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Traveling wave effect on the seismic response of a steel arch bridge subjected to near fault ground motions 被引量:12
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作者 徐艳 George C Lee 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2007年第3期245-257,共13页
In the 1990s, several major earthquakes occurred throughout the world, with a common observation that near fault ground motion (NFGM) characteristics had a distinct impact on causing damage to civil engineering stru... In the 1990s, several major earthquakes occurred throughout the world, with a common observation that near fault ground motion (NFGM) characteristics had a distinct impact on causing damage to civil engineering structures that could not be predicted by using far field ground motions. Since then, seismic responses of structures under NFGMs have been extensively examined, with most of the studies focusing on structures with relatively short fundamental periods, where the traveling wave effect does not need to be considered. However, for long span bridges, especially arch bridges, the traveling wave (only time delay considered) effect may be very distinct and is therefore important. In this paper, the results from a case study on the seismic response of a steel arch bridge under selected NFGMs is presented by considering the traveling wave effect with variable apparent velocities. The effects of fling step and long period pulses of NFGMs on the seismic responses of the arch bridge are also discussed. 展开更多
关键词 traveling wave effect arch bridge near fault ground motion fling step long period pulses
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Wave effects on the retrieved wind field from the advanced scatterometer(ASCAT) 被引量:1
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作者 REN Lin YANG Jingsong +2 位作者 ZHENG Gang WANG Juan CHEN Peng 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2015年第1期79-84,共6页
To improve retrieval accuracy, this paper studies wave effects on retrieved wind field from a scatterometer. First, the advanced scatterometer (ASCAT) data and buoy data of the National Data Buoy Center (NDBC) are... To improve retrieval accuracy, this paper studies wave effects on retrieved wind field from a scatterometer. First, the advanced scatterometer (ASCAT) data and buoy data of the National Data Buoy Center (NDBC) are collocated. Buoy wind speed is converted into neutral wind at 10 m height. Then, ASCAT data are com- pared with the buoy data for the wind speed and direction. Subsequently, the errors between the ASCAT and the buoy wind as a function of each wave parameter are used to analyze the wave effects. Wave param- eters include dominant wave period (dpd), significant wave height (swh), average wave period (apd) and the angle between the dominant wave direction (dwd) and the wind direction. Collocated data are divided into sub-datasets according to the different intervals of each wave parameter. A root mean square error (RMSE) for the wind speed and a mean absolute error (MAE) for the wind direction are calculated from the sub-datasets, which are considered as the function of wave parameters. Finally, optimal wave conditions on wind retrieved from the ASCAT are determined based on the error analyses. The results show the ocean wave parameters have correlative relationships with the RMSE of the retrieved wind speed and the MAE of the retrieved wind direction. The optimal wave conditions are presented in terms of dpd, swh, apd and angle. 展开更多
关键词 advanced scatterometer ASCAT wind field wave effects wave parameters
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Analysis on influence of seismic travelling wave effect on semi-active control for long-span rigid-continuous bridge 被引量:1
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作者 亓兴军 李小军 周国良 《Acta Seismologica Sinica(English Edition)》 EI CSCD 2006年第2期199-206,共8页
The analysis approach of semi-active control for long-span rigid-continuous bridge under seismic travelling wave input is established. Magnetorheological dampers are set on the positions of the bridge beatings. The se... The analysis approach of semi-active control for long-span rigid-continuous bridge under seismic travelling wave input is established. Magnetorheological dampers are set on the positions of the bridge beatings. The semi-active control calculation and analysis are performed for a five-span rigid-continuous bridge under seismic travelling waves with different apparent surface velocities. The results indicate that travelling wave effect remarkably influences the uncontrolled seismic responses, the semi-active control seismic responses and vibration control effects for the long-span rigid-continuous bridge. It is disadvantageous to the responses of the beams and the piers under the travelling wave input with lower apparent surface velocity, and travelling wave effect can decrease the vibration control effects evidently. Therefore, the travelling wave effect should be considered for the selection of the parameter values of semi-active control system in order to get the designing control effect. 展开更多
