With the reduction of sequencing costs,optimization of algorithms,and improvement of multi-omics integration capabilities,transcriptomics,as a core technology for analyzing gene expression dynamics and discovering key...With the reduction of sequencing costs,optimization of algorithms,and improvement of multi-omics integration capabilities,transcriptomics,as a core technology for analyzing gene expression dynamics and discovering key functional molecules,has shown great potential in the field of disease prevention and control[1,2].The multi-continental transcriptomics study of tick-borne poxvirus not only provides a new perspective for understanding the evolution and transmission of vector-mediated viruses,but also reflects the trend of transcriptomics research and highlights its key role in disease prevention and control[3].展开更多
The breakthrough of key core technology is a theoretical and practical strategic issue to realize the rise of the country.This paper analyzes the concept of key core technology and its breakthrough and analyzes its ch...The breakthrough of key core technology is a theoretical and practical strategic issue to realize the rise of the country.This paper analyzes the concept of key core technology and its breakthrough and analyzes its characteristics.Based on the perspective of participants,this paper summarizes the influencing factors of key core technology breakthroughs in enterprises:internal and external enterprises,universities and scientific research institutions,and government.This paper expands the relevant research on key core technology breakthroughs and provides inspiration for enterprises to carry out key core technology research and breakthrough practices.展开更多
Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman...Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman of Shandong Huasheng Textile Group Co.,Ltd.and leader of Hong Kong Huasheng Group,has the boots-on-the-ground confidence when discussing technological breakthroughs.展开更多
It is learned from the 2013 Summit Forum on Strategic Development of Coal-to-Natural Gas in China that the China Sedin Engineering Company,Ltd.has developed with independent intellectual property rights two experiment...It is learned from the 2013 Summit Forum on Strategic Development of Coal-to-Natural Gas in China that the China Sedin Engineering Company,Ltd.has developed with independent intellectual property rights two experimental furnaces for pressurized gasification of crushed coal,5 m展开更多
Separation technology of rare earth elements （REEs）, as the critical step in the separation process, had long been fraught with technical difficulty. A research project conducted by Baotou Shibo Rare Earth Extracti...Separation technology of rare earth elements （REEs）, as the critical step in the separation process, had long been fraught with technical difficulty. A research project conducted by Baotou Shibo Rare Earth Extraction ＆ Equipment Co. Ltd., Baotou REE Research Institute, and Baotou Steel ＆ REE Group Hi-Tech Co. Ltd （Inner Mongolia）, has successfully solved the problem using a centrifugal extractor and advanced techniques to achieve a key breakthrough.展开更多
Continental shale oil is an important strategic supplement to the sustainable development of petroleum industry in China.Based on the thermal maturity of organic matter,most shale oil in China is mediumhigh or medium-...Continental shale oil is an important strategic supplement to the sustainable development of petroleum industry in China.Based on the thermal maturity of organic matter,most shale oil in China is mediumhigh or medium-low mature oil with relatively high density that is usually stored in thin layers and difficult to extract due to strong fluid flow resistance.Most petroliferous basins in China host shale oil but the abundance and distribution are not favorable for operators looking for a commercial exploitation.This study systematically investigates the recent progress of shale oil exploration and development in China.The result shows that the country is facing the following challenges while trying to explore its shale oil resources:complex geological conditions;a lack of established effective development mode;high development cost;and an absence of substantial breakthroughs in key technologies.Given these,the study suggests from research and policy-making perspectives to strengthen the research on basic theories and key technologies,establish demonstration zones for development of different types of shale oil,pursue breakthroughs in a stepwise approach,innovate the management mode to reduce the development cost,set shale oil as an independent mineral type,and give special policy incentives.展开更多
The steel industry has come a long way in increasing its energy efficiency.In Europe the carbon intensity of steelmaking over the last 40 years was decreased by a factor 2.The potential for further improvements is now...The steel industry has come a long way in increasing its energy efficiency.In Europe the carbon intensity of steelmaking over the last 40 years was decreased by a factor 2.The potential for further improvements is now becoming less obvious as blast furnace operations are approaching the thermodynamical lower limit of hot metal production.To take on the climate change challenge and be able to respond to the expectation for strong reduction of carbon emissions,ArcelorMittal(AM) has developed a two step approach: (1) In a first instance given the modest remaining potential for incremental improvements precise benchmark tools were developed.This allowed identifying the top runners and determining the remaining potential for improvement.Plans were developed to bridge the gap with this achievable performance.In total a plan was devised with more than 400 identified actions throughout the group.This action plan will allow achieving a further 8% increase of CO_2 efficiency by 2020. (2 ) Secondly,already in 2002 AM engaged in the development of breakthrough