期刊文献+
共找到1,595篇文章
< 1 2 80 >
每页显示 20 50 100
Output Type Guided Random Test Case Generation for String Validation Routines
1
作者 Chenhui Cui Rubing Huang +1 位作者 Jinfu Chen Yunan Zhou 《Tsinghua Science and Technology》 2025年第6期2467-2486,共20页
String validation routines have been widely used in many real-world applications,such as email validation and postcode validation.String test cases are adopted to test these validation routines,to identify potential d... String validation routines have been widely used in many real-world applications,such as email validation and postcode validation.String test cases are adopted to test these validation routines,to identify potential defects and security risks.Random Testing(RT)is a well-known testing approach to randomly generate string test cases from the input domain(i.e.,the set of all possible test inputs),which is simple to implement at a low cost.However,its testing effectiveness may be unsatisfactory for string validation routines.The main reason for this is that RT may have a high probability to generate invalid rather than valid string test cases,due to its randomness property.This research proposes a new RT approach based on the output types(i.e.,valid and invalid strings)for string validation routines,namely Output-type-guided Random Testing(RTO),which attempts to randomly generate both valid and invalid string test cases with a certain probability.This research performed an empirical study involving several real-world string validation routines collected from ten Java open-source projects,to investigate and compare testing performances of RT-O against the previous two widely-used RT methods.The results show that the generated string test cases by RT-O outperform test cases generated by other RT methods. 展开更多
关键词 software testing random testing(RT) string validation routines string test cases test case generation
原文传递
Control method for multi-input multi-output non-Gaussian random vibration test with cross spectra consideration 被引量:12
2
作者 Ronghui ZHENG Huaihai CHEN Xudong HE 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2017年第6期1895-1906,共12页
A control method for Multi-Input Multi-Output(MIMO) non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified ... A control method for Multi-Input Multi-Output(MIMO) non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified references composed of auto spectral densities, cross spectral densities and kurtoses on the test article in the laboratory. It is found that the cross spectral densities will bring intractable coupling problems and induce difficulty for the control of the multioutput kurtoses. Hence, a sequential phase modification method is put forward to solve the coupling problems in multi-input multi-output non-Gaussian random vibration test. To achieve the specified responses, an improved zero memory nonlinear transformation is utilized first to modify the Fourier phases of the signals with sequential phase modification method to obtain one frame reference response signals which satisfy the reference spectra and reference kurtoses. Then, an inverse system method is used in frequency domain to obtain the continuous stationary drive signals. At the same time, the matrix power control algorithm is utilized to control the spectra and kurtoses of the response signals further. At the end of the paper, a simulation example with a cantilever beam and a vibration shaker test are implemented and the results support the proposed method very well. 展开更多
关键词 Cross spectra Kurtosis control Multi-input multi-output NON-GAUSSIAN random vibration test
原文传递
Matrix Power Control Algorithm for Multi-input Multi-output Random Vibration Test 被引量:13
3
作者 CUI Xuli CHEN Huaihai HE Xudong JIANG Shuangyan 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2011年第6期741-748,共8页
Both auto-power spectrum and cross-power spectrum need to be controlled in multi-input multi-output (MIMO) random vibration test. During the control process with the difference control algorithm (DCA), a lower tri... Both auto-power spectrum and cross-power spectrum need to be controlled in multi-input multi-output (MIMO) random vibration test. During the control process with the difference control algorithm (DCA), a lower triangular matrix is derived from Cholesky decomposition of a reference spectrum matrix. The diagonal elements of the lower triangular matrix (DELTM) may become negative. These negative values have no meaning in physical significance and can cause divergence of auto-power spectrum control. A proportional root mean square control algorithm (PRMSCA) provides another method to avoid the divergence caused by negative values of DELTM, but PRMSCA cannot control the cross-power spectrum. A new control algorithm named matrix power control algorithm (MPCA) is proposed in the paper. MPCA can guarantee that DELTM is always positive in the auto-power spectrum control. MPCA can also control the cross-power spectrum. After these three control algorithms are analyzed, three-input three-output random vibration control tests are implemented on a three-axis vibration shaker. The results show the validity of the proposed MPCA. 展开更多
关键词 multi-input multi-output environmental testing vibration control random vibration auto-power spectrum cross-power spectrum
原文传递
Random testing for system-level functional verification of system-on-chip 被引量:4
4
作者 Ma Qinsheng Cao Yang +1 位作者 Yang Jun Wang Min 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第6期1378-1383,共6页
In order to deal with the limitations during the register transfer level verification, a new functional verification method based on the random testing for the system-level of system-on-chip is proposed.The validity o... In order to deal with the limitations during the register transfer level verification, a new functional verification method based on the random testing for the system-level of system-on-chip is proposed.The validity of this method is proven theoretically.Specifically, testcases are generated according to many approaches of randomization.Moreover, the testbench for the system-level verification according to the proposed method is designed by using advanced modeling language.Therefore, under the circumstances that the testbench generates testcases quickly, the hardware/software co-simulation and co-verification can be implemented and the hardware/software partitioning planning can be evaluated easily.The comparison method is put to use in the evaluation approach of the testing validity.The evaluation result indicates that the efficiency of the partition testing is better than that of the random testing only when one or more subdomains are covered over with the area of errors, although the efficiency of the random testing is generally better than that of the partition testing.The experimental result indicates that this method has a good performance in the functional coverage and the cost of testing and can discover the functional errors as soon as possible. 展开更多
关键词 VLSI circuit VERIFICATION random process FUNCTION testING SYSTEM-ON-CHIP system-level.
