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Robust Recommendation Adversarial Training Based on Self-Purification Data Sanitization
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作者 Haiyan Long Gang Chen Hai Chen 《Computers, Materials & Continua》 2026年第4期840-859,共20页
The performance of deep recommendation models degrades significantly under data poisoning attacks.While adversarial training methods such as Vulnerability-Aware Training(VAT)enhance robustness by injecting perturbatio... The performance of deep recommendation models degrades significantly under data poisoning attacks.While adversarial training methods such as Vulnerability-Aware Training(VAT)enhance robustness by injecting perturbations into embeddings,they remain limited by coarse-grained noise and a static defense strategy,leaving models susceptible to adaptive attacks.This study proposes a novel framework,Self-Purification Data Sanitization(SPD),which integrates vulnerability-aware adversarial training with dynamic label correction.Specifically,SPD first identifies high-risk users through a fragility scoring mechanism,then applies self-purification by replacing suspicious interactions with model-predicted high-confidence labels during training.This closed-loop process continuously sanitizes the training data and breaks the protection ceiling of conventional adversarial training.Experiments demonstrate that SPD significantly improves the robustness of both Matrix Factorization(MF)and LightGCN models against various poisoning attacks.We show that SPD effectively suppresses malicious gradient propagation and maintains recommendation accuracy.Evaluations on Gowalla and Yelp2018 confirmthat SPD-trainedmodels withstandmultiple attack strategies—including Random,Bandwagon,DP,and Rev attacks—while preserving performance. 展开更多
关键词 ROBUSTNESS adversarial defense recommendation system poisoning attack SELF-PURIFICATION
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Personalized Recommendation System Using Deep Learning with Bayesian Personalized Ranking
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作者 Sophort Siet Sony Peng +1 位作者 Ilkhomjon Sadriddinov Kyuwon Park 《Computers, Materials & Continua》 2026年第3期1423-1443,共21页
Recommendation systems have become indispensable for providing tailored suggestions and capturing evolving user preferences based on interaction histories.The collaborative filtering(CF)model,which depends exclusively... Recommendation systems have become indispensable for providing tailored suggestions and capturing evolving user preferences based on interaction histories.The collaborative filtering(CF)model,which depends exclusively on user-item interactions,commonly encounters challenges,including the cold-start problem and an inability to effectively capture the sequential and temporal characteristics of user behavior.This paper introduces a personalized recommendation system that combines deep learning techniques with Bayesian Personalized Ranking(BPR)optimization to address these limitations.With the strong support of Long Short-Term Memory(LSTM)networks,we apply it to identify sequential dependencies of user behavior and then incorporate an attention mechanism to improve the prioritization of relevant items,thereby enhancing recommendations based on the hybrid feedback of the user and its interaction patterns.The proposed system is empirically evaluated using publicly available datasets from movie and music,and we evaluate the performance against standard recommendation models,including Popularity,BPR,ItemKNN,FPMC,LightGCN,GRU4Rec,NARM,SASRec,and BERT4Rec.The results demonstrate that our proposed framework consistently achieves high outcomes in terms of HitRate,NDCG,MRR,and Precision at K=100,with scores of(0.6763,0.1892,0.0796,0.0068)on MovieLens-100K,(0.6826,0.1920,0.0813,0.0068)on MovieLens-1M,and(0.7937,0.3701,0.2756,0.0078)on Last.fm.The results show an average improvement of around 15%across all metrics compared to existing sequence models,proving that our framework ranks and recommends items more accurately. 展开更多
关键词 recommendation systems traditional collaborative filtering Bayesian personalized ranking
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CIT-Rec:Enhancing Sequential Recommendation System with Large Language Models
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作者 Ziyu Li Zhen Chen +2 位作者 Xuejing Fu Tong Mo Weiping Li 《Computers, Materials & Continua》 2026年第3期2328-2343,共16页
