On February 5, the Dialogue on Building a China-Laos Community with a Shared Future, themed “Focusing on the ‘Action Plan,’ Creating a Better Future Together,” took place in Vientiane, Laos.The opening ceremony fe...On February 5, the Dialogue on Building a China-Laos Community with a Shared Future, themed “Focusing on the ‘Action Plan,’ Creating a Better Future Together,” took place in Vientiane, Laos.The opening ceremony featured speeches by several distinguished vips including Fang Hong, Chinese ambassador to Laos, Daosavanh Kheugmixai, vice president of the Lao National Academy of Politics and Public Administration, Yu Yunquan, vice president of the China International Communications Group (CICG),Sakhon Phommalat, deputy head of the Propaganda and Training Board of the Lao People’s Revolutionary Party (LPRP) Central Committee, Sun Jisheng, vice president of China Foreign Affairs University (CFAU),and Vadthuninyom Duangmala,president of the Diplomatic Academy of Laos.展开更多
On the occasion of the 65th anniversary of the establishment of diplomatic relations between China and Laos,I wish to express,on behalf of the Embassy of the People's Republic of China in the Lao People's Demo...On the occasion of the 65th anniversary of the establishment of diplomatic relations between China and Laos,I wish to express,on behalf of the Embassy of the People's Republic of China in the Lao People's Democratic Republic,our sincere gratitude and highest respect to all friends and personages from various sectors in both countries who have long cared about and supported the development of our bilateral relations.展开更多
Fifty-five-year-old Shi Yizhong never imagined fireflies could become the foundation of a serious business.In 2022,Longshan Village in Huzhou’s Wuxing District collaborated with a young entrepreneurial team to create...Fifty-five-year-old Shi Yizhong never imagined fireflies could become the foundation of a serious business.In 2022,Longshan Village in Huzhou’s Wuxing District collaborated with a young entrepreneurial team to create a firefly campsite-a natural attraction where visitors can observe these glowing insects in a preserved habitat.The site quickly drew waves of tourists,who shared their experience online,recouping its initial investment in just two years.展开更多
The year 2026 marks the 65th anniversary of the establishment of diplomatic relations between China and Laos.The bilateral relations are now at a new starting point where the past has been inherited and a course for t...The year 2026 marks the 65th anniversary of the establishment of diplomatic relations between China and Laos.The bilateral relations are now at a new starting point where the past has been inherited and a course for the future has been set.Looking back,China and Laos have weathered storms together and stood by each other.展开更多
Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar...Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.展开更多
As China and Laos mark the 65th anniversary of their diplomatic relations,the two socialist neighbors stand at a new historical starting point.From revolutionary comrades-in-arms to comprehensive strategic partners,Ch...As China and Laos mark the 65th anniversary of their diplomatic relations,the two socialist neighbors stand at a new historical starting point.From revolutionary comrades-in-arms to comprehensive strategic partners,China and Laos have steadily deepened their bond as"good neighbors,good friends,good comrades,and good partners."展开更多
As a Burundian doctoral student at Nanjing University,my personal journey is closely intertwined with China’s development in the new era and the deepening China-Africa partnership.Recently,my experiences have given m...As a Burundian doctoral student at Nanjing University,my personal journey is closely intertwined with China’s development in the new era and the deepening China-Africa partnership.Recently,my experiences have given me a deeper appreciation of the importance of people-to-people exchanges between China and Africa.展开更多
The year 2026 marks the 65th anniversary of diplomatic ties between China and Laos.During their meeting in Beijing in September 2025,Chinese President Xi Jinping and Lao President Thongloun Sisoulith stressed a need t...The year 2026 marks the 65th anniversary of diplomatic ties between China and Laos.During their meeting in Beijing in September 2025,Chinese President Xi Jinping and Lao President Thongloun Sisoulith stressed a need to advance the construction of the China Laos Economic Corridor and deliver more substantive results across all areas of cooperation.展开更多
