Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection ...Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection challenging,they are linked to problems.Diagnostic methods like imaging and tissue biopsy are only effective when the tumor has reached a size that can be identified.The liquid biopsy technique,the least intrusive and most convenient diagnostic method,is the subject of this review.It focuses on the significance of single cell analysis in examining uncommon cancer types.The many biomarkers found in bodily fluids and the cancer types they are linked to in children have been assessed,as has the potential route towards early detection and cancer recurrence forecasting.Combining the single cell liquid biopsy with the newest technologies,such as computational and multi-omics approaches,which have improved the efficiency of processing massive and unique genetic data,appears promising.This article discusses on a number of case reports for uncommon pediatric malignancies,such as Neuroblastoma,Medulloblastoma,Wilms Tumor,Rhabdomyosarcoma,Ewing Sarcoma,and Retinoblastoma,as well as their liquid biopsy profiles.Furthermore,the findings raise ethical questions regarding the therapeutic application of the technology as well as possible difficulties related to clinical translation.The likelihood that this single cell liquid biopsy will be clinically validated and eventually used as a routine diagnostic tool for uncommon pediatric cancers will rise with the realistic approach to sensitivity monitoring,specificity upgrading,and optimization.展开更多
While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfa...While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfacial evaporation offers sustainable management potential,yet inevitable salt nucleation at evaporation interfaces degrades photothermal conversion and operational stability via light scattering and pathway blockage.Inspired by the mangrove leaf,we propose a photothermal 3D polydopamine and polypyrrole polymerized spacer fabric(PPSF)-based upward hanging model evaporation configuration with a reverse water feeding mechanism.This design enables zero-liquiddischarge(ZLD)desalination through phase-separation crystallization.The interconnected porous architecture and the rough surface of the PPSF enable superior water transport,achieving excellent solar-absorbing efficiency of 97.8%.By adjusting the tilt angle(θ),the evaporator separates the evaporation and salt crystallization zones via controlled capillary-driven brine transport,minimizing heat dissipation from brine discharge.At an optimal tilt angle of 52°,the evaporator reaches an evaporation rate of 2.81 kg m^(−2) h^(−1) with minimal heat loss(0.366 W)under 1-sun illumination while treating a 7 wt%waste brine solution.Furthermore,it sustains an evaporation rate of 2.71 kg m^(−2) h^(−1) over 72 h while ensuring efficient salt recovery.These results highlight a scalable,energy-efficient approach for sustainable ZLD desalination.展开更多
The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral bloo...The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.展开更多
A two-component waterborne polyurethane(2K-WPU) was prepared by mixing water-soluble acrylic resin and hexamethylene diisocyanate biuret, and then diluted for phase inversion with water. Compared with water-soluble ac...A two-component waterborne polyurethane(2K-WPU) was prepared by mixing water-soluble acrylic resin and hexamethylene diisocyanate biuret, and then diluted for phase inversion with water. Compared with water-soluble acrylic resin, the phase inversion of 2K-WPU occurs at lower water content. It is indicated by TEM that 2K-WPU parti-cles show a core-shell structure, in which HDI biuret is encapsulated by hydrophilic acrylic resin. 2K-WPU emulsion with HDI biuret has larger particle size and narrower distribution index, while for 2K-WPU emulsion with HDI iso-cyanurate, the latex not only has large particle size, but also has two-peak distribution. FTIR shows that the reaction be-tween HDI biuret and acrylic resin can complete in 12h. In addition, studies on effect of composition of acrylic resin on performance of 2K-WPU show that narrowing the polar difference between water-soluble acrylic resin and HDI biuret and improving the miscibility of two components are the key to prepare the transparent and high gloss films with high crosslinking density.展开更多
Bacillus subtilis strain NCD-2 is an excellent biocontrol agent for plant soil-borne diseases, and the lipopeptide fengycin is one of the active antifungal compounds in strain NCD-2. The regulator PhoP and its sensor ...Bacillus subtilis strain NCD-2 is an excellent biocontrol agent for plant soil-borne diseases, and the lipopeptide fengycin is one of the active antifungal compounds in strain NCD-2. The regulator PhoP and its sensor kinase PhoR compose a two-component system in B. subtilis. In this study, the phoR- and phoP-knockout mutants were constructed by in-frame deletion and the role of PhoR/PhoP on the production of fengycin was determined. Inactivation of phoR or phoP in B. subtilis decreased its inhibition ability against Botrytis cinerea growth in vitro compared to the strain NCD-2 wild type. The lipopeptides were extracted from strain NCD-2 wild type and its mutant strains by hydrochloric acid precipitate, and the lipopeptides from phoR-null mutant orphoP-null mutant almost lost the inhibition ability against B. cinerea growth compared to the lipopeptides from strain NCD-2 wild type. Fast protein liquid chromatography （FPLC） analysis of the lipopeptides showed that inactivation of phoR or phoP genes reduced the production of fengycin by strain NCD-2. The fengycin production abilities were compared for bacteria under low-phosphate medium （LPM） and high-phosphate medium （HPM）, respectively. Results indicated that the regulation of fengycin production by the PhoR/PhoP two-component system occurred in LPM but not in HPM. Reverse transcriptionaI-PCR confirmed that the fengycin synthetase gene fenC was positively regulated by phoP when cultured in LPM. All of these characteristics could be partially restored by complementation of intact phoR or phoP gene in the mutant. These data indicated that the PhoR/PhoP two-component system greatly regulated fengycin production and antifungal ability in B. subtilis NCD-2 mainly under low-phosphate conditions.展开更多
