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Changes in retinal capillary density in female with type 2 diabetes and gestational diabetes——an analysis based on OCTA technology
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作者 Jing Zhang Yao Yu +11 位作者 Xian-Mei Zhou Xuan Liao Jin-Yu Hu Qian Ling Jie Zou Cheng Chen Liang-Qi He Hong Wei Xu Chen Yi-Xin Wang Yi Shao Rui-Man Li 《International Journal of Ophthalmology(English edition)》 2025年第3期435-448,共14页
AIM:To evaluate alterations in conjunctival vascular density(CVD)and macular capillary density(MCD)in female patients with type 2 diabetes mellitus(T2DM)and gestational diabetes mellitus(GDM)using optical coherence to... AIM:To evaluate alterations in conjunctival vascular density(CVD)and macular capillary density(MCD)in female patients with type 2 diabetes mellitus(T2DM)and gestational diabetes mellitus(GDM)using optical coherence tomography angiography(OCTA).METHODS:A total of 60 female participants were recruited,comprising 20 patients with T2DM,20 patients with GDM,and 20 healthy age-matched controls(HCs).OCTA was used to assess superficial and deep retinal and conjunctival capillary plexuses.Subsequently,changes in MCD were analyzed using a circular segmentation method(C1-C6),a hemispheric quadrant segmentation method[superior right(SR),superior left(SL),inferior left(IL),and inferior right(IR)],and the early treatment diabetic retinopathy study(ETDRS)segmentation method(S,I,R,L).RESULTS:OCTA unequivocally demonstrated that the variations in CVD among HCs,T2DM,and GDM groups were statistically significant(P<0.001).In the superficial retinal capillary plexus(sRCP),significant differences were observed in the densities of total microvascular(TMI),microvasculature(MIR),and macrovascular(MAR)between patients with T2DM and HCs(P<0.05).Furthermore,the GDM group exhibited a more substantial reduction in MIR density compared to the T2DM group(P<0.01).In the deep retinal capillary plexus(dRCP),significant differences in the densities of TMI and MIR were identified between the T2DM group and HCs(P<0.05),with a notable difference in TMI density also observed between the GDM and T2DM groups(P<0.01).In the receiver operating characteristic(ROC)curve analysis,the area under the ROC curve(AUC)for TMI in sRCP between the T2DM group and HCs was 0.975,with a 95%confidence interval(CI)of 0.941–1.The AUC for MIR was highest in dRCP,with an AUC value of 0.914 and a 95%CI ranging from 0.847 to 0.981.In comparing the GDM and T2DM groups,the AUC for I region was maximized in sRCP,achieving a value of 0.978 with a 95%CI of 0.953–1.Additionally,the AUC for R region was maximized in dRCP,reaching a value of 0.99 with a 95%CI of 0.975 to 1.CONCLUSION:The sRCP and dRCP densities show higher diagnostic sensitivity for T2DM and GDM.OCTA holds potential as a significant instrument for the early diagnosis and differentiation of T2DM and GDM. 展开更多
关键词 diabetes optical coherence tomography angiography superficial retinal capillary plexus deep retinal capillary plexus retinal region segmentation method
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A NEW DERIVATIVE FREE OPTIMIZATION METHOD BASED ON CONIC INTERPOLATION MODEL 被引量:9
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作者 倪勤 胡书华 《Acta Mathematica Scientia》 SCIE CSCD 2004年第2期281-290,共10页
In this paper, a new derivative free trust region method is developed based on the conic interpolation model for the unconstrained optimization. The conic interpolation model is built by means of the quadratic model f... In this paper, a new derivative free trust region method is developed based on the conic interpolation model for the unconstrained optimization. The conic interpolation model is built by means of the quadratic model function, the collinear scaling formula, quadratic approximation and interpolation. All the parameters in this model are determined by objective function interpolation condition. A new derivative free method is developed based upon this model and the global convergence of this new method is proved without any information on gradient. 展开更多
关键词 Derivative free optimization method conic interpolation model quadratic interpolation model trust region method unconstrained optimization
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High-temperature thermal stability of C/C−ZrC−SiC composites via region labeling method 被引量:4
