A pure culture using benzene as sole carbon and energy sources was isolated by screening procedure from gasoline contaminated soil.The analysis of the 16S rDNA gene sequence,morphological and physiological characteris...A pure culture using benzene as sole carbon and energy sources was isolated by screening procedure from gasoline contaminated soil.The analysis of the 16S rDNA gene sequence,morphological and physiological characteristics showed that the isolated strain was a member of genus Bacillus cereus.The biodegradation performance of benzene by B.cereus was evaluated,and the results showed that benzene could be efficiently biodegraded when the initial benzene concentration was below 150 mg/L.The metabolites of anaerobic nitrate-dependent benzene oxidation by strain B.cereus were identified as phenol and benzoate.The results of substrate interaction between binary combinations for benzene,phenol and benzoate showed that the simultaneous presence of benzene stimulated the degradation of benzoate,whereas the addition of benzene inhibited the degradation of phenol.Benzene degradation by B.cereus was enhanced by the addition of phenol and benzoate,the enhanced effects were more pronounced at higher concentration.To our knowledge,this is the first report that the isolated bacterial culture of B.cereus can efficiently degraded benzene under nitrate reducing conditions.展开更多
A recent study by Li et al.[1]was published in Nature and proposed the crucial roles of lactylation in regulating innate immunity.Alanyl-tRNA synthetase 1(AARS1)and AARS2,the intracellular L-lactate sensors,were demon...A recent study by Li et al.[1]was published in Nature and proposed the crucial roles of lactylation in regulating innate immunity.Alanyl-tRNA synthetase 1(AARS1)and AARS2,the intracellular L-lactate sensors,were demonstrated to directly conjugate L-lactate to a lysine residue of substrate proteins.AARS2interacts with cGAS and mediates its lactylation,dampening cGAS-mediated innate antiviral response.展开更多
The synthesis of high-quality ultrathin overlayers is critically dependent on the surface structure of substrates,especially involving the overlayer–substrate interaction.By using in situ surface measurements,we demo...The synthesis of high-quality ultrathin overlayers is critically dependent on the surface structure of substrates,especially involving the overlayer–substrate interaction.By using in situ surface measurements,we demonstrate that the overlayer–substrate interaction can be tuned by doping near-surface Ar nanobubbles.The interfacial coupling strength significantly decreases with near-surface Ar nanobubbles,accompanying by an“anisotropic to isotropic”growth transformation.On the substrate containing near-surface Ar,the growth front crosses entire surface atomic steps in both uphill and downhill directions with no difference,and thus,the morphology of the two-dimensional(2D)overlayer exhibits a round-shape.Especially,the round-shaped 2D overlayers coalesce seamlessly with a growth acceleration in the approaching direction,which is barely observed in the synthesis of 2D materials.This can be attributed to the immigration lifetime and diffusion rate of growth species,which depends on the overlayer–substrate interaction and the surface catalysis.Furthermore,the“round to hexagon”morphological transition is achieved by etching-regrowth,revealing the inherent growth kinetics under quasi-freestanding conditions.These findings provide a novel promising way to modulate the growth,coalescence,and etching dynamics of 2D materials on solid surfaces by adjusting the strength of overlayer–substrate interaction,which contributes to optimization of large-scale production of 2D material crystals.展开更多
基金supported by the National Natural Science Foundation of China (No. 40873076,40773055)the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry (No.2008890)
文摘A pure culture using benzene as sole carbon and energy sources was isolated by screening procedure from gasoline contaminated soil.The analysis of the 16S rDNA gene sequence,morphological and physiological characteristics showed that the isolated strain was a member of genus Bacillus cereus.The biodegradation performance of benzene by B.cereus was evaluated,and the results showed that benzene could be efficiently biodegraded when the initial benzene concentration was below 150 mg/L.The metabolites of anaerobic nitrate-dependent benzene oxidation by strain B.cereus were identified as phenol and benzoate.The results of substrate interaction between binary combinations for benzene,phenol and benzoate showed that the simultaneous presence of benzene stimulated the degradation of benzoate,whereas the addition of benzene inhibited the degradation of phenol.Benzene degradation by B.cereus was enhanced by the addition of phenol and benzoate,the enhanced effects were more pronounced at higher concentration.To our knowledge,this is the first report that the isolated bacterial culture of B.cereus can efficiently degraded benzene under nitrate reducing conditions.
基金supported by the National Natural Science Foundation of China(32270975,32070907,U24A20371,and T2321005)the National Key R&D Program of China(2023YFA1800200 and 2022YFA1105200)+3 种基金the National Science Fund for Distinguished Young Scholars(32125016)Suzhou Medical College basic frontier innovation cross project(YXY2303027)Suzhou Innovation and Entrepreneurship Leading Talent Program(ZXL2022505)the Priority Acadamic Program Development of Jiangsu Higher Education Institutions(PAPD)。
文摘A recent study by Li et al.[1]was published in Nature and proposed the crucial roles of lactylation in regulating innate immunity.Alanyl-tRNA synthetase 1(AARS1)and AARS2,the intracellular L-lactate sensors,were demonstrated to directly conjugate L-lactate to a lysine residue of substrate proteins.AARS2interacts with cGAS and mediates its lactylation,dampening cGAS-mediated innate antiviral response.
基金the National Natural Science Foundation of China(Nos.21872169,91845109,21688102,and 21825203)the National Key R&D Program of China(No.2016YFA0200200)+2 种基金Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB17020000)China Postdoctoral Science Foundation(No.2019M651997)Natural Science Foundation of Jiangsu Province(No.BK20200257).
文摘The synthesis of high-quality ultrathin overlayers is critically dependent on the surface structure of substrates,especially involving the overlayer–substrate interaction.By using in situ surface measurements,we demonstrate that the overlayer–substrate interaction can be tuned by doping near-surface Ar nanobubbles.The interfacial coupling strength significantly decreases with near-surface Ar nanobubbles,accompanying by an“anisotropic to isotropic”growth transformation.On the substrate containing near-surface Ar,the growth front crosses entire surface atomic steps in both uphill and downhill directions with no difference,and thus,the morphology of the two-dimensional(2D)overlayer exhibits a round-shape.Especially,the round-shaped 2D overlayers coalesce seamlessly with a growth acceleration in the approaching direction,which is barely observed in the synthesis of 2D materials.This can be attributed to the immigration lifetime and diffusion rate of growth species,which depends on the overlayer–substrate interaction and the surface catalysis.Furthermore,the“round to hexagon”morphological transition is achieved by etching-regrowth,revealing the inherent growth kinetics under quasi-freestanding conditions.These findings provide a novel promising way to modulate the growth,coalescence,and etching dynamics of 2D materials on solid surfaces by adjusting the strength of overlayer–substrate interaction,which contributes to optimization of large-scale production of 2D material crystals.