technologies to further drastically reduce the carbon intensity of steelmaking.After screening a large number of candidates a few were selected for further development.A first breakthrough technology which is the most advanced stage of development can be applied to existing blast furnace and is reaching maturity and a demonstration on industrial scale of this technology is under preparation.In itself this technology will decrease the dependency on carbon as well as increase the productivity of the original blast furnaces.Real big gains can be made if this technology can be combined with underground carbon storage. In the AM roadmap the impact of raw materials(DRI,scrap) was excluded.In the longer run however the attention will have to turn to the overall footprint of materials and the long term consequences of the choice of materials.Increasing the recovery while preserving the quality of used steel products will leverage greatly the efforts done in the production of primary and secondary steel and power.展开更多
From 2019 to 2024,China's new energy vehicles(NEVs)industry has achieved remarkable accomplishments in areas including policy support,market scale,technological advancements,industrial chain development,and intern...From 2019 to 2024,China's new energy vehicles(NEVs)industry has achieved remarkable accomplishments in areas including policy support,market scale,technological advancements,industrial chain development,and internationalization.In the future,with further technological breakthroughs and continuous market expansion,China's NEVs industry is poised to play an even more significant role on the global stage.展开更多
advancements in first-in-class therapies and breakthrough technologies.The United States has maintained its leadership in first-in-class therapies and breakthrough technologies,driven by advanced regulatory pathways,s...advancements in first-in-class therapies and breakthrough technologies.The United States has maintained its leadership in first-in-class therapies and breakthrough technologies,driven by advanced regulatory pathways,significant multinational corporation investments,a robust Research and Development(R&D)workforce,and continuous technological innovation.Additionally,global impact of the Food and Drug Administration(FDA)is further amplified through collaborations like Project Orbis,which facilitates simultaneous reviews of cancer treatments by multiple regulatory authorities worldwide.Europe,while historically strong,faces growing challenges in maintaining its competitive edge,particularly due to protracted regulatory timelines and complex coordination among its member states.In this competitive global environment,China has rapidly transformed from a generics-dominated market to a key player in innovative drug development.This article reviews China’s progress in innovative drug R&D from 2019 to 2023,emphasizing regulatory modernization,clinical trial advancements,and the emergence of novel therapies.By comparing China’s developments with above global counterparts,this review highlights the country’s achievements in regulatory efficiency,clinical trial progress,and the development of innovative therapies such as biologics and cell and gene therapies.展开更多
Seen as a solution to global net zero goals,as well as an efficient and cheap way to heat and cool buildings,heat pumps are expected to be a crucial technology.But as uptake is slower than expected,the industry says m...Seen as a solution to global net zero goals,as well as an efficient and cheap way to heat and cool buildings,heat pumps are expected to be a crucial technology.But as uptake is slower than expected,the industry says more government support is needed,as well as technological breakthroughs.展开更多
文摘With the reduction of sequencing costs,optimization of algorithms,and improvement of multi-omics integration capabilities,transcriptomics,as a core technology for analyzing gene expression dynamics and discovering key functional molecules,has shown great potential in the field of disease prevention and control[1,2].The multi-continental transcriptomics study of tick-borne poxvirus not only provides a new perspective for understanding the evolution and transmission of vector-mediated viruses,but also reflects the trend of transcriptomics research and highlights its key role in disease prevention and control[3].
文摘The breakthrough of key core technology is a theoretical and practical strategic issue to realize the rise of the country.This paper analyzes the concept of key core technology and its breakthrough and analyzes its characteristics.Based on the perspective of participants,this paper summarizes the influencing factors of key core technology breakthroughs in enterprises:internal and external enterprises,universities and scientific research institutions,and government.This paper expands the relevant research on key core technology breakthroughs and provides inspiration for enterprises to carry out key core technology research and breakthrough practices.
文摘Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman of Shandong Huasheng Textile Group Co.,Ltd.and leader of Hong Kong Huasheng Group,has the boots-on-the-ground confidence when discussing technological breakthroughs.
文摘It is learned from the 2013 Summit Forum on Strategic Development of Coal-to-Natural Gas in China that the China Sedin Engineering Company,Ltd.has developed with independent intellectual property rights two experimental furnaces for pressurized gasification of crushed coal,5 m
文摘Separation technology of rare earth elements （REEs）, as the critical step in the separation process, had long been fraught with technical difficulty. A research project conducted by Baotou Shibo Rare Earth Extraction ＆ Equipment Co. Ltd., Baotou REE Research Institute, and Baotou Steel ＆ REE Group Hi-Tech Co. Ltd （Inner Mongolia）, has successfully solved the problem using a centrifugal extractor and advanced techniques to achieve a key breakthrough.
