Leontopodium alpinum is a traditional alpine medicinal plant,is extensively used in Tibetan and Mongolian medicine.Its applicability in managing febrile epidemics and respiratory conditions requires deeper study,espec...Leontopodium alpinum is a traditional alpine medicinal plant,is extensively used in Tibetan and Mongolian medicine.Its applicability in managing febrile epidemics and respiratory conditions requires deeper study,especially given the recurring threat of infectious diseases.This study uses bibliometric analysis to examine the current state and trends in Leontopodium alpinum research,integrates scattered information,and suggests pathways for subsequent investigation.This study retrieved Chinese literature from the China National Knowledge Infrastructure(CNKI)platform and international literature from the Web of Science(WoS),with data collection finalized by March 2025.CiteSpace 6.3.R1 and VOSviewer 1.6.20 were used to visually analyze publication trends,keyword co-occurrence,and author collaboration networks.The analysis has found that Chinese publications rose markedly after 2003 but declined after 2019,focusing largely on chemical components–such as chlorogenic acid and volatile oils–and pharmacological activities.International output,though smaller,grew steadily,with an emphasis on compositional analysis and antioxidant effects.Keyword clustering revealed that both Chinese and global research expanded from foundational taxonomy to chemical constituents,bioactivity,and environmental adaptation.Core author and institutional analyses identified Liaoning University of Traditional Chinese Medicine and the University of Chinese Academy of Sciences as domestic leaders,while the University of Innsbruck(Austria)played a leading international role.In conclusion,this study offers the first systematic summary of research and publishing trends for Leontopodium alpinum,while also identifying key knowledge gaps.Future studies should prioritize multi-omics approaches to clarify the mechanisms of its bioactive compounds and advance clinical application.Due to its notable efficacy against febrile epidemics and respiratory diseases,expanded research is strongly recommended–particularly in light of rising infectious disease risks where this species could serve an essential role.展开更多
Cerebral or intracranial aneurysm is a leading cause of subarachnoid hemorrhage. It was initially treated with open surgical clipping but as rapid development of technology a less invasive endovascular coiling techniq...Cerebral or intracranial aneurysm is a leading cause of subarachnoid hemorrhage. It was initially treated with open surgical clipping but as rapid development of technology a less invasive endovascular coiling technique of aneurysm revolutionized the treatment. Due to tortuous anatomy of parent artery and complicated morphology and location of aneurysm there is ongoing challenge in the complete obliteration of aneurysms. To aid in the advances of treating aneurysm stent assisted endovascular coiling was introduced to give more scaffold support to parent artery and decrease events of coil protrusion from aneurysms. Many types and generation of stents were developed. One of the most recently introduced stent is low profile visualized intraluminal support (LVIS) stent. Due to its low profile nature it can be used in 0.017-inch inner diameter microcatheter and reach small and complex vessels providing high aneurysmal neck coverage which was not possible through other traditional stent. In addition, its braided design with tantalum strands and radiopaque markers make it more visible during stent placement and post procedure stent evaluation. Despite of many advantages of LVIS stent it is related to high rate of thromboembolic complications and technical complications. Aim of this review paper was to evaluate therapeutic safety, effectiveness and feasibility of LVIS stent in endovascular coil embolization of intracranial aneurysms.展开更多
The development of uranyl ion detection technology has exhibited its significance in public security and environmental fields for the radioactivity and chemical toxicity of uranyl ion.The WHO standard of uranyl ion ma...The development of uranyl ion detection technology has exhibited its significance in public security and environmental fields for the radioactivity and chemical toxicity of uranyl ion.The WHO standard of uranyl ion makes it necessary to develop highly sensitive uranyl rapid warning system in drinking water monitoring.Herein,a visualized rapid warning system for trace uranyl ion is carried out based on electrochemiluminescence(ECL) imaging technology to give an ultra-low limit of detection(LOD) and high selectivity.Amidoxime,a bi-functional group with both uranyl ion capturing and co-reactive functions,is modified on a conjugated polymer backbone with strong ECL signal to be prepared into three-in-one polymer nanoparticles(PNPs) with self-enhanced ECL property.The captured uranyl ion can enhance the ECL signal of PNPs via resonance energy transfer process to give the LOD as 0.5 ng/L,which is much lower than the known luminescent uranyl sensors.Furthermore,ECL imaging technology is introduced into realizing visualized uranyl rapid warning,and can be successfully applied on natural water samples.This study provides a novel strategy for uranyl rapid warning,and shows its potential meaning in public security and environmental fields.展开更多