Recommendation systems are key to boosting user engagement,satisfaction,and retention,particularly on media platforms where personalized content is vital.Sequential recommendation systems learn from user-item interact... Recommendation systems are key to boosting user engagement,satisfaction,and retention,particularly on media platforms where personalized content is vital.Sequential recommendation systems learn from user-item interactions to predict future items of interest.However,many current methods rely on unique user and item IDs,limiting their ability to represent users and items effectively,especially in zero-shot learning scenarios where training data is scarce.With the rapid development of Large Language Models(LLMs),researchers are exploring their potential to enhance recommendation systems.However,there is a semantic gap between the linguistic semantics of LLMs and the collaborative semantics of recommendation systems,where items are typically indexed by IDs.Moreover,most research focuses on item representations,neglecting personalized user modeling.To address these issues,we propose a sequential recommendation framework using LLMs,called CIT-Rec,a model that integrates Collaborative semantics for user representation and Image and Text information for item representation to enhance Recommendations.Specifically,by aligning intuitive image information with text containing semantic features,we can more accurately represent items,improving item representation quality.We focus not only on item representations but also on user representations.To more precisely capture users’personalized preferences,we use traditional sequential recommendation models to train on users’historical interaction data,effectively capturing behavioral patterns.Finally,by combining LLMs and traditional sequential recommendation models,we allow the LLM to understand linguistic semantics while capturing collaborative semantics.Extensive evaluations on real-world datasets show that our model outperforms baseline methods,effectively combining user interaction history with item visual and textual modalities to provide personalized recommendations. 展开更多
关键词 Large language models vision language models sequential recommendation instruction tuning
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Conditional Generative Adversarial Network-Based Travel Route Recommendation
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作者 Sunbin Shin Luong Vuong Nguyen +3 位作者 Grzegorz J.Nalepa Paulo Novais Xuan Hau Pham Jason J.Jung 《Computers, Materials & Continua》 2026年第1期1178-1217,共40页
Recommending personalized travel routes from sparse,implicit feedback poses a significant challenge,as conventional systems often struggle with information overload and fail to capture the complex,sequential nature of... Recommending personalized travel routes from sparse,implicit feedback poses a significant challenge,as conventional systems often struggle with information overload and fail to capture the complex,sequential nature of user preferences.To address this,we propose a Conditional Generative Adversarial Network(CGAN)that generates diverse and highly relevant itineraries.Our approach begins by constructing a conditional vector that encapsulates a user’s profile.This vector uniquely fuses embeddings from a Heterogeneous Information Network(HIN)to model complex user-place-route relationships,a Recurrent Neural Network(RNN)to capture sequential path dynamics,and Neural Collaborative Filtering(NCF)to incorporate collaborative signals from the wider user base.This comprehensive condition,further enhanced with features representing user interaction confidence and uncertainty,steers a CGAN stabilized by spectral normalization to generate high-fidelity latent route representations,effectively mitigating the data sparsity problem.Recommendations are then formulated using an Anchor-and-Expand algorithm,which selects relevant starting Points of Interest(POI)based on user history,then expands routes through latent similarity matching and geographic coherence optimization,culminating in Traveling Salesman Problem(TSP)-based route optimization for practical travel distances.Experiments on a real-world check-in dataset validate our model’s unique generative capability,achieving F1 scores ranging from 0.163 to 0.305,and near-zero pairs−F1 scores between 0.002 and 0.022.These results confirm the model’s success in generating novel travel routes by recommending new locations and sequences rather than replicating users’past itineraries.This work provides a robust solution for personalized travel planning,capable of generating novel and compelling routes for both new and existing users by learning from collective travel intelligence. 展开更多
关键词 Travel route recommendation conditional generative adversarial network heterogeneous information network anchor-and-expand algorithm
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LLMKB:Large Language Models with Knowledge Base Augmentation for Conversational Recommendation
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作者 FANG Xiu QIU Sijia +1 位作者 SUN Guohao LU Jinhu 《Journal of Donghua University(English Edition)》 2026年第1期91-103,共13页
