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Cosmic Acceleration and the Hubble Tension from Baryon Acoustic Oscillation Data
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作者 Xuchen Lu Shengqing Gao Yungui Gong 《Chinese Physics Letters》 2026年第1期327-332,共6页
We investigate the null tests of cosmic accelerated expansion by using the baryon acoustic oscillation(BAO)data measured by the dark energy spectroscopic instrument(DESI)and reconstruct the dimensionless Hubble parame... We investigate the null tests of cosmic accelerated expansion by using the baryon acoustic oscillation(BAO)data measured by the dark energy spectroscopic instrument(DESI)and reconstruct the dimensionless Hubble parameter E(z)from the DESI BAO Alcock-Paczynski(AP)data using Gaussian process to perform the null test.We find strong evidence of accelerated expansion from the DESI BAO AP data.By reconstructing the deceleration parameter q(z) from the DESI BAO AP data,we find that accelerated expansion persisted until z■0.7 with a 99.7%confidence level.Additionally,to provide insights into the Hubble tension problem,we propose combining the reconstructed E(z) with D_(H)/r_(d) data to derive a model-independent result r_(d)h=99.8±3.1 Mpc.This result is consistent with measurements from cosmic microwave background(CMB)anisotropies using the ΛCDM model.We also propose a model-independent method for reconstructing the comoving angular diameter distance D_(M)(z) from the distance modulus μ,using SNe Ia data and combining this result with DESI BAO data of D_(M)/r_(d) to constrain the value of r_(d).We find that the value of r_(d),derived from this model-independent method,is smaller than that obtained from CMB measurements,with a significant discrepancy of at least 4.17σ.All the conclusions drawn in this paper are independent of cosmological models and gravitational theories. 展开更多
关键词 baryon acoustic oscillation bao data cosmic accelerated expansion dimensionless hubble parameter reconstructing deceleration parameter null testwe accelerated expansion null tests gaussian process
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Accurate closed-form flutter eigensolutions of three-dimensional composite laminates with shear deformation
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作者 Dezhuang PAN Yufeng XING 《Chinese Journal of Aeronautics》 2026年第1期230-246,共17页
According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing ... According to the Mindlin plate theory and the first-order piston theory,this work obtains accurate closed-form eigensolutions for the flutter problem of three-dimensional(3D)rectangular laminated panels.The governing differential equations are derived by the Hamilton's variational principle,and then solved by the iterative Separation-of-Variable(i SOV)method,which are applicable to arbitrary combinations of homogeneous Boundary Conditions(BCs).However,only the simply-support,clamped and cantilever panels are considered in this work for the sake of clarity.With the closed-form eigensolutions,the flutter frequency,flutter mode and flutter boundary are presented,and the effect of shear deformation and aerodynamic damping on flutter frequencies is investigated.Besides,the relation between panel energy and the work of aerodynamic load is discussed.The numerical comparisons reveal the following.(A)The flutter eigenvalues obtained by the present method are accurate,validated by the Finite Element Method(FEM)and the Galerkin method.(B)When the span-chord ratio is larger than 3,simplifying a 3D panel to 2D(two-dimensional)panel is reasonable and the relative differences of the flutter points predicted by the two models are less than one percent.(C)The reciprocal relationship between the mechanical energy of the panel and the work done by aerodynamic load is verified by using the present flutter eigenvalues and modes,further indicating the high accuracy of the present solutions.(D)The coupling of shear deformation and aerodynamic damping prevents frequency coalescing. 展开更多
关键词 Closed-form eigensolutions The first-order piston theory The Mindlin plate theory three-dimensional panel flutter Separation-of-variable method
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Effects of initial spin orientation on the generation of polarized electron beams from laser wakefield acceleration in plasma
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作者 L.R.Yin X.F.Li +6 位作者 Y.J.Gu N.Cao Q.Kong M.Büscher S.M.Weng M.Chen Z.M.Sheng 《Matter and Radiation at Extremes》 2026年第1期20-28,共9页
