Guan River Estuary and adjacent coastal area(GREC) suffer from serious pollution and eutrophicational problems over the recent years.Thus,reducing the land-based load through the national pollutant total load control ...Guan River Estuary and adjacent coastal area(GREC) suffer from serious pollution and eutrophicational problems over the recent years.Thus,reducing the land-based load through the national pollutant total load control program and developing hydrodynamic and water quality models that can simulate the complex circulation and water quality kinetics within the system,including longitudinal and lateral variations in nutrient and COD concentrations,is a matter of urgency.In this study,a three-dimensional,hydrodynamic,water quality model was developed in GREC,Northern Jiangsu Province.The complex three-dimensional hydrodynamics of GREC were modeled using the unstructured-grid,finite-volume,free-surface,primitive equation coastal ocean circulation model(FVCOM).The water quality model was adapted from the mesocosm nutrients dynamic model in the south Yellow Sea and considers eight compartments:dissolved inorganic nitrogen,soluble reactive phosphorus(SRP),phytoplankton,zooplankton,detritus,dissolved organic nitrogen(DON),dissolved organic phosphorus(DOP),and chemical oxygen demand.The hydrodynamic and water quality models were calibrated and confirmed for 2012 and 2013.A comparison of the model simulations with extensive dataset shows that the models accurately simulate the longitudinal distribution of the hydrodynamics and water quality.The model can be used for total load control management to improve water quality in this area.展开更多
Wave shapes that induce velocity skewness and acceleration asymmetry are usually responsible for onshore sediment transport, whereas undertow and bottom slope effect normally contribute to offshore sediment transport....Wave shapes that induce velocity skewness and acceleration asymmetry are usually responsible for onshore sediment transport, whereas undertow and bottom slope effect normally contribute to offshore sediment transport. By incorporating these counteracting driving forces in a phase-averaged manner, the theoretically-based quasi-steady formula of Wang （2007） is modified to predict the magnitude and direction of net cross-shore total load transport under the coaction of wave and current. The predictions show an excellent agreement with the measurement data on medium and fine sand collected by Dohmen-Janssen and Hanes （2002） and Schretlen （2012） in a full-scale wave flume at the Coastal Research Centre in Hannover, Germany. The modified formula can predict the net onshore transport of fine sand in sheet flows. In particular, it can predict the net offshore transport of medium sand in rippled beds through enlarged bed roughness, as well as the net offshore transport of fine-to-coarse sand in sheet flows with the aid of a new criterion to judge the occurrence of net offshore transport.展开更多
Rock-soil interface mixed ground(RSI)is often encountered in tunnel construction.The excavation loads of tunnel boring machines(TBMs)are controlled by the interaction characteristics between TBM and rock/soil layers.T...Rock-soil interface mixed ground(RSI)is often encountered in tunnel construction.The excavation loads of tunnel boring machines(TBMs)are controlled by the interaction characteristics between TBM and rock/soil layers.The different properties of rock and soil cause the varying interaction range and stress distribution.Currently,there have been several studies available to estimate excavation loads under RSI,and the conclusion is that the total loads increase with increasing the rock layer proportion in the excavation face.However,the previous studies cannot take the difference of rock/soil properties into account,except for the calculation of cutters loads.Therefore,the interaction characteristics between RSI and TBM is unclear.This paper analyzes the interaction characteristics between TBM’s main components and complex geological conditions(e.g.,layered soil,layered rock,and RSI condition).A model is proposed to calculate the total thrust and total torque assuming quasi-static equilibrium of the tunneling equipment.The rationality and applicability of the model are discussed and verified by two typical projects.Furthermore,the geological adaptability is discussed in terms of the excavation difficulty and the matching relationship between total torque and total thrust.The results indicate that when the rock layer proportion in the excavation face increases,the reduction of overall extrusion and friction loads is 1.5 times higher than the increase of disc cutters breaking load.The total loads and the ratio of the total torque to total thrust decrease approximately linearly.There is a power function relationship between the excavation difficulty index and the penetration depth.The results of this study provide an important reference for the total loads design of equipment propulsion systems and the parameter adjustment during tunnel construction.展开更多
