Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Fa...Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.展开更多
The experiments were conducted for three consecutive years across 14 locations using 9 non-waxy proso millet genotypes and 16 locations using 7 waxy proso millet genotypes in China. The objectives of this study were t...The experiments were conducted for three consecutive years across 14 locations using 9 non-waxy proso millet genotypes and 16 locations using 7 waxy proso millet genotypes in China. The objectives of this study were to analyze yield stability and adaptability of proso millets and to evaluate the discrimination and representativeness of locations by analysis of vari- ance （ANOVA） and genotype and genotype by environment interaction （GGE） biplot methods. Grain yields of proso millet genotypes were significantly influenced by environment （E）, genotype （G） and their interaction （GxE） （P〈0.1%）. GxE inter- action effect was six times higher than G effect in non-waxy group and seven times in waxy group. N04-339 in non-waxy and Neimi 6 （NM6） in waxy showed higher grain yields and stability compared with other genotypes. Also, Neimi 9 （NM9, a non-waxy cultivar） and 90322-2-33 （a waxy cultivar） showed higher adaptability in 7 and in 11 locations, respectively. For non-waxy, Dalat, Inner Mongolia （E2） and Wuzhai, Shanxi （E5） were the best sites among all the locations for maximizing the variance among candidate cultivars, and Yanchi, Ningxia （El0） had the best representativeness. Wuzhai, Shanxi （e9） and Yanchi, Ningxia （e14） were the best representative locations, and Baicheng, Jilin （e2） was better discriminating location than others for waxy genotypes. Based on our results, El0 and e14 have enhanced efficiency and accuracy for non-waxy genotypes and waxy genotypes selection, respectively in national regional test of proso millet varieties.展开更多
Air pollution has seriously endangered human health and the natural ecosystem during the last decades.Air quality monitoring stations(AQMS)have played a critical role in providing valuable data sets for recording regi...Air pollution has seriously endangered human health and the natural ecosystem during the last decades.Air quality monitoring stations(AQMS)have played a critical role in providing valuable data sets for recording regional air pollutants.The spatial representativeness of AQMS is a critical parameter when choosing the location of stations and assessing effects on the population to long-term exposure to air pollution.In this paper,we proposed a methodological framework for assessing the spatial representativeness of the regional air quality monitoring network and applied it to ground-based PM_(2.5)observation in the mainland of China.Weighted multidimensional Euclidean distance between each pixel and the stations was used to determine the representativeness of the existing monitoring network.In addition,the K-means clustering method was adopted to improve the spatial representativeness of the existing AQMS.The results showed that there were obvious differences among the representative area of 1820 stations in the mainland of China.The monitoring stations could well represent the PM_(2.5)spatial distribution of the entire region,and the effectively represented area(i.e.the area where the Euclidean distance between the pixels and the stations was lower than the average value)accounted for 67.32%of the total area and covered 93.12%of the population.Forty additional stations were identified in the Northwest,North China,and Northeast regions,which could improve the spatial representativeness by 14.31%.展开更多
Objective:To compare the characteristics of suspected measles cases at the health facilities and to determine the representativeness of the data.Methods:We visited 25 hospitals in the Aniocha Local Government Area(LGA...Objective:To compare the characteristics of suspected measles cases at the health facilities and to determine the representativeness of the data.Methods:We visited 25 hospitals in the Aniocha Local Government Area(LGA) of Delta State,Nigeria,from which information on reportable diseases was collected.In particular,the suspected measles cases in their registries between January 1,2007,and June 30,2008,were reviewed.We compared the characteristics,including age,sex,location,and month of reporting,of the suspected cases with the LGA surveillance records.Results:In the LGA records,10%cases involved individuals older than 14 years, compared with 20%in the same age group in the health facility records.Based on geographic location,53%of the measles cases among the hospital records came from a single location,in contrast to only 30%of the cases among the LGA records.An analysis considering time revealed that 30%of the cases in the LGA records occurred in August 2007,whereas 20%of hospital cases were reported in February and May 2008 combined.Conclusions:The two record types differed considerably in all of the characteristics used in this comparison.展开更多
