Liver transplantation,as an effective therapy for patients with liver cancer,plays an important role in improving the quality of life of patients.However,the com-plexity and trauma of liver transplantation can easily ...Liver transplantation,as an effective therapy for patients with liver cancer,plays an important role in improving the quality of life of patients.However,the com-plexity and trauma of liver transplantation can easily lead to the occurrence of malnutrition in patients,and then increase the risk of postoperative complica-tions,which has aroused widespread clinical attention.Reasonable nutritional support can not only maintain the stability of the body’s internal environment,reduce the occurrence of complications,but also promote the recovery of liver and other organ functions.In recent years,with the in-depth understanding of nut-ritional metabolism after liver transplantation,the application of enteral nutrition and parenteral nutrition in nutritional support after liver transplantation has been increasingly extensive and achieved remarkable results.This paper discusses the effect of early postoperative nutritional intervention on patients with liver cancer and liver transplantation,and combined with its mechanism of action,can better understand the effectiveness of intervention,and provide reference for the deve-lopment of scientific and reasonable nutritional support programs in clinical pra-ctice.展开更多
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research fun...Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.展开更多
With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical syst...With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical system.The clinical practice ability of nursing staff is directly related to the safety of patient diagnosis and treatment and the rehabilitation process.However,the current clinical nursing talent training model is facing bottlenecks such as limited practical scenarios and fragmented case cognition.This study focuses on the teaching application of augmented reality(AR)technology in hospital Settings and systematically reviews the research progress on the improvement of clinical practice ability of trainee nurses based on the AR immersive teaching model.By constructing a clinical teaching scenario that integrates virtual and real,AR technology can dynamically simulate complex case handling processes and enhance nursing students’three-dimensional cognition of condition assessment,operation norms,and emergency plans.Hospitals,as the core base for practical teaching,can effectively shorten the connection cycle between theoretical teaching and clinical practice by integrating AR technology,improve the clinical practice level of trainee nurses,and provide an innovative model for optimizing the path of clinical nursing talent cultivation.展开更多
Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,pro...Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,professional adaptation,and quality of communication with patients.The causes of emotional expression difficulties include individual personality,emotional intelligence,educational background,and socio-cultural pressures.To address this issue,it is recommended to enhance nursing students emotional expression and regulation capabilities through psychological interventions,emotional intelligence training,and optimization of educational systems,thereby improving their mental health and career development,ultimately enhancing nursing service quality and doctor-patient relationships.展开更多
Atherosclerosis(AS)is the core pathological basis of Cardiovascular Disease(CVD)worldwide.Its occurrence and development involve endothelial dysfunction,lipid deposition,chronic inflammation and abnormal proliferation...Atherosclerosis(AS)is the core pathological basis of Cardiovascular Disease(CVD)worldwide.Its occurrence and development involve endothelial dysfunction,lipid deposition,chronic inflammation and abnormal proliferation of smooth muscle cells.Berberine(BBR),also known as berberine,is an isoquinoline alkaloid extracted from traditional Chinese medicine such as Coptis coptidis and Phelloberia angustifolia.It has traditionally been used for antibacterial and anti-inflammatory treatment.In recent years,it has been found that it has multi-target metabolic regulation and anti-inflammatory properties,showing significant potential in the prevention and treatment of AS.This article systematically reviews the research progress of berberine in the treatment of AS by improving endothelial function,regulating lipid metabolism,inhibiting inflammatory response,regulating smooth muscle cell phenotypic transformation,and anti-oxidative stress,and discusses the current status and challenges of its clinical application.展开更多
Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psych...Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psychomotor agitation,and restlessness.Postoperative delirium(POD),a common complication particularly in elderly patients,significantly impacts recovery by prolonging mechanical ventilation,neurosurgical intensive care unit stays,and overall hospitalization durations,while severely diminishing patients’quality of life after discharge.Despite its prevalence,POD remains underrecognized in clinical practice,with significant gaps in its diagnosis and management.This review explores the definition,diagnostic criteria,underlying pathogenesis,and associated risk factors of POD in neurosurgical patients,aiming to offer valuable insights for improving clinical diagnosis and therapeutic strategies.展开更多
Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has...Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has become a key problem restricting its development.Cyclodextrins and their derivatives,with their unique cyclic structures,can form inclusion complexes with TMP to improve its properties.This article reviews the pharmacological characteristics of TMP,the types and properties of common cyclodextrins,focusing on introducing various preparation methods of trimethoprim cyclodextrin inclusion complexes and multiple characterization methods for identifying the inclusion complexes,aiming to provide a reference for further research and development of trimethoprim cyclodextrin inclusion complexes.展开更多
Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is l...Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is limited by adverse effects and significant inter-individual variability.Non-pharmacological therapies from traditional medicine have emerged as promising adjuncts owing to their favorable safety profiles,minimal side effects,and high patient compliance.These therapies,including acupoint stimulation,meditation,and yoga,produce antidepressant effects by reducing neuroinflammation,modulating neurotransmitter release,enhancing neuroplasticity,and regulating the gut-brain axis.This review summarizes clinical applications and mechanistic insights of traditional medicine’s non-pharmacological therapies for depression,providing a scientific rationale for their integration into comprehensive management.展开更多
This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,includi...This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,including deepening of theoretical research,innovation of practice mode,optimization of policy support and cultural adaptation research.展开更多
Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy re...Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy refers to an individual’s ability to recognize,manage,and prevent suicide-related problems.This article offers a comprehensive review of the concepts,assessment tools,factors,and interventions of suicide literacy,with the goal of helping individuals to better understand suicidal behaviors and providing a scientific basis for developing effective suicide prevention strategies and measures to advance the progress of suicide prevention.展开更多
Laminated metal composites(LMCs)have widespread application prospects and are set to become indispensable in addressing modern engineering challenges owing to their capability of leveraging the synergy between differe...Laminated metal composites(LMCs)have widespread application prospects and are set to become indispensable in addressing modern engineering challenges owing to their capability of leveraging the synergy between different metals and tailoring performance by flexibly regulating the layered configuration.The plastic forming process,as a promising advanced manufacturing technology,has been increasingly adopted for the fabrication of LMC components due to its advantages of high material utilization rate,high production efficiency,and excellent mechanical properties of the product.This review delved into the research progress on the plastic-forming process of LMCs,including rolling,extrusion,spinning,etc.It outlined the forming principles,unique characteristics,bonding mechanisms,and the influence of key process parameters on deformation,microstructure,and property.This review focused on the heterogeneous deformation and interfacial regulation of LMCs,providing insights into the mechanisms of heterogeneous deformation,damage and fracture,and formation mechanisms of intermetallic compounds.It also delineated the experimental characterization and numerical modeling methods to elucidate the heterogeneous deformation behavior,as well as the approaches to evaluating and enhancing the performance of LMCs.Finally,the challenges and prospects of manufacturing high-performance LMCs by plastic forming process are orchestrated.展开更多
In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life...In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life of patients.The conventional treatment methods include weight loss and regulating the body’s metabolism.Semaglutide,as a glucagon-like peptide-1 receptor agonist(GLP-1RA),mainly reduces patients’appetite,decreases their craving for high-fat and high-sugar foods,regulates hypothalamic feeding behavior,inhibits gastric emptying and gastrointestinal motility,and ultimately leads to weight loss.Metformin mainly acts on extra-islet tissues,increasing glucose utilization,reducing glucose production,and ultimately lowering blood glucose levels.Based on this,this article reviews relevant literature on authoritative websites such as CNKI and Wanfang,organizes the data,and analyzes the research progress of semaglutide combined with metformin in the treatment of obese T2DM.The aim is to bring more treatment options for obese T2DM and promote better prognosis for patients.展开更多
TWith the global acceleration of population aging,the number of patients with Parkinson’s disease(PD)continues to rise,and falls have become one of the main issues affecting their health and quality of life.The risk ...TWith the global acceleration of population aging,the number of patients with Parkinson’s disease(PD)continues to rise,and falls have become one of the main issues affecting their health and quality of life.The risk of falls is significantly increased in PD patients due to multiple factors,including motor symptoms,non-motor symptoms,medication side effects,unsafe environments,and psychological or behavioral factors.Falls can cause severe physical injuries,reduce independence,and trigger psychological problems such as depression and anxiety.In recent years,both domestic and international studies have made progress in identifying fall risk factors,developing risk assessment tools,and implementing multidimensional prevention strategies.Effective preventive measures include high-risk population screening,disease progression monitoring,exercise rehabilitation training,management of non-motor symptoms,medication optimization,environmental safety modifications,and psychological-behavioral interventions.Scientific and systematic comprehensive management can help reduce the incidence of falls among PD patients and improve their quality of life.This review summarizes the latest research advances on the main risk factors and preventive strategies for falls in patients with Parkinson’s disease,providing a theoretical basis and practical guidance for clinical nursing and rehabilitation interventions.展开更多
Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchym...Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchymal stem cells(hUC-MSCs)have emerged as a research hotspot due to their unique differentiation potential,remarkable regenerative capacity,and significant immune regulatory properties.Studies demonstrate that it can improve liver function through multiple mechanisms,promote hepatocyte regeneration,and reduce hepatic injury.Additionally,their role in regulating inflammatory responses provides new therapeutic approaches for ALF.This review systematically examines the latest research progress on hUC-MSCs in ALF treatment,focusing on their mechanisms of action,therapeutic efficacy,and clinical application prospects,aiming to provide valuable references for future research and clinical practice.展开更多
Aim:To review the selection of treatment methods for symptomatic intracranial atherosclerotic stenosis(sICAS)in the acute phase and the progress of research on sICAS interventional therapy based on the latest research...Aim:To review the selection of treatment methods for symptomatic intracranial atherosclerotic stenosis(sICAS)in the acute phase and the progress of research on sICAS interventional therapy based on the latest research technology development.Intracranial atherosclerotic stenosis(ICAS)is the most common cause of ischemic stroke in our country.Currently,treatment is primarily based on pharmacotherapy.In recent years,with the changes and development of endovascular treatment techniques,materials,and treatment concepts,many new research findings have emerged.This article will review the selection of treatment methods for symptomatic intracranial atherosclerotic stenosis(sICAS)in the acute phase and the progress of research on sICAS interventional therapy based on the latest research technology development.展开更多
Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the periop...Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the perioperative period,including preoperative risk assessment and airway management,intraoperative neuromonitoring nursing coordination,postoperative drainage,and incision management.However,single Western medicine nursing often cannot fully meet the multifaceted needs of patients,especially in emotional nursing and the management of postoperative adverse reactions.The involvement of traditional Chinese medicine nursing techniques provides an effective complement to nursing work.Through integrated Chinese and Western medicine nursing,it is possible not only to improve patients’preoperative anxiety and postoperative nausea and vomiting but also to effectively manage postoperative pain,enhancing the overall comfort and recovery speed of patients.展开更多
This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristi...This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristics,mechanisms of its impact on clinical outcomes and quality of life,as well as targeted intervention strategies.Research indicates that health literacy significantly improves patient prognosis through pathways such as enhancing treatment adherence,optimizing doctor-patient communication,and strengthening self-management capabilities.This review also points out that future research needs to focus on developing cross-cultural assessment tools,exploring neurocognitive mechanisms,integrating digital technologies,and promoting policy translation to address the new challenges in the era of chronic disease management for lung cancer.展开更多
This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for de...This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for developing effective treatment strategies and improving patients’ quality of life. It also points out the challenges of current treatment, such as patient compliance and limitations of treatment methods, and looks at future treatment directions.展开更多
In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This pap...In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This paper summarizes the research results on common traditional Chinese medicines for lowering blood sugar in recent years.These results lay a theoretical foundation for the future clinical development and use of hypoglycemic Chinese medicine,the improvement of the quality standards of hypoglycemic Chinese medicine,and the in-depth research on the mechanisms.展开更多
Grain character is an important factor in yield components of rice. Progress of genetic research on grain length, grain width, lengthwidth ratio, grain thickness and grain weight were reviewed. It＇s considered that t...Grain character is an important factor in yield components of rice. Progress of genetic research on grain length, grain width, lengthwidth ratio, grain thickness and grain weight were reviewed. It＇s considered that the genetic research on grain shape in rice has achieved considerable progress by exploration on genetic research for many years, but there are still some aspects waiting to be strengthened such as the grain shape, the genetic mechanism of grain shape and the genetic and potential value of grain shape in characteristic germplasm resources, etc.展开更多
文摘Liver transplantation,as an effective therapy for patients with liver cancer,plays an important role in improving the quality of life of patients.However,the com-plexity and trauma of liver transplantation can easily lead to the occurrence of malnutrition in patients,and then increase the risk of postoperative complica-tions,which has aroused widespread clinical attention.Reasonable nutritional support can not only maintain the stability of the body’s internal environment,reduce the occurrence of complications,but also promote the recovery of liver and other organ functions.In recent years,with the in-depth understanding of nut-ritional metabolism after liver transplantation,the application of enteral nutrition and parenteral nutrition in nutritional support after liver transplantation has been increasingly extensive and achieved remarkable results.This paper discusses the effect of early postoperative nutritional intervention on patients with liver cancer and liver transplantation,and combined with its mechanism of action,can better understand the effectiveness of intervention,and provide reference for the deve-lopment of scientific and reasonable nutritional support programs in clinical pra-ctice.
