Reservoir-induced landslides in China's Three Gorges Reservoir area are prone to tensile cracks due to the influenceof their own weight and fluctuationsin water levels.The presence of cracks indicates that the ten...Reservoir-induced landslides in China's Three Gorges Reservoir area are prone to tensile cracks due to the influenceof their own weight and fluctuationsin water levels.The presence of cracks indicates that the tensile stress in the area has exceeded the tensile strength of the soil,leading to local instability.To explore the impact of tensile failure behavior on the stability and failure modes of reservoir landslides,the Huangtupo Riverside Slump#1 is taken as a case study.By considering local tensile failure,potential tensile cracks are incorporated into the analysis via the limit equilibrium method and reliability theory.The reliability of landslides under different tensile failure scenarios is quantified.Strain-softening characteristics of the soil are combined to further analyze the failure transmission path of the landslide.Finally,these potential failure modes were validated through physical model tests.The results show that cracks developing at rear positions reduce the stability of the slope and increase the probability of instability.During the destruction process,retrogressive failures with multiple sliding surfaces are likely to occur.However,tensile failure at the forefront reduces the likelihood of an individual slide mass descending.Progressive failure results in both regular and skip transmission patterns.Additionally,cracks and water level changes can also lead to shifts in the positions of the most dangerous blocks.Therefore,in practical landslide analysis and prevention,it is necessary to consider local tensile damage and identify potential tensile crack locations in advance to optimize prevention measures and accurately evaluate landslide risk.展开更多
In reliability analyses,the absence of a priori information on the most probable point of failure(MPP)may result in overlooking critical points,thereby leading to biased assessment outcomes.Moreover,second-order relia...In reliability analyses,the absence of a priori information on the most probable point of failure(MPP)may result in overlooking critical points,thereby leading to biased assessment outcomes.Moreover,second-order reliability methods exhibit limited accuracy in highly nonlinear scenarios.To overcome these challenges,a novel reliability analysis strategy based on a multimodal differential evolution algorithm and a hypersphere integration method is proposed.Initially,the penalty function method is employed to reformulate the MPP search problem as a conditionally constrained optimization task.Subsequently,a differential evolution algorithm incorporating a population delineation strategy is utilized to identify all MPPs.Finally,a paraboloid equation is constructed based on the curvature of the limit-state function at the MPPs,and the failure probability of the structure is calculated by using the hypersphere integration method.The localization effectiveness of the MPPs is compared through multiple numerical cases and two engineering examples,with accuracy comparisons of failure probabilities against the first-order reliability method(FORM)and the secondorder reliability method(SORM).The results indicate that the method effectively identifies existing MPPs and achieves higher solution precision.展开更多
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ...This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.展开更多
Autonomous Underwater Vehicles(AUVs)are pivotal for deep-sea exploration and resource exploitation,yet their reliability in extreme underwater environments remains a critical barrier to widespread deployment.Through s...Autonomous Underwater Vehicles(AUVs)are pivotal for deep-sea exploration and resource exploitation,yet their reliability in extreme underwater environments remains a critical barrier to widespread deployment.Through systematic analysis of 150 peer-reviewed studies employing mixed-methods research,this review yields three principal advancements to the reliability analysis of AUVs.First,based on the hierarchical functional division of AUVs into six subsystems(propulsion system,navigation system,communication system,power system,environmental detection system,and emergency system),this study systematically identifies the primary failure modes and potential failure causes of each subsystem,providing theoretical support for fault diagnosis and reliability optimization.Subsequently,a comprehensive review of AUV reliability analysis methods is conducted from three perspectives:analytical methods,simulated methods,and surrogate model methods.The applicability and limitations of each method are critically analyzed to offer insights into their suitability for engineering applications.Finally,the study highlights key challenges and research hotpots in AUV reliability analysis,including reliability analysis under limited data,AI-driven reliability analysis,and human reliability analysis.Furthermore,the potential of multi-sensor data fusion,edge computing,and advanced materials in enhancing AUV environmental adaptability and reliability is explored.展开更多
Reliability analysis of soil slopes under rainfall is an important task for landslide risk assessment.Previous studies rarely contribute to the probabilistic analysis of slope stability under rainfall with reinforceme...Reliability analysis of soil slopes under rainfall is an important task for landslide risk assessment.Previous studies rarely contribute to the probabilistic analysis of slope stability under rainfall with reinforcement.A new method is suggested for reliability analysis of soil slopes stabilized with piles under rainfall.First,an efficient numerical model is exploited for slope stability analysis,where two types of slope failure modes,i.e.,plastic flow and local failure are considered.To address the blocking effect of piles during seepage analysis,the equivalent hydraulic conductivity of the pile area is estimated according to the effective medium theory.The stabilizing force of piles is investigated by an analytical approach.For saving computational effort,the response surface is established based on a multi-class classification model to predict two types of slope failure modes.Finally,uncertainties in soil parameters and rainfall events are both modelled,and the failure probability of soil slopes within a given time period is assessed through Monte Carlo simulation.An illustrative example is used to demonstrate the performance of the suggested method.It is found that the slope is mainly controlled by local failure.As the pile spacing increases,the likelihood of plastic flow significantly increases.As the piles are located near the slope crest,plastic flow is effectively prevented and the slope is better stabilized against rainfall.If rainfall uncertainties are not considered,the slope failure probability is significantly overestimated.Overall,this study can provide a useful guidance for the design of pile-stabilized slopes against rainfall infiltration.展开更多