关键词 travelling wave effect semi-active control long-span rigid-continuous bridge magnetorheoiogicai damper
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Elimination of Wind Wave Effects on Sub-Bottom Profiler Record
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作者 刘秀娟 高抒 杨旸 《China Ocean Engineering》 SCIE EI 2007年第2期355-362,共8页
With the presence of wind waves, the swaying of survey vessel may effect the quality of sub-bottom profiler records and, therefore, it is necessary to correct the distortions induced by wave action. A major issue is t... With the presence of wind waves, the swaying of survey vessel may effect the quality of sub-bottom profiler records and, therefore, it is necessary to correct the distortions induced by wave action. A major issue is to distinguish wind wave effect and real bedforms such as sand waves. In this paper, a bandstop filter is designed according to the frequency features of wind wave effect to treat the distortion of seabed topography by wind waves. The technique is used to correct the sub-bottom profile in order to eliminate the wave-induced distortions for the sub-bottom profile records from the Yangtze Estuary. This study shows that the undulate seabed record is resulted from wave action, rather than the presence of sand waves, and the filtration technique helps to eliminate the wave effect and recover the real morphology of seabed and the sediment sequence underneath. In addition, a method for data processing is proposed for the case that the record indeed represents a combination of wave effects and real bedforms. 展开更多
关键词 sub-bottom profiler wind wave effect filtering method Yangtze Estuary
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Electron Momentum Spectroscopy of Valence Orbitals of Cyclopentene:Nuclear Dynamics and Distorted Wave Effect
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作者 Zhao-hui Liu En-liang Wang +3 位作者 Ya-guo Tang Shan-shan Niu Xu Shan Xiang-jun Chen 《Chinese Journal of Chemical Physics》 SCIE EI CAS CSCD 2022年第5期783-796,I0012,共15页
We report a measurement of electron momentum distributions of valence orbitals of cyclopentene employing symmetric noncoplanar(e,2e)kinematics at impact energies of 1200 and 1600 eV plus the binding energy.Experimenta... We report a measurement of electron momentum distributions of valence orbitals of cyclopentene employing symmetric noncoplanar(e,2e)kinematics at impact energies of 1200 and 1600 eV plus the binding energy.Experimental momentum profiles for individual ionization bands are obtained and compared with theoretical calculations considering nuclear dynamics by harmonic analytical quantum mechanical and thermal sampling molecular dynamics approaches.The results demonstrate that molecular vibrational motions including ring-puckering of this flexible cyclic molecule have obvious influences on the electron momentum profiles for the outer valence orbitals,especially in the low momentum region.Forπ^(*)-like molecular orbitals 3a′′,2a′′,and 3a′,the impact-energy dependence of the experimental momentum profiles indicates a distorted wave effect. 展开更多
关键词 Electron momentum profile Nuclear dynamics Ring-puckering Distorted wave effect
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Relativistic and distorted wave effects on Xe 4d electron momentum distributions
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作者 赵敏福 单旭 +1 位作者 牛姗姗 陈向军 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第9期133-136,共4页
The relativistic and distorted wave effects are investigated for the electron momentum distributions of Xe 4d electrons.The theoretical results show good agreements with the experimental data measured previously with ... The relativistic and distorted wave effects are investigated for the electron momentum distributions of Xe 4d electrons.The theoretical results show good agreements with the experimental data measured previously with electron momentum spectroscopy. The distorted wave effect and the relativistic effect are found to play important roles in the low and high momentum regions, respectively. 展开更多
关键词 relativistic effect distorted wave effect electron momentum distributions
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One-dimensional wave theory analysis of factors and characteristics influencing errors in two-wave method data processing in SHPB 被引量:1
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作者 Minghui Ma Guangfa Gao 《Acta Mechanica Sinica》 2025年第1期128-140,共13页
