基纤维素为成型黏结剂,采用模压成型-常压烧结制备了Al_(2)O_(3)陶瓷,研究了烧结温度及纳米TiO_(2)添加量对Al_(2)O_(3)陶瓷微观形貌、线收缩率、物相结构、体积密度、孔... 以煅烧α-Al_(2)O_(3)粉体为原料、纳米TiO_(2)为烧结助剂、羧甲基纤维素为成型黏结剂,采用模压成型-常压烧结制备了Al_(2)O_(3)陶瓷,研究了烧结温度及纳米TiO_(2)添加量对Al_(2)O_(3)陶瓷微观形貌、线收缩率、物相结构、体积密度、孔隙率、抗折强度和白度的影响,评估了烧结特性。结果表明,添加适量纳米TiO_(2)能够显著提高Al_(2)O_(3)陶瓷的烧结性能,而过量纳米TiO_(2)会造成Al_(2)O_(3)晶粒异常长大,进而导致收缩率和体积密度降低、孔隙率增大。当纳米TiO_(2)添加量为0.7%(质量分数)、烧结温度为1 500℃时,Al_(2)O_(3)陶瓷性能较为优异,其抗折强度达到最大值,为(188.89±5.87) MPa,体积密度、孔隙率和白度分别为3.45 g·cm^(-3)、7.78%和76.6。 展开更多
关键词 Al_(2)O_(3)陶瓷 纳米TiO_(2) 模压成型 烧结温度 烧结助剂
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Block sparse compressed sensing with frames:Null space property and l_(2)/l_(q)(0
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作者 WU Fengong ZHONG Penghong QIN Yuehai 《中山大学学报(自然科学版)(中英文)》 北大核心 2025年第3期173-182,共10页
This paper explores the recovery of block sparse signals in frame-based settings using the l_(2)/l_(q)-synthesis technique(0<q≤1).We propose a new null space property,referred to as block D-NSP_(q),which is based ... This paper explores the recovery of block sparse signals in frame-based settings using the l_(2)/l_(q)-synthesis technique(0<q≤1).We propose a new null space property,referred to as block D-NSP_(q),which is based on the dictionary D.We establish that matrices adhering to the block D-NSP_(q)condition are both necessary and sufficient for the exact recovery of block sparse signals via l_(2)/l_(q)-synthesis.Additionally,this condition is essential for the stable recovery of signals that are block-compressible with respect to D.This D-NSP_(q)property is identified as the first complete condition for successful signal recovery using l_(2)/l_(q)-synthesis.Furthermore,we assess the theoretical efficacy of the l2/lq-synthesis method under conditions of measurement noise. 展开更多
关键词 compressed sensing block sparse l2/lq-synthesis method null space property
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CO_(2)/O_(2)环境下氨-柴融合燃料压缩着火机理研究
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作者 张青山 刘永峰 +1 位作者 宋金瓯 潘家营 《内燃机学报》 北大核心 2026年第1期1-9,共9页
基于快速压缩机(RCM)试验平台研究氨-柴融合燃料在CO_(2)/O_(2)环境下的压缩着火特性,提出新的氨-柴融合燃料(ADFF)模型,该模型考虑高体积分数CO_(2)对燃烧反应速率的影响,以正庚烷(n-C_(7)H_(16))作为柴油表征燃料,构建了包含149个组分... 基于快速压缩机(RCM)试验平台研究氨-柴融合燃料在CO_(2)/O_(2)环境下的压缩着火特性,提出新的氨-柴融合燃料(ADFF)模型,该模型考虑高体积分数CO_(2)对燃烧反应速率的影响,以正庚烷(n-C_(7)H_(16))作为柴油表征燃料,构建了包含149个组分和719个反应的氨-柴融合表征燃料机理,结合仿真软件对融合燃料的压缩着火过程进行了计算;搭建了RCM试验平台,对能量占比为10%氨+90%柴油的融合燃料在CO_(2)体积分数为35%~47%条件下进行了试验.结果表明:ADFF模型可以较准确计算氨-柴融合燃料在不同CO_(2)氛围下压缩着火的着火延迟时间,其最大误差为6.02%,最小误差为2.49%;对CO_(2)体积分数变化敏感度最大的着火反应是正庚烷和氨的热解反应,分别下降了48.1%和22.7%;发现高体积分数CO_(2)环境下存在第三体效应,在CO_(2)体积分数为35%~47%内呈现小幅度促进燃烧反应的效果,但高体积分数CO_(2)对氨-柴融合燃料的整体燃烧进程仍表现为抑制的趋势. 展开更多