The swinging-loading process is essential for automatic artillery loading systems.This study focuses on the problems of reliability analysis that affect swinging-loading positioning accuracy.A dynamic model for a mult...The swinging-loading process is essential for automatic artillery loading systems.This study focuses on the problems of reliability analysis that affect swinging-loading positioning accuracy.A dynamic model for a multi degree-of-freedom swinging-loading-integrated rigid-flexible coupling system is established.This model is based on the identification of key parameters and platform experiments.Based on the spatial geometric relationship between the breech and loader during modular charge transfer and the possible maximum interference depth of the modular charge,a new failure criterion for estimating the reliability of swinging-loading positioning accuracy is proposed.Considering the uncertainties in the operation of the pendulum loader,the direct probability integration method is introduced to analyze the reliability of the swinging-loading positioning accuracy under three different charge numbers.The results indicate that under two and four charges,the swinging-loading process shows outstanding reliability.However,an unstable stage appears when the swinging motion occurred under six charges,with a maximum positioning failure probability of 0.0712.A comparison between the results obtained under the conventional and proposed criteria further reveals the effectiveness and necessity of the proposed criterion.展开更多
Thetraditional first-order reliability method(FORM)often encounters challengeswith non-convergence of results or excessive calculation when analyzing complex engineering problems.To improve the global convergence spee...Thetraditional first-order reliability method(FORM)often encounters challengeswith non-convergence of results or excessive calculation when analyzing complex engineering problems.To improve the global convergence speed of structural reliability analysis,an improved coati optimization algorithm(COA)is proposed in this paper.In this study,the social learning strategy is used to improve the coati optimization algorithm(SL-COA),which improves the convergence speed and robustness of the newheuristic optimization algorithm.Then,the SL-COAis comparedwith the latest heuristic optimization algorithms such as the original COA,whale optimization algorithm(WOA),and osprey optimization algorithm(OOA)in the CEC2005 and CEC2017 test function sets and two engineering optimization design examples.The optimization results show that the proposed SL-COA algorithm has a high competitiveness.Secondly,this study introduces the SL-COA algorithm into the MPP(Most Probable Point)search process based on FORM and constructs a new reliability analysis method.Finally,the proposed reliability analysis method is verified by four mathematical examples and two engineering examples.The results show that the proposed SL-COA-assisted FORM exhibits fast convergence and avoids premature convergence to local optima as demonstrated by its successful application to problems such as composite cylinder design and support bracket analysis.展开更多
In the structural reliability analysis,the first-order reliability method(FORM)often yields significant errors when addressing nonlinear problems.Although the second-order reliability method(SORM)can provide higher ac...In the structural reliability analysis,the first-order reliability method(FORM)often yields significant errors when addressing nonlinear problems.Although the second-order reliability method(SORM)can provide higher accuracy,the additional computation of the Hessian matrix leads to lower computational efficiency.Additionally,when the dimensionality of the random variables is high,the approximation formula of SORM can result in larger errors.To address these issues,a structural reliability analysis method based on Kriging and spherical cap area integral is proposed.Firstly,this method integrates FORM with the quasi-Newton algorithm Broyden-Fletcher-Goldfarb-Shanno(BFGS),trains the Kriging model by using sample points from the algorithm’s iteration process,and combines the Kriging model with gradient information to approximate the Hessian matrix.Then,the failure surface is approximated as a rotating paraboloid,utilizing the spherical cap to replace the complex surface.For the n-dimensional case,the hyperspherical cap area expression is combined with the integral method to calculate the failure probability.Finally,the method is validated through three examples,demonstrating improved computational accuracy and efficiency compared to traditional methods.展开更多
The study aims to determine the validity and reliability of the Wechsler Preschool and Primary Scale of Intelligence–Third Edition(WPPSI-III)scores in a sample of kindergarten and lower primary pupils from Khartoum S...The study aims to determine the validity and reliability of the Wechsler Preschool and Primary Scale of Intelligence–Third Edition(WPPSI-III)scores in a sample of kindergarten and lower primary pupils from Khartoum State,Sudan.It also aims to examine whether test’s factor structure in this sample replicated that of the original WPPSI-III.The study sample consisted of 384 kindergarten and primary school children in Khartoum State(females=50%mean age=4.14,SD=1.37),selected using stratified random sampling across its seven localities:Khartoum,Jebel Awliya,Khartoum Bahri,East Nile,Omdurman,Ombada,Karari.For concurrent validation,the children additionally completed the Goodenough Draw-a-Man Test,and the Colored Progressive Matrices.WPPSI-III scores demonstrated high internal consistency across the subtest items.Confirmatory factor analysis indicators for total,verbal,and performance intelligence were all excellent.The scale also showed weak to strong score stability ranging from 0.25(weak)to 0.88(strong)based on the Spearman-Brown equation,0.25 to 0.75 based on the Guttman split-half method.The Cronbach’s alpha coefficient scores ranged from 0.54 to 0.93.The WPPSI-III and Goodenough Draw-a-Man Test scores concurrent validity scores were poor(0.05)to modest(0.31),and while those with the Colored Progressive Matrices test were poor(r=0.04–0.18).Thesefindings provide evidence to suggest that the WPPSI-III is appropriate for research use with kindergarten and lower primary school students in Khartoum State,Sudan.展开更多