This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP...This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP of scheme design prototype was first built,where thermal,structural,and multidisciplinary knowledge could be integrated for visualization.To implement visualized computing,the membership function of fuzzy decision-making was optimized using a genetic algorithm.Transient thermodynamic,structural statics,and flow field analyses were conducted,especially for glass fiber composite materials,which have the characteristics of high strength,corrosion resistance,temperature resistance,dimensional stability,and electrical insulation.An electrothermal experiment was performed by measuring the temperature and changes in temperature during RP.Infrared thermographs were obtained using thermal field measurements to determine the temperature distribution.A numerical analysis of a lightweight ribbed ergonomic artifact is presented to illustrate the VCDT.Moreover,manufacturability was verified based on a thermal-solid coupled finite element analysis.The physical experiment and practice proved that the proposed VCDT provided a robust design paradigm for a layered RP between the steady balance of electrothermal regulation and manufacturing efficacy under hybrid uncertainties.展开更多
In a Mach 3.8 wind tunnel, both instantaneous and time-averaged flow structures of different scales around a blunt double-cone with or without supersonic film cooling were visualized via nano-tracer planar laser scatt...In a Mach 3.8 wind tunnel, both instantaneous and time-averaged flow structures of different scales around a blunt double-cone with or without supersonic film cooling were visualized via nano-tracer planar laser scattering （NPLS）, which has a high spatiotemporal resolution. Three experimental cases with different injection mass flux rates were carried out. Many typical flow structures were clearly shown, such as shock waves, expansion fans, shear layers, mixing layers, and turbulent boundary layers. The analysis of two NPLS images with an interval of 5 us revealed the temporal evolution characteristics of flow structures. With matched pressures, the laminar length of the mixing layer was longer than that in the case with a larger mass flux rate, but the full covered region was shorter. Structures like K-H （Kelvin-Helmholtz） vortices were clearly seen in both flows. Without injection, the flow was similar to the supersonic flow over a backward- facing step, and the structures were relatively simpler, and there was a longer laminar region. Large scale structures such as hairpin vortices were visualized. In addition, the results were compared in part with the schlieren images captured by others under similar conditions.展开更多
To work efficiently with DSS, most users need assistance in representation conversion, i. e., translating the specific outcome from the DSS into the universal language of visual. In generally, it is much easier to und...To work efficiently with DSS, most users need assistance in representation conversion, i. e., translating the specific outcome from the DSS into the universal language of visual. In generally, it is much easier to understand the results from the DSS if they are translated into charts, maps, and other scientific displays, because visualization exploits human natural ability to recognize and understand visual pattern. In this paper we discuss the concept of visualization for DSS. AniGraftool, a software system, is introduced as an example of Visualized User Interface for DSS.展开更多
A micro-nano pore three-dimensional visualized real-time physical simulation of natural gas charging, in-situ pore-scale computation, pore network modelling, and apparent permeability evaluation theory were used to in...A micro-nano pore three-dimensional visualized real-time physical simulation of natural gas charging, in-situ pore-scale computation, pore network modelling, and apparent permeability evaluation theory were used to investigate laws of gas and water flow and their distribution, and controlling factors during the gas charging process in low-permeability(tight) sandstone reservoir. By describing features of gas-water flow and distribution and their variations in the micro-nano pore system, it is found that the gas charging in the low permeability(tight) sandstone can be divided into two stages, expansion stage and stable stage. In the expansion stage, the gas flows continuously first into large-sized pores then small-sized pores, and first into centers of the pores then edges of pores;pore-throats greater than 20 μm in radius make up the major pathway for gas charging. With the increase of charging pressure, movable water in the edges of large-sized pores and in the centers of small pores is displaced out successively. Pore-throats of 20-50 μm in radius and pore-throats less than 20 μm in radius dominate the expansion of gas charging channels at different stages of charging in turn, leading to reductions in pore-throat radius, throat length and coordination number of the pathway, which is the main increase stage of gas permeability and gas saturation. Among which, pore-throats 30-50 μm in radius control the increase pattern of gas saturation. In the stable stage, gas charging pathways have expanded to the maximum, so the pathways keep stable in pore-throat radius, throat length, and coordination number, and irreducible water remains in the pore system, the gas phase is in concentrated clusters, while the water phase is in the form of dispersed thin film, and the gas saturation and gas permeability tend stable. Connected pore-throats less than 20 μm in radius control the expansion limit of the charging pathways, the formation of stable gas-water distribution, and the maximum gas saturation. The heterogeneity of connected pore-throats affects the dynamic variations of gas phase charging and gas-water distribution. It can be concluded that the pore-throat configuration and heterogeneity of the micro-nanometer pore system control the dynamic variations of the low-permeability(tight) sandstone gas charging process and gas-water distribution features.展开更多