在线阅读 下载PDF
EMPIRICAL BAYES TEST PROBLEMS OF VARIANCE COMPONENTS IN RANDOM EFFECTS MODEL 被引量:3
5
作者 韦来生 张伟平 《Acta Mathematica Scientia》 SCIE CSCD 2005年第2期274-282,共9页
Bayes decision rule of variance components for one-way random effects model is derived and empirical Bayes (EB) decision rules are constructed by kernel estimation method. Under suitable conditions, it is shown that t... Bayes decision rule of variance components for one-way random effects model is derived and empirical Bayes (EB) decision rules are constructed by kernel estimation method. Under suitable conditions, it is shown that the proposed EB decision rules are asymptotically optimal with convergence rates near O(n-1/2). Finally, an example concerning the main result is given. 展开更多
关键词 Empirical Bayes test variance components random effects model convergence rates
在线阅读 下载PDF
Random-Like Testing of Very Large Scale Integration Circuit 被引量:2
6
作者 Xu Shiyi (School of Computer Engineering and Science) 《Advances in Manufacturing》 SCIE CAS 1998年第4期21-25,共5页
A new approach to improve the test efficiency of random testing is presented in this paper. In conventional random testing, each test pattern is selected randomly regardless of the tests previously generated. This pap... A new approach to improve the test efficiency of random testing is presented in this paper. In conventional random testing, each test pattern is selected randomly regardless of the tests previously generated. This paper introduces the concept of random like testing. The method provided appears to have the same concepts as used in random testing,but actually takes an opposite way to it in order to improve the efficiency of random testing.In a random like testing sequence, the total distance among all test patterns is chosen to be maximal so that the fault sets detected by one test pattern are as different as possible from that detected by the tests previously applied. The procedure to construct a random like testing sequence (RLTS) is described in detail. Theorems to justify the effectiveness and usefulness of the procedure presented are developed. Experimental results on benchmark circuits as well as on other circuit are also given to evaluate the performance of the new approach. 展开更多
关键词 random testing fault coverage Hamming distance total Hamming distance
在线阅读 下载PDF
TESTING FOR VARYING DISPERSION OF LONGITUDINAL BINOMIAL DATA IN NONLINEAR LOGISTIC MODELS WITH RANDOM EFFECTS 被引量:2
7
作者 林金官 韦博成 《Acta Mathematica Scientia》 SCIE CSCD 2004年第4期559-568,共10页
In this paper, it is discussed that two tests for varying dispersion of binomial data in the framework of nonlinear logistic models with random effects, which are widely used in analyzing longitudinal binomial data. O... In this paper, it is discussed that two tests for varying dispersion of binomial data in the framework of nonlinear logistic models with random effects, which are widely used in analyzing longitudinal binomial data. One is the individual test and power calculation for varying dispersion through testing the randomness of cluster effects, which is extensions of Dean(1992) and Commenges et al (1994). The second test is the composite test for varying dispersion through simultaneously testing the randomness of cluster effects and the equality of random-effect means. The score test statistics are constructed and expressed in simple, easy to use, matrix formulas. The authors illustrate their test methods using the insecticide data (Giltinan, Capizzi & Malani (1988)). 展开更多
关键词 Longitudinal binomial data logistic regression nonlinear models power calculation random effects score test varying dispersion
在线阅读 下载PDF
Generation of 3D random meso-structure of soil-rock mixture and its meso-structural mechanics based on numerical tests 被引量:4
8
作者 徐文杰 张海洋 +1 位作者 介玉新 于玉贞 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第2期619-630,共12页
