The di-zhen (DZ) is an ancient type of acupuncture needle with a history dating back to more than 2000 years. Unlike modern acupuncture needles, the DZ is not inserted subcutaneously and is considered to be safe for c...The di-zhen (DZ) is an ancient type of acupuncture needle with a history dating back to more than 2000 years. Unlike modern acupuncture needles, the DZ is not inserted subcutaneously and is considered to be safe for common use, even at the bedside of terminally ill patients. In this case study, DZ application was selected and applied 14 times on a 92-year-old patient who had suffered severe oliguria along with administration of diuretics. Urine volume increased 12 out of 14 times following DZ treatment;however, the other two times it was ineffective. To investigate the reason and the differences in effective/ineffective DZ application, two internal conditions (effective vs ineffective) were compared by analyzing daily nursing reports (vital signs such as blood pressure, urine volume and body temperature) and weekly clinical data (including renal, liver and immune function, urea nitrogen, creatinine, ALT, AST, the ratio and number of leukocytes, erythrocytes). DZ application increased urine volume via a transient modification of the autonomic nervous system when internal homeostasis was maintained. Aging populations, who often have several diseases and medications, are rapidly increasing in developed countries. Therefore, the study and application of DZ may contribute to a reduction in medical costs, which have been rapidly and heavily expanding recently.展开更多
The genetic polymorphism of SLA-DQA gene was investigated by PCR-RFLP. The effects of SLA.DQA gene on birth weight and 30-day-old weight were analyzed in 250 individuals of FI hybrid pig （ Heilongjiang wild boar x Be...The genetic polymorphism of SLA-DQA gene was investigated by PCR-RFLP. The effects of SLA.DQA gene on birth weight and 30-day-old weight were analyzed in 250 individuals of FI hybrid pig （ Heilongjiang wild boar x Beijing Black sow）. The analysis revealed four poly- morphic loci in the SLA-DQA gene, but only the Pvu II locus in exon 2 of SLA-DQA gene （ BB genotype） greatly increased the 30-day-old weight of piglets.展开更多
Malaria is uncontrolled burden in the world till now.Despite of different efforts to develop antimalarial drug for decades,any anti-malarial drug can able to eradicate completely till now.Many anti-malarial substances...Malaria is uncontrolled burden in the world till now.Despite of different efforts to develop antimalarial drug for decades,any anti-malarial drug can able to eradicate completely till now.Many anti-malarial substances are practically ineffectual because of their physicochemical limitations,cytotoxicity,chemical instability and degradation,and limited activities against intracellular parasites.Taking into consideration,the amount of research is going to conduct in the field of nanoparticle based drug delivery systems,lead to new ways of improving the treatment of infectious diseases.The study has focused on the progress and advancement of research on nanotechnology based drug delivery to eradicate the malaria.We like to focus the efficacy of nanotechnology based drug application for the opening out of novel chemotherapeutics in laboratory research,which may show the way to better use with age-old antimalarial drug and may draw the attention of pharmaceutical industries for the improvement and designing of effective anti-malarial drugs in future.展开更多