Purified terephthalic acid(PTA) is an important chemical raw material. P-xylene(PX) is transformed to terephthalic acid(TA) through oxidation process and TA is refined to produce PTA. The PX oxidation reaction is a co...Purified terephthalic acid(PTA) is an important chemical raw material. P-xylene(PX) is transformed to terephthalic acid(TA) through oxidation process and TA is refined to produce PTA. The PX oxidation reaction is a complex process involving three-phase reaction of gas, liquid and solid. To monitor the process and to improve the product quality, as well as to visualize the fault type clearly, a fault diagnosis method based on selforganizing map(SOM) and high dimensional feature extraction method, local tangent space alignment(LTSA),is proposed. In this method, LTSA can reduce the dimension and keep the topology information simultaneously,and SOM distinguishes various states on the output map. Monitoring results of PX oxidation reaction process indicate that the LTSA–SOM can well detect and visualize the fault type.展开更多
Knowledge of migration and retention mechanisms of elastic gel particles(EGPs)in pore-throats is essential for the effective application of EGPs as a smart sweep improvement and profile control agent for enhanced oil ...Knowledge of migration and retention mechanisms of elastic gel particles(EGPs)in pore-throats is essential for the effective application of EGPs as a smart sweep improvement and profile control agent for enhanced oil recovery(EOR).The matching coefficient(defined as the ratio of particle size to pore-throat size)is used to investigate its influence on migration,retention and profile control performance of EGPs.A 1-D continuous pore-throat visualization model(PTVM),a 2-D heterogeneous PTVM and a 3-D heterogeneous core model were constructed and used to investigate pore-scale migration,retention and controlling mechanism of migration and retention characteristics on EGPs profile control.The results of the 1-D continuous PTVM indicated that while the matching coefficient was in the optimal range(i.e.,0.20-0.32),the EGPs could not only smoothly migrate to the deeper pore-throats,but also form stable retention in the pores to resist the erosion of injected water,which was conducive to the effective indepth profile control.The results of the 2-D heterogeneous PTVM verified that the sweep efficiency in low-permeability regions could be significantly improved by in-depth migration and stable retention of EGPs in the pore-throats with an optimal matching coefficient(0.29),which was much better than that in cases with a smaller matching coefficient(0.17)or an excessive matching coefficient(0.39).Moreover,the NMR displacement experiments of 3-D heterogeneous cores were carried out to simulate the EGPs profile control in actual reservoir porous media.Saturation images and T2 spectrum curves of crude oil showed that EOR in the low-permeability layer was highest(56.1%)using EGPs profile control with an optimal matching coefficient,attributing to the in-depth migration and stable retention of EGPs.展开更多
With the social development, we are stepping into an information technology world. In such a world, our life is getting more and more diversified and rich because of e-business. E-business not only provides us conveni...With the social development, we are stepping into an information technology world. In such a world, our life is getting more and more diversified and rich because of e-business. E-business not only provides us convenience but also large amounts of business data. However, how shall we better store, manage and use these business data has become a major field being studied by e-business. With the rapid growth of data volume, the relational database system cannot meet the requirements of the current status. In this paper, focusing on the visualized analysis model of Hadoop business data, it analyzed the business data in terms of the visualized platform, database and analysis model etc. Depending on the analysis, offline-data analysis and data visualization for Hive database will be greatly improved, so that references and suggestions can be provided for the visualized analysis model of Hadoop business data.展开更多
Objective: This study visualizes and analyzes the current status, hotspots, and frontiers of cardiac rehabilitation for patients with Coronary Heart Disease (CHD) over the past decade (2012.01-2022.12), and explores t...Objective: This study visualizes and analyzes the current status, hotspots, and frontiers of cardiac rehabilitation for patients with Coronary Heart Disease (CHD) over the past decade (2012.01-2022.12), and explores the future development trend and research direction of the CR for CHD patients in China. Methods: Relevant literature was searched, screened and downloaded from the Web of Science (WOS) database, and bibliometric and visualization analyses were performed using CiteSpace VI software. Results: Through the search and screening of related literature, 2443 English articles were finally included. Among them, most of the Chinese publishers were mainly universities and had less connection with each other, while the foreign publishers were mainly universities and medical institutions in the United States and Europe, and had close connection with each other. The research content