Conversational recommender systems(CRSs)focus on refining preferences and providing personalized recommendations through natural language interactions and dialogue history.Large language models(LLMs)have shown outstan... Conversational recommender systems(CRSs)focus on refining preferences and providing personalized recommendations through natural language interactions and dialogue history.Large language models(LLMs)have shown outstanding performance across various domains,thereby prompting researchers to investigate their applicability in recommendation systems.However,due to the lack of task-specific knowledge and an inefficient feature extraction process,LLMs still have suboptimal performance in recommendation tasks.Therefore,external knowledge sources,such as knowledge graphs(KGs)and knowledge bases(KBs),are often introduced to address the issue of data sparsity.Compared to KGs,KBs possess higher retrieval efficiency,making them more suitable for scenarios where LLMs serve as recommenders.To this end,we introduce a novel framework integrating LLMs with KBs for enhanced retrieval generation,namely LLMKB.LLMKB initially leverages structured knowledge to create mapping dictionaries,extracting entity-relation information from heterogeneous knowledge to construct KBs.Then,LLMKB achieves the embedding calibration between user information representations and documents in KBs through retrieval model fine-tuning.Finally,LLMKB employs retrievalaugmented generation to produce recommendations based on fused text inputs,followed by post-processing.Experiment results on two public CRS datasets demonstrate the effectiveness of our framework.Our code is publicly available at the link:https://anonymous.4open.science/r/LLMKB-6FD0. 展开更多
关键词 recommender system large language model(LLM) knowledge base(KB)
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Accurate closed-form flutter eigensolutions of three-dimensional composite laminates with shear deformation
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作者 Dezhuang PAN Yufeng XING 《Chinese Journal of Aeronautics》 2026年第1期230-246,共17页
According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing ... According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing differential equations are derived by the Hamilton's variational principle,and then solved by the iterative Separation-of-Variable(i SOV)method,which are applicable to arbitrary combinations of homogeneous Boundary Conditions(BCs).However,only the simply-support,clamped and cantilever panels are considered in this work for the sake of clarity.With the closed-form eigensolutions,the flutter frequency,flutter mode and flutter boundary are presented,and the effect of shear deformation and aerodynamic damping on flutter frequencies is investigated.Besides,the relation between panel energy and the work of aerodynamic load is discussed.The numerical comparisons reveal the following.(A)The flutter eigenvalues obtained by the present method are accurate,validated by the Finite Element Method(FEM)and the Galerkin method.(B)When the span-chord ratio is larger than 3,simplifying a 3D panel to 2D(two-dimensional)panel is reasonable and the relative differences of the flutter points predicted by the two models are less than one percent.(C)The reciprocal relationship between the mechanical energy of the panel and the work done by aerodynamic load is verified by using the present flutter eigenvalues and modes,further indicating the high accuracy of the present solutions.(D)The coupling of shear deformation and aerodynamic damping prevents frequency coalescing. 展开更多
关键词 Closed-form eigensolutions The first-order piston theory The Mindlin plate theory three-dimensional panel flutter Separation-of-variable method
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Three-dimensional line-of-sight-angle-constrained leader-following cooperative interception guidance law with prespecified impact time 被引量:3
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作者 Hao YOU Xinlong CHANG Jiufen ZHAO 《Chinese Journal of Aeronautics》 2025年第1期491-506,共16页
To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea... To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law. 展开更多
关键词 three-dimensional cooperative interception Leader-following missiles Prespecified impact time LOS-angle-constrained Fixed-time stability Global integral sliding mode
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A Cross Attention Transformer-Mixed Feedback Video Recommendation Algorithm Based on DIEN
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作者 Jianwei Zhang Zhishang Zhao +3 位作者 Zengyu Cai Yuan Feng Liang Zhu Yahui Sun 《Computers, Materials & Continua》 SCIE EI 2025年第1期977-996,共20页