关键词 快速压缩机 氨-柴融合燃料 CO_(2)/O_(2)环境 着火延迟时间
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WELL-POSEDNESS OF 2-D HYPERBOLIC VISCOUS CAHN-HILLIARD EQUATION
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作者 Siyan GUO Jiangbo HAN Runzhang XU 《Acta Mathematica Scientia》 2025年第4期1438-1470,共33页
In this paper,we consider the initial boundary value problem for the 2-D hyperbolic viscous Cahn-Hilliard equation.Firstly,we prove the existence and uniqueness of the local solution by the Galerkin method and contrac... In this paper,we consider the initial boundary value problem for the 2-D hyperbolic viscous Cahn-Hilliard equation.Firstly,we prove the existence and uniqueness of the local solution by the Galerkin method and contraction mapping principle.Then,using the potential well theory,we study the global well-posedness of the solution with initial data at different levels of initial energy,i.e.,subcritical initial energy,critical initial energy and arbitrary positive initial energy.For subcritical initial energy,we prove the global existence,asymptotic behavior and finite time blowup of the solution.Moreover,we extend these results to the critical initial energy using the scaling technique.For arbitrary positive initial energy,including the sup-critical initial energy,we obtain the sufficient conditions for finite time blow-up of the solution.As a further study for estimating the blowup time,we give a unified expression of the lower bound of blowup time for all three initial energy levels and estimate the upper bound of blowup time for subcritical and critical initial energy. 展开更多
关键词 2-d hyperbolic viscous Cahn-Hilliard equation global existence finite time blow up exponential decay
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组织Spondin-2、MUC-1、Cath-D联合检测对宫颈癌术后复发的预测价值
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作者 董洁 李文凯 +3 位作者 王成静 刘畅 孔雪 刘玉珍 《临床误诊误治》 2025年第14期89-93,共5页
目的探讨组织脊椎蛋白-2(Spondin-2)、黏蛋白-1(MUC-1)、组织蛋白酶-D(Cath-D)联合检测对宫颈癌术后复发的预测价值。方法选取2019年4月至2021年4月就诊的235例宫颈癌手术患者,根据术后3年复发情况分为复发组和未复发组。统计并比较两... 目的探讨组织脊椎蛋白-2(Spondin-2)、黏蛋白-1(MUC-1)、组织蛋白酶-D(Cath-D)联合检测对宫颈癌术后复发的预测价值。方法选取2019年4月至2021年4月就诊的235例宫颈癌手术患者,根据术后3年复发情况分为复发组和未复发组。统计并比较两组人口学特征、临床病理特征及组织Spondin-2、MUC-1、Cath-D mRNA表达,采用Spearman相关分析临床病理特征与组织Spondin-2、MUC-1、Cath-D mRNA表达的相关性,采用多因素logistic回归分析宫颈癌术后复发的影响因素,采用受试者工作特征(ROC)曲线分析组织Spondin-2、MUC-1、Cath-D mRNA表达预测宫颈癌术后复发的价值。结果两组肿瘤直径、FIGO分期、分化程度、人乳头瘤病毒(HPV)感染、盆腔淋巴结转移比较存在显著差异(P<0.01)。复发组组织Spondin-2、MUC-1、Cath-D mRNA表达均高于未复发组(P<0.01)。Spearman相关分析显示,宫颈癌手术患者组织Spondin-2、MUC-1、Cath-D mRNA表达与肿瘤直径、FIGO分期、分化程度、HPV感染、盆腔淋巴结转移呈正相关(P<0.01)。多因素logistic回归分析显示,组织Spondin-2、MUC-1、Cath-D mRNA表达及HPV感染是宫颈癌术后复发的影响因素(P<0.01)。ROC曲线显示,组织Spondin-2、MUC-1、Cath-D mRNA表达联合预测宫颈癌术后复发的曲线下面积高于单一指标预测。结论组织Spondin-2、MUC-1、Cath-D联合检测对宫颈癌术后复发有较高的预测价值,利于临床早期预测宫颈癌术后复发、制订相应干预方案。 展开更多