To study the durability of concrete in harsh environments in Northwest China,concrete was prepared with various durability-improving materials such as concrete anti-erosion inhibitor(SBT-TIA),acrylate polymer(AP),supe...To study the durability of concrete in harsh environments in Northwest China,concrete was prepared with various durability-improving materials such as concrete anti-erosion inhibitor(SBT-TIA),acrylate polymer(AP),super absorbent resin(SAP).The erosion mode and internal deterioration mechanism under salt freeze-thaw cycle and dry-wet cycle were explored.The results show that the addition of enhancing materials can effectively improve the resistance of concrete to salt freezing and sulfate erosion:the relevant indexes of concrete added with X-AP and T-AP are improved after salt freeze-thaw cycles;concrete added with SBTTIA shows optimal sulfate corrosion resistance;and concrete added with AP displays the best resistance to salt freezing.Microanalysis shows that the increase in the number of cycles decreases the generation of internal hydration products and defects in concrete mixed with enhancing materials and improves the related indexes.Based on the Wiener model analysis,the reliability of concrete with different lithologies and enhancing materials is improved,which may provide a reference for the application of manufactured sand concrete and enhancing materials in Northwest China,especially for the study of the improvement effects and mechanism of enhancing materials on the performance of concrete.展开更多
Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine...Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine’s Conservation Model as the theoretical framework,an item pool was formed through literature review,and the initial draft of the scale was refined through two rounds of Delphi expert consultation.A total of 200 postoperative patients were selected for item analysis,internal consistency testing,content validity,and structural validity analysis.Results:The final tool comprises four dimensions:energy conservation,structural integrity,personal integrity,and social integrity,with a total of 24 items.It demonstrates good content validity(I-CVI 0.82-1.00,S-CVI/Ave 0.95,S-CVI/UA 0.87)and excellent internal consistency(Cronbach’sαfor the overall scale was 0.934).Exploratory factor analysis revealed a KMO value of 0.931,Bartlett’s test of sphericityχ^(2)=4147.853(p<0.001),and four common factors were extracted,accounting for a cumulative variance contribution rate of 64.345%,indicating ideal structural validity.Conclusion:The results indicate that the assessment tool has good reliability and validity and can systematically evaluate postoperative wound healing,providing a scientific basis for clinical individualized nursing interventions.展开更多
Thermal Protection System(TPS)with thick tiles,low thermal conductivity,and a short re-entry stage stands as a critical element within reusable aircraft,whose reliability is related to the function and changes with th...Thermal Protection System(TPS)with thick tiles,low thermal conductivity,and a short re-entry stage stands as a critical element within reusable aircraft,whose reliability is related to the function and changes with their physical properties,external conditions,and degradation.Meanwhile,due to the limitation of testing resources,epistemic uncertainties stemming from the small samples are present in TPS reliability modeling.However,current TPS reliability modeling methods face challenges in characterizing the relationships among reliability and physical properties,external conditions,degradation,and epistemic uncertainties.Therefore,under the framework of belief reliability theory,a TPS reliability model is constructed,which takes into account the physical principle,external conditions,performance degradation,and epistemic uncertainties.A reliability simulation algorithm is proposed to calculate TPS reliability.Through a case study and comparison analysis,the proposed method is validated as more effective than the existing method.Additionally,reliability sensitivity analysis is conducted to identify the sensitive factors of reliability under the condition of small samples,through which suggestions are provided for TPS functional design and improvement.展开更多
The utilization of high-strength steel bars(HSSB)within concrete structures demonstrates significant advantages in material conservation and mechanical performance enhancement.Nevertheless,existing design codes exhibi...The utilization of high-strength steel bars(HSSB)within concrete structures demonstrates significant advantages in material conservation and mechanical performance enhancement.Nevertheless,existing design codes exhibit limitations in addressing the distinct statistical characteristics of HSSB,particularly regarding strength design parameters.For instance,GB50010-2010 fails to specify design strength values for reinforcement exceeding 600 MPa,creating technical barriers for advancing HSSB implementation.This study systematically investigates the reliability of eccentric compression concrete columns reinforced with 600 MPa-grade HSSB through high-order moment method analysis.Material partial factors were calibrated against target reliability indices prescribed by GB50068-2018,incorporating critical variables including live-to-dead load ratios,design methodologies,and service conditions.The findings show that the value of k significantly affects the calibration of material partial factors,impacting the reliability of bearing capacity.Considering various k values and target reliability indices,it is recommended that the material partialfactorbe setat1.15,implyingthatthedesignstrengthfor600MPahigh-strengthsteelbars shouldbe considered as 522 MPa.For safety levels I and II,load adjustment factors of 1.1 and 0.9,respectively,may be applied.展开更多
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.展开更多
Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'...Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.展开更多