The mesoscopic failure mechanism and the macro-mechanical characteristics of soil-rock mixture(S-RM) under external load are largely controlled by S-RM's meso-structural features. The objective of this work is to ... The mesoscopic failure mechanism and the macro-mechanical characteristics of soil-rock mixture(S-RM) under external load are largely controlled by S-RM's meso-structural features. The objective of this work is to improve the three-dimensional technology for the generation of the random meso-structural models of S-RM, for randomly generating irregular rock blocks in S-RM with different shapes, sizes, and distributions according to the characteristics of the rock blocks' size distribution. Based on the new improved technology, a software system named as R-SRM3 D for generation and visualization of S-RM is developed. Using R-SRM3 D, a three-dimensional meso-structural model of S-RM is generated and used to study the meso-mechanical behavior through a series of true-triaxial numerical tests. From the numerical tests, the following conclusions are obtained. The meso-stress field of S-RM is influenced by the distribution of the internal rock blocks, and the macro-mechanical characteristics of S-RM are anisotropic in 3D; the intermediate principal stress and the soil-rock interface properties have significant influence on the macro strength of S-RM. 展开更多
关键词 soil-rock mixture(S-RM) three dimensional meso-structure meso-structural mechanics(M-SM) true-triaxial numerical test random simulation
在线阅读 下载PDF
OUTLIER TEST IN RANDOMIZED LINEAR MODEL 被引量:2
9
作者 XIANGLIMING SHILEI 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 1994年第1期65-75,共11页
In this papert we give an approach for detecting one or more outliers inrandomized linear model.The likelihood ratio test statistic and its distributions underthe null hypothesis and the alternative hypothesis are giv... In this papert we give an approach for detecting one or more outliers inrandomized linear model.The likelihood ratio test statistic and its distributions underthe null hypothesis and the alternative hypothesis are given. Furthermore,the robustnessof the test statistic in a certain sense is proved. Finally,the optimality properties of thetest are derived. 展开更多
关键词 randomized Linear Model.Outliers Likelihood Ratio test UNIFORMLY
在线阅读 下载PDF
TESTING OF CORRELATION AND HETEROSCEDASTICITY IN NONLINEAR REGRESSION MODELS WITH DBL(p,q,1) RANDOM ERRORS
10
作者 刘应安 韦博成 《Acta Mathematica Scientia》 SCIE CSCD 2008年第3期613-632,共20页
Chaos theory has taught us that a system which has both nonlinearity and random input will most likely produce irregular data. If random errors are irregular data, then random error process will raise nonlinearity (K... Chaos theory has taught us that a system which has both nonlinearity and random input will most likely produce irregular data. If random errors are irregular data, then random error process will raise nonlinearity (Kantz and Schreiber (1997)). Tsai (1986) introduced a composite test for autocorrelation and heteroscedasticity in linear models with AR(1) errors. Liu (2003) introduced a composite test for correlation and heteroscedasticity in nonlinear models with DBL(p, 0, 1) errors. Therefore, the important problems in regression model axe detections of bilinearity, correlation and heteroscedasticity. In this article, the authors discuss more general case of nonlinear models with DBL(p, q, 1) random errors by score test. Several statistics for the test of bilinearity, correlation, and heteroscedasticity are obtained, and expressed in simple matrix formulas. The results of regression models with linear errors are extended to those with bilinear errors. The simulation study is carried out to investigate the powers of the test statistics. All results of this article extend and develop results of Tsai (1986), Wei, et al (1995), and Liu, et al (2003). 展开更多
