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An FPGA‑based trigger system for CSHINE 被引量:1
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作者 Dong Guo Yu‑Hao Qin +15 位作者 Sheng Xiao Zhi Qin Yi‑Jie Wang Fen‑Hai Guan Xin‑Yue Diao Bo‑Yuan Zhang Yao‑Peng Zhang Da‑Wei Si Shi‑Wei Xu Xiang‑Lun Wei He‑Run Yang Peng Ma Tian‑Li Qiu Hai‑Chuan Zou Li‑Min Duan Zhi‑Gang Xiao 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2022年第12期138-146,共9页
A trigger system of the general function was designed using the commercial module of CAEN V2495 for heavy-ion nuclear reaction experiments at Fermi energies.The system was applied and verified on the compact spectrome... A trigger system of the general function was designed using the commercial module of CAEN V2495 for heavy-ion nuclear reaction experiments at Fermi energies.The system was applied and verified on the compact spectrometer for heavy IoN experiment(CSHINE).Based on the field-programmable logic gate array technology of the command register access and remote computer control operation,trigger functions can be flexibly configured according to experimental physical goals.Using the trigger system on CSHINE,we conducted a beam experiment at 25 MeV/u^(86)Kr+^(124)Sn on the Radioactive Ion Beam Line 1 in Lanzhou,China.The online results demonstrated that the trigger system worked normally and correctly.This system can be extended to other experiments as well. 展开更多
关键词 CSHINE trigger system FPGA Heavy ion experiment
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Research and Application of Seismic Wave Detection Method Based on Delaunay Triangulation in Preventing False Triggers of Earthquake Early Warning Systems
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作者 Sun Lu-Qiang Zheng Guo-Dong +2 位作者 Ma Chao-Qun Wang Ke-Qiang Bai Yun-Peng 《Applied Geophysics》 2025年第3期869-877,898,共10页
The earthquake early warning system is an effective means of disaster reduction to reduce losses caused by earthquakes,it can release earthquake warning information to the public before destructive seismic waves reach... The earthquake early warning system is an effective means of disaster reduction to reduce losses caused by earthquakes,it can release earthquake warning information to the public before destructive seismic waves reach the warning target area,and carry out automatic disposal of lifeline engineering facilities.Through the construction of the National Earthquake Intensity Rapid Reporting and Early Warning Project,an earthquake early warning network consisting of over 1900 monitoring stations has been established in the Beijing-Tianjin-Hebei Urban Agglomeration.The early warning system has achieved second level earthquake warning and minute level intensity rapid reporting.The implementation of these functions relies on the system's ability to timely,accurately,and reliably identify seismic waves.But with the development of social economy,the background noise of earthquake observation environment is becoming increasingly complex,which brings certain challenges to earthquake wave recognition,some interference events have the risk of triggering the earthquake warning system incorrectly.Therefore,this article focuses on seismic wave recognition in complex noise environments and proposes a seismic wave detection method based on triangulation to enhance the antiinterference ability and recognition accuracy of early warning systems. 展开更多
关键词 earthquake warning background noise DELAUNAY false trigger
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Self-Triggered Impulsive Control for Nonlinear Stochastic Systems
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作者 Tao Zhan Yi Ji +2 位作者 Yabin Gao Hongyi Li Yuanqing Xia 《IEEE/CAA Journal of Automatica Sinica》 2025年第1期264-266,共3页
Dear Editor,This letter deals with the stabilization problem of nonlinear stochastic systems via self-triggered impulsive control(STIC), where the timing of impulsive control actions is not dependent on continuous sta... Dear Editor,This letter deals with the stabilization problem of nonlinear stochastic systems via self-triggered impulsive control(STIC), where the timing of impulsive control actions is not dependent on continuous state monitoring. In contrast to the existing self-triggered control method, novel self-triggered mechanism(STM) is proposed by incorporating a waiting time for stabilizing impulses. This allows for direct prediction of the next impulsive instant. 展开更多
关键词 direct prediction next impulsive instant impulsive control stabilization problem nonlinear stochastic systems impulsive control actions self triggered control state monitoring STABILIZATION
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A shock wave overpressure test system based on multiple triggers
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作者 张晋文 王文廉 张志杰 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2015年第1期19-24,共6页
Because single trigger system is unreliable for shock wave overpressure test, this paper presents a multi-trigger overpressure test system. The large memory capacity is divided into parts to achieve data acquisition a... Because single trigger system is unreliable for shock wave overpressure test, this paper presents a multi-trigger overpressure test system. The large memory capacity is divided into parts to achieve data acquisition and storage with multiple triggers. Compared with conventional single-shot storage test system, this system can prevent false trigger and improve reliability of the test. By using explosion time to extract valid signal segments, it improves the efficiency of data recovery. These characteristics of the system contribute to multi-point test. After the dynamic characteristics of the system are calibrated, the valid data can be obtained in explosion experiments. The results show that the multi-trigger test system has higher reliability than single trigger test system. 展开更多
