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Novel approach of crater detection by crater candidate region selection and matrix-pattern-oriented least squares support vector machine 被引量:4
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作者 Ding Meng Cao Yunfeng Wu Qingxian 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2013年第2期385-393,共9页
Impacted craters are commonly found on the surface of planets, satellites, asteroids and other solar system bodies. In order to speed up the rate of constructing the database of craters, it is important to develop cra... Impacted craters are commonly found on the surface of planets, satellites, asteroids and other solar system bodies. In order to speed up the rate of constructing the database of craters, it is important to develop crater detection algorithms. This paper presents a novel approach to automatically detect craters on planetary surfaces. The approach contains two parts: crater candidate region selection and crater detection. In the first part, crater candidate region selection is achieved by Kanade-Lucas-Tomasi (KLT) detector. Matrix-pattern-oriented least squares support vector machine (MatLSSVM), as the matrixization version of least square support vector machine (SVM), inherits the advantages of least squares support vector machine (LSSVM), reduces storage space greatly and reserves spatial redundancies within each image matrix compared with general LSSVM. The second part of the approach employs MatLSSVM to design classifier for crater detection. Experimental results on the dataset which comprises 160 preprocessed image patches from Google Mars demonstrate that the accuracy rate of crater detection can be up to 88%. In addition, the outstanding feature of the approach introduced in this paper is that it takes resized crater candidate region as input pattern directly to finish crater detection. The results of the last experiment demonstrate that MatLSSVM-based classifier can detect crater regions effectively on the basis of KLT-based crater candidate region selection. 展开更多
关键词 Crater candidate region Crater detection algorithm Kanade–Lucas–Tomasi detector Least squares support vector machine matrixization
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Performance Prediction Based on Statistics of Sparse Matrix-Vector Multiplication on GPUs 被引量:1
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作者 Ruixing Wang Tongxiang Gu Ming Li 《Journal of Computer and Communications》 2017年第6期65-83,共19页
As one of the most essential and important operations in linear algebra, the performance prediction of sparse matrix-vector multiplication (SpMV) on GPUs has got more and more attention in recent years. In 2012, Guo a... As one of the most essential and important operations in linear algebra, the performance prediction of sparse matrix-vector multiplication (SpMV) on GPUs has got more and more attention in recent years. In 2012, Guo and Wang put forward a new idea to predict the performance of SpMV on GPUs. However, they didn’t consider the matrix structure completely, so the execution time predicted by their model tends to be inaccurate for general sparse matrix. To address this problem, we proposed two new similar models, which take into account the structure of the matrices and make the performance prediction model more accurate. In addition, we predict the execution time of SpMV for CSR-V, CSR-S, ELL and JAD sparse matrix storage formats by the new models on the CUDA platform. Our experimental results show that the accuracy of prediction by our models is 1.69 times better than Guo and Wang’s model on average for most general matrices. 展开更多
关键词 SPARSE matrix-vector MULTIPLICATION Performance Prediction GPU Normal DISTRIBUTION UNIFORM DISTRIBUTION
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以编译为导向的Matrix-DSP程序分析与优化 被引量:2
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作者 荀长庆 陈照云 +2 位作者 文梅 孙海燕 马奕民 《计算机工程与科学》 CSCD 北大核心 2020年第10期1791-1800,共10页
数字信号处理器(DSP)在图像处理、自动化控制、信号处理等多个领域具有广泛应用。自主研发的Matrix DSP采用了典型的单指令多数据SIMD+超长指令字VLIW的向量化架构,因此面向该架构如何实现高效的向量化编程与优化是一项重要挑战。基于Ma... 数字信号处理器(DSP)在图像处理、自动化控制、信号处理等多个领域具有广泛应用。自主研发的Matrix DSP采用了典型的单指令多数据SIMD+超长指令字VLIW的向量化架构,因此面向该架构如何实现高效的向量化编程与优化是一项重要挑战。基于Matrix DSP的体系结构特点,以编译器性能为导向,对内核级代码常用的分析优化手段进行梳理和总结,并结合一个通用矩阵乘的例子进行展示,其执行性能可最高提升1个数量级。最后,从编译器优化和程序员高效编程的角度提出了一些后续的思考与讨论。 展开更多