A simplified calculation of the specimen’s stress-strain curve is generally conducted using the two-wave method by the split Hopkinson pressure bar(SHPB),which aligns the onset of the transmitted and reflected waves.... A simplified calculation of the specimen’s stress-strain curve is generally conducted using the two-wave method by the split Hopkinson pressure bar(SHPB),which aligns the onset of the transmitted and reflected waves.However,this approach neglects the travel time of elastic waves within the specimen.Considering the travel time of elastic waves,this study quantitatively investigates the error characteristics and patterns of stress,strain,and strain rate in the specimen under different conditions using the theoretical two-wave method,and compares the results with those obtained using the onset-aligned twowave method.The study reveals that the stress-time curves derived from the theoretical two-wave method are lower than the actual stress curves,whereas those obtained from the onset-aligned two-wave method are consistently higher than the actual stress curves,with the stress deviation approximating a constant value when the dimensionless time exceeds 2.0.The starting point of the stress-strain curves obtained by the theoretical two-wave method is not zero but a point on the strain axis,whereas the onset-aligned two-wave method always starts at zero.However,the slopes of the stress-strain curves obtained by both methods differ from the actual Young’s modulus of the material,and functional relationships between the slopes and the actual Young’s modulus are provided.This research offers theoretical guidance for the refined design of SHPB experiments and the accurate processing of data. 展开更多
关键词 SHPB Stress wave effect Assumption of stress uniformity Dynamic stress-strain curve
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基于D-Wave Advantage的量子计算实用化SPN结构对称密码攻击研究 被引量:1
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作者 裴植 洪春雷 +2 位作者 王启迪 胡巧云 王潮 《计算机学报》 北大核心 2025年第1期234-248,共15页
截至2023年,谷歌的量子霸权芯片Sycamore尚不能用于密码攻击。量子计算在理论上对公钥密码有致命性威胁,但对对称密码影响甚微,目前业内已经从缩减版密码算法开始积极探索对称密码的量子攻击。SPN结构是对称密码算法中的一种代表性结构... 截至2023年,谷歌的量子霸权芯片Sycamore尚不能用于密码攻击。量子计算在理论上对公钥密码有致命性威胁,但对对称密码影响甚微,目前业内已经从缩减版密码算法开始积极探索对称密码的量子攻击。SPN结构是对称密码算法中的一种代表性结构,目前基于真实量子计算机的各类量子算法均未能对该结构未经缩减的全规模密码算法进行攻击。基于量子退火算法独有的隧穿效应,使得该算法有利于科学问题的指数级解空间搜索,可将其视为一类具有全局寻优能力的人工智能算法。受传统密码分析方法的影响,本文提出一种对称密码攻击架构:量子退火耦合传统数学方法密码攻击的新型计算架构——QuCMC(Quantum Annealing-Classical Mixed Cryptanalysis)。基于该架构,首先利用可分性刻画SPN结构对称密码算法的线性层和非线性层传播规律,将区分器搜索问题转化为MILP模型求解问题。进一步将MILP模型转化为D-Wave CQM模型,在求解该模型的过程中利用量子波动产生的量子隧穿效应跳出传统智能算法极易陷入的局部亚优解,获得更优的解,即攻击目标对称密码算法的积分区分器。本文使用D-Wave Advantage量子计算机攻击了PRESENT、GIFT-64、RECTANGLE三种SPN结构代表算法,均成功搜索到最长9轮的积分区分器。并且实验结果表明,量子退火算法在跳出局部亚优解能力与降低求解时间两个方面,均优于经典启发式全局寻优算法模拟退火。本研究首次成功利用真实量子计算机对多种全规模SPN结构对称密码算法完成了攻击,攻击效果与传统数学方法持平。 展开更多
关键词 对称密码 量子计算 量子退火 D-wave量子计算机 量子隧穿效应
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Optimizing basis wave functions in the generator coordinate method for microscopic cluster models (Ⅰ)
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作者 Yi‑Fan Liu Bo Zhou Yu‑Gang Ma 《Nuclear Science and Techniques》 2025年第10期183-191,共9页
We employed random distributions and gradient descent methods for the Generator Coordinate Method(GCM)to identify effective basis wave functions,taking halo nuclei ^(6)He and ^(6)Li as examples.By comparing the ground... We employed random distributions and gradient descent methods for the Generator Coordinate Method(GCM)to identify effective basis wave functions,taking halo nuclei ^(6)He and ^(6)Li as examples.By comparing the ground state(0^(+))energy of ^(6)He and the excited state(0^(+))energy of 6 Li calculated with various random distributions and manually selected generation coordinates,we found that the heavy tail characteristic of the logistic distribution better describes the features of the halo nuclei.Subsequently,the Adam algorithm from machine learning was applied to optimize the basis wave functions,indicating that a limited number of basis wave functions can approximate the converged values.These results offer some empirical insights for selecting basis wave functions and contribute to the broader application of machine learning methods in predicting effective basis wave functions. 展开更多
关键词 Generator Coordinate Method effective basis wave functions Nuclear cluster model Machine learning Halo nuclei
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Propagation Dynamics of Forced Pulsating Waves for a Time Periodic Lotka-Volterra Cooperative System with Nonlocal Effects in Shifting Habitats
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作者 Zewen Gong 《Journal of Applied Mathematics and Physics》 2024年第10期3402-3421,共20页
In this paper, we will concern the existence, asymptotic behaviors and stability of forced pulsating waves for a Lotka-Volterra cooperative system with nonlocal effects under shifting habitats. By using the alternativ... In this paper, we will concern the existence, asymptotic behaviors and stability of forced pulsating waves for a Lotka-Volterra cooperative system with nonlocal effects under shifting habitats. By using the alternatively-coupling upper-lower solution method, we establish the existence of forced pulsating waves, as long as the shifting speed falls in a finite interval where the endpoints are obtained from KPP-Fisher speeds. The asymptotic behaviors of the forced pulsating waves are derived. Finally, with proper initial, the stability of the forced pulsating waves is studied by the squeezing technique based on the comparison principle. 展开更多