of Chinese scholars mainly focuses on the assessment of patients’ life and psychological status, as well as the assessment of cardiac function. Foreign research focuses on physical training assessment, disease perception, etc. Conclusion: Through visualizing relevant research with CiteSpace VI software in the form of a knowledge map, the research frontiers and trends in the field of cardiac rehabilitation for coronary heart disease patients in China and abroad can be discovered more intuitively. Compared with foreign research, the development of cardiac rehabilitation for coronary heart disease patients in China is relatively slow and insufficient, and institutions lack cooperation. In the future, China should accelerate the connection between regions in the field of cardiac rehabilitation and develop a cardiac rehabilitation model suitable for coronary heart disease patients in China with its own characteristics.展开更多
The 2020 TKK Science Award in I Life Sciences went to CAS member SHI Yigong,a distinguished structural biologist,for his achievements in:elucidating the yeast and human splicing cycle in atomic detail,which allows us ...The 2020 TKK Science Award in I Life Sciences went to CAS member SHI Yigong,a distinguished structural biologist,for his achievements in:elucidating the yeast and human splicing cycle in atomic detail,which allows us to visually appreciate the dynamic process of the supermolecular machinery of spliceosome performing molecular surgery on the chain of a pre-message RNA(pre-mRNA)to give rise to a mature mRNA.展开更多
Temporary plugging and diversion fracturing(TPDF)is widely used to promote the uniform and complex distribution of multi-clustered hydraulic fractures(HFs)in a horizontal well of the unconventional formations.However,...Temporary plugging and diversion fracturing(TPDF)is widely used to promote the uniform and complex distribution of multi-clustered hydraulic fractures(HFs)in a horizontal well of the unconventional formations.However,the migration behavior of temporary plugging agent(TPA),as a function of the concentration and particle size of TPA and cluster-perforation numbers,etc.,determining the effectiveness of this technique,remains unclear.Therefore,this study conducted innovatively a series of TPDF simulation experiments on transparent polymethyl methacrylate(PMMA)specimens(cubic block of 30 cm×30 cm×30 cm)to explore visually the migration behavior of TPA in multi-clustered HFs in a horizontal well.A laboratory hydraulic sandblasting perforation completion technique was implemented to simulate the multi-cluster perforations.All the distributions of wellbore,perforations,HFs,and TPA can be seen clearly inside the PMMA specimen post the experiment.The results show that there are four characteristic plugging positions for the TPA:mouth of HF,middle of HF,tip of HF,and the intersection of HFs.Small particle size TPA tends to migrate to the fracture tip for plugging,while large particle size TPA tends to plug at the fracture mouth.The migration of the TPA is influenced obviously by the morphology of the fracture wall.A smooth fracture wall is conducive to the migration of the TPA to the far end of HFs,but not conducive to generating the plugging zone and HF diversion.In contrast,a"leaf vein"fracture of rough wall is conducive to generating the plugging layer and the diversion of HFs,but not conducive to the migration of the TPA to the far end of HFs.The migration ability of TPA in a"shell"pattern is intermediate between the two above cases.Increasing TPA concentration can encourage TPA to migrate more quickly to the characteristic plugging position,and thereby to promote the creation of effective plugging and subsequently the multi-stage diversion of the HFs.Nevertheless,excessive concentration may cause the TPA to settle prematurely,affecting the propagation of the HFs to the far end.Increasing the number of clusters to a certain extent can encourage TPA to migrate into the HFs and form plugging,and promote the diversion.An evaluation system for the migration ability of granular TPA has been established,and it was calculated that when there is no plugging expectation target,the comprehensive migration ability of small particle size TPA is stronger than that of large particle size TPA.This research provides theoretical foundation for the optimization of temporary plugging parameters.展开更多
Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research o...Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.展开更多
气候变化和人类活动对水文循环产生了显著影响,尤其是在干旱半干旱区.为探究变化环境下典型半干旱生态脆弱区毛乌素沙地水循环演变特征,利用WEP-L(water and energy transfer processes in large river basin)地表水模型和Visual MODFLO...气候变化和人类活动对水文循环产生了显著影响,尤其是在干旱半干旱区.为探究变化环境下典型半干旱生态脆弱区毛乌素沙地水循环演变特征,利用WEP-L(water and energy transfer processes in large river basin)地表水模型和Visual MODFLOW(visual modular finite difference groundwater flow)地下水模型对毛乌素沙地水循环过程进行分布式模拟,基于白家川水文站实测月径流量和监测井地下水位数据进行模型参数率定与验证.结果表明,地表水模型率定期和验证期的模拟月径流量和实测月径流量的R2都在0.5以上,模拟的监测井地下水位和实测地下水位趋势较为一致,相关系数达到0.56以上.采用偏差校正的CMIP6多模式集合气候变化情景及当地取用水情景驱动地表水-地下水耦合模型,量化了变化环境下毛乌素沙地2021-2040年关键水循环要素变化特征.结果表明,未来情景下毛乌素沙地年降水量和年蒸散发量的平均增幅分别为8.0%和7.4%,年径流深呈现逐渐减少的趋势,2040年末地下水位相较于2021年末下降了约1 m.未来2种用水情景下区域地下水总补给量与排泄量的差值分别为-1.82亿、-0.97亿m^(3)·a^(-1),地表径流总量与地表用水量的差值分别为1.83亿、2.29亿m^(3)·a^(-1),地下水资源开发利用将面临更大挑战.研究成果可为毛乌素沙地区域水资源规划与管理提供科学支撑.展开更多
基金supported by the National Key R&D Program of China:Intergovernmental Cooperation in International Science and Technology Innovation(2022YFE0119300)Mongolian Foundation for Science and Technology(MFST-CHN2022/277 and MFST 2022/176)Science and Technology Foundation,Ministry of Environment and Tourism of Mongolia(20BB11ShT3030).