In late May,the city of Dunhuang,a key historical hub of Eastern and Western cultures in Northwest China's Gansu Province,basked in clear and refreshing weather under a brilliant blue sky.The rugged Mingsha Mounta...In late May,the city of Dunhuang,a key historical hub of Eastern and Western cultures in Northwest China's Gansu Province,basked in clear and refreshing weather under a brilliant blue sky.The rugged Mingsha Mountain,renowned for the musical sounds produced by wind-blown sands when the wind blows,stood in silent majesty.To the close north of the mountain's massive golden dunes stood the city's international convention centre,where some 400 vips from 60 countries host cultural exchanges and mutual learning.展开更多
Accurately assessing the relationship between tree growth and climatic factors is of great importance in dendrochronology.This study evaluated the consistency between alternative climate datasets(including station and...Accurately assessing the relationship between tree growth and climatic factors is of great importance in dendrochronology.This study evaluated the consistency between alternative climate datasets(including station and gridded data)and actual climate data(fixed-point observations near the sampling sites),in northeastern China’s warm temperate zone and analyzed differences in their correlations with tree-ring width index.The results were:(1)Gridded temperature data,as well as precipitation and relative humidity data from the Huailai meteorological station,was more consistent with the actual climate data;in contrast,gridded soil moisture content data showed significant discrepancies.(2)Horizontal distance had a greater impact on the representativeness of actual climate conditions than vertical elevation differences.(3)Differences in consistency between alternative and actual climate data also affected their correlations with tree-ring width indices.In some growing season months,correlation coefficients,both in magnitude and sign,differed significantly from those based on actual data.The selection of different alternative climate datasets can lead to biased results in assessing forest responses to climate change,which is detrimental to the management of forest ecosystems in harsh environments.Therefore,the scientific and rational selection of alternative climate data is essential for dendroecological and climatological research.展开更多
Successful ex situ conservation of plant populations requires a high degree of genetic representativeness.However,spatially biased sampling in ex situ conservation efforts may fail to capture all wild genetic clusters...Successful ex situ conservation of plant populations requires a high degree of genetic representativeness.However,spatially biased sampling in ex situ conservation efforts may fail to capture all wild genetic clusters for species with range-wide genetic structure.To investigate the extent of spatially biased sampling in living collections and the coverage of wild genetic clusters in plant populations under ex situ conservation worldwide,we combined a global synthesis of ex situ conservation efforts with a case study of an endangered riparian plant species,Myricaria laxiflora.Our analysis of ex situ conservation worldwide revealed that the majority(82.6%)of ex situ populations fail to cover all wild genetic clusters,largely due to spatially biased sampling with low geographic coverage.Our case study of M.laxiflora showed that genetic diversity differed between the ex situ and upstream populations,while it was comparable between ex situ populations and other wild populations.However,current ex situ populations did not cover all wild genetic clusters,as the upstream genetic cluster was previously uncollected.Our study suggests that the failure to cover all wild genetic clusters in ex situ populations is a widespread issue,and ex situ populations with high genetic diversity can also fail to cover all wild genetic clusters.In future ex situ conservation programs,both the importance of high genetic diversity and the high coverage of wild genetic clusters should be prioritized.展开更多
Hainan FTP will boost alignment with international rules in China’s opening up The Hainan Free Trade Port(FTP)represents a significant step forward in China’s pursuit of high-standard opening up and greater engageme...Hainan FTP will boost alignment with international rules in China’s opening up The Hainan Free Trade Port(FTP)represents a significant step forward in China’s pursuit of high-standard opening up and greater engagement in economic globalisation.Following years of exploration,the policy framework for the Hainan FTP has come into being,and the recent launch of island-wide special customs operations marks an important transition-from institutional design to full implementation.展开更多