The modulational instability of two-component Bose-Einstein condensates(BECs)under an external parabolic potential is discussed.Based on the trapped two-component Gross-Pitaevskill equations,a time-dependent dispersio...The modulational instability of two-component Bose-Einstein condensates(BECs)under an external parabolic potential is discussed.Based on the trapped two-component Gross-Pitaevskill equations,a time-dependent dispersion relation is obtained analytically by means of the modified lens-type transformation and linear stability analysis.It is shown that a modulational unstable time scale exists for trapped two-component BECs.The modulational properties-which are determined by the wave number,external trapping parameter,intraand inter-species atomic interactions-are modified significantly.The analytical results are confirmed by direct numerical simulation.Our results provide a criterion for judging the occurrence of instability of the trapped two-component BECs in experiment.展开更多
It is shown that the two-component Camassa-Holm and Hunter-Saxton systems are geometrically integrable, namely they describe pseudo-spherical surfaces. As a consequence, their infinite number of conservation laws are ...It is shown that the two-component Camassa-Holm and Hunter-Saxton systems are geometrically integrable, namely they describe pseudo-spherical surfaces. As a consequence, their infinite number of conservation laws are directly constructed. In addition, a class of nonlocal symmetries depending on the pseudo-potentials are obtained.展开更多
In this article, we consider a two-component nonlinear shallow water system, which includes the famous 2-component Camassa-Holm and Degasperis-Procesi equations as special cases. The local well-posedess for this equat...In this article, we consider a two-component nonlinear shallow water system, which includes the famous 2-component Camassa-Holm and Degasperis-Procesi equations as special cases. The local well-posedess for this equations is established. Some sufficient conditions for blow-up of the solutions in finite time are given. Moreover, by separation method, the self-similar solutions for the nonlinear shallow water equations are obtained, and which local or global behavior can be determined by the corresponding Emden equation.展开更多
The paper deals with analytical models of the elastic energy gradient Wsq representing an energy barrier. The energy barrier is a surface integral of the elastic energy density Wq. The elastic energy density is induce...The paper deals with analytical models of the elastic energy gradient Wsq representing an energy barrier. The energy barrier is a surface integral of the elastic energy density Wq. The elastic energy density is induced by thermal stresses acting in an isotropic spherical particle （q = p） with the radius R and in a cubic cell of an isotropic matrix （q = m）. The spherical particle and the matrix are components of a multi-particle-matrix system representing a model system applicable to a real two-component material of a precipitation-matrix type. The multi-particle-matrix system thus consists of periodically distributed isotropic spherical particles and an isotropic infinite matrix. The infinite matrix is imaginarily divided into identical cubic cells with a central spherical particle in each of the cubic cells. The dimension d of the cubic cell then corresponds to an inter-particle distance. The parameters R, d along with the particle volume fraction v = v（R, d） as a function of R, d represent micro- structural characteristics of a real two-component material. The thermal stresses are investigated within the cubic cell, and accordingly are functions of the microstructural charac- teristics. The thermal stresses originate during a cooling pro- cess as a consequence of the difference am - ap in thermal expansion coefficients between the matrix and the particle, am and ap, respectively. The energy barrier Wsq is used for the determination of the thermal-stress induced strengthening aq. The strengthening represents resistance against com- pressive or tensile mechanical loading for am - ap 〉 0 or am - ap 〈 0. respectively.展开更多
We present several families of exact solutions to a system of coupled nonlinear Schrodinger equations. The model describes a binary mixture of two Bose-Einstein condensates in a magnetic trap potential. Using a mappin...We present several families of exact solutions to a system of coupled nonlinear Schrodinger equations. The model describes a binary mixture of two Bose-Einstein condensates in a magnetic trap potential. Using a mapping deformation method, we find exact periodic wave and soliton solutions, including bright and dark soliton pairs.展开更多