It is important to have a reasonable estimation of sediment transport rate with respect to its significant role in the planning and management of water resources projects. The complicate nature of sediment transport i...It is important to have a reasonable estimation of sediment transport rate with respect to its significant role in the planning and management of water resources projects. The complicate nature of sediment transport in gravel-bed rivers causes inaccuracies of empirical formulas in the prediction of this phenomenon. Artificial intelligences as alternative approaches can provide solutions to such complex problems. The present study aimed at investigating the capability of kernel-based approaches in predicting total sediment loads and identification of influential parameters of total sediment transport. For this purpose, Gaussian process regression(GPR), Support vector machine(SVM) and kernel extreme learning machine(KELM) are applied to enhance the prediction level of total sediment loads in 19 mountain gravel-bed streams and rivers located in the United States. Several parameters based on two scenarios are investigated and consecutive predicted results are compared with some well-known formulas. Scenario 1 considers only hydraulic characteristics and on the other side, the second scenario was formed using hydraulic and sediment properties. The obtained results reveal that using the parameters of hydraulic conditions asinputs gives a good estimation of total sediment loads. Furthermore, it was revealed that KELM method with input parameters of Froude number(Fr), ratio of average velocity(V) to shear velocity(U*) and shields number(θ) yields a correlation coefficient(R) of 0.951, a Nash-Sutcliffe efficiency(NSE) of 0.903 and root mean squared error(RMSE) of 0.021 and indicates superior results compared with other methods. Performing sensitivity analysis showed that the ratio of average velocity to shear flow velocity and the Froude number are the most effective parameters in predicting total sediment loads of gravel-bed rivers.展开更多
Total pollutant load control management for total dissolved nitrogen(TDN) is an urgent task required to gain a good water quality status in Jiaozhou Bay(JZB), China. In this paper, the stoichiometry of multiform TDN o...Total pollutant load control management for total dissolved nitrogen(TDN) is an urgent task required to gain a good water quality status in Jiaozhou Bay(JZB), China. In this paper, the stoichiometry of multiform TDN on land-ocean interactions associated with marine biogeochemical reaction(LOIMBR) was studied by modeling the load-response relationship based on a three-dimensional water quality model of nitrogen in JZB. The results showed that the stoichiometry on LOIMBR of dissolved organic nitrogen(DON), NO3-N and NH4-N was 3:1:1, with one-third of the contribution on the concentration of dissolved inorganic nitrogen(DIN) in JZB for the land-based DON loads to DIN loads. Based on the stoichiometric relationship of nitrogen forms, the total maximum allocated load(TMAL) of equivalent TDN(ETDN) was approximately 5300 t a^-1 in JZB, equivalent to the TMAL of 5700, 5800 and 15600 t a^-1 for NH4-N, NO3-N and DON, respectively. According to the loads of ETDN, there were four outfalls overloaded in JZB in 2015, which lie in the head of the bay. In the four overloaded outfalls, besides NO3-N, NH4-N was the critical nitrogen control form for Moshui River, while DON for Dagu River and Haibo River. The results of numerical experiments further showed that JZB will achieve good water quality after 7 years by implementation of the 'different emission reduction' based on TMAL of ETDN, which is significantly better than 'equal percent removal'.展开更多
Bone cement has the capacity to release antibiotic molecules if any antibiotic is included in it, and these elution properties are improved as cement porosity is increased. In vitro studies have shown high local antib...Bone cement has the capacity to release antibiotic molecules if any antibiotic is included in it, and these elution properties are improved as cement porosity is increased. In vitro studies have shown high local antibiotic concentration for many hours or few days after its use. Antibiotic loaded bone cement(ALBC) is helpful when treating an infection in total knee arthroplasty(TKA) revision surgery. The purpose of this paper was to review the evidence for the routine use of ALBC in TKA in the literature, its pros and cons. Many authors have recommended the use of ALBC also in primary TKA for infection