The purpose was to examine and compare the psychometric properties of a Mexican Spanish version of the WHOQOL-OLD module. The instrument was applied to 285 individuals aged over 60 years (mean = 69.26, SD = 6.52). All...The purpose was to examine and compare the psychometric properties of a Mexican Spanish version of the WHOQOL-OLD module. The instrument was applied to 285 individuals aged over 60 years (mean = 69.26, SD = 6.52). All participants completed a demographic data sheet, the WHOQOL-OLD, the Beck Depression Inventory (BDI), and the Geriatric Depression Scale (GDS);182 of the 285 participants also completed a quality of life questionnaire for diabetic patients (DQOL). Acceptable levels of reliability were found, with Cronbach’s alpha values between 0.70 and 0.90 for overall quality of life and all domains except for autonomy, where the alpha value was low. The exploratory factor analysis carried out to examine the construct validity of the instrument yielded six domains: sensory abilities, autonomy, past/present/future activities, social participation, death and dying, and intimacy (explained variance of 62.95%). The mean overall quality of life score was 94.86 (SD = 13.68, range 50 to 120). The WHOQOL-OLD module showed criterion validity and concurrent validity with respect to the BDI (r = -0.516, p = 0.034), the GDS (r = -0.336, p = 0.002), and the DQOL (n = 182, r = 0.159, p = 0.032). Discriminant validity was also confirmed with respect to self-perceived health (t = 2.701, d.f. = 225, p = 0.007) and education (F(3, 280) = 9.015, p p > 0.05). We conclude that the Mexican Spanish version of the WHOQOL-OLD module has adequate psychometric properties.展开更多
This study was conducted to investigate the effects of different concentrations ofβ-mercaptoethanol on the development ability of oocytes in Dorper sheep at the age of 6 weeks.In this study,6 Dorper sheep of 6 weeks ...This study was conducted to investigate the effects of different concentrations ofβ-mercaptoethanol on the development ability of oocytes in Dorper sheep at the age of 6 weeks.In this study,6 Dorper sheep of 6 weeks old were chosen to induce oocyte collection in vivo by gonadotropin,and A and B grade cumulus oocyte complexes were obtained(COCs)with different concentrations of(0,50,70 and 100μmol/L)ofβ-mercaptoethanol in the mature liquid.The cleavage rate and blastocyst rate were counted after matured oocytes and capacitated sperm were co-incubated and fertilized eggs were cultivated.The results showed that compared with the cleavage rate(59.13%)and the blastocyst rate(12.17%)of the control group,the cleavage rates(60.87%,63.48%and 65.22%)and blastocyst rates(14.78%,17.39%and 21.74%)of the test groups I,II and III were higher(P>0.05),and the order was test group III>test group II>test group I>control group.The cleavage rate and blastocyst rate of the 100μmol/Lβ-mercaptoethanol group increased by 6.09 percentage points and 9.57 percentage points,respectively.It indicated that the addition of a certain amount ofβ-mercaptoethanol in the mature liquid could improve the developmental ability of oocytes and the quality of fertilized eggs of the 6-week-old Doper sheep.When theβ-mercaptoethanol concentration was within 100μmol/L,the cleavage rate and the blastocyst rate of oocytes were on the rise.The optimal concentration ofβ-mercaptoethanol in the mature liquid still needs further study.展开更多
The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl. It was an 11</span><span style="font-family:Verdana;">-</span><span style=&qu...The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl. It was an 11</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">year</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">old girl weighing 22 kg, admitted for exertional dyspnea, dry cough, palpitations, hepatitis, abdominal bloating, fever evolving for more than 9 months without a history of known cardiovascular disease;referral from a pulmonology department for cardiomegaly and right pleurisy.</span><span style="font-family:""> </span><span style="font-family:Verdana;">At cardiac auscultation, the rhythm was irregular</span><span style="font-family:Verdana;">ly</span><span style="font-family:Verdana;"> fast at 130 beats without added noise with a blood pressure of 110/65</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">mmhg. In the lungs, there was silence and a decrease in vocal vibrations at the right base, SaO</span><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;"> at 70%. Elsewhere a thoracic collateral venous circulation was visible. Electrocardiogram recorded rapid atrial fibrillation at 134 cycles. The cardiac ultrasound concluded that there was a mobile mass in the right atrium prolapsing in the right ventricle measuring 25 mm × 18.9 mm suggesting a myxoma. The myxoma of the right atrium is of a rare localization with a polymorphic clinical manifestation. It should be diagnosed as early as possible to avoid the occurrence of dreaded complications. Its management is surgical.展开更多