Nickel-coated graphite particles and two-component silicone-rubber were compounded to form a conductive composite system. The electrical volume resistivity of the composites were examined and compared under constant t...Nickel-coated graphite particles and two-component silicone-rubber were compounded to form a conductive composite system. The electrical volume resistivity of the composites were examined and compared under constant tensile strains, cyclic heating-cooling, electric field and repeated cyclic tensile strains in order to study the mechanism of electrical conductivity behaviors of the conductive composites under stress, temperature and current. The results showed that a peak value of the electrical resistivity appeared previously and then gradually increasing with increasing tensile strain. The electrical resistivity displayed positive temperature coefficient effect during the temperature increasing and decreasing. Applying 5A direct current to the conductive composites lesulted in an increase in the electrical resistance immediately, but no changes were detected under lower currents. Under the repeated cyclic strain, the peak value of the electrical resistivity of each cycle increased with the test cycle. All the electrical resistivity changes were attributed to the conductive networks broken-up and rebuilt in the conductive composites.展开更多
Ultrasonic Lamb waves are considered as a sensitive and effective tool for nondestructive testing and evaluation of plate-like or pipe-like structures. The nature of multimode and dispersion causes the wave packets to...Ultrasonic Lamb waves are considered as a sensitive and effective tool for nondestructive testing and evaluation of plate-like or pipe-like structures. The nature of multimode and dispersion causes the wave packets to spread, and the modes overlap in both time and frequency domains as they propagate through the structures. By using a two-component laser interferometer technique, in combination with a priori knowledge of the dispersion characteristics and wave structure information of Lamb wave modes, a two-component signal processing technique is presented for implementing dispersion removal and mode separation simultaneously for two modes mixture signals of Lamb waves. The proposed algorithm is first processed and verified using synthetic Lamb wave signals. Then, the two-component displacements test experiment is conducted using different aluminum plate samples. Moreover, we confirm the effectiveness and robustness of this method.展开更多
Invariant subspace method is exploited to obtain exact solutions of the two- component b-family system. It is shown that the two-component b-family system admits the generalized functional separable solutions. Further...Invariant subspace method is exploited to obtain exact solutions of the two- component b-family system. It is shown that the two-component b-family system admits the generalized functional separable solutions. Furthermore, blow up and behavior of those exact solutions are also investigated.展开更多
This article is concerned with the existence of global attractor of a weakly dissipative generalized two-component μ-Hunter-Saxton （gμHS2） system with viscous terms. Under the period boundary conditions and with t...This article is concerned with the existence of global attractor of a weakly dissipative generalized two-component μ-Hunter-Saxton （gμHS2） system with viscous terms. Under the period boundary conditions and with the help of the Galerkin procedure and compactness method, we first investigate the existence of global solution for the viscous weakly dissipative （gμHS2） system. On the basis of some uniformly prior estimates of the solution to the viscous weakly dissipative （gμHS2） system, we show that the semi-group of the solution operator {S（t）}t≥0 has a bounded absorbing set. Moreover, we prove that the dynamical system {S（t）}t≥0 possesses a global attractor in the Sobolev space H2（S） × H2（S）.展开更多
We formulate a matrix Riemann-Hilbert problem to the initial value problem for the two-component system proposed by Matsuno. By solving the associated Riemann-Hilbert problem, we can get the soliton solutions of the t...We formulate a matrix Riemann-Hilbert problem to the initial value problem for the two-component system proposed by Matsuno. By solving the associated Riemann-Hilbert problem, we can get the soliton solutions of the two-component system. One and two soliton solutions are investigated in detail.展开更多
In this paper, isophorone diisocyanate (IPDI), polyethylene glycol (PEG), dimethylolpropionic acid (DMPA) and internal crosslinking agent trimethylolpropane (TMP) were used to prepare waterborne polyurethane. And then...In this paper, isophorone diisocyanate (IPDI), polyethylene glycol (PEG), dimethylolpropionic acid (DMPA) and internal crosslinking agent trimethylolpropane (TMP) were used to prepare waterborne polyurethane. And then double-crosslinked polyurethane-acrylic composite aqueous dispersion was prepared in which polyacrylate was adopted to modify waterborne polyurethane and some special external crosslinking agents were added including silicone and trifunctional aziridine. The influence of the amounts of internal and external crosslinking agents, emulsifier, initiator on the particle size, particle size distribution, viscosity, molecular weight, as well as water adsorption ratio were studied.展开更多