文摘Leontopodium alpinum is a traditional alpine medicinal plant,is extensively used in Tibetan and Mongolian medicine.Its applicability in managing febrile epidemics and respiratory conditions requires deeper study,especially given the recurring threat of infectious diseases.This study uses bibliometric analysis to examine the current state and trends in Leontopodium alpinum research,integrates scattered information,and suggests pathways for subsequent investigation.This study retrieved Chinese literature from the China National Knowledge Infrastructure(CNKI)platform and international literature from the Web of Science(WoS),with data collection finalized by March 2025.CiteSpace 6.3.R1 and VOSviewer 1.6.20 were used to visually analyze publication trends,keyword co-occurrence,and author collaboration networks.The analysis has found that Chinese publications rose markedly after 2003 but declined after 2019,focusing largely on chemical components–such as chlorogenic acid and volatile oils–and pharmacological activities.International output,though smaller,grew steadily,with an emphasis on compositional analysis and antioxidant effects.Keyword clustering revealed that both Chinese and global research expanded from foundational taxonomy to chemical constituents,bioactivity,and environmental adaptation.Core author and institutional analyses identified Liaoning University of Traditional Chinese Medicine and the University of Chinese Academy of Sciences as domestic leaders,while the University of Innsbruck(Austria)played a leading international role.In conclusion,this study offers the first systematic summary of research and publishing trends for Leontopodium alpinum,while also identifying key knowledge gaps.Future studies should prioritize multi-omics approaches to clarify the mechanisms of its bioactive compounds and advance clinical application.Due to its notable efficacy against febrile epidemics and respiratory diseases,expanded research is strongly recommended–particularly in light of rising infectious disease risks where this species could serve an essential role.
文摘Cerebral or intracranial aneurysm is a leading cause of subarachnoid hemorrhage. It was initially treated with open surgical clipping but as rapid development of technology a less invasive endovascular coiling technique of aneurysm revolutionized the treatment. Due to tortuous anatomy of parent artery and complicated morphology and location of aneurysm there is ongoing challenge in the complete obliteration of aneurysms. To aid in the advances of treating aneurysm stent assisted endovascular coiling was introduced to give more scaffold support to parent artery and decrease events of coil protrusion from aneurysms. Many types and generation of stents were developed. One of the most recently introduced stent is low profile visualized intraluminal support (LVIS) stent. Due to its low profile nature it can be used in 0.017-inch inner diameter microcatheter and reach small and complex vessels providing high aneurysmal neck coverage which was not possible through other traditional stent. In addition, its braided design with tantalum strands and radiopaque markers make it more visible during stent placement and post procedure stent evaluation. Despite of many advantages of LVIS stent it is related to high rate of thromboembolic complications and technical complications. Aim of this review paper was to evaluate therapeutic safety, effectiveness and feasibility of LVIS stent in endovascular coil embolization of intracranial aneurysms.
基金financially supported by the National Natural Science Foundation of China (Nos. U1867206, 21906115)State Key Laboratory of Analytical Chemistry for Life Science (No. SKLACLS2014)+1 种基金the China Postdoctoral Science Foundation (No. 2020T130456)the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)。
文摘The development of uranyl ion detection technology has exhibited its significance in public security and environmental fields for the radioactivity and chemical toxicity of uranyl ion.The WHO standard of uranyl ion makes it necessary to develop highly sensitive uranyl rapid warning system in drinking water monitoring.Herein,a visualized rapid warning system for trace uranyl ion is carried out based on electrochemiluminescence(ECL) imaging technology to give an ultra-low limit of detection(LOD) and high selectivity.Amidoxime,a bi-functional group with both uranyl ion capturing and co-reactive functions,is modified on a conjugated polymer backbone with strong ECL signal to be prepared into three-in-one polymer nanoparticles(PNPs) with self-enhanced ECL property.The captured uranyl ion can enhance the ECL signal of PNPs via resonance energy transfer process to give the LOD as 0.5 ng/L,which is much lower than the known luminescent uranyl sensors.Furthermore,ECL imaging technology is introduced into realizing visualized uranyl rapid warning,and can be successfully applied on natural water samples.This study provides a novel strategy for uranyl rapid warning,and shows its potential meaning in public security and environmental fields.
基金the National Natural Science Foundation of China,Nos.51935009 and 51821093National key research and development project of China,No.2022YFB3303303+2 种基金Zhejiang University president special fund financed by Zhejiang province,No.2021XZZX008Zhejiang provincial key research and development project of China,Nos.2023C01060,LZY22E060002 and LZ22E050008The Ng Teng Fong Charitable Foundation in the form of ZJU-SUTD IDEA Grant,No.188170-11102.