关键词 Nonlocal effects Time Periodic Lotka-Volterra System Forced Pulsating waves Shifting Habitats
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Effects of Irregular Wave Groups on Pile Forces
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作者 Yang, Zhengji Zuo, Qihua 《China Ocean Engineering》 SCIE EI 1991年第2期175-190,共16页
The wave forces on 1,2 and 4 vertical circular piles under the action of several wave trains of the same wave parameters, such as Hs Tp and Mo, but different wave group factors GF are measured in the laboratory. After... The wave forces on 1,2 and 4 vertical circular piles under the action of several wave trains of the same wave parameters, such as Hs Tp and Mo, but different wave group factors GF are measured in the laboratory. After comparing these forces, it may be concluded that the mean and significant wave forces are almost of no difference for the wave trains with different GF. When GF is larger, the one-tenth of the wave force extreme is slightly increased and the maximum wave force is much larger than the ones with smaller GF, to which attention must be paid in engineering practice. 展开更多
关键词 Water waves wave effects
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Topographic effects on seismic response of long-span rigid-frame bridge under SV seismic wave
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作者 王蕾 赵成刚 屈铁军 《Acta Seismologica Sinica(English Edition)》 CSCD 2008年第3期311-318,333,共9页
Seismic ground motions of two neighboring mountains and the free surface between them are calculated under the SV seismic waves with three different incident angles. The results are then taken as the inputs of multi-p... Seismic ground motions of two neighboring mountains and the free surface between them are calculated under the SV seismic waves with three different incident angles. The results are then taken as the inputs of multi-point seismic excitations for the foundation of a long-span bridge built over the valley in the analysis considering the integrated influence of traveling wave and topography. On the basis of a dynamic analytical method, a finite element model is created for the seismic responses of a four-span rigid-frame bridge of 440 m. The pier-top displacement and the pier-bottom internal force of the bridge are calculated. Then the results are compared with those considering traveling-wave effect only. The conclusions can serve as a seismic design reference for the structures located on the complex mountain topography. 展开更多
关键词 traveling-wave effect topographic effect multi-point excitation rigid-frame bridge seismic response
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An analytical solution to the scattering of cylindrical SH waves by a partially filled semi-circular alluvial valley: near-source site effects 被引量:9
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作者 Zhang Ning Gao Yufeng +1 位作者 Yang Jie Xu Changjie 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2015年第2期189-201,共13页
The earth’s surface irregularities can substantially affect seismic waves and induce amplifi cations of ground motions. This study investigates whether and how the source characteristics affect the site amplifi catio... The earth’s surface irregularities can substantially affect seismic waves and induce amplifi cations of ground motions. This study investigates whether and how the source characteristics affect the site amplifi cation effects. An analytical model of a line source of cylindrical waves impinging on an alluvial valley is proposed to link the source and site. The analytical solution to this problem proves one aspect of the strong effect of source on site amplifi cation, i.e., the wave curvature effect. It is found that the site amplifi cation depends on the source location, especially under conditions of a small source-to-site distance. Whether the displacement is amplifi ed or reduced and the size of the amplifi cation or reduction may be determined by the location of the source. It is suggested that traditional studies of site responses, which usually ignore the source effect, should be further improved by combining the source with site effects. 展开更多
关键词 site effects source effects wave function expansio
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Effective wave identification and interference analysis of the seismic reflection method in mines 被引量:1
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作者 HU Yun-bing WU Yan-qing KANG Hou-qing 《Journal of Coal Science & Engineering(China)》 2009年第3期308-312,共5页