prophylaxis, but the evidence based on data from National Registries, randomized clinical trials and meta-analysis suggest a protective effect of ALBC against infection when used in hips, but not(or only mild) in knees. A possible explanation to this finding is that the duration and quantity of locally elevated antibiotic levels after surgery are smaller in TKA, due to the smaller amount of cement used for fixation in TKA-only a layer in the bone surface. There are some concerns about the routine use of ALBC in primary TKA as prophylaxis against infection: Firstly, there is a risk of hypersensivity or toxicity even when the chance is highly improbable. Secondly, there is a reduction in the mechanical properties of the cement, but this can be probably neglected if the antibiotic is used in low doses, not more than 1 g per 40 g cement package. Another significant concern is the increased economic cost, which could be overlooked if there were enough savings in treating fewer prosthetic infections. Finally, there is also a risk of selection of antibiotic-resistant strains of bacteria and this could be the main concern. If used, the choice of the antibiotic mixed in ALBC should consider microbiological aspects(broad antimicrobial spectrum and low rate of resistant bacteria), physical and chemical aspects(thermal stability, high water solubility), pharmacological characteristics(low risk to allergic reactions or toxicity) and economic aspects(not too expensive). The most commonly used antibiotics in ALBC are gentamicin, tobramycin and vancomycin. In conclusion, there is a paucity of randomized clinical trials in the use of ALBC in primary TKAs and the actual evidence of the effect of ALBC in reducing the risk of infection is insufficient. This, in addition to concerns about patient safety, risks of increase in the antibiotic resistance of microorganisms and the increase in costs in the procedure, lead us to recommend a cautious use of ALBC, perhaps only in high-risk patients(immunocompromised, morbidly obese, diabetic and patients with previous history of fracture or infection around the knee) unless the benefits of ALBC use were fully proven. Meanwhile, the rigorous use of peri-operative prophylactic systemic antibiotics and adoption of efficient antiseptic procedures and improved surgical techniques must be considered the gold standard in infection prevention in TKA surgery.展开更多
This study aims to provide a quantitative basis for the precision emission reduction of land-based total nitrogen(TN)pollutants in Laizhou Bay(LZB),China.The total maximum allocated load(TMAL)of TN pollutants within j...This study aims to provide a quantitative basis for the precision emission reduction of land-based total nitrogen(TN)pollutants in Laizhou Bay(LZB),China.The total maximum allocated load(TMAL)of TN pollutants within jurisdictions around LZB was calculated using the stepwise simulation-optimization model after the division of source units,simulation of the concentration response matrix,setting of the additional constraint conditions for stepwise source units,and calculation of TMAL.The load reduction allocation system for jurisdictions can be constructed on the basis of the TMAL and the load monitored or statistics.The index system for TN emission reduction included indices for two groups:a fixed index of marine emission reduction rate for jurisdictions,which was 11.93%on average;and threshold indices of pollution prevention rate at sources,the increment rate of pollution removal by municipal sewage treatment systems,and watershed retention of jurisdictions,which were 7.43%,1.58%,and 1.09%on average,respectively.Efficiency of pollutant reduction can be evaluated using a 3D hydrodynamic-water quality model.Simulation results showed that the precise reduction indicators achieved the seawater quality improvement target of LZB 5 years earlier than the equal proportion reduction indicators currently used in LZB Basin.展开更多
Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the probl...Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the problem of the lack of consideration of adhesion difference of train wheelsets in the existing high-speed train electric-air braking force optimal allocation strategies.In this method,the braking strategy gives priority to the use of electric braking force.The force model of a single train in the braking process is analyzed to calculate the change of adhesion between the wheel and rail of each wheelset after axle load transfer,and then the adhesion of the train is estimated in real time.Next,with the goal of maximizing the total adhesion utilization ratio of trailer/motor vehicles,a linear programming distribution function is constructed.The proportional coefficient of adhesion utilization ratio of each train and the application upper limit of braking force in the function is updated according to the change time point of wheelset adhesion.Finally,the braking force is dynamically allocated.The simulation results of Matlab/Simulink show that the proposed algorithm not only uses the different adhesion limits of each trailer to reduce the total amount of braking force undertaken by the motor vehicle,but also considers the adhesion difference of each wheelset.The strategy can effectively reduce the risk and time of motor vehicles during the braking process and improve the stability of the train braking.展开更多