文摘This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP of scheme design prototype was first built,where thermal,structural,and multidisciplinary knowledge could be integrated for visualization.To implement visualized computing,the membership function of fuzzy decision-making was optimized using a genetic algorithm.Transient thermodynamic,structural statics,and flow field analyses were conducted,especially for glass fiber composite materials,which have the characteristics of high strength,corrosion resistance,temperature resistance,dimensional stability,and electrical insulation.An electrothermal experiment was performed by measuring the temperature and changes in temperature during RP.Infrared thermographs were obtained using thermal field measurements to determine the temperature distribution.A numerical analysis of a lightweight ribbed ergonomic artifact is presented to illustrate the VCDT.Moreover,manufacturability was verified based on a thermal-solid coupled finite element analysis.The physical experiment and practice proved that the proposed VCDT provided a robust design paradigm for a layered RP between the steady balance of electrothermal regulation and manufacturing efficacy under hybrid uncertainties.
基金Project supported by the National Basic Research Program of China (Grant No. 2009 CB724100)the National Natural Science Foundation of China (Grant No. 11172326)
文摘In a Mach 3.8 wind tunnel, both instantaneous and time-averaged flow structures of different scales around a blunt double-cone with or without supersonic film cooling were visualized via nano-tracer planar laser scattering （NPLS）, which has a high spatiotemporal resolution. Three experimental cases with different injection mass flux rates were carried out. Many typical flow structures were clearly shown, such as shock waves, expansion fans, shear layers, mixing layers, and turbulent boundary layers. The analysis of two NPLS images with an interval of 5 us revealed the temporal evolution characteristics of flow structures. With matched pressures, the laminar length of the mixing layer was longer than that in the case with a larger mass flux rate, but the full covered region was shorter. Structures like K-H （Kelvin-Helmholtz） vortices were clearly seen in both flows. Without injection, the flow was similar to the supersonic flow over a backward- facing step, and the structures were relatively simpler, and there was a longer laminar region. Large scale structures such as hairpin vortices were visualized. In addition, the results were compared in part with the schlieren images captured by others under similar conditions.
文摘To work efficiently with DSS, most users need assistance in representation conversion, i. e., translating the specific outcome from the DSS into the universal language of visual. In generally, it is much easier to understand the results from the DSS if they are translated into charts, maps, and other scientific displays, because visualization exploits human natural ability to recognize and understand visual pattern. In this paper we discuss the concept of visualization for DSS. AniGraftool, a software system, is introduced as an example of Visualized User Interface for DSS.
基金Supported by the National Natural Science Foundation of China (41330319 and 42072174)Foundation of China University of Petroleum Beijing (2462020XKBH016)Fellowship of China Postdoctoral Science Foundation (2020M680030)。
文摘A micro-nano pore three-dimensional visualized real-time physical simulation of natural gas charging, in-situ pore-scale computation, pore network modelling, and apparent permeability evaluation theory were used to investigate laws of gas and water flow and their distribution, and controlling factors during the gas charging process in low-permeability(tight) sandstone reservoir. By describing features of gas-water flow and distribution and their variations in the micro-nano pore system, it is found that the gas charging in the low permeability(tight) sandstone can be divided into two stages, expansion stage and stable stage. In the expansion stage, the gas flows continuously first into large-sized pores then small-sized pores, and first into centers of the pores then edges of pores;pore-throats greater than 20 μm in radius make up the major pathway for gas charging. With the increase of charging pressure, movable water in the edges of large-sized pores and in the centers of small pores is displaced out successively. Pore-throats of 20-50 μm in radius and pore-throats less than 20 μm in radius dominate the expansion of gas charging channels at different stages of charging in turn, leading to reductions in pore-throat radius, throat length and coordination number of the pathway, which is the main increase stage of gas permeability and gas saturation. Among which, pore-throats 30-50 μm in radius control the increase pattern of gas saturation. In the stable stage, gas charging pathways have expanded to the maximum, so the pathways keep stable in pore-throat radius, throat length, and coordination number, and irreducible water remains in the pore system, the gas phase is in concentrated clusters, while the water phase is in the form of dispersed thin film, and the gas saturation and gas permeability tend stable. Connected pore-throats less than 20 μm in radius control the expansion limit of the charging pathways, the formation of stable gas-water distribution, and the maximum gas saturation. The heterogeneity of connected pore-throats affects the dynamic variations of gas phase charging and gas-water distribution. It can be concluded that the pore-throat configuration and heterogeneity of the micro-nanometer pore system control the dynamic variations of the low-permeability(tight) sandstone gas charging process and gas-water distribution features.
