Genetic Programming (GP) is an important approach to deal with complex problem analysis and modeling, and has been applied in a wide range of areas. The development of GP involves various aspects, including design of ...Genetic Programming (GP) is an important approach to deal with complex problem analysis and modeling, and has been applied in a wide range of areas. The development of GP involves various aspects, including design of genetic operators, evolutionary controls and implementations of heuristic strategy, evaluations and other mechanisms. When designing genetic operators, it is necessary to consider the possible limitations of encoding methods of individuals. And when selecting evolutionary control strategies, it is also necessary to balance search efficiency and diversity based on representation characteristics as well as the problem itself. More importantly, all of these matters, among others, have to be implemented through tedious coding work. Therefore, GP development is both complex and time-consuming. To overcome some of these difficulties that hinder the enhancement of GP development efficiency, we explore the feasibility of mutual assistance among GP variants, and then propose a rapid GP prototyping development method based on πGrammatical Evolution (πGE). It is demonstrated through regression analysis experiments that not only is this method beneficial for the GP developers to get rid of some tedious implementations, but also enables them to concentrate on the essence of the referred problem, such as individual representation, decoding means and evaluation. Additionally, it provides new insights into the roles of individual delineations in phenotypes and semantic research of individuals.展开更多
The effect of time and environment on the dimension precision and mass of LOM prototypes was experimentally investigated.It is to identify the stability of the dimension of LOM prototypes after forming.The results sho...The effect of time and environment on the dimension precision and mass of LOM prototypes was experimentally investigated.It is to identify the stability of the dimension of LOM prototypes after forming.The results show that the dimension and the mass tendency to grow,which is mainly caused by elastic recovery and moisture absorption and is characterized principally by the growth of Z dimension.Self restraint can be a significant factor to influence Z growth of LOM prototypes.展开更多
The SafeAmpCase is an innovative 3D-printed solution developed to address critical challenges in transporting and storing fragile glass drug ampoules during emergencies.This study employs a multidisciplinary approach...The SafeAmpCase is an innovative 3D-printed solution developed to address critical challenges in transporting and storing fragile glass drug ampoules during emergencies.This study employs a multidisciplinary approach—integrating biomedical engineering,advanced materials science,and emergency medicine expertise—to develop a compact,durable,and user-friendly ampoule case.A key innovation lies in the strategic selection of thermoplastic polyurethane(TPU)as the material,leveraging its superior impact resistance,flexibility,and noise-damping characteristics to ensure reliability under performance in demanding real-world conditions.To optimize the 3D printing process,key parameters,including printing temperature(220-250℃),volumetric flow rate(3-20 mm^(3)/s),retraction speed(30-90 mm/s),and retraction length(0.4-1.2 mm),were systematically adjusted using calibration models.The final optimized parameters(245℃,7 mm^(3)/s,90 mm/s,and 1.2 mm)reduced production time by 43%while preserving structural integrity.American Society for Testing and Materials(ASTM)international standard drop tests confirmed the case’s exceptional impact resistance,demonstrating a 90%reduction in ampoule breakage compared to polylactic acid plus.Further refinements,guided by feedback from 25 emergency professionals,resulted in medicationspecific color coding and an enhanced locking mechanism for usability in high-pressure situations.The final SafeAmpCase model withstood 18 consecutive drop trials without ampoule breakage,confirming its robustness in field conditions.This research underscores the transformative potential of additive manufacturing in developing customized,high-performance solutions for critical healthcare applications,setting a new benchmark for biomedical device design and rapid prototyping.展开更多
Metal device rapid prototyping with welding is one of the research interests at present. A controlled inertial droplet transfer MAG welding (CIDTMAGW) process was developed for the 3D steel device rapid prototyping wi...Metal device rapid prototyping with welding is one of the research interests at present. A controlled inertial droplet transfer MAG welding (CIDTMAGW) process was developed for the 3D steel device rapid prototyping with metal deposition. In this process, by using a special designed wire feeder, a controlled inertia is imposed on the droplet formed on the wire tip and combines with the arc force to make it detached. Thus, according to the requirements of rapid prototyping, the arc heat and the droplet detaching force can be separately controlled to attain a stable and satisfactory metal deposition process. A CIDTMAGW system and a testing manipulator for the 3D steel device rapid prototyping are presented. The required software is completed as well. The experiments proved that the geometric formation of the rapid prototyping device with welding deposition is well agreed the data of the device CAD modeling. The surface of the deposited device is comparatively smooth.展开更多
As a deposition technology, gas metal arc welding (GMAW) has shown new promise for rapid prototyping of metallic parts. During the process of metal forming using the arc of GMA W, low heat input and stable droplet t...As a deposition technology, gas metal arc welding (GMAW) has shown new promise for rapid prototyping of metallic parts. During the process of metal forming using the arc of GMA W, low heat input and stable droplet transition are critical to high quality figuration. The effects of various processing parameters on figuration quality were studied in the experiment of GMA W rapid prototyping using the wire of ERSO-6 , including welding voltage, wire feeding rate, welding speed and so on. The optimal parameters for ERSO-6 are obtained. Simultaneously, it is verified that the rapid prototyping parts with favorable structures and quality can be achieved under the conditions of low heat input and stable droplet transition.展开更多
Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction.Autografts and allografts have been used in clinical application for some time,but they have disadvantage...Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction.Autografts and allografts have been used in clinical application for some time,but they have disadvantages.With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques,the results of bone surgery may not be ideal.This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair.Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering,enhancing bone tissue regeneration in terms of mechanical strength,pore geometry,and bioactive factors,and overcoming some of the disadvantages of conventional technologies.This review focuses on the basic principles and characteristics of various fabrication technologies,such as stereolithography,selective laser sintering,and fused deposition modeling,and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering.In the near future,the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects.展开更多
During weld-bused rapid prototyping, the component experiences complex thermal process. In this paper, the temperature field evolution, thermal cycle characteristics, and temperature gradients of multi-layer multi-pus...During weld-bused rapid prototyping, the component experiences complex thermal process. In this paper, the temperature field evolution, thermal cycle characteristics, and temperature gradients of multi-layer multi-puss weld-based rapid prototyping are investigated using three-dimensional finite element models presented. The single-puss weld-bused rapid prototyping experiment is carried out. Thermal cycles calculated agree with experimental measurements. Furthermore, simulated results indicate that there exist the pre-heating effect of the fore layer and the post-heating effect of the rear layer in the multi-layer multi-pass weld-based rapid prototyping. In the first layer, the heat accumulates obviously. After the first layer, the dimension increase of the high temperature region behind the molten pool is not obvious. The heat diffusion condition in the first layer is the best, the heat diffusion condition in the second layer is the worst, and the heat diffusion conditions in the higher layers improve gradually.展开更多
In order to realize the closed-loop control for rapid prototyping process based on gas metal arc welding, the geometric parameters of weld beads should be detected. In this study, a vision sensor system consisting of ...In order to realize the closed-loop control for rapid prototyping process based on gas metal arc welding, the geometric parameters of weld beads should be detected. In this study, a vision sensor system consisting of a linear laser projector and a CCD camera was designed to collect images of weld beads. Then, an image processing approach which combines with a Gaassian filter and an improved gravity method was used to extract the centerline of a light stripe based on VC ++. Feature points of the centerline were identical directly by means of an image fusion algorithm. Experimental results show that image fusion is an effective approach to measure the width and height of the weld bead with high accuracy. This method can identify beads effectively in multi-pass welding and avoid designing different modes to suit all kinds of shapes.展开更多
As a deposition technology, robotic metal active gas (MAG) welding has shown new promise for rapid prototyping ( RP) of metallic parts. During the process of metal forming using robotic MAG welding, sectional prof...As a deposition technology, robotic metal active gas (MAG) welding has shown new promise for rapid prototyping ( RP) of metallic parts. During the process of metal forming using robotic MAG welding, sectional profile of single-puss welded bead is critical to formed accuracy and quality of metal pans. In this paper, the experiments of single-pass welded bead for rapid prototyping using robotic MAG welding were carried out. The effect of some edge detectors on the cross-sectional edge of welded bead was discussed and curve fitting was applied using least square fitting. Consequently, the mathematical model of welded bead profile was developed. The experimental results show that good shape could be obtained under suitable welding parameters. Canny operator is suitable to edge detection of welded bead profile, and the mathematical model of welded bead profile developed is approximately parabola.展开更多
This article first generalizes the basic engineering phases of modern rapid prototyping processes, and then describes the techniques of data capture for data modeling and model making. The article also provides a brie...This article first generalizes the basic engineering phases of modern rapid prototyping processes, and then describes the techniques of data capture for data modeling and model making. The article also provides a brief overview of the photogrametric techniques of restitution of 3D objects, and highlights the difficulties and limitations of existing methods. It therefore presents a novel approach to photo-modeling for acquiring 3D model data from single 2D photorealistic images. Implementation of the approach is then described against a effectiveness of photo-modeling practice. background of rapid prototyping processes to demonstrate the展开更多