关键词 宫颈肿瘤 手术治疗 复发 脊椎蛋白-2 黏蛋白-1 组织蛋白酶-d 相关性 预测价值
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Study on Performance and Emission Characteristics of a Compression Ignition Engine Fueled with Diesel-2 Ethoxy Ethyl Acetate Blends
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作者 B. Deepanraj P. Lawrence +3 位作者 M. Kannan V. Nadanakumar S. Santhanakrishnan R. Senthil 《Engineering(科研)》 2011年第11期1132-1136,共5页
Diesel engines are the major contributors of various types of air polluting gases like carbon monoxide, oxides of nitrogen, smoke, etc. Improvement of fuel properties is essential for suppression of Diesel pollutant e... Diesel engines are the major contributors of various types of air polluting gases like carbon monoxide, oxides of nitrogen, smoke, etc. Improvement of fuel properties is essential for suppression of Diesel pollutant emissions along with the optimization of design factors and after treatment equipment. Studies conducted in the past have shown that a significant reduction were obtained in the emissions using oxygenates. This paper investigates the performance and emission characteristics of a direct injection Diesel engine fueled with 2 Ethoxy Ethyl Acetate (EEA) blends. Different fuel blends which contain 5%, 10% and 15% of EEA were prepared and the effect of these blends on performance and emissions were studied on a single cylinder direct injection Diesel engine. The blends were tested under different load conditions and the result showed that EEA blended fuels improves the performance of the engine and reduce the emission level significantly. 展开更多
关键词 2 Ethoxy ETHYL ACETATE DIESEL Performance Emission compression IGNITION Engine
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工作井数对含水层压缩CO_(2)储能系统季节性运行的影响
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作者 赖杨志 李毅 黄乐清 《吉首大学学报(自然科学版)》 2026年第1期55-66,共12页
为了明确工作井数对含水层压缩CO_(2)储能系统运行性能的影响,建立3个不同工作井数(9,5,3)的井群-储气库三维数值模型,运用T2WELL数值模拟软件,探究了储能系统在不同工作井条件下季节性循环运行情况.结果表明,当工作井数由9减少到3时,... 为了明确工作井数对含水层压缩CO_(2)储能系统运行性能的影响,建立3个不同工作井数(9,5,3)的井群-储气库三维数值模型,运用T2WELL数值模拟软件,探究了储能系统在不同工作井条件下季节性循环运行情况.结果表明,当工作井数由9减少到3时,中心井井口最大压力由17.42 MPa增大到18.23 MPa,最高温度由59.21℃上升到60.18℃,储能系统最高能量效率由1.028 55下降到1.027 74.这说明,工作井数会显著影响井筒-地层系统内的CO_(2)运移规律及压力/温度传递过程,因而在实际工程中,可通过增设工作井的方式来降低储能系统循环过程中注入阶段的压力/温度,进而提升储能系统的能量效率. 展开更多
关键词 工作井 含水层压缩CO_(2)储能系统 季节性循环 数值模拟
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血清D-D、Runx2、CTX与骨质疏松性椎体压缩骨折患者PKP手术预后的关系