关键词 DBL(p Q 1) random errors nonlinear regression models score test HETEROSCEDASTICITY CORRELATION
在线阅读 下载PDF
Randomized trial estimating effects of hypnosis versus progressive muscle relaxation on medical students’test anxiety and attentional bias
11
作者 Yang Zhang Xin-Xin Yang +5 位作者 Jing-Yi Luo Meng Liang Ni Li Qian Tao Li-Jun Ma Xiao-Ming Li 《World Journal of Psychiatry》 SCIE 2022年第6期801-813,共13页
BACKGROUND Test anxiety is prevalent among medical students and leads to impaired academic performance.Test-related attentional bias has been identified as an important maintaining factor in test-anxious individuals.A... BACKGROUND Test anxiety is prevalent among medical students and leads to impaired academic performance.Test-related attentional bias has been identified as an important maintaining factor in test-anxious individuals.AIM To evaluate whether hypnosis and progressive muscle relaxation(PMR)could modify medical college students’test anxiety and attentional bias.METHODS A total of 598 medical students were screened.The participants were divided into higher and lower test anxiety groups according to their scores on the test anxiety scale(TAS).Ninety medical college students with high TAS score were randomly assigned to a hypnosis or PMR group.Another 45 students with low TAS score were included,forming a baseline control group.The intervention was conducted weekly for 6 wk,and each session lasted approximately 30 min.The total intervention time and the number of intervention sessions for the hypnosis and PMR groups were equal.Data were collected at the pretest,posttest,and 2-mo follow-up.RESULTS Hypnosis group participants had a significantly lower TAS score at posttest(t=-21.827,P<0.001)and at follow-up(t=-14.824,P<0.001),compared to that at pretest.PMR group participants also had a significantly lower TAS score at posttest(t=-10.777,P<0.001)and at follow-up(t=-7.444,P<0.001),compared to that at pretest.At the posttest level,the hypnosis group had a significantly lower TAS score than the PMR group(t=-3.664,P<0.001).At the follow-up level,the hypnosis group also had a significantly lower TAS score than the PMR group(t=-2.943,P=0.004).Clinically significant improvement was found in both the hypnosis and PMR groups(hypnosis=64.0%;PMR=62.22%).Hypnosis was more effective than PMR in reducing test anxiety among medical college students.Hypnosis could modify attentional bias toward threatening stimuli,but PMR could not.CONCLUSION These results suggest that attentional bias plays an important role in test anxiety treatment. 展开更多
关键词 test anxiety HYPNOSIS Progressive muscle relaxation Attentional bias randomized controlled trial
暂未订购
Research on the Computer Network Protocol Test Model based on Genetic and Random Walk Algorithm
12
作者 Ping Li 《International Journal of Technology Management》 2016年第8期39-42,共4页
In this paper, we conduct research on the computer network protocol test model based on genetic and random walk algorithm.Network protocol is the abstract concept, is important in the process of the development of net... In this paper, we conduct research on the computer network protocol test model based on genetic and random walk algorithm.Network protocol is the abstract concept, is important in the process of the development of network system. Fully understand and grasp of thenetwork protocols for managers is there is a big diffi cult. Network covert channel is the evaluation of intrusion detection system and fi rewallsecurity performance of an important means, the paper will start from the angle of the attacker, the fl aws of the research, and use this kind ofdefect to realize network covert channel, the random walk algorithm will be feasible for dealing with this issue. For achieving this, we integratethe genetic and random walk algorithm for systematic optimization. 展开更多
关键词 Computer Network Protocol test Model Genetic and random Walk Algorithm.