The paper deals with analytical fracture mechanics to consider elastic thermal stresses acting in an isotropic multi-particle-matrix system. The multi-particle-matrix system consists of periodically distributed spheri...The paper deals with analytical fracture mechanics to consider elastic thermal stresses acting in an isotropic multi-particle-matrix system. The multi-particle-matrix system consists of periodically distributed spherical particles in an infinite matrix. The thermal stresses originate during a cooling process as a consequence of the difference αm - αp in thermal expansion coefficients between the matrix and the particle, αm and αp, respectively. The multi-particle-matrix system thus represents a model system applicable to a real two-component material of a precipitation-matrix type. The infinite matrix is imaginarily divided into identical cubic cells. Each of the cubic cells with the dimension d contains a central spherical particle with the radius R, where d thus corresponds to inter-particle distance. The parameters R, d along with the particle volume fraction v = v（R, d） as a function of R, d represent microstructural characteristics of a twocomponent material. The thermal stresses are investigated within the cubic cell, and accordingly are functions of the microstructural characteristics. The analytical fracture mechanics includes an analytical analysis of the crack initiation and consequently the crack propagation both considered for the spherical particle （q = p） and the cell matrix （q = m）. The analytical analysis is based on the determination of the curve integral Wcq of the thermal-stress induced elastic energy density Wq. The crack initiation is represented by the determination of the critical particle radius Rqc = Rqc（V）. Formulae for Rqc are valid for any two-component mate- rial of a precipitate-matrix type. The crack propagation for R 〉 Rqc is represented by the determination of the function fq describing a shape of the crack in a plane perpendicular展开更多
We investigate modulational instability(MI) of a coupled two-component Bose–Einstein condensates in a rotating ring trap. The excitation spectrum and the MI condition of the system are presented analytically. We find...We investigate modulational instability(MI) of a coupled two-component Bose–Einstein condensates in a rotating ring trap. The excitation spectrum and the MI condition of the system are presented analytically. We find that the coupling between the two components strongly modifies the MI condition, and the MI condition is phase-dependent.Furthermore, we discuss the effect of MI on both density excitation and spin excitation. If the inter- and intra-component interaction strengths are all equal, the MI causes density excitation but not spin excitation, and if the inter- and intracomponent interaction strengths are different, the MI causes both density excitation and spin excitation. Our results provide a promising approach for controlling the stability and excitation of a rotating two-component Bose–Einstein condensates by modulating its coupling strength and interaction strength.展开更多
Wave properties of solitons in a two-component Bose-Einstein condensate are investigated in detail.We demonstrate that dark solitons in one of components admit interference and tunneling behavior,in sharp contrast to ...Wave properties of solitons in a two-component Bose-Einstein condensate are investigated in detail.We demonstrate that dark solitons in one of components admit interference and tunneling behavior,in sharp contrast to the scalar dark solitons and vector dark solitons.Analytic analyses of interference properties show that spatial interference patterns are determined by the relative velocity of solitons,while temporal interference patterns depend on the velocities and widths of two solitons,differing from the interference properties of scalar bright solitons.Especially,for an attractive interactions system,we show that interference effects between the two dark solitons can induce some short-time density humps(whose densities are higher than background density).Moreover,the maximum hump value is remarkably sensitive to the variation of the solitons'parameters.For a repulsive interactions system,the temporal-spatial interference periods of dark-bright solitons have lower limits.Numerical simulation results suggest that interference patterns for the dark-bright solitons are more robust against noises than bright-dark solitons.These explicit interference properties can be used to measure the velocities and widths of solitons.It is expected that these interference behaviors can be observed experimentally and can be used to design matter wave soliton interferometer in vector systems.展开更多
文摘Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection challenging,they are linked to problems.Diagnostic methods like imaging and tissue biopsy are only effective when the tumor has reached a size that can be identified.The liquid biopsy technique,the least intrusive and most convenient diagnostic method,is the subject of this review.It focuses on the significance of single cell analysis in examining uncommon cancer types.The many biomarkers found in bodily fluids and the cancer types they are linked to in children have been assessed,as has the potential route towards early detection and cancer recurrence forecasting.Combining the single cell liquid biopsy with the newest technologies,such as computational and multi-omics approaches,which have improved the efficiency of processing massive and unique genetic data,appears promising.This article discusses on a number of case reports for uncommon pediatric malignancies,such as Neuroblastoma,Medulloblastoma,Wilms Tumor,Rhabdomyosarcoma,Ewing Sarcoma,and Retinoblastoma,as well as their liquid biopsy profiles.Furthermore,the findings raise ethical questions regarding the therapeutic application of the technology as well as possible difficulties related to clinical translation.The likelihood that this single cell liquid biopsy will be clinically validated and eventually used as a routine diagnostic tool for uncommon pediatric cancers will rise with the realistic approach to sensitivity monitoring,specificity upgrading,and optimization.
