An application of techniques is presented to construct G^(1 )smooth surfaces by using acombination of the rectangular and triangular Bezier patches of degree as low as possible. TheG^(1) smooth surfaces have the local...An application of techniques is presented to construct G^(1 )smooth surfaces by using acombination of the rectangular and triangular Bezier patches of degree as low as possible. TheG^(1) smooth surfaces have the local property and interpolate the given data and inherit thetopology imposed by the given space convex quadrilateral partition and triangulation. The papergeneralizes current approaches for assembling of rectangular and triangular patches.展开更多
The Jiangla'angzong granite in the northern part of the Central Lhasa Terrane is composed of syenogranite and adamellite.LA-ICP-MS zircon U-Pb analyses suggest that syenogranite has a weighted mean 2±6pb/23SU...The Jiangla'angzong granite in the northern part of the Central Lhasa Terrane is composed of syenogranite and adamellite.LA-ICP-MS zircon U-Pb analyses suggest that syenogranite has a weighted mean 2±6pb/23SU age of 86±1 Ma(mean square weighted deviation=0.37),which is in accordance with the muscovite Ar-Ar age(85±1 Ma)of Cu-Au ore-bearing skarns and the zircon U-Pb age(84±1 Ma)of adamellite.This suggests that the Jiangla'angzong magmatism and Cu-Au mineralization events took place during the Late Cretaceous.The granite contains hornblende,biotite,and pyroxene,and does not contain Al-bearing minerals,such as muscovite,cordierite,and garnet.It has high contents of SiO2(65.10-70.91wt%),K20(3.44-5.17wt%),and total K20+Na20(7.13-8.15wt%),and moderate contents of A12Oa(14.14-16.45wt%)and CaO(2.33-4.11wt%),with a Reitman index(δ43)of 2.18 to 2.33,and A/CNK values of 0.88 to 1.02.The P205 contents show a negative correlation with SiO2,whereas Pb contents show a positive correlation with SiO2.Th and Y contents are relatively low and show a negative correlation with the Rb contents.These characteristics suggest that the Jiangla'angzong granite is a high K calc-alkaline metaluminous I-type granite.It is enriched in light rare earth elements(LREE)and large ion lithofile elements(LILE),and depleted in heavy rare earth elements(HREE)and high field strength elements(HFSE),with LREE/HREE ratios of 11.7 to 18.1.The granite has negative Eu anomalies of 0.58 to 0.94 without obvious Ce anomalies(δCe=l.00-1.04).The relatively low initial a7Sr/a6Sr ratios of 0.7106 to 0.7179,positiveε±nt(t)values of 1.0 to 4.1,and two-stage Hf model ages(TDM2)ranging from 889 Ma to 1082 Ma,These geochemical features indicate that the granite derived from a juvenile crust.The(143Nd/144Nd)t values from the Jiangla'angzong granite range from 0.5121 to 0.5123,its eNd(t)values range from-10.17 to-6.10,its(^206pb/^204pb)t values range from 18.683 to 18.746,its(^207pb/^204pb)t values range from 15.695 to 15.700,and its(^208pb/^204pb)t values range from 39.012 to 39.071.These data indicate that the granite was formed by melting of the upper crust with the addition of some mantle materials.We propose that the Jiangla'angzong granite was formed during the post-collision extension of the Qiangtang and Lhasa terranes.展开更多
The excellent thermal stability of magnetic properties of Sm_(2)Co_(17)-based magnets is their most impor-tant feature.However,this stability is reduced when the maximum energy product of Sm_(2)Co_(17)-based magnets i...The excellent thermal stability of magnetic properties of Sm_(2)Co_(17)-based magnets is their most impor-tant feature.However,this stability is reduced when the maximum energy product of Sm_(2)Co_(17)-based magnets is improved,which is mainly determined by the Fe/Cu distribution of the 2:17R cell and 1:5H cell boundary phases.During the demagnetization process,the Cu-rich 1:5H cell boundary phase with a width of 2-15 nm obstructs the motion of the domain walls,yielding coercivity.Herein,we report a micron-scale Cu/Zr-rich and Fe-lean 1:5H-based precipitated phase with a lamellar structure,probably induced by Sm_(2)O_(3) doping.This structure enables the separate regulation of Fe and Cu distribution for Sm_(2)Co_(17)-based magnets with Fe-rich 2:17R cell phases and Cu-rich 1:5H cell boundary phases,consid-erably optimizing the thermal stability of magnetic properties.This discovery can be further developed to produce Sm_(2)Co_(17)-based magnets with high performance and excellent thermal stability of magnetic properties.展开更多