关键词 matrix DSP 向量化编程 程序优化 编译器
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基于改进i-vector的说话人感知训练方法研究
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作者 梁玉龙 屈丹 邱泽宇 《计算机工程》 CAS CSCD 北大核心 2018年第5期262-267,共6页
基于辨识向量(i-vector)的说话人感知训练方法使用MFCC作为输入特征对i-vector进行提取,但MFCC较差的特征鲁棒性会影响该训练方法的识别性能。为此,提出一种基于改进i-vector的说话人感知训练方法。设计基于SVD的低维特征提取方法,用其... 基于辨识向量(i-vector)的说话人感知训练方法使用MFCC作为输入特征对i-vector进行提取,但MFCC较差的特征鲁棒性会影响该训练方法的识别性能。为此,提出一种基于改进i-vector的说话人感知训练方法。设计基于SVD的低维特征提取方法,用其提取的特征替代MFCC对表征能力更优的i-vector进行提取。实验结果表明,在捷克语语料库中,相对于DNN-HMM语音识别系统与原始基于i-vector的说话人感知训练方法,该方法的识别性能分别提升了1.62%与1.52%,在WSJ语料库中,该方法识别性能分别提升了3.9%和1.48%。 展开更多
关键词 说话人感知训练 辨识向量 深度神经网络 奇异值矩阵分解 瓶颈特征
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New recursive algorithm for matrix inversion 被引量:4
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作者 Cao Jianshu Wang Xuegang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2008年第2期381-384,共4页
To reduce the computational complexity of matrix inversion, which is the majority of processing in many practical applications, two numerically efficient recursive algorithms (called algorithms I and II, respectively... To reduce the computational complexity of matrix inversion, which is the majority of processing in many practical applications, two numerically efficient recursive algorithms (called algorithms I and II, respectively) are presented. Algorithm I is used to calculate the inverse of such a matrix, whose leading principal minors are all nonzero. Algorithm II, whereby, the inverse of an arbitrary nonsingular matrix can be evaluated is derived via improving the algorithm I. The implementation, for algorithm II or I, involves matrix-vector multiplications and vector outer products. These operations are computationally fast and highly parallelizable. MATLAB simulations show that both recursive algorithms are valid. 展开更多
关键词 recursive algorithm matrix inversion matrix-vector product leading principal minor (LPM).
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用说话人相似度i-vector的非负值矩阵分解说话人聚类 被引量:1
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作者 哈尔肯别克.木哈西 钟珞 达瓦.伊德木草 《计算机应用与软件》 2017年第4期165-168,242,共5页
基于贝叶斯或者全贝叶斯准则的说话人自动聚类或者识别方法,主要采取重复换算全发话语音段的相似量度,再组合相似性较大的语音片段实现说话人的聚类。这种方法中如果发话语音片段数越多,组合计算时间就越长,系统实时性变差,而且各说话... 基于贝叶斯或者全贝叶斯准则的说话人自动聚类或者识别方法,主要采取重复换算全发话语音段的相似量度,再组合相似性较大的语音片段实现说话人的聚类。这种方法中如果发话语音片段数越多,组合计算时间就越长,系统实时性变差,而且各说话人模型用GMM方法建立,发话语音时间短暂时GMM的信赖性降低,最终影响说话人聚类精度。针对上述问题,提出引用i-vector说话人相似度的非负值矩阵分解的高精度快速说话人聚类方法。 展开更多
关键词 说话人分割及聚类 非负值矩阵分解 i-vector GMM 电话语音
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Kernel matrix learning with a general regularized risk functional criterion 被引量:3
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作者 Chengqun Wang Jiming Chen +1 位作者 Chonghai Hu Youxian Sun 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2010年第1期72-80,共9页
Kernel-based methods work by embedding the data into a feature space and then searching linear hypothesis among the embedding data points. The performance is mostly affected by which kernel is used. A promising way is... Kernel-based methods work by embedding the data into a feature space and then searching linear hypothesis among the embedding data points. The performance is mostly affected by which kernel is used. A promising way is to learn the kernel from the data automatically. A general regularized risk functional (RRF) criterion for kernel matrix learning is proposed. Compared with the RRF criterion, general RRF criterion takes into account the geometric distributions of the embedding data points. It is proven that the distance between different geometric distdbutions can be estimated by their centroid distance in the reproducing kernel Hilbert space. Using this criterion for kernel matrix learning leads to a convex quadratically constrained quadratic programming (QCQP) problem. For several commonly used loss functions, their mathematical formulations are given. Experiment results on a collection of benchmark data sets demonstrate the effectiveness of the proposed method. 展开更多
关键词 kernel method support vector machine kernel matrix learning HKRS geometric distribution regularized risk functional criterion.