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作者 Zheng PENG Chun-mao MIAO +5 位作者 Wei SUN Yong-long XU Hai-kun CHEN Yu-feng LIU Hong-bo ZHANG Xiang XIONG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2022年第10期3349-3361,共13页
To investigate the thermal stability of ceramic-matrix composites,three kinds of C/C−ZrC−SiC composites with different Zr/Si molar ratios were synthesized by reactive melt infiltration.Employing region labeling method... To investigate the thermal stability of ceramic-matrix composites,three kinds of C/C−ZrC−SiC composites with different Zr/Si molar ratios were synthesized by reactive melt infiltration.Employing region labeling method,the high-temperature thermal stability of the composites was systematically studied by changing the temperature and holding time of thermal treatment.Results show that the mass loss rate of low Si composites has a growth trend with increasing temperature,and a crystal transformation from β-SiC toα-SiC occurs in the composites.In the calibrated area,SiC phase experiences Ostwald ripening and volume change with location migration,while ZrC phase experiences a re-sintering process with diffusion.Moreover,it is found that increasing temperature has a more obvious effect on the thermal stability than extending holding time,which is mainly attributed to the faster diffusion rate of atoms. 展开更多
关键词 thermal stability ceramic-matrix composites reactive melt infiltration high-temperature thermal treatment region labeling method
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A Nonmonotone Trust Region Method for Solving Symmetric Nonlinear Equations 被引量:3
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作者 YUAN Gong-lin WEI Zeng-xin LU Xi-wen 《Chinese Quarterly Journal of Mathematics》 CSCD 2009年第4期574-584,共11页
A trust region method combining with nonmonotone technique is proposed tor solving symmetric nonlinear equations. The global convergence of the given method will be established under suitable conditions. Numerical res... A trust region method combining with nonmonotone technique is proposed tor solving symmetric nonlinear equations. The global convergence of the given method will be established under suitable conditions. Numerical results show that the method is interesting for the given problems. 展开更多
关键词 trust region method nonlinear equations nonmonotone technique
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A GLOBALLY AND SUPERLINEARLY CONVERGENT TRUST REGION METHOD FOR LC^1 OPTIMIZATION PROBLEMS 被引量:1
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作者 Zhang Liping Lai Yanlian Institute of Applied Mathematics,Academia Sinica,Beijing 100080. 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2001年第1期72-80,共9页
A new trust region algorithm for solving convex LC 1 optimization problem is presented.It is proved that the algorithm is globally convergent and the rate of convergence is superlinear under some reasonable assum... A new trust region algorithm for solving convex LC 1 optimization problem is presented.It is proved that the algorithm is globally convergent and the rate of convergence is superlinear under some reasonable assumptions. 展开更多
关键词 LC 1 optimization problem global and superlinear convergence trust region method.
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A TRUST REGION METHOD WITH A CONIC MODEL FOR NONLINEARLY CONSTRAINED OPTIMIZATION 被引量:1
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作者 Wang Chengjing 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2006年第3期263-275,共13页
Trust region methods are powerful and effective optimization methods. The conic model method is a new type of method with more information available at each iteration than standard quadratic-based methods. The adva... Trust region methods are powerful and effective optimization methods. The conic model method is a new type of method with more information available at each iteration than standard quadratic-based methods. The advantages of the above two methods can be combined to form a more powerful method for constrained optimization. The trust region subproblem of our method is to minimize a conic function subject to the linearized constraints and trust region bound. At the same time, the new algorithm still possesses robust global properties. The global convergence of the new algorithm under standard conditions is established. 展开更多
关键词 trust region method conic model constrained optimization nonlinear programming.