In the western Yangtze Block,widespread Mesoproterozoic to Neoproterozoic rocks are the key to understanding the Precambrian tectonic-magmatic evolution of the region.However,their petrogenesis and tectonic setting ar...In the western Yangtze Block,widespread Mesoproterozoic to Neoproterozoic rocks are the key to understanding the Precambrian tectonic-magmatic evolution of the region.However,their petrogenesis and tectonic setting are still controversial.In this paper,zircon U-Pb ages,Sm-Nd isotopic and whole-rock geochemical data are reported from selected fresh samples in the southern Dechang county,southwestern China,in order to constrain their emplacement age and magma source,as well as their petrogenesis and tectonic setting.They are mainly composed of biotite monzogranite,monzonitic granite,biotite granodiorites,and quartz diorite.Two ages of 1055±43 Ma and 837.6±3.8 Ma were obtained through zircon U-Pb dating by LA-ICP-MS and LA-MC-ICP-MS,respectively.According to their major element compositions,the Grenville-age granites are peraluminous calc-alkaline series calcic S-type granite.In contrast,the mid-Neoproterozoic granites are metaluminous calc-aikaline series alkalic I-type granite.Furthermore,the S-type granites are enriched in LREEs relative to HREEs with(La/Yb)N ratios of 3.85-18.56 and underwent major fractionation with strongly negative Eu anomalies(Eu/Eu*=0.38-0.66).In the MORB-normalized trace element variation diagram,all the samples are enriched in Ce and large ion lithophile elements such as Rb,Th,and K,and depleted in high field strength elements such as Nb,and Ti,with negative Sr and Ti anomalies.The I-type granites are enriched in LREEs with slight negative Eu anomalies(Eu/Eu*=0.83-0.93).They are characterized by the enrichment of highly incompatible elements(such as K,Rb,Ba,Th)and LREEs,relative to MORB.Neodymium isotopic data show that the S-type granites display 143Nd/144Nd values of 0.51241-0.51256,and have eNa(t=1055 Ma)values of(-3.29)to(-3.81).Calculated tDM ages yield values from 1.87 to 1.91 Ga with the tDM.2stg ages of 1.86 to 1.9 Ga.The I-type granites have 143Nd/144Nd ratios between 0.51192 and 0.51195,corresponding to initial eNd(t=837 Ma)values of 1.22 to 5.63.Calculated tDM ages yield values from 1.0 to 1.38 Ga and the tDM.2stg ages yield values from 0.99 to 1.06 Ga.The S-type granites are distinguished as syn-collision granite,whereas the I-type granites were formed as arc magmas according to the Rb-(Yb+Ta)and R1-R2 tectonic discrimination diagrams.To conclude,there are two types of spatially associated granite,the Mesoproterozoic S-type granite which were derived from re-melting of upper crustal mudstone and/or clastics and resulted from the convergence of two continental plates,and the mid-Neoproterozoic I-type granite which formed in continental arc and resulted from mantle-derived magma mixed crust material,in the western Yangtze Block.Furthermore,we suggest that collision between the Yangtze and Cathaysia blocks occurred at about 1055 Ma,and caused the S-type granite.The I-type granite related to the subduction of oceanic lithosphere eastward underneath the Yangtze Block in the mid-Neoproterozoic.展开更多
Objective： To study the clinical effects of Prescription Zhuyun-Ⅲ （助孕3号方, ZYⅢ） on early pregnant women diagnosed as threatened abortion, and its mechanism in immunity and endocrine by determining serum Th1- a...Objective： To study the clinical effects of Prescription Zhuyun-Ⅲ （助孕3号方, ZYⅢ） on early pregnant women diagnosed as threatened abortion, and its mechanism in immunity and endocrine by determining serum Th1- and Th2-type cytokines, progesterone, and β-human chorionic gonadotropin （β-HCG）. Methods： The treatment group comprised 30 early pregnant women diagnosed as threatened abortion of deficiency syndrome of Pi （脾）, Shen （肾）, or both. The control group consisted of 20 normal early pregnant women of similar gestational age. Patients in the treatment group were administered with ZYⅢ for 4 weeks. Peripheral blood samples were collected pre- and post-treatment from both the treatment and the control groups. Serum Thl-type cytokine [interleukin-2 （IL-2）] and Th2-type cytokine [interleukin-10 （IL-10）] were determined by flow cytometry, and serum progesterone and 13-HCG were determined by ELISA. Results： （1） The treatment was effective in 26 and ineffective in 4 patients of the treatment group. Therefore, the cure percentage was 86.67%. （2） In the treatment group before the treatment, IL-2 was significantly higher, IL-10 tended to be less, and the Th1/Th2 balance shifted toward Thl compared with those in the control group. （3） After the treatment, IL-2 was decreased, IL-10 was increased, and IL-2/IL-10 was decreased. Both progesterone and β-HCG were increased. Changes of progesterone were positively correlated with changes of IL-10, whereas changes of β-HCG were negatively correlated with changes of IL-2. Conclusions： Our study suggests that ZYⅢ has an evident function of protecting the fetus, and one of its mechanisms is inhibiting the secretion of Thl cytokines, promoting the secretion of Th2 cytokines, and recovering the pathological shift of the Th1/Th2 balance. The other possible mechanism is increasing serum progesterone and β-HCG concentrations. Moreover, there are some correlations between the above two effects.展开更多
