Open caissons are widely used in foundation engineering because of their load-bearing efficiency and adaptability in diverse soil conditions.However,accurately predicting their undrained bearing capacity in layered so...Open caissons are widely used in foundation engineering because of their load-bearing efficiency and adaptability in diverse soil conditions.However,accurately predicting their undrained bearing capacity in layered soils remains a complex challenge.This study presents a novel application of five ensemble machine(ML)algorithms-random forest(RF),gradient boosting machine(GBM),extreme gradient boosting(XGBoost),adaptive boosting(AdaBoost),and categorical boosting(CatBoost)-to predict the undrained bearing capacity factor(Nc)of circular open caissons embedded in two-layered clay on the basis of results from finite element limit analysis(FELA).The input dataset consists of 1188 numerical simulations using the Tresca failure criterion,varying in geometrical and soil parameters.The FELA was performed via OptumG2 software with adaptive meshing techniques and verified against existing benchmark studies.The ML models were trained on 70% of the dataset and tested on the remaining 30%.Their performance was evaluated using six statistical metrics:coefficient of determination(R²),mean absolute error(MAE),root mean squared error(RMSE),index of scatter(IOS),RMSE-to-standard deviation ratio(RSR),and variance explained factor(VAF).The results indicate that all the models achieved high accuracy,with R²values exceeding 97.6%and RMSE values below 0.02.Among them,AdaBoost and CatBoost consistently outperformed the other methods across both the training and testing datasets,demonstrating superior generalizability and robustness.The proposed ML framework offers an efficient,accurate,and data-driven alternative to traditional methods for estimating caisson capacity in stratified soils.This approach can aid in reducing computational costs while improving reliability in the early stages of foundation design.展开更多
高压电缆长期过热可能导致绝缘热击穿,进而影响电网的稳定性。然而,当前研究主要集中在传统预测模型上,忽略了温度数据的复杂性和动态特征。为了解决此问题,提出一种基于多尺度Patch与卷积交互的电缆温度预测模型(MSP-CI)。首先,采用通...高压电缆长期过热可能导致绝缘热击穿,进而影响电网的稳定性。然而,当前研究主要集中在传统预测模型上,忽略了温度数据的复杂性和动态特征。为了解决此问题,提出一种基于多尺度Patch与卷积交互的电缆温度预测模型(MSP-CI)。首先,采用通道重组采样方法降低输入维度,并构建多尺度Patch分支结构,以实现复杂时间序列的解耦;其次,结合序列分解与卷积交互策略,分别提取粗粒度Patch的宏观信息与细粒度Patch的微观信息;最后,构建注意力融合模块,以动态平衡宏观与微观信息的权重,并得到最终的预测结果。在真实高压电缆温度数据集上的实验结果表明,MSP-CI相较于TimeMixer、PatchTST(Patch Time Series Transformer)和MSGNet(Multi-Scale interseries Graph Network)等基线模型,在均方误差(MSE)上下降了7.02%~34.87%,在平均绝对误差(MAE)上下降了5.15%~32.04%。可见,MSP-CI能有效提升电缆温度预测的准确率,为电力调度运行提供依据。展开更多
Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,con...Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,conventional MNs employ long needles(≥600μm),leading to pain and skin irritation.Moreover,it is critical to stably apply MNs against complex skin surfaces for uniform nanoscale drug delivery.Herein,a dually amplified transdermal patch(MN@EV/SC)is developed as the stem cell-derived EV delivery platform by hierarchically integrating an octopusinspired suction cup(SC)with short MNs(≤300μm).While leveraging the suction effect to induce nanoscale deformation of the stratum corneum,MN@EV/SC minimizes skin damage and enhances the adhesion of MNs,allowing EV to penetrate deeper into the dermis.When MNs of various lengths are applied to mouse skin,the short MNs can elicit comparable corticosterone release to chemical adhesives,whereas long MNs induce a prompt stress response.MN@EV/SC can achieve a remarkable penetration depth(290μm)for EV,compared to that of MN alone(111μm).Consequently,MN@EV/SC facilitates the revitalization of fibroblasts and enhances collagen synthesis in middle-aged mice.Overall,MN@EV/SC exhibits the potential for skin regeneration by modulating the dermal microenvironment and ensuring patient comfort.展开更多
This study investigates the effects of radiation force due to the rotational pitch motion of a wave energy device,which comprises a coaxial bottom-mounted cylindrical caisson in a two-layer fluid,along with a submerge...This study investigates the effects of radiation force due to the rotational pitch motion of a wave energy device,which comprises a coaxial bottom-mounted cylindrical caisson in a two-layer fluid,along with a submerged cylindrical buoy.The system is modeled as a two-layer fluid with infinite horizontal extent and finite depth.The radiation problem is analyzed in the context of linear water waves.The fluid domain is divided into outer and inner zones,and mathematical solutions for the pitch radiating potential are derived for the corresponding boundary valve problem in these zones using the separation of variables approach.Using the matching eigenfunction expansion method,the unknown coefficients in the analytical expression of the radiation potentials are evaluated.The resulting radiation potential is then used to compute the added mass and damping coefficients.Several numerical results for the added mass and damping coefficients are investigated for numerous parameters,particularly the effects of the cylinder radius,the draft of the submerged cylinder,and the density proportion between the two fluid layers across different frequency ranges.The major findings are presented and discussed.展开更多
Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class at...Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.展开更多
BACKGROUND The early diagnosis rate of pancreatic ductal adenocarcinoma(PDAC)is low and the prognosis is poor.It is important to develop an interpretable noninvasive early diagnostic model in clinical practice.AIM To ...BACKGROUND The early diagnosis rate of pancreatic ductal adenocarcinoma(PDAC)is low and the prognosis is poor.It is important to develop an interpretable noninvasive early diagnostic model in clinical practice.AIM To develop an interpretable noninvasive early diagnostic model for PDAC using plasma extracellular vesicle long RNA(EvlRNA).METHODS The diagnostic model was constructed based on plasma EvlRNA data.During the process of establishing the model,EvlRNA-index was introduced,and four algorithms were adopted to calculate EvlRNA-index.After the model was successfully constructed,performance evaluation was conducted.A series of bioinformatics methods were adopted to explore the potential mechanism of EvlRNA-index as the input feature of the model.And the relationship between key characteristics and PDAC were explored at the single-cell level.RESULTS A novel interpretable machine learning framework was developed based on plasma EvlRNA.In this framework,a two-layer classifier was established.A new concept was proposed:EvlRNA-index.Based on EvlRNA-index,a cancer diagnostic model was established,and a good diagnostic effect was achieved.The accuracy of PDACandCPvsHealth-Probabilistic PCA Index-SVM(PDAC and chronic pancreatitis vs health-probabilistic principal component analysis index-support vector machine)(1-18)was 91.51%,with Mathew’s correlation coefficient 0.7760 and area under the curve 0.9560.In the second layer of the model,the accuracy of PDACvsCP-Probabilistic PCA Index-RF(PDAC vs chronic pancreatitis-probabilistic principal component analysis index-random forest)(2-17)was 93.83%,with Mathew’s correlation coefficient 0.8422 and area under the curve 0.9698.Forty-nine PDAC-related genes were identified,among which 16 were known,inferring that the remaining ones were also PDAC-related genes.CONCLUSION An interpretable two-layer machine learning framework was proposed for early diagnosis and prediction of PDAC based on plasma EvlRNA,providing new insights into the clinical value of EvlRNA.展开更多
