Given their unique structure-dependent properties,strategically designing semiconductor-based photocatalysts,which expose highly reactive crystalline facets,is widely used to tune their performance.Herein,AgBr/Ag/TiO_...Given their unique structure-dependent properties,strategically designing semiconductor-based photocatalysts,which expose highly reactive crystalline facets,is widely used to tune their performance.Herein,AgBr/Ag/TiO_(2){100}nanorods Z-scheme heterojunction composites were prepared via hydrothermal and in situ facet-induced reduction.Transmission electron microscopy,X-ray diffraction,X-ray photoelectron spectroscopy,electron paramagnetic resonance spectroscopy,and density functional theory calculations reveal that the selective exposure of TiO_(2){100}facets with abundant oxygen vacancies(OV)promotes the formation of metallic silver on the interfaces between AgBr and TiO_(2){100}.Metallic silver can mediate interfacial charge transfer by facilitating the photogenerated carrier recombination of the conduction band of TiO_(2){100}and the valence band of AgBr.As a result,a Z-scheme heterojunction is formed in AgBr/Ag/TiO_(2){100}.The AgBr/Ag/TiO_(2){100}exhibits faster degradation of tetracycline in aqueous solution compared to pristine AgBr,TiO_(2){101},TiO_(2){100}and AgBr/TiO_(2){101}p-n heterojunctions.This is attributed to the effect of the Z-scheme heterojunction on prolonging the lifetime of photogenerated carriers,which is confirmed by femtosecond transient absorption spectroscopy.The photocatalytic mechanism and degradation pathways are discussed along with a toxicity assessment of the intermediates.Overall,this work develops a new approach for designing Z-scheme heterojunction photocatalysts via selective facet control of anatase TiO_(2).展开更多
Micro-sized anatase TiO_(2) displays inferior capacity as cathode material for magnesium ion batteries because of the higher diffusion energy barrier of Mg^(2+)in anatase TiO_(2) lattice.Herein,we report that nanosize...Micro-sized anatase TiO_(2) displays inferior capacity as cathode material for magnesium ion batteries because of the higher diffusion energy barrier of Mg^(2+)in anatase TiO_(2) lattice.Herein,we report that nanosized anatase TiO_(2) exposed(001)facet doubles the capacity compared to the micro-sized sample ascribed to the interfacial Mg^(2+)ion storage.First-principles calculations reveal that the diffusion energy barrier of Mg^(2+)on the(001)facet is significantly lower than those in the bulk phase and on(100)facet,and the adsorption energy of Mg^(2+)on the(001)facet is also considerably lower than that on(100)facet,which guarantees superior interfacial Mg^(2+)storage of(001)facet.Moreover,anatase TiO_(2) exposed(001)facet displays a significantly higher capacity of 312.9 mAh g^(−1) in Mg-Li dual-salt electrolyte compared to 234.3 mAh g^(−1) in Li salt electrolyte.The adsorption energies of Mg^(2+)on(001)facet are much lower than the adsorption energies of Li+on(001)facet,implying that the Mg^(2+)ion interfacial storage is more favorable.These results highlight that controlling the crystal facet of the nanocrystals effectively enhances the interfacial storage of multivalent ions.This work offers valuable guidance for the rational design of high-capacity storage systems.展开更多
【背景】酪蛋白水解蛋白酶L(caseinolytic protease L,ClpL)是热休克蛋白100(heat shock protein 100,HSP100)家族成员,参与多种细胞内生物学过程包括应激耐受反应、长期存活、毒力和抗生素抗性等,在病原菌的致病过程中发挥重要作用。...【背景】酪蛋白水解蛋白酶L(caseinolytic protease L,ClpL)是热休克蛋白100(heat shock protein 100,HSP100)家族成员,参与多种细胞内生物学过程包括应激耐受反应、长期存活、毒力和抗生素抗性等,在病原菌的致病过程中发挥重要作用。【目的】阐明HSP100/ClpL对猪链球菌2型(Streptococcus suis type 2)强毒株的应激耐受和毒力的影响。【方法】利用温敏自杀质粒pSET4s构建了SsClpL基因缺失株ΔclpL;利用大肠杆菌-猪链球菌穿梭质粒pSET2构建了互补株CΔclpL;比较亲本株SS2-1、ΔclpL和CΔclpL在各种应激环境(高温、氧化性应激和酸应激)和血液中的生存能力;利用小鼠感染模型和体内竞争试验评价clpL缺失前后细菌的毒力变化。【结果】clpL缺失后,SS2在各种应激环境中的生存能力明显减弱;同时在猪全血中的存活能力也显著降低;对BALB/c小鼠的致病力有所降低,在体内的定殖能力明显降低。【结论】SsClpL与猪链球菌的应激耐受和致病性密切相关。展开更多