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Classification using wavelet packet decomposition and support vector machine for digital modulations 被引量:4
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作者 Zhao Fucai Hu Yihua Hao Shiqi 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2008年第5期914-918,共5页
To make the modulation classification system more suitable for signals in a wide range of signal to noise rate (SNR), a feature extraction method based on signal wavelet packet transform modulus maxima matrix (WPT... To make the modulation classification system more suitable for signals in a wide range of signal to noise rate (SNR), a feature extraction method based on signal wavelet packet transform modulus maxima matrix (WPTMMM) and a novel support vector machine fuzzy network (SVMFN) classifier is presented. The WPTMMM feature extraction method has less computational complexity, more stability, and has the preferable advantage of robust with the time parallel moving and white noise. Further, the SVMFN uses a new definition of fuzzy density that incorporates accuracy and uncertainty of the classifiers to improve recognition reliability to classify nine digital modulation types (i.e. 2ASK, 2FSK, 2PSK, 4ASK, 4FSK, 4PSK, 16QAM, MSK, and OQPSK). Computer simulation shows that the proposed scheme has the advantages of high accuracy and reliability (success rates are over 98% when SNR is not lower than 0dB), and it adapts to engineering applications. 展开更多
关键词 modulation classification wavelet packet transform modulus maxima matrix support vector machine fuzzy density.
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Stability of GM(1,1) power model on vector transformation 被引量:2
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作者 Jinhai Guo Xinping Xiao +1 位作者 Jun Liu Shuhua Mao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2015年第1期103-109,共7页
The morbidity problem of the GM(1,1) power model in parameter identification is discussed by using multiple and rotation transformation of vectors. Firstly we consider the morbidity problem of the special matrix and... The morbidity problem of the GM(1,1) power model in parameter identification is discussed by using multiple and rotation transformation of vectors. Firstly we consider the morbidity problem of the special matrix and prove that the condition number of the coefficient matrix is determined by the ratio of lengths and the included angle of the column vector, which could be adjusted by multiple and rotation transformation to turn the matrix to a well-conditioned one. Then partition the corresponding matrix of the GM(1,1) power model in accordance with the column vector and regulate the matrix to a well-conditioned one by multiple and rotation transformation of vectors, which completely solve the instability problem of the GM(1,1) power model. Numerical results show that vector transformation is a new method in studying the stability problem of the GM(1,1) power model. 展开更多
关键词 grey power model STABILITY MORBIDITY vector transformation condition number of matrix
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On the completeness of eigen and root vector systems for fourth-order operator matrices and their applications 被引量:1
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作者 王华 阿拉坦仓 黄俊杰 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第10期8-14,共7页
In this paper, we consider the eigenvalue problem of a class of fourth-order operator matrices appearing in mechan- ics, including the geometric multiplicity, algebraic index, and algebraic multiplicity of the eigenva... In this paper, we consider the eigenvalue problem of a class of fourth-order operator matrices appearing in mechan- ics, including the geometric multiplicity, algebraic index, and algebraic multiplicity of the eigenvalue, the symplectic orthogonality, and completeness of eigen and root vector systems. The obtained results are applied to the plate bending problem. 展开更多
关键词 operator matrix eigenvalue problem EIGENvector root vector COMPLETENESS
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畸变Data Matrix码图像的倾斜校正算法研究 被引量:4
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作者 关博熠 董静薇 +1 位作者 马晓峰 徐博 《哈尔滨理工大学学报》 CAS 北大核心 2018年第5期100-105,共6页
针对Data Matrix码倾斜校正中需要多次旋转的问题,本文提出了一种畸变二维码倾斜校正方法。首先使用LoG算子对二值化后的图像进行边缘检测,再基于Data Matrix码的结构特征,通过Hough变换有效快速地确定定位符"L"所在的位置,并... 针对Data Matrix码倾斜校正中需要多次旋转的问题,本文提出了一种畸变二维码倾斜校正方法。首先使用LoG算子对二值化后的图像进行边缘检测,再基于Data Matrix码的结构特征,通过Hough变换有效快速地确定定位符"L"所在的位置,并将"L"型交点用两条向量表示。然后通过向量叉乘计算出Data Matrix码的旋转角度、确定旋转方向,只需一次旋转即可实现倾斜校正。本文算法节省了Data Matrix码在图像恢复过程中所需的时间和工作量。 展开更多
关键词 DATA matrix 倾斜校正 LOG算子 HOUGH变换 向量叉乘