The Hainan Free Trade Port’s implementation of special customs operations marks a significant stride in China’s institutional opening-up,spurring global trade and investment flows.THE Hainan Free Trade Port(FTP)repr...The Hainan Free Trade Port’s implementation of special customs operations marks a significant stride in China’s institutional opening-up,spurring global trade and investment flows.THE Hainan Free Trade Port(FTP)represents a significant step forward in China’s pursuit of high-standard opening-up and greater engagement in economic globalization.展开更多
Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has b...Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has been associated with the onset of various conditions,including acute respiratory infections,asthma,atopic dermatitis,and food allergies^([2]).Multiple factors,including age,sun exposure,adiposity,and genetics,influence vitamin D levels^([2,3]).Increasing attention has been directed toward understanding the environmental determinants that may influence vitamin D status.Given the potential of metallic pollutants to disrupt endocrine function and their ubiquity in the environment,investigating the effects of metal exposure on human vitamin D status,particularly in vulnerable populations,is imperative.展开更多
Bulked-segregant analysis coupled with next-generation sequencing(BSA-seq) has emerged as an efficient tool for genetic mapping of single genes or major quantitative trait loci controlling(agronomic) traits of interes...Bulked-segregant analysis coupled with next-generation sequencing(BSA-seq) has emerged as an efficient tool for genetic mapping of single genes or major quantitative trait loci controlling(agronomic) traits of interest. However, such a mapping-by-sequencing approach usually relies on deep sequencing and advanced statistical methods. Application of BSA-Seq based on construction of reduced-representation libraries and allele frequency analysis permitted anchoring the barley pale-green(pg) gene on chromosome 3 HL. With further marker-assisted validation, pg was mapped to a 3.9 Mb physical-map interval. In the pg mutant a complete deletion of chlorophyllide a oxygenase(HvCAO) gene was identified.Because the product of this gene converts Chl a to Chl b, the pg mutant is deficient in Chl b.An independent Chl b-less mutant line M4437_2 carried a nonsynonymous substitution(F263 L) in the C domain of HvCAO. The study demonstrates an optimized pooling strategy for fast mapping of agronomically important genes using a segregating population.展开更多
基金supported by the National Natural Science Foundation of China(82341245,82371491)the Chinese Central Government(Key Project of Public Health Program)the National Key Research and Development Program of China(2018YFC1311706,2018YFC1311702)。
文摘Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.
基金funded by the National Key Technologies R&D Program of China during the 12th Five-Year Plan period (2014BAD07B03)the National Natural Science Foundation of China (31371529)+2 种基金the Postdoctoral Science Foundation of Heilongjiang Province, China (LBH-Z14177)the project of Education Department in Heilongjiang Province, China (12541599)the China Agricultural Research System (CARS07-13.5-A9)
文摘The experiments were conducted for three consecutive years across 14 locations using 9 non-waxy proso millet genotypes and 16 locations using 7 waxy proso millet genotypes in China. The objectives of this study were to analyze yield stability and adaptability of proso millets and to evaluate the discrimination and representativeness of locations by analysis of vari- ance （ANOVA） and genotype and genotype by environment interaction （GGE） biplot methods. Grain yields of proso millet genotypes were significantly influenced by environment （E）, genotype （G） and their interaction （GxE） （P〈0.1%）. GxE inter- action effect was six times higher than G effect in non-waxy group and seven times in waxy group. N04-339 in non-waxy and Neimi 6 （NM6） in waxy showed higher grain yields and stability compared with other genotypes. Also, Neimi 9 （NM9, a non-waxy cultivar） and 90322-2-33 （a waxy cultivar） showed higher adaptability in 7 and in 11 locations, respectively. For non-waxy, Dalat, Inner Mongolia （E2） and Wuzhai, Shanxi （E5） were the best sites among all the locations for maximizing the variance among candidate cultivars, and Yanchi, Ningxia （El0） had the best representativeness. Wuzhai, Shanxi （e9） and Yanchi, Ningxia （e14） were the best representative locations, and Baicheng, Jilin （e2） was better discriminating location than others for waxy genotypes. Based on our results, El0 and e14 have enhanced efficiency and accuracy for non-waxy genotypes and waxy genotypes selection, respectively in national regional test of proso millet varieties.