基金supported by National Key Research and Development Program of China(2022YFB3804902,2022YFB3804900)the National Natural Science Foundation of China(52203226,52161145406,42376045)the Fundamental Research Funds for the Central Universities(2232024Y-01,2232025D-02).
文摘While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfacial evaporation offers sustainable management potential,yet inevitable salt nucleation at evaporation interfaces degrades photothermal conversion and operational stability via light scattering and pathway blockage.Inspired by the mangrove leaf,we propose a photothermal 3D polydopamine and polypyrrole polymerized spacer fabric(PPSF)-based upward hanging model evaporation configuration with a reverse water feeding mechanism.This design enables zero-liquiddischarge(ZLD)desalination through phase-separation crystallization.The interconnected porous architecture and the rough surface of the PPSF enable superior water transport,achieving excellent solar-absorbing efficiency of 97.8%.By adjusting the tilt angle(θ),the evaporator separates the evaporation and salt crystallization zones via controlled capillary-driven brine transport,minimizing heat dissipation from brine discharge.At an optimal tilt angle of 52°,the evaporator reaches an evaporation rate of 2.81 kg m^(−2) h^(−1) with minimal heat loss(0.366 W)under 1-sun illumination while treating a 7 wt%waste brine solution.Furthermore,it sustains an evaporation rate of 2.71 kg m^(−2) h^(−1) over 72 h while ensuring efficient salt recovery.These results highlight a scalable,energy-efficient approach for sustainable ZLD desalination.
基金supported by Department of Defense grant HT9425-24-1-0030 a grant from the Stanley Medical Research Institute(to SS).
文摘The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.
文摘A two-component waterborne polyurethane(2K-WPU) was prepared by mixing water-soluble acrylic resin and hexamethylene diisocyanate biuret, and then diluted for phase inversion with water. Compared with water-soluble acrylic resin, the phase inversion of 2K-WPU occurs at lower water content. It is indicated by TEM that 2K-WPU parti-cles show a core-shell structure, in which HDI biuret is encapsulated by hydrophilic acrylic resin. 2K-WPU emulsion with HDI biuret has larger particle size and narrower distribution index, while for 2K-WPU emulsion with HDI iso-cyanurate, the latex not only has large particle size, but also has two-peak distribution. FTIR shows that the reaction be-tween HDI biuret and acrylic resin can complete in 12h. In addition, studies on effect of composition of acrylic resin on performance of 2K-WPU show that narrowing the polar difference between water-soluble acrylic resin and HDI biuret and improving the miscibility of two components are the key to prepare the transparent and high gloss films with high crosslinking density.
基金funded by the earmarked fund for the China Agriculture Research System (CARS-18-15)the National Natural Science Foundation of China (31272085,31572051)the Special Fund for Agro-scientific Research in the Public Interest,China (201503109)
文摘Bacillus subtilis strain NCD-2 is an excellent biocontrol agent for plant soil-borne diseases, and the lipopeptide fengycin is one of the active antifungal compounds in strain NCD-2. The regulator PhoP and its sensor kinase PhoR compose a two-component system in B. subtilis. In this study, the phoR- and phoP-knockout mutants were constructed by in-frame deletion and the role of PhoR/PhoP on the production of fengycin was determined. Inactivation of phoR or phoP in B. subtilis decreased its inhibition ability against Botrytis cinerea growth in vitro compared to the strain NCD-2 wild type. The lipopeptides were extracted from strain NCD-2 wild type and its mutant strains by hydrochloric acid precipitate, and the lipopeptides from phoR-null mutant orphoP-null mutant almost lost the inhibition ability against B. cinerea growth compared to the lipopeptides from strain NCD-2 wild type. Fast protein liquid chromatography （FPLC） analysis of the lipopeptides showed that inactivation of phoR or phoP genes reduced the production of fengycin by strain NCD-2. The fengycin production abilities were compared for bacteria under low-phosphate medium （LPM） and high-phosphate medium （HPM）, respectively. Results indicated that the regulation of fengycin production by the PhoR/PhoP two-component system occurred in LPM but not in HPM. Reverse transcriptionaI-PCR confirmed that the fengycin synthetase gene fenC was positively regulated by phoP when cultured in LPM. All of these characteristics could be partially restored by complementation of intact phoR or phoP gene in the mutant. These data indicated that the PhoR/PhoP two-component system greatly regulated fengycin production and antifungal ability in B. subtilis NCD-2 mainly under low-phosphate conditions.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11764039,11847304,11865014,11475027,11274255 and 11305132the Natural Science Foundation of Gansu Province under Grant No 17JR5RA076the Scientific Research Project of Gansu Higher Education under Grant No 2016A-005
文摘The modulational instability of two-component Bose-Einstein condensates(BECs)under an external parabolic potential is discussed.Based on the trapped two-component Gross-Pitaevskill equations,a time-dependent dispersion relation is obtained analytically by means of the modified lens-type transformation and linear stability analysis.It is shown that a modulational unstable time scale exists for trapped two-component BECs.The modulational properties-which are determined by the wave number,external trapping parameter,intraand inter-species atomic interactions-are modified significantly.The analytical results are confirmed by direct numerical simulation.Our results provide a criterion for judging the occurrence of instability of the trapped two-component BECs in experiment.
