In DSP-based SerDes application,it is essential for AFE to implement a pre-ADC equalization to provide a better sig-nal for ADC and DSP.To meet the various equalization requirements of different channel and transmitte...In DSP-based SerDes application,it is essential for AFE to implement a pre-ADC equalization to provide a better sig-nal for ADC and DSP.To meet the various equalization requirements of different channel and transmitter configurations,this paper presents a 112 Gbps DSP-Based PAM4 SerDes receiver with a wide band equalization tuning AFE.The AFE is realized by implementing source degeneration transconductance,feedforward high-pass branch and inductive feedback peaking TIA.The AFE offers a flexible equalization gain tuning of up to 17.5 dB at Nyquist frequency without affecting the DC gain.With the pro-posed AFE,the receiver demonstrates eye opening after digital FIR equalization and achieves 6×10^(-9) BER with a 29.6 dB inser-tion loss channel.展开更多
目的探讨凋亡抑制基因Survivin和GW112在反流性食管炎、Barrett食管及食管腺癌中的表达及其意义。方法采用SYBR Green I荧光定量RT-PCR方法检测反流性食管炎、Barrett食管、食管腺癌黏膜组织中SurvivinmRNA和GW112 mRNA的表达。结果 GW...目的探讨凋亡抑制基因Survivin和GW112在反流性食管炎、Barrett食管及食管腺癌中的表达及其意义。方法采用SYBR Green I荧光定量RT-PCR方法检测反流性食管炎、Barrett食管、食管腺癌黏膜组织中SurvivinmRNA和GW112 mRNA的表达。结果 GW112在对照组和反流性食管炎阴性组中呈低水平表达,明显低于反流性食管炎阳性组、Barrett食管组及食管腺癌组的表达(P<0.05),反流性食管炎阳性组、Barrett食管组及食管腺癌组GW112表达水平无明显差异(P>0.05)。Survivin表达水平依正常对照、反流性食管炎阴性、反流性食管炎阳性、Barrett食管、食管腺癌的次序渐进增强,其中反流性食管炎阳性组、Barrett食管与食管腺癌组患者Survivin表达水平明显高于对照组和反流性食管炎阴性组(P<0.05,P<0.01),且3组间亦存在显著性差异(P<0.05,P<0.01)。结论 Survivin和GW112基因的过度表达引起的细胞凋亡抑制在Barrett食管及其腺癌发生、发展过程中起着重要的作用,尤其是Survivin在Barrett食管与食管腺癌的发生、发展最早步骤中可能扮演着更主要的角色。展开更多
基金supported by National Key R&D Program of China No.2022YFB2803401.
文摘In DSP-based SerDes application,it is essential for AFE to implement a pre-ADC equalization to provide a better sig-nal for ADC and DSP.To meet the various equalization requirements of different channel and transmitter configurations,this paper presents a 112 Gbps DSP-Based PAM4 SerDes receiver with a wide band equalization tuning AFE.The AFE is realized by implementing source degeneration transconductance,feedforward high-pass branch and inductive feedback peaking TIA.The AFE offers a flexible equalization gain tuning of up to 17.5 dB at Nyquist frequency without affecting the DC gain.With the pro-posed AFE,the receiver demonstrates eye opening after digital FIR equalization and achieves 6×10^(-9) BER with a 29.6 dB inser-tion loss channel.