The effects of initial spin orientation on the final electron beam polarization in laser wakefield acceleration in a pre-polarized plasma are investigated theoretically and numerically.From the results of variation of... The effects of initial spin orientation on the final electron beam polarization in laser wakefield acceleration in a pre-polarized plasma are investigated theoretically and numerically.From the results of variation of the initial spin direction,the spin dynamics of the electron beam are found to depend on the self-injection mechanism.The effects of wakefields and laser fields are studied using test particle dynamics and particle-in-cell simulations based on the Thomas-Bargmann-Michel-Telegdi equation.Compared with transverse injection,longitudinal injection is found to be preferable for obtaining a highly polarized electron beam. 展开更多
关键词 spin dynamics laser fields test particle dynamics initial spin orientation electron beam laser wakefield acceleration electron beam polarization
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Resilient self-centering viscous-based bracing with SMA and friction springs:Multi-objective control of displacement and acceleration-an analytical study
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作者 Navid Rahgozar M.Shahria Alam 《Resilient Cities and Structures》 2026年第1期133-150,共18页
Self-Centering Piston-Based Braced Frames(SC-PBBFs)are designed to curtail structural damage under severe ground motions.The self-centering mechanism in this bracing mitigates structural damage during an earthquake,th... Self-Centering Piston-Based Braced Frames(SC-PBBFs)are designed to curtail structural damage under severe ground motions.The self-centering mechanism in this bracing mitigates structural damage during an earthquake,thereby reducing post-earthquake repair costs and contributing to seismic resilience.However,non-structural components,particularly those sensitive to floor acceleration,remain vulnerable,resulting in prolonged func-tional recovery times.This paper aims to address this limitation by introducing a novel structural archetype,the Self-Centering Viscous-Based Braced Frame(SC-VBBF),which integrates superelastic shape memory alloy(SMA)bars,viscous dampers(VDs),and friction springs(FSs).A streamlined analytical approach relies on the strength decoupling of VD from other components using aλfactor to design SC-VBBFs.To evaluate the effectiveness of the hybrid brace,a set of 4-,8-,and 12-story archetypes equipped with SC-PBBs and SC-VBBFs are simulated in OpenSees and analyzed under various earthquake types,including crustal,subcrustal,and subduction events.The results demonstrate the superior performance of the SC-VBBF withλ≤0.5 system compared to SC-PBBFs in mitigating floor accelerations under design-level earthquakes and improving seismic resilience. 展开更多
关键词 SELF-CENTERING Piston-based braced frame Self-centering viscous-based brace Shape memory alloy Viscous damper Friction spring Seismic analysis Design procedure acceleration control
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An Improved Graphics Processing Unit Acceleration Approach for Three-Dimensional Structural Topology Optimization Using the Element-Free Galerkin Method 被引量:1
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作者 Haishan Lu Shuguang Gong +2 位作者 Jianping Zhang Guilan Xie Shuohui Yin 《Computer Modeling in Engineering & Sciences》 SCIE EI 2021年第9期1151-1178,共28页
We proposed an improved graphics processing unit(GPU)acceleration approach for three-dimensional structural topology optimization using the element-free Galerkin(EFG)method.This method can effectively eliminate the ra... We proposed an improved graphics processing unit(GPU)acceleration approach for three-dimensional structural topology optimization using the element-free Galerkin(EFG)method.This method can effectively eliminate the race condition under parallelization.We established a structural topology optimization model by combining the EFG method and the solid isotropic microstructures with penalization model.We explored the GPU parallel algorithm of assembling stiffness matrix,solving discrete equation,analyzing sensitivity,and updating design variables in detail.We also proposed a node pair-wise method for assembling the stiffnessmatrix and a node-wise method for sensitivity analysis to eliminate race conditions during the parallelization.Furthermore,we investigated the effects of the thread block size,the number of degrees of freedom,and the convergence error of preconditioned conjugate gradient(PCG)on GPU computing performance.Finally,the results of the three numerical examples demonstrated the validity of the proposed approach and showed the significant acceleration of structural topology optimization.To save the cost of optimization calculation,we proposed the appropriate thread block size and the convergence error of the PCG method. 展开更多
关键词 Topology optimization EFG method GPU acceleration race condition preconditioned conjugate gradient
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Three-dimensional line-of-sight-angle-constrained leader-following cooperative interception guidance law with prespecified impact time 被引量:3
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作者 Hao YOU Xinlong CHANG Jiufen ZHAO 《Chinese Journal of Aeronautics》 2025年第1期491-506,共16页