Colloidal gels made of oppositely charged nanoparticles are a novel class of hydrogels and can exhibit pseudoplastic behavior which will enable them to mold easily into specific shapes.These moldable gels can be used ...Colloidal gels made of oppositely charged nanoparticles are a novel class of hydrogels and can exhibit pseudoplastic behavior which will enable them to mold easily into specific shapes.These moldable gels can be used as building blocks to self-assemble into integral scaffolds from bottom to up through electrostatic forces.However,they are too weak to maintain scaffold morphology just depending on interparticle interactions such as Van der Waals attraction and electrostatic forces especially for bone tissue engineering.In this study,oppositely charged gelatin nanoparticles were firstly prepared by two-step desolvation method,followed by the mixture with water to form colloid gels.To solve the problem of weak mechanical performance of colloid gels, gelatin macromolecules were introduced into the prepared gels to form blend gels.The blend gels can be easily processed into three-dimensional( 3D) porous scaffolds via motor assisted microsyringe( MAM)system,a nozzle-based rapid prototyping technology,under mild conditions.After fabrication the scaffolds were crosslinked by glutaraldehyde( GA,25% solution in water by weight),then the crosslinked gelatin macromolecules network could form to improve the mechanical properties of colloid gels.The average particle size and zeta potential of gelatin nanoparticles were measured by NanoZS instrument.The morphology and microstructures of scaffolds were characterized by macroscopic images.The mechanical properties of the scaffolds were studied by a universal material testing machine.展开更多
A gearbox in-the-loop control platform using dSPACE real-time system is designed for the study on the control technology of pneumatic selecting and shifting actuators based on rapid control prototyping.The operational...A gearbox in-the-loop control platform using dSPACE real-time system is designed for the study on the control technology of pneumatic selecting and shifting actuators based on rapid control prototyping.The operational principle of such actuators was analyzed using dSPACE hardware and software,resulting in a better knowledge of the logical relationship among solenoid valves,gear positions of cylinders and system input/output.Based on these,a control model was developed under the Matlab/Simulink environment and rapidly improved to meet requirements through experiments.Relevant tests have shown that analysis efficiency on selecting and shifting actuators could be raised and development of control strategy facilitated.展开更多
To aim at prototype parts fabricated with fused deposition modeling (FDM) process, the problems how to improve and enhance their surface micro-precision are studied. The producing mechanism of surface roughness is e...To aim at prototype parts fabricated with fused deposition modeling (FDM) process, the problems how to improve and enhance their surface micro-precision are studied. The producing mechanism of surface roughness is explained with three aspects concretely including the principle error of rapid prototyping (RP) process, the inherent characteristics of FDM process, and some mi- cro-scratches on the surface of the extruded fiber. Based on the micro-characters of section shape of the FDM prototype, a physical model reflecting the outer shape characters is abstracted. With the physical simplified and deduced, the evaluating equations of surface roughness are acquired. According to the FDM sample parts with special design for experimental measurement, the real surface roughness values of different inclined planes are obtained. And the measuring values of surface roughness are compared with the calculation values. Furthermore, the causes of surface roughness deviation between measuring values and calculation values are respectively analyzed and studied. With the references of analytic conclusions, the measuring values of the experimental part surface are revised, and the revised values nearly accord with the calculation values. Based on the influencing principles of FDM process parameters and special post processing of FDM prototype parts, some concrete measures are proposed to reduce the surface roughness of FDM parts, and the applying effects are better.展开更多
A kind of 3D color graphics display system for the STL model is developed by calling the functions from Open GL graphic library through VC++6.0 under the Windows environment in this paper. The STL model is a high qual...A kind of 3D color graphics display system for the STL model is developed by calling the functions from Open GL graphic library through VC++6.0 under the Windows environment in this paper. The STL model is a high quality one that can be quiescent or animated. This system is conducive to find out the disfigurement of the STL model in a rapid prototyping process and to repair it. Therefore, the component quality can be enhanced.展开更多
Traditional soft lithography based PDMS device fabrication requires complex procedures carried out in a clean room. Herein, we report a photolithography-free method that rapidly produces PDMS devices in 30 min. By usi...Traditional soft lithography based PDMS device fabrication requires complex procedures carried out in a clean room. Herein, we report a photolithography-free method that rapidly produces PDMS devices in 30 min. By using a laser cutter to ablate a tape, a male photoresist mold can be obtained within 5 min by a simple heating-step, which offers significant superiority over currently used photolithographybased method. Since it requires minimal energy to cut the tape, our fabrication strategy shows good resolution(~ 100 μm) and high throughput. Furthermore, the micro-mold height can be easily controlled by changing the tape types and layers. As a proof-of-concept, we demonstrated that the fabricated PDMS devices are compatible with biochemical reactions such as quenching reaction of KI to fluorescein and cell culture/staining. Collectively, our strategy shows advantages of low input, simple operation procedure and short fabrication time, therefore we believe this photolithography-free method could serve as a promising way for rapid prototyping of PDMS devices and be widely used in general biochemical laboratories.展开更多