New whole-rock major and trace elements, and zircon U Pb and Hf-Nd isotope compositions are reported for the Karamay dikes, enclaves, and host granites in the West Junggar, NW China. Zircon U -Pb dating of the l（aram...New whole-rock major and trace elements, and zircon U Pb and Hf-Nd isotope compositions are reported for the Karamay dikes, enclaves, and host granites in the West Junggar, NW China. Zircon U -Pb dating of the l（aramay pluton yields an age of 300.7 ~ 2.3 Ma for the enclave and 300.0 ~ 2.6 Ma for the host granite, which was intruded by dike with an age of 298 Ma. The host granites exhibit relatively low SiO2 contents and A/CNK and Ga/Al ratios, low initial 87Sr/86Sr ratios （0.703421 0.703526） and positive eHf（t） （5.5--14.1） and eNd（t） （7.3--8.1） values with a young model age, suggesting that they are I-type granites and were mainly derived from a juvenile lower crustal source. The enclaves and dikes belong to an andesitic calc-alkaline series and have high MgO concentrations at low silica content and positive eHf（t） （7.6--13.2, 14.2--14.9） and εNd（t） （6.8-8.3, ~6.9） values. They are enriched in LILEs （Rb, Ba and U） and LREE and depleted in HFSEs （Nb and Ta） with insignificant negative Eu anomalies, indicating that the melts were derived from an enriched lithospheric mantle modified by subducted oceanic crust-derived melts and minor fluids, followed by fractional crystallization. The Karamay host granites and enclaves are of mixed origin and are most probably formed by the interaction between the lower crust-and lithospheric mantle-derived magmas, and were intruded by the unmixed dikes subsequently. The upwelling mantle through a slab window in an island arc environment might have triggered partial melting of the lithospheric mantle and its subsequent interaction with the granitic magma, further suggesting that the ridge subduction played an important role in the crustal growth of West lun^gar.展开更多
The Kejie pluton is located in the north of the Changning-Menglian suture zone. The rock types are mainly biotite-granite. Zircon LA-ICP-MS U-Pb dating indicates that the Kejie pluton emplaced at about 80-77 Ma, Late ...The Kejie pluton is located in the north of the Changning-Menglian suture zone. The rock types are mainly biotite-granite. Zircon LA-ICP-MS U-Pb dating indicates that the Kejie pluton emplaced at about 80-77 Ma, Late Cretaceous. The Kejie pluton samples are characterized by high SiO2 （71.68%-72.47%）, K2O （4.73%-5.54%）, total alkali （K2O ＋ Na2O = 8.21%-8.53%）, K2O/Na2O ratios （1.36-1.94） and low P2O5 （0.13%-0.17%）, with A/CNK of 1.025-1.055; enriched in U, Th, and K, depleted in Ba, Nb, St, Ti, P and Eu. They are highly fractionated, slightly peraluminous 1-type granite. The two samples of the Kejie pluton give a large variation of εHf（t） values （-5.04 to 1.96） and Hf isotope crustal model ages of 1.16-1.5 Ga. Zircon Hf isotopes and zircon saturation temperatures of whole-rock （801℃-823℃） show that the mantle-derived materials maybe have played a vital role in the generation of the Kejie pluton. The Kejie pluton was most likely generated in a setting associated with the eastward subduction of the neo-Tethys ocean, where intrusion of mantle wedge basaltic magmas in the crust caused the anatexis of the latter, forming hybrid melts, which subsequently experienced high-degree fractional crystallization.展开更多
We investigate deviation matrix for discrete-time GI/M/1-type Markov chains in terms of the matrix-analytic method, and revisit the link between deviation matrix and the asymptotic variance. Parallel results are obtai...We investigate deviation matrix for discrete-time GI/M/1-type Markov chains in terms of the matrix-analytic method, and revisit the link between deviation matrix and the asymptotic variance. Parallel results are obtained for continuous-time GI/M/1-type Markov chains based on the technique of uniformization. We conclude with A. B. Clarke＇s tandem queue as an illustrative example, and compute the asymptotic variance for the queue length for this model.展开更多