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作者 冯红卫 李超 及宁 《临床和实验医学杂志》 2025年第18期1931-1934,共4页
目的探讨血清D-二聚体(D-D)、核心结合因子2(Runx2)、I型胶原交联羧基末端肽(CTX)与骨质疏松性椎体压缩骨折(OVCF)患者经皮椎体后凸成形术(PKP)手术预后的关系。方法回顾性分析2022年1月至2024年3月沧州市人民医院收治的82例OVCF患者的... 目的探讨血清D-二聚体(D-D)、核心结合因子2(Runx2)、I型胶原交联羧基末端肽(CTX)与骨质疏松性椎体压缩骨折(OVCF)患者经皮椎体后凸成形术(PKP)手术预后的关系。方法回顾性分析2022年1月至2024年3月沧州市人民医院收治的82例OVCF患者的临床资料。患者行PKP手术后进行3个月随访,骨折愈合延迟患者11例纳入愈合不良组,骨折正常愈合患者71例纳入愈合良好组。收集、比较两组临床资料;分析OVCF患者PKP手术预后不良的影响因素;采用受试者操作特征(ROC)曲线分析D-D、Runx2、CTX预测OVCF患者PKP手术预后不良的价值。结果两组在性别、年龄、吸烟、饮酒、高血压及其他基础疾病、骨质疏松病程、骨折部位、骨水泥用量方面比较,差异均无统计学意义(P>0.05);愈合不良组糖尿病患者占比、有椎体裂隙征患者占比、D-D、CTX水平分别为36.36%、63.64%、(3.59±0.86)mg/L、(681.43±156.37)pg/mL,均高于愈合良好组[8.45%、25.35%、(0.92±0.26)mg/L、(355.72±91.06)pg/mL],Runx2水平为(0.51±0.04)μg/L,低于愈合良好组[(0.65±0.07)μg/L],差异均有统计学意义(P<0.05)。多因素Logistic回归分析显示,糖尿病、椎体裂隙征、D-D、CTX均是OVCF患者PKP手术预后不良的独立危险因素(P<0.05),Runx2是OVCF患者PKP手术预后不良的独立保护因素(P<0.05)。ROC曲线分析结果显示,D-D、Runx2、CTX单独及联合预测OVCF患者PKP手术预后不良的曲线下面积分别为0.786、0.824、0.850、0.928,敏感度分别为0.727、0.727、0.818、0.909,特异度分别为0.676、0.831、0.648、0.803(均P<0.05)。结论OVCF患者PKP手术预后与糖尿病、椎体裂隙征、D-D、Runx2、CTX有关,血清D-D及CTX升高、Runx2下降在患者骨折愈合延迟中有一定预测价值。 展开更多
关键词 骨质疏松性椎体压缩骨折 D-二聚体 核心结合因子2 I型胶原交联羧基末端肽 骨折愈合
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补气与平行压缩CO_(2)跨临界制冷系统的性能对比分析
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作者 吕捷 张文婷 杨启超 《制冷与空调》 2026年第2期75-83,共9页
文章针对补气与平行压缩CO_(2)跨临界制冷系统建立热力学分析数学模型,对比分析相对中间压力、气冷器出口温度和蒸发温度等工况参数对经济器、闪发器、经济器平行压缩和闪发平行压缩CO_(2)跨临界制冷系统的性能影响规律。研究表明:在不... 文章针对补气与平行压缩CO_(2)跨临界制冷系统建立热力学分析数学模型,对比分析相对中间压力、气冷器出口温度和蒸发温度等工况参数对经济器、闪发器、经济器平行压缩和闪发平行压缩CO_(2)跨临界制冷系统的性能影响规律。研究表明:在不同的气冷器出口温度和蒸发温度下,4个系统均存在最佳的相对中间压力和最佳排气压力。补气系统比平行压缩系统有更高的COP值,更低的压缩机功耗和排气温度,而补气系统中的带闪发器的跨临界CO_(2)制冷系统性能最佳。 展开更多
关键词 跨临界CO_(2)制冷系统 经济器 平行压缩 热力学分析 性能系数
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外源2,4-D对大豆再生过程的影响 被引量:8
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作者 李思楠 张超 +7 位作者 马彦龙 姜成涛 王玲爽 王传奇 于以成 李文滨 苏安玉 武小霞 《基因组学与应用生物学》 CAS CSCD 北大核心 2015年第6期1324-1332,共9页
为了寻找与大豆再生直接相关的基因,提高大豆转化率,解决大豆再生和转化困难的问题,以再生较好的东农50、再生较差绥农14两个大豆品种为材料,设计不同2,4-D浓度处理及不同取材时间,测定与大豆再生相关的IAA、SOD、PAL以及再生率指标。... 为了寻找与大豆再生直接相关的基因,提高大豆转化率,解决大豆再生和转化困难的问题,以再生较好的东农50、再生较差绥农14两个大豆品种为材料,设计不同2,4-D浓度处理及不同取材时间,测定与大豆再生相关的IAA、SOD、PAL以及再生率指标。结果表明:东农50在2,4-D浓度为8 mg/L、12 h处理下IAA浓度最大,比对照增加了76.9%,在2,4-D浓度为4 mg/L、4 h处理下SOD酶活性增幅最高,比对照增加了50.9%,在2,4-D浓度为4 m/L、8 h处理下PAL酶活性最高,比对照增加了76.4%;绥农14在2,4-D浓度为8 mg/L、2 h处理下IAA浓度最大,比对照增加97.1%,在2,4-D浓度为4 mg/L、12 h处理下SOD酶活性最高,比对照增加23.8%,在2,4-D浓度为2 mg/L、4 h处理下PAL酶活性最高,比对照增加53.9%。东农50和绥农14均在2,4-D浓度为4 mg/L时再生率最高,分别为87.6%和79.5%。依照该实验结果进行取材,应用转录组测序技术挖掘与大豆再生直接相关的基因,解释再生作用机理,解决大豆再生和转化受基因型限制的难题,为大豆基因功能研究及转化率的提高提供了理论和技术支持。 展开更多
关键词 大豆 再生 2 4-d IAA SOD PAL
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