基金Supported by the China NSF for Distinguished Young Scholars under Grant No.10925104
文摘It is shown that the two-component Camassa-Holm and Hunter-Saxton systems are geometrically integrable, namely they describe pseudo-spherical surfaces. As a consequence, their infinite number of conservation laws are directly constructed. In addition, a class of nonlocal symmetries depending on the pseudo-potentials are obtained.
基金supported by NSF of China (11071266)partially supported by Scholarship Award for Excellent Doctoral Student granted by Ministry of Educationpartially supported by the found of Chongqing Normal University (13XLB006)
文摘In this article, we consider a two-component nonlinear shallow water system, which includes the famous 2-component Camassa-Holm and Degasperis-Procesi equations as special cases. The local well-posedess for this equations is established. Some sufficient conditions for blow-up of the solutions in finite time are given. Moreover, by separation method, the self-similar solutions for the nonlinear shallow water equations are obtained, and which local or global behavior can be determined by the corresponding Emden equation.
基金supported by the Slovak Research and Development Agency under the contracts No.COST-0022-06, No.COST-0042-06,No.APVV-51-061505,No.APVV-0034-07,No. APVV-0171-06by the 6th FP EU NESPA+16 种基金by FP7-REGPOT-2007- 3 DEMATEN 204953(05/08-04/11)by IMPROVING 229625by HANCOC-MNT.ERA-NET 01/09-12/11by NANOSMART Centre of Excellence(01/2007-12/2010) Slovak Academy of Sciencesby the Slovak Grant Agency VEGA(2/7197/27,2/7194/27,2/7195/27, 1/4107/07)by iNTeg-Risk CP-IP 213345-2by European Structural Fund-Center of Excellence(Progressive Materials with Nano-and Submicron-Structure):ITMS NFP code 262200120019by COST Action 536by COST Action 538by OTKA Foundation(No.T043704, T043685,T 048593,T 63609)by HPRT-CT-2000-00037by EC5 Center of Excellence ICAI-CT-2000-70029by OTKA Postdoctoral Research Grant(D38478)by Swedish Research Council(No.621- 2002-4299)by NSF-OTKA-MTA(No.MTA:96 OTKA:049953)by GVOP-3.2.1.-2004-04-0224/3.0by János Bolyai Research Grant. 96/OTKA:049953,OTKA 63609
文摘The paper deals with analytical models of the elastic energy gradient Wsq representing an energy barrier. The energy barrier is a surface integral of the elastic energy density Wq. The elastic energy density is induced by thermal stresses acting in an isotropic spherical particle （q = p） with the radius R and in a cubic cell of an isotropic matrix （q = m）. The spherical particle and the matrix are components of a multi-particle-matrix system representing a model system applicable to a real two-component material of a precipitation-matrix type. The multi-particle-matrix system thus consists of periodically distributed isotropic spherical particles and an isotropic infinite matrix. The infinite matrix is imaginarily divided into identical cubic cells with a central spherical particle in each of the cubic cells. The dimension d of the cubic cell then corresponds to an inter-particle distance. The parameters R, d along with the particle volume fraction v = v（R, d） as a function of R, d represent micro- structural characteristics of a real two-component material. The thermal stresses are investigated within the cubic cell, and accordingly are functions of the microstructural charac- teristics. The thermal stresses originate during a cooling pro- cess as a consequence of the difference am - ap in thermal expansion coefficients between the matrix and the particle, am and ap, respectively. The energy barrier Wsq is used for the determination of the thermal-stress induced strengthening aq. The strengthening represents resistance against com- pressive or tensile mechanical loading for am - ap 〉 0 or am - ap 〈 0. respectively.
基金Project supported by the National Natural Science Foundation of China（Grant Nos 10575087 and 10302018）, and the Natural Science Foundation of Zhejiang Province, China （Grant No Y605056）.