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A New Nonmonotone Adaptive Trust Region Method 被引量:1
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作者 Yang Zhang Quanming Ji Qinghua Zhou 《Journal of Applied Mathematics and Physics》 2021年第12期3102-3114,共13页
The trust region method plays an important role in solving optimization problems. In this paper, we propose a new nonmonotone adaptive trust region method for solving unconstrained optimization problems. Actually, we ... The trust region method plays an important role in solving optimization problems. In this paper, we propose a new nonmonotone adaptive trust region method for solving unconstrained optimization problems. Actually, we combine a popular nonmonotone technique with an adaptive trust region algorithm. The new ratio to adjusting the next trust region radius is different from the ratio in the traditional trust region methods. Under some appropriate conditions, we show that the new algorithm has good global convergence and superlinear convergence. 展开更多
关键词 Unconstrained Optimization Trust Region method Nonmonotone Technique Global Convergence Superlinear Convergence
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Projected gradient trust-region method for solving nonlinear systems with convex constraints
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作者 JIA Chun-xia ZHU De-tong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2011年第1期57-69,共13页
In this paper, a projected gradient trust region algorithm for solving nonlinear equality systems with convex constraints is considered. The global convergence results are developed in a very general setting of comput... In this paper, a projected gradient trust region algorithm for solving nonlinear equality systems with convex constraints is considered. The global convergence results are developed in a very general setting of computing trial directions by this method combining with the line search technique. Close to the solution set this method is locally Q-superlinearly convergent under an error bound assumption which is much weaker than the standard nonsingularity condition. 展开更多
关键词 Nonlinear equation trust region method projected gradient local error bound.
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A CLASS OF TRUST REGION METHODS FOR LINEAR INEQUALITY CONSTRAINED OPTIMIZATION AND ITS THEORY ANALYSIS:I.ALGORITHM AND GLOBAL CONVERGENCEXIU NAIHUA
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作者 XIU NAIHUA 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 1995年第3期287-296,共10页
A class of trust region methods for solving linear inequality constrained problems is proposed in this paper. It is shown that the algorithm is of global convergence.The algorithm uses a version of the two-sided proje... A class of trust region methods for solving linear inequality constrained problems is proposed in this paper. It is shown that the algorithm is of global convergence.The algorithm uses a version of the two-sided projection and the strategy of the unconstrained trust region methods. It keeps the good convergence properties of the unconstrained case and has the merits of the projection method. In some sense, our algorithm can be regarded as an extension and improvement of the projected type algorithm. 展开更多
关键词 Linear inequality constrained optimization trust region method global convergence
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Classification of regional agricultural structure:method and its application to China
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作者 Mou Ziping Lei Hongmei +1 位作者 Chen Guangping Li Xin 《Ecological Economy》 2008年第4期410-417,共8页
Regional agriculture is the basis of regional sustainable development, so sustainable regional agricultural development is essential to the sustainable development of the whole society and becomes the focus of global ... Regional agriculture is the basis of regional sustainable development, so sustainable regional agricultural development is essential to the sustainable development of the whole society and becomes the focus of global research. The classification of regional agricultural structure is the basic work of regional agriculture study. This paper constructs index system (27 indices) of regional agricultural structure types with the three big indices: natural resources, developmental level of the agro-economy, and agro-ecological conditions. This paper also endows weight to every sub-classification index by means of AHP and obtains the comprehensive evaluation value of the three types of indices with arithmetic average weight approach. The regional agricultural structure can be classified into eight types in accordance with this evaluation results. The empirical study of China shows that the 31 provinces (municipalities and autonomous regions) are of different agriculture structural types. Finally, countermeasures of sustainsable agricultural development are put forward for the different agriculture structure features. 展开更多
关键词 AGRO-ECOLOGY China Classification method Regional agriculture Structural type
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Point-governed Region Method for the Planningof Brain Surgical Path
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《Chinese Journal of Biomedical Engineering(English Edition)》 1999年第4期116-117,共2页
关键词 Figure Point-governed Region method for the Planningof Brain Surgical Path