基金funded by the National Natural Science Foundation of China (41977399)the National Key Research and Development Program (2017YFC0505800)
文摘Air pollution has seriously endangered human health and the natural ecosystem during the last decades.Air quality monitoring stations(AQMS)have played a critical role in providing valuable data sets for recording regional air pollutants.The spatial representativeness of AQMS is a critical parameter when choosing the location of stations and assessing effects on the population to long-term exposure to air pollution.In this paper,we proposed a methodological framework for assessing the spatial representativeness of the regional air quality monitoring network and applied it to ground-based PM_(2.5)observation in the mainland of China.Weighted multidimensional Euclidean distance between each pixel and the stations was used to determine the representativeness of the existing monitoring network.In addition,the K-means clustering method was adopted to improve the spatial representativeness of the existing AQMS.The results showed that there were obvious differences among the representative area of 1820 stations in the mainland of China.The monitoring stations could well represent the PM_(2.5)spatial distribution of the entire region,and the effectively represented area(i.e.the area where the Euclidean distance between the pixels and the stations was lower than the average value)accounted for 67.32%of the total area and covered 93.12%of the population.Forty additional stations were identified in the Northwest,North China,and Northeast regions,which could improve the spatial representativeness by 14.31%.
文摘Objective:To compare the characteristics of suspected measles cases at the health facilities and to determine the representativeness of the data.Methods:We visited 25 hospitals in the Aniocha Local Government Area(LGA) of Delta State,Nigeria,from which information on reportable diseases was collected.In particular,the suspected measles cases in their registries between January 1,2007,and June 30,2008,were reviewed.We compared the characteristics,including age,sex,location,and month of reporting,of the suspected cases with the LGA surveillance records.Results:In the LGA records,10%cases involved individuals older than 14 years, compared with 20%in the same age group in the health facility records.Based on geographic location,53%of the measles cases among the hospital records came from a single location,in contrast to only 30%of the cases among the LGA records.An analysis considering time revealed that 30%of the cases in the LGA records occurred in August 2007,whereas 20%of hospital cases were reported in February and May 2008 combined.Conclusions:The two record types differed considerably in all of the characteristics used in this comparison.
文摘In late May,the city of Dunhuang,a key historical hub of Eastern and Western cultures in Northwest China's Gansu Province,basked in clear and refreshing weather under a brilliant blue sky.The rugged Mingsha Mountain,renowned for the musical sounds produced by wind-blown sands when the wind blows,stood in silent majesty.To the close north of the mountain's massive golden dunes stood the city's international convention centre,where some 400 vips from 60 countries host cultural exchanges and mutual learning.
基金supported by the International Partnership program of the Chinese Academy of Sciences(170GJHZ2023074GC)National Natural Science Foundation of China(42425706 and 42488201)+1 种基金National Key Research and Development Program of China(2024YFF0807902)Beijing Natural Science Foundation(8242041),and China Postdoctoral Science Foundation(2025M770353).
文摘Accurately assessing the relationship between tree growth and climatic factors is of great importance in dendrochronology.This study evaluated the consistency between alternative climate datasets(including station and gridded data)and actual climate data(fixed-point observations near the sampling sites),in northeastern China’s warm temperate zone and analyzed differences in their correlations with tree-ring width index.The results were:(1)Gridded temperature data,as well as precipitation and relative humidity data from the Huailai meteorological station,was more consistent with the actual climate data;in contrast,gridded soil moisture content data showed significant discrepancies.(2)Horizontal distance had a greater impact on the representativeness of actual climate conditions than vertical elevation differences.(3)Differences in consistency between alternative and actual climate data also affected their correlations with tree-ring width indices.In some growing season months,correlation coefficients,both in magnitude and sign,differed significantly from those based on actual data.The selection of different alternative climate datasets can lead to biased results in assessing forest responses to climate change,which is detrimental to the management of forest ecosystems in harsh environments.Therefore,the scientific and rational selection of alternative climate data is essential for dendroecological and climatological research.
基金supported by National Key Research and Development Program of China(2024YFF1307400)Hubei Provincial Natural Science Foundation and Three Gorges Innovation Development Joint Fund(Grant No.2023AFD195)China Three Gorges Corporation(NBZZ202300130).