文摘Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.
文摘With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical system.The clinical practice ability of nursing staff is directly related to the safety of patient diagnosis and treatment and the rehabilitation process.However,the current clinical nursing talent training model is facing bottlenecks such as limited practical scenarios and fragmented case cognition.This study focuses on the teaching application of augmented reality(AR)technology in hospital Settings and systematically reviews the research progress on the improvement of clinical practice ability of trainee nurses based on the AR immersive teaching model.By constructing a clinical teaching scenario that integrates virtual and real,AR technology can dynamically simulate complex case handling processes and enhance nursing students’three-dimensional cognition of condition assessment,operation norms,and emergency plans.Hospitals,as the core base for practical teaching,can effectively shorten the connection cycle between theoretical teaching and clinical practice by integrating AR technology,improve the clinical practice level of trainee nurses,and provide an innovative model for optimizing the path of clinical nursing talent cultivation.
基金Supported by National Natural Science Foundation of China(71774049).
文摘Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,professional adaptation,and quality of communication with patients.The causes of emotional expression difficulties include individual personality,emotional intelligence,educational background,and socio-cultural pressures.To address this issue,it is recommended to enhance nursing students emotional expression and regulation capabilities through psychological interventions,emotional intelligence training,and optimization of educational systems,thereby improving their mental health and career development,ultimately enhancing nursing service quality and doctor-patient relationships.
文摘Atherosclerosis(AS)is the core pathological basis of Cardiovascular Disease(CVD)worldwide.Its occurrence and development involve endothelial dysfunction,lipid deposition,chronic inflammation and abnormal proliferation of smooth muscle cells.Berberine(BBR),also known as berberine,is an isoquinoline alkaloid extracted from traditional Chinese medicine such as Coptis coptidis and Phelloberia angustifolia.It has traditionally been used for antibacterial and anti-inflammatory treatment.In recent years,it has been found that it has multi-target metabolic regulation and anti-inflammatory properties,showing significant potential in the prevention and treatment of AS.This article systematically reviews the research progress of berberine in the treatment of AS by improving endothelial function,regulating lipid metabolism,inhibiting inflammatory response,regulating smooth muscle cell phenotypic transformation,and anti-oxidative stress,and discusses the current status and challenges of its clinical application.
基金Supported by Science and Technology Program of Nantong City,No.Key003Nantong Young Medical Expert,No.46+2 种基金the Science and Technology Program of Nantong Health Committee,No.MA2019003,No.MA2021017,and No.MSZ2024038Science and Technology Program of Nantong City,No.JCZ2022040Kangda College of Nanjing Medical University,No.KD2021JYYJYB025,No.KD2022KYJJZD022,and No.KD2024KYJJ289.
文摘Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psychomotor agitation,and restlessness.Postoperative delirium(POD),a common complication particularly in elderly patients,significantly impacts recovery by prolonging mechanical ventilation,neurosurgical intensive care unit stays,and overall hospitalization durations,while severely diminishing patients’quality of life after discharge.Despite its prevalence,POD remains underrecognized in clinical practice,with significant gaps in its diagnosis and management.This review explores the definition,diagnostic criteria,underlying pathogenesis,and associated risk factors of POD in neurosurgical patients,aiming to offer valuable insights for improving clinical diagnosis and therapeutic strategies.
基金Academic Fund for Students of Foshan University in 2024(Project No.:xsjj202409zrb11)。
文摘Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has become a key problem restricting its development.Cyclodextrins and their derivatives,with their unique cyclic structures,can form inclusion complexes with TMP to improve its properties.This article reviews the pharmacological characteristics of TMP,the types and properties of common cyclodextrins,focusing on introducing various preparation methods of trimethoprim cyclodextrin inclusion complexes and multiple characterization methods for identifying the inclusion complexes,aiming to provide a reference for further research and development of trimethoprim cyclodextrin inclusion complexes.