Female genital mutilation (FGM) is still a topical practice in several African regions or countries. They constitute a violation of human rights, in particular because of their harmful consequences for the health of t...Female genital mutilation (FGM) is still a topical practice in several African regions or countries. They constitute a violation of human rights, in particular because of their harmful consequences for the health of the people who suffer them and are the source of various complications. We report a case of FGM complications in the form of total coalescence of the labia majora with a small hole from which urine flows permanently. The management was a disinfubilation with suturing of the edges and urethral reimplantation and the evolution was favorable with complete healing after two (2) weeks.展开更多
INTRODUCTION Although the differential diagnosis for chest wall masses is broad, the vast majority are abscesses, lipomas, or sebaceous cysts. Post-operative chest wall masses can also include infection, hematoma, ser...INTRODUCTION Although the differential diagnosis for chest wall masses is broad, the vast majority are abscesses, lipomas, or sebaceous cysts. Post-operative chest wall masses can also include infection, hematoma, seroma, cancer recurrence, metastasis, and lung hernia. Bedside ultrasound has been well documented to be beneficial in the differentiation of superficial pathology. Pleurocutaneous fistula is a pathologic communication between the pleural space and subcutaneous tissues of the chest wall. Pleurocutaneous fistula is a rare complication of tube thoracostomy, video-assisted thoracic surgery （VATS） procedures, and various pulmonary infections.展开更多
基于2020年中国老年社会追踪调查(China Longitudinal Aging Social Survey,CLASS)数据,选取60岁及以上的老年人作为研究对象,探讨童年逆境与老年社会适应之间的关系,并分析认知功能的中介作用以及数字素养的调节作用。相关性分析结果显...基于2020年中国老年社会追踪调查(China Longitudinal Aging Social Survey,CLASS)数据,选取60岁及以上的老年人作为研究对象,探讨童年逆境与老年社会适应之间的关系,并分析认知功能的中介作用以及数字素养的调节作用。相关性分析结果显示,童年逆境、认知功能、数字素养、社会适应之间具有相关关系,且有统计学意义(P<0.01)。回归分析和中介效应分析结果显示,童年逆境与老年社会适应呈负向关联(β=-0.386,P<0.01)、与认知功能呈负向关联(β=-0.353,P<0.01);认知功能与老年社会适应呈正向关联(β=0.183,P<0.01);认知功能在童年逆境和老年社会适应之间起部分中介作用,中介效应量占总效应量的14.41%。有调节的中介效应分析结果显示,童年逆境与数字素养的交互项对认知功能的影响有统计学意义(β=0.148,P<0.01),即数字素养调节了童年逆境与认知功能之间的关系。据此提出以下建议:通过社区健康档案与老年人能力评估体系,识别并关注童年逆境经历较多的老年群体;深化数字赋能,将老年人数字素养提升全面融入智慧健康养老新业态培育中;强化跨部门协同与政策整合,建立促进老年人社会适应的长效支撑体系。展开更多
文摘The di-zhen (DZ) is an ancient type of acupuncture needle with a history dating back to more than 2000 years. Unlike modern acupuncture needles, the DZ is not inserted subcutaneously and is considered to be safe for common use, even at the bedside of terminally ill patients. In this case study, DZ application was selected and applied 14 times on a 92-year-old patient who had suffered severe oliguria along with administration of diuretics. Urine volume increased 12 out of 14 times following DZ treatment;however, the other two times it was ineffective. To investigate the reason and the differences in effective/ineffective DZ application, two internal conditions (effective vs ineffective) were compared by analyzing daily nursing reports (vital signs such as blood pressure, urine volume and body temperature) and weekly clinical data (including renal, liver and immune function, urea nitrogen, creatinine, ALT, AST, the ratio and number of leukocytes, erythrocytes). DZ application increased urine volume via a transient modification of the autonomic nervous system when internal homeostasis was maintained. Aging populations, who often have several diseases and medications, are rapidly increasing in developed countries. Therefore, the study and application of DZ may contribute to a reduction in medical costs, which have been rapidly and heavily expanding recently.