To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D lea... To address the problem of multi-missile cooperative interception against maneuvering targets at a prespecified impact time and desired Line-of-Sight(LOS)angles in ThreeDimensional(3D)space,this paper proposes a 3D leader-following cooperative interception guidance law.First,in the LOS direction of the leader,an impact time-controlled guidance law is derived based on the fixed-time stability theory,which enables the leader to complete the interception task at a prespecified impact time.Next,in the LOS direction of the followers,by introducing a time consensus tracking error function,a fixed-time consensus tracking guidance law is investigated to guarantee the consensus tracking convergence of the time-to-go.Then,in the direction normal to the LOS,by combining the designed global integral sliding mode surface and the second-order Sliding Mode Control(SMC)theory,an innovative 3D LOS-angle-constrained interception guidance law is developed,which eliminates the reaching phase in the traditional sliding mode guidance laws and effectively saves energy consumption.Moreover,it effectively suppresses the chattering phenomenon while avoiding the singularity issue,and compensates for unknown interference caused by target maneuvering online,making it convenient for practical engineering applications.Finally,theoretical proof analysis and multiple sets of numerical simulation results verify the effectiveness,superiority,and robustness of the investigated guidance law. 展开更多
关键词 three-dimensional cooperative interception Leader-following missiles Prespecified impact time LOS-angle-constrained Fixed-time stability Global integral sliding mode
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Global Mapping of Three-Dimensional Urban Structures Reveals Escalating Utilization in the Vertical Dimension and Pronounced Building Space Inequality 被引量:1
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作者 Xiaoping Liu Xinxin Wu +6 位作者 Xuecao Li Xiaocong Xu Weilin Liao Limin Jiao Zhenzhong Zeng Guangzhao Chen Xia Li 《Engineering》 2025年第4期86-99,共14页
Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significan... Three-dimensional(3D)urban structures play a critical role in informing climate mitigation strategies aimed at the built environment and facilitating sustainable urban development.Regrettably,there exists a significant gap in detailed and consistent data on 3D building space structures with global coverage due to the challenges inherent in the data collection and model calibration processes.In this study,we constructed a global urban structure(GUS-3D)dataset,including building volume,height,and footprint information,at a 500 m spatial resolution using extensive satellite observation products and numerous reference building samples.Our analysis indicated that the total volume of buildings worldwide in2015 exceeded 1×10^(12)m^(3).Over the 1985 to 2015 period,we observed a slight increase in the magnitude of 3D building volume growth(i.e.,it increased from 166.02 km3 during the 1985–2000 period to 175.08km3 during the 2000–2015 period),while the expansion magnitudes of the two-dimensional(2D)building footprint(22.51×10^(3) vs 13.29×10^(3)km^(2))and urban extent(157×10^(3) vs 133.8×10^(3)km^(2))notably decreased.This trend highlights the significant increase in intensive vertical utilization of urban land.Furthermore,we identified significant heterogeneity in building space provision and inequality across cities worldwide.This inequality is particularly pronounced in many populous Asian cities,which has been overlooked in previous studies on economic inequality.The GUS-3D dataset shows great potential to deepen our understanding of the urban environment and creates new horizons for numerous 3D urban studies. 展开更多
关键词 three-dimensional Global mapping Building volume Building height Building space inequality
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Three-dimensional reconstruction under computed tomography and myopectineal orifice measurement under laparoscopy for quality control of inguinal hernia treatment 被引量:1
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作者 Lei Zhang Jing Chen +7 位作者 Yu-Ying Zhang Lei Liu Han-Dan Wang Ya-Fei Zhang Jun Sheng Qiu-Shi Hu Ming-Liang Liu Yi-Lin Yuan 《World Journal of Gastrointestinal Endoscopy》 2025年第3期50-59,共10页
BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are ne... BACKGROUND Inguinal hernias are common after surgery.Tension-free repair is widely accepted as the main method for managing inguinal hernias.Adequate exposure,coverage,and repair of the myopectineal orifice(MPO)are necessary.However,due to differences in race and sex,people’s body shapes vary.According to European guidelines,the patch should measure 10 cm×15 cm.If any part of the MPO is dissected,injury to the nerves,vascular network,or organs may occur during surgery,thereby leading to inguinal discomfort,pain,and seroma formation after surgery.Therefore,accurate localization and measurement of the boundary of the MPO are crucial for selecting the optimal patch for inguinal hernia repair.AIM To compare the size of the MPO measured on three-dimensional multislice spiral computed tomography(CT)with that measured via laparoscopy and explore the relevant factors influencing the size of the MPO.METHODS Clinical data from 74 patients who underwent laparoscopic tension-free inguinal hernia repair at the General Surgery Department of the First Affiliated Hospital of Anhui University of Science and Technology between September 2022 and July 2024 were collected and analyzed retrospectively.Transabdominal preperitoneal was performed.Sixty-four males and 10 females,with an average age of 58.30±12.32 years,were included.The clinical data of the patients were collected.The boundary of the MPO was measured on three-dimensional CT images before surgery and then again during transabdominal preperitoneal.All the preoperative and intraoperative data were analyzed via paired t-tests.A t-test was used for comparisons of age,body mass index,and sex between the groups.In the comparative analysis,a P value less than 0.05 indicated a significant difference.RESULTS The boundaries of the MPO on 3-dimensional CT images measured 7.05±0.47 cm and 6.27±0.61 cm,and the area of the MPO was 19.54±3.33 cm^(2).The boundaries of the MPO during surgery were 7.18±0.51 cm and 6.17±0.40 cm.The errors were not statistically significant.However,the intraoperative BD(the width of the MPO,P=0.024,P<0.05)and preoperative AC(the length of the MPO,P=0.045,P<0.05)significantly differed according to sex.The AC and BD measurements before and during surgery were not significantly different according to age,body mass index,hernia side or hernia type(P>0.05).CONCLUSION The application of this technology can aid in determining the most appropriate dissection range and patch size. 展开更多
关键词 HERNIA INGUINAL Myopectineal orifice three-dimensional reconstruction Computed tomography Inguinal hernia
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Evaluation of whole-course three-dimensional conformal radiotherapy combined with late-course accelerated hyperfractionated radiotherapy for esophageal carcinoma patients 被引量:1
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作者 Dianfu Zhang Peliang Zhang Yuguo Wang Shuren Cao Ruiyan Fang Yichang Liu Tao Zhang 《The Chinese-German Journal of Clinical Oncology》 CAS 2011年第3期144-146,共3页
Objective: The aim of the study was to evaluate the therapeutic effect and safety of whole-course three-dimensional conformal radiotherapy (3DCRT) combined with late-course accelerated hyperfractionated radiothera... Objective: The aim of the study was to evaluate the therapeutic effect and safety of whole-course three-dimensional conformal radiotherapy (3DCRT) combined with late-course accelerated hyperfractionated radiotherapy (LCAFR) on patients with esophageal carcinoma. Methods: one hundred and one patients with esophageal carcinoma were divided into two groups. Observing group (49 cases) were treated by whole-course 3DCRT. Patients in control group (52 cases) were treated by conventional radiotherapy. Clinical efficiencies and radiation toxicities were compared between two groups. Results: The side effects including radiation esophagitis (63.2%) and tracheitis (49.0%) decreased in observing group, but there was no significant difference between two groups (69.2% and 55.7% in controls). The 1-, 2-and 3-year tumor local control rates and overall survival rates in the observing group were significantly improved compared with the control group, being respectively 87.8%, 75.5%, 63.3% vs 71.2%, 55.8%, 42.3% and 85.7%, 71.4%, 46.7% vs 69.2%, 51.9%, 26.9% (all P 0.05). Conclusion: The therapeutic effect of whole-course 3DCRT combined with LCAFR for esophageal carcinomas is superior to conventional radiotherapy. 展开更多
关键词 esophageal neoplasms three-dimensional conformal radiotherapy (3DCRT) late-course accelerated hyperfractionated radiotherapy (LCAFR)
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GPU-accelerated three-dimensional reconstruction method of the Compton camera and its application in radionuclide imaging 被引量:1
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作者 Ren-Yao Wu Chang-Ran Geng +6 位作者 Feng Tian Zhi-Yang Yao Chun-Hui Gong Hao-Nan Han Jian-Feng Xu Yong-Shun Xiao Xiao-Bin Tang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第4期54-68,共15页