In the wake of major natural disasters or human-made disasters,the communication infrastruc-ture within disaster-stricken areas is frequently dam-aged.Unmanned aerial vehicles(UAVs),thanks to their merits such as rapi...In the wake of major natural disasters or human-made disasters,the communication infrastruc-ture within disaster-stricken areas is frequently dam-aged.Unmanned aerial vehicles(UAVs),thanks to their merits such as rapid deployment and high mobil-ity,are commonly regarded as an ideal option for con-structing temporary communication networks.Con-sidering the limited computing capability and battery power of UAVs,this paper proposes a two-layer UAV cooperative computing offloading strategy for emer-gency disaster relief scenarios.The multi-agent twin delayed deep deterministic policy gradient(MATD3)algorithm integrated with prioritized experience replay(PER)is utilized to jointly optimize the scheduling strategies of UAVs,task offloading ratios,and their mobility,aiming to diminish the energy consumption and delay of the system to the minimum.In order to address the aforementioned non-convex optimiza-tion issue,a Markov decision process(MDP)has been established.The results of simulation experiments demonstrate that,compared with the other four base-line algorithms,the algorithm introduced in this paper exhibits better convergence performance,verifying its feasibility and efficacy.展开更多
The alpine grassland vegetation on the Qinghai-Tibet Plateau is composed of plant patches in varied sizes.It remains uncertain whether vegetation recovery following grazing exclusion(GE)in degraded grasslands is drive...The alpine grassland vegetation on the Qinghai-Tibet Plateau is composed of plant patches in varied sizes.It remains uncertain whether vegetation recovery following grazing exclusion(GE)in degraded grasslands is driven by increases in patches number(NP),patch size(PS),or both.We based our predictions on two hypotheses:GE intensifies plant competition,and facilitation prevails near patches while competition prevails in interpatch spaces.We predicted that the NP would remain stable or decrease and PS would increase under GE treatment.To evaluate these predictions,we conducted a study in six lightly degraded alpine grasslands under free grazing(FG)conditions in Bangor County,Xizang Autonomous Region,China,with corresponding GE treatments using transects in 2017 and 2018.Results revealed that four sites in 2017 and five sites in 2018 had reduced NP and increased PS,with probabilities of 0.033(2017)and 0.004(2018),respectively,and a joint probability of 0.0001 under the null hypothesis that GE does not affect NP or PS.The NP reduction was solely due to the decrease in small patch sizes.An increase in PS was common across species,and a predominant tendency for NP reduction was observed among species across the sites.The overall changes in NP and PS were primarily driven by the three most abundant species(contributing more than 60%in both years),rather than by shifts in floristic composition.Our findings highlight that vegetation recovery in Bangor alpine steppes following GE relies solely on the expansion of existing patches rather than the recruitment of new ones in interpatch gaps.We recommend prioritizing growth-promoting measures,such as nutrient or water management,over seed addition when assisting with GE for restoring lightly degraded grasslands.展开更多
In this study,we developed a novel bilayered scaffold consisting of a bottom layer composed of the Decellularized Bovine Pericardium(DP)coated with Polyaniline Nanoparticles(PANINPs)and a top layer made of an electros...In this study,we developed a novel bilayered scaffold consisting of a bottom layer composed of the Decellularized Bovine Pericardium(DP)coated with Polyaniline Nanoparticles(PANINPs)and a top layer made of an electrospun Poly(lactic-co-glycolic acid)/Gelatin(PLGA/Gel)membrane incorporated with Vascular Endothelial Growth Fac-tor(VEGF)and hawthorn extract.Functionally,the DP supplies native Extracellular Matrix(ECM)components and mechanical support,while PANINPs provide conductivity.The electrospun PLGA/Gel layer mimics fibrous ECM.It incorporates bioactives,with VEGF promoting pro-angiogenic stimulation and hawthorn extract enhanc-ing anticoagulant activity,as well as increasing surface hydrophilicity.The tissue adhesive ensures the interfacial integrity between the two layers.Decellularization efficiency was confirmed histologically using 4',6-diamidino-2-phenylindole(DAPI)and Hematoxylin-Eosin(H&E)staining.The DP exhibited a DNA content of 115.9±47.8 ng/mg DNA,compared to 982.88±395.42 ng/mg in Native Pericardium(NP).The PANINPs had an average par-ticle size of 104.94±13.7 nm.The conductivity of PANINPs-coated decellularized pericardium was measured to be 9.093±8.6×10-4 S/cm using the four-point probe method.PLGA/Gel membranes containing hawthorn extract(1%,5%,10%,and 15%w/v)and VEGF(0.1μg/mL,0.5μg/mL,and 1μg/mL)were fabricated by electrospinning,result-ing in fiber diameters between 850 and 1200 nm and pore sizes between 14 and 20μm.The anticoagulant efficiency of the membranes containing hawthorn extract reached 430 s in the Activated Partial Thromboplastin Time Assay(aPTT).Mechanical testing revealed a tensile strength of 22.70±6.33 MPa,an elongation of 53.58±10.63%,and Young's modulus of 0.67±0.10 MPa.The scaffold also exhibited over 91%cell viability and excellent cardiomyo-cyte adhesion.The hemolysis ratio was determined to be 0.421±0.191%,which confirms its blood compatibility.Our results indicate that the proposed bilayered scaffold can be a promising candidate for cardiac patch applications.展开更多
In the version of the article originally published in the volume 68,issue 12,2025 of Sci China Mater(pages 4413-4422,https://doi.org/10.1007/s40843-025-3667-7),the Chinese name of the co-first author(肖天孝)was incorr...In the version of the article originally published in the volume 68,issue 12,2025 of Sci China Mater(pages 4413-4422,https://doi.org/10.1007/s40843-025-3667-7),the Chinese name of the co-first author(肖天孝)was incorrect.The corrected Chinese name is:肖天笑.展开更多
Based on the synchronous joint gravity and magnetic inversion of single interface by Pilkington and the need of revealing Cenozoic and crystalline basement thickness in the new round of oil-gas exploration, we propose...Based on the synchronous joint gravity and magnetic inversion of single interface by Pilkington and the need of revealing Cenozoic and crystalline basement thickness in the new round of oil-gas exploration, we propose a joint gravity and magnetic inversion methodfor two-layer models by concentrating on the relationship between the change of thicknessI and position of the middle layer and anomaly and discuss the effects of the key parameters. Model tests and application to field data show the validity of this method.展开更多