在线阅读 下载PDF
Robustness self-testing of states and measurements in the prepare-and-measure scenario with 3 → 1 random access code
13
作者 Shi-Hui Wei Fen-Zhuo Guo +1 位作者 Xin-Hui Li Qiao-Yan Wen 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第7期144-151,共8页
Recently, Tavakoli et al.proposed a self-testing scheme in the prepare-and-measure scenario, showing that self-testing is not necessarily based on entanglement and violation of a Bell inequality [Phys.Rev.A 98 062307(... Recently, Tavakoli et al.proposed a self-testing scheme in the prepare-and-measure scenario, showing that self-testing is not necessarily based on entanglement and violation of a Bell inequality [Phys.Rev.A 98 062307(2018)].They realized the self-testing of preparations and measurements in an N → 1(N ≥ 2) random access code(RAC), and provided robustness bounds in a 2 → 1 RAC.Since all N → 1 RACs with shared randomness are combinations of 2 → 1 and 3 → 1 RACs, the3 → 1 RAC is just as important as the 2 → 1 RAC.In this paper, we find a set of preparations and measurements in the3 → 1 RAC, and use them to complete the robustness self-testing analysis in the prepare-and-measure scenario.The method is robust to small but inevitable experimental errors. 展开更多
关键词 ROBUSTNESS SELF-testING prepare-and-measure SCENARIO 3 1 random access CODE
原文传递
Use of Random Regression Test-Day Model to Estimate Genetic Parameters of Milk Yield in Holstein Cows
14
作者 Yaser Fazel Masoud Asadi Fozi +4 位作者 Ali Esmailizadeh Fatemeh Fazel Ahmad Massoud Niazi Shahpoor Rahmati Mohammad Ibrahim Qasimi 《Open Journal of Animal Sciences》 2018年第1期27-38,共12页
(Co) variance components and genetic parameters were estimated for milk yield of Iranian Holstein cows. A total number of 68,945 milk test-day records of first, second and third lactations of 8515 animals from 100 sir... (Co) variance components and genetic parameters were estimated for milk yield of Iranian Holstein cows. A total number of 68,945 milk test-day records of first, second and third lactations of 8515 animals from 100 sires and 7743 dams originated from 34 herds collected during 2007 to 2009 by Iranian animal breeding center were used. The ASReml computer program was used to analyze the milk test-day records using the random regression procedure. Herd test date (HTD), milking times per day (milking frequency), number of lactations, year of birth, year of calving, age of animal at calving and days in milk (DIM) considered as fixed effects and additive genetic effects and animal permanent environmental effects were considered as the random effects. Additive genetic variance, animal permanent environment variance, residual variance, phenotypic variance, heritability and repeatability were estimated during different months of lactation between 5.7 - 19.6, 15.3 - 27.1, 31.4 - 17.2, 45.8 - 64.83, 0.1 - 0.32 and 0.4 - 0.6, respectively. Genetic correlation and phenotypic correlation were also estimated between months of lactation in range of -0.35 - 0.98 and 0.03 - 0.67, respectively. Genetic correlation and phenotypic correlation both showed the same changing pattern and they decreased as the interval between months of lactation increased. 展开更多
关键词 GENETIC Parameters random Regression Model test-Day RECORDS MILK Yield HOLSTEIN COWS
暂未订购
Epstein-Barr病毒与强直性脊柱炎互作:基于UK Biobank与FinnGen数据库的分析
15