Phosphorus and nitrogen are essential nutrients for living organisms. Their concentration in the water of an aquatic ecosystem is one of the factors responsible for the trophic status of the lake and is related to the...Phosphorus and nitrogen are essential nutrients for living organisms. Their concentration in the water of an aquatic ecosystem is one of the factors responsible for the trophic status of the lake and is related to the soils of the region and to the human activities carried out in their basins. These nutrients are also found in the bottom sediments, where they can either be retained or re-enter the water column. Since the information about the concentrations of nutrients in the water of some lakes of La Pampa (Argentina) is fragmentary, the aim of this study is to describe the trophic status of some shallow lakes of the semiarid center of Argentina and analyze its relation with the human activities in their basins, the concentrations of nutrients and organic matter and particle size distribution of sediments. To this end, we studied ten shallow lakes subjected to different anthropogenic influences (agriculture, agriculture and livestock and impacted by cities). All were hypertrophic and the concentrations of total phosphorus and total nitrogen were among the highest reported globally. Since some lakes had no fish, cladoceran grazing (top-down effect) led them have reduced concentrations of phytoplankton chlorophyll-a and high water transparency. This relativizes the use of these parameters to determine the trophic status. The sediments of seven of the studied lakes were predominated by fine sands, whereas three were predominated by silts. Nutrient and organic matter content were high, with higher concentrations in lakes with prevalence of fine particles. The reduced adsorption capacity of sediments, the resuspension by wind, the anthropogenic input and the accumulation favored by the arheic character of the basins would explain the high concentrations of nutrients in the water of these Pampean environments.展开更多
Pomegranate peels were studied for the effect of gamma irradiation on microbial decontamination along with its effect on total phenolic content and in vitro antioxidant activity. Gamma irradiation was applied at vario...Pomegranate peels were studied for the effect of gamma irradiation on microbial decontamination along with its effect on total phenolic content and in vitro antioxidant activity. Gamma irradiation was applied at various dose levels (5.0, 10.0, 15.0 and 25.0 kGy) on pomegranate peel powder. Both the values of total phenolic content and in vitro antioxi- dant activity were positively correlated and showed a significant increase (p < 0.05) for 10.0 kGy irradiated dose level immediately after irradiation and 60 days of post irradiation storage. At 5.0 kGy and above dose level, gamma irradia- tion has reduced microbial count of pomegranate peel powder to nil. Post irradiation storage studies also showed that, the irradiated peel powder was microbiologically safe even after 90 days of storage period.展开更多
For pollution research with regard to urban surface runoff, most sampling strategies to date have focused on differences in land usage. With single land-use sampling, total surface runoff pollution effect cannot be ev...For pollution research with regard to urban surface runoff, most sampling strategies to date have focused on differences in land usage. With single land-use sampling, total surface runoff pollution effect cannot be evaluated unless every land usage spot is monitored. Through a new sampling strategy known as mixed stormwater sampling for a street community at discharge outlet adjacent to river, this study assessed the total urban surface runoff pollution effect caused by a variety of land uses and the pollutants washed off from the rain pipe system in the Futian River watershed in Shenzhen City of China. The water quality monitoring indices were COD （chemical oxygen demand）, TSS （total suspend solid）, TP （total phosphorus）, TN （total nitrogen） and BOD （biochemical oxygen demand）. The sums of total pollution loads discharged into the river for the four indices of COD, TSS, TN, and TP over all seven rainfall events were very different. The mathematical model for simulating total pollution loads was established from discharge outlet mixed stormwater sampling of total pollution loads on the basis of four parameters： rainfall intensity, total land area, impervious land area, and pervious land area. In order to treat surface runoff pollution, the values of MFF30 （mass first flush ratio） and FF30 （first 30% of runoff volume） can be considered as split-flow control criteria to obtain more effective and economical design of structural BMPs （best management practices） facilities.展开更多