目的探析脑梗死患者髓鞘碱性蛋白(myelin basic protein,MBP)、S100钙结合蛋白B(S100 calcium-binding protein B,S100-B)水平与介入治疗后早期神经功能恶化的关联性。方法纳入2021年7月–2024年7月期间本院收治的258例脑梗死患者,采用...目的探析脑梗死患者髓鞘碱性蛋白(myelin basic protein,MBP)、S100钙结合蛋白B(S100 calcium-binding protein B,S100-B)水平与介入治疗后早期神经功能恶化的关联性。方法纳入2021年7月–2024年7月期间本院收治的258例脑梗死患者,采用美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分评估患者的神经功能状况,将死亡患者或介入治疗24 h后NIHSS评分增加4分及以上患者纳入早期神经功能恶化组,其余患者纳入未恶化组。测定所有患者MBP、S100-B水平,并分析其水平变化与介入治疗后神经功能恶化风险的关系。结果脑梗死患者早期神经功能恶化组血清MBP、S100-B水平高于未恶化组〔t=9.062(95%CI:2.348~3.663)、7.708(95%CI:0.221~0.375),P<0.001〕;Spearman相关性显示:恶化组血清MBP、S100-B水平与NIHSS评分增加情况呈正相关〔r=0.323(95%CI:0.095~0.542)、0.292(95%CI:0.066~0.488),P<0.05〕;分层回归分析显示:血清MBP〔比值比(odds ratio,OR)=1.996,95%CI:1.607~2.478〕、S100-B(OR=1.005,95%CI:1.003~1.007)水平是影响脑梗死患者早期神经功能恶化的危险因素(P<0.05),即使校正混杂因素后依然是其危险因素,此外入院NIHSS评分(OR=1.224,95%CI:1.142~1.310)及合并高血压(OR=2.542,95%CI:1.139~5.669)、高脂血症(OR=2.618,95%CI:1.101~6.228),其中入院NIHSS评分与MBP存在交互作用(OR=1.081,95%CI:1.034~1.130);受试者工作特征曲线显示:血清MBP、S100-B水平评估脑梗死患者早期神经功能恶化的曲线下面积分别为0.822(95%CI:0.764~0.879)、0.788(95%CI:0.724~0.853)。结论脑梗死患者介入治疗后血清MBP、S100-B水平较高与早期神经功能恶化风险相关,且对神经功能恶化风险有一定的评估价值。展开更多
A large diamond crystal up to 500 μm in diameter with a smooth （100） facet at its top has been synthesized on Mo substrate through microwave plasma chemical vapor deposition （MPCVD）. Its morphology and quality we...A large diamond crystal up to 500 μm in diameter with a smooth （100） facet at its top has been synthesized on Mo substrate through microwave plasma chemical vapor deposition （MPCVD）. Its morphology and quality were characterized by scanning electron microscopy （SEM）, and the growth mechanism was roughly illustrated from both macroscopic and microscopic viewpoints. It was found that morphological instabilities are a major factor resulting in synthesis of large diamond crystals, moreover, high microwave power density （MPD）, high CH4 concentrations, high pressure, high substrate surface temperature and the addition of a small amount of O2 were also necessary for the synthesis of large diamond crystals.展开更多
文摘Given their unique structure-dependent properties,strategically designing semiconductor-based photocatalysts,which expose highly reactive crystalline facets,is widely used to tune their performance.Herein,AgBr/Ag/TiO_(2){100}nanorods Z-scheme heterojunction composites were prepared via hydrothermal and in situ facet-induced reduction.Transmission electron microscopy,X-ray diffraction,X-ray photoelectron spectroscopy,electron paramagnetic resonance spectroscopy,and density functional theory calculations reveal that the selective exposure of TiO_(2){100}facets with abundant oxygen vacancies(OV)promotes the formation of metallic silver on the interfaces between AgBr and TiO_(2){100}.Metallic silver can mediate interfacial charge transfer by facilitating the photogenerated carrier recombination of the conduction band of TiO_(2){100}and the valence band of AgBr.As a result,a Z-scheme heterojunction is formed in AgBr/Ag/TiO_(2){100}.The AgBr/Ag/TiO_(2){100}exhibits faster degradation of tetracycline in aqueous solution compared to pristine AgBr,TiO_(2){101},TiO_(2){100}and AgBr/TiO_(2){101}p-n heterojunctions.This is attributed to the effect of the Z-scheme heterojunction on prolonging the lifetime of photogenerated carriers,which is confirmed by femtosecond transient absorption spectroscopy.The photocatalytic mechanism and degradation pathways are discussed along with a toxicity assessment of the intermediates.Overall,this work develops a new approach for designing Z-scheme heterojunction photocatalysts via selective facet control of anatase TiO_(2).
基金supported by the National Key R&D Program of China(No.2023YFB3809500)the Fundamental Research Funds for the Central Universities(No.2024CDJXY003)+1 种基金the Venture&Innovation Support Program for Chongqing Overseas Returnees(cx2023087)The Chongqing Technology Innovation and Application Development Project(No.2024TIAD-KPX0003).