At present, the most common micro/nano-scale fabri ca tion processes include the plane silicon process based on IC technology, stereo silicon process, LIGA, quasi-LIGA based on near ultra violet deep lithography, MEMS...At present, the most common micro/nano-scale fabri ca tion processes include the plane silicon process based on IC technology, stereo silicon process, LIGA, quasi-LIGA based on near ultra violet deep lithography, MEMS, energy beam etching and micro/nano-machining, etc. A common problem for t hese processes is the difficulty to fabricate arbitrary form for 3-dimensional micro/nano-parts, devices or mechanisms. To develop advanced MEMS manufacturin g technology, and to achieve fabrication of true 3-dimensional parts, devices or mechanisms, this paper proposes a nanofabrication technology for rapid proto typing of 3-dimensional parts, using plasma chemical vapor deposition (PCVD). This process can be describes as follows: A laser beam is produced by a low power, quasi molecule laser. It enters the vac uum chamber through a window, and is focused on with the substrate surface. A ga s in the chamber is ionized by the laser beam to produce PCVD on the substrate s urface, and forms a particle of the size of Ф100 nm (its thickness is about 100 nm). When the laser beam moves along X-axis, many particles form a line. Then the laser beam moves one step in Y-axis to form a new line. A plane is complete d by many lines. Then the substrate moves in Z-axis to form new plane. Eventu ally, many planes form a 3-dimensional component. Using available CAD/CAM softw are with this process, rapid prototyping of complex components can be achieved. A nanometer precision linear motor, such as that described in Chinese national p atent (patent No. ZL 98 2 16753.9), can be used to obtain the nanometer precisio n movements in the process. The process does not require mask, can be used for v arious rapid prototyping materials, to obtain high fabrication precision (its sc ale precision is 15 nm), and larger ratio of height to width of micro/nano-stru cture. It can find widespread applications in the fabrication of micro-mechani sm, trimming IC, and fabricating minilens, etc.展开更多
This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP...This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP of scheme design prototype was first built,where thermal,structural,and multidisciplinary knowledge could be integrated for visualization.To implement visualized computing,the membership function of fuzzy decision-making was optimized using a genetic algorithm.Transient thermodynamic,structural statics,and flow field analyses were conducted,especially for glass fiber composite materials,which have the characteristics of high strength,corrosion resistance,temperature resistance,dimensional stability,and electrical insulation.An electrothermal experiment was performed by measuring the temperature and changes in temperature during RP.Infrared thermographs were obtained using thermal field measurements to determine the temperature distribution.A numerical analysis of a lightweight ribbed ergonomic artifact is presented to illustrate the VCDT.Moreover,manufacturability was verified based on a thermal-solid coupled finite element analysis.The physical experiment and practice proved that the proposed VCDT provided a robust design paradigm for a layered RP between the steady balance of electrothermal regulation and manufacturing efficacy under hybrid uncertainties.展开更多
Rapid prototype manufacturing(RPM) is a new advanced manufacturing technology, which is based on the philosophy of materials increasing of lay by lay forming. Zero adventure rapid design/manufacturing can be realized ...Rapid prototype manufacturing(RPM) is a new advanced manufacturing technology, which is based on the philosophy of materials increasing of lay by lay forming. Zero adventure rapid design/manufacturing can be realized with rapid prototypes of 3D CAD of products. Rapid prototyping has been an effective tool of R&D of new products. A novel rapid prototyping and manufacturing (RP&M) technique is brought forward. The principle of the process is to form layered sections and to make the prototype or part layer by layer by deflection projection of electric charged powder granules passing through electric or magnetic field and by controllable line and field scan of the powder granule beam. The feasibility issue of the process is theoretically and experimentally investigated.It shows that deflection projection of electric charged powder granules beam passing through electric field can be significant and feasible to the rapid prototyping technique.展开更多
The traditional software development model commonly named “waterfall” is unable to cope with the increasing functionality and complexity of modern embedded systems. In addition, it is unable to support the ability f...The traditional software development model commonly named “waterfall” is unable to cope with the increasing functionality and complexity of modern embedded systems. In addition, it is unable to support the ability for businesses to quickly respond to new market opportunities due to changing requirements. As a response, the software development community developed the Agile Methodologies (e.g., extreme Programming, Scrum) which were also adopted by the Embedded System community. However, failures and bad experiences in applying Agile Methodologies to the development of embedded systems have not been reported in the literature. Therefore, this paper contributes a detailed account of our first-time experiences adopting an agile approach in the prototype development of a wireless environment data acquisition system in an academic environment. We successfully applied a subset of the extreme Programming (XP) methodology to our software development using the Python programming language, an experience that demonstrated its benefits in shaping the design of the software and also increasing productivity. We used an incremental development approach for the hardware components and adopted a “cumulative testing” approach. For the overall development process management, however, we concluded that the Promise/Commitment-Based Project Management (PB-PM/CBPM) was better suited. We discovered that software and hardware components of embedded systems are best developed in parallel or near-parallel. We learned that software components that pass automated tests may not survive in the tests against the hardware. Throughout this rapid prototyping effort, factors like team size and our availability as graduate students were major obstacles to fully apply the XP methodology.展开更多