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RESEARCH ON THE THEORY AND METHODS OF COMPREHENSIVE EVALUATION OF REGIONAL COAL RESOURCES
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《石家庄经济学院学报》 1995年第S1期99-105,共7页
consists of forecasting for the total reserves of regional mineral resources and evaluation,compreIn general,based on evaluated objects and factors involved,evaluation of mineral resources hensive evaluation of region... consists of forecasting for the total reserves of regional mineral resources and evaluation,compreIn general,based on evaluated objects and factors involved,evaluation of mineral resources hensive evaluation of regional mineral resources, and economic and technical evaluation of deposits. Here a region can be a country, a province, or a mining area, while a deposit is mainly related to a single type of mineral, although it can contain more than one types of minerals. In the past, to assess mineral resources was primarily to evaluate and forecast the total reserves of regional mineral resources. With the advancement of science, technology, and economy, the evaluation of mineral resources has developed from forecasting the reserves of them to comprehensively evaluating them on the basis of numerous factors. 展开更多
关键词 RESEARCH ON THE THEORY AND methodS OF COMPREHENSIVE EVALUATION OF REGIONAL COAL RESOURCES
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A SUPERLINEARLY CONVERGENT TRUST REGION ALGORITHM FOR LC^1 CONSTRAINED OPTIMIZATION PROBLEMS 被引量:3
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作者 欧宜贵 侯定丕 《Acta Mathematica Scientia》 SCIE CSCD 2005年第1期67-80,共14页
In this paper, a new trust region algorithm for nonlinear equality constrained LC1 optimization problems is given. It obtains a search direction at each iteration not by solving a quadratic programming subprobiem with... In this paper, a new trust region algorithm for nonlinear equality constrained LC1 optimization problems is given. It obtains a search direction at each iteration not by solving a quadratic programming subprobiem with a trust region bound, but by solving a system of linear equations. Since the computational complexity of a QP-Problem is in general much larger than that of a system of linear equations, this method proposed in this paper may reduce the computational complexity and hence improve computational efficiency. Furthermore, it is proved under appropriate assumptions that this algorithm is globally and super-linearly convergent to a solution of the original problem. Some numerical examples are reported, showing the proposed algorithm can be beneficial from a computational point of view. 展开更多
关键词 LC1 optimization ODE methods trust region methods superlinear convergence
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Trust Region Algorithm for a Class of Nonlinear Complementarity Problem 被引量:3
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作者 OU Yi-gui 《Chinese Quarterly Journal of Mathematics》 CSCD 北大核心 2007年第4期558-566,共9页
In this paper, an ODE-type trust region algorithm for solving a class of nonlinear complementarity problems is proposed. A feature of this algorithm is that only the solution of linear systems of equations is required... In this paper, an ODE-type trust region algorithm for solving a class of nonlinear complementarity problems is proposed. A feature of this algorithm is that only the solution of linear systems of equations is required at each iteration, thus avoiding the need for solving a quadratic subproblem with a trust region bound. Under some conditions, it is proven that this algorithm is globally and locally superlinear convergent. The limited numerical examples show its efficiency. 展开更多
关键词 nonlinear complementarity problems ODE methods trust region methods Fischer-Burmeister function
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An Overview of Non.Stationary Property for Massive MIMO Channel Modeling 被引量:3
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作者 ZHANG Ping CHEN Jianqiao TANG Tian 《ZTE Communications》 2017年第1期3-7,共5页
Massive multiple-input multiple-output(MIMO)emerges as one of the most promising technologies for 5G mobile communication systems.Compared to the conventional MIMO channel models,channel researches and measurements sh... Massive multiple-input multiple-output(MIMO)emerges as one of the most promising technologies for 5G mobile communication systems.Compared to the conventional MIMO channel models,channel researches and measurements show that significant nonstationary properties rise in massive MIMO channels.Therefore,an accurate channel model is indispensable for the sake of massive MIMO system design and performance evaluation.This article presents an overview of methods of modeling non-stationary properties on both the array and time axes,which are mainly divided into two major categories:birth-death(BD)process and cluster visibility region(VR)method.The main concepts and theories are described,together with useful implementation guidelines.In conclusion,a comparison between these two methods is made. 展开更多
关键词 birth-death process cluster visibility region method massive MIMO channel model non-stationary properties
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GLOBAL CONVERGENCE OF A TRUST REGION ALGORITHM USING INEXACT GRADIENT FOR EQUALITY-CONSTRAINED OPTIMIZATION 被引量:1
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作者 童小娇 周叔子 《Acta Mathematica Scientia》 SCIE CSCD 2000年第3期365-373,共9页