A model is proposed to evaluate the,effective modufi of a composite reinforced by two-layered spherical inclusions.This model is based on the localisation problem of a two- layered spherical inclusion embedded in an i...A model is proposed to evaluate the,effective modufi of a composite reinforced by two-layered spherical inclusions.This model is based on the localisation problem of a two- layered spherical inclusion embedded in an infinite matrix.The interations of the reinforced phases are taken into account by using the average matrix stress concept.When the external layer vanishes,the proposed model reduces to the classical Mori-Tanaka's model for spherical inclusions.Theoretical results for the composite of polyester matrix filled by hollow glass spheres and voids show excellent agreement with experimental results.展开更多
Many rock avalanches were triggered by the Wenchuan earthquake on May 12, 2008 in southwest China. Protection galleries covered with a single soil layer are usually used to protect against rockfall. Since one-layer pr...Many rock avalanches were triggered by the Wenchuan earthquake on May 12, 2008 in southwest China. Protection galleries covered with a single soil layer are usually used to protect against rockfall. Since one-layer protection galleries do not have sufficient buffer capacity, a two-layered absorbing system has been designed. This study aims to find whether an expanded poly-styrol （EPS） cushion, which is used in the soil-covered protection galleries for shock absorption, could be positioned under dynamic loadings. The dynamic impacts of the two-layered absorbing system under the conditions of rock avalanches are numerically simulated through a 2D discrete dement method. By selecting reasonable parameters, a series of numerical experiments were conducted to find the best combination for the two- layered absorbing system. The values of the EPS layer area as a percentage of the total area were set as 0% （Sl）, 22~ （S2）, and 70% （$3）. 22~ of the area of the EPS layer was found to be a reasonable value, and experiments were conducted to find the best position of the EPS layer in the two-layered absorbing system. The numerical results yield useful conclusions regarding the interaction between the impacting avalanches and the two-layered absorbing system. The soil layer can absorb the shock energy effectively and S2 （0.4-m thick EPS cushion covered with soil layer） is the most efficient combination, which can reduce the impact force, compared with the other combinations.展开更多
This paper addresses a target-enclosing problem for multiple spacecraft systems by proposing a two-layer affine formation control strategy. Compared with the existing methods,the adopted two-layer network structure in...This paper addresses a target-enclosing problem for multiple spacecraft systems by proposing a two-layer affine formation control strategy. Compared with the existing methods,the adopted two-layer network structure in this paper is generally directed, which is suitable for practical space missions. Firstly, distributed finite-time sliding-mode estimators and formation controllers in both layers are designed separately to improve the flexibility of the formation control system. By introducing the properties of affine transformation into formation control protocol design,the controllers can be used to track different time-varying target formation patterns. Besides, multilayer time-varying encirclements can be achieved with particular shapes to surround the moving target. In the sequel, by integrating adaptive neural networks and specialized artificial potential functions into backstepping controllers, the problems of uncertain Euler-Lagrange models, collision avoidance as well as formation reconfiguration are solved simultaneously. The stability of the proposed controllers is verified by the Lyapunov direct method. Finally, two simulation examples of triangle formation and more complex hexagon formation are presented to illustrate the feasibility of the theoretical results.展开更多
Based on the AfKdV equation of Xu et al.([1]), a theory on the velocities of the precursor soliton generation in two-layer flow over topography is presented in the present paper. Moving velocities of precursor soliton...Based on the AfKdV equation of Xu et al.([1]), a theory on the velocities of the precursor soliton generation in two-layer flow over topography is presented in the present paper. Moving velocities of precursor solitons, of the first zero-crossing of the tailing wavetrain and of the flow behind the topography are found theoretically. It is shown that for a given topography, when its moving velocities are at the resonant points, we have the following rules: the ratio of the moving velocity of the precursor solitons to that of the first zero-crossing of the tailing wavetrain equals -4/3. At the same time, the ratio of the width of generating region of the precursor solitons to that of the depressed water region equals also -4/3. The theoretical results are examined by means of numerical calculation. The comparison between the theoretical and numerical results are found in good agreement. For different stratified parameters of two-layer how, the velocities of the precursor soliton generation are also predicted in terms of the present theoretical results.展开更多
The penetration depth of torpedo anchor in two-layered soil bed was experimentally investigated. A total of 177 experimental data were obtained in laboratory by varying the undrained shear strength of the two-layered ...The penetration depth of torpedo anchor in two-layered soil bed was experimentally investigated. A total of 177 experimental data were obtained in laboratory by varying the undrained shear strength of the two-layered soil and the thickness of the top soil layer. The geometric parameters of the anchor and the soil properties(the liquid limit, plastic limit, specific gravity, undrained shear strength, density, and water content) were measured. Based on the energy analysis and present test data, an empirical formula to predict the penetration depth of torpedo anchor in two-layered soil bed was proposed. The proposed formula was extensively validated by laboratory and field data of previous researchers. The results were in good agreement with those obtained for two-layered and single-layered soil bed.Finally, a sensitivity analysis on the parameters in the formula was performed.展开更多
A weak nonlinear model of a two-layer barotropic ocean with Rayleigh dissipation is built.The analytic asymptotic solution is derived in the mid-latitude stationary wind field,and the physical meaning of the correspon...A weak nonlinear model of a two-layer barotropic ocean with Rayleigh dissipation is built.The analytic asymptotic solution is derived in the mid-latitude stationary wind field,and the physical meaning of the corresponding problem is discussed.展开更多
The hydroelastic response of a circular, very large floating structure(VLFS), idealized as a floating circular elastic thin plate, is investigated for the case of time-harmonic incident waves of the surface and interf...The hydroelastic response of a circular, very large floating structure(VLFS), idealized as a floating circular elastic thin plate, is investigated for the case of time-harmonic incident waves of the surface and interfacial wave modes, of a given wave frequency, on a two-layer fluid of finite and constant depth. In linear potential-flow theory, with the aid of angular eigenfunction expansions, the diffraction potentials can be expressed by the Bessel functions. A system of simultaneous equations is derived by matching the velocity and the pressure between the open-water and the platecovered regions, while incorporating the edge conditions of the plate. Then the complex nested series are simplified by utilizing the orthogonality of the vertical eigenfunctions in the open-water region. Numerical computations are presented to investigate the effects of different physical quantities, such as the thickness of the plate, Young’s modulus, the ratios of the densities and of the layer depths, on the dispersion relations of the flexural-gravity waves for the two-layer fluid. Rapid convergence of the method is observed, but is slower at higher wave frequency. At high frequency, it is found that there is some energy transferred from the interfacial mode to the surface mode.展开更多