This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency...This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency,severity,and alignment with human scoring criteria.Results show that AI exhibits high self-consistency and adapts effectively to different scoring roles(e.g.,teacher vs.highstakes rater).However,AI scores were more lenient than human raters and demonstrated divergent evaluation focuses—prioritizing narrative coherence and emotional depth,while teachers emphasized linguistic accuracy and richness of detail.The findings suggest AI’s potential as a supplementary assessment tool,offering rapid,holistic feedback,but highlight the need for further calibration to align with educational standards.Implications include exploring hybrid evaluation models that leverage the strengths of both AI and human raters to achieve more equitable,efficient,and pedagogically meaningful writing assessments.展开更多
A stochastic predator-prey system with Markov switching is explored.We have developed a new chasing technique to efficiently solve the Fokker-Planck-Kolmogorov and backward Kolmogorov equations.Dynamic balance and rel...A stochastic predator-prey system with Markov switching is explored.We have developed a new chasing technique to efficiently solve the Fokker-Planck-Kolmogorov and backward Kolmogorov equations.Dynamic balance and reliability of the switching system are evaluated via stationary probability density function and first-passage failure theory,taking into account factors such as switching frequencies,noise intensities,and initial conditions.Results reveal that Markov switching leads to stochastic P-bifurcation,enhancing dynamic balance and reducing white-noise-induced oscillations.But frequent switching can heighten initial value dependence,harming reliability.Further,the influence of the subsystem on the switching system is not proportional to its action probabilities.Monte Carlo simulations validate the findings,offering an in-depth exploration of these dynamics.展开更多
In this work,we demonstrated the InSnO(ITO)TFTs passivated with SiO_(2)via the PECVD process compatible with large-area production for the first time.The passivated ITO TFTs with various channel thicknesses(t_(ch)=4,5...In this work,we demonstrated the InSnO(ITO)TFTs passivated with SiO_(2)via the PECVD process compatible with large-area production for the first time.The passivated ITO TFTs with various channel thicknesses(t_(ch)=4,5,6 nm)exhibit excellent electrical performance and superior uniformity.The reliability properties of ITO TFTs were evaluated in detail under positive bias stress(PBS)conditions before and after passivation.Compared to the devices without passivation,the passivated devices have only 50%threshold voltage degradation(ΔV_(th))and 50%newly generated traps due to excellent isolation of the ambient atmosphere.The negligible performance degradation of ITO TFTs with passivation during negative bias stress(NBS)and negative bias temperature stress(NBTS)verifies the outstanding immunity to the water vapor of the SiO_(2)passivation layer.Overall,the ITO TFT with the t_(ch)of 6 nm and with SiO_(2)passivation exhibits the best performance in terms of electrical properties,uniformity,and reliability,which is promising in large-area production.展开更多
The Savitzky-Golay(SG)filter,which employs polynomial least-squares approximations to smooth data and estimate derivatives,is widely used for processing noisy data.However,noise suppression by the SG filter is recogni...The Savitzky-Golay(SG)filter,which employs polynomial least-squares approximations to smooth data and estimate derivatives,is widely used for processing noisy data.However,noise suppression by the SG filter is recognized to be limited at data boundaries and high frequencies,which can significantly reduce the signal-to-noise ratio(SNR).To solve this problem,a novel method synergistically integrating Principal Component Analysis(PCA)with SG filtering is proposed in this paper.This approach avoids the is-sue of excessive smoothing associated with larger window sizes.The proposed PCA-SG filtering algorithm was applied to a CO gas sensing system based on Cavity Ring-Down Spectroscopy(CRDS).The perform-ance of the PCA-SG filtering algorithm is demonstrated through comparison with Moving Average Filtering(MAF),Wavelet Transformation(WT),Kalman Filtering(KF),and the SG filter.The results demonstrate that the proposed algorithm exhibits superior noise reduction capabilities compared to the other algorithms evaluated.The SNR of the ring-down signal was improved from 11.8612 dB to 29.0913 dB,and the stand-ard deviation of the extracted ring-down time constant was reduced from 0.037μs to 0.018μs.These results confirm that the proposed PCA-SG filtering algorithm effectively improves the smoothness of the ring-down curve data,demonstrating its feasibility.展开更多
Objective:To evaluate the global,regional,and national burden and determinants of Acute Respiratory Infections(ARIs)among children and adolescents from 1990 to 2021.Methods:We analysed ARI mortality and disability-adj...Objective:To evaluate the global,regional,and national burden and determinants of Acute Respiratory Infections(ARIs)among children and adolescents from 1990 to 2021.Methods:We analysed ARI mortality and disability-adjusted life years(DALYs),stratified by age,sex,and economic development level based on data retrieved from the Global Burden of Disease study 2021.Decomposition and frontier analyses were employed to identify key drivers of burden variation and visualize potential reductions based on development levels.Results:Between 1990 and 2021,the global burden of ARIs showed a significant decline in both achievable age-standardized DALYs rate and age-standardized mortality rates(EAPC=-3.87 and-3.81,respectively).Different age groups and sex witnessed different levels of ARI burden,males experienced heavier burden than females and the 0-4 years-old group experienced heavier burden than other study age groups.Most of the 204 countries and territories experienced a downward trend of ARI burden,with slight increases observed only in Lesotho and Dominica.A negative correlation was found between the Socio-demographic Index and ARI burden.Decomposition analysis indicated that the significant decreases in deaths and DALYs were primarily driven by epidemiological changes.Conclusions:The global burden of ARIs among children and adolescents has declined over the past three decades,but substantial regional disparities persist.Targeted public health strategies are needed to address the continued ARI burden in high-risk regions and vulnerable age groups.展开更多
基金supported by the Major Program of National Natural Science Foundation of China(Grant No.42090055)the National Key ScientificInstruments and Equipment Development Projects of China(Grant No.41827808)the National Nature Science Foundation of China(Grant No.42207216).