基金supported by the Key Projects in the National Science & Technology Pillar Program in the 11th Five Years (2008BADB2B02)
文摘The genetic polymorphism of SLA-DQA gene was investigated by PCR-RFLP. The effects of SLA.DQA gene on birth weight and 30-day-old weight were analyzed in 250 individuals of FI hybrid pig （ Heilongjiang wild boar x Beijing Black sow）. The analysis revealed four poly- morphic loci in the SLA-DQA gene, but only the Pvu II locus in exon 2 of SLA-DQA gene （ BB genotype） greatly increased the 30-day-old weight of piglets.
文摘Malaria is uncontrolled burden in the world till now.Despite of different efforts to develop antimalarial drug for decades,any anti-malarial drug can able to eradicate completely till now.Many anti-malarial substances are practically ineffectual because of their physicochemical limitations,cytotoxicity,chemical instability and degradation,and limited activities against intracellular parasites.Taking into consideration,the amount of research is going to conduct in the field of nanoparticle based drug delivery systems,lead to new ways of improving the treatment of infectious diseases.The study has focused on the progress and advancement of research on nanotechnology based drug delivery to eradicate the malaria.We like to focus the efficacy of nanotechnology based drug application for the opening out of novel chemotherapeutics in laboratory research,which may show the way to better use with age-old antimalarial drug and may draw the attention of pharmaceutical industries for the improvement and designing of effective anti-malarial drugs in future.
文摘The purpose was to examine and compare the psychometric properties of a Mexican Spanish version of the WHOQOL-OLD module. The instrument was applied to 285 individuals aged over 60 years (mean = 69.26, SD = 6.52). All participants completed a demographic data sheet, the WHOQOL-OLD, the Beck Depression Inventory (BDI), and the Geriatric Depression Scale (GDS);182 of the 285 participants also completed a quality of life questionnaire for diabetic patients (DQOL). Acceptable levels of reliability were found, with Cronbach’s alpha values between 0.70 and 0.90 for overall quality of life and all domains except for autonomy, where the alpha value was low. The exploratory factor analysis carried out to examine the construct validity of the instrument yielded six domains: sensory abilities, autonomy, past/present/future activities, social participation, death and dying, and intimacy (explained variance of 62.95%). The mean overall quality of life score was 94.86 (SD = 13.68, range 50 to 120). The WHOQOL-OLD module showed criterion validity and concurrent validity with respect to the BDI (r = -0.516, p = 0.034), the GDS (r = -0.336, p = 0.002), and the DQOL (n = 182, r = 0.159, p = 0.032). Discriminant validity was also confirmed with respect to self-perceived health (t = 2.701, d.f. = 225, p = 0.007) and education (F(3, 280) = 9.015, p p > 0.05). We conclude that the Mexican Spanish version of the WHOQOL-OLD module has adequate psychometric properties.
基金Supported by Earmarked Fund for Construction of National Wool Sheep Industry Technology Research System(CARS-39-24)Fund for Science and Technology Innovation Team in Shanxi Province(201705D131028-20)
文摘This study was conducted to investigate the effects of different concentrations ofβ-mercaptoethanol on the development ability of oocytes in Dorper sheep at the age of 6 weeks.In this study,6 Dorper sheep of 6 weeks old were chosen to induce oocyte collection in vivo by gonadotropin,and A and B grade cumulus oocyte complexes were obtained(COCs)with different concentrations of(0,50,70 and 100μmol/L)ofβ-mercaptoethanol in the mature liquid.The cleavage rate and blastocyst rate were counted after matured oocytes and capacitated sperm were co-incubated and fertilized eggs were cultivated.The results showed that compared with the cleavage rate(59.13%)and the blastocyst rate(12.17%)of the control group,the cleavage rates(60.87%,63.48%and 65.22%)and blastocyst rates(14.78%,17.39%and 21.74%)of the test groups I,II and III were higher(P>0.05),and the order was test group III>test group II>test group I>control group.The cleavage rate and blastocyst rate of the 100μmol/Lβ-mercaptoethanol group increased by 6.09 percentage points and 9.57 percentage points,respectively.It indicated that the addition of a certain amount ofβ-mercaptoethanol in the mature liquid could improve the developmental ability of oocytes and the quality of fertilized eggs of the 6-week-old Doper sheep.When theβ-mercaptoethanol concentration was within 100μmol/L,the cleavage rate and the blastocyst rate of oocytes were on the rise.The optimal concentration ofβ-mercaptoethanol in the mature liquid still needs further study.