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Using position specific scoring matrix and auto covariance to predict protein subnuclear localization 被引量:2
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作者 Rong-Quan Xiao Yan-Zhi Guo +4 位作者 Yu-Hong Zeng Hai-Feng Tan Hai-Feng Tan Xue-Mei Pu Meng-Long Li 《Journal of Biomedical Science and Engineering》 2009年第1期51-56,共6页
The knowledge of subnuclear localization in eukaryotic cells is indispensable for under-standing the biological function of nucleus, genome regulation and drug discovery. In this study, a new feature representation wa... The knowledge of subnuclear localization in eukaryotic cells is indispensable for under-standing the biological function of nucleus, genome regulation and drug discovery. In this study, a new feature representation was pro-posed by combining position specific scoring matrix (PSSM) and auto covariance (AC). The AC variables describe the neighboring effect between two amino acids, so that they incorpo-rate the sequence-order information;PSSM de-scribes the information of biological evolution of proteins. Based on this new descriptor, a support vector machine (SVM) classifier was built to predict subnuclear localization. To evaluate the power of our predictor, the benchmark dataset that contains 714 proteins localized in nine subnuclear compartments was utilized. The total jackknife cross validation ac-curacy of our method is 76.5%, that is higher than those of the Nuc-PLoc (67.4%), the OET- KNN (55.6%), AAC based SVM (48.9%) and ProtLoc (36.6%). The prediction software used in this article and the details of the SVM parameters are freely available at http://chemlab.scu.edu.cn/ predict_SubNL/index.htm and the dataset used in our study is from Shen and Chou’s work by downloading at http://chou.med.harvard.edu/ bioinf/Nuc-PLoc/Data.htm. 展开更多
关键词 POSITION Specific SCORING matrix AUTO COVARIANCE Support vector Machine Protein SUBNUCLEAR Localization Prediction
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High Performance Control of Matrix Converter Fed Induction Motor Drive System 被引量:1
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作者 孙凯 黄立培 MATSUSE Kouki 《电工电能新技术》 CSCD 北大核心 2007年第2期11-15,共5页
Matrix converter fed motor drive is superior to pulse width modulation inverter drives since it not only provides bi-directional power flow,sinusoidal input/output currents,unity input power factor,but also allows a c... Matrix converter fed motor drive is superior to pulse width modulation inverter drives since it not only provides bi-directional power flow,sinusoidal input/output currents,unity input power factor,but also allows a compact design due to the lack of DC-link capacitors for energy storage.In this paper,model and control of matrix converter fed induction motor drive system are analyzed.A combined control strategy is simplified and improved,which realizes space vector pulse width modulation of matrix converter and rotor flux oriented vector control technique for induction motor drive simultaneously.This control strategy combines the advantages of matrix converter with the good drive performance of vector control technique.Experimental results demonstrate the feasibility and effectiveness of the proposed control strategy. 展开更多
关键词 异步电动机 无线电 电力控制 电池脉冲
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Construction Vectors for Visual Cryptographic Schemes
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作者 FEI Ruchun 《Wuhan University Journal of Natural Sciences》 CAS 2014年第5期441-448,共8页
The concept of group construction vector and independent construction vector for visual cryptography is proposed, and the method based on construction vector is presented for con-structing basis matrices. The general ... The concept of group construction vector and independent construction vector for visual cryptography is proposed, and the method based on construction vector is presented for con-structing basis matrices. The general solutions to construction vectors and the general solutions to k out of n visual cryptographic schemes are obtained. Using the construction vectors, everyone can construct visual cryptographic schemes simply and efficaciously according to the formulas. The concept and the general solutions to construction vector present a good idea for researches on visual cryptographic schemes, including structural properties, the bound of pixel expansion and contrast, and optimal construction. 展开更多
关键词 visual cryptographic scheme basis matrix groupconstruction vector independent construction vector