The rapid development of short video platforms poses new challenges for traditional recommendation systems.Recommender systems typically depend on two types of user behavior feedback to construct user interest profile... The rapid development of short video platforms poses new challenges for traditional recommendation systems.Recommender systems typically depend on two types of user behavior feedback to construct user interest profiles:explicit feedback(interactive behavior),which significantly influences users’short-term interests,and implicit feedback(viewing time),which substantially affects their long-term interests.However,the previous model fails to distinguish between these two feedback methods,leading it to predict only the overall preferences of users based on extensive historical behavior sequences.Consequently,it cannot differentiate between users’long-term and shortterm interests,resulting in low accuracy in describing users’interest states and predicting the evolution of their interests.This paper introduces a video recommendationmodel calledCAT-MFRec(CrossAttention Transformer-Mixed Feedback Recommendation)designed to differentiate between explicit and implicit user feedback within the DIEN(Deep Interest Evolution Network)framework.This study emphasizes the separate learning of the two types of behavioral feedback,effectively integrating them through the cross-attention mechanism.Additionally,it leverages the long sequence dependence capabilities of Transformer technology to accurately construct user interest profiles and predict the evolution of user interests.Experimental results indicate that CAT-MF Rec significantly outperforms existing recommendation methods across various performance indicators.This advancement offers new theoretical and practical insights for the development of video recommendations,particularly in addressing complex and dynamic user behavior patterns. 展开更多
关键词 Video recommendation user interest cross-attention TRANSFORMER
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Global Mapping of Three-Dimensional Urban Structures Reveals Escalating Utilization in the Vertical Dimension and Pronounced Building Space Inequality 被引量:1
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作者 Xiaoping Liu Xinxin Wu +6 位作者 Xuecao Li Xiaocong Xu Weilin Liao Limin Jiao Zhenzhong Zeng Guangzhao Chen Xia Li 《Engineering》 2025年第4期86-99,共14页
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan... Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies. 展开更多
关键词 three-dimensional Global mapping Building volume Building height Building space inequality
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Three-dimensional reconstruction under computed tomography and myopectineal orifice measurement under laparoscopy for quality control of inguinal hernia treatment 被引量:1
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作者 Lei Zhang Jing Chen +7 位作者 Yu-Ying Zhang Lei Liu Han-Dan Wang Ya-Fei Zhang Jun Sheng Qiu-Shi Hu Ming-Liang Liu Yi-Lin Yuan 《World Journal of Gastrointestinal Endoscopy》 2025年第3期50-59,共10页
BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are ne... BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are necessary.However,due to differences in race and sex,people’s body shapes vary.According to European guidelines,the patch should measure 10 cm×15 cm.If any part of the MPO is dissected,injury to the nerves,vascular network,or organs may occur during surgery,thereby leading to inguinal discomfort,pain,and seroma formation after surgery.Therefore,accurate localization and measurement of the boundary of the MPO are crucial for selecting the optimal patch for inguinal hernia repair.AIM To compare the size of the MPO measured on three-dimensional multislice spiral computed tomography(CT)with that measured via laparoscopy and explore the relevant factors influencing the size of the MPO.METHODS Clinical data from 74 patients who underwent laparoscopic tension-free inguinal hernia repair at the General Surgery Department of the First Affiliated Hospital of Anhui University of Science and Technology between September 2022 and July 2024 were collected and analyzed retrospectively.Transabdominal preperitoneal was performed.Sixty-four males and 10 females,with an average age of 58.30±12.32 years,were included.The clinical data of the patients were collected.The boundary of the MPO was measured on three-dimensional CT images before surgery and then again during transabdominal preperitoneal.All the preoperative and intraoperative data were analyzed via paired t-tests.A t-test was used for comparisons of age,body mass index,and sex between the groups.In the comparative analysis,a P value less than 0.05 indicated a significant difference.RESULTS The boundaries of the MPO on 3-dimensional CT images measured 7.05±0.47 cm and 6.27±0.61 cm,and the area of the MPO was 19.54±3.33 cm^(2).The boundaries of the MPO during surgery were 7.18±0.51 cm and 6.17±0.40 cm.The errors were not statistically significant.However,the intraoperative BD(the width of the MPO,P=0.024,P<0.05)and preoperative AC(the length of the MPO,P=0.045,P<0.05)significantly differed according to sex.The AC and BD measurements before and during surgery were not significantly different according to age,body mass index,hernia side or hernia type(P>0.05).CONCLUSION The application of this technology can aid in determining the most appropriate dissection range and patch size. 展开更多