A novel and fast three-dimensional reconstruction method for a Compton camera and its performance in radionuclide imaging is proposed and analyzed in this study. The conical surface sampling back-projection method wit... A novel and fast three-dimensional reconstruction method for a Compton camera and its performance in radionuclide imaging is proposed and analyzed in this study. The conical surface sampling back-projection method with scattering angle correction(CSS-BP-SC) can quickly perform the back-projection process of the Compton cone and can be used to precompute the list-mode maximum likelihood expectation maximization(LM-MLEM). A dedicated parallel architecture was designed for the graphics processing unit acceleration of the back-projection and iteration stage of the CSS-BP-SC-based LM-MLEM. The imaging results of the two-point source Monte Carlo(MC) simulation demonstrate that by analyzing the full width at half maximum along the three coordinate axes, the CSS-BP-SC-based LM-MLEM can obtain imaging results comparable to those of the traditional reconstruction algorithm, that is, the simple back-projection-based LM-MLEM. The imaging results of the mouse phantom MC simulation and experiment demonstrate that the reconstruction results obtained by the proposed method sufficiently coincide with the set radioactivity distribution, and the speed increased by more than 664 times compared to the traditional reconstruction algorithm in the mouse phantom experiment. The proposed method will further advance the imaging applications of Compton cameras. 展开更多
关键词 Compton camera three-dimensional reconstruction Radionuclide imaging GPU
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Artificial intelligence-aided semi-automatic joint trace detection from textured three-dimensional models of rock mass 被引量:1
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作者 Seyedahmad Mehrishal Jineon Kim +1 位作者 Yulong Shao Jae Joon Song 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期1973-1985,共13页
It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimens... It is of great importance to obtain precise trace data,as traces are frequently the sole visible and measurable parameter in most outcrops.The manual recognition and detection of traces on high-resolution three-dimensional(3D)models are relatively straightforward but time-consuming.One potential solution to enhance this process is to use machine learning algorithms to detect the 3D traces.In this study,a unique pixel-wise texture mapper algorithm generates a dense point cloud representation of an outcrop with the precise resolution of the original textured 3D model.A virtual digital image rendering was then employed to capture virtual images of selected regions.This technique helps to overcome limitations caused by the surface morphology of the rock mass,such as restricted access,lighting conditions,and shading effects.After AI-powered trace detection on two-dimensional(2D)images,a 3D data structuring technique was applied to the selected trace pixels.In the 3D data structuring,the trace data were structured through 2D thinning,3D reprojection,clustering,segmentation,and segment linking.Finally,the linked segments were exported as 3D polylines,with each polyline in the output corresponding to a trace.The efficacy of the proposed method was assessed using a 3D model of a real-world case study,which was used to compare the results of artificial intelligence(AI)-aided and human intelligence trace detection.Rosette diagrams,which visualize the distribution of trace orientations,confirmed the high similarity between the automatically and manually generated trace maps.In conclusion,the proposed semi-automatic method was easy to use,fast,and accurate in detecting the dominant jointing system of the rock mass. 展开更多
关键词 Automatic trace detection Digital joint mapping Rock discontinuities characterization three-dimensional(3D)trace network
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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions 被引量:1
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作者 Chentong GAO Huiyu SUN +1 位作者 Jianping GU W.M.HUANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第1期123-138,共16页
Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade compone... Currently,there are a limited number of dynamic models available for braided composite plates with large overall motions,despite the incorporation of three-dimensional(3D)braided composites into rotating blade components.In this paper,a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established.Based on Kirchhoff's plate assumptions,the displacement variables of the plate are expressed.By incorporating the braiding directions into the constitutive equation of the braided composites,the dynamic model of the plate considering braiding directions is obtained.The effects of the speeds,braiding directions,and braided angles on the responses of the plate with fixed-axis rotation and translational motion,respectively,are investigated.This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions.It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications. 展开更多
关键词 three-dimensional(3D)braided composite braiding direction composite thin plate large overall motion dynamic model
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Predicting peak ground acceleration using the ConvMixer network 被引量:1
