Herein, we assess the129I transmutation capability of a 2250-MWt single-fluid double-zone thorium molten salt reactor(SD-TMSR) by considering two methods. One is realized by loading an appropriate amount of129I before...Herein, we assess the129I transmutation capability of a 2250-MWt single-fluid double-zone thorium molten salt reactor(SD-TMSR) by considering two methods. One is realized by loading an appropriate amount of129I before the startup of the reactor, and the amount of129I during operation is kept constant by online feeding129I.The other adopts only an initial loading of129I before startup, and no other129I is fed online during operation.The investigation first focuses on the effect of the loading of I on the Th-233U isobreeding performance. The results indicate that a233U isobreeding mode can be achieved for both scenarios for a 60-year operation when the initial molar proportion of LiI is maintained within 0.40% and 0.87%, respectively. Then, the transmutation performances for the two scenarios are compared by changing the amount of injected iodine into the core. It is found that the scenario that adopts an initial loading of129I shows a slightly better transmutation performance in comparison with the scenario that adopts online feeding of129I when the net233U productions for the two scenarios are kept equal. The initial loading of129I scenario with LiI = 0.87% molar proportion is recommended for129I transmutation in the SD-TMSR,and can transmute 1.88 t of129I in the233U isobreeding mode over 60 years.展开更多
本研究建立了AMS(Accelerator mass spectrum,加速器质谱)测定海水中129 I的气载分离制样方法:对加入载体的海水样品进行氧化还原处理,在加热的条件下将生成的单质碘吹出,并使用吸收装置吸收,后经阴离子交换树脂富集纯化,最后生成用于AM...本研究建立了AMS(Accelerator mass spectrum,加速器质谱)测定海水中129 I的气载分离制样方法:对加入载体的海水样品进行氧化还原处理,在加热的条件下将生成的单质碘吹出,并使用吸收装置吸收,后经阴离子交换树脂富集纯化,最后生成用于AMS分析的AgI沉淀,本方法全程回收率50%~70%,在相对密闭的体系中进行,减少了碘的损失,相对于萃取-反萃取的制样方法具有可操作性强,避免有机试剂使用等优点,可用于固态、液态和气态样品中129 I的AMS分析制样。展开更多
目的 分析创伤性颅脑损伤血清miR-31-5p、miR-129-5p水平及其与神经功能的关系。方法 回顾性选取2022年8月—2025年8月东南大学附属徐州市中心医院收治的创伤性颅脑损伤患者169例,根据格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分将...目的 分析创伤性颅脑损伤血清miR-31-5p、miR-129-5p水平及其与神经功能的关系。方法 回顾性选取2022年8月—2025年8月东南大学附属徐州市中心医院收治的创伤性颅脑损伤患者169例,根据格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分将患者分为轻型组(n=64)、中型组(n=54)、重型组(n=51)。另选同期东南大学附属徐州市中心医院体检的健康者100例为对照组。比较所有受试者血清miR-31-5p、miR-129-5p水平、美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分。采用Pearson相关分析血清miR-31-5p、miR-129-5p水平与NIHSS评分的相关性,采用受试者工作特征(receiver operating characteristic,ROC)曲线分析血清miR-31-5p、miR-129-5p水平对创伤性颅脑损伤患者发生神经功能缺损的诊断价值。结果 重型组、中型组、轻型组血清miR-31-5p水平、NIHSS评分均高于对照组,血清miR-129-5p水平均低于对照组,重型组、中型组血清miR-31-5p水平、NIHSS评分均高于轻型组,血清miR-129-5p水平均低于轻型组,重型组血清miR-31-5p水平、NIHSS评分均高于中型组,血清miR-129-5p水平低于中型组(P<0.05)。血清miR-31-5p水平与NIHSS评分呈正相关(r=0.666,P<0.05),血清miR-129-5p水平与NIHSS评分呈负相关(r=-0.715,P<0.05)。ROC结果显示,血清miR-31-5p、miR-129-5p水平联合诊断创伤性颅脑损伤患者神经功能缺损的敏感度为99.3%,特异度为92.9%,AUC为0.951,预测价值较高。结论 血清miR-31-5p水平升高、miR-129-5p水平降低与创伤性颅脑损伤患者神经功能缺损程度密切相关,二者联合检测对评估神经功能缺损具有较高预测价值。展开更多