关键词 HERNIA INGUINAL Myopectineal orifice three-dimensional reconstruction Computed tomography Inguinal hernia
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Personal Style Guided Outfit Recommendation with Multi-Modal Fashion Compatibility Modeling 被引量:1
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作者 WANG Kexin ZHANG Jie +3 位作者 ZHANG Peng SUN Kexin ZHAN Jiamei WEI Meng 《Journal of Donghua University(English Edition)》 2025年第2期156-167,共12页
A personalized outfit recommendation has emerged as a hot research topic in the fashion domain.However,existing recommendations do not fully exploit user style preferences.Typically,users prefer particular styles such... A personalized outfit recommendation has emerged as a hot research topic in the fashion domain.However,existing recommendations do not fully exploit user style preferences.Typically,users prefer particular styles such as casual and athletic styles,and consider attributes like color and texture when selecting outfits.To achieve personalized outfit recommendations in line with user style preferences,this paper proposes a personal style guided outfit recommendation with multi-modal fashion compatibility modeling,termed as PSGNet.Firstly,a style classifier is designed to categorize fashion images of various clothing types and attributes into distinct style categories.Secondly,a personal style prediction module extracts user style preferences by analyzing historical data.Then,to address the limitations of single-modal representations and enhance fashion compatibility,both fashion images and text data are leveraged to extract multi-modal features.Finally,PSGNet integrates these components through Bayesian personalized ranking(BPR)to unify the personal style and fashion compatibility,where the former is used as personal style features and guides the output of the personalized outfit recommendation tailored to the target user.Extensive experiments on large-scale datasets demonstrate that the proposed model is efficient on the personalized outfit recommendation. 展开更多
关键词 personalized outfit recommendation fashion compatibility modeling style preference multi-modal representation Bayesian personalized ranking(BPR) style classifier
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Artificial intelligence-aided semi-automatic joint trace detection from textured three-dimensional models of rock mass 被引量:1
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作者 Seyedahmad Mehrishal Jineon Kim +1 位作者 Yulong Shao Jae Joon Song 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期1973-1985,共13页
It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimens... It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimensional(3D)models are relatively straightforward but time-consuming.One potential solution to enhance this process is to use machine learning algorithms to detect the 3D traces.In this study,a unique pixel-wise texture mapper algorithm generates a dense point cloud representation of an outcrop with the precise resolution of the original textured 3D model.A virtual digital image rendering was then employed to capture virtual images of selected regions.This technique helps to overcome limitations caused by the surface morphology of the rock mass,such as restricted access,lighting conditions,and shading effects.After AI-powered trace detection on two-dimensional(2D)images,a 3D data structuring technique was applied to the selected trace pixels.In the 3D data structuring,the trace data were structured through 2D thinning,3D reprojection,clustering,segmentation,and segment linking.Finally,the linked segments were exported as 3D polylines,with each polyline in the output corresponding to a trace.The efficacy of the proposed method was assessed using a 3D model of a real-world case study,which was used to compare the results of artificial intelligence(AI)-aided and human intelligence trace detection.Rosette diagrams,which visualize the distribution of trace orientations,confirmed the high similarity between the automatically and manually generated trace maps.In conclusion,the proposed semi-automatic method was easy to use,fast,and accurate in detecting the dominant jointing system of the rock mass. 展开更多
关键词 Automatic trace detection Digital joint mapping Rock discontinuities characterization three-dimensional(3D)trace network
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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions 被引量:1
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作者 Chentong GAO Huiyu SUN +1 位作者 Jianping GU W.M.HUANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第1期123-138,共16页
Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade compone... Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade components.In this paper,a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established.Based on Kirchhoff's plate assumptions,the displacement variables of the plate are expressed.By incorporating the braiding directions into the constitutive equation of the braided composites,the dynamic model of the plate considering braiding directions is obtained.The effects of the speeds,braiding directions,and braided angles on the responses of the plate with fixed-axis rotation and translational motion,respectively,are investigated.This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions.It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications. 展开更多
关键词 three-dimensional(3D)braided composite braiding direction composite thin plate large overall motion dynamic model
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Three-dimensional models:from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
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作者 SAYUMI TAHARA SYDNEY RENTSCH +4 位作者 FERNANDA COSTAS CASAL DE FARIA PATRICIA SARCHET ROMA KARNA FEDERICA CALORE RAPHAEL E.POLLOCK 《Oncology Research》 SCIE 2025年第1期1-13,共13页
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ... Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma. 展开更多
关键词 Cell culture LIPOSARCOMA Patient-Derived Organoid(PDO) SPHEROID three-dimensional(3D)cell culture
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Three-dimensional(3D)printing-assisted freeze-casting of processed pyritum-dopedβ-tricalcium phosphate biomimetic scaffold with angiogenesis and bone regeneration capability 被引量:1
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作者 Chenxu WEI Zongan LI +9 位作者 Xiaoyun LIANG Yuwei ZHAO Xingyu ZHU Haibing HUA Guobao CHEN Kunming QIN Zhipeng CHEN Changcan SHI Feng ZHANG Weidong LI 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 2025年第9期863-880,共18页
Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds ... Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds incorporated with processed pyritum decoction(PPD)were fabricated using three-dimensional(3D)printing-assisted freeze-casting.The produced composite scaffolds were evaluated for their mechanical strength,physicochemical properties,biocompatibility,in vitro proangiogenic activity,and in vivo efficacy in repairing rabbit femoral defects.They not only demonstrated excellent physicochemical properties,enhanced mechanical strength,and good biosafety but also significantly promoted the proliferation,migration,and aggregation of pro-angiogenic human umbilical vein endothelial cells(HUVECs).In vivo studies revealed that all scaffold groups facilitated osteogenesis at the bone defect site,with theβ-TCP scaffolds loaded with PPD markedly enhancing the expression of neurogenic locus Notch homolog protein 1(Notch1),vascular endothelial growth factor(VEGF),bone morphogenetic protein-2(BMP-2),and osteopontin(OPN).Overall,the scaffolds developed in this study exhibited strong angiogenic and osteogenic capabilities both in vitro and in vivo.The incorporation of PPD notably promoted the angiogenic-osteogenic coupling,thereby accelerating bone repair,which suggests that PPD is a promising material for bone repair and that the PPD/β-TCP scaffolds hold great potential as a bone graft alternative. 展开更多
关键词 Bone defect Processed pyritum three-dimensional(3D)printing-assisted freeze-casting ANGIOGENESIS Bone regeneration VEGF-Notch1-BMP-2-OPN coupling
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A New Fuzzy Number Similarity Measure Based on Quadratic-Mean Operator for Handling Fuzzy Recommendation Problems
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作者 Shijay Chen 《Journal of Computer and Communications》 2025年第1期108-124,共17页
This study presents a new approach that advances the algorithm of similarity measures between generalized fuzzy numbers. Following a brief introduction to some properties of the proposed method, a comparative analysis... This study presents a new approach that advances the algorithm of similarity measures between generalized fuzzy numbers. Following a brief introduction to some properties of the proposed method, a comparative analysis based on 36 sets of generalized fuzzy numbers was performed, in which the degree of similarity of the fuzzy numbers was calculated with the proposed method and seven methods established by previous studies in the literature. The results of the analytical comparison show that the proposed similarity outperforms the existing methods by overcoming their drawbacks and yielding accurate outcomes in all calculations of similarity measures under consideration. Finally, in a numerical example that involves recommending cars to customers based on a nine-member linguistic term set, the proposed similarity measure proves to be competent in addressing fuzzy number recommendation problems. 展开更多
关键词 Quadratic-Mean Operator Generalized Fuzzy Numbers Similarity Measures Fuzzy Number recommendation
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Glasses-free three-dimensional laparoscopic systems in oncologic surgery:Innovation or equivalence?