基金Supported by the Major State Basic Research Development Program of China(2012CB720500)the National Natural Science Foundation of China(6133301021276078)+3 种基金the National Science Fund for Outstanding Young Scholars(61222303)the Fundamental Research Funds for the Central Universities,Shanghai Rising-Star Program(13QH1401200)the Program for New Century Excellent Talents in University(NCET-10-0885)Shanghai R&D Platform Construction Program(13DZ2295300)
文摘Purified terephthalic acid(PTA) is an important chemical raw material. P-xylene(PX) is transformed to terephthalic acid(TA) through oxidation process and TA is refined to produce PTA. The PX oxidation reaction is a complex process involving three-phase reaction of gas, liquid and solid. To monitor the process and to improve the product quality, as well as to visualize the fault type clearly, a fault diagnosis method based on selforganizing map(SOM) and high dimensional feature extraction method, local tangent space alignment(LTSA),is proposed. In this method, LTSA can reduce the dimension and keep the topology information simultaneously,and SOM distinguishes various states on the output map. Monitoring results of PX oxidation reaction process indicate that the LTSA–SOM can well detect and visualize the fault type.
基金supported by the National Key Research and Development Project(2019YFA0708700)the National Natural Science Foundation of China(52104061)+2 种基金the project funded by China Postdoctoral Science Foundation(2020M682264)the Shandong Provincial Natural Science Foundation(ZR2021QE075)the Fundamental Research Funds for the Central Universities(20CX06090A)。
文摘Knowledge of migration and retention mechanisms of elastic gel particles(EGPs)in pore-throats is essential for the effective application of EGPs as a smart sweep improvement and profile control agent for enhanced oil recovery(EOR).The matching coefficient(defined as the ratio of particle size to pore-throat size)is used to investigate its influence on migration,retention and profile control performance of EGPs.A 1-D continuous pore-throat visualization model(PTVM),a 2-D heterogeneous PTVM and a 3-D heterogeneous core model were constructed and used to investigate pore-scale migration,retention and controlling mechanism of migration and retention characteristics on EGPs profile control.The results of the 1-D continuous PTVM indicated that while the matching coefficient was in the optimal range(i.e.,0.20-0.32),the EGPs could not only smoothly migrate to the deeper pore-throats,but also form stable retention in the pores to resist the erosion of injected water,which was conducive to the effective indepth profile control.The results of the 2-D heterogeneous PTVM verified that the sweep efficiency in low-permeability regions could be significantly improved by in-depth migration and stable retention of EGPs in the pore-throats with an optimal matching coefficient(0.29),which was much better than that in cases with a smaller matching coefficient(0.17)or an excessive matching coefficient(0.39).Moreover,the NMR displacement experiments of 3-D heterogeneous cores were carried out to simulate the EGPs profile control in actual reservoir porous media.Saturation images and T2 spectrum curves of crude oil showed that EOR in the low-permeability layer was highest(56.1%)using EGPs profile control with an optimal matching coefficient,attributing to the in-depth migration and stable retention of EGPs.
文摘With the social development, we are stepping into an information technology world. In such a world, our life is getting more and more diversified and rich because of e-business. E-business not only provides us convenience but also large amounts of business data. However, how shall we better store, manage and use these business data has become a major field being studied by e-business. With the rapid growth of data volume, the relational database system cannot meet the requirements of the current status. In this paper, focusing on the visualized analysis model of Hadoop business data, it analyzed the business data in terms of the visualized platform, database and analysis model etc. Depending on the analysis, offline-data analysis and data visualization for Hive database will be greatly improved, so that references and suggestions can be provided for the visualized analysis model of Hadoop business data.
文摘Objective: This study visualizes and analyzes the current status, hotspots, and frontiers of cardiac rehabilitation for patients with Coronary Heart Disease (CHD) over the past decade (2012.01-2022.12), and explores the future development trend and research direction of the CR for CHD patients in China. Methods: Relevant literature was searched, screened and downloaded from the Web of Science (WOS) database, and bibliometric and visualization analyses were performed using CiteSpace VI software. Results: Through the search and screening of related literature, 2443 English articles were finally included. Among them, most of the Chinese publishers were mainly universities and had less connection with each other, while the foreign publishers were mainly universities and medical institutions in the United States and Europe, and had close connection with each other. The research content of Chinese scholars mainly focuses on the assessment of patients’ life and psychological status, as well as the assessment of cardiac function. Foreign research focuses on physical training assessment, disease perception, etc. Conclusion: Through visualizing relevant research with CiteSpace VI software in the form of a knowledge map, the research frontiers and trends in the field of cardiac rehabilitation for coronary heart disease patients in China and abroad can be discovered more intuitively. Compared with foreign research, the development of cardiac rehabilitation for coronary heart disease patients in China is relatively slow and insufficient, and institutions lack cooperation. In the future, China should accelerate the connection between regions in the field of cardiac rehabilitation and develop a cardiac rehabilitation model suitable for coronary heart disease patients in China with its own characteristics.