文摘Reservoir-induced landslides in China's Three Gorges Reservoir area are prone to tensile cracks due to the influenceof their own weight and fluctuationsin water levels.The presence of cracks indicates that the tensile stress in the area has exceeded the tensile strength of the soil,leading to local instability.To explore the impact of tensile failure behavior on the stability and failure modes of reservoir landslides,the Huangtupo Riverside Slump#1 is taken as a case study.By considering local tensile failure,potential tensile cracks are incorporated into the analysis via the limit equilibrium method and reliability theory.The reliability of landslides under different tensile failure scenarios is quantified.Strain-softening characteristics of the soil are combined to further analyze the failure transmission path of the landslide.Finally,these potential failure modes were validated through physical model tests.The results show that cracks developing at rear positions reduce the stability of the slope and increase the probability of instability.During the destruction process,retrogressive failures with multiple sliding surfaces are likely to occur.However,tensile failure at the forefront reduces the likelihood of an individual slide mass descending.Progressive failure results in both regular and skip transmission patterns.Additionally,cracks and water level changes can also lead to shifts in the positions of the most dangerous blocks.Therefore,in practical landslide analysis and prevention,it is necessary to consider local tensile damage and identify potential tensile crack locations in advance to optimize prevention measures and accurately evaluate landslide risk.
基金National Natural Science Foundation of China(No.52375236)Fundamental Research Funds for the Central Universities of China(No.23D110316)。
文摘In reliability analyses,the absence of a priori information on the most probable point of failure(MPP)may result in overlooking critical points,thereby leading to biased assessment outcomes.Moreover,second-order reliability methods exhibit limited accuracy in highly nonlinear scenarios.To overcome these challenges,a novel reliability analysis strategy based on a multimodal differential evolution algorithm and a hypersphere integration method is proposed.Initially,the penalty function method is employed to reformulate the MPP search problem as a conditionally constrained optimization task.Subsequently,a differential evolution algorithm incorporating a population delineation strategy is utilized to identify all MPPs.Finally,a paraboloid equation is constructed based on the curvature of the limit-state function at the MPPs,and the failure probability of the structure is calculated by using the hypersphere integration method.The localization effectiveness of the MPPs is compared through multiple numerical cases and two engineering examples,with accuracy comparisons of failure probabilities against the first-order reliability method(FORM)and the secondorder reliability method(SORM).The results indicate that the method effectively identifies existing MPPs and achieves higher solution precision.
基金supported by Istanbul Technical University(Project No.45698)supported through the“Young Researchers’Career Development Project-training of doctoral students”of the Croatian Science Foundation.
文摘This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.
基金The National Key R&D Program Projects(Grant No.2022YFC2803601)the Natural Science Foundation of Shandong Province(Grant No.ZR2021YQ29)+1 种基金the Natural Science Foundation of Heilongjiang Province(Grant No.YQ2024E036)the Taishan Scholars Project(Grant No.tsqn202312317).
文摘Autonomous Underwater Vehicles(AUVs)are pivotal for deep-sea exploration and resource exploitation,yet their reliability in extreme underwater environments remains a critical barrier to widespread deployment.Through systematic analysis of 150 peer-reviewed studies employing mixed-methods research,this review yields three principal advancements to the reliability analysis of AUVs.First,based on the hierarchical functional division of AUVs into six subsystems(propulsion system,navigation system,communication system,power system,environmental detection system,and emergency system),this study systematically identifies the primary failure modes and potential failure causes of each subsystem,providing theoretical support for fault diagnosis and reliability optimization.Subsequently,a comprehensive review of AUV reliability analysis methods is conducted from three perspectives:analytical methods,simulated methods,and surrogate model methods.The applicability and limitations of each method are critically analyzed to offer insights into their suitability for engineering applications.Finally,the study highlights key challenges and research hotpots in AUV reliability analysis,including reliability analysis under limited data,AI-driven reliability analysis,and human reliability analysis.Furthermore,the potential of multi-sensor data fusion,edge computing,and advanced materials in enhancing AUV environmental adaptability and reliability is explored.
基金supported by the National Key Research and Development Program of China(Grant No.2021YFB2600504)the National Natural Science Foundation of China(Grant No.42072302)the Postdoctoral Fellowship Program of CPSF(Grant No.GZB20240533).
文摘Reliability analysis of soil slopes under rainfall is an important task for landslide risk assessment.Previous studies rarely contribute to the probabilistic analysis of slope stability under rainfall with reinforcement.A new method is suggested for reliability analysis of soil slopes stabilized with piles under rainfall.First,an efficient numerical model is exploited for slope stability analysis,where two types of slope failure modes,i.e.,plastic flow and local failure are considered.To address the blocking effect of piles during seepage analysis,the equivalent hydraulic conductivity of the pile area is estimated according to the effective medium theory.The stabilizing force of piles is investigated by an analytical approach.For saving computational effort,the response surface is established based on a multi-class classification model to predict two types of slope failure modes.Finally,uncertainties in soil parameters and rainfall events are both modelled,and the failure probability of soil slopes within a given time period is assessed through Monte Carlo simulation.An illustrative example is used to demonstrate the performance of the suggested method.It is found that the slope is mainly controlled by local failure.As the pile spacing increases,the likelihood of plastic flow significantly increases.As the piles are located near the slope crest,plastic flow is effectively prevented and the slope is better stabilized against rainfall.If rainfall uncertainties are not considered,the slope failure probability is significantly overestimated.Overall,this study can provide a useful guidance for the design of pile-stabilized slopes against rainfall infiltration.