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作者 Gustavo Eder González Alvarez Christian Ramírez Sánchez +3 位作者 Melissa Martínez Nieto Mario A Alarcón-Sánchez Juan JoséVarela-Hernández Sarah M LomelíMartínez 《World Journal of Gastrointestinal Surgery》 2025年第11期6-11,共6页
The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a rece... The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a recent study by Shen and Zhang,which compared the clinical applications of naked-eye threedimensional laparoscopic systems vs traditional optical systems in radical surgery for gastric and colorectal cancer.Both systems appeared to yield comparable surgical and oncological outcomes in terms of safety parameters,operating times,and quality of lymph node dissection.However,the spectacle-free system’s technical and logistical limitations hindered its effects on the surgical team’s overall competency.This editorial examines the authors’findings within the broader context of the evolution of oncologic laparoscopy,discusses the relevance of the results in light of the current literature,and proposes future research directions focused on multicenter validation,comprehensive ergonomic analysis,and technological advancements aimed at enhancing intraoperative collaboration.As technology continues to evolve,clinical implementation of new methods must be supported by robust scientific evidence and standardized criteria,to ensure tangible improvements in efficiency,safety,and oncologic outcomes. 展开更多
关键词 Autostereoscopic three-dimensional technology Laparoscopic surgery three-dimensional laparoscopy Twodimensional laparoscopy Oncologic surgery
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Investigation into the degradation of 2,4,6-trichlorophenol utilizing a three-dimensional electrocatalytic reactor filled with fluorine-doped copper-carbon particle electrodes
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作者 Hongrui Zhang Wenyu Huang +4 位作者 Hainong Song Hanhui Yan Jia Zhang Fang Zhong Huilan Li 《Journal of Environmental Sciences》 2025年第9期701-719,共19页
The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated cata... The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated catalytic activity and minimal energy consumption continues to pose a significant challenge.In this research,Fluorine-doped copper-carbon(F/Cu-GAC)particle electrodes were effectively synthesized through an impregnationcalcination technique,utilizing granular activated carbon as the carrier and fluorinedoped modified copper oxides as the catalytic agents.The particle electrodes were subsequently utilized to promote the degradation of 2,4,6-trichlorophenol(2,4,6-TCP)in a threedimensional electrocatalytic reactor(3DER).The F/Cu-GAC particle electrodes were polarized under the action of electric field,which promoted the heterogeneous Fenton-like reaction in which H2O2 generated by two-electron oxygen reduction reaction(2e-ORR)of O_(2) was catalytically decomposed to·OH.The 3DER equipped with F/Cu-GAC particle electrodes showed 100%removal of 2,4,6-TCP and 79.24%removal of TOC with a specific energy consumption(EC)of approximately 0.019 kWh/g·COD after 2 h of operation.The F/Cu-GAC particle electrodes exhibited an overpotential of 0.38 V and an electrochemically active surface area(ECSA)of 715 cm^(2),as determined through linear sweep voltammetry(LSV)and cyclic voltammetry(CV)assessments.These findings suggest a high level of electrocatalytic performance.Furthermore,the catalytic mechanism of the 3DER equipped with F/Cu-GAC particle electrodes was elucidated through the application of X-ray photoelectron spectroscopy(XPS),electron spin resonance(ESR),and active species capture experiments.This investigation offers a novel approach for the effective degradation of 2,4,6-TCP. 展开更多
关键词 2 4 6-TRICHLOROPHENOL Heterogeneous Fenton-like process three-dimensional electrocatalytic reactor three-dimensional particle electrode system Fluorine-doped copper-carbon particle electrodes
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HMGS:Hierarchical Matching Graph Neural Network for Session-Based Recommendation