作者 刘恩旭 孙钰 +3 位作者 段嘉豪 杨雷 蒋浩波 杨少锋 《中国组织工程研究》 北大核心 2026年第17期4542-4547,共6页
背景:Epstein-Barr病毒(EBV)作为一种人类疱疹病毒,在人群中广泛存在。既往观察性研究提示EBV感染与强直性脊柱炎相关,但传统方法因混杂因素和反向因果偏倚无法明确因果关联。阐明EBV与强直性脊柱炎的因果关联,不仅有助于揭示强直性脊... 背景:Epstein-Barr病毒(EBV)作为一种人类疱疹病毒,在人群中广泛存在。既往观察性研究提示EBV感染与强直性脊柱炎相关,但传统方法因混杂因素和反向因果偏倚无法明确因果关联。阐明EBV与强直性脊柱炎的因果关联,不仅有助于揭示强直性脊柱炎的免疫致病机制,也为靶向EBV的预防策略提供理论依据。目的:通过双向孟德尔随机化分析,探讨EBV感染与强直性脊柱炎之间的双向因果关系。方法:基于欧洲人群的全基因组关联研究汇总数据,采用双向双样本孟德尔随机化分析,结合广义汇总数据孟德尔随机化与传统方法(逆方差加权、MR-Egger、加权中位数),探讨EBV感染与强直性脊柱炎的双向因果关系。EBV抗体(EA-D、EBNA-1、VCA p18、ZEBRA)数据来源于UK Biobank数据库,强直性脊柱炎数据来自FinnGen数据库。工具变量筛选遵循全基因组显著性(P<5×10^(-6))、排除连锁不平衡及混杂相关单核苷酸多态性(吸烟、类风湿关节炎、银屑病)。统计检验采用Bonferroni校正(显著性阈值P=6.3×10^(-3)),并通过异质性(Cochran’s Q)、多效性(MR-Egger截距、MR-PRESSO)及稳健性(留一法)分析验证结果的可靠性。广义汇总数据孟德尔随机化方法进一步通过HEIDI-outlier检验(P<0.01)剔除多效性单核苷酸多态性,确保因果推断的准确性。结果与结论:①双向孟德尔随机化分析显示,EBV感染显著增加强直性脊柱炎发病风险:EBNA-1抗体水平升高与强直性脊柱炎风险呈正相关(OR=1.41,95%CI:1.14-1.76,P=0.002),而ZEBRA抗体效应更强(OR=1.56,95%CI:1.31-1.85,P=5.4×10^(-7)),提示EBV潜伏期(EBNA-1)与裂解期(ZEBRA)感染均可能通过交叉免疫反应驱动强直性脊柱炎发生;②反向因果分析显示,强直性脊柱炎与EBV裂解期标志物EA-D抗体呈负相关(OR=0.96,95%CI:0.94-0.98,P=3.25×10^(-4)),表明强直性脊柱炎患者免疫状态可能抑制EBV再激活;③所有结果通过异质性、多效性及稳健性检验,无潜在偏倚;④此研究基于国际数据库和欧洲人群数据,首次证实EBV感染是强直性脊柱炎的独立因果风险因素。尽管人群遗传背景存在差异,但欧洲人群的发现为解析强直性脊柱炎的共性免疫机制提供了关键线索。因此,未来需结合中国本土队列验证结果,探索EBV与中国人群强直性脊柱炎的分子互作特征。此外,广义汇总数据孟德尔随机化方法的应用为利用公共全基因组关联研究数据开展因果推断提供了范例,可推动中国研究者高效挖掘疾病风险因素,助力精准医学发展。 展开更多
关键词 强直性脊柱炎 EPSTEIN-BARR病毒 抗体 因果关系 广义汇总数据孟德尔随机化 异质性依赖工具检验 工程化组织构建
暂未订购
炎症因子、白细胞与腰椎间盘突出症的关系
16
作者 辜山 张龙 李志刚 《中国组织工程研究》 北大核心 2026年第18期4782-4790,共9页
背景:腰椎间盘突出症是一种临床高发的脊柱疾病,现有研究证据提示细胞因子、白细胞与腰椎间盘突出症发生、发展有重要联系,但具体机制尚不明确。目的:应用孟德尔随机化分析,探究细胞因子、白细胞与腰椎间盘突出症的因果关系。方法:选取G... 背景:腰椎间盘突出症是一种临床高发的脊柱疾病,现有研究证据提示细胞因子、白细胞与腰椎间盘突出症发生、发展有重要联系,但具体机制尚不明确。目的:应用孟德尔随机化分析,探究细胞因子、白细胞与腰椎间盘突出症的因果关系。方法:选取GWAS Catalog数据库中的91个细胞因子数据和来自血细胞联盟的6种白细胞数据为暴露,最新版R12芬兰数据库中的腰椎间盘突出症数据为结局,采用双向两样本孟德尔随机化和全基因组关联研究共定位分析方法探寻细胞因子、白细胞与腰椎间盘突出症的因果关系。采用Steiger检验、Cochran’s Q检验、MR-Egger截距评估、留一法分析等敏感性检验方法验证结果的准确性。主要使用逆方差加权法进行统计分析。结果与结论:①嗜碱性粒细胞和嗜酸性粒细胞与腰椎间盘突出症具有因果关系(OR=0.93,95%CI:0.87-0.99;OR=0.94,95%CI:0.88-1.00);②S100钙结合蛋白A12水平(OR=0.74,95%CI:0.55-1.00)、成纤维细胞生长因子水平(OR=1.03,95%CI:1.00-1.07)、白细胞介素20受体α蛋白水平(OR=1.09,95%CI:1.04-1.15)、白细胞介素6水平(OR=1.07,95%CI:1.00-1.13)、白细胞介素7水平(OR=1.08,95%CI:1.01-1.16)、干细胞因子水平(OR=1.05,95%CI:1.01-1.09)、白细胞介素2水平(OR=0.94,95%CI:0.89-0.99)与腰椎间盘突出症具有因果关系;③共定位分析发现,干细胞因子水平H3+H4=0.80,其中最显著的单核苷酸多态性为rs6073966。结果表明,嗜碱性粒细胞、嗜酸性粒细胞、S100钙结合蛋白A12、成纤维细胞生长因子、白细胞介素20受体α蛋白、白细胞介素2、白细胞介素6、白细胞介素7、干细胞因子对腰椎间盘突出症具有单向因果作用;干细胞因子和腰椎间盘突出症之间可能存在相关通路。 展开更多
关键词 细胞因子 炎症 双向两样本孟德尔随机化 共定位 Steiger检验 腰椎间盘突出症
暂未订购
Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial 被引量:16
17
作者 Wang Xianliang Hou Yazhu +19 位作者 Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2017年第6期756-766,共11页
OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, c... OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. 展开更多
关键词 Heart failure Medicine Chinese tradi-tional WALK test randomIZED CONTROLLED trail
原文传递
Non-destructive testing and pre-warning analysis on the quality of bolt support in deep roadways of mining districts 被引量:15
18
作者 Zhang Houquan Miao Xiexing +2 位作者 Zhang Guimin Wu Yu Chen Yanlong 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2017年第6期989-998,共10页