文摘The swinging-loading process is essential for automatic artillery loading systems.This study focuses on the problems of reliability analysis that affect swinging-loading positioning accuracy.A dynamic model for a multi degree-of-freedom swinging-loading-integrated rigid-flexible coupling system is established.This model is based on the identification of key parameters and platform experiments.Based on the spatial geometric relationship between the breech and loader during modular charge transfer and the possible maximum interference depth of the modular charge,a new failure criterion for estimating the reliability of swinging-loading positioning accuracy is proposed.Considering the uncertainties in the operation of the pendulum loader,the direct probability integration method is introduced to analyze the reliability of the swinging-loading positioning accuracy under three different charge numbers.The results indicate that under two and four charges,the swinging-loading process shows outstanding reliability.However,an unstable stage appears when the swinging motion occurred under six charges,with a maximum positioning failure probability of 0.0712.A comparison between the results obtained under the conventional and proposed criteria further reveals the effectiveness and necessity of the proposed criterion.
基金funded by the National Key Research and Development Program(Grant No.2022YFB3706904).
文摘Thetraditional first-order reliability method(FORM)often encounters challengeswith non-convergence of results or excessive calculation when analyzing complex engineering problems.To improve the global convergence speed of structural reliability analysis,an improved coati optimization algorithm(COA)is proposed in this paper.In this study,the social learning strategy is used to improve the coati optimization algorithm(SL-COA),which improves the convergence speed and robustness of the newheuristic optimization algorithm.Then,the SL-COAis comparedwith the latest heuristic optimization algorithms such as the original COA,whale optimization algorithm(WOA),and osprey optimization algorithm(OOA)in the CEC2005 and CEC2017 test function sets and two engineering optimization design examples.The optimization results show that the proposed SL-COA algorithm has a high competitiveness.Secondly,this study introduces the SL-COA algorithm into the MPP(Most Probable Point)search process based on FORM and constructs a new reliability analysis method.Finally,the proposed reliability analysis method is verified by four mathematical examples and two engineering examples.The results show that the proposed SL-COA-assisted FORM exhibits fast convergence and avoids premature convergence to local optima as demonstrated by its successful application to problems such as composite cylinder design and support bracket analysis.
基金National Natural Science Foundation of China(No.52375236)Fundamental Research Funds for the Central Universities,China(No.23D110316)。
文摘In the structural reliability analysis,the first-order reliability method(FORM)often yields significant errors when addressing nonlinear problems.Although the second-order reliability method(SORM)can provide higher accuracy,the additional computation of the Hessian matrix leads to lower computational efficiency.Additionally,when the dimensionality of the random variables is high,the approximation formula of SORM can result in larger errors.To address these issues,a structural reliability analysis method based on Kriging and spherical cap area integral is proposed.Firstly,this method integrates FORM with the quasi-Newton algorithm Broyden-Fletcher-Goldfarb-Shanno(BFGS),trains the Kriging model by using sample points from the algorithm’s iteration process,and combines the Kriging model with gradient information to approximate the Hessian matrix.Then,the failure surface is approximated as a rotating paraboloid,utilizing the spherical cap to replace the complex surface.For the n-dimensional case,the hyperspherical cap area expression is combined with the integral method to calculate the failure probability.Finally,the method is validated through three examples,demonstrating improved computational accuracy and efficiency compared to traditional methods.
基金The authors extend their appreciation to the Ongoing Research Funding Program,number(ORF2025R705),King Saud University,Riyadh,Saudi Arabia,for funding this work.
文摘The study aims to determine the validity and reliability of the Wechsler Preschool and Primary Scale of Intelligence–Third Edition(WPPSI-III)scores in a sample of kindergarten and lower primary pupils from Khartoum State,Sudan.It also aims to examine whether test’s factor structure in this sample replicated that of the original WPPSI-III.The study sample consisted of 384 kindergarten and primary school children in Khartoum State(females=50%mean age=4.14,SD=1.37),selected using stratified random sampling across its seven localities:Khartoum,Jebel Awliya,Khartoum Bahri,East Nile,Omdurman,Ombada,Karari.For concurrent validation,the children additionally completed the Goodenough Draw-a-Man Test,and the Colored Progressive Matrices.WPPSI-III scores demonstrated high internal consistency across the subtest items.Confirmatory factor analysis indicators for total,verbal,and performance intelligence were all excellent.The scale also showed weak to strong score stability ranging from 0.25(weak)to 0.88(strong)based on the Spearman-Brown equation,0.25 to 0.75 based on the Guttman split-half method.The Cronbach’s alpha coefficient scores ranged from 0.54 to 0.93.The WPPSI-III and Goodenough Draw-a-Man Test scores concurrent validity scores were poor(0.05)to modest(0.31),and while those with the Colored Progressive Matrices test were poor(r=0.04–0.18).Thesefindings provide evidence to suggest that the WPPSI-III is appropriate for research use with kindergarten and lower primary school students in Khartoum State,Sudan.