基金supported by the Chinese TMSR Strategic Pioneer Science and Technology Project(No.XDA02010000)the Frontier Science Key Program of the Chinese Academy of Sciences(No.QYZDY-SSW-JSC016)
文摘Herein, we assess the129I transmutation capability of a 2250-MWt single-fluid double-zone thorium molten salt reactor(SD-TMSR) by considering two methods. One is realized by loading an appropriate amount of129I before the startup of the reactor, and the amount of129I during operation is kept constant by online feeding129I.The other adopts only an initial loading of129I before startup, and no other129I is fed online during operation.The investigation first focuses on the effect of the loading of I on the Th-233U isobreeding performance. The results indicate that a233U isobreeding mode can be achieved for both scenarios for a 60-year operation when the initial molar proportion of LiI is maintained within 0.40% and 0.87%, respectively. Then, the transmutation performances for the two scenarios are compared by changing the amount of injected iodine into the core. It is found that the scenario that adopts an initial loading of129I shows a slightly better transmutation performance in comparison with the scenario that adopts online feeding of129I when the net233U productions for the two scenarios are kept equal. The initial loading of129I scenario with LiI = 0.87% molar proportion is recommended for129I transmutation in the SD-TMSR,and can transmute 1.88 t of129I in the233U isobreeding mode over 60 years.
文摘本研究建立了AMS(Accelerator mass spectrum,加速器质谱)测定海水中129 I的气载分离制样方法:对加入载体的海水样品进行氧化还原处理,在加热的条件下将生成的单质碘吹出,并使用吸收装置吸收,后经阴离子交换树脂富集纯化,最后生成用于AMS分析的AgI沉淀,本方法全程回收率50%~70%,在相对密闭的体系中进行,减少了碘的损失,相对于萃取-反萃取的制样方法具有可操作性强,避免有机试剂使用等优点,可用于固态、液态和气态样品中129 I的AMS分析制样。
文摘目的 分析创伤性颅脑损伤血清miR-31-5p、miR-129-5p水平及其与神经功能的关系。方法 回顾性选取2022年8月—2025年8月东南大学附属徐州市中心医院收治的创伤性颅脑损伤患者169例,根据格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分将患者分为轻型组(n=64)、中型组(n=54)、重型组(n=51)。另选同期东南大学附属徐州市中心医院体检的健康者100例为对照组。比较所有受试者血清miR-31-5p、miR-129-5p水平、美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分。采用Pearson相关分析血清miR-31-5p、miR-129-5p水平与NIHSS评分的相关性,采用受试者工作特征(receiver operating characteristic,ROC)曲线分析血清miR-31-5p、miR-129-5p水平对创伤性颅脑损伤患者发生神经功能缺损的诊断价值。结果 重型组、中型组、轻型组血清miR-31-5p水平、NIHSS评分均高于对照组,血清miR-129-5p水平均低于对照组,重型组、中型组血清miR-31-5p水平、NIHSS评分均高于轻型组,血清miR-129-5p水平均低于轻型组,重型组血清miR-31-5p水平、NIHSS评分均高于中型组,血清miR-129-5p水平低于中型组(P<0.05)。血清miR-31-5p水平与NIHSS评分呈正相关(r=0.666,P<0.05),血清miR-129-5p水平与NIHSS评分呈负相关(r=-0.715,P<0.05)。ROC结果显示,血清miR-31-5p、miR-129-5p水平联合诊断创伤性颅脑损伤患者神经功能缺损的敏感度为99.3%,特异度为92.9%,AUC为0.951,预测价值较高。结论 血清miR-31-5p水平升高、miR-129-5p水平降低与创伤性颅脑损伤患者神经功能缺损程度密切相关,二者联合检测对评估神经功能缺损具有较高预测价值。