文摘The 2020 TKK Science Award in I Life Sciences went to CAS member SHI Yigong,a distinguished structural biologist,for his achievements in:elucidating the yeast and human splicing cycle in atomic detail,which allows us to visually appreciate the dynamic process of the supermolecular machinery of spliceosome performing molecular surgery on the chain of a pre-message RNA(pre-mRNA)to give rise to a mature mRNA.
基金supported by the National Natural Science Foundation of China Joint Fund for Enterprise Innovation and Development,Enrichment Mechanism and Stereoscopic Development of Shale Oil in Continental Rift Basins(No.U24B6002).
文摘Temporary plugging and diversion fracturing(TPDF)is widely used to promote the uniform and complex distribution of multi-clustered hydraulic fractures(HFs)in a horizontal well of the unconventional formations.However,the migration behavior of temporary plugging agent(TPA),as a function of the concentration and particle size of TPA and cluster-perforation numbers,etc.,determining the effectiveness of this technique,remains unclear.Therefore,this study conducted innovatively a series of TPDF simulation experiments on transparent polymethyl methacrylate(PMMA)specimens(cubic block of 30 cm×30 cm×30 cm)to explore visually the migration behavior of TPA in multi-clustered HFs in a horizontal well.A laboratory hydraulic sandblasting perforation completion technique was implemented to simulate the multi-cluster perforations.All the distributions of wellbore,perforations,HFs,and TPA can be seen clearly inside the PMMA specimen post the experiment.The results show that there are four characteristic plugging positions for the TPA:mouth of HF,middle of HF,tip of HF,and the intersection of HFs.Small particle size TPA tends to migrate to the fracture tip for plugging,while large particle size TPA tends to plug at the fracture mouth.The migration of the TPA is influenced obviously by the morphology of the fracture wall.A smooth fracture wall is conducive to the migration of the TPA to the far end of HFs,but not conducive to generating the plugging zone and HF diversion.In contrast,a"leaf vein"fracture of rough wall is conducive to generating the plugging layer and the diversion of HFs,but not conducive to the migration of the TPA to the far end of HFs.The migration ability of TPA in a"shell"pattern is intermediate between the two above cases.Increasing TPA concentration can encourage TPA to migrate more quickly to the characteristic plugging position,and thereby to promote the creation of effective plugging and subsequently the multi-stage diversion of the HFs.Nevertheless,excessive concentration may cause the TPA to settle prematurely,affecting the propagation of the HFs to the far end.Increasing the number of clusters to a certain extent can encourage TPA to migrate into the HFs and form plugging,and promote the diversion.An evaluation system for the migration ability of granular TPA has been established,and it was calculated that when there is no plugging expectation target,the comprehensive migration ability of small particle size TPA is stronger than that of large particle size TPA.This research provides theoretical foundation for the optimization of temporary plugging parameters.
基金Kunming Health Science and Technology Talent Cultivation Project(Project No.:2023-Cultivation Category-00)Health Research Project of Kunming Municipal Health Commission(Project No.:2022-14-04-006)。
文摘Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.
文摘气候变化和人类活动对水文循环产生了显著影响,尤其是在干旱半干旱区.为探究变化环境下典型半干旱生态脆弱区毛乌素沙地水循环演变特征,利用WEP-L(water and energy transfer processes in large river basin)地表水模型和Visual MODFLOW(visual modular finite difference groundwater flow)地下水模型对毛乌素沙地水循环过程进行分布式模拟,基于白家川水文站实测月径流量和监测井地下水位数据进行模型参数率定与验证.结果表明,地表水模型率定期和验证期的模拟月径流量和实测月径流量的R2都在0.5以上,模拟的监测井地下水位和实测地下水位趋势较为一致,相关系数达到0.56以上.采用偏差校正的CMIP6多模式集合气候变化情景及当地取用水情景驱动地表水-地下水耦合模型,量化了变化环境下毛乌素沙地2021-2040年关键水循环要素变化特征.结果表明,未来情景下毛乌素沙地年降水量和年蒸散发量的平均增幅分别为8.0%和7.4%,年径流深呈现逐渐减少的趋势,2040年末地下水位相较于2021年末下降了约1 m.未来2种用水情景下区域地下水总补给量与排泄量的差值分别为-1.82亿、-0.97亿m^(3)·a^(-1),地表径流总量与地表用水量的差值分别为1.83亿、2.29亿m^(3)·a^(-1),地下水资源开发利用将面临更大挑战.研究成果可为毛乌素沙地区域水资源规划与管理提供科学支撑.