Shared energy storage helps lower user investment costs and enhances energy efficiency,which is considered a pivotal driver in accelerating the green transition of energy sectors.In view of the increasing demand for h...Shared energy storage helps lower user investment costs and enhances energy efficiency,which is considered a pivotal driver in accelerating the green transition of energy sectors.In view of the increasing demand for hydrogen,this paper proposes a bi-level optimization of configurations and scheduling for combined cooling,heating,and power(CCHP)microgrid systems considering shared hybrid electric-hydrogen energy storage service.The upper-level model addresses the capacity allocation problem of energy storage stations,while the lower-level model optimizes the operational strategies for the multi-microgrid system(MMS).To resolve the complexity of the coupled bi-level problem,Karush-Kuhn-Tucker(KKT)conditions and the Big-M method are applied to reformulate it into a solvable mixed-integer linear programming(MILP)model,compatible with CPLEX.The economic viability and rationality of the proposed approach are verified through comparisons of three cases.Numerical results show that the proposed approach reduces user annual costs by 20.15%compared to MMS without additional energy storage equipment and achieves 100%renewable absorption.For operators,it yields 5.71 M CNY annual profit with 3.02-year payback.Compared to MMS with electricity sharing,it further cuts user costs by 3.84%,boosts operator profit by 60.71%,and shortens payback by 15.88%.展开更多
The“Forward Together”Dialogue on Building a China-Brunei Community with a Shared Future was held on the morning of February 7 at Universiti Brunei Darussalam(UBD)in Bandar Seri Begawan.Scheduled for the lead-up to t...The“Forward Together”Dialogue on Building a China-Brunei Community with a Shared Future was held on the morning of February 7 at Universiti Brunei Darussalam(UBD)in Bandar Seri Begawan.Scheduled for the lead-up to the 35th anniversary of diplomatic relations between China and Brunei in 2026,the event aimed to deepen strategic mutual trust,build broader consensus on cooperation,and generate both intellectual momentum and practical proposals for advancing a closer China-Brunei community with a shared future.展开更多
Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the mole...Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.展开更多
Neural stem cells(NSCs)and glioblastoma stem cells(GSCs)share a complex regulatory landscape in which cholinergic signaling plays a pivotal role in both neural development and tumor progression.While acetylcholine(ACh...Neural stem cells(NSCs)and glioblastoma stem cells(GSCs)share a complex regulatory landscape in which cholinergic signaling plays a pivotal role in both neural development and tumor progression.While acetylcholine(ACh)regulates NSC quiescence and differentiation within neurogenic niches,glioblastoma cells exploit th ese pathways to enhance their adaptability and invasiveness.The involvement of muscarinic(M3)and nicotinic(α7)receptors in both cell types suggests that glioblastoma retains neural progenitor-like traits,contributing to its plasticity and resilience.This article explores the shared cholinergic mechanisms between NSCs and GSCs,highlighting their role in both neural development and glioblastoma progression.展开更多
On January 15,the list of Top10 News Stories on ChinaASEAN Cooperation 2025 was officially unveiled at a ceremony in Nanning,capital of southwest China’s Guangxi Zhuang Autonomous Region.The event was supervised by C...On January 15,the list of Top10 News Stories on ChinaASEAN Cooperation 2025 was officially unveiled at a ceremony in Nanning,capital of southwest China’s Guangxi Zhuang Autonomous Region.The event was supervised by China International Communications Group(CICG),China Foreign Affairs University(CFAU),and the Publicity Department of the Communist Party of China(CPC)Guangxi Zhuang Autonomous Regional Committee and co-hosted by the CICG Center for AsiaPacific,CFAU Institute of Asian Studies,Guangxi University,and Guangxi International Communication Center.展开更多
Let F be a meromorphic functions family on the unit disc Δ, If for every (the zeros of f is a multiplicity of at least k) and if then and ( ), then F is normal on Δ.