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An online estimator for rotor resistance in vector drives of induction machines based on Walsh functions
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作者 Hamidreza SHIRAZI Jalal NAZARZADEH 《Control Theory and Technology》 EI CSCD 2014年第4期402-412,共11页
In a modern electrical driver, rotor field oriented control an appropriate transient response. In this method, the space (RFOC) method has been used to achieve a good performance and vector of the rotor flux comes h... In a modern electrical driver, rotor field oriented control an appropriate transient response. In this method, the space (RFOC) method has been used to achieve a good performance and vector of the rotor flux comes handy by the rotor resistance value. The rotor resistance is one of the important parameters which varies according to motor speed and room temperature alteration. In this paper, a new on-line estimation method is utilized to obtain the rotor resistance by using Walsh functions domain. The Walsh functions are one of the most applicable functions in piecewise constant basis functions (PCBF) to solve dynamic equations. On the other hand, an integral operational matrix is used to simplify the process and speed of the computation algorithm. The simulations results show that the proposed method is capable of solving the dynamic equations in an electrical machine on a time interval which robustly estimates the rotor resistance in contrast with injection noises. 展开更多
关键词 vector control Walsh functions Operational matrix Rotor resistance estimation
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Direction and polarization estimation for coherent sources using vector sensors 被引量:3
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作者 Jun Liu Zheng Liu Qin Liu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2013年第4期600-605,共6页
A two-dimensional direction-of-arrival (DOA) and polarization estimation algorithm for coherent sources using a linear vector-sensor array is presented. Two matrices are first constructed by the receiving data. The ... A two-dimensional direction-of-arrival (DOA) and polarization estimation algorithm for coherent sources using a linear vector-sensor array is presented. Two matrices are first constructed by the receiving data. The ranks of the two matrices are only related to the DOAs of the sources and independent of their coherency. Then the source’s elevation is resolved via the matrix pencil (MP) method, and the singular value decomposition (SVD) is used to reduce the noise effect. Finally, the source’s steering vector is estimated, and the analytics solutions of the source’s azimuth and polarization parameter can be directly computed by using a vector cross-product estimator. Moreover, the proposed algorithm can achieve the unambiguous direction estimates, even if the space between adjacent sensors is larger than a half-wavelength. Theoretical and numerical simulations show the effectiveness of the proposed algorithm. 展开更多
关键词 vector sensor coherent source direction-of-arrival (DOA) POLARIZATION matrix pencil (MP).
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基于缓存数据重用的稀疏矩阵向量乘序列优化
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作者 徐传福 邱昊中 车永刚 《计算机研究与发展》 北大核心 2025年第6期1434-1442,共9页
稀疏线性方程组求解等高性能计算应用常常涉及稀疏矩阵向量乘(SpMV)序列Ax,A2x,…,Asx的计算.上述SpMV序列操作又称为稀疏矩阵幂函数(matrix power kernel,MPK).由于MPK执行多次SpMV且稀疏矩阵保持不变,在缓存(cache)中重用稀疏矩阵,可... 稀疏线性方程组求解等高性能计算应用常常涉及稀疏矩阵向量乘(SpMV)序列Ax,A2x,…,Asx的计算.上述SpMV序列操作又称为稀疏矩阵幂函数(matrix power kernel,MPK).由于MPK执行多次SpMV且稀疏矩阵保持不变,在缓存(cache)中重用稀疏矩阵,可避免每次执行SpMV均从主存加载A,从而缓解SpMV访存受限问题,提升MPK性能.但缓存数据重用会导致相邻SpMV操作之间的数据依赖,现有MPK优化多针对单次SpMV调用,或在实现数据重用时引入过多额外开销.提出了缓存感知的MPK(cache-awareMPK,Ca-MPK),基于稀疏矩阵的依赖图,设计了体系结构感知的递归划分方法,将依赖图划分为适合缓存大小的子图/子矩阵,通过构建分割子图解耦数据依赖,根据特定顺序在子矩阵上调度执行SpMV,实现缓存数据重用.测试结果表明,Ca-MPK相对于Intel OneMKL库和最新MPK实现,平均性能提升分别多达约1.57倍和1.40倍. 展开更多
关键词 稀疏矩阵向量乘 矩阵幂函数 缓存数据重用 数据依赖 稀疏线性方程组求解
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An Improved Atmospheric Vector Radiative Transfer Model Incorporating Rough Ocean Boundaries 被引量:3
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作者 Fan Xue-Hua Chen Hong-Bin +1 位作者 Han Zhi-Gang Lin Long-Fu 《Atmospheric and Oceanic Science Letters》 2010年第3期139-144,共6页