Through discussion of the time-distance curve characteristics of the direct waveand from the front,side and rear of the reflection waves of the seismic reflection methodfor advanced exploration in mines,and analysis o... Through discussion of the time-distance curve characteristics of the direct waveand from the front,side and rear of the reflection waves of the seismic reflection methodfor advanced exploration in mines,and analysis of several major interference waves inmines,the differences in time-distance curve,frequency,apparent velocity between theeffective wave and interference wave in the seismic reflection method for advanced explorationare obtained.According to the differences,the effective wave is extracted andthe interference wave is filtered and the system's precision and accuracy is improved. 展开更多
关键词 INTERFERENCE seismic reflection method MINE effective wave
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Laboratory Research on Effective Test Area of Short-Crested Waves Generated by Two-Sided Segmented Wavemakers 被引量:1
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作者 李俊 陈刚 +1 位作者 杨建民 彭涛 《China Ocean Engineering》 SCIE EI CSCD 2014年第2期181-192,共12页
The size and shape of the effective test area are crucial to consider when short-crested waves are created by segmented wavemakers. The range of the effective test area of short-crested waves simulated by two-sided se... The size and shape of the effective test area are crucial to consider when short-crested waves are created by segmented wavemakers. The range of the effective test area of short-crested waves simulated by two-sided segmented wavemakers is analyzed in this paper. The experimental investigation on the wave field distribution of short-crested waves generated by two-sided segmented wavemakers is conducted by using an array of wave gauges. Wave spectra and directional spreading function are analyzed and the results show that when the main direction is at a certain angle with the normal line of wave generators, the wave field of 3D short-crested waves generated by two-sided segmented wavemakers has good spatial uniformity within the model test area. The effective test area can provide good wave environments for seakeeping model tests of various ocean engineering structures in the deep ocean engineering basin. 展开更多
关键词 wave simulation 3D short-crested wave effective test area two-sided segmented wavemakers
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Density waves in a lattice hydrodynamic traffic flow model with the anticipation effect 被引量:2
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作者 赵敏 孙棣华 田川 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第4期619-624,共6页
By introducing the traffic anticipation effect in the real world into the original lattice hydrodynamic model, we present a new anticipation effect lattice hydrodynamic (AELH) model, and obtain the linear stability ... By introducing the traffic anticipation effect in the real world into the original lattice hydrodynamic model, we present a new anticipation effect lattice hydrodynamic (AELH) model, and obtain the linear stability condition of the model by applying the linear stability theory. Through nonlinear analysis, we derive the Burgers equation and Korteweg-de Vries (KdV) equation, to describe the propagating behaviour of traffic density waves in the stable and the metastable regions, respectively. The good agreement between simulation results and analytical results shows that the stability of traffic flow can be enhanced when the anticipation effect is considered. 展开更多
关键词 traffic flow lattice hydrodynamic model density waves anticipation effect
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Geometrical Evaluation on the Viscous Effect of Point-Absorber Wave-Energy Converters 被引量:5
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作者 CHEN Zhong-fei ZHOU Bin-zhen +3 位作者 ZHANG Liang ZHANG Wan-chao WANG Shu-qi ZANG Jun 《China Ocean Engineering》 SCIE EI CSCD 2018年第4期443-452,共10页
The fluid viscosity is known to have a significant effect on the hydrodynamic characteristics which are linked to the power conversion ability of the wave energy converter(WEC). To overcome the disadvantages of case-b... The fluid viscosity is known to have a significant effect on the hydrodynamic characteristics which are linked to the power conversion ability of the wave energy converter(WEC). To overcome the disadvantages of case-by-case study through the experiments and numerical computations employed by the former researches, the viscous effect is studied comprehensively for multiple geometries in the present paper. The viscous effect is expressed as the viscous added mass and damping solved by the free-decay method. The computational fluid dynamics(CFD) method is employed for the calculation of the motion and flow field around the floater. The diameter to draft ratio and bottom shape are considered for the geometrical evaluation on the viscous effect. The results show that a slenderer floater presents a stronger viscous effect. Through the comparisons of the floaters with four different bottom shapes, the conical bottom is recommended in terms of low viscous effect and simple geometry for manufacture. A viscous correction formula for a series of cylindrical floaters is put forward, for the first time, to help the engineering design of outer-floaters of point-absorber WECs. 展开更多