In this article, we deal with the uniqueness problems on meromorphic functions sharing two finite sets in an angular domain instead of the whole plane C. In particular, we investigate the uniqueness for meromorphic fu...In this article, we deal with the uniqueness problems on meromorphic functions sharing two finite sets in an angular domain instead of the whole plane C. In particular, we investigate the uniqueness for meromorphic functions of infinite order in an angular domain and obtain some results. Moreover, examples show that the conditions in theorems are necessary.展开更多
We studied the normality criterion for families of meromorphic functions related to shared sets. Let F be a family of meromorphic functions on the unit disc △, a and b be distinct non-zero values, S={a,b}, and k be a...We studied the normality criterion for families of meromorphic functions related to shared sets. Let F be a family of meromorphic functions on the unit disc △, a and b be distinct non-zero values, S={a,b}, and k be a positive integer. If for every f∈ F, i） the zeros of f（z） have a multiplicity of at least k＋ 1, and ii） E^-f（k）（S） lohtain in E^-f（S）, then F is normal on .4. At the same time, the corresponding results of normal function are also proved.展开更多
In this paper,we study the normality criterion for families of meromorphic functions concerning shared set depending on f∈F.Let F be a family of meromorphic functions in the unit disc A.For each f∈F,all zeros of f h...In this paper,we study the normality criterion for families of meromorphic functions concerning shared set depending on f∈F.Let F be a family of meromorphic functions in the unit disc A.For each f∈F,all zeros of f have multiplicity at least 2 and there exist nonzero complex numbers b_f,c_f satisfying(i) b_f/c_f is a constant;(ii) min{σ(0,b_f),σ(0,c_f),σ(b_f,c_f)} ≥m for some m > 0;(iii) E_f'(S_f)■ E_f(S_f),where S_f = {b_f,c_f}.Then F is normal in A.At the same time,the corresponding results are also proved.The results in this paper improve and generalize the related results展开更多
文摘On February 5, the Dialogue on Building a China-Laos Community with a Shared Future, themed “Focusing on the ‘Action Plan,’ Creating a Better Future Together,” took place in Vientiane, Laos.The opening ceremony featured speeches by several distinguished vips including Fang Hong, Chinese ambassador to Laos, Daosavanh Kheugmixai, vice president of the Lao National Academy of Politics and Public Administration, Yu Yunquan, vice president of the China International Communications Group (CICG),Sakhon Phommalat, deputy head of the Propaganda and Training Board of the Lao People’s Revolutionary Party (LPRP) Central Committee, Sun Jisheng, vice president of China Foreign Affairs University (CFAU),and Vadthuninyom Duangmala,president of the Diplomatic Academy of Laos.
文摘On the occasion of the 65th anniversary of the establishment of diplomatic relations between China and Laos,I wish to express,on behalf of the Embassy of the People's Republic of China in the Lao People's Democratic Republic,our sincere gratitude and highest respect to all friends and personages from various sectors in both countries who have long cared about and supported the development of our bilateral relations.
文摘Fifty-five-year-old Shi Yizhong never imagined fireflies could become the foundation of a serious business.In 2022,Longshan Village in Huzhou’s Wuxing District collaborated with a young entrepreneurial team to create a firefly campsite-a natural attraction where visitors can observe these glowing insects in a preserved habitat.The site quickly drew waves of tourists,who shared their experience online,recouping its initial investment in just two years.
文摘The year 2026 marks the 65th anniversary of the establishment of diplomatic relations between China and Laos.The bilateral relations are now at a new starting point where the past has been inherited and a course for the future has been set.Looking back,China and Laos have weathered storms together and stood by each other.
文摘Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.
文摘As China and Laos mark the 65th anniversary of their diplomatic relations,the two socialist neighbors stand at a new historical starting point.From revolutionary comrades-in-arms to comprehensive strategic partners,China and Laos have steadily deepened their bond as"good neighbors,good friends,good comrades,and good partners."
文摘As a Burundian doctoral student at Nanjing University,my personal journey is closely intertwined with China’s development in the new era and the deepening China-Africa partnership.Recently,my experiences have given me a deeper appreciation of the importance of people-to-people exchanges between China and Africa.
文摘The year 2026 marks the 65th anniversary of diplomatic ties between China and Laos.During their meeting in Beijing in September 2025,Chinese President Xi Jinping and Lao President Thongloun Sisoulith stressed a need to advance the construction of the China Laos Economic Corridor and deliver more substantive results across all areas of cooperation.