文摘Continental shale oil is an important strategic supplement to the sustainable development of petroleum industry in China.Based on the thermal maturity of organic matter,most shale oil in China is mediumhigh or medium-low mature oil with relatively high density that is usually stored in thin layers and difficult to extract due to strong fluid flow resistance.Most petroliferous basins in China host shale oil but the abundance and distribution are not favorable for operators looking for a commercial exploitation.This study systematically investigates the recent progress of shale oil exploration and development in China.The result shows that the country is facing the following challenges while trying to explore its shale oil resources:complex geological conditions;a lack of established effective development mode;high development cost;and an absence of substantial breakthroughs in key technologies.Given these,the study suggests from research and policy-making perspectives to strengthen the research on basic theories and key technologies,establish demonstration zones for development of different types of shale oil,pursue breakthroughs in a stepwise approach,innovate the management mode to reduce the development cost,set shale oil as an independent mineral type,and give special policy incentives.
文摘The steel industry has come a long way in increasing its energy efficiency.In Europe the carbon intensity of steelmaking over the last 40 years was decreased by a factor 2.The potential for further improvements is now becoming less obvious as blast furnace operations are approaching the thermodynamical lower limit of hot metal production.To take on the climate change challenge and be able to respond to the expectation for strong reduction of carbon emissions,ArcelorMittal(AM) has developed a two step approach: (1) In a first instance given the modest remaining potential for incremental improvements precise benchmark tools were developed.This allowed identifying the top runners and determining the remaining potential for improvement.Plans were developed to bridge the gap with this achievable performance.In total a plan was devised with more than 400 identified actions throughout the group.This action plan will allow achieving a further 8% increase of CO_2 efficiency by 2020. (2 ) Secondly,already in 2002 AM engaged in the development of breakthrough technologies to further drastically reduce the carbon intensity of steelmaking.After screening a large number of candidates a few were selected for further development.A first breakthrough technology which is the most advanced stage of development can be applied to existing blast furnace and is reaching maturity and a demonstration on industrial scale of this technology is under preparation.In itself this technology will decrease the dependency on carbon as well as increase the productivity of the original blast furnaces.Real big gains can be made if this technology can be combined with underground carbon storage. In the AM roadmap the impact of raw materials(DRI,scrap) was excluded.In the longer run however the attention will have to turn to the overall footprint of materials and the long term consequences of the choice of materials.Increasing the recovery while preserving the quality of used steel products will leverage greatly the efforts done in the production of primary and secondary steel and power.
文摘From 2019 to 2024,China's new energy vehicles(NEVs)industry has achieved remarkable accomplishments in areas including policy support,market scale,technological advancements,industrial chain development,and internationalization.In the future,with further technological breakthroughs and continuous market expansion,China's NEVs industry is poised to play an even more significant role on the global stage.
基金supported by the Key Project of the National Medical Products Administration for the Construction of the Drug Regulatory Science System (RS2024Z003).
文摘advancements in first-in-class therapies and breakthrough technologies.The United States has maintained its leadership in first-in-class therapies and breakthrough technologies,driven by advanced regulatory pathways,significant multinational corporation investments,a robust Research and Development(R&D)workforce,and continuous technological innovation.Additionally,global impact of the Food and Drug Administration(FDA)is further amplified through collaborations like Project Orbis,which facilitates simultaneous reviews of cancer treatments by multiple regulatory authorities worldwide.Europe,while historically strong,faces growing challenges in maintaining its competitive edge,particularly due to protracted regulatory timelines and complex coordination among its member states.In this competitive global environment,China has rapidly transformed from a generics-dominated market to a key player in innovative drug development.This article reviews China’s progress in innovative drug R&D from 2019 to 2023,emphasizing regulatory modernization,clinical trial advancements,and the emergence of novel therapies.By comparing China’s developments with above global counterparts,this review highlights the country’s achievements in regulatory efficiency,clinical trial progress,and the development of innovative therapies such as biologics and cell and gene therapies.
文摘Seen as a solution to global net zero goals,as well as an efficient and cheap way to heat and cool buildings,heat pumps are expected to be a crucial technology.But as uptake is slower than expected,the industry says more government support is needed,as well as technological breakthroughs.