The rapid prototyping biomodels manufacturing is a recent technology with great importance in oral and maxillofacial surgery. It provides a better surgical planning, decrease of anesthesia time and great functional an...The rapid prototyping biomodels manufacturing is a recent technology with great importance in oral and maxillofacial surgery. It provides a better surgical planning, decrease of anesthesia time and great functional and esthetic results. The aim of this experimental study was to evaluate the accuracy of rapid prototyping biomodels built by three-dimensional printing (3DP) technique, since this is one of the least expensive methods available. Linear measurements of standardized bone defects and anatomic distances were compared using a digital caliper of high precision in nine dry mandibles (gold standard) and their respective biomodels. The Bland-Altman test was used for statistical analysis (5% level of significance). The results showed strong concordance between the dry mandibles and their respective biomodels, with discrepancies smaller than 2 mmin most cases (97.4%). We can conclude that the biomodels built by 3DP technique can be used for surgical planning in Dentistry.展开更多
文摘Genetic Programming (GP) is an important approach to deal with complex problem analysis and modeling, and has been applied in a wide range of areas. The development of GP involves various aspects, including design of genetic operators, evolutionary controls and implementations of heuristic strategy, evaluations and other mechanisms. When designing genetic operators, it is necessary to consider the possible limitations of encoding methods of individuals. And when selecting evolutionary control strategies, it is also necessary to balance search efficiency and diversity based on representation characteristics as well as the problem itself. More importantly, all of these matters, among others, have to be implemented through tedious coding work. Therefore, GP development is both complex and time-consuming. To overcome some of these difficulties that hinder the enhancement of GP development efficiency, we explore the feasibility of mutual assistance among GP variants, and then propose a rapid GP prototyping development method based on πGrammatical Evolution (πGE). It is demonstrated through regression analysis experiments that not only is this method beneficial for the GP developers to get rid of some tedious implementations, but also enables them to concentrate on the essence of the referred problem, such as individual representation, decoding means and evaluation. Additionally, it provides new insights into the roles of individual delineations in phenotypes and semantic research of individuals.
文摘The effect of time and environment on the dimension precision and mass of LOM prototypes was experimentally investigated.It is to identify the stability of the dimension of LOM prototypes after forming.The results show that the dimension and the mass tendency to grow,which is mainly caused by elastic recovery and moisture absorption and is characterized principally by the growth of Z dimension.Self restraint can be a significant factor to influence Z growth of LOM prototypes.
基金Open access funding provided by Ben-Gurion University.
文摘The SafeAmpCase is an innovative 3D-printed solution developed to address critical challenges in transporting and storing fragile glass drug ampoules during emergencies.This study employs a multidisciplinary approach—integrating biomedical engineering,advanced materials science,and emergency medicine expertise—to develop a compact,durable,and user-friendly ampoule case.A key innovation lies in the strategic selection of thermoplastic polyurethane(TPU)as the material,leveraging its superior impact resistance,flexibility,and noise-damping characteristics to ensure reliability under performance in demanding real-world conditions.To optimize the 3D printing process,key parameters,including printing temperature(220-250℃),volumetric flow rate(3-20 mm^(3)/s),retraction speed(30-90 mm/s),and retraction length(0.4-1.2 mm),were systematically adjusted using calibration models.The final optimized parameters(245℃,7 mm^(3)/s,90 mm/s,and 1.2 mm)reduced production time by 43%while preserving structural integrity.American Society for Testing and Materials(ASTM)international standard drop tests confirmed the case’s exceptional impact resistance,demonstrating a 90%reduction in ampoule breakage compared to polylactic acid plus.Further refinements,guided by feedback from 25 emergency professionals,resulted in medicationspecific color coding and an enhanced locking mechanism for usability in high-pressure situations.The final SafeAmpCase model withstood 18 consecutive drop trials without ampoule breakage,confirming its robustness in field conditions.This research underscores the transformative potential of additive manufacturing in developing customized,high-performance solutions for critical healthcare applications,setting a new benchmark for biomedical device design and rapid prototyping.
文摘Metal device rapid prototyping with welding is one of the research interests at present. A controlled inertial droplet transfer MAG welding (CIDTMAGW) process was developed for the 3D steel device rapid prototyping with metal deposition. In this process, by using a special designed wire feeder, a controlled inertia is imposed on the droplet formed on the wire tip and combines with the arc force to make it detached. Thus, according to the requirements of rapid prototyping, the arc heat and the droplet detaching force can be separately controlled to attain a stable and satisfactory metal deposition process. A CIDTMAGW system and a testing manipulator for the 3D steel device rapid prototyping are presented. The required software is completed as well. The experiments proved that the geometric formation of the rapid prototyping device with welding deposition is well agreed the data of the device CAD modeling. The surface of the deposited device is comparatively smooth.