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作者 Mona Mohammed Omar M Saad +1 位作者 Arabi Keshk Hatem M Ahmed 《Earthquake Science》 2025年第2期126-135,共10页
The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the... The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the PGA immediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system.In this study,we propose a deep learning model,ConvMixer,to predict the PGA recorded by weak-motion velocity seismometers in Japan.We use 5-s threecomponent seismograms,from 2 s before until 3 s after the P-wave arrival time of the earthquake.Our dataset comprised more than 50,000 single-station waveforms recorded by 10 seismic stations in the K-NET,Kiki-NET,and Hi-Net networks between 2004 and 2023.The proposed ConvMixer is a patch-based model that extracts global features from input seismic data and predicts the PGA of an earthquake by combining depth and pointwise convolutions.The proposed ConvMixer network had a mean absolute error of 2.143 when applied to the test set and outperformed benchmark deep learning models.In addition,the proposed ConvMixer demonstrated the ability to predict the PGA at the corresponding station site based on 1-second waveforms obtained immediately after the arrival time of the P-wave. 展开更多
关键词 peak ground acceleration(PGA) earthquake early warning system(EEWS) deep learning(DL)
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Three-dimensional models:from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
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作者 SAYUMI TAHARA SYDNEY RENTSCH +4 位作者 FERNANDA COSTAS CASAL DE FARIA PATRICIA SARCHET ROMA KARNA FEDERICA CALORE RAPHAEL E.POLLOCK 《Oncology Research》 SCIE 2025年第1期1-13,共13页
Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma ... Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other cancers.Due to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma pathobiology.Conventional cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under discussion.In vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture.However,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)characteristics.Therefore,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between them.Given the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development.In this review,we first provide a general overview of 3D cell cultures compared to 2D cell cultures.We then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO methodologies.Finally,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma. 展开更多
关键词 Cell culture LIPOSARCOMA Patient-Derived Organoid(PDO) SPHEROID three-dimensional(3D)cell culture
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Three-dimensional(3D)printing-assisted freeze-casting of processed pyritum-dopedβ-tricalcium phosphate biomimetic scaffold with angiogenesis and bone regeneration capability 被引量:1
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作者 Chenxu WEI Zongan LI +9 位作者 Xiaoyun LIANG Yuwei ZHAO Xingyu ZHU Haibing HUA Guobao CHEN Kunming QIN Zhipeng CHEN Changcan SHI Feng ZHANG Weidong LI 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 2025年第9期863-880,共18页
Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds ... Bone repair remains an important target in tissue engineering,making the development of bioactive scaffolds for effective bone defect repair a critical objective.In this study,β-tricalcium phosphate(β-TCP)scaffolds incorporated with processed pyritum decoction(PPD)were fabricated using three-dimensional(3D)printing-assisted freeze-casting.The produced composite scaffolds were evaluated for their mechanical strength,physicochemical properties,biocompatibility,in vitro proangiogenic activity,and in vivo efficacy in repairing rabbit femoral defects.They not only demonstrated excellent physicochemical properties,enhanced mechanical strength,and good biosafety but also significantly promoted the proliferation,migration,and aggregation of pro-angiogenic human umbilical vein endothelial cells(HUVECs).In vivo studies revealed that all scaffold groups facilitated osteogenesis at the bone defect site,with theβ-TCP scaffolds loaded with PPD markedly enhancing the expression of neurogenic locus Notch homolog protein 1(Notch1),vascular endothelial growth factor(VEGF),bone morphogenetic protein-2(BMP-2),and osteopontin(OPN).Overall,the scaffolds developed in this study exhibited strong angiogenic and osteogenic capabilities both in vitro and in vivo.The incorporation of PPD notably promoted the angiogenic-osteogenic coupling,thereby accelerating bone repair,which suggests that PPD is a promising material for bone repair and that the PPD/β-TCP scaffolds hold great potential as a bone graft alternative. 展开更多
关键词 Bone defect Processed pyritum three-dimensional(3D)printing-assisted freeze-casting ANGIOGENESIS Bone regeneration VEGF-Notch1-BMP-2-OPN coupling
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Glasses-free three-dimensional laparoscopic systems in oncologic surgery:Innovation or equivalence?