文摘The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl. It was an 11</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">year</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">old girl weighing 22 kg, admitted for exertional dyspnea, dry cough, palpitations, hepatitis, abdominal bloating, fever evolving for more than 9 months without a history of known cardiovascular disease;referral from a pulmonology department for cardiomegaly and right pleurisy.</span><span style="font-family:""> </span><span style="font-family:Verdana;">At cardiac auscultation, the rhythm was irregular</span><span style="font-family:Verdana;">ly</span><span style="font-family:Verdana;"> fast at 130 beats without added noise with a blood pressure of 110/65</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">mmhg. In the lungs, there was silence and a decrease in vocal vibrations at the right base, SaO</span><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;"> at 70%. Elsewhere a thoracic collateral venous circulation was visible. Electrocardiogram recorded rapid atrial fibrillation at 134 cycles. The cardiac ultrasound concluded that there was a mobile mass in the right atrium prolapsing in the right ventricle measuring 25 mm × 18.9 mm suggesting a myxoma. The myxoma of the right atrium is of a rare localization with a polymorphic clinical manifestation. It should be diagnosed as early as possible to avoid the occurrence of dreaded complications. Its management is surgical.
文摘Female genital mutilation (FGM) is still a topical practice in several African regions or countries. They constitute a violation of human rights, in particular because of their harmful consequences for the health of the people who suffer them and are the source of various complications. We report a case of FGM complications in the form of total coalescence of the labia majora with a small hole from which urine flows permanently. The management was a disinfubilation with suturing of the edges and urethral reimplantation and the evolution was favorable with complete healing after two (2) weeks.
文摘INTRODUCTION Although the differential diagnosis for chest wall masses is broad, the vast majority are abscesses, lipomas, or sebaceous cysts. Post-operative chest wall masses can also include infection, hematoma, seroma, cancer recurrence, metastasis, and lung hernia. Bedside ultrasound has been well documented to be beneficial in the differentiation of superficial pathology. Pleurocutaneous fistula is a pathologic communication between the pleural space and subcutaneous tissues of the chest wall. Pleurocutaneous fistula is a rare complication of tube thoracostomy, video-assisted thoracic surgery （VATS） procedures, and various pulmonary infections.
文摘基于2020年中国老年社会追踪调查(China Longitudinal Aging Social Survey,CLASS)数据,选取60岁及以上的老年人作为研究对象,探讨童年逆境与老年社会适应之间的关系,并分析认知功能的中介作用以及数字素养的调节作用。相关性分析结果显示,童年逆境、认知功能、数字素养、社会适应之间具有相关关系,且有统计学意义(P<0.01)。回归分析和中介效应分析结果显示,童年逆境与老年社会适应呈负向关联(β=-0.386,P<0.01)、与认知功能呈负向关联(β=-0.353,P<0.01);认知功能与老年社会适应呈正向关联(β=0.183,P<0.01);认知功能在童年逆境和老年社会适应之间起部分中介作用,中介效应量占总效应量的14.41%。有调节的中介效应分析结果显示,童年逆境与数字素养的交互项对认知功能的影响有统计学意义(β=0.148,P<0.01),即数字素养调节了童年逆境与认知功能之间的关系。据此提出以下建议:通过社区健康档案与老年人能力评估体系,识别并关注童年逆境经历较多的老年群体;深化数字赋能,将老年人数字素养提升全面融入智慧健康养老新业态培育中;强化跨部门协同与政策整合,建立促进老年人社会适应的长效支撑体系。