In 1965 Gohler introduced 2-normed spaces and since then, this topic have been intensively studied and developed. We shall introduce the notion of 1-type proximinal subspaces of 2-normed spaces and give some results i...In 1965 Gohler introduced 2-normed spaces and since then, this topic have been intensively studied and developed. We shall introduce the notion of 1-type proximinal subspaces of 2-normed spaces and give some results in this field.展开更多
Porcine epidemic diarrhea(PED)caused by the porcine epidemic diarrhea virus(PEDV),is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.An increased...Porcine epidemic diarrhea(PED)caused by the porcine epidemic diarrhea virus(PEDV),is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.An increased number of PED cases caused by variant PEDV have been reported in many countries since 2010.S protein is the main immunogenic protein containing some B-cell epitopes that can induce neutralizing antibodies of PEDV.In this study,the construction,expression and purification of Pseudomonas aeruginosa exotoxin A(PE)without domain Ⅲ(PE△Ⅲ)as a vector was performed for the delivery of PEDV S-A or S-B.PE(△Ⅲ)PEDV S-A and PE(△Ⅲ)PEDV S-B recombinant proteins were confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analysis.The immunogenicity of PEDV S-A and PEDV S-B subunit vaccines were evaluated in mice.The results showed that PEDV-S-B vaccine could not only induce specific humoral and Th1 type-dominant cellular immune responses,but also stimulate PEDV-specific mucosal immune responses in mice.PEDV-S-B subunit vaccine is a novel candidate mucosal vaccine against PEDV infection.展开更多
文摘An application of techniques is presented to construct G^(1 )smooth surfaces by using acombination of the rectangular and triangular Bezier patches of degree as low as possible. TheG^(1) smooth surfaces have the local property and interpolate the given data and inherit thetopology imposed by the given space convex quadrilateral partition and triangulation. The papergeneralizes current approaches for assembling of rectangular and triangular patches.
基金financially supported by the National Key Research and Development Program of China(Grant No.2016YFC0600308,SQ2018YFC060162)the China Geological Survey Project(Grant No.DD20160015,DD20160026)+1 种基金the International Scientific Plan of the Qinghai Xizang(Tibet)Plateau of Chengdu Center,China Geological Surveythe Natural Science Foundation of China(Grant No.41702080,41702086)
文摘The Jiangla'angzong granite in the northern part of the Central Lhasa Terrane is composed of syenogranite and adamellite.LA-ICP-MS zircon U-Pb analyses suggest that syenogranite has a weighted mean 2±6pb/23SU age of 86±1 Ma(mean square weighted deviation=0.37),which is in accordance with the muscovite Ar-Ar age(85±1 Ma)of Cu-Au ore-bearing skarns and the zircon U-Pb age(84±1 Ma)of adamellite.This suggests that the Jiangla'angzong magmatism and Cu-Au mineralization events took place during the Late Cretaceous.The granite contains hornblende,biotite,and pyroxene,and does not contain Al-bearing minerals,such as muscovite,cordierite,and garnet.It has high contents of SiO2(65.10-70.91wt%),K20(3.44-5.17wt%),and total K20+Na20(7.13-8.15wt%),and moderate contents of A12Oa(14.14-16.45wt%)and CaO(2.33-4.11wt%),with a Reitman index(δ43)of 2.18 to 2.33,and A/CNK values of 0.88 to 1.02.The P205 contents show a negative correlation with SiO2,whereas Pb contents show a positive correlation with SiO2.Th and Y contents are relatively low and show a negative correlation with the Rb contents.These characteristics suggest that the Jiangla'angzong granite is a high K calc-alkaline metaluminous I-type granite.It is enriched in light rare earth elements(LREE)and large ion lithofile elements(LILE),and depleted in heavy rare earth elements(HREE)and high field strength elements(HFSE),with LREE/HREE ratios of 11.7 to 18.1.The granite has negative Eu anomalies of 0.58 to 0.94 without obvious Ce anomalies(δCe=l.00-1.04).The relatively low initial a7Sr/a6Sr ratios of 0.7106 to 0.7179,positiveε±nt(t)values of 1.0 to 4.1,and two-stage Hf model ages(TDM2)ranging from 889 Ma to 1082 Ma,These geochemical features indicate that the granite derived from a juvenile crust.The(143Nd/144Nd)t values from the Jiangla'angzong granite range from 0.5121 to 0.5123,its eNd(t)values range from-10.17 to-6.10,its(^206pb/^204pb)t values range from 18.683 to 18.746,its(^207pb/^204pb)t values range from 15.695 to 15.700,and its(^208pb/^204pb)t values range from 39.012 to 39.071.These data indicate that the granite was formed by melting of the upper crust with the addition of some mantle materials.We propose that the Jiangla'angzong granite was formed during the post-collision extension of the Qiangtang and Lhasa terranes.