This paper tackles the formation-containment control problem of fixed-wing unmanned aerial vehicle(UAV)swarm with model uncertainties for dynamic target tracking in three-dimensional space in the faulty case of UAVs’...This paper tackles the formation-containment control problem of fixed-wing unmanned aerial vehicle(UAV)swarm with model uncertainties for dynamic target tracking in three-dimensional space in the faulty case of UAVs’actuator and sensor.The fixed-wing UAV swarm under consideration is organized as a“multi-leader-multi-follower”structure,in which only several leaders can obtain the dynamic target information while others only receive the neighbors’information through the communication network.To simultaneously realize the formation,containment,and dynamic target tracking,a two-layer control framework is adopted to decouple the problem into two subproblems:reference trajectory generation and trajectory tracking.In the upper layer,a distributed finite-time estimator(DFTE)is proposed to generate each UAV’s reference trajectory in accordance with the control objective.Subsequently,a distributed composite robust fault-tolerant trajectory tracking controller is developed in the lower layer,where a novel adaptive extended super-twisting(AESTW)algorithm with a finite-time extended state observer(FTESO)is involved in solving the robust trajectory tracking control problem under model uncertainties,actuator,and sensor faults.The proposed controller simultaneously guarantees rapidness and enhances the system’s robustness with fewer chattering effects.Finally,corresponding simulations are carried out to demonstrate the effectiveness and competitiveness of the proposed two-layer fault-tolerant cooperative control scheme.展开更多
Tanlu fault zone(TLFZ)is the largest active fault zone in eastern China.It is characterized by complex tectonic evolution and multiple faults and marks the boundary between the North and South China blocks.An indepth ...Tanlu fault zone(TLFZ)is the largest active fault zone in eastern China.It is characterized by complex tectonic evolution and multiple faults and marks the boundary between the North and South China blocks.An indepth understanding of the distinct crustal structures of both parts of the TLFZ will provide valuable insights into the lithospheric and crustal thinning in eastern China,extensive magmatism since the Mesozoic,and formation mechanisms of metallogenic belts along the Yangtze River.In this study,a two-layer H-κstacking approach was adopted to estimate the thicknesses of the sediment and crystalline crust as well as the corresponding vP/vS ratios based on high-quality teleseismic P-wave receiver functions recorded by permanent and temporary stations in and around the TLFZ.The geological units in the study region were delineated,especially the crustal structures beneath extensive sedimentary basins on both sides of the TLFZ.The following conclusions can be drawn:(1)The crustal thickness in and around the TLFZ greatly varies depending on the segment.In the northern segment,the crust is relatively thin beneath the eastern part of the Songliao Basin,a broad uplift of the Moho can be observed,and the Moho descends from south to north.The crust below the central and southern segments becomes thinner from west to east.The thickness of the crust is less than 30 km toward the eastern side of the boundary between the Jiangsu and Anhui provinces,that is,significantly thinner than in other areas.In terms of the vP/vS ratios,high anomalies were detected in the central-southern segments of the TLFZ,indicating the upwelling of deep mantle magma via deep faults.(2)Positive isostatic gravity anomalies were observed in the eastern part of the northern segment of the TLFZ and in the eastern part of the Suwan segment.The crustal thickness is smaller than that obtained from the Airy model of isostasy.This suggests that the lower crust in this area may have experienced intensive transformation processes,which may be related to crustal thinning(caused by crustal extension)and the strong uplift of the mantle in eastern China.The isostatic gravity anomalies between the eastern and western parts of the TLFZ indicate that the fault zone plays a dominant role in controlling the development of the deep crustal structure.(3)Significant crustal thinning was observed beneath the eastern part of the boundary between the Jiangsu and Anhui provinces in the southern segment of the TLFZ,suggesting that this area is prone to lithospheric thinning of the North China Craton.Due to the subduction,compression,and retreat of the Paleo-Pacific Plate during the Yanshanian Period as well as the dehydration of subducting oceanic crust(within subduction zones),the asthenosphere and oceanic crust in eastern China partially melted,resulting in mantle enrichment.The basic magma from the mantle is accumulated at the base of the crust,leading to magmatic underplating.In areas with weak topography toward the east of the TLFZ,magma rises to the upper crust and surface,resulting in the enrichment of multiple metal deposits in this area.展开更多
文摘Open caissons are widely used in foundation engineering because of their load-bearing efficiency and adaptability in diverse soil conditions.However,accurately predicting their undrained bearing capacity in layered soils remains a complex challenge.This study presents a novel application of five ensemble machine(ML)algorithms-random forest(RF),gradient boosting machine(GBM),extreme gradient boosting(XGBoost),adaptive boosting(AdaBoost),and categorical boosting(CatBoost)-to predict the undrained bearing capacity factor(Nc)of circular open caissons embedded in two-layered clay on the basis of results from finite element limit analysis(FELA).The input dataset consists of 1188 numerical simulations using the Tresca failure criterion,varying in geometrical and soil parameters.The FELA was performed via OptumG2 software with adaptive meshing techniques and verified against existing benchmark studies.The ML models were trained on 70% of the dataset and tested on the remaining 30%.Their performance was evaluated using six statistical metrics:coefficient of determination(R²),mean absolute error(MAE),root mean squared error(RMSE),index of scatter(IOS),RMSE-to-standard deviation ratio(RSR),and variance explained factor(VAF).The results indicate that all the models achieved high accuracy,with R²values exceeding 97.6%and RMSE values below 0.02.Among them,AdaBoost and CatBoost consistently outperformed the other methods across both the training and testing datasets,demonstrating superior generalizability and robustness.The proposed ML framework offers an efficient,accurate,and data-driven alternative to traditional methods for estimating caisson capacity in stratified soils.This approach can aid in reducing computational costs while improving reliability in the early stages of foundation design.