基金Funded by the National Natural Science Foundation of China(No.52178216)the Research on the Durability and Application of High-performance Concrete for Highway Engineering in the Cold and Arid Salt Areas of Northwest China(No.2022-24)the Construction Project of the Scientific Research Platform of Provincial Enterprises Supported by the Capital Operating Budget of Gansu Province(No.2023GZ018)。
文摘To study the durability of concrete in harsh environments in Northwest China,concrete was prepared with various durability-improving materials such as concrete anti-erosion inhibitor(SBT-TIA),acrylate polymer(AP),super absorbent resin(SAP).The erosion mode and internal deterioration mechanism under salt freeze-thaw cycle and dry-wet cycle were explored.The results show that the addition of enhancing materials can effectively improve the resistance of concrete to salt freezing and sulfate erosion:the relevant indexes of concrete added with X-AP and T-AP are improved after salt freeze-thaw cycles;concrete added with SBTTIA shows optimal sulfate corrosion resistance;and concrete added with AP displays the best resistance to salt freezing.Microanalysis shows that the increase in the number of cycles decreases the generation of internal hydration products and defects in concrete mixed with enhancing materials and improves the related indexes.Based on the Wiener model analysis,the reliability of concrete with different lithologies and enhancing materials is improved,which may provide a reference for the application of manufactured sand concrete and enhancing materials in Northwest China,especially for the study of the improvement effects and mechanism of enhancing materials on the performance of concrete.
基金Sichuan Provincial Nursing Research Project of the Sichuan Nursing Association in 2023(Project No.:H23028)。
文摘Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine’s Conservation Model as the theoretical framework,an item pool was formed through literature review,and the initial draft of the scale was refined through two rounds of Delphi expert consultation.A total of 200 postoperative patients were selected for item analysis,internal consistency testing,content validity,and structural validity analysis.Results:The final tool comprises four dimensions:energy conservation,structural integrity,personal integrity,and social integrity,with a total of 24 items.It demonstrates good content validity(I-CVI 0.82-1.00,S-CVI/Ave 0.95,S-CVI/UA 0.87)and excellent internal consistency(Cronbach’sαfor the overall scale was 0.934).Exploratory factor analysis revealed a KMO value of 0.931,Bartlett’s test of sphericityχ^(2)=4147.853(p<0.001),and four common factors were extracted,accounting for a cumulative variance contribution rate of 64.345%,indicating ideal structural validity.Conclusion:The results indicate that the assessment tool has good reliability and validity and can systematically evaluate postoperative wound healing,providing a scientific basis for clinical individualized nursing interventions.
基金supported by the steady supports scientific research of Key Laboratory of Defense Science and Technology,China(No.WDZC20220105)the National Natural Science Foundation of China(Nos.51775020,62073009,U20B2002)the Science Challenge Project,China(No.TZ2018007)。
文摘Thermal Protection System(TPS)with thick tiles,low thermal conductivity,and a short re-entry stage stands as a critical element within reusable aircraft,whose reliability is related to the function and changes with their physical properties,external conditions,and degradation.Meanwhile,due to the limitation of testing resources,epistemic uncertainties stemming from the small samples are present in TPS reliability modeling.However,current TPS reliability modeling methods face challenges in characterizing the relationships among reliability and physical properties,external conditions,degradation,and epistemic uncertainties.Therefore,under the framework of belief reliability theory,a TPS reliability model is constructed,which takes into account the physical principle,external conditions,performance degradation,and epistemic uncertainties.A reliability simulation algorithm is proposed to calculate TPS reliability.Through a case study and comparison analysis,the proposed method is validated as more effective than the existing method.Additionally,reliability sensitivity analysis is conducted to identify the sensitive factors of reliability under the condition of small samples,through which suggestions are provided for TPS functional design and improvement.
基金supported by grants from the Natural Science Foundation of Fujian Province(Grant No.2022J05184).
文摘The utilization of high-strength steel bars(HSSB)within concrete structures demonstrates significant advantages in material conservation and mechanical performance enhancement.Nevertheless,existing design codes exhibit limitations in addressing the distinct statistical characteristics of HSSB,particularly regarding strength design parameters.For instance,GB50010-2010 fails to specify design strength values for reinforcement exceeding 600 MPa,creating technical barriers for advancing HSSB implementation.This study systematically investigates the reliability of eccentric compression concrete columns reinforced with 600 MPa-grade HSSB through high-order moment method analysis.Material partial factors were calibrated against target reliability indices prescribed by GB50068-2018,incorporating critical variables including live-to-dead load ratios,design methodologies,and service conditions.The findings show that the value of k significantly affects the calibration of material partial factors,impacting the reliability of bearing capacity.Considering various k values and target reliability indices,it is recommended that the material partialfactorbe setat1.15,implyingthatthedesignstrengthfor600MPahigh-strengthsteelbars shouldbe considered as 522 MPa.For safety levels I and II,load adjustment factors of 1.1 and 0.9,respectively,may be applied.
基金supported by Qingdao Key Medical and Health Discipline ProjectThe Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
文摘Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.