关键词 explosion field overpressure test multiple triggers explosion time extraction
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The trigger system for the external target experiment in the HIRFL cooling storage ring
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作者 李敏 赵雷 +3 位作者 刘金鑫 鲁一鸣 刘树彬 安琪 《Chinese Physics C》 SCIE CAS CSCD 2016年第8期103-109,共7页
A trigger system was designed for the external target experiment in the Cooling Storage Ring (CSR) of the Heavy Ion Research Facility in Lanzhou (HIRFL). Considering that different detectors are scattered over a l... A trigger system was designed for the external target experiment in the Cooling Storage Ring (CSR) of the Heavy Ion Research Facility in Lanzhou (HIRFL). Considering that different detectors are scattered over a large area, the trigger system is designed based on a master-slave structure and fiber-based serial data transmission technique. The trigger logic is organized in hierarchies, and flexible reconfiguration of the trigger function is achieved based on command register access or overall field-programmable gate array (FPGA) logic on-line reconfiguration controlled by remote computers. We also conducted tests to confirm the function of the trigger electronics, and the results indicate that this trigger system works well. 展开更多
关键词 trigger system fiber-based data transmission FPGA RECONFIGURATION
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Fixed-Time Cooperative Tracking for Delayed Disturbed Multi-Agent Systems Under Dynamic Event-Triggered Control 被引量:10
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作者 Jian Liu Yongbao Wu +1 位作者 Mengwei Sun Changyin Sun 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2022年第5期930-933,共4页
Dear editor,Recently,researchers have obtained many new results about the multi-agent systems(MASs)[1]-[3].In[1],the fixed-time cooperative control(FTCC)algorithm of linear MASs with matched disturbances was proposed.... Dear editor,Recently,researchers have obtained many new results about the multi-agent systems(MASs)[1]-[3].In[1],the fixed-time cooperative control(FTCC)algorithm of linear MASs with matched disturbances was proposed.The nonholonomic chained-form dynamics case was considered in[2].In[3],the output tracking problem with data packet dropout was solved for high-order MASs.Moreover,delay frequently occurs because of the non-ideal data transmission[4],and the corresponding FTCC algorithm of MASs with delay was given in[5]. 展开更多
关键词 EDITOR DYNAMIC trigger EVENT
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A reusable planar triggered spark-gap switch batched-fabricated with PCB technology for medium- and low-voltage pulse power systems 被引量:3
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作者 Zhi Yang Ke Wang +5 位作者 Peng Zhu Peng Liu Qiu Zhang Cong Xu Hao-tian Jian Rui-qi Shen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2021年第4期1572-1578,共7页
Triggered spark-gap switch is a popular discharge switch for pulse power systems.Previous studies have focused on planarizing this switch using thin film techniques in order to meet the requirements of compact size in... Triggered spark-gap switch is a popular discharge switch for pulse power systems.Previous studies have focused on planarizing this switch using thin film techniques in order to meet the requirements of compact size in the systems.Such switches are one-shot due to electrodes being too thin to sufficiently resist spark-erosion.Additionally,these switches did not employ any structures in securing internal gas composition,resulting in inconsistent performance under harsh atmospheres.In this work,a novel planar triggered spark-gap switch(PTS)with a hermetically sealed cavity was batched-prepared with printed circuit board(PCB)technology,to achieve reusability with low cost.The proposed PTS was inspected by micro-computed tomography to ensure PCB techniques meet the requirements of machining precision.The results from electrical experiments demonstrated that PCB PTS were consistent and reusable with lifespan over 20 times.The calculated switch voltage and circuit current were consistent with those derived from real-world measurements.Finally,PCB PTS was used to introduce hexanitrostilbene(HNS)pellets in a pulse power system to verify its performance. 展开更多
关键词 Pulse power systems Printed circuit board technology triggered spark-gap switch Planar discharge switch Electrical performance
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Trigger control characteristics of fuze-recoil simulation system based on electromagnetic launcher 被引量:1
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作者 Wenhao Wang Shihua Bi +2 位作者 Hongjun Xiang Chao Zhan Xichao Yuan 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2017年第3期563-571,共9页
Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the a... Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the arm fuze, its dynamic simulation test has always been the focus of the fuze test research. A new fuze recoil environmental simulation method is proposed based on the electromagnetic launcher. Then the trigger control characteristics of the fuze recoil simulation system and the influence of the trigger position on the recoil force are studied. The results of the study show that although the pulse width of the armature force curve can be changed by adjusting the trigger position, due to the limit of the range, there also exists the contradiction that the electromagnetic pulse width gets narrow with the increase of electromagnetic force peak. Thus, it cannot meet the requirements of the fuze launch recoil simulation. In order to make the recoil force close to the actual environment, the multi-stage trigger control characteristics are analyzed, and the influence of trigger position on recoil environmental force characteristics is studied. Then a fuze launch recoil environmental simulation platform is established and continuous electromagnetic force is achieved by using the trigger strategy. Finally, the experiment is performed to simulate the fuze launch recoil environment and show the feasibility and effectiveness of the proposed theoretical analysis. The major research work of this paper includes studying the composition and basic principle of the simulation system, establishing a launch model to analyze the single-stage and multi-stage coil fuze launch recoil characteristics, designing the test device to verify the correctness and validity of the research. This paper draws the conclusions that the feasibility of the fuze launch environmental simulation based on the electromagnetic launcher is verified, the trigger position has a great influence on force peak continuity, the problems of low maximum overload peak and short peak duration in the multi-stage coil fuze launch environmental simulation can be effectively solved through adjusting the trigger position, the system has creative and extensive application prospects. 展开更多
关键词 trigger control fuze-recoil simulation electromagnetic launcher
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Delay Trigger in the Application of Network Testing System 被引量:1
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作者 马敏 严浩 夏侯士戟 《Journal of Donghua University(English Edition)》 EI CAS 2015年第1期132-135,共4页
The researchers who study the local area network( LAN) eXtension for instrumentation( LXI) instrument are pursuing instrument's high-precision synchronization. In the paper,three synchronization modes were discuss... The researchers who study the local area network( LAN) eXtension for instrumentation( LXI) instrument are pursuing instrument's high-precision synchronization. In the paper,three synchronization modes were discussed which were clock synchronization, trigger synchronization, and response synchronization. Synchronous process between LXI instruments was analyzed and each time factor affecting the synchronization accuracy was discussed. On the basis of the analysis,it can be found that delay trigger plays an important role in the network testing system's synchronization. Delay trigger can produce an additional time interval to correct the difference of each LXI instrument's response time. Then,a method to realize the delay trigger was introduced. Delay time can be adjustable according to the actual demand. Finally,synchronization accuracy of network testing system can reach nanoseconds. 展开更多
关键词 LXI instrument synchronization accuracy network testing system delay trigger
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Clock synchronization design and evaluation for trigger-less data acquisition system 被引量:2
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作者 SHANG Linfeng SONG Kezhu CAO Ping 《Nuclear Science and Techniques》 SCIE CAS CSCD 2012年第6期361-368,共8页
For modern particle physics experiments,trigger-less data acquisition(DAQ) system has been put into practice because of the need of reaction multiplicity and trigger flexibility.In such new DAQ systems,global synchron... For modern particle physics experiments,trigger-less data acquisition(DAQ) system has been put into practice because of the need of reaction multiplicity and trigger flexibility.In such new DAQ systems,global synchronized clock plays an important role because it affects the granularity of time slice and precision of reference clock.In this paper,a novel synchronized clock distribution method is proposed.With the help of modulation technique,master clock module distributes system clock to each slave module.To synchronize slave clocks,the propagation delay is adjusted and the clock phase is aligned by an FPGA chip automatically.Furthermore,an ADCbased method is proposed to evaluate the performance of multi-module clock synchronization simultaneously.The experiments of a prototype system show that slave clocks can be synchronized less than 100 ps over 150 m range.The proposed method is simple and flexible,and it can be used in trigger-less DAQ system and other applications of clock distribution preciously. 展开更多
关键词 数据采集系统 同步时钟 同步触发 评估 粒子物理实验 设计 时钟分配 参考时钟
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Excess Heat Triggered by Different Current in a D/Pd Gas-Loading System 被引量:3
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作者 Xin Lu Bingjun Shen +3 位作者 Lihong Jin Xinle Zhao Hongyu Wang Jian Tian 《Journal of Energy and Power Engineering》 2013年第7期1299-1303,共5页
In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants (k = AT//kP... In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants (k = AT//kP) in both nitrogen and deuterium atmosphere we found an optimum current (8 A) and a deuterium pressure (9 x 104 Pa) in which the system could release a maximum excess power (more than 80 W). The reproducibility was 16/16 and the excess energy released in the longest experiment was about 300 MJ within 40 days, which was corresponding to 104 eV for each palladium atom. Analysis of the palladium surface with a SEM (scanning electron microscopy) and an EDS (energy dispersive spectrometer) revealed that some new surface topographical feature with concentrations of unexpected elements (such as Ag, Sn, Pb and Ca) appeared after the current triggering. The results implied that the excess heat might come from a nuclear transmutation. 展开更多
关键词 Current triggering deuterium pressure D/Pd gas-loading system excess heat.