文摘As a deposition technology, gas metal arc welding (GMAW) has shown new promise for rapid prototyping of metallic parts. During the process of metal forming using the arc of GMA W, low heat input and stable droplet transition are critical to high quality figuration. The effects of various processing parameters on figuration quality were studied in the experiment of GMA W rapid prototyping using the wire of ERSO-6 , including welding voltage, wire feeding rate, welding speed and so on. The optimal parameters for ERSO-6 are obtained. Simultaneously, it is verified that the rapid prototyping parts with favorable structures and quality can be achieved under the conditions of low heat input and stable droplet transition.
基金supported by the Science and Technology Commission of Shanghai Municipality(No.15JC1491003),China
文摘Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction.Autografts and allografts have been used in clinical application for some time,but they have disadvantages.With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques,the results of bone surgery may not be ideal.This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair.Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering,enhancing bone tissue regeneration in terms of mechanical strength,pore geometry,and bioactive factors,and overcoming some of the disadvantages of conventional technologies.This review focuses on the basic principles and characteristics of various fabrication technologies,such as stereolithography,selective laser sintering,and fused deposition modeling,and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering.In the near future,the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects.
基金This research work is supported by the National Natural Science Foundation of China under Grant No. 51175119.
文摘During weld-bused rapid prototyping, the component experiences complex thermal process. In this paper, the temperature field evolution, thermal cycle characteristics, and temperature gradients of multi-layer multi-puss weld-based rapid prototyping are investigated using three-dimensional finite element models presented. The single-puss weld-bused rapid prototyping experiment is carried out. Thermal cycles calculated agree with experimental measurements. Furthermore, simulated results indicate that there exist the pre-heating effect of the fore layer and the post-heating effect of the rear layer in the multi-layer multi-pass weld-based rapid prototyping. In the first layer, the heat accumulates obviously. After the first layer, the dimension increase of the high temperature region behind the molten pool is not obvious. The heat diffusion condition in the first layer is the best, the heat diffusion condition in the second layer is the worst, and the heat diffusion conditions in the higher layers improve gradually.
基金This research work is supported by the National Natural Science Foundation of China under Grant No. 51175119.
文摘In order to realize the closed-loop control for rapid prototyping process based on gas metal arc welding, the geometric parameters of weld beads should be detected. In this study, a vision sensor system consisting of a linear laser projector and a CCD camera was designed to collect images of weld beads. Then, an image processing approach which combines with a Gaassian filter and an improved gravity method was used to extract the centerline of a light stripe based on VC ++. Feature points of the centerline were identical directly by means of an image fusion algorithm. Experimental results show that image fusion is an effective approach to measure the width and height of the weld bead with high accuracy. This method can identify beads effectively in multi-pass welding and avoid designing different modes to suit all kinds of shapes.
文摘As a deposition technology, robotic metal active gas (MAG) welding has shown new promise for rapid prototyping ( RP) of metallic parts. During the process of metal forming using robotic MAG welding, sectional profile of single-puss welded bead is critical to formed accuracy and quality of metal pans. In this paper, the experiments of single-pass welded bead for rapid prototyping using robotic MAG welding were carried out. The effect of some edge detectors on the cross-sectional edge of welded bead was discussed and curve fitting was applied using least square fitting. Consequently, the mathematical model of welded bead profile was developed. The experimental results show that good shape could be obtained under suitable welding parameters. Canny operator is suitable to edge detection of welded bead profile, and the mathematical model of welded bead profile developed is approximately parabola.
基金This work is supported by Cheung Kong Scholars Program of the People's Republic of China, in association with Southeast University, Nanjing, PRC. (No.seuzx042001)
文摘This article first generalizes the basic engineering phases of modern rapid prototyping processes, and then describes the techniques of data capture for data modeling and model making. The article also provides a brief overview of the photogrametric techniques of restitution of 3D objects, and highlights the difficulties and limitations of existing methods. It therefore presents a novel approach to photo-modeling for acquiring 3D model data from single 2D photorealistic images. Implementation of the approach is then described against a effectiveness of photo-modeling practice. background of rapid prototyping processes to demonstrate the
基金National Natural Science Foundations of China(Nos.30973105,31271035)Science and Technology Commission of Shanghai Municipality,China(No.11nm0506200)Ph.D.Programs Foundation of Ministry of Education of China(No.20130075110005)
文摘Colloidal gels made of oppositely charged nanoparticles are a novel class of hydrogels and can exhibit pseudoplastic behavior which will enable them to mold easily into specific shapes.These moldable gels can be used as building blocks to self-assemble into integral scaffolds from bottom to up through electrostatic forces.However,they are too weak to maintain scaffold morphology just depending on interparticle interactions such as Van der Waals attraction and electrostatic forces especially for bone tissue engineering.In this study,oppositely charged gelatin nanoparticles were firstly prepared by two-step desolvation method,followed by the mixture with water to form colloid gels.To solve the problem of weak mechanical performance of colloid gels, gelatin macromolecules were introduced into the prepared gels to form blend gels.The blend gels can be easily processed into three-dimensional( 3D) porous scaffolds via motor assisted microsyringe( MAM)system,a nozzle-based rapid prototyping technology,under mild conditions.After fabrication the scaffolds were crosslinked by glutaraldehyde( GA,25% solution in water by weight),then the crosslinked gelatin macromolecules network could form to improve the mechanical properties of colloid gels.The average particle size and zeta potential of gelatin nanoparticles were measured by NanoZS instrument.The morphology and microstructures of scaffolds were characterized by macroscopic images.The mechanical properties of the scaffolds were studied by a universal material testing machine.