文摘We present several families of exact solutions to a system of coupled nonlinear Schrodinger equations. The model describes a binary mixture of two Bose-Einstein condensates in a magnetic trap potential. Using a mapping deformation method, we find exact periodic wave and soliton solutions, including bright and dark soliton pairs.
基金Funded by Wuhan Science and Technology Bureau (No.200710321090-18)
文摘Nickel-coated graphite particles and two-component silicone-rubber were compounded to form a conductive composite system. The electrical volume resistivity of the composites were examined and compared under constant tensile strains, cyclic heating-cooling, electric field and repeated cyclic tensile strains in order to study the mechanism of electrical conductivity behaviors of the conductive composites under stress, temperature and current. The results showed that a peak value of the electrical resistivity appeared previously and then gradually increasing with increasing tensile strain. The electrical resistivity displayed positive temperature coefficient effect during the temperature increasing and decreasing. Applying 5A direct current to the conductive composites lesulted in an increase in the electrical resistance immediately, but no changes were detected under lower currents. Under the repeated cyclic strain, the peak value of the electrical resistivity of each cycle increased with the test cycle. All the electrical resistivity changes were attributed to the conductive networks broken-up and rebuilt in the conductive composites.
基金Project supported by the National Natural Science Foundation of China(Grant No.11374230)
文摘Ultrasonic Lamb waves are considered as a sensitive and effective tool for nondestructive testing and evaluation of plate-like or pipe-like structures. The nature of multimode and dispersion causes the wave packets to spread, and the modes overlap in both time and frequency domains as they propagate through the structures. By using a two-component laser interferometer technique, in combination with a priori knowledge of the dispersion characteristics and wave structure information of Lamb wave modes, a two-component signal processing technique is presented for implementing dispersion removal and mode separation simultaneously for two modes mixture signals of Lamb waves. The proposed algorithm is first processed and verified using synthetic Lamb wave signals. Then, the two-component displacements test experiment is conducted using different aluminum plate samples. Moreover, we confirm the effectiveness and robustness of this method.
基金supported by NSFC(11471260)the Foundation of Shannxi Education Committee(12JK0850)
文摘Invariant subspace method is exploited to obtain exact solutions of the two- component b-family system. It is shown that the two-component b-family system admits the generalized functional separable solutions. Furthermore, blow up and behavior of those exact solutions are also investigated.
基金partially supported by NNSF of China(11571126,11701198)China Postdoctoral Science Foundation funded project(2017M622397)
文摘This article is concerned with the existence of global attractor of a weakly dissipative generalized two-component μ-Hunter-Saxton （gμHS2） system with viscous terms. Under the period boundary conditions and with the help of the Galerkin procedure and compactness method, we first investigate the existence of global solution for the viscous weakly dissipative （gμHS2） system. On the basis of some uniformly prior estimates of the solution to the viscous weakly dissipative （gμHS2） system, we show that the semi-group of the solution operator {S（t）}t≥0 has a bounded absorbing set. Moreover, we prove that the dynamical system {S（t）}t≥0 possesses a global attractor in the Sobolev space H2（S） × H2（S）.
文摘We formulate a matrix Riemann-Hilbert problem to the initial value problem for the two-component system proposed by Matsuno. By solving the associated Riemann-Hilbert problem, we can get the soliton solutions of the two-component system. One and two soliton solutions are investigated in detail.
文摘In this paper, isophorone diisocyanate (IPDI), polyethylene glycol (PEG), dimethylolpropionic acid (DMPA) and internal crosslinking agent trimethylolpropane (TMP) were used to prepare waterborne polyurethane. And then double-crosslinked polyurethane-acrylic composite aqueous dispersion was prepared in which polyacrylate was adopted to modify waterborne polyurethane and some special external crosslinking agents were added including silicone and trifunctional aziridine. The influence of the amounts of internal and external crosslinking agents, emulsifier, initiator on the particle size, particle size distribution, viscosity, molecular weight, as well as water adsorption ratio were studied.
基金supported by the Slovak Research and Development Agency under the contracts No. COST-0022-06, No.COST-0042-06, No. APVV-51-061505, No. APVV-0034-07, No.APVV-0171-06by the 6th FP EU NESPA+17 种基金by FP7-EGPOT-2007-3 DEMATEN 204953 (05/08-04/11)by IMPROVING 229625by HANCOC-MNT.ERA-NET 01/09-12/11by NANOSMART Centre of Excellence (01/2007-12/2010) Slovak Academy of Sciencesby the Slovak Grant Agency VEGA (2/7197/27, 2/7194/27, 2/7195/27,1/4107/07)by iNTeg-Risk CP-IP 213345-2by European Structural Fund-Center of Excellence (Progressive Materials with Nano-and Submicron-Structure): ITMS NFP code 262200120019by COST Action 536by COST Action 538by OTKA Foundation (No. T043704,T043685, T 048593, T 63609)by HPRT-CT-2000-00037by EC5 Center of Excellence ICAI-CT-2000-70029by OTKA Postdoctoral Research Grant (D38478)by Swedish Research Council (No. 621-2002-4299)by NSF-OTKA-MTA (No. MTA: 96 OTKA: 049953)by GVOP-3.2.1.-2004-04-0224/3.0by Janos Bolyai Research Grant.96/OTKA04953, OTKA 63609.