基金supported by the Beijing Natural Science Foundation(7244491)Beijing TCM Science and Technology Development Fund Project(BJZYON-2023-05)+2 种基金Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ15-YQ-048,ZZ-YQ2023006)Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202409)Science and Technology Innovation Project of the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences(CIZJS2025023).
文摘Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is limited by adverse effects and significant inter-individual variability.Non-pharmacological therapies from traditional medicine have emerged as promising adjuncts owing to their favorable safety profiles,minimal side effects,and high patient compliance.These therapies,including acupoint stimulation,meditation,and yoga,produce antidepressant effects by reducing neuroinflammation,modulating neurotransmitter release,enhancing neuroplasticity,and regulating the gut-brain axis.This review summarizes clinical applications and mechanistic insights of traditional medicine’s non-pharmacological therapies for depression,providing a scientific rationale for their integration into comprehensive management.
基金Supported by National Natural Science Foundation of China(71774049).
文摘This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,including deepening of theoretical research,innovation of practice mode,optimization of policy support and cultural adaptation research.
文摘Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy refers to an individual’s ability to recognize,manage,and prevent suicide-related problems.This article offers a comprehensive review of the concepts,assessment tools,factors,and interventions of suicide literacy,with the goal of helping individuals to better understand suicidal behaviors and providing a scientific basis for developing effective suicide prevention strategies and measures to advance the progress of suicide prevention.
基金supported by the National Natural Science Foundation of China(Grant Nos.52305361,52105337,52475354,and 52090043)the BK21 Four program(SNU Materials Education/Research Division for Creative Global Leaders)+1 种基金the China Postdoctoral Science Foundation(Grant No.2023M741245),and the National Key Research and Development Program of China(Grant No.2022YFB3706903)support from the Ko-rean Ministry of Trade,Industry and Energy(MOTIE,Korea)(Grant No.20022438).
文摘Laminated metal composites(LMCs)have widespread application prospects and are set to become indispensable in addressing modern engineering challenges owing to their capability of leveraging the synergy between different metals and tailoring performance by flexibly regulating the layered configuration.The plastic forming process,as a promising advanced manufacturing technology,has been increasingly adopted for the fabrication of LMC components due to its advantages of high material utilization rate,high production efficiency,and excellent mechanical properties of the product.This review delved into the research progress on the plastic-forming process of LMCs,including rolling,extrusion,spinning,etc.It outlined the forming principles,unique characteristics,bonding mechanisms,and the influence of key process parameters on deformation,microstructure,and property.This review focused on the heterogeneous deformation and interfacial regulation of LMCs,providing insights into the mechanisms of heterogeneous deformation,damage and fracture,and formation mechanisms of intermetallic compounds.It also delineated the experimental characterization and numerical modeling methods to elucidate the heterogeneous deformation behavior,as well as the approaches to evaluating and enhancing the performance of LMCs.Finally,the challenges and prospects of manufacturing high-performance LMCs by plastic forming process are orchestrated.
文摘In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life of patients.The conventional treatment methods include weight loss and regulating the body’s metabolism.Semaglutide,as a glucagon-like peptide-1 receptor agonist(GLP-1RA),mainly reduces patients’appetite,decreases their craving for high-fat and high-sugar foods,regulates hypothalamic feeding behavior,inhibits gastric emptying and gastrointestinal motility,and ultimately leads to weight loss.Metformin mainly acts on extra-islet tissues,increasing glucose utilization,reducing glucose production,and ultimately lowering blood glucose levels.Based on this,this article reviews relevant literature on authoritative websites such as CNKI and Wanfang,organizes the data,and analyzes the research progress of semaglutide combined with metformin in the treatment of obese T2DM.The aim is to bring more treatment options for obese T2DM and promote better prognosis for patients.