文摘A gearbox in-the-loop control platform using dSPACE real-time system is designed for the study on the control technology of pneumatic selecting and shifting actuators based on rapid control prototyping.The operational principle of such actuators was analyzed using dSPACE hardware and software,resulting in a better knowledge of the logical relationship among solenoid valves,gear positions of cylinders and system input/output.Based on these,a control model was developed under the Matlab/Simulink environment and rapidly improved to meet requirements through experiments.Relevant tests have shown that analysis efficiency on selecting and shifting actuators could be raised and development of control strategy facilitated.
基金This project is supported by National Natural Science Foundation of China (No. 50575139)
文摘To aim at prototype parts fabricated with fused deposition modeling (FDM) process, the problems how to improve and enhance their surface micro-precision are studied. The producing mechanism of surface roughness is explained with three aspects concretely including the principle error of rapid prototyping (RP) process, the inherent characteristics of FDM process, and some mi- cro-scratches on the surface of the extruded fiber. Based on the micro-characters of section shape of the FDM prototype, a physical model reflecting the outer shape characters is abstracted. With the physical simplified and deduced, the evaluating equations of surface roughness are acquired. According to the FDM sample parts with special design for experimental measurement, the real surface roughness values of different inclined planes are obtained. And the measuring values of surface roughness are compared with the calculation values. Furthermore, the causes of surface roughness deviation between measuring values and calculation values are respectively analyzed and studied. With the references of analytic conclusions, the measuring values of the experimental part surface are revised, and the revised values nearly accord with the calculation values. Based on the influencing principles of FDM process parameters and special post processing of FDM prototype parts, some concrete measures are proposed to reduce the surface roughness of FDM parts, and the applying effects are better.
文摘A kind of 3D color graphics display system for the STL model is developed by calling the functions from Open GL graphic library through VC++6.0 under the Windows environment in this paper. The STL model is a high quality one that can be quiescent or animated. This system is conducive to find out the disfigurement of the STL model in a rapid prototyping process and to repair it. Therefore, the component quality can be enhanced.
基金financial support from the National Natural Science Foundation of China (Nos.21904139,22074152,21735007)Chinese Academy of Sciences (Nos.Y9Y1041001,YJKYYQ20170026)。
文摘Traditional soft lithography based PDMS device fabrication requires complex procedures carried out in a clean room. Herein, we report a photolithography-free method that rapidly produces PDMS devices in 30 min. By using a laser cutter to ablate a tape, a male photoresist mold can be obtained within 5 min by a simple heating-step, which offers significant superiority over currently used photolithographybased method. Since it requires minimal energy to cut the tape, our fabrication strategy shows good resolution(~ 100 μm) and high throughput. Furthermore, the micro-mold height can be easily controlled by changing the tape types and layers. As a proof-of-concept, we demonstrated that the fabricated PDMS devices are compatible with biochemical reactions such as quenching reaction of KI to fluorescein and cell culture/staining. Collectively, our strategy shows advantages of low input, simple operation procedure and short fabrication time, therefore we believe this photolithography-free method could serve as a promising way for rapid prototyping of PDMS devices and be widely used in general biochemical laboratories.
文摘At present, the most common micro/nano-scale fabri ca tion processes include the plane silicon process based on IC technology, stereo silicon process, LIGA, quasi-LIGA based on near ultra violet deep lithography, MEMS, energy beam etching and micro/nano-machining, etc. A common problem for t hese processes is the difficulty to fabricate arbitrary form for 3-dimensional micro/nano-parts, devices or mechanisms. To develop advanced MEMS manufacturin g technology, and to achieve fabrication of true 3-dimensional parts, devices or mechanisms, this paper proposes a nanofabrication technology for rapid proto typing of 3-dimensional parts, using plasma chemical vapor deposition (PCVD). This process can be describes as follows: A laser beam is produced by a low power, quasi molecule laser. It enters the vac uum chamber through a window, and is focused on with the substrate surface. A ga s in the chamber is ionized by the laser beam to produce PCVD on the substrate s urface, and forms a particle of the size of Ф100 nm (its thickness is about 100 nm). When the laser beam moves along X-axis, many particles form a line. Then the laser beam moves one step in Y-axis to form a new line. A plane is complete d by many lines. Then the substrate moves in Z-axis to form new plane. Eventu ally, many planes form a 3-dimensional component. Using available CAD/CAM softw are with this process, rapid prototyping of complex components can be achieved. A nanometer precision linear motor, such as that described in Chinese national p atent (patent No. ZL 98 2 16753.9), can be used to obtain the nanometer precisio n movements in the process. The process does not require mask, can be used for v arious rapid prototyping materials, to obtain high fabrication precision (its sc ale precision is 15 nm), and larger ratio of height to width of micro/nano-stru cture. It can find widespread applications in the fabrication of micro-mechani sm, trimming IC, and fabricating minilens, etc.