目的探讨脑小血管病(cerebral small vessel disease,CSVD)患者的血清尿酸(uric acid,UA)水平与步态运动学特征间关系。方法回顾性分析2023年1月至2023年12月就诊于广州中医药大学附属中山中医院神经内科·康复科且诊断为CSVD的患...目的探讨脑小血管病(cerebral small vessel disease,CSVD)患者的血清尿酸(uric acid,UA)水平与步态运动学特征间关系。方法回顾性分析2023年1月至2023年12月就诊于广州中医药大学附属中山中医院神经内科·康复科且诊断为CSVD的患者。收集一般资料,对患者进行三维步态分析,结合步态结果将患者分为轻度步态障碍组(0~1分)、中度步态障碍组(2~3分)和重度步态功能障碍组(4~5分),记录CSVD影像总负荷及UA等血清学结果。分析UA水平与CSVD步态障碍之间的关系。结果本研究纳入CSVD患者共105例,根据步态障碍严重程度分组,轻度步态障碍组40例,中度步态障碍组49例,重度步态障碍组16例。中度步态障碍组的血清UA[(358.43±13.44)μmol/L]高于轻度步态障碍组血清UA[(336.00±12.48)μmol/L],重度步态障碍组的血清UA[(289.94±11.88)μmol/L]低于轻、中度步态障碍组(P<0.05),重度步态障碍组的蒙特利尔认知评估量表评分(21.38±0.13)低于轻、中度步态障碍组(28.05±0.09;25.22±0.10)(P<0.05);CSVD影像学总负荷重度组的步宽[(13.26±2.80)cm]相比轻、中度组[(11.22±1.70)cm vs.(11.65±2.70)cm]增加(P<0.05),CSVD影像学总负荷重度组左侧摆动相(35.90%)相比轻、中度组(38.50%vs.37.20%)下降(P<0.05);Spearman相关分析显示血清UA水平与脑微出血呈负相关(r=-0.20,P=0.04),高尿酸血症与脑萎缩呈负相关(r=-0.20,P=0.04);在轻中度步态障碍组患者中,高尿酸血症与步态障碍总负荷之间呈正相关(r=0.25,P=0.02),高尿酸血症与右侧步速(r=-0.22,P=0.04)、右侧步幅(r=-0.29,P<0.01)、左侧步速(r=-0.32,P<0.01)、左侧步频(r=-0.29,P<0.01)、左侧步幅(r=-0.26,P=0.01)均呈负相关。结论CSVD轻中度步态障碍患者中,UA水平及高尿酸血症的发生与步态障碍总负荷呈正相关,步态障碍以双侧步速、双侧步幅、左侧步频减少为主要特征。展开更多
基金supported by Natural Science Foundation of China-Shandong Joint Fund for Marine Science Research Centers (Grant No.U1406403)the Sea Area Use Fund of Jiangsu Province (Environmental Capacity for the Key Coast of Jiangsu Province)+1 种基金the National Natural Science Foundation of China (No.41340046)Modeling work was completed at the Computing Services Center,Ocean University of China
文摘Guan River Estuary and adjacent coastal area(GREC) suffer from serious pollution and eutrophicational problems over the recent years.Thus,reducing the land-based load through the national pollutant total load control program and developing hydrodynamic and water quality models that can simulate the complex circulation and water quality kinetics within the system,including longitudinal and lateral variations in nutrient and COD concentrations,is a matter of urgency.In this study,a three-dimensional,hydrodynamic,water quality model was developed in GREC,Northern Jiangsu Province.The complex three-dimensional hydrodynamics of GREC were modeled using the unstructured-grid,finite-volume,free-surface,primitive equation coastal ocean circulation model(FVCOM).The water quality model was adapted from the mesocosm nutrients dynamic model in the south Yellow Sea and considers eight compartments:dissolved inorganic nitrogen,soluble reactive phosphorus(SRP),phytoplankton,zooplankton,detritus,dissolved organic nitrogen(DON),dissolved organic phosphorus(DOP),and chemical oxygen demand.The hydrodynamic and water quality models were calibrated and confirmed for 2012 and 2013.A comparison of the model simulations with extensive dataset shows that the models accurately simulate the longitudinal distribution of the hydrodynamics and water quality.The model can be used for total load control management to improve water quality in this area.
基金supported by the National Natural Science Foundation of China(Grant No.51179211)
文摘Wave shapes that induce velocity skewness and acceleration asymmetry are usually responsible for onshore sediment transport, whereas undertow and bottom slope effect normally contribute to offshore sediment transport. By incorporating these counteracting driving forces in a phase-averaged manner, the theoretically-based quasi-steady formula of Wang （2007） is modified to predict the magnitude and direction of net cross-shore total load transport under the coaction of wave and current. The predictions show an excellent agreement with the measurement data on medium and fine sand collected by Dohmen-Janssen and Hanes （2002） and Schretlen （2012） in a full-scale wave flume at the Coastal Research Centre in Hannover, Germany. The modified formula can predict the net onshore transport of fine sand in sheet flows. In particular, it can predict the net offshore transport of medium sand in rippled beds through enlarged bed roughness, as well as the net offshore transport of fine-to-coarse sand in sheet flows with the aid of a new criterion to judge the occurrence of net offshore transport.
基金funded by National Key R&D Program of China[No.2018YFB1702505]National Natural Science Foundation of China[Grant Nos.12022205 and 11872269].