文摘Micro-sized anatase TiO_(2) displays inferior capacity as cathode material for magnesium ion batteries because of the higher diffusion energy barrier of Mg^(2+)in anatase TiO_(2) lattice.Herein,we report that nanosized anatase TiO_(2) exposed(001)facet doubles the capacity compared to the micro-sized sample ascribed to the interfacial Mg^(2+)ion storage.First-principles calculations reveal that the diffusion energy barrier of Mg^(2+)on the(001)facet is significantly lower than those in the bulk phase and on(100)facet,and the adsorption energy of Mg^(2+)on the(001)facet is also considerably lower than that on(100)facet,which guarantees superior interfacial Mg^(2+)storage of(001)facet.Moreover,anatase TiO_(2) exposed(001)facet displays a significantly higher capacity of 312.9 mAh g^(−1) in Mg-Li dual-salt electrolyte compared to 234.3 mAh g^(−1) in Li salt electrolyte.The adsorption energies of Mg^(2+)on(001)facet are much lower than the adsorption energies of Li+on(001)facet,implying that the Mg^(2+)ion interfacial storage is more favorable.These results highlight that controlling the crystal facet of the nanocrystals effectively enhances the interfacial storage of multivalent ions.This work offers valuable guidance for the rational design of high-capacity storage systems.
文摘【背景】酪蛋白水解蛋白酶L(caseinolytic protease L,ClpL)是热休克蛋白100(heat shock protein 100,HSP100)家族成员,参与多种细胞内生物学过程包括应激耐受反应、长期存活、毒力和抗生素抗性等,在病原菌的致病过程中发挥重要作用。【目的】阐明HSP100/ClpL对猪链球菌2型(Streptococcus suis type 2)强毒株的应激耐受和毒力的影响。【方法】利用温敏自杀质粒pSET4s构建了SsClpL基因缺失株ΔclpL;利用大肠杆菌-猪链球菌穿梭质粒pSET2构建了互补株CΔclpL;比较亲本株SS2-1、ΔclpL和CΔclpL在各种应激环境(高温、氧化性应激和酸应激)和血液中的生存能力;利用小鼠感染模型和体内竞争试验评价clpL缺失前后细菌的毒力变化。【结果】clpL缺失后,SS2在各种应激环境中的生存能力明显减弱;同时在猪全血中的存活能力也显著降低;对BALB/c小鼠的致病力有所降低,在体内的定殖能力明显降低。【结论】SsClpL与猪链球菌的应激耐受和致病性密切相关。
文摘目的探析脑梗死患者髓鞘碱性蛋白(myelin basic protein,MBP)、S100钙结合蛋白B(S100 calcium-binding protein B,S100-B)水平与介入治疗后早期神经功能恶化的关联性。方法纳入2021年7月–2024年7月期间本院收治的258例脑梗死患者,采用美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分评估患者的神经功能状况,将死亡患者或介入治疗24 h后NIHSS评分增加4分及以上患者纳入早期神经功能恶化组,其余患者纳入未恶化组。测定所有患者MBP、S100-B水平,并分析其水平变化与介入治疗后神经功能恶化风险的关系。结果脑梗死患者早期神经功能恶化组血清MBP、S100-B水平高于未恶化组〔t=9.062(95%CI:2.348~3.663)、7.708(95%CI:0.221~0.375),P<0.001〕;Spearman相关性显示:恶化组血清MBP、S100-B水平与NIHSS评分增加情况呈正相关〔r=0.323(95%CI:0.095~0.542)、0.292(95%CI:0.066~0.488),P<0.05〕;分层回归分析显示:血清MBP〔比值比(odds ratio,OR)=1.996,95%CI:1.607~2.478〕、S100-B(OR=1.005,95%CI:1.003~1.007)水平是影响脑梗死患者早期神经功能恶化的危险因素(P<0.05),即使校正混杂因素后依然是其危险因素,此外入院NIHSS评分(OR=1.224,95%CI:1.142~1.310)及合并高血压(OR=2.542,95%CI:1.139~5.669)、高脂血症(OR=2.618,95%CI:1.101~6.228),其中入院NIHSS评分与MBP存在交互作用(OR=1.081,95%CI:1.034~1.130);受试者工作特征曲线显示:血清MBP、S100-B水平评估脑梗死患者早期神经功能恶化的曲线下面积分别为0.822(95%CI:0.764~0.879)、0.788(95%CI:0.724~0.853)。结论脑梗死患者介入治疗后血清MBP、S100-B水平较高与早期神经功能恶化风险相关,且对神经功能恶化风险有一定的评估价值。
基金supported by National Natural Science Foundation of China(No.11175137)
文摘A large diamond crystal up to 500 μm in diameter with a smooth （100） facet at its top has been synthesized on Mo substrate through microwave plasma chemical vapor deposition （MPCVD）. Its morphology and quality were characterized by scanning electron microscopy （SEM）, and the growth mechanism was roughly illustrated from both macroscopic and microscopic viewpoints. It was found that morphological instabilities are a major factor resulting in synthesis of large diamond crystals, moreover, high microwave power density （MPD）, high CH4 concentrations, high pressure, high substrate surface temperature and the addition of a small amount of O2 were also necessary for the synthesis of large diamond crystals.