基金the National Natural Science Foundation of China,Nos.51935009 and 51821093National key research and development project of China,No.2022YFB3303303+2 种基金Zhejiang University president special fund financed by Zhejiang province,No.2021XZZX008Zhejiang provincial key research and development project of China,Nos.2023C01060,LZY22E060002 and LZ22E050008The Ng Teng Fong Charitable Foundation in the form of ZJU-SUTD IDEA Grant,No.188170-11102.
文摘This study presents a robustness optimization method for rapid prototyping(RP)of functional artifacts based on visualized computing digital twins(VCDT).A generalized multiobjective robustness optimization model for RP of scheme design prototype was first built,where thermal,structural,and multidisciplinary knowledge could be integrated for visualization.To implement visualized computing,the membership function of fuzzy decision-making was optimized using a genetic algorithm.Transient thermodynamic,structural statics,and flow field analyses were conducted,especially for glass fiber composite materials,which have the characteristics of high strength,corrosion resistance,temperature resistance,dimensional stability,and electrical insulation.An electrothermal experiment was performed by measuring the temperature and changes in temperature during RP.Infrared thermographs were obtained using thermal field measurements to determine the temperature distribution.A numerical analysis of a lightweight ribbed ergonomic artifact is presented to illustrate the VCDT.Moreover,manufacturability was verified based on a thermal-solid coupled finite element analysis.The physical experiment and practice proved that the proposed VCDT provided a robust design paradigm for a layered RP between the steady balance of electrothermal regulation and manufacturing efficacy under hybrid uncertainties.
文摘Rapid prototype manufacturing(RPM) is a new advanced manufacturing technology, which is based on the philosophy of materials increasing of lay by lay forming. Zero adventure rapid design/manufacturing can be realized with rapid prototypes of 3D CAD of products. Rapid prototyping has been an effective tool of R&D of new products. A novel rapid prototyping and manufacturing (RP&M) technique is brought forward. The principle of the process is to form layered sections and to make the prototype or part layer by layer by deflection projection of electric charged powder granules passing through electric or magnetic field and by controllable line and field scan of the powder granule beam. The feasibility issue of the process is theoretically and experimentally investigated.It shows that deflection projection of electric charged powder granules beam passing through electric field can be significant and feasible to the rapid prototyping technique.
文摘The traditional software development model commonly named “waterfall” is unable to cope with the increasing functionality and complexity of modern embedded systems. In addition, it is unable to support the ability for businesses to quickly respond to new market opportunities due to changing requirements. As a response, the software development community developed the Agile Methodologies (e.g., extreme Programming, Scrum) which were also adopted by the Embedded System community. However, failures and bad experiences in applying Agile Methodologies to the development of embedded systems have not been reported in the literature. Therefore, this paper contributes a detailed account of our first-time experiences adopting an agile approach in the prototype development of a wireless environment data acquisition system in an academic environment. We successfully applied a subset of the extreme Programming (XP) methodology to our software development using the Python programming language, an experience that demonstrated its benefits in shaping the design of the software and also increasing productivity. We used an incremental development approach for the hardware components and adopted a “cumulative testing” approach. For the overall development process management, however, we concluded that the Promise/Commitment-Based Project Management (PB-PM/CBPM) was better suited. We discovered that software and hardware components of embedded systems are best developed in parallel or near-parallel. We learned that software components that pass automated tests may not survive in the tests against the hardware. Throughout this rapid prototyping effort, factors like team size and our availability as graduate students were major obstacles to fully apply the XP methodology.
基金FAPESB(Salvador,Bahia,Brazil)by the financial support.
文摘The rapid prototyping biomodels manufacturing is a recent technology with great importance in oral and maxillofacial surgery. It provides a better surgical planning, decrease of anesthesia time and great functional and esthetic results. The aim of this experimental study was to evaluate the accuracy of rapid prototyping biomodels built by three-dimensional printing (3DP) technique, since this is one of the least expensive methods available. Linear measurements of standardized bone defects and anatomic distances were compared using a digital caliper of high precision in nine dry mandibles (gold standard) and their respective biomodels. The Bland-Altman test was used for statistical analysis (5% level of significance). The results showed strong concordance between the dry mandibles and their respective biomodels, with discrepancies smaller than 2 mmin most cases (97.4%). We can conclude that the biomodels built by 3DP technique can be used for surgical planning in Dentistry.