Objective: to explore the cause, mechanism and solution of nervous system damage caused by amoxicillin and clavulanate potassium in an elderly patient through clinical pharmacists participation in case analysis. Metho...Objective: to explore the cause, mechanism and solution of nervous system damage caused by amoxicillin and clavulanate potassium in an elderly patient through clinical pharmacists participation in case analysis. Methods: by sorting out the relevant data, and analyzing the patients condition characteristics, clinical medication and other comprehensive analysis. Results: the adverse reactions of this patient were generally caused by injection of amoxicillin and clavulanate potassium. Conclusion: clinical pharmacists must put adverse drug reactions in an important position for prevention and control, and prepare a scientific and reasonable drug treatment plan under the guidance of clinicians to ensure the safety and effectiveness of patients clinical medication, and maximize the professional value of clinical pharmacists.展开更多
The active Lamb wave and piezoelectric transducer(PZT)-based structural health monitoring(SHM)technology is a kind of efficient approach to estimate the health state of aircraft structure.In practical applications,PZT...The active Lamb wave and piezoelectric transducer(PZT)-based structural health monitoring(SHM)technology is a kind of efficient approach to estimate the health state of aircraft structure.In practical applications,PZT networks are needed to monitor large scale structures.Scanning many of the different PZT actuator-sensor channels within these PZT networks to achieve on-line SHM task is important.Based on a peripheral component interconnect extensions for instrumentation(PXI)platform,an active Lamb wave and PZT network-based integrated multi-channel scanning system(PXI-ISS)is developed for the purpose of practical applications of SHM,which is compact and portable,and can scan large numbers of actuator-sensor channels and perform damage assessing automatically.A PXI-based 4 channels gain-programmable charge amplifier,an external scanning module with 276 actuator-sensor channels and integrated SHM software are proposed and discussed in detail.The experimental research on a carbon fiber composite wing box of an unmanned aerial vehicle(UAV)for verifying the functions of the PXI-ISS is mainly discussed,including the design of PZTs layer,the method of excitation frequency selection,functional test of damage imaging,stability test of the PXI-ISS,and the loading effect on signals.The experimental results have verified the stability and damage functions of this system.展开更多
Transorbital craniocerebral injury is a relatively rare type of penetrating head injury that poses a significant threat to the ocular and cerebral structures.^([1])The clinical prognosis of transorbital craniocerebral...Transorbital craniocerebral injury is a relatively rare type of penetrating head injury that poses a significant threat to the ocular and cerebral structures.^([1])The clinical prognosis of transorbital craniocerebral injury is closely related to the size,shape,speed,nature,and trajectory of the foreign object,as well as the incidence of central nervous system damage and secondary complications.The foreign objects reported to have caused these injuries are categorized into wooden items,metallic items,^([2-8])and other materials,which penetrate the intracranial region via fi ve major pathways,including the orbital roof (OR),superior orbital fissure (SOF),inferior orbital fissure(IOF),optic canal (OC),and sphenoid wing.Herein,we present eight cases of transorbital craniocerebral injury caused by an unusual metallic foreign body.展开更多
The data-driven methods extract the feature information from data to build system models, which enable estimation and identification of the systems and can be utilized for prognosis and health management(PHM). However...The data-driven methods extract the feature information from data to build system models, which enable estimation and identification of the systems and can be utilized for prognosis and health management(PHM). However, most data-driven models are still black-box models that cannot be interpreted. In this study, we use the neural ordinary differential equations(ODEs), especially the inherent computational relationships of a system added to the loss function calculation, to approximate the governing equations. In addition, a new strategy for identifying the local parameters of the system is investigated, which can be utilized for system parameter identification and damage detection. The numerical and experimental examples presented in the paper demonstrate that the strategy has high accuracy and good local parameter identification. Moreover, the proposed method has the advantage of being interpretable. It can directly approximate the underlying governing dynamics and be a worthwhile strategy for system identification and PHM.展开更多
文摘Objective: to explore the cause, mechanism and solution of nervous system damage caused by amoxicillin and clavulanate potassium in an elderly patient through clinical pharmacists participation in case analysis. Methods: by sorting out the relevant data, and analyzing the patients condition characteristics, clinical medication and other comprehensive analysis. Results: the adverse reactions of this patient were generally caused by injection of amoxicillin and clavulanate potassium. Conclusion: clinical pharmacists must put adverse drug reactions in an important position for prevention and control, and prepare a scientific and reasonable drug treatment plan under the guidance of clinicians to ensure the safety and effectiveness of patients clinical medication, and maximize the professional value of clinical pharmacists.
基金National High-tech Research and Development Program of China(2007AA03Z117)National Natural Science Foundation of China(50830201)Graduate Education Innovation Project of Nanjing University of Aeronautics and Astronautics of China(BCXJ09-01).
文摘The active Lamb wave and piezoelectric transducer(PZT)-based structural health monitoring(SHM)technology is a kind of efficient approach to estimate the health state of aircraft structure.In practical applications,PZT networks are needed to monitor large scale structures.Scanning many of the different PZT actuator-sensor channels within these PZT networks to achieve on-line SHM task is important.Based on a peripheral component interconnect extensions for instrumentation(PXI)platform,an active Lamb wave and PZT network-based integrated multi-channel scanning system(PXI-ISS)is developed for the purpose of practical applications of SHM,which is compact and portable,and can scan large numbers of actuator-sensor channels and perform damage assessing automatically.A PXI-based 4 channels gain-programmable charge amplifier,an external scanning module with 276 actuator-sensor channels and integrated SHM software are proposed and discussed in detail.The experimental research on a carbon fiber composite wing box of an unmanned aerial vehicle(UAV)for verifying the functions of the PXI-ISS is mainly discussed,including the design of PZTs layer,the method of excitation frequency selection,functional test of damage imaging,stability test of the PXI-ISS,and the loading effect on signals.The experimental results have verified the stability and damage functions of this system.
文摘Transorbital craniocerebral injury is a relatively rare type of penetrating head injury that poses a significant threat to the ocular and cerebral structures.^([1])The clinical prognosis of transorbital craniocerebral injury is closely related to the size,shape,speed,nature,and trajectory of the foreign object,as well as the incidence of central nervous system damage and secondary complications.The foreign objects reported to have caused these injuries are categorized into wooden items,metallic items,^([2-8])and other materials,which penetrate the intracranial region via fi ve major pathways,including the orbital roof (OR),superior orbital fissure (SOF),inferior orbital fissure(IOF),optic canal (OC),and sphenoid wing.Herein,we present eight cases of transorbital craniocerebral injury caused by an unusual metallic foreign body.
基金Project supported by the National Natural Science Foundation of China (Nos. 12132010 and12021002)the Natural Science Foundation of Tianjin of China (No. 19JCZDJC38800)。
文摘The data-driven methods extract the feature information from data to build system models, which enable estimation and identification of the systems and can be utilized for prognosis and health management(PHM). However, most data-driven models are still black-box models that cannot be interpreted. In this study, we use the neural ordinary differential equations(ODEs), especially the inherent computational relationships of a system added to the loss function calculation, to approximate the governing equations. In addition, a new strategy for identifying the local parameters of the system is investigated, which can be utilized for system parameter identification and damage detection. The numerical and experimental examples presented in the paper demonstrate that the strategy has high accuracy and good local parameter identification. Moreover, the proposed method has the advantage of being interpretable. It can directly approximate the underlying governing dynamics and be a worthwhile strategy for system identification and PHM.