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Design of online control and monitoring software for the CPPF system in the CMS Level-1 trigger upgrade
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作者 Li-Bo Cheng Peng-Cheng Cao +1 位作者 Jing-Zhou Zhao Zhen-An Liu 《Nuclear Science and Techniques》 SCIE CAS CSCD 2018年第11期279-286,共8页
The concentration preprocessing and fan-out(CPPF) system is one of the electronic subsystems of the upgraded Compact Muon Solenoid(CMS) Level-1 trigger system. It includes, in hardware, eight specially designed CPPF c... The concentration preprocessing and fan-out(CPPF) system is one of the electronic subsystems of the upgraded Compact Muon Solenoid(CMS) Level-1 trigger system. It includes, in hardware, eight specially designed CPPF cards, one CMS card called AMC13, one commercial Micro-TCA Carrier HUB(MCH) card, and a MicroTCA shelf. Powerful online software is needed for the system, including providing reliable configuration and monitoring for the hardware, and a graphical interface for executing all actions and publishing monitoring messages.Further, to control and monitor the large amount of homogeneous hardware, the SoftWare Automating conTrol of Common Hardware(SWATCH) concept was proposed and developed. The SWATCH provides a generic structure and is flexible for customization. The structure includes a hardware access library based on the IPbus protocol, which assumes a virtual 32-bit address/32-bit data bus and builds a simple hardware access layer. Furthermore, the structure provides a graphical user interface, which is based on modern web technology and is accessible by web page. The CPPF controlling and monitoring online software was also customized from a common SWATCH cell, and provides afinite state machine(FSM) for configuring the entire CPPF hardware, and five monitoring objects for periodically collecting monitoring data from five main functional modules in the CPPF hardware. This paper introduces the details of the CPPF SWATCH cell development. 展开更多
关键词 CPPF CMS Level-1 trigger SWATCH MONITOR IPbus
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Hybrid-triggered consensus for multi-agent systems with time-delays,uncertain switching topologies, and stochastic cyber-attacks 被引量:1
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作者 Xia Chen Li-Yuan Yin +1 位作者 Yong-Tai Liu Hao Liu 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第9期131-144,共14页
We propose a new approach to discuss the consensus problem of multi-agent systems with time-varying delayed control inputs, switching topologies, and stochastic cyber-attacks under hybrid-triggered mechanism.A Bernoul... We propose a new approach to discuss the consensus problem of multi-agent systems with time-varying delayed control inputs, switching topologies, and stochastic cyber-attacks under hybrid-triggered mechanism.A Bernoulli variable is used to describe the hybrid-triggered scheme, which is introduced to alleviate the burden of the network.The mathematical model of the closed-loop control system is established by taking the influences of time-varying delayed control inputs,switching topologies, and stochastic cyber-attacks into account under the hybrid-triggered scheme.A theorem as the main result is given to make the system consistent based on the theory of Lyapunov stability and linear matrix inequality.Markov jumps with uncertain rates of transitions are applied to describe the switch of topologies.Finally, a simulation example demonstrates the feasibility of the theory in this paper. 展开更多
关键词 hybrid-triggered CONSENSUS multi-agent system time-delay and cyber-attacks switching TOPOLOGIES
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Development of a High Power Programmable Precise Time-Delay Trigger/Ignition System for MFCG
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作者 吴碧 何远航 +1 位作者 张庆明 马月芬 《Journal of Beijing Institute of Technology》 EI CAS 2008年第3期311-315,共5页
High-power precise delay trigger/ignition system is a programmable pulse generator developed for experiment controlling in explosively driven magnetic flux compression generators. Precise delay pulses are generated by... High-power precise delay trigger/ignition system is a programmable pulse generator developed for experiment controlling in explosively driven magnetic flux compression generators. Precise delay pulses are generated by the digital circuit, after being magnified and sharpened through multistage isolated amplifiers and rising edge sharpening device, high-voltage steep delay pulses with precision less than μs level are obtained. This system has been used in our compact magnetic flux compression generator experiments in place of the traditional primaeord delay device. 展开更多
关键词 precision synchronization field distortion switch trigger flux compression generator spark deto-nator ignition rising edge sharpening