文摘Rock-soil interface mixed ground(RSI)is often encountered in tunnel construction.The excavation loads of tunnel boring machines(TBMs)are controlled by the interaction characteristics between TBM and rock/soil layers.The different properties of rock and soil cause the varying interaction range and stress distribution.Currently,there have been several studies available to estimate excavation loads under RSI,and the conclusion is that the total loads increase with increasing the rock layer proportion in the excavation face.However,the previous studies cannot take the difference of rock/soil properties into account,except for the calculation of cutters loads.Therefore,the interaction characteristics between RSI and TBM is unclear.This paper analyzes the interaction characteristics between TBM’s main components and complex geological conditions(e.g.,layered soil,layered rock,and RSI condition).A model is proposed to calculate the total thrust and total torque assuming quasi-static equilibrium of the tunneling equipment.The rationality and applicability of the model are discussed and verified by two typical projects.Furthermore,the geological adaptability is discussed in terms of the excavation difficulty and the matching relationship between total torque and total thrust.The results indicate that when the rock layer proportion in the excavation face increases,the reduction of overall extrusion and friction loads is 1.5 times higher than the increase of disc cutters breaking load.The total loads and the ratio of the total torque to total thrust decrease approximately linearly.There is a power function relationship between the excavation difficulty index and the penetration depth.The results of this study provide an important reference for the total loads design of equipment propulsion systems and the parameter adjustment during tunnel construction.
文摘It is important to have a reasonable estimation of sediment transport rate with respect to its significant role in the planning and management of water resources projects. The complicate nature of sediment transport in gravel-bed rivers causes inaccuracies of empirical formulas in the prediction of this phenomenon. Artificial intelligences as alternative approaches can provide solutions to such complex problems. The present study aimed at investigating the capability of kernel-based approaches in predicting total sediment loads and identification of influential parameters of total sediment transport. For this purpose, Gaussian process regression(GPR), Support vector machine(SVM) and kernel extreme learning machine(KELM) are applied to enhance the prediction level of total sediment loads in 19 mountain gravel-bed streams and rivers located in the United States. Several parameters based on two scenarios are investigated and consecutive predicted results are compared with some well-known formulas. Scenario 1 considers only hydraulic characteristics and on the other side, the second scenario was formed using hydraulic and sediment properties. The obtained results reveal that using the parameters of hydraulic conditions asinputs gives a good estimation of total sediment loads. Furthermore, it was revealed that KELM method with input parameters of Froude number(Fr), ratio of average velocity(V) to shear velocity(U*) and shields number(θ) yields a correlation coefficient(R) of 0.951, a Nash-Sutcliffe efficiency(NSE) of 0.903 and root mean squared error(RMSE) of 0.021 and indicates superior results compared with other methods. Performing sensitivity analysis showed that the ratio of average velocity to shear flow velocity and the Froude number are the most effective parameters in predicting total sediment loads of gravel-bed rivers.
基金supported by the National Natural Science Foundation of China (No.41676062)the NSFC-Shandong Joint Fund for Marine Ecology and Environmental Sciences (No.U1606404)+1 种基金the Key R&D Program of Shandong (No.2018GHY115005)the NSFC-Shandong Joint Fund (No.U1706215)。
文摘Total pollutant load control management for total dissolved nitrogen(TDN) is an urgent task required to gain a good water quality status in Jiaozhou Bay(JZB), China. In this paper, the stoichiometry of multiform TDN on land-ocean interactions associated with marine biogeochemical reaction(LOIMBR) was studied by modeling the load-response relationship based on a three-dimensional water quality model of nitrogen in JZB. The results showed that the stoichiometry on LOIMBR of dissolved organic nitrogen(DON), NO3-N and NH4-N was 3:1:1, with one-third of the contribution on the concentration of dissolved inorganic nitrogen(DIN) in JZB for the land-based DON loads to DIN loads. Based on the stoichiometric relationship of nitrogen forms, the total maximum allocated load(TMAL) of equivalent TDN(ETDN) was approximately 5300 t a^-1 in JZB, equivalent to the TMAL of 5700, 5800 and 15600 t a^-1 for NH4-N, NO3-N and DON, respectively. According to the loads of ETDN, there were four outfalls overloaded in JZB in 2015, which lie in the head of the bay. In the four overloaded outfalls, besides NO3-N, NH4-N was the critical nitrogen control form for Moshui River, while DON for Dagu River and Haibo River. The results of numerical experiments further showed that JZB will achieve good water quality after 7 years by implementation of the 'different emission reduction' based on TMAL of ETDN, which is significantly better than 'equal percent removal'.