文摘高压电缆长期过热可能导致绝缘热击穿,进而影响电网的稳定性。然而,当前研究主要集中在传统预测模型上,忽略了温度数据的复杂性和动态特征。为了解决此问题,提出一种基于多尺度Patch与卷积交互的电缆温度预测模型(MSP-CI)。首先,采用通道重组采样方法降低输入维度,并构建多尺度Patch分支结构,以实现复杂时间序列的解耦;其次,结合序列分解与卷积交互策略,分别提取粗粒度Patch的宏观信息与细粒度Patch的微观信息;最后,构建注意力融合模块,以动态平衡宏观与微观信息的权重,并得到最终的预测结果。在真实高压电缆温度数据集上的实验结果表明,MSP-CI相较于TimeMixer、PatchTST(Patch Time Series Transformer)和MSGNet(Multi-Scale interseries Graph Network)等基线模型,在均方误差(MSE)上下降了7.02%~34.87%,在平均绝对误差(MAE)上下降了5.15%~32.04%。可见,MSP-CI能有效提升电缆温度预测的准确率,为电力调度运行提供依据。
基金supported by National Research Foundation of Korea(NRF)grants funded by the Korean government(MSIT)(No.RS-2023-00256265,RS-2024-00352352,RS-2024-00405818)the Korean Fund for Regenerative Medicine(KFRM)grant funded by the Korea government(the Ministry of Science and ICT,the Ministry of Health&Welfare).(No.25A0102L1)support from the Market-led K-sensor technology program(RS-2022-00154781,Development of large-area wafer-level flexible/stretchable hybrid sensor platform technology for form factor-free highly integrated convergence sensor),funded By the Ministry of Trade,Industry&Energy(MOTIE,Korea).
文摘Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,conventional MNs employ long needles(≥600μm),leading to pain and skin irritation.Moreover,it is critical to stably apply MNs against complex skin surfaces for uniform nanoscale drug delivery.Herein,a dually amplified transdermal patch(MN@EV/SC)is developed as the stem cell-derived EV delivery platform by hierarchically integrating an octopusinspired suction cup(SC)with short MNs(≤300μm).While leveraging the suction effect to induce nanoscale deformation of the stratum corneum,MN@EV/SC minimizes skin damage and enhances the adhesion of MNs,allowing EV to penetrate deeper into the dermis.When MNs of various lengths are applied to mouse skin,the short MNs can elicit comparable corticosterone release to chemical adhesives,whereas long MNs induce a prompt stress response.MN@EV/SC can achieve a remarkable penetration depth(290μm)for EV,compared to that of MN alone(111μm).Consequently,MN@EV/SC facilitates the revitalization of fibroblasts and enhances collagen synthesis in middle-aged mice.Overall,MN@EV/SC exhibits the potential for skin regeneration by modulating the dermal microenvironment and ensuring patient comfort.
基金supported by MHRD as researcher C.K.Neog received the MHRD Institute GATE scholarship from Govt.of India.
文摘This study investigates the effects of radiation force due to the rotational pitch motion of a wave energy device,which comprises a coaxial bottom-mounted cylindrical caisson in a two-layer fluid,along with a submerged cylindrical buoy.The system is modeled as a two-layer fluid with infinite horizontal extent and finite depth.The radiation problem is analyzed in the context of linear water waves.The fluid domain is divided into outer and inner zones,and mathematical solutions for the pitch radiating potential are derived for the corresponding boundary valve problem in these zones using the separation of variables approach.Using the matching eigenfunction expansion method,the unknown coefficients in the analytical expression of the radiation potentials are evaluated.The resulting radiation potential is then used to compute the added mass and damping coefficients.Several numerical results for the added mass and damping coefficients are investigated for numerous parameters,particularly the effects of the cylinder radius,the draft of the submerged cylinder,and the density proportion between the two fluid layers across different frequency ranges.The major findings are presented and discussed.
基金supported by the Institute of Information&Communications Technology Planning&Evaluation(IITP)—Innovative Human Resource Development for Local Intellectualization program grant funded by the Korea government(MSIT)(IITP-2025-RS-2022-00156334)in part by Liaoning Province Nature Fund Project(2024-BSLH-214).
文摘Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.
基金Supported by Talent Scientific Research Start-up Foundation of Wannan Medical College,No.WYRCQD2023045.