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PC synchronization of a class of chaotic systems via event-triggered control 被引量:1
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作者 罗润梓 何龙敏 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第7期323-330,共8页
The PC synchronization of a class of chaotic systems is investigated in this paper. The drive system is assumed to have only one state variable available. By constructing proper observers, some novel criteria for PC s... The PC synchronization of a class of chaotic systems is investigated in this paper. The drive system is assumed to have only one state variable available. By constructing proper observers, some novel criteria for PC synchronization are proposed via event-triggered control scheme. The Lii system and Chen system are taken as examples to demonstrate the efficiency of the proposed approach. 展开更多
关键词 chaotic system state observer event-triggered control
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Self-triggered Consensus Control for Linear Multi-agent Systems With Input Saturation 被引量:16
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作者 Yanxu Su Qingling Wang Changyin Sun 《IEEE/CAA Journal of Automatica Sinica》 EI CSCD 2020年第1期150-157,共8页
In this paper, we study the consensus problem for a class of linear multi-agent systems(MASs) with consideration of input saturation under the self-triggered mechanism. In the context of discrete-time systems, a self-... In this paper, we study the consensus problem for a class of linear multi-agent systems(MASs) with consideration of input saturation under the self-triggered mechanism. In the context of discrete-time systems, a self-triggered strategy is developed to determine the time interval between the adjacent triggers. The triggering condition is designed by using the current sampled consensus error. Furthermore, the consensus control protocol is designed by means of a state feedback approach. It is shown that the considered multi-agent systems can reach consensus with the presented algorithm. Some sufficient conditions are proposed in the form of linear matrix inequalities(LMIs) to show the positively invariant property of the domain of attraction(DOA). Moreover, some sufficient conditions of controller synthesis are provided to enlarge the volume of the DOA and obtain the control gain matrix. A numerical example is simulated to demonstrate the effectiveness of the theoretical analysis results. 展开更多
关键词 Input saturation linear matrix inequalities(LMIs) multi-agent systems(MASs) self-triggered control
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State-dependent event-triggered control of multi-agent systems 被引量:1
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作者 齐斌 崔宝同 楼旭阳 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第11期215-222,共8页
Event-triggered control has been recent/y proposed as an effective strategy for the consensus of multi-agent systems. We present an improved distributed event-triggered control scheme that remedies a shortcoming of so... Event-triggered control has been recent/y proposed as an effective strategy for the consensus of multi-agent systems. We present an improved distributed event-triggered control scheme that remedies a shortcoming of some previous event- triggered control schemes in the literature. This improved distributed event-triggered method has no need for continuously monitoring each agent' neighbors. Moreover, each agent in the multi-agent systems will not exhibit the Zeno behavior. Numerical simulation results show the effectiveness of the proposed consensus control. 展开更多
关键词 distributed event-triggered control CONSENSUS RENDEZVOUS multi-agent systems
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Decentralized Event-Triggered Average Consensus for Multi-Agent Systems in CPSs with Communication Constraints 被引量:7
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作者 Zhaoxia Wang Minrui Fei +1 位作者 Dajun Du Min Zheng 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI 2015年第3期248-257,共10页
The paper investigates decentralized event-triggered average consensus problem for multi-agent systems in cyberphysical systems (CPSs) with communication constraints. To reduce communication burden and improve the com... The paper investigates decentralized event-triggered average consensus problem for multi-agent systems in cyberphysical systems (CPSs) with communication constraints. To reduce communication burden and improve the communication efficiency of multi-agent systems in CPSs, event-trigger is distributed at subsystem/agent level. A multi-agent system is then modeled as a reduced dimension hybrid system by taking into account decentralized event-triggered mechanism, communication delays and data dropouts within one framework. Some sufficient conditions for average consensus of each agent and an upper bound of communication delay and maximal allowable number of successive data dropouts (MANSD) are obtained, which can conveniently provide the relationship between the triggering parameters, communication constraints and the system stability. Specially, the quantitative relationship between the triggering parameters, MANSD and the system stability is derived. Finally, simulation results are given to illustrate the effectiveness of the proposed method. © 2014 Chinese Association of Automation. 展开更多