文摘Bone cement has the capacity to release antibiotic molecules if any antibiotic is included in it, and these elution properties are improved as cement porosity is increased. In vitro studies have shown high local antibiotic concentration for many hours or few days after its use. Antibiotic loaded bone cement(ALBC) is helpful when treating an infection in total knee arthroplasty(TKA) revision surgery. The purpose of this paper was to review the evidence for the routine use of ALBC in TKA in the literature, its pros and cons. Many authors have recommended the use of ALBC also in primary TKA for infection prophylaxis, but the evidence based on data from National Registries, randomized clinical trials and meta-analysis suggest a protective effect of ALBC against infection when used in hips, but not(or only mild) in knees. A possible explanation to this finding is that the duration and quantity of locally elevated antibiotic levels after surgery are smaller in TKA, due to the smaller amount of cement used for fixation in TKA-only a layer in the bone surface. There are some concerns about the routine use of ALBC in primary TKA as prophylaxis against infection: Firstly, there is a risk of hypersensivity or toxicity even when the chance is highly improbable. Secondly, there is a reduction in the mechanical properties of the cement, but this can be probably neglected if the antibiotic is used in low doses, not more than 1 g per 40 g cement package. Another significant concern is the increased economic cost, which could be overlooked if there were enough savings in treating fewer prosthetic infections. Finally, there is also a risk of selection of antibiotic-resistant strains of bacteria and this could be the main concern. If used, the choice of the antibiotic mixed in ALBC should consider microbiological aspects(broad antimicrobial spectrum and low rate of resistant bacteria), physical and chemical aspects(thermal stability, high water solubility), pharmacological characteristics(low risk to allergic reactions or toxicity) and economic aspects(not too expensive). The most commonly used antibiotics in ALBC are gentamicin, tobramycin and vancomycin. In conclusion, there is a paucity of randomized clinical trials in the use of ALBC in primary TKAs and the actual evidence of the effect of ALBC in reducing the risk of infection is insufficient. This, in addition to concerns about patient safety, risks of increase in the antibiotic resistance of microorganisms and the increase in costs in the procedure, lead us to recommend a cautious use of ALBC, perhaps only in high-risk patients(immunocompromised, morbidly obese, diabetic and patients with previous history of fracture or infection around the knee) unless the benefits of ALBC use were fully proven. Meanwhile, the rigorous use of peri-operative prophylactic systemic antibiotics and adoption of efficient antiseptic procedures and improved surgical techniques must be considered the gold standard in infection prevention in TKA surgery.
基金the fund provided by the Basic Scientific Research Funds of Dalian University of Technology(No.DUT21RC(3)035)the Open Funds of Key Laboratory of Estuarine and Coastal Environment(No.HKHA2022001)。
文摘This study aims to provide a quantitative basis for the precision emission reduction of land-based total nitrogen(TN)pollutants in Laizhou Bay(LZB),China.The total maximum allocated load(TMAL)of TN pollutants within jurisdictions around LZB was calculated using the stepwise simulation-optimization model after the division of source units,simulation of the concentration response matrix,setting of the additional constraint conditions for stepwise source units,and calculation of TMAL.The load reduction allocation system for jurisdictions can be constructed on the basis of the TMAL and the load monitored or statistics.The index system for TN emission reduction included indices for two groups:a fixed index of marine emission reduction rate for jurisdictions,which was 11.93%on average;and threshold indices of pollution prevention rate at sources,the increment rate of pollution removal by municipal sewage treatment systems,and watershed retention of jurisdictions,which were 7.43%,1.58%,and 1.09%on average,respectively.Efficiency of pollutant reduction can be evaluated using a 3D hydrodynamic-water quality model.Simulation results showed that the precise reduction indicators achieved the seawater quality improvement target of LZB 5 years earlier than the equal proportion reduction indicators currently used in LZB Basin.
基金supported by the National Natural Science Foundation of China(Grant Nos.62173137,52172403,62303178).