基金supported by the National Key R&D Program of China (No.2021YFB3501600)the Key R&D Program of Zhejiang Province (Nos.2021C01191 and 2021C01190).
文摘The excellent thermal stability of magnetic properties of Sm_(2)Co_(17)-based magnets is their most impor-tant feature.However,this stability is reduced when the maximum energy product of Sm_(2)Co_(17)-based magnets is improved,which is mainly determined by the Fe/Cu distribution of the 2:17R cell and 1:5H cell boundary phases.During the demagnetization process,the Cu-rich 1:5H cell boundary phase with a width of 2-15 nm obstructs the motion of the domain walls,yielding coercivity.Herein,we report a micron-scale Cu/Zr-rich and Fe-lean 1:5H-based precipitated phase with a lamellar structure,probably induced by Sm_(2)O_(3) doping.This structure enables the separate regulation of Fe and Cu distribution for Sm_(2)Co_(17)-based magnets with Fe-rich 2:17R cell phases and Cu-rich 1:5H cell boundary phases,consid-erably optimizing the thermal stability of magnetic properties.This discovery can be further developed to produce Sm_(2)Co_(17)-based magnets with high performance and excellent thermal stability of magnetic properties.
基金supported by the China Geological Survey project(1212011120623)
文摘In the western Yangtze Block,widespread Mesoproterozoic to Neoproterozoic rocks are the key to understanding the Precambrian tectonic-magmatic evolution of the region.However,their petrogenesis and tectonic setting are still controversial.In this paper,zircon U-Pb ages,Sm-Nd isotopic and whole-rock geochemical data are reported from selected fresh samples in the southern Dechang county,southwestern China,in order to constrain their emplacement age and magma source,as well as their petrogenesis and tectonic setting.They are mainly composed of biotite monzogranite,monzonitic granite,biotite granodiorites,and quartz diorite.Two ages of 1055±43 Ma and 837.6±3.8 Ma were obtained through zircon U-Pb dating by LA-ICP-MS and LA-MC-ICP-MS,respectively.According to their major element compositions,the Grenville-age granites are peraluminous calc-alkaline series calcic S-type granite.In contrast,the mid-Neoproterozoic granites are metaluminous calc-aikaline series alkalic I-type granite.Furthermore,the S-type granites are enriched in LREEs relative to HREEs with(La/Yb)N ratios of 3.85-18.56 and underwent major fractionation with strongly negative Eu anomalies(Eu/Eu*=0.38-0.66).In the MORB-normalized trace element variation diagram,all the samples are enriched in Ce and large ion lithophile elements such as Rb,Th,and K,and depleted in high field strength elements such as Nb,and Ti,with negative Sr and Ti anomalies.The I-type granites are enriched in LREEs with slight negative Eu anomalies(Eu/Eu*=0.83-0.93).They are characterized by the enrichment of highly incompatible elements(such as K,Rb,Ba,Th)and LREEs,relative to MORB.Neodymium isotopic data show that the S-type granites display 143Nd/144Nd values of 0.51241-0.51256,and have eNa(t=1055 Ma)values of(-3.29)to(-3.81).Calculated tDM ages yield values from 1.87 to 1.91 Ga with the tDM.2stg ages of 1.86 to 1.9 Ga.The I-type granites have 143Nd/144Nd ratios between 0.51192 and 0.51195,corresponding to initial eNd(t=837 Ma)values of 1.22 to 5.63.Calculated tDM ages yield values from 1.0 to 1.38 Ga and the tDM.2stg ages yield values from 0.99 to 1.06 Ga.The S-type granites are distinguished as syn-collision granite,whereas the I-type granites were formed as arc magmas according to the Rb-(Yb+Ta)and R1-R2 tectonic discrimination diagrams.To conclude,there are two types of spatially associated granite,the Mesoproterozoic S-type granite which were derived from re-melting of upper crustal mudstone and/or clastics and resulted from the convergence of two continental plates,and the mid-Neoproterozoic I-type granite which formed in continental arc and resulted from mantle-derived magma mixed crust material,in the western Yangtze Block.Furthermore,we suggest that collision between the Yangtze and Cathaysia blocks occurred at about 1055 Ma,and caused the S-type granite.The I-type granite related to the subduction of oceanic lithosphere eastward underneath the Yangtze Block in the mid-Neoproterozoic.