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作者 Gustavo Eder González Alvarez Christian Ramírez Sánchez +3 位作者 Melissa Martínez Nieto Mario A Alarcón-Sánchez Juan JoséVarela-Hernández Sarah M LomelíMartínez 《World Journal of Gastrointestinal Surgery》 2025年第11期6-11,共6页
The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a rece... The development of minimally invasive surgery has transformed the management of gastrointestinal cancer.Notably,three-dimensional visualization systems have increased surgical precision.This editorial discusses a recent study by Shen and Zhang,which compared the clinical applications of naked-eye threedimensional laparoscopic systems vs traditional optical systems in radical surgery for gastric and colorectal cancer.Both systems appeared to yield comparable surgical and oncological outcomes in terms of safety parameters,operating times,and quality of lymph node dissection.However,the spectacle-free system’s technical and logistical limitations hindered its effects on the surgical team’s overall competency.This editorial examines the authors’findings within the broader context of the evolution of oncologic laparoscopy,discusses the relevance of the results in light of the current literature,and proposes future research directions focused on multicenter validation,comprehensive ergonomic analysis,and technological advancements aimed at enhancing intraoperative collaboration.As technology continues to evolve,clinical implementation of new methods must be supported by robust scientific evidence and standardized criteria,to ensure tangible improvements in efficiency,safety,and oncologic outcomes. 展开更多
关键词 Autostereoscopic three-dimensional technology Laparoscopic surgery three-dimensional laparoscopy Twodimensional laparoscopy Oncologic surgery
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Experimental and numerical investigation of the impact of helical coil targets on laser-driven proton and carbon accelerations
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作者 C.L.C.Lacoste E.Catrix +10 位作者 S.Vallières A.Hirsch-Passicos T.Guilberteau M.Lafargue J.Lopez I.Manek-Hönninger S.Fourmaux D.Raffestin E.d’Humières P.Antici M.Bardon 《Matter and Radiation at Extremes》 2025年第3期98-105,共8页
Laser-driven ion acceleration,as produced by interaction of a high-intensity laser with a target,is a growing field of interest.One of the current challenges is to enhance the acceleration process,i.e.,to increase the... Laser-driven ion acceleration,as produced by interaction of a high-intensity laser with a target,is a growing field of interest.One of the current challenges is to enhance the acceleration process,i.e.,to increase the produced ion energy and the ion number and to shape the energy distribution for future applications.In this paper,we investigate the effect of helical coil(HC)targets on the laser-matter interaction process using a 150 TW laser.We demonstrate that HC targets significantly enhance proton acceleration,improving energy bunching and beam focusing and increasing the cutoff energy.For the first time,we extend this analysis to carbon ions,revealing a marked reduction in the number of low-energy carbon ions and the potential for energy bunching and post-acceleration through an optimized HC design.Simulations using the particle-in-cell code SOPHIE confirm the experimental results,providing insights into the current propagation and ion synchronization mechanisms in HCs.Our findings suggest that HC targets can be optimized for multispecies ion acceleration. 展开更多
关键词 helical coil targets laser matter interaction ion energy distribution proton accelera carbon ion acceleration proton acceleration enhance acceleration processieto shape energy distribution
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Investigation into the degradation of 2,4,6-trichlorophenol utilizing a three-dimensional electrocatalytic reactor filled with fluorine-doped copper-carbon particle electrodes
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作者 Hongrui Zhang Wenyu Huang +4 位作者 Hainong Song Hanhui Yan Jia Zhang Fang Zhong Huilan Li 《Journal of Environmental Sciences》 2025年第9期701-719,共19页
The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated cata... The three-dimensional particle electrode system exhibits significant potential for application in the treatment of wastewater.Nonetheless,the advancement of effective granular electrodes characterized by elevated catalytic activity and minimal energy consumption continues to pose a significant challenge.In this research,Fluorine-doped copper-carbon(F/Cu-GAC)particle electrodes were effectively synthesized through an impregnationcalcination technique,utilizing granular activated carbon as the carrier and fluorinedoped modified copper oxides as the catalytic agents.The particle electrodes were subsequently utilized to promote the degradation of 2,4,6-trichlorophenol(2,4,6-TCP)in a threedimensional electrocatalytic reactor(3DER).The F/Cu-GAC particle electrodes were polarized