文摘Successful ex situ conservation of plant populations requires a high degree of genetic representativeness.However,spatially biased sampling in ex situ conservation efforts may fail to capture all wild genetic clusters for species with range-wide genetic structure.To investigate the extent of spatially biased sampling in living collections and the coverage of wild genetic clusters in plant populations under ex situ conservation worldwide,we combined a global synthesis of ex situ conservation efforts with a case study of an endangered riparian plant species,Myricaria laxiflora.Our analysis of ex situ conservation worldwide revealed that the majority(82.6%)of ex situ populations fail to cover all wild genetic clusters,largely due to spatially biased sampling with low geographic coverage.Our case study of M.laxiflora showed that genetic diversity differed between the ex situ and upstream populations,while it was comparable between ex situ populations and other wild populations.However,current ex situ populations did not cover all wild genetic clusters,as the upstream genetic cluster was previously uncollected.Our study suggests that the failure to cover all wild genetic clusters in ex situ populations is a widespread issue,and ex situ populations with high genetic diversity can also fail to cover all wild genetic clusters.In future ex situ conservation programs,both the importance of high genetic diversity and the high coverage of wild genetic clusters should be prioritized.
文摘Hainan FTP will boost alignment with international rules in China’s opening up The Hainan Free Trade Port(FTP)represents a significant step forward in China’s pursuit of high-standard opening up and greater engagement in economic globalisation.Following years of exploration,the policy framework for the Hainan FTP has come into being,and the recent launch of island-wide special customs operations marks an important transition-from institutional design to full implementation.
文摘The Hainan Free Trade Port’s implementation of special customs operations marks a significant stride in China’s institutional opening-up,spurring global trade and investment flows.THE Hainan Free Trade Port(FTP)represents a significant step forward in China’s pursuit of high-standard opening-up and greater engagement in economic globalization.
基金supported by grants from the National Natural Science Foundation of China(G.F.Wang,grant number 82204071)(P.Y.Su,grant numbers 81874268 and 82473655)the Research Funds of the Center for Big Data and Population Health of IHM(P.Y.Su,No.JKS2023016)Anhui Provincial Health Commission Scientific Research Project(Y.Zhou,No.AHWJ2023A30027)。
文摘Vitamin D deficiency(VDD)represents a significant nutritional concern among children and adolescents.The estimated prevalence of VDD in China is 46.8%in this population^([1]).VDD during childhood and adolescence has been associated with the onset of various conditions,including acute respiratory infections,asthma,atopic dermatitis,and food allergies^([2]).Multiple factors,including age,sun exposure,adiposity,and genetics,influence vitamin D levels^([2,3]).Increasing attention has been directed toward understanding the environmental determinants that may influence vitamin D status.Given the potential of metallic pollutants to disrupt endocrine function and their ubiquity in the environment,investigating the effects of metal exposure on human vitamin D status,particularly in vulnerable populations,is imperative.
基金supported by the Young Elite Scientists Sponsorship Program by China Association for Science and Technology (2015QNRC001)the National Natural Science Foundation of China (31370032)+1 种基金the China Agriculture Research System (CARS-05)the Agricultural Science and Technology Innovation Program
文摘Bulked-segregant analysis coupled with next-generation sequencing(BSA-seq) has emerged as an efficient tool for genetic mapping of single genes or major quantitative trait loci controlling(agronomic) traits of interest. However, such a mapping-by-sequencing approach usually relies on deep sequencing and advanced statistical methods. Application of BSA-Seq based on construction of reduced-representation libraries and allele frequency analysis permitted anchoring the barley pale-green(pg) gene on chromosome 3 HL. With further marker-assisted validation, pg was mapped to a 3.9 Mb physical-map interval. In the pg mutant a complete deletion of chlorophyllide a oxygenase(HvCAO) gene was identified.Because the product of this gene converts Chl a to Chl b, the pg mutant is deficient in Chl b.An independent Chl b-less mutant line M4437_2 carried a nonsynonymous substitution(F263 L) in the C domain of HvCAO. The study demonstrates an optimized pooling strategy for fast mapping of agronomically important genes using a segregating population.
