Current minimization programs do not permit full control over different aspects of minimization algorithm such as distance or probability measures and may not allow for unequal allocation ratios. This article describe...Current minimization programs do not permit full control over different aspects of minimization algorithm such as distance or probability measures and may not allow for unequal allocation ratios. This article describes the implementation of “MinimPy” an open-source minimization program in Python programming language, which provides full customizetion of minimization features. MinimPy supports naive and biased coin minimization together with various new and classic distance measures. Data syncing is provided to facilitate minimization of multicenter trial over the network. MinimPy can easily be modified to fit special needs of clinical trials and in particular change it to a pure web application, though it currently supports network syncing of data in multi-center trials using network repositories.展开更多
Ⅰ. INTRODUCTIONMonte Carlo renormalization group method (MCRG) has become a powerful technical tool for the study of critical behaviour and continuum limit of discrete systems since 1976. The method is therefore wide...Ⅰ. INTRODUCTIONMonte Carlo renormalization group method (MCRG) has become a powerful technical tool for the study of critical behaviour and continuum limit of discrete systems since 1976. The method is therefore widely applied to the study of fixed point and critical exponents in statistical models, and to the study of phase transitions, β function and scaling behaviour for some gauge fields in lattice gauge theories.展开更多
文摘Current minimization programs do not permit full control over different aspects of minimization algorithm such as distance or probability measures and may not allow for unequal allocation ratios. This article describes the implementation of “MinimPy” an open-source minimization program in Python programming language, which provides full customizetion of minimization features. MinimPy supports naive and biased coin minimization together with various new and classic distance measures. Data syncing is provided to facilitate minimization of multicenter trial over the network. MinimPy can easily be modified to fit special needs of clinical trials and in particular change it to a pure web application, though it currently supports network syncing of data in multi-center trials using network repositories.
基金Project supported by the National Natural Science Foundation of China
文摘Ⅰ. INTRODUCTIONMonte Carlo renormalization group method (MCRG) has become a powerful technical tool for the study of critical behaviour and continuum limit of discrete systems since 1976. The method is therefore widely applied to the study of fixed point and critical exponents in statistical models, and to the study of phase transitions, β function and scaling behaviour for some gauge fields in lattice gauge theories.