文摘BACKGROUND The early diagnosis rate of pancreatic ductal adenocarcinoma(PDAC)is low and the prognosis is poor.It is important to develop an interpretable noninvasive early diagnostic model in clinical practice.AIM To develop an interpretable noninvasive early diagnostic model for PDAC using plasma extracellular vesicle long RNA(EvlRNA).METHODS The diagnostic model was constructed based on plasma EvlRNA data.During the process of establishing the model,EvlRNA-index was introduced,and four algorithms were adopted to calculate EvlRNA-index.After the model was successfully constructed,performance evaluation was conducted.A series of bioinformatics methods were adopted to explore the potential mechanism of EvlRNA-index as the input feature of the model.And the relationship between key characteristics and PDAC were explored at the single-cell level.RESULTS A novel interpretable machine learning framework was developed based on plasma EvlRNA.In this framework,a two-layer classifier was established.A new concept was proposed:EvlRNA-index.Based on EvlRNA-index,a cancer diagnostic model was established,and a good diagnostic effect was achieved.The accuracy of PDACandCPvsHealth-Probabilistic PCA Index-SVM(PDAC and chronic pancreatitis vs health-probabilistic principal component analysis index-support vector machine)(1-18)was 91.51%,with Mathew’s correlation coefficient 0.7760 and area under the curve 0.9560.In the second layer of the model,the accuracy of PDACvsCP-Probabilistic PCA Index-RF(PDAC vs chronic pancreatitis-probabilistic principal component analysis index-random forest)(2-17)was 93.83%,with Mathew’s correlation coefficient 0.8422 and area under the curve 0.9698.Forty-nine PDAC-related genes were identified,among which 16 were known,inferring that the remaining ones were also PDAC-related genes.CONCLUSION An interpretable two-layer machine learning framework was proposed for early diagnosis and prediction of PDAC based on plasma EvlRNA,providing new insights into the clinical value of EvlRNA.
基金supported by the Basic Scientific Research Business Fund Project of Higher Education Institutions in Heilongjiang Province(145409601)the First Batch of Experimental Teaching and Teaching Laboratory Construction Research Projects in Heilongjiang Province(SJGZ20240038).
文摘In the wake of major natural disasters or human-made disasters,the communication infrastruc-ture within disaster-stricken areas is frequently dam-aged.Unmanned aerial vehicles(UAVs),thanks to their merits such as rapid deployment and high mobil-ity,are commonly regarded as an ideal option for con-structing temporary communication networks.Con-sidering the limited computing capability and battery power of UAVs,this paper proposes a two-layer UAV cooperative computing offloading strategy for emer-gency disaster relief scenarios.The multi-agent twin delayed deep deterministic policy gradient(MATD3)algorithm integrated with prioritized experience replay(PER)is utilized to jointly optimize the scheduling strategies of UAVs,task offloading ratios,and their mobility,aiming to diminish the energy consumption and delay of the system to the minimum.In order to address the aforementioned non-convex optimiza-tion issue,a Markov decision process(MDP)has been established.The results of simulation experiments demonstrate that,compared with the other four base-line algorithms,the algorithm introduced in this paper exhibits better convergence performance,verifying its feasibility and efficacy.
基金financially supported by the Science and Technology Bureau of Ali Prefecture,project named“Assessing the Carbon Sequestration and Carbon Sink Enhancement Potential of Natural Ecosystems in Ali Region(QYXTZX-AL2022-05)”。
文摘The alpine grassland vegetation on the Qinghai-Tibet Plateau is composed of plant patches in varied sizes.It remains uncertain whether vegetation recovery following grazing exclusion(GE)in degraded grasslands is driven by increases in patches number(NP),patch size(PS),or both.We based our predictions on two hypotheses:GE intensifies plant competition,and facilitation prevails near patches while competition prevails in interpatch spaces.We predicted that the NP would remain stable or decrease and PS would increase under GE treatment.To evaluate these predictions,we conducted a study in six lightly degraded alpine grasslands under free grazing(FG)conditions in Bangor County,Xizang Autonomous Region,China,with corresponding GE treatments using transects in 2017 and 2018.Results revealed that four sites in 2017 and five sites in 2018 had reduced NP and increased PS,with probabilities of 0.033(2017)and 0.004(2018),respectively,and a joint probability of 0.0001 under the null hypothesis that GE does not affect NP or PS.The NP reduction was solely due to the decrease in small patch sizes.An increase in PS was common across species,and a predominant tendency for NP reduction was observed among species across the sites.The overall changes in NP and PS were primarily driven by the three most abundant species(contributing more than 60%in both years),rather than by shifts in floristic composition.Our findings highlight that vegetation recovery in Bangor alpine steppes following GE relies solely on the expansion of existing patches rather than the recruitment of new ones in interpatch gaps.We recommend prioritizing growth-promoting measures,such as nutrient or water management,over seed addition when assisting with GE for restoring lightly degraded grasslands.
文摘In this study,we developed a novel bilayered scaffold consisting of a bottom layer composed of the Decellularized Bovine Pericardium(DP)coated with Polyaniline Nanoparticles(PANINPs)and a top layer made of an electrospun Poly(lactic-co-glycolic acid)/Gelatin(PLGA/Gel)membrane incorporated with Vascular Endothelial Growth Fac-tor(VEGF)and hawthorn extract.Functionally,the DP supplies native Extracellular Matrix(ECM)components and mechanical support,while PANINPs provide conductivity.The electrospun PLGA/Gel layer mimics fibrous ECM.It incorporates bioactives,with VEGF promoting pro-angiogenic stimulation and hawthorn extract enhanc-ing anticoagulant activity,as well as increasing surface hydrophilicity.The tissue adhesive ensures the interfacial integrity between the two layers.Decellularization efficiency was confirmed histologically using 4',6-diamidino-2-phenylindole(DAPI)and Hematoxylin-Eosin(H&E)staining.The DP exhibited a DNA content of 115.9±47.8 ng/mg DNA,compared to 982.88±395.42 ng/mg in Native Pericardium(NP).The PANINPs had an average par-ticle size of 104.94±13.7 nm.The conductivity of PANINPs-coated decellularized pericardium was measured to be 9.093±8.6×10-4 S/cm using the four-point probe method.PLGA/Gel membranes containing hawthorn extract(1%,5%,10%,and 15%w/v)and VEGF(0.1μg/mL,0.5μg/mL,and 1μg/mL)were fabricated by electrospinning,result-ing in fiber diameters between 850 and 1200 nm and pore sizes between 14 and 20μm.The anticoagulant efficiency of the membranes containing hawthorn extract reached 430 s in the Activated Partial Thromboplastin Time Assay(aPTT).Mechanical testing revealed a tensile strength of 22.70±6.33 MPa,an elongation of 53.58±10.63%,and Young's modulus of 0.67±0.10 MPa.The scaffold also exhibited over 91%cell viability and excellent cardiomyo-cyte adhesion.The hemolysis ratio was determined to be 0.421±0.191%,which confirms its blood compatibility.Our results indicate that the proposed bilayered scaffold can be a promising candidate for cardiac patch applications.