文摘Shared energy storage helps lower user investment costs and enhances energy efficiency,which is considered a pivotal driver in accelerating the green transition of energy sectors.In view of the increasing demand for hydrogen,this paper proposes a bi-level optimization of configurations and scheduling for combined cooling,heating,and power(CCHP)microgrid systems considering shared hybrid electric-hydrogen energy storage service.The upper-level model addresses the capacity allocation problem of energy storage stations,while the lower-level model optimizes the operational strategies for the multi-microgrid system(MMS).To resolve the complexity of the coupled bi-level problem,Karush-Kuhn-Tucker(KKT)conditions and the Big-M method are applied to reformulate it into a solvable mixed-integer linear programming(MILP)model,compatible with CPLEX.The economic viability and rationality of the proposed approach are verified through comparisons of three cases.Numerical results show that the proposed approach reduces user annual costs by 20.15%compared to MMS without additional energy storage equipment and achieves 100%renewable absorption.For operators,it yields 5.71 M CNY annual profit with 3.02-year payback.Compared to MMS with electricity sharing,it further cuts user costs by 3.84%,boosts operator profit by 60.71%,and shortens payback by 15.88%.
文摘The“Forward Together”Dialogue on Building a China-Brunei Community with a Shared Future was held on the morning of February 7 at Universiti Brunei Darussalam(UBD)in Bandar Seri Begawan.Scheduled for the lead-up to the 35th anniversary of diplomatic relations between China and Brunei in 2026,the event aimed to deepen strategic mutual trust,build broader consensus on cooperation,and generate both intellectual momentum and practical proposals for advancing a closer China-Brunei community with a shared future.
基金supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(RS-2023-00248378 and NRF-2020R1A6A1A03043708).
文摘Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.
文摘Neural stem cells(NSCs)and glioblastoma stem cells(GSCs)share a complex regulatory landscape in which cholinergic signaling plays a pivotal role in both neural development and tumor progression.While acetylcholine(ACh)regulates NSC quiescence and differentiation within neurogenic niches,glioblastoma cells exploit th ese pathways to enhance their adaptability and invasiveness.The involvement of muscarinic(M3)and nicotinic(α7)receptors in both cell types suggests that glioblastoma retains neural progenitor-like traits,contributing to its plasticity and resilience.This article explores the shared cholinergic mechanisms between NSCs and GSCs,highlighting their role in both neural development and glioblastoma progression.
文摘On January 15,the list of Top10 News Stories on ChinaASEAN Cooperation 2025 was officially unveiled at a ceremony in Nanning,capital of southwest China’s Guangxi Zhuang Autonomous Region.The event was supervised by China International Communications Group(CICG),China Foreign Affairs University(CFAU),and the Publicity Department of the Communist Party of China(CPC)Guangxi Zhuang Autonomous Regional Committee and co-hosted by the CICG Center for AsiaPacific,CFAU Institute of Asian Studies,Guangxi University,and Guangxi International Communication Center.
文摘Let F be a meromorphic functions family on the unit disc Δ, If for every (the zeros of f is a multiplicity of at least k) and if then and ( ), then F is normal on Δ.
基金Supported by the NNSFC (10671109)the NSFFC(2008J0190)+1 种基金the Research Fund for Talent Introduction of Ningde Teachers College (2009Y019)the Scitific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
文摘In this article, we deal with the uniqueness problems on meromorphic functions sharing two finite sets in an angular domain instead of the whole plane C. In particular, we investigate the uniqueness for meromorphic functions of infinite order in an angular domain and obtain some results. Moreover, examples show that the conditions in theorems are necessary.
文摘We studied the normality criterion for families of meromorphic functions related to shared sets. Let F be a family of meromorphic functions on the unit disc △, a and b be distinct non-zero values, S={a,b}, and k be a positive integer. If for every f∈ F, i） the zeros of f（z） have a multiplicity of at least k＋ 1, and ii） E^-f（k）（S） lohtain in E^-f（S）, then F is normal on .4. At the same time, the corresponding results of normal function are also proved.
基金Supported by the National Natural Science Foundation of China（l1461070, 11271090） Supported by the Natural Science Foundation of Guangdong Province（S2012010010121）
文摘In this paper,we study the normality criterion for families of meromorphic functions concerning shared set depending on f∈F.Let F be a family of meromorphic functions in the unit disc A.For each f∈F,all zeros of f have multiplicity at least 2 and there exist nonzero complex numbers b_f,c_f satisfying(i) b_f/c_f is a constant;(ii) min{σ(0,b_f),σ(0,c_f),σ(b_f,c_f)} ≥m for some m > 0;(iii) E_f'(S_f)■ E_f(S_f),where S_f = {b_f,c_f}.Then F is normal in A.At the same time,the corresponding results are also proved.The results in this paper improve and generalize the related results