The bolt support quality of coal roadways is one of the important factors for the efficiency and security of coal production. By means of a self-developed technique and equipment of random non-destructive testing, non... The bolt support quality of coal roadways is one of the important factors for the efficiency and security of coal production. By means of a self-developed technique and equipment of random non-destructive testing, non-destructive detection and pre-warning analysis on the quality of bolt support in deep roadways of mining districts were performed in a number of mining areas. The measured data were obtained in the detection instances of abnormal in-situ stress and support invalidation etc. The corresponding relation between axial bolt load variation and roadway surrounding rock deformation and stability was summarized in different mining service stages. Pre-warning technology of roadway surrounding rock stability is proposed based on the detection of axial bolt load. Meanwhile, pre-warning indicators of axial bolt load in different mining service stages are offered and some successful pre-warning cases are also illustrated.The research results show that the change rules of axial bolt load in different mining service stages are quite similar in different mining areas. The change of axial bolt load is in accord with the adjustment of surrounding rock stress, which can consequently reflect the deformation and stability state of roadway surrounding rock. Through the detection of axial bolt load in different sections of roadways, the status of real-time bolt support quality can be reflected; meanwhile, the rationality of bolt support design can be evaluated which provides reference for bolting parameters optimization. 展开更多
关键词 Deep roadways BOLT support QUALITY random NONDESTRUCTIVE testing SURROUNDING ROCK stability Prediction and pre-warning
在线阅读 下载PDF
CONSISTENCY OF MLE OF THE PARAMETER OF EXPONENTIAL LIFETIME DISTRIBUTION FOR RANDOM CENSORING MODEL WITH INCOMPLETE INFORMATION 被引量:18
19
作者 YE ERHUA 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 1995年第4期379-386,共8页
In this paper, we have discussed a random censoring test with incomplete information, and proved that the maximum likelihood estimator(MLE) of the parameter based on the randomly censored data with incomplete informat... In this paper, we have discussed a random censoring test with incomplete information, and proved that the maximum likelihood estimator(MLE) of the parameter based on the randomly censored data with incomplete information in the case of the exponential distribution has the strong consistency. 展开更多
关键词 random censoring test with incomplete information exponential distribution maximum likelihood estimator consistency.
在线阅读 下载PDF
ON CHOVER'S LIL FOR THE WEIGHTED SUMS OF STABLE RANDOM VARIABLES 被引量:5
20
作者 陈平炎 余旌胡 《Acta Mathematica Scientia》 SCIE CSCD 2003年第1期74-82,共9页
Let {Xn,n ≥ 1} be a sequence of α-stable random variables(0 < α < 2), {ani,1 ≤ i≤ n, n≥1} be an array of constant real numbers. Under some restriction of {ani,1 ≤ i ≤ n,n≥1}, the authors discuss the int... Let {Xn,n ≥ 1} be a sequence of α-stable random variables(0 < α < 2), {ani,1 ≤ i≤ n, n≥1} be an array of constant real numbers. Under some restriction of {ani,1 ≤ i ≤ n,n≥1}, the authors discuss the integral test for the weighted partial sums {Σi=1naniXi,n ≥ 1}, and obtain the Chover's laws of iterated logarithm(LIL) as corollaries. 展开更多
关键词 Stable random variable integral test LIL
在线阅读 下载PDF
上一页 1 2 80 下一页 到第
使用帮助 返回顶部