Heart disease(HD)is a serious widespread life-threatening disease.The heart of patients with HD fails to pump sufcient amounts of blood to the entire body.Diagnosing the occurrence of HD early and efciently may preven...Heart disease(HD)is a serious widespread life-threatening disease.The heart of patients with HD fails to pump sufcient amounts of blood to the entire body.Diagnosing the occurrence of HD early and efciently may prevent the manifestation of the debilitating effects of this disease and aid in its effective treatment.Classical methods for diagnosing HD are sometimes unreliable and insufcient in analyzing the related symptoms.As an alternative,noninvasive medical procedures based on machine learning(ML)methods provide reliable HD diagnosis and efcient prediction of HD conditions.However,the existing models of automated ML-based HD diagnostic methods cannot satisfy clinical evaluation criteria because of their inability to recognize anomalies in extracted symptoms represented as classication features from patients with HD.In this study,we propose an automated heart disease diagnosis(AHDD)system that integrates a binary convolutional neural network(CNN)with a new multi-agent feature wrapper(MAFW)model.The MAFW model consists of four software agents that operate a genetic algorithm(GA),a support vector machine(SVM),and Naïve Bayes(NB).The agents instruct the GA to perform a global search on HD features and adjust the weights of SVM and BN during initial classication.A nal tuning to CNN is then performed to ensure that the best set of features are included in HD identication.The CNN consists of ve layers that categorize patients as healthy or with HD according to the analysis of optimized HD features.We evaluate the classication performance of the proposed AHDD system via 12 common ML techniques and conventional CNN models by using across-validation technique and by assessing six evaluation criteria.The AHDD system achieves the highest accuracy of 90.1%,whereas the other ML and conventional CNN models attain only 72.3%–83.8%accuracy on average.Therefore,the AHDD system proposed herein has the highest capability to identify patients with HD.This system can be used by medical practitioners to diagnose HD efciently。展开更多
Whale optimization algorithm(WOA)is a new population-based meta-heuristic algorithm.WOA uses shrinking encircling mechanism,spiral rise,and random learning strategies to update whale’s positions.WOA has merit in term...Whale optimization algorithm(WOA)is a new population-based meta-heuristic algorithm.WOA uses shrinking encircling mechanism,spiral rise,and random learning strategies to update whale’s positions.WOA has merit in terms of simple calculation and high computational accuracy,but its convergence speed is slow and it is easy to fall into the local optimal solution.In order to overcome the shortcomings,this paper integrates adaptive neighborhood and hybrid mutation strategies into whale optimization algorithms,designs the average distance from itself to other whales as an adaptive neighborhood radius,and chooses to learn from the optimal solution in the neighborhood instead of random learning strategies.The hybrid mutation strategy is used to enhance the ability of algorithm to jump out of the local optimal solution.A new whale optimization algorithm(HMNWOA)is proposed.The proposed algorithm inherits the global search capability of the original algorithm,enhances the exploitation ability,improves the quality of the population,and thus improves the convergence speed of the algorithm.A feature selection algorithm based on binary HMNWOA is proposed.Twelve standard datasets from UCI repository test the validity of the proposed algorithm for feature selection.The experimental results show that HMNWOA is very competitive compared to the other six popular feature selection methods in improving the classification accuracy and reducing the number of features,and ensures that HMNWOA has strong search ability in the search feature space.展开更多
文摘Heart disease(HD)is a serious widespread life-threatening disease.The heart of patients with HD fails to pump sufcient amounts of blood to the entire body.Diagnosing the occurrence of HD early and efciently may prevent the manifestation of the debilitating effects of this disease and aid in its effective treatment.Classical methods for diagnosing HD are sometimes unreliable and insufcient in analyzing the related symptoms.As an alternative,noninvasive medical procedures based on machine learning(ML)methods provide reliable HD diagnosis and efcient prediction of HD conditions.However,the existing models of automated ML-based HD diagnostic methods cannot satisfy clinical evaluation criteria because of their inability to recognize anomalies in extracted symptoms represented as classication features from patients with HD.In this study,we propose an automated heart disease diagnosis(AHDD)system that integrates a binary convolutional neural network(CNN)with a new multi-agent feature wrapper(MAFW)model.The MAFW model consists of four software agents that operate a genetic algorithm(GA),a support vector machine(SVM),and Naïve Bayes(NB).The agents instruct the GA to perform a global search on HD features and adjust the weights of SVM and BN during initial classication.A nal tuning to CNN is then performed to ensure that the best set of features are included in HD identication.The CNN consists of ve layers that categorize patients as healthy or with HD according to the analysis of optimized HD features.We evaluate the classication performance of the proposed AHDD system via 12 common ML techniques and conventional CNN models by using across-validation technique and by assessing six evaluation criteria.The AHDD system achieves the highest accuracy of 90.1%,whereas the other ML and conventional CNN models attain only 72.3%–83.8%accuracy on average.Therefore,the AHDD system proposed herein has the highest capability to identify patients with HD.This system can be used by medical practitioners to diagnose HD efciently。
基金This work was supported by the National Natural Science Foundation of China(Grant No.2017YFC0403605 and No.11601419).
文摘Whale optimization algorithm(WOA)is a new population-based meta-heuristic algorithm.WOA uses shrinking encircling mechanism,spiral rise,and random learning strategies to update whale’s positions.WOA has merit in terms of simple calculation and high computational accuracy,but its convergence speed is slow and it is easy to fall into the local optimal solution.In order to overcome the shortcomings,this paper integrates adaptive neighborhood and hybrid mutation strategies into whale optimization algorithms,designs the average distance from itself to other whales as an adaptive neighborhood radius,and chooses to learn from the optimal solution in the neighborhood instead of random learning strategies.The hybrid mutation strategy is used to enhance the ability of algorithm to jump out of the local optimal solution.A new whale optimization algorithm(HMNWOA)is proposed.The proposed algorithm inherits the global search capability of the original algorithm,enhances the exploitation ability,improves the quality of the population,and thus improves the convergence speed of the algorithm.A feature selection algorithm based on binary HMNWOA is proposed.Twelve standard datasets from UCI repository test the validity of the proposed algorithm for feature selection.The experimental results show that HMNWOA is very competitive compared to the other six popular feature selection methods in improving the classification accuracy and reducing the number of features,and ensures that HMNWOA has strong search ability in the search feature space.