文摘Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the problem of the lack of consideration of adhesion difference of train wheelsets in the existing high-speed train electric-air braking force optimal allocation strategies.In this method,the braking strategy gives priority to the use of electric braking force.The force model of a single train in the braking process is analyzed to calculate the change of adhesion between the wheel and rail of each wheelset after axle load transfer,and then the adhesion of the train is estimated in real time.Next,with the goal of maximizing the total adhesion utilization ratio of trailer/motor vehicles,a linear programming distribution function is constructed.The proportional coefficient of adhesion utilization ratio of each train and the application upper limit of braking force in the function is updated according to the change time point of wheelset adhesion.Finally,the braking force is dynamically allocated.The simulation results of Matlab/Simulink show that the proposed algorithm not only uses the different adhesion limits of each trailer to reduce the total amount of braking force undertaken by the motor vehicle,but also considers the adhesion difference of each wheelset.The strategy can effectively reduce the risk and time of motor vehicles during the braking process and improve the stability of the train braking.
文摘Phosphorus and nitrogen are essential nutrients for living organisms. Their concentration in the water of an aquatic ecosystem is one of the factors responsible for the trophic status of the lake and is related to the soils of the region and to the human activities carried out in their basins. These nutrients are also found in the bottom sediments, where they can either be retained or re-enter the water column. Since the information about the concentrations of nutrients in the water of some lakes of La Pampa (Argentina) is fragmentary, the aim of this study is to describe the trophic status of some shallow lakes of the semiarid center of Argentina and analyze its relation with the human activities in their basins, the concentrations of nutrients and organic matter and particle size distribution of sediments. To this end, we studied ten shallow lakes subjected to different anthropogenic influences (agriculture, agriculture and livestock and impacted by cities). All were hypertrophic and the concentrations of total phosphorus and total nitrogen were among the highest reported globally. Since some lakes had no fish, cladoceran grazing (top-down effect) led them have reduced concentrations of phytoplankton chlorophyll-a and high water transparency. This relativizes the use of these parameters to determine the trophic status. The sediments of seven of the studied lakes were predominated by fine sands, whereas three were predominated by silts. Nutrient and organic matter content were high, with higher concentrations in lakes with prevalence of fine particles. The reduced adsorption capacity of sediments, the resuspension by wind, the anthropogenic input and the accumulation favored by the arheic character of the basins would explain the high concentrations of nutrients in the water of these Pampean environments.
文摘Pomegranate peels were studied for the effect of gamma irradiation on microbial decontamination along with its effect on total phenolic content and in vitro antioxidant activity. Gamma irradiation was applied at various dose levels (5.0, 10.0, 15.0 and 25.0 kGy) on pomegranate peel powder. Both the values of total phenolic content and in vitro antioxi- dant activity were positively correlated and showed a significant increase (p < 0.05) for 10.0 kGy irradiated dose level immediately after irradiation and 60 days of post irradiation storage. At 5.0 kGy and above dose level, gamma irradia- tion has reduced microbial count of pomegranate peel powder to nil. Post irradiation storage studies also showed that, the irradiated peel powder was microbiologically safe even after 90 days of storage period.
基金supported by the Key Project of Chinese Ministry of Education(No.108177)the National Natural Science Foundation of China(No.50679049)
文摘For pollution research with regard to urban surface runoff, most sampling strategies to date have focused on differences in land usage. With single land-use sampling, total surface runoff pollution effect cannot be evaluated unless every land usage spot is monitored. Through a new sampling strategy known as mixed stormwater sampling for a street community at discharge outlet adjacent to river, this study assessed the total urban surface runoff pollution effect caused by a variety of land uses and the pollutants washed off from the rain pipe system in the Futian River watershed in Shenzhen City of China. The water quality monitoring indices were COD （chemical oxygen demand）, TSS （total suspend solid）, TP （total phosphorus）, TN （total nitrogen） and BOD （biochemical oxygen demand）. The sums of total pollution loads discharged into the river for the four indices of COD, TSS, TN, and TP over all seven rainfall events were very different. The mathematical model for simulating total pollution loads was established from discharge outlet mixed stormwater sampling of total pollution loads on the basis of four parameters： rainfall intensity, total land area, impervious land area, and pervious land area. In order to treat surface runoff pollution, the values of MFF30 （mass first flush ratio） and FF30 （first 30% of runoff volume） can be considered as split-flow control criteria to obtain more effective and economical design of structural BMPs （best management practices） facilities.
