目的分析2008—2024年老年性肌少症与线粒体相关性研究的现状、热点及发展趋势,为该领域的后续研究提供参考。方法检索2008年1月1日至2024年12月31日Web of Science核心合集数据库收录的老年性肌少症与线粒体相关性研究的文献,使用R 4....目的分析2008—2024年老年性肌少症与线粒体相关性研究的现状、热点及发展趋势,为该领域的后续研究提供参考。方法检索2008年1月1日至2024年12月31日Web of Science核心合集数据库收录的老年性肌少症与线粒体相关性研究的文献,使用R 4.2.0软件的Bibliometrix包对发文国家、合作网络、作者、机构、期刊、高被引文献、关键词和文献被引频次进行定量和可视化分析,并运用H指数分析作者的学术影响力。结果共纳入1219篇文献,2008—2024年发文量总体呈上升趋势。累计发文量排名前三位的国家分别是美国、中国和意大利;发文量排名前三位的期刊分别为Journal of Cachexia,Sarcopenia and Muscle、International Journal of Molecular Sciences和Experimental Gerontology;H指数排名前六位的作者分别为Marzettie E、Calvani R、Picca A、Van Remmen H、Leeuwenbugh C和Bernabel R;被引频次最高的文献是“Sarcopenia:agingrelated loss of muscle mass and function”;出现频次排名前五的关键词分别为skeletalmuscle、sarcopenia、oxidative stress、exercise和expression。结论老年性肌少症与线粒体相关性研究领域呈现良好的发展态势。未来需加强跨国家、跨机构和跨学科合作,可重点关注线粒体融合蛋白等对线粒体功能的影响,以及饮食和运动对老年性肌少症的干预作用等方面的探索。展开更多
BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as exp...BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.展开更多
文摘目的分析2008—2024年老年性肌少症与线粒体相关性研究的现状、热点及发展趋势,为该领域的后续研究提供参考。方法检索2008年1月1日至2024年12月31日Web of Science核心合集数据库收录的老年性肌少症与线粒体相关性研究的文献,使用R 4.2.0软件的Bibliometrix包对发文国家、合作网络、作者、机构、期刊、高被引文献、关键词和文献被引频次进行定量和可视化分析,并运用H指数分析作者的学术影响力。结果共纳入1219篇文献,2008—2024年发文量总体呈上升趋势。累计发文量排名前三位的国家分别是美国、中国和意大利;发文量排名前三位的期刊分别为Journal of Cachexia,Sarcopenia and Muscle、International Journal of Molecular Sciences和Experimental Gerontology;H指数排名前六位的作者分别为Marzettie E、Calvani R、Picca A、Van Remmen H、Leeuwenbugh C和Bernabel R;被引频次最高的文献是“Sarcopenia:agingrelated loss of muscle mass and function”;出现频次排名前五的关键词分别为skeletalmuscle、sarcopenia、oxidative stress、exercise和expression。结论老年性肌少症与线粒体相关性研究领域呈现良好的发展态势。未来需加强跨国家、跨机构和跨学科合作,可重点关注线粒体融合蛋白等对线粒体功能的影响,以及饮食和运动对老年性肌少症的干预作用等方面的探索。
文摘BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.