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作者 Pengfei Zhang Rui Xin +5 位作者 Xing Xu Yuzhen Wang Xiaodong Li Xiao Zhang Meina Song Zhonghong Ou 《Computers, Materials & Continua》 2025年第6期5413-5428,共16页
Session-based recommendation systems(SBR)are pivotal in suggesting items by analyzing anonymized sequences of user interactions.Traditional methods,while competent,often fall short in two critical areas:they fail to a... Session-based recommendation systems(SBR)are pivotal in suggesting items by analyzing anonymized sequences of user interactions.Traditional methods,while competent,often fall short in two critical areas:they fail to address potential inter-session item transitions,which are behavioral dependencies that extend beyond individual session boundaries,and they rely on monolithic item aggregation to construct session representations.This approach does not capture the multi-scale and heterogeneous nature of user intent,leading to a decrease in modeling accuracy.To overcome these limitations,a novel approach called HMGS has been introduced.This system incorporates dual graph architectures to enhance the recommendation process.A global transition graph captures latent cross-session item dependencies,while a heterogeneous intra-session graph encodesmulti-scale item embeddings through localized feature propagation.Additionally,amulti-tier graphmatchingmechanism aligns user preference signals across different granularities,significantly improving interest localization accuracy.Empirical validation on benchmark datasets(Tmall and Diginetica)confirms HMGS’s efficacy against state-of-the-art baselines.Quantitative analysis reveals performance gains of 20.54%and 12.63%in Precision@10 on Tmall and Diginetica,respectively.Consistent improvements are observed across auxiliary metrics,with MRR@10,Precision@20,and MRR@20 exhibiting enhancements between 4.00%and 21.36%,underscoring the framework’s robustness in multi-faceted recommendation scenarios. 展开更多
关键词 Session-based recommendation graph network multi-level matching
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HyTiFRec:Hybrid Time-Frequency Dual-Branch Transformer for Sequential Recommendation
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作者 Dawei Qiu Peng Wu +1 位作者 Xiaoming Zhang Renjie Xu 《Computers, Materials & Continua》 2025年第5期1753-1769,共17页
Recently,many Sequential Recommendation methods adopt self-attention mechanisms to model user preferences.However,these methods tend to focus more on low-frequency information while neglecting highfrequency informatio... Recently,many Sequential Recommendation methods adopt self-attention mechanisms to model user preferences.However,these methods tend to focus more on low-frequency information while neglecting highfrequency information,which makes them ineffective in balancing users’long-and short-term preferences.At the same time,manymethods overlook the potential of frequency domainmethods,ignoring their efficiency in processing frequency information.To overcome this limitation,we shift the focus to the combination of time and frequency domains and propose a novel Hybrid Time-Frequency Dual-Branch Transformer for Sequential Recommendation,namely HyTiFRec.Specifically,we design two hybrid filter modules:the learnable hybrid filter(LHF)and the window hybrid filter(WHF).We combine these with the Efficient Attention(EA)module to form the dual-branch structure to replace the self-attention components in Transformers.The EAmodule is used to extract sequential and global information.The LHF andWHF modules balance the proportion of different frequency bands,with LHF globally modulating the spectrum in the frequency domain and WHF retaining frequency components within specific local frequency bands.Furthermore,we use a time domain residual information addition operation in the hybrid filter module,which reduces information loss and further facilitates the hybrid of time-frequency methods.Extensive experiments on five widely-used real-world datasets show that our proposed method surpasses state-of-the-art methods. 展开更多
关键词 Sequential recommendation frequency domain efficient attention
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