CRISPR/Cas9-mediated genome engineering technologies are now widely applied in various organisms,including mouse and human cells（Cong et al.,2013;Mali et al.,2013;Yang et al.,2013;Hsu et al.,2014）.The most widely us...CRISPR/Cas9-mediated genome engineering technologies are now widely applied in various organisms,including mouse and human cells（Cong et al.,2013;Mali et al.,2013;Yang et al.,2013;Hsu et al.,2014）.The most widely used customized CRISPR/Cas9（Sp Cas9）is derived from Streptococcus pyogenes（Cong et al.,2013）.展开更多
Real-time, automatic, and accurate determination of seismic signals is critical for rapid earthquake reporting and early warning. In this study, we present a correction trigger function（CTF） for automatically detect...Real-time, automatic, and accurate determination of seismic signals is critical for rapid earthquake reporting and early warning. In this study, we present a correction trigger function（CTF） for automatically detecting regional seismic events and a fourth-order statistics algorithm with the Akaike information criterion（AIC） for determining the direct wave phase, based on the differences, or changes, in energy, frequency, and amplitude of the direct P- or S-waves signal and noise. Simulations suggest for that the proposed fourth-order statistics result in high resolution even for weak signal and noise variations at different amplitude, frequency, and polarization characteristics. To improve the precision of establishing the S-waves onset, first a specific segment of P-wave seismograms is selected and the polarization characteristics of the data are obtained. Second, the S-wave seismograms that contained the specific segment of P-wave seismograms are analyzed by S-wave polarization filtering. Finally, the S-wave phase onset times are estimated. The proposed algorithm was used to analyze regional earthquake data from the Shandong Seismic Network. The results suggest that compared with conventional methods, the proposed algorithm greatly decreased false and missed earthquake triggers, and improved the detection precision of direct P- and S-wave phases.展开更多
In this paper, the roles of low velocity and high conductivity body inside the crust in the process of strong earth quake preparation are approached by using theoretical analysis method based on the comprehensive rese...In this paper, the roles of low velocity and high conductivity body inside the crust in the process of strong earth quake preparation are approached by using theoretical analysis method based on the comprehensive researches on the fine structure of strong seismic source in the North China. The following results are obtained. The low-velocity and high-conductivity body plays the promoting role for the action of deep-seated structure in the medium stage of earthquake preparation, except that its existence is advantageous to the stress concentrating in the overlying brittle layer during the process of earthquake preparation. And it plays the triggering role for the occurrence of strong earthquake in the later stage of earthquake preparation.展开更多
基金supported by the grants from the Natural Science Foundation of China (No.81201181 to F.G.81473295 and 81670882 to Z.M.S and 81700885 to X.L.G.)+5 种基金Zhejiang Provincial & Ministry of Health research fund for medical sciences (WKJ2013-2-023 to F.G.WKJ-ZJ-1828 to J.Z.Z.and 2016KYA145 to X.L.G.)Science Technology Project of Zhejiang Province (2014C33260 to Z.M.S.and 2017C37176 to F.G.)Eye Hospital at Wenzhou Medical University (YNZD201602 to F.G.)Wenzhou City (Y20160008 to J.Z.Z.)Research Fund for Lin He's Academician Workstation of New Medicine and Clinical Translation (17331209 to C.B.L.)
文摘CRISPR/Cas9-mediated genome engineering technologies are now widely applied in various organisms,including mouse and human cells（Cong et al.,2013;Mali et al.,2013;Yang et al.,2013;Hsu et al.,2014）.The most widely used customized CRISPR/Cas9（Sp Cas9）is derived from Streptococcus pyogenes（Cong et al.,2013）.
基金supported by the National Science and Technology Project(Grant No.2012BAK19B04)the Spark Program of Earthquake Sciences,China Earthquake Administration(Grant No.XH12029)
文摘Real-time, automatic, and accurate determination of seismic signals is critical for rapid earthquake reporting and early warning. In this study, we present a correction trigger function（CTF） for automatically detecting regional seismic events and a fourth-order statistics algorithm with the Akaike information criterion（AIC） for determining the direct wave phase, based on the differences, or changes, in energy, frequency, and amplitude of the direct P- or S-waves signal and noise. Simulations suggest for that the proposed fourth-order statistics result in high resolution even for weak signal and noise variations at different amplitude, frequency, and polarization characteristics. To improve the precision of establishing the S-waves onset, first a specific segment of P-wave seismograms is selected and the polarization characteristics of the data are obtained. Second, the S-wave seismograms that contained the specific segment of P-wave seismograms are analyzed by S-wave polarization filtering. Finally, the S-wave phase onset times are estimated. The proposed algorithm was used to analyze regional earthquake data from the Shandong Seismic Network. The results suggest that compared with conventional methods, the proposed algorithm greatly decreased false and missed earthquake triggers, and improved the detection precision of direct P- and S-wave phases.
文摘In this paper, the roles of low velocity and high conductivity body inside the crust in the process of strong earth quake preparation are approached by using theoretical analysis method based on the comprehensive researches on the fine structure of strong seismic source in the North China. The following results are obtained. The low-velocity and high-conductivity body plays the promoting role for the action of deep-seated structure in the medium stage of earthquake preparation, except that its existence is advantageous to the stress concentrating in the overlying brittle layer during the process of earthquake preparation. And it plays the triggering role for the occurrence of strong earthquake in the later stage of earthquake preparation.
