ThMn_(12)-type iron-rich rare-earth permanent magnetic materials have garnered significant attention due to their exceptional intrinsic magnetic properties.However,challenges such as the metastable nature of the ThMn1...ThMn_(12)-type iron-rich rare-earth permanent magnetic materials have garnered significant attention due to their exceptional intrinsic magnetic properties.However,challenges such as the metastable nature of the ThMn12-type phase,excessively small single-domain grain size,and complex fabrication processes have hindered the achievement of high phase purity,uniform microstructure,and desirable extrinsic performance.In this study,we directly synthesized ThMn_(12)-type Sm_(0.8)Zr_(0.2)Fe_(11)SiB_(x)(x=0-0.2)ribbon magnets via boron doping combined with a one-step rapid solidification method.This approach not only simplifies the fabrication process but also enhances phase stability and achieves a uniform microstructure with high ThMn12-type phase purity.By optimizing the boron content and cooling rate,the resulting magnets exhibit a coercivity(H_(c))of 6222 Oe,a remanence(M_(r))of 80 emu/g,and a remanence ratio(M_(r)/M_(s))of 0.71.This work demonstrates a streamlined approach to producing high-performance ThMn12-type magnets and provides insights into their practical application potential.展开更多
目的建立孕早期产前筛查孕妇血清解整合素金属蛋白酶12分泌型(a disintegrin and metalloprotease,ADAM12-S)中位数倍数的校正方法。方法随机选择2008年在本中心自愿参加孕早期唐氏综合征(DS)产前筛查并经随访证实分娩健康儿的孕妇孕8...目的建立孕早期产前筛查孕妇血清解整合素金属蛋白酶12分泌型(a disintegrin and metalloprotease,ADAM12-S)中位数倍数的校正方法。方法随机选择2008年在本中心自愿参加孕早期唐氏综合征(DS)产前筛查并经随访证实分娩健康儿的孕妇孕8～13周血清样本577份,用时间分辨荧光免疫分析法检测血清ADAM12-S浓度。用SPSS 15.0软件构建ADAM12-S与孕龄间的回归关系,选最优模型计算中位浓度,得到ADAM12-S中位数倍数(multiple of the median,MoM)值。探讨MoM值与体重的关系,选取最优模型求出经体重调整后的MoM值。将ADAM12-S初始浓度与消除孕周和体重影响校正后的最终MoM值进行曲线拟合,选取最优模型最终得到ADAM12-S初始浓度与校正后MoM值的关系方程。结果 ADAM12-S中位数(Y)与孕周(t)呈正相关,经s曲线模型拟合后的中位数方程为:Y=e8.412-24.534/t;ADAM12-S MoM值中位数(Y)与体重中位数(z)存在负相关,经指数模型拟合后的方程为:Y=1.603*e-0.009*z;ADAM12-S初始浓度(X)与孕周和体重校正后的最终MoM值(Y)的关系方程为Y=0.036*X0.552。结论 ADAM12-S初始浓度与最终MoM值的关系方程的建立,对临床开展ADAM12-S筛查DS妊娠的研究有重要意义。展开更多
基金Project supported by the National Key R&D Program of China(Grant Nos.2021YFB3500300 and 2023YFB3507000)the Scientific Research Foundation of the High Education Institutions for Distinguished Young Scholars in Anhui Province(Grant No.2022AH020012)+1 种基金partially supported by the Innovation Project for Overseas Researcher in Anhui Province(Grant No.2022LCX004)the facilities at the Center of Free Electron Laser&High Magnetic Field(FEL&HMF)in Anhui University。
文摘ThMn_(12)-type iron-rich rare-earth permanent magnetic materials have garnered significant attention due to their exceptional intrinsic magnetic properties.However,challenges such as the metastable nature of the ThMn12-type phase,excessively small single-domain grain size,and complex fabrication processes have hindered the achievement of high phase purity,uniform microstructure,and desirable extrinsic performance.In this study,we directly synthesized ThMn_(12)-type Sm_(0.8)Zr_(0.2)Fe_(11)SiB_(x)(x=0-0.2)ribbon magnets via boron doping combined with a one-step rapid solidification method.This approach not only simplifies the fabrication process but also enhances phase stability and achieves a uniform microstructure with high ThMn12-type phase purity.By optimizing the boron content and cooling rate,the resulting magnets exhibit a coercivity(H_(c))of 6222 Oe,a remanence(M_(r))of 80 emu/g,and a remanence ratio(M_(r)/M_(s))of 0.71.This work demonstrates a streamlined approach to producing high-performance ThMn12-type magnets and provides insights into their practical application potential.
文摘目的建立孕早期产前筛查孕妇血清解整合素金属蛋白酶12分泌型(a disintegrin and metalloprotease,ADAM12-S)中位数倍数的校正方法。方法随机选择2008年在本中心自愿参加孕早期唐氏综合征(DS)产前筛查并经随访证实分娩健康儿的孕妇孕8～13周血清样本577份,用时间分辨荧光免疫分析法检测血清ADAM12-S浓度。用SPSS 15.0软件构建ADAM12-S与孕龄间的回归关系,选最优模型计算中位浓度,得到ADAM12-S中位数倍数(multiple of the median,MoM)值。探讨MoM值与体重的关系,选取最优模型求出经体重调整后的MoM值。将ADAM12-S初始浓度与消除孕周和体重影响校正后的最终MoM值进行曲线拟合,选取最优模型最终得到ADAM12-S初始浓度与校正后MoM值的关系方程。结果 ADAM12-S中位数(Y)与孕周(t)呈正相关,经s曲线模型拟合后的中位数方程为:Y=e8.412-24.534/t;ADAM12-S MoM值中位数(Y)与体重中位数(z)存在负相关,经指数模型拟合后的方程为:Y=1.603*e-0.009*z;ADAM12-S初始浓度(X)与孕周和体重校正后的最终MoM值(Y)的关系方程为Y=0.036*X0.552。结论 ADAM12-S初始浓度与最终MoM值的关系方程的建立,对临床开展ADAM12-S筛查DS妊娠的研究有重要意义。