文摘In the version of the article originally published in the volume 68,issue 12,2025 of Sci China Mater(pages 4413-4422,https://doi.org/10.1007/s40843-025-3667-7),the Chinese name of the co-first author(肖天孝)was incorrect.The corrected Chinese name is:肖天笑.
基金Supported by the National Natural Science Foundation of China(Grant No.40674063)National Hi-tech Research and Development Program of China(863Program)(Grant No.2006AA09Z311)
文摘Based on the synchronous joint gravity and magnetic inversion of single interface by Pilkington and the need of revealing Cenozoic and crystalline basement thickness in the new round of oil-gas exploration, we propose a joint gravity and magnetic inversion methodfor two-layer models by concentrating on the relationship between the change of thicknessI and position of the middle layer and anomaly and discuss the effects of the key parameters. Model tests and application to field data show the validity of this method.
文摘A model is proposed to evaluate the,effective modufi of a composite reinforced by two-layered spherical inclusions.This model is based on the localisation problem of a two- layered spherical inclusion embedded in an infinite matrix.The interations of the reinforced phases are taken into account by using the average matrix stress concept.When the external layer vanishes,the proposed model reduces to the classical Mori-Tanaka's model for spherical inclusions.Theoretical results for the composite of polyester matrix filled by hollow glass spheres and voids show excellent agreement with experimental results.
基金financial support from the Project of National Science Foundation of China(Grant No.41272346)the National Outstanding Youth Funds(Grant No.41225011)+2 种基金financial support from the Science & Technology Research Plan of China Railway Eryuan Engineering Group CO.LTD (Grant No.13164196(13-15))the Project of National Science Foundation of China(Grant Nos. 41472293,91430105)"hundred talents" program of CAS
文摘Many rock avalanches were triggered by the Wenchuan earthquake on May 12, 2008 in southwest China. Protection galleries covered with a single soil layer are usually used to protect against rockfall. Since one-layer protection galleries do not have sufficient buffer capacity, a two-layered absorbing system has been designed. This study aims to find whether an expanded poly-styrol （EPS） cushion, which is used in the soil-covered protection galleries for shock absorption, could be positioned under dynamic loadings. The dynamic impacts of the two-layered absorbing system under the conditions of rock avalanches are numerically simulated through a 2D discrete dement method. By selecting reasonable parameters, a series of numerical experiments were conducted to find the best combination for the two- layered absorbing system. The values of the EPS layer area as a percentage of the total area were set as 0% （Sl）, 22~ （S2）, and 70% （$3）. 22~ of the area of the EPS layer was found to be a reasonable value, and experiments were conducted to find the best position of the EPS layer in the two-layered absorbing system. The numerical results yield useful conclusions regarding the interaction between the impacting avalanches and the two-layered absorbing system. The soil layer can absorb the shock energy effectively and S2 （0.4-m thick EPS cushion covered with soil layer） is the most efficient combination, which can reduce the impact force, compared with the other combinations.
基金sponsored by National Natural Science Foundation of China (Nos. 61673327, 51606161, 11602209, 91441128)Natural Science Foundation of Fujian Province of China (No. 2016J06011)China Scholarship Council (No. 201606310153)
文摘This paper addresses a target-enclosing problem for multiple spacecraft systems by proposing a two-layer affine formation control strategy. Compared with the existing methods,the adopted two-layer network structure in this paper is generally directed, which is suitable for practical space missions. Firstly, distributed finite-time sliding-mode estimators and formation controllers in both layers are designed separately to improve the flexibility of the formation control system. By introducing the properties of affine transformation into formation control protocol design,the controllers can be used to track different time-varying target formation patterns. Besides, multilayer time-varying encirclements can be achieved with particular shapes to surround the moving target. In the sequel, by integrating adaptive neural networks and specialized artificial potential functions into backstepping controllers, the problems of uncertain Euler-Lagrange models, collision avoidance as well as formation reconfiguration are solved simultaneously. The stability of the proposed controllers is verified by the Lyapunov direct method. Finally, two simulation examples of triangle formation and more complex hexagon formation are presented to illustrate the feasibility of the theoretical results.
基金The project supported by the National Natural Science Foundation of China under the Grant No.49776284
文摘Based on the AfKdV equation of Xu et al.([1]), a theory on the velocities of the precursor soliton generation in two-layer flow over topography is presented in the present paper. Moving velocities of precursor solitons, of the first zero-crossing of the tailing wavetrain and of the flow behind the topography are found theoretically. It is shown that for a given topography, when its moving velocities are at the resonant points, we have the following rules: the ratio of the moving velocity of the precursor solitons to that of the first zero-crossing of the tailing wavetrain equals -4/3. At the same time, the ratio of the width of generating region of the precursor solitons to that of the depressed water region equals also -4/3. The theoretical results are examined by means of numerical calculation. The comparison between the theoretical and numerical results are found in good agreement. For different stratified parameters of two-layer how, the velocities of the precursor soliton generation are also predicted in terms of the present theoretical results.