A trust-region algorithm is presented for a nonlinear optimization problem of equality-constraints. The characterization of the algorithm is using inexact gradient information. Global convergence results are demonstra... A trust-region algorithm is presented for a nonlinear optimization problem of equality-constraints. The characterization of the algorithm is using inexact gradient information. Global convergence results are demonstrated where the gradient values are obeyed a simple relative error condition. 展开更多
关键词 equality constraints trust region method inexact gradient global convergence
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A NEW ADAPTIVE TRUST REGION ALGORITHM FOR OPTIMIZATION PROBLEMS 被引量:1
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作者 盛洲 袁功林 崔曾如 《Acta Mathematica Scientia》 SCIE CSCD 2018年第2期479-496,共18页
It is well known that trust region methods are very effective for optimization problems. In this article, a new adaptive trust region method is presented for solving uncon- strained optimization problems. The proposed... It is well known that trust region methods are very effective for optimization problems. In this article, a new adaptive trust region method is presented for solving uncon- strained optimization problems. The proposed method combines a modified secant equation with the BFGS updated formula and an adaptive trust region radius, where the new trust region radius makes use of not only the function information but also the gradient information. Under suitable conditions, global convergence is proved, and we demonstrate the local superlinear convergence of the proposed method. The numerical results indicate that the proposed method is very efficient. 展开更多
关键词 OPTIMIZATION trust region method global convergence local convergence
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Discovery of Three Large HII Regions in the Galactic Plane 被引量:2
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作者 Wei-Bin Shi Xiao-Hui Sun +2 位作者 Jin-Lin Han Xu-Yang Gao Li Xiao 《Chinese Journal of Astronomy and Astrophysics》 CSCD 2008年第5期575-579,共5页
We discovered three large HⅡ regions: G148.8+2.3, G149.5+0.0 and G169.9+2.0 in the Sino-German A6 cm polarization survey of the Galactic plane. They have been identified based on the flat spectral indexes and the... We discovered three large HⅡ regions: G148.8+2.3, G149.5+0.0 and G169.9+2.0 in the Sino-German A6 cm polarization survey of the Galactic plane. They have been identified based on the flat spectral indexes and the strong infrared emission properties. 展开更多
关键词 radio continuum general - methods observational - HⅡ regions
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A TRUST REGION ALGORITHM VIA BILEVEL LINEAR PROGRAMMING FOR SOLVING THE GENERAL MULTICOMMODITY MINIMAL COST FLOW PROBLEMS
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作者 ZhuDetong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2004年第4期459-473,共15页
This paper proposes a nonmonotonic backtracking trust region algorithm via bilevel linear programming for solving the general multicommodity minimal cost flow problems.Using the duality theory of the linear programmin... This paper proposes a nonmonotonic backtracking trust region algorithm via bilevel linear programming for solving the general multicommodity minimal cost flow problems.Using the duality theory of the linear programming and convex theory,the generalized directional derivative of the general multicommodity minimal cost flow problems is derived.The global convergence and superlinear convergence rate of the proposed algorithm are established under some mild conditions. 展开更多
关键词 duality theory trust region method generalized directional derivative general multicommodity minimal cost flow problems.
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GPU-based discrete element simulation on flow stability of flat-bottomed hopper 被引量:1
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作者 Li Peng Zheng Zou +2 位作者 Libo Zhang Qingshan Zhu Hongzhong Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2018年第1期43-52,共10页
In this study, the flow stability of the flat-bottomed hopper was investigated via GPU-based discrete element method(DEM) simulation. With the material height inside the hopper reducing, the fluctuation of the flow ra... In this study, the flow stability of the flat-bottomed hopper was investigated via GPU-based discrete element method(DEM) simulation. With the material height inside the hopper reducing, the fluctuation of the flow rate indicates an unstable discharge. The flow regions of the unstable discharge were compared with that of the stable discharge, a key transformation zone, where the voidage showed the largest difference between unstable and stable discharge, was revealed. To identify the relevance of the key transformation zone and the hopper flow stability, the voidage variation of the key transformation zone with material height reducing was studied.A sharp increase in the voidage in the key transformation zone was considered to be the standard for judging the unstable hopper flow, and the ‘Top–Bottom effect' of the hopper was defined, which indicated the hopper flow was unstable when the hopper only had the top area and the bottom area, because the voidage of particles in the top area and the bottom area were both variables. 展开更多
关键词 Stability Discrete element method(DEM) Granular flow Top-Bottom effect Flow regions
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