关键词 Embedded systems Hybrid systems system stability
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Testing of Lightning Protective System of a Residential Structure: Comparison of Data Obtained in Rocket-triggered Lightning and Current Surge Generator Experiments
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作者 G. Maslowski V.A. Rakov +9 位作者 S. Wyderka J. Bajorek B.A. DeCarlo J. Jerauld G.H. Schnetzer J. Schoene M.A. Uman K.J. Rambo D.M. Jordan W. Krata 《高电压技术》 EI CAS CSCD 北大核心 2008年第12期2575-2582,共8页
We present a comparison of data obtained during testing of lightning protective system of a residential structure in rocket-triggered lightning experiment at the International Center for Lightning Research and Testing... We present a comparison of data obtained during testing of lightning protective system of a residential structure in rocket-triggered lightning experiment at the International Center for Lightning Research and Testing(ICLRT)at Camp Blanding,Florida,and current surge generator experiment at Rzeszow University of Technology in Poland.Three different configurations of LPS were tested in Poland with the dc grounding resistances of the entire system 4.09 Ω(LPS 1a),1.65 Ω(LPS 1b),and 2.88 Ω(LPS 2).For LPS 1a with three ground rods the value of the peak current entering the electrical circuit neutral was about 56% of the injected current peak,and for LPS 1b with two additional ground rods and two 5 m long buried horizontal conductors it was about 16%.For LPS 2 with five ground rods interconnected by a buried loop conductor this ratio was 21%.The current waveshapes in the ground rods differed from the injected current waveshapes and the current waveshapes in other parts of the test system,especially,for poorer-grounding LPS 1a.The surge-generator results are consistent with those of triggered-lightning experiments at Camp Blanding,Florida(DeCarlo et al.,2008 [2]). 展开更多
关键词 居民区 雷电保护系统 试验 电流冲击发生器
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Role of triggering receptor expressed on myeloid cells 1/2 in secondary injury after cerebral hemorrhage
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作者 Fan Yi Hao Wu Hai-Kang Zhao 《World Journal of Clinical Cases》 SCIE 2025年第9期1-12,共12页
Intracerebral hemorrhage(ICH)is a common severe emergency in neurosurgery,causing tremendous economic pressure on families and society and devastating effects on patients both physically and psychologically,especially... Intracerebral hemorrhage(ICH)is a common severe emergency in neurosurgery,causing tremendous economic pressure on families and society and devastating effects on patients both physically and psychologically,especially among patients with poor functional outcomes.ICH is often accompanied by decreased consciousness and limb dysfunction.This seriously affects patients’ability to live independently.Although rapid advances in neurosurgery have greatly improved patient survival,there remains insufficient evidence that surgical treatment significantly improves long-term outcomes.With in-depth pathophysiological studies after ICH,increasing evidence has shown that secondary injury after ICH is related to long-term prognosis and that the key to secondary injury is various immune-mediated neuroinflammatory reactions after ICH.In basic and clinical studies of various systemic inflammatory diseases,triggering receptor expressed on myeloid cells 1/2(TREM-1/2),and the TREM receptor family is closely related to the inflammatory response.Various inflammatory diseases can be upregulated and downregulated through receptor intervention.How the TREM receptor functions after ICH,the types of results from intervention,and whether the outcomes can improve secondary brain injury and the long-term prognosis of patients are unknown.An analysis of relevant research results from basic and clinical trials revealed that the inhibition of TREM-1 and the activation of TREM-2 can alleviate the neuroinflammatory immune response,significantly improve the long-term prognosis of neurological function in patients with cerebral hemorrhage,and thus improve the ability of patients to live independently. 展开更多
关键词 Cerebral hemorrhage Secondary injury triggering receptor expressed on myeloid cells 1/2 NEUROSURGERY Inflammatory response
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