under the action of electric field,which promoted the heterogeneous Fenton-like reaction in which H2O2 generated by two-electron oxygen reduction reaction(2e-ORR)of O_(2) was catalytically decomposed to·OH.The 3DER equipped with F/Cu-GAC particle electrodes showed 100%removal of 2,4,6-TCP and 79.24%removal of TOC with a specific energy consumption(EC)of approximately 0.019 kWh/g·COD after 2 h of operation.The F/Cu-GAC particle electrodes exhibited an overpotential of 0.38 V and an electrochemically active surface area(ECSA)of 715 cm^(2),as determined through linear sweep voltammetry(LSV)and cyclic voltammetry(CV)assessments.These findings suggest a high level of electrocatalytic performance.Furthermore,the catalytic mechanism of the 3DER equipped with F/Cu-GAC particle electrodes was elucidated through the application of X-ray photoelectron spectroscopy(XPS),electron spin resonance(ESR),and active species capture experiments.This investigation offers a novel approach for the effective degradation of 2,4,6-TCP. 展开更多
关键词 2 4 6-TRICHLOROPHENOL Heterogeneous Fenton-like process three-dimensional electrocatalytic reactor three-dimensional particle electrode system Fluorine-doped copper-carbon particle electrodes
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A Review of Three-Dimensional Research on Urban Recreation Space Based on CiteSpace
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作者 LIU Yongli 《Journal of Landscape Research》 2025年第1期30-34,共5页
In this study,CiteSpace software is used to carry out visual analysis on the three-dimensional research literature on urban recreation space from the perspective of compact city theory in the past 20 years,exploring t... In this study,CiteSpace software is used to carry out visual analysis on the three-dimensional research literature on urban recreation space from the perspective of compact city theory in the past 20 years,exploring the scientific development trend and research hotspots in this field.The results show that the number of published documents shows a fluctuating upward trend,and the significant growth rate reflects the role of policy orientation in promoting the concept of compact city.The co-occurrence analysis of keywords reveals the research hotspots of“compact city”,“recreation space”and“urban park”,while the emergence of new keywords such as“vertical city”and“spatial justice”indicates the new trend of recent research.The cluster analysis and timeline map further show the evolution of research themes,with“compact city”being the largest cluster and having rich connections with other themes such as“urban design”and“urban park”. 展开更多
关键词 Compact city Urban recreation space three-dimensional CITESPACE
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Resection of a ganglioneuroma encasing major blood vessels using three-dimensional laparoscopy combined with organ suspension:A case report
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作者 Guo-Zhen Wu Shen-Zhe Fang +1 位作者 Shi-An Yu Min Yu 《World Journal of Gastrointestinal Surgery》 2025年第8期467-475,共9页
BACKGROUND Ganglioneuroma is a rare,well-differentiated,slow-growing benign tumor of the peripheral nerves,with surgical resection being the only curative treatment.Surgical resection of ganglioneuromas encasing major... BACKGROUND Ganglioneuroma is a rare,well-differentiated,slow-growing benign tumor of the peripheral nerves,with surgical resection being the only curative treatment.Surgical resection of ganglioneuromas encasing major blood vessels remains a substantial clinical challenge.Traditionally,these cases often require open abdominal surgery or combined organ resections,and in some instances,the tumors are considered unresectable.Currently,no reports have described the resection of such tumors via laparoscopy.CASE SUMMARY A 35-year-old woman was admitted to our hospital after the incidental discovery of a retroperitoneal space-occupying lesion.Imaging revealed a mass with the celiac axis and superior mesenteric artery passing through it.A neurogenic tumor was suspected,with ganglioneuroma being the most likely diagnosis.Following comprehensive preoperative preparation,the retroperitoneal tumor was resected using a three-dimensional laparoscopy combined with an organ suspension technique.The surgical approach involved incising the tumor along the vascular axis and conducting meticulous,vascular-preserving tumor excision.The operation lasted approximately 458 minutes,with an estimated blood loss of 50 mL.The patient was discharged on the 8th postoperative day.A transient liver injury occurred after surgery but improved rapidly.After 11 months of postoperative follow-up,no complications or tumor recurrence were observed.CONCLUSION This case illustrates the feasibility of minimally invasive laparoscopic resection for retroperitoneal ganglioneuromas encasing major blood vessels. 展开更多
关键词 Ganglioneuromas Retroperitoneal three-dimensional laparoscopy Organ suspension Case report
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