This study assessed both motor unit population and firing behavior alterations of the first dorsal interosseous(FDI)muscle in six individuals with stroke,toward better understanding muscle weakness after stroke.Motor ...This study assessed both motor unit population and firing behavior alterations of the first dorsal interosseous(FDI)muscle in six individuals with stroke,toward better understanding muscle weakness after stroke.Motor unit population was estimated using the F wave based motor unit number estimation(MUNE)technique,while motor unit firing behavior was extracted through high-density surface electromyography(EMG)decomposition.Inspection of individual subject data disclosed different patterns of motor unit changes associated with post-stroke weakness.Four subjects concurrently demonstrated loss of functioning motor units and reduced motor unit firing rates in the paretic muscle compared with the contralateral muscle.For the remaining two subjects,one showed remarkable decrease of motor unit number but similar firing rates in the paretic muscle,while on the contrary the other subject demonstrated remarkable decrease in motor unit firing rates but similar motor unit number counts in the paretic muscle,compared with the contralateral muscle.Findings from this study add insights in understanding complexity of post-stroke muscle weakness and help development of appropriate in-terventions in stroke rehabilitation targeting specific motor unit impairment.展开更多
基金NIDILRR RERC under 90REMMO001-01-00Taishan Scholar Project of Shandong Province.
文摘This study assessed both motor unit population and firing behavior alterations of the first dorsal interosseous(FDI)muscle in six individuals with stroke,toward better understanding muscle weakness after stroke.Motor unit population was estimated using the F wave based motor unit number estimation(MUNE)technique,while motor unit firing behavior was extracted through high-density surface electromyography(EMG)decomposition.Inspection of individual subject data disclosed different patterns of motor unit changes associated with post-stroke weakness.Four subjects concurrently demonstrated loss of functioning motor units and reduced motor unit firing rates in the paretic muscle compared with the contralateral muscle.For the remaining two subjects,one showed remarkable decrease of motor unit number but similar firing rates in the paretic muscle,while on the contrary the other subject demonstrated remarkable decrease in motor unit firing rates but similar motor unit number counts in the paretic muscle,compared with the contralateral muscle.Findings from this study add insights in understanding complexity of post-stroke muscle weakness and help development of appropriate in-terventions in stroke rehabilitation targeting specific motor unit impairment.