基金Supported by Guangdong Province Key Scientific and Technological Project(No.C30103)
文摘Objective： To study the clinical effects of Prescription Zhuyun-Ⅲ （助孕3号方, ZYⅢ） on early pregnant women diagnosed as threatened abortion, and its mechanism in immunity and endocrine by determining serum Th1- and Th2-type cytokines, progesterone, and β-human chorionic gonadotropin （β-HCG）. Methods： The treatment group comprised 30 early pregnant women diagnosed as threatened abortion of deficiency syndrome of Pi （脾）, Shen （肾）, or both. The control group consisted of 20 normal early pregnant women of similar gestational age. Patients in the treatment group were administered with ZYⅢ for 4 weeks. Peripheral blood samples were collected pre- and post-treatment from both the treatment and the control groups. Serum Thl-type cytokine [interleukin-2 （IL-2）] and Th2-type cytokine [interleukin-10 （IL-10）] were determined by flow cytometry, and serum progesterone and 13-HCG were determined by ELISA. Results： （1） The treatment was effective in 26 and ineffective in 4 patients of the treatment group. Therefore, the cure percentage was 86.67%. （2） In the treatment group before the treatment, IL-2 was significantly higher, IL-10 tended to be less, and the Th1/Th2 balance shifted toward Thl compared with those in the control group. （3） After the treatment, IL-2 was decreased, IL-10 was increased, and IL-2/IL-10 was decreased. Both progesterone and β-HCG were increased. Changes of progesterone were positively correlated with changes of IL-10, whereas changes of β-HCG were negatively correlated with changes of IL-2. Conclusions： Our study suggests that ZYⅢ has an evident function of protecting the fetus, and one of its mechanisms is inhibiting the secretion of Thl cytokines, promoting the secretion of Th2 cytokines, and recovering the pathological shift of the Th1/Th2 balance. The other possible mechanism is increasing serum progesterone and β-HCG concentrations. Moreover, there are some correlations between the above two effects.
基金financially supported by the National Science and Technology Major Project(No. 2011ZX05008-001)the National Natural Science Foundation of China(No.40739906)the Chinese State 973 Project(No. 2011CB201100)
文摘New whole-rock major and trace elements, and zircon U Pb and Hf-Nd isotope compositions are reported for the Karamay dikes, enclaves, and host granites in the West Junggar, NW China. Zircon U -Pb dating of the l（aramay pluton yields an age of 300.7 ~ 2.3 Ma for the enclave and 300.0 ~ 2.6 Ma for the host granite, which was intruded by dike with an age of 298 Ma. The host granites exhibit relatively low SiO2 contents and A/CNK and Ga/Al ratios, low initial 87Sr/86Sr ratios （0.703421 0.703526） and positive eHf（t） （5.5--14.1） and eNd（t） （7.3--8.1） values with a young model age, suggesting that they are I-type granites and were mainly derived from a juvenile lower crustal source. The enclaves and dikes belong to an andesitic calc-alkaline series and have high MgO concentrations at low silica content and positive eHf（t） （7.6--13.2, 14.2--14.9） and εNd（t） （6.8-8.3, ~6.9） values. They are enriched in LILEs （Rb, Ba and U） and LREE and depleted in HFSEs （Nb and Ta） with insignificant negative Eu anomalies, indicating that the melts were derived from an enriched lithospheric mantle modified by subducted oceanic crust-derived melts and minor fluids, followed by fractional crystallization. The Karamay host granites and enclaves are of mixed origin and are most probably formed by the interaction between the lower crust-and lithospheric mantle-derived magmas, and were intruded by the unmixed dikes subsequently. The upwelling mantle through a slab window in an island arc environment might have triggered partial melting of the lithospheric mantle and its subsequent interaction with the granitic magma, further suggesting that the ridge subduction played an important role in the crustal growth of West lun^gar.