文摘Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.
文摘This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency,severity,and alignment with human scoring criteria.Results show that AI exhibits high self-consistency and adapts effectively to different scoring roles(e.g.,teacher vs.highstakes rater).However,AI scores were more lenient than human raters and demonstrated divergent evaluation focuses—prioritizing narrative coherence and emotional depth,while teachers emphasized linguistic accuracy and richness of detail.The findings suggest AI’s potential as a supplementary assessment tool,offering rapid,holistic feedback,but highlight the need for further calibration to align with educational standards.Implications include exploring hybrid evaluation models that leverage the strengths of both AI and human raters to achieve more equitable,efficient,and pedagogically meaningful writing assessments.
基金Project supported by the National Natural Science Foundation of China(Grant No.12472033)。
文摘A stochastic predator-prey system with Markov switching is explored.We have developed a new chasing technique to efficiently solve the Fokker-Planck-Kolmogorov and backward Kolmogorov equations.Dynamic balance and reliability of the switching system are evaluated via stationary probability density function and first-passage failure theory,taking into account factors such as switching frequencies,noise intensities,and initial conditions.Results reveal that Markov switching leads to stochastic P-bifurcation,enhancing dynamic balance and reducing white-noise-induced oscillations.But frequent switching can heighten initial value dependence,harming reliability.Further,the influence of the subsystem on the switching system is not proportional to its action probabilities.Monte Carlo simulations validate the findings,offering an in-depth exploration of these dynamics.
基金supported in part by the National Natural Science Foundation of China(62404110,62274033)Natural Science Foundation of Jiangsu Province(BK20221453)+1 种基金Fundamental Research Funds for the Central UniversitiesNatural Science Research Start-up Foundation of Recruiting Talents of Nanjing University of Posts and Telecommunications(NY223159)。
文摘In this work,we demonstrated the InSnO(ITO)TFTs passivated with SiO_(2)via the PECVD process compatible with large-area production for the first time.The passivated ITO TFTs with various channel thicknesses(t_(ch)=4,5,6 nm)exhibit excellent electrical performance and superior uniformity.The reliability properties of ITO TFTs were evaluated in detail under positive bias stress(PBS)conditions before and after passivation.Compared to the devices without passivation,the passivated devices have only 50%threshold voltage degradation(ΔV_(th))and 50%newly generated traps due to excellent isolation of the ambient atmosphere.The negligible performance degradation of ITO TFTs with passivation during negative bias stress(NBS)and negative bias temperature stress(NBTS)verifies the outstanding immunity to the water vapor of the SiO_(2)passivation layer.Overall,the ITO TFT with the t_(ch)of 6 nm and with SiO_(2)passivation exhibits the best performance in terms of electrical properties,uniformity,and reliability,which is promising in large-area production.
文摘The Savitzky-Golay(SG)filter,which employs polynomial least-squares approximations to smooth data and estimate derivatives,is widely used for processing noisy data.However,noise suppression by the SG filter is recognized to be limited at data boundaries and high frequencies,which can significantly reduce the signal-to-noise ratio(SNR).To solve this problem,a novel method synergistically integrating Principal Component Analysis(PCA)with SG filtering is proposed in this paper.This approach avoids the is-sue of excessive smoothing associated with larger window sizes.The proposed PCA-SG filtering algorithm was applied to a CO gas sensing system based on Cavity Ring-Down Spectroscopy(CRDS).The perform-ance of the PCA-SG filtering algorithm is demonstrated through comparison with Moving Average Filtering(MAF),Wavelet Transformation(WT),Kalman Filtering(KF),and the SG filter.The results demonstrate that the proposed algorithm exhibits superior noise reduction capabilities compared to the other algorithms evaluated.The SNR of the ring-down signal was improved from 11.8612 dB to 29.0913 dB,and the stand-ard deviation of the extracted ring-down time constant was reduced from 0.037μs to 0.018μs.These results confirm that the proposed PCA-SG filtering algorithm effectively improves the smoothness of the ring-down curve data,demonstrating its feasibility.
文摘Objective:To evaluate the global,regional,and national burden and determinants of Acute Respiratory Infections(ARIs)among children and adolescents from 1990 to 2021.Methods:We analysed ARI mortality and disability-adjusted life years(DALYs),stratified by age,sex,and economic development level based on data retrieved from the Global Burden of Disease study 2021.Decomposition and frontier analyses were employed to identify key drivers of burden variation and visualize potential reductions based on development levels.Results:Between 1990 and 2021,the global burden of ARIs showed a significant decline in both achievable age-standardized DALYs rate and age-standardized mortality rates(EAPC=-3.87 and-3.81,respectively).Different age groups and sex witnessed different levels of ARI burden,males experienced heavier burden than females and the 0-4 years-old group experienced heavier burden than other study age groups.Most of the 204 countries and territories experienced a downward trend of ARI burden,with slight increases observed only in Lesotho and Dominica.A negative correlation was found between the Socio-demographic Index and ARI burden.Decomposition analysis indicated that the significant decreases in deaths and DALYs were primarily driven by epidemiological changes.Conclusions:The global burden of ARIs among children and adolescents has declined over the past three decades,but substantial regional disparities persist.Targeted public health strategies are needed to address the continued ARI burden in high-risk regions and vulnerable age groups.
