This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a ...This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a current dipole and volume currents. Then by using the simulated magnetic fields based on torso-heart model as input, the cardiac current sources--an array of current dipoles by optimal constrained linear inverse method are constructed. Next, the current dipole array reconstruction considering boundaries is compared with that in an unbounded homogeneous medium. Furthermore, the influence of random noise on reconstruction is also considered and the reconstructing effect is judged by several reconstructing parameters.展开更多
It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current mult...It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares （MNLS） method, the optimal weighted pseudoinverse method （OWPIM）, and the optimal constrained linear inverse method （OCLIM） are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.展开更多
A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model,...A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic （ECG） and magneto-cardiogram （MCG） simulation study by using the boundary element method （BEM）. Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.展开更多
Low collateral damage weapons achieve controlled personnel injury through the coupling of shock waves and particle swarms,where the particle swarms arise from the high-explosive dispersion of compacted metal particle ...Low collateral damage weapons achieve controlled personnel injury through the coupling of shock waves and particle swarms,where the particle swarms arise from the high-explosive dispersion of compacted metal particle ring.To investigate the dynamic response of the human target under combined shock waves and particle swarms loading,a physical human surrogate torso model(HSTM)was developed,and the dynamic response test experiment was conducted under the combined loading.The effects of particle size on the loading parameters,the damage patterns of the ballistic plate and HSTM,and the dynamic response parameters of the HSTM with and without protection are mainly analyzed.Our findings revealed that particle swarms can effectively delay the shock wave attenuation,especially the best effect when the particle size was 0.28–0.45 mm.The ballistic plate mainly exhibited dense perforation of the outer fabric and impacted crater damage of ceramic plates,whereas the unprotected HSTM was mainly dominated by high-density and small-size ballistic cavity group damage.The peak values of the dynamic response parameters for the HSTM under combined loading were significantly larger than those under bare charge loading,with multiple peaks observed.Under unprotected conditions,the peak acceleration of skeletons and peak pressure of organs increased with the particle size.Under protected conditions,the particle size,the number of particles hit,and the fit of the ballistic plate to the HSTM together affected the dynamic response parameters of the HSTM.展开更多
基金Project supported by the State Key Development Program for Basic Research of China(Grant No.2006CB601007)the National Natural Science Foundation of China(Grant No.10674006)the National High Technology Research and Development Program of China(Grant No.2007AA03Z238)
文摘This paper constructs a concentric ellipsoid torso-heart model by boundary element method and investigates the impacts of model structures on the cardiac magnetic fields generated by both equivalent primary source--a current dipole and volume currents. Then by using the simulated magnetic fields based on torso-heart model as input, the cardiac current sources--an array of current dipoles by optimal constrained linear inverse method are constructed. Next, the current dipole array reconstruction considering boundaries is compared with that in an unbounded homogeneous medium. Furthermore, the influence of random noise on reconstruction is also considered and the reconstructing effect is judged by several reconstructing parameters.
基金Project supported by the State Key Development Program for Basic Research of China(Grant No.2006CB601007)the National Natural Science Foundation of China(Grant No.10674006)the National High Technology Research and Development Program of China(Grant No.2007AA03Z238)
文摘It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares （MNLS） method, the optimal weighted pseudoinverse method （OWPIM）, and the optimal constrained linear inverse method （OCLIM） are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.
基金supported by the State Key Development Program for Basic Research of China (Grant No. 2011CBA00106)the National Natural Science Foundation of China (Grant Nos. 10674006, 81171421, and 61101046)the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238)
文摘A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic （ECG） and magneto-cardiogram （MCG） simulation study by using the boundary element method （BEM）. Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.
文摘Low collateral damage weapons achieve controlled personnel injury through the coupling of shock waves and particle swarms,where the particle swarms arise from the high-explosive dispersion of compacted metal particle ring.To investigate the dynamic response of the human target under combined shock waves and particle swarms loading,a physical human surrogate torso model(HSTM)was developed,and the dynamic response test experiment was conducted under the combined loading.The effects of particle size on the loading parameters,the damage patterns of the ballistic plate and HSTM,and the dynamic response parameters of the HSTM with and without protection are mainly analyzed.Our findings revealed that particle swarms can effectively delay the shock wave attenuation,especially the best effect when the particle size was 0.28–0.45 mm.The ballistic plate mainly exhibited dense perforation of the outer fabric and impacted crater damage of ceramic plates,whereas the unprotected HSTM was mainly dominated by high-density and small-size ballistic cavity group damage.The peak values of the dynamic response parameters for the HSTM under combined loading were significantly larger than those under bare charge loading,with multiple peaks observed.Under unprotected conditions,the peak acceleration of skeletons and peak pressure of organs increased with the particle size.Under protected conditions,the particle size,the number of particles hit,and the fit of the ballistic plate to the HSTM together affected the dynamic response parameters of the HSTM.