基金financially supported by the Programme of the China Geological Survey (No.1212011120608, No.1212011220907)the National Key Projects for Basic Research of China (No.2009CB421002, No.2011CB403102)+2 种基金NSF of China (No. 40672044)Program for Changjiang Scholars, Innovative Research Team in University (No.IRT1083)111 project (No.B07011)
文摘The Kejie pluton is located in the north of the Changning-Menglian suture zone. The rock types are mainly biotite-granite. Zircon LA-ICP-MS U-Pb dating indicates that the Kejie pluton emplaced at about 80-77 Ma, Late Cretaceous. The Kejie pluton samples are characterized by high SiO2 （71.68%-72.47%）, K2O （4.73%-5.54%）, total alkali （K2O ＋ Na2O = 8.21%-8.53%）, K2O/Na2O ratios （1.36-1.94） and low P2O5 （0.13%-0.17%）, with A/CNK of 1.025-1.055; enriched in U, Th, and K, depleted in Ba, Nb, St, Ti, P and Eu. They are highly fractionated, slightly peraluminous 1-type granite. The two samples of the Kejie pluton give a large variation of εHf（t） values （-5.04 to 1.96） and Hf isotope crustal model ages of 1.16-1.5 Ga. Zircon Hf isotopes and zircon saturation temperatures of whole-rock （801℃-823℃） show that the mantle-derived materials maybe have played a vital role in the generation of the Kejie pluton. The Kejie pluton was most likely generated in a setting associated with the eastward subduction of the neo-Tethys ocean, where intrusion of mantle wedge basaltic magmas in the crust caused the anatexis of the latter, forming hybrid melts, which subsequently experienced high-degree fractional crystallization.
基金Acknowledgements This work was supported in part by the National Natural Science Foundation of China （Grant No. 11211120]44） and the Fundamental Research Funds for the Central Universities （Grant 2010QYZD001）.
文摘We investigate deviation matrix for discrete-time GI/M/1-type Markov chains in terms of the matrix-analytic method, and revisit the link between deviation matrix and the asymptotic variance. Parallel results are obtained for continuous-time GI/M/1-type Markov chains based on the technique of uniformization. We conclude with A. B. Clarke＇s tandem queue as an illustrative example, and compute the asymptotic variance for the queue length for this model.
文摘In 1965 Gohler introduced 2-normed spaces and since then, this topic have been intensively studied and developed. We shall introduce the notion of 1-type proximinal subspaces of 2-normed spaces and give some results in this field.
基金This research was funded by the National Natural Science Foundation of China(31900746 and 31802170)Postdoctoral Science Foundation(2019M660182).
文摘Porcine epidemic diarrhea(PED)caused by the porcine epidemic diarrhea virus(PEDV),is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.An increased number of PED cases caused by variant PEDV have been reported in many countries since 2010.S protein is the main immunogenic protein containing some B-cell epitopes that can induce neutralizing antibodies of PEDV.In this study,the construction,expression and purification of Pseudomonas aeruginosa exotoxin A(PE)without domain Ⅲ(PE△Ⅲ)as a vector was performed for the delivery of PEDV S-A or S-B.PE(△Ⅲ)PEDV S-A and PE(△Ⅲ)PEDV S-B recombinant proteins were confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analysis.The immunogenicity of PEDV S-A and PEDV S-B subunit vaccines were evaluated in mice.The results showed that PEDV-S-B vaccine could not only induce specific humoral and Th1 type-dominant cellular immune responses,but also stimulate PEDV-specific mucosal immune responses in mice.PEDV-S-B subunit vaccine is a novel candidate mucosal vaccine against PEDV infection.