文摘TWith the global acceleration of population aging,the number of patients with Parkinson’s disease(PD)continues to rise,and falls have become one of the main issues affecting their health and quality of life.The risk of falls is significantly increased in PD patients due to multiple factors,including motor symptoms,non-motor symptoms,medication side effects,unsafe environments,and psychological or behavioral factors.Falls can cause severe physical injuries,reduce independence,and trigger psychological problems such as depression and anxiety.In recent years,both domestic and international studies have made progress in identifying fall risk factors,developing risk assessment tools,and implementing multidimensional prevention strategies.Effective preventive measures include high-risk population screening,disease progression monitoring,exercise rehabilitation training,management of non-motor symptoms,medication optimization,environmental safety modifications,and psychological-behavioral interventions.Scientific and systematic comprehensive management can help reduce the incidence of falls among PD patients and improve their quality of life.This review summarizes the latest research advances on the main risk factors and preventive strategies for falls in patients with Parkinson’s disease,providing a theoretical basis and practical guidance for clinical nursing and rehabilitation interventions.
基金Key Project of the Hunan Provincial Department of Education(Project No.:21A0024):Effect of Exosomes Derived from Umbilical Cord Blood MSCs Transfected with VEGF165 Gene on Inflammatory Apoptosis of Hepatocytes in Rats with Acute Liver Failure.
文摘Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchymal stem cells(hUC-MSCs)have emerged as a research hotspot due to their unique differentiation potential,remarkable regenerative capacity,and significant immune regulatory properties.Studies demonstrate that it can improve liver function through multiple mechanisms,promote hepatocyte regeneration,and reduce hepatic injury.Additionally,their role in regulating inflammatory responses provides new therapeutic approaches for ALF.This review systematically examines the latest research progress on hUC-MSCs in ALF treatment,focusing on their mechanisms of action,therapeutic efficacy,and clinical application prospects,aiming to provide valuable references for future research and clinical practice.
文摘Aim:To review the selection of treatment methods for symptomatic intracranial atherosclerotic stenosis(sICAS)in the acute phase and the progress of research on sICAS interventional therapy based on the latest research technology development.Intracranial atherosclerotic stenosis(ICAS)is the most common cause of ischemic stroke in our country.Currently,treatment is primarily based on pharmacotherapy.In recent years,with the changes and development of endovascular treatment techniques,materials,and treatment concepts,many new research findings have emerged.This article will review the selection of treatment methods for symptomatic intracranial atherosclerotic stenosis(sICAS)in the acute phase and the progress of research on sICAS interventional therapy based on the latest research technology development.
文摘Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the perioperative period,including preoperative risk assessment and airway management,intraoperative neuromonitoring nursing coordination,postoperative drainage,and incision management.However,single Western medicine nursing often cannot fully meet the multifaceted needs of patients,especially in emotional nursing and the management of postoperative adverse reactions.The involvement of traditional Chinese medicine nursing techniques provides an effective complement to nursing work.Through integrated Chinese and Western medicine nursing,it is possible not only to improve patients’preoperative anxiety and postoperative nausea and vomiting but also to effectively manage postoperative pain,enhancing the overall comfort and recovery speed of patients.
基金Supported by National Natural Science Foundation of China(71774049).
文摘This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristics,mechanisms of its impact on clinical outcomes and quality of life,as well as targeted intervention strategies.Research indicates that health literacy significantly improves patient prognosis through pathways such as enhancing treatment adherence,optimizing doctor-patient communication,and strengthening self-management capabilities.This review also points out that future research needs to focus on developing cross-cultural assessment tools,exploring neurocognitive mechanisms,integrating digital technologies,and promoting policy translation to address the new challenges in the era of chronic disease management for lung cancer.
文摘This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for developing effective treatment strategies and improving patients’ quality of life. It also points out the challenges of current treatment, such as patient compliance and limitations of treatment methods, and looks at future treatment directions.
文摘In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This paper summarizes the research results on common traditional Chinese medicines for lowering blood sugar in recent years.These results lay a theoretical foundation for the future clinical development and use of hypoglycemic Chinese medicine,the improvement of the quality standards of hypoglycemic Chinese medicine,and the in-depth research on the mechanisms.
基金Supported by the Key Project of Science and Technology Support Plan of Hunan Province(2008NK2003)~~
文摘Grain character is an important factor in yield components of rice. Progress of genetic research on grain length, grain width, lengthwidth ratio, grain thickness and grain weight were reviewed. It＇s considered that the genetic research on grain shape in rice has achieved considerable progress by exploration on genetic research for many years, but there are still some aspects waiting to be strengthened such as the grain shape, the genetic mechanism of grain shape and the genetic and potential value of grain shape in characteristic germplasm resources, etc.