文摘The paper deals with analytical fracture mechanics to consider elastic thermal stresses acting in an isotropic multi-particle-matrix system. The multi-particle-matrix system consists of periodically distributed spherical particles in an infinite matrix. The thermal stresses originate during a cooling process as a consequence of the difference αm - αp in thermal expansion coefficients between the matrix and the particle, αm and αp, respectively. The multi-particle-matrix system thus represents a model system applicable to a real two-component material of a precipitation-matrix type. The infinite matrix is imaginarily divided into identical cubic cells. Each of the cubic cells with the dimension d contains a central spherical particle with the radius R, where d thus corresponds to inter-particle distance. The parameters R, d along with the particle volume fraction v = v（R, d） as a function of R, d represent microstructural characteristics of a twocomponent material. The thermal stresses are investigated within the cubic cell, and accordingly are functions of the microstructural characteristics. The analytical fracture mechanics includes an analytical analysis of the crack initiation and consequently the crack propagation both considered for the spherical particle （q = p） and the cell matrix （q = m）. The analytical analysis is based on the determination of the curve integral Wcq of the thermal-stress induced elastic energy density Wq. The crack initiation is represented by the determination of the critical particle radius Rqc = Rqc（V）. Formulae for Rqc are valid for any two-component mate- rial of a precipitate-matrix type. The crack propagation for R 〉 Rqc is represented by the determination of the function fq describing a shape of the crack in a plane perpendicular
基金Supported by the National Natural Science Foundation of China under Grant No.11465008the Hunan Provincial Natural Science Foundation under Grant No.2015JJ2114+2 种基金the Scientific Research Fund of Hunan Provincial Education Department under Grant Nos.14A118,13C881Science and Technology Innovative Research Team in Higher Educational Instituions of Hunan ProvinceScience Research Foundation of Xiangnan University under Grant No.2012–126(41)
文摘We investigate modulational instability(MI) of a coupled two-component Bose–Einstein condensates in a rotating ring trap. The excitation spectrum and the MI condition of the system are presented analytically. We find that the coupling between the two components strongly modifies the MI condition, and the MI condition is phase-dependent.Furthermore, we discuss the effect of MI on both density excitation and spin excitation. If the inter- and intra-component interaction strengths are all equal, the MI causes density excitation but not spin excitation, and if the inter- and intracomponent interaction strengths are different, the MI causes both density excitation and spin excitation. Our results provide a promising approach for controlling the stability and excitation of a rotating two-component Bose–Einstein condensates by modulating its coupling strength and interaction strength.
基金Project supported by the National Natural Science Foundation of China(Grant No.11775176)the Basic Research Program of the Natural Science of Shaanxi Province,China(Grant No.2018KJXX-094)+1 种基金the Key Innovative Research Team of Quantum Many-Body Theory and Quantum Control in Shaanxi Province,China(Grant No.2017KCT-12)the Major Basic Research Program of the Natural Science of Shaanxi Province,China(Grant No.2017ZDJC-32).
文摘Wave properties of solitons in a two-component Bose-Einstein condensate are investigated in detail.We demonstrate that dark solitons in one of components admit interference and tunneling behavior,in sharp contrast to the scalar dark solitons and vector dark solitons.Analytic analyses of interference properties show that spatial interference patterns are determined by the relative velocity of solitons,while temporal interference patterns depend on the velocities and widths of two solitons,differing from the interference properties of scalar bright solitons.Especially,for an attractive interactions system,we show that interference effects between the two dark solitons can induce some short-time density humps(whose densities are higher than background density).Moreover,the maximum hump value is remarkably sensitive to the variation of the solitons'parameters.For a repulsive interactions system,the temporal-spatial interference periods of dark-bright solitons have lower limits.Numerical simulation results suggest that interference patterns for the dark-bright solitons are more robust against noises than bright-dark solitons.These explicit interference properties can be used to measure the velocities and widths of solitons.It is expected that these interference behaviors can be observed experimentally and can be used to design matter wave soliton interferometer in vector systems.