关键词 viscous effect wave energy convertor multiple geometries viscous correction CFD
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A STUDY ON THE EFFECT OF RADIAL INERTIA ON THE ELASTO-PLASTIC COMBINED STRESS WAVE PROPAGATION IN THIN-WALLED TUBES 被引量:2
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作者 Li Yongchi Huang Chengyi Yuan Fuping Jin Yongmei 《Acta Mechanica Solida Sinica》 SCIE EI 2001年第1期58-66,共9页
An in-depth analysis of propagation characteristics ofelasto-plastic combined stress waves in circular thin-walled tubeshas been made. In obtaining the simple-wave solution, however, mostresearches have ignored the in... An in-depth analysis of propagation characteristics ofelasto-plastic combined stress waves in circular thin-walled tubeshas been made. In obtaining the simple-wave solution, however, mostresearches have ignored the influence of the circumferential stressrelated to the radial inertial ef- fect in the tubes. In this paperthe incremental elasto-plastic constitutive relations which areconve- nient for dynamic numerical analysis are adopted, and thefinite-difference method is used to study the evolution adpropagation of elasto-plastic combined stress waves in a thin-walledtube with the radial inertial effect of the tube considered. Thecalculation results are compared with those obtained when the radialinertial effect is not considered. The calculation results show thatthe radial inertial effect of a tube has a fairly great influence onthe propagation of elasto-plastic combined stress waves. 展开更多
关键词 circular thin-walled tube elasto-plastic combined stress waves radialinertial effect
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Modified KdV equation for solitary Rossby waves with β effect in barotropic fluids 被引量:10
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作者 宋健 杨联贵 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第7期2873-2877,共5页
This paper uses the weakly nonlinear method and perturbation method to deal with the quasi-geostrophic vorticity equation,and the modified Korteweg-de Vries(mKdV) equations describing the evolution of the amplitude ... This paper uses the weakly nonlinear method and perturbation method to deal with the quasi-geostrophic vorticity equation,and the modified Korteweg-de Vries(mKdV) equations describing the evolution of the amplitude of solitary Rossby waves as the change of Rossby parameter β(у) with latitude у is obtained. 展开更多
关键词 nonlinear Rossby waves mKdV equation β effect perturbation method
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Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice 被引量:2
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作者 SONG Quan Quan NIN Jing Ping +3 位作者 ZHANG Shu Yu LIANG Ting Ting ZHOU Ji FENG Shan Shan 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第10期757-768,共12页
Objective To discuss the cardiac toxicities of a heat waves and ozone exposure on cardiovascular diseases(CVDs) and explore a possible mechanism. Methods The incidence of ozone exposure combined with heat wave was s... Objective To discuss the cardiac toxicities of a heat waves and ozone exposure on cardiovascular diseases(CVDs) and explore a possible mechanism. Methods The incidence of ozone exposure combined with heat wave was simulated in the Shanghai Meteorological and Environmental Animal Exposure System(Shanghai-METAS). A total of 64 Apo E-/-mice, matched by weight, were randomly divided into 8 groups and exposed to heat wave conditions or ozone. The levels of creatine kinase(CK), D-lactate dehydrogenase(D-LDH), intercellular adhesion molecule 1(sICAM-1), tumor necrosis factor alpha(TNF-α), nitric oxide(NO), endothelin-1(ET-1), D-dimer(D2 D), plasminogen activator inhibitor-1(PAI-1) and blood lipid in plasma and heat shock protein-60(HSP60), hypoxia inducible factor 1 alpha(HIF-1α), interleukin-6(IL-6), C-reactive protein(CRP), superoxide dismutase(SOD), and malondialdehyde(MDA) in hearts were measured after exposure. Results The levels of all indicators, except for SOD, increased with the ozone-only exposure. However, cardiac damage was most significant when the heat wave conditions were combined with severe ozone exposure. Moreover, the levels of CK, D-LDH, NO, PAI-1, sICAM-1, and TNF-α in plasma increased significantly(P 〈 0.05), and the contents of HSP60, HIF-1α, CRP, and MDA in hearts increased considerably(P 〈 0.05), but the activity of SOD decreased significantly. In addition, the levels of four blood lipid items remarkably increased(except the level of HDL-C which decreased significantly) with ozone exposure. Conclusion A short-term exposure to a heat wave and ozone causes severe toxic effects on the heart. Cardiac damage was most significant under combined heat wave and severe ozone exposure simulations. 展开更多
关键词 Heat wave OZONE Damaging effects Cardiovascular disease Atherosclerosis mice Mechanism
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