The radiative transfer model (RT3), a vector radiative transfer (VRT) scheme in a plane-parallel atmosphere, was bounded by a rough ocean surface in this study. The boundary problem was solved using a Fourier series d... The radiative transfer model (RT3), a vector radiative transfer (VRT) scheme in a plane-parallel atmosphere, was bounded by a rough ocean surface in this study. The boundary problem was solved using a Fourier series decomposition of the radiation field as a function of the azimuth. For the case of a rough ocean surface, the decomposition was obtained by developing both the Fresnel reflection matrix and the probability distribution of the water facet orientation as Fourier series. The effect of shadowing by ocean surface waves was also considered in the boundary condition. The VRT model can compute the intensity and degree of polarization of the light at the top of the atmosphere (TOA), the ocean surface, and any level of the atmosphere in the ocean-atmosphere system. The results obtained by our model are in good agreement with those computed by Ahmad’s model. The simulated results showed that the shadow effects of wave facets on the intensity and the degree of polarization are negligible except at the ocean surface near the grazing angle, possibly because we did not consider the effect of white caps. 展开更多
关键词 vector radiative transfer rough ocean fresnel reflection matrix wave facet distribution function
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The GPBiCG(m, l) Method for Solving General Matrix Equations
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作者 Basem I. Selim Lei DU +1 位作者 Bo YU Xuanru ZHU 《Journal of Mathematical Research with Applications》 CSCD 2019年第4期408-432,共25页
The generalized product bi-conjugate gradient(GPBiCG(m,l))method has been recently proposed as a hybrid variant of the GPBi CG and the Bi CGSTAB methods to solve the linear system Ax=b with non-symmetric coefficient m... The generalized product bi-conjugate gradient(GPBiCG(m,l))method has been recently proposed as a hybrid variant of the GPBi CG and the Bi CGSTAB methods to solve the linear system Ax=b with non-symmetric coefficient matrix,and its attractive convergence behavior has been authenticated in many numerical experiments.By means of the Kronecker product and the vectorization operator,this paper aims to develop the GPBi CG(m,l)method to solve the general matrix equation■ and the general discrete-time periodic matrix equations■ which include the well-known Lyapunov,Stein,and Sylvester matrix equations that arise in a wide variety of applications in engineering,communications and scientific computations.The accuracy and efficiency of the extended GPBi CG(m,l)method assessed against some existing iterative methods are illustrated by several numerical experiments. 展开更多
关键词 GPBiCG(m l) METHOD Krylov SUBSPACE METHOD matrix equations KRONECKER product vectorIZATION OPERATOR
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Using the improved position specific scoring matrix and ensemble learning method to predict drug-binding residues from protein sequences
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作者 Juan Li Yongqing Zhang +5 位作者 Wenli Qin Yanzhi Guo Lezheng Yu Xuemei Pu Menglong Li Jing Sun 《Natural Science》 2012年第5期304-312,共9页
Identification of the drug-binding residues on the surface of proteins is a vital step in drug discovery and it is important for understanding protein function. Most previous researches are based on the structural inf... Identification of the drug-binding residues on the surface of proteins is a vital step in drug discovery and it is important for understanding protein function. Most previous researches are based on the structural information of proteins, but the structures of most proteins are not available. So in this article, a sequence-based method was proposed by combining the support vector machine (SVM)-based ensemble learning and the improved position specific scoring matrix (PSSM). In order to take the local environment information of a drug-binding site into account, an improved PSSM profile scaled by the sliding window and smoothing window was used to improve the prediction result. In addition, a new SVM-based ensemble learning method was developed to deal with the imbalanced data classification problem that commonly exists in the binding site predictions. When performed on the dataset of 985 drug-binding residues, the method achieved a very promising prediction result with the area under the curve (AUC) of 0.9264. Furthermore, an independent dataset of 349 drug- binding residues was used to evaluate the pre- diction model and the prediction accuracy is 84.68%. These results suggest that our method is effective for predicting the drug-binding sites in proteins. The code and all datasets used in this article are freely available at http://cic.scu.edu.cn/bioinformatics/Ensem_DBS.zip. 展开更多
关键词 DRUG-BINDING SITE Prediction Position Specific SCORING matrix ENSEMBLE Learning Support vector Machine
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