基金financially supported by the Ministry of Education of China(Grant No.6141A02022337)
文摘The penetration depth of torpedo anchor in two-layered soil bed was experimentally investigated. A total of 177 experimental data were obtained in laboratory by varying the undrained shear strength of the two-layered soil and the thickness of the top soil layer. The geometric parameters of the anchor and the soil properties(the liquid limit, plastic limit, specific gravity, undrained shear strength, density, and water content) were measured. Based on the energy analysis and present test data, an empirical formula to predict the penetration depth of torpedo anchor in two-layered soil bed was proposed. The proposed formula was extensively validated by laboratory and field data of previous researchers. The results were in good agreement with those obtained for two-layered and single-layered soil bed.Finally, a sensitivity analysis on the parameters in the formula was performed.
基金Project supported by the National Basic Research Program of China (Grant No. 2011CB403501)the National Natural Science Foundation of China (GrantNos. 41175058,41275062,and 11202106)
文摘A weak nonlinear model of a two-layer barotropic ocean with Rayleigh dissipation is built.The analytic asymptotic solution is derived in the mid-latitude stationary wind field,and the physical meaning of the corresponding problem is discussed.
基金sponsored by the National Basic Research Program of China(973 Program,Grant No.2014CB046203)the National Natural Science Foundation of China(Grant No.11072140)
文摘The hydroelastic response of a circular, very large floating structure(VLFS), idealized as a floating circular elastic thin plate, is investigated for the case of time-harmonic incident waves of the surface and interfacial wave modes, of a given wave frequency, on a two-layer fluid of finite and constant depth. In linear potential-flow theory, with the aid of angular eigenfunction expansions, the diffraction potentials can be expressed by the Bessel functions. A system of simultaneous equations is derived by matching the velocity and the pressure between the open-water and the platecovered regions, while incorporating the edge conditions of the plate. Then the complex nested series are simplified by utilizing the orthogonality of the vertical eigenfunctions in the open-water region. Numerical computations are presented to investigate the effects of different physical quantities, such as the thickness of the plate, Young’s modulus, the ratios of the densities and of the layer depths, on the dispersion relations of the flexural-gravity waves for the two-layer fluid. Rapid convergence of the method is observed, but is slower at higher wave frequency. At high frequency, it is found that there is some energy transferred from the interfacial mode to the surface mode.
基金the National Natural Science Foundation of China(61933010)the Natural Science Basic Research Plan in Shaanxi Province of China(2023-JC-QN-0733).
文摘This paper tackles the formation-containment control problem of fixed-wing unmanned aerial vehicle(UAV)swarm with model uncertainties for dynamic target tracking in three-dimensional space in the faulty case of UAVs’actuator and sensor.The fixed-wing UAV swarm under consideration is organized as a“multi-leader-multi-follower”structure,in which only several leaders can obtain the dynamic target information while others only receive the neighbors’information through the communication network.To simultaneously realize the formation,containment,and dynamic target tracking,a two-layer control framework is adopted to decouple the problem into two subproblems:reference trajectory generation and trajectory tracking.In the upper layer,a distributed finite-time estimator(DFTE)is proposed to generate each UAV’s reference trajectory in accordance with the control objective.Subsequently,a distributed composite robust fault-tolerant trajectory tracking controller is developed in the lower layer,where a novel adaptive extended super-twisting(AESTW)algorithm with a finite-time extended state observer(FTESO)is involved in solving the robust trajectory tracking control problem under model uncertainties,actuator,and sensor faults.The proposed controller simultaneously guarantees rapidness and enhances the system’s robustness with fewer chattering effects.Finally,corresponding simulations are carried out to demonstrate the effectiveness and competitiveness of the proposed two-layer fault-tolerant cooperative control scheme.
文摘Tanlu fault zone(TLFZ)is the largest active fault zone in eastern China.It is characterized by complex tectonic evolution and multiple faults and marks the boundary between the North and South China blocks.An indepth understanding of the distinct crustal structures of both parts of the TLFZ will provide valuable insights into the lithospheric and crustal thinning in eastern China,extensive magmatism since the Mesozoic,and formation mechanisms of metallogenic belts along the Yangtze River.In this study,a two-layer H-κstacking approach was adopted to estimate the thicknesses of the sediment and crystalline crust as well as the corresponding vP/vS ratios based on high-quality teleseismic P-wave receiver functions recorded by permanent and temporary stations in and around the TLFZ.The geological units in the study region were delineated,especially the crustal structures beneath extensive sedimentary basins on both sides of the TLFZ.The following conclusions can be drawn:(1)The crustal thickness in and around the TLFZ greatly varies depending on the segment.In the northern segment,the crust is relatively thin beneath the eastern part of the Songliao Basin,a broad uplift of the Moho can be observed,and the Moho descends from south to north.The crust below the central and southern segments becomes thinner from west to east.The thickness of the crust is less than 30 km toward the eastern side of the boundary between the Jiangsu and Anhui provinces,that is,significantly thinner than in other areas.In terms of the vP/vS ratios,high anomalies were detected in the central-southern segments of the TLFZ,indicating the upwelling of deep mantle magma via deep faults.(2)Positive isostatic gravity anomalies were observed in the eastern part of the northern segment of the TLFZ and in the eastern part of the Suwan segment.The crustal thickness is smaller than that obtained from the Airy model of isostasy.This suggests that the lower crust in this area may have experienced intensive transformation processes,which may be related to crustal thinning(caused by crustal extension)and the strong uplift of the mantle in eastern China.The isostatic gravity anomalies between the eastern and western parts of the TLFZ indicate that the fault zone plays a dominant role in controlling the development of the deep crustal structure.(3)Significant crustal thinning was observed beneath the eastern part of the boundary between the Jiangsu and Anhui provinces in the southern segment of the TLFZ,suggesting that this area is prone to lithospheric thinning of the North China Craton.Due to the subduction,compression,and retreat of the Paleo-Pacific Plate during the Yanshanian Period as well as the dehydration of subducting oceanic crust(within subduction zones),the asthenosphere and oceanic crust in eastern China partially melted,resulting in mantle enrichment.The basic magma from the mantle is accumulated at the base of the crust,leading to magmatic underplating.In areas with weak topography toward the east of the TLFZ,magma rises to the upper crust and surface,resulting in the enrichment of multiple metal deposits in this area.
