The correlation between the longitudinal crack occurrence and integrated heat transfer of the mold with data mining methods was investigated.Firstly,three kinds of support vector machine models based on principal comp...The correlation between the longitudinal crack occurrence and integrated heat transfer of the mold with data mining methods was investigated.Firstly,three kinds of support vector machine models based on principal component analysis with different input features were established to explore the effect of integrated heat transfer on the accuracy of the prediction model for the longitudinal crack.The results show that the accuracy was improved while features including mean and standard deviation of integrated heat transfer were added.Then,the difference in integrated heat transfer between defect and normal samples under the same process parameters was quantitatively compared.Compared with normal samples,the temperature difference of cooling water for defect samples decreased by 0.65%,and the temperature difference fluctuation increased by 31.1%.Finally,the literature data were used to provide support for the quantitative correlation according to defect formation mechanism.A new criterion for the prediction of longitudinal crack and a discovering method for correlation between product quality and process parameters in the manufacturing industry have been provided.展开更多
The secondary flow attracts wide concerns in the aeroengine compressors since it has become one of the major loss sources in modern high-performance compressors.But the research about the quantitative relationship bet...The secondary flow attracts wide concerns in the aeroengine compressors since it has become one of the major loss sources in modern high-performance compressors.But the research about the quantitative relationship between secondary flow and inviscid blade force needs to be more detailed.In this paper,a database of 889 three-dimensional linear cascades was built.An indicator,called Secondary Flow Intensity(SFI),was used to express the loss caused by secondary flow.The quantitative relationship between the SFI and inviscid blade force deterioration was researched.Blade oil flow and Computation Fluid Dynamics(CFD)results of some cascades were also used to cross-validate.Results suggested that all numerical cascade cases can be divided into 3 clusters by the SFI,which are called Clusters A,B and C in the order of the increasing SFI indicator.The corner stall,known as the strong corner separation,only happens when the SFI is high.Both calculations and oil flow experiments show that the SFI would stay at a low level if the vortex core at the endwall surface does not appear.The strong interaction of Kutta condition and endwall cross-flow is considered the dominant mechanism of higher secondary flow losses,rather than the secondary flow penetration depth on the suction surface.In conclusion,the inviscid blade force spanwise deterioration is strongly related to the SFI.The correlation of the SFI and spanwise inviscid blade force deterioration is given in this paper.The correlation could provide a quantitative reference for estimating secondary flow losses in the design.展开更多
Based on the major gene and polygene mixed inheritance model for multiple correlated quantitative traits, the authors proposed a new joint segregation analysis method of major gene controlling multiple correlated quan...Based on the major gene and polygene mixed inheritance model for multiple correlated quantitative traits, the authors proposed a new joint segregation analysis method of major gene controlling multiple correlated quantitative traits, which include major gene detection and its effect and variation estimation. The effect and variation of major gene are estimated by the maximum likelihood method implemented via expectation-maximization （EM） algorithm. Major gene is tested with the likelihood ratio （LR） test statistic. Extensive simulation studies showed that joint analysis not only increases the statistical power of major gene detection but also improves the precision and accuracy of major gene effect estimates. An example of the plant height and the number of tiller of F2 population in rice cross Duonieai x Zhonghua 11 was used in the illustration. The results indicated that the genetic difference of these two traits in this cross refers to only one pleiotropic major gene. The additive effect and dominance effect of the major gene are estimated as -21.3 and 40.6 cm on plant height, and 22.7 and -25.3 on number of tiller, respectively. The major gene shows overdominance for plant height and close to complete dominance for number of tillers.展开更多
O-Aryl O-ethyl N-isopropyl phosphoramidothioates (Ⅰ) have herbicidal activity. In order to study the relationship between structures and activities of these compounds, more than thirty compounds (Ⅰ) have been prepar...O-Aryl O-ethyl N-isopropyl phosphoramidothioates (Ⅰ) have herbicidal activity. In order to study the relationship between structures and activities of these compounds, more than thirty compounds (Ⅰ) have been prepared by the reaction of O-aryl O-ethyl phosphorochloridothioates with isopropylamine in the presence of 40% NaOH at 0℃. The intermediates, phosphorochloridothioates, were prepared separately from a large excess of O-ethyl Phosphorodichloridothioate and various substituted phenols in the presence of 40% NaOH and a catalyrical amount of Et_3N at 0—5℃. As a result, higher purity and good yields were obtained.It was found that the activity of these compounds was highly dependent upon the substituents attached to the benzene ring with respect to the characteristic parameters π, E_s, σ and F by using Hansch's equation.It was indicated that hydrophobic (π), steric (E_s), and electronic (σ and F) effects of the substituents on the ring in those molecules seem to be of considerable importance in determining their biological activity.By replacing π with △R_m and a and F with △δ_p, respectively, in regression analysis a better correlation was obtained. Both △R_m and △δ_p were experimental data. The former was calculated from R_f measured with reversed-phase thin-layer chromatography and the latter was obtained from the difference between the chemical shifts of the ^(31)P NMR of compounds(Ⅰ) and that of the parent compound.展开更多
Objective To investigate whether correlation existsbetween quantitative perfusion parameters obtained from dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and different prognostic factors or immunohistoch...Objective To investigate whether correlation existsbetween quantitative perfusion parameters obtained from dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and different prognostic factors or immunohistochemical subtypes of breast cancers.Methods A retrospective analysis of DCE-MRI was performed in展开更多
Quantitative analysis of P53 protein expression was performed on paraffin-embedded tissues from 55 smooth muscle tumors of the gastrointestinal tract, using immunofluo-rescence and flow cytometry. No positive expressi...Quantitative analysis of P53 protein expression was performed on paraffin-embedded tissues from 55 smooth muscle tumors of the gastrointestinal tract, using immunofluo-rescence and flow cytometry. No positive expression was found in normal smooth muscle tissues of the gastrointestinal tract. Over-expression of P53 gene was found in a significantly higher proportion in leiomyosarcomas (90%) and potentially malignant smooth muscle tumors (75%) as compared to leiomyomas (14%) (P< 0.005). The quantitation of P53 expression was found to be progressively enhanced in the sequence from leiomyoma through potentially malignant smooth muscle tumor to leiomyosarcoma (P< 0.005). It was markedly over-expressed when the mitotic counts ranged from one to more than one per 10 high power fields (P< 0.005) or the mild cytologic atypia was found (P< 0.005). The five-year survival rate was significantly higher in patients with low-expression of P53 than in those with over-expression of P53 (P< 0.005). It was suggested that P53 over-expression might be associated with the transformation of leiomyoma into leiomyosarcoma and could be used as an objective parameter in distinguishing the malignant from the benign and predicting the prognosis of patients with smooth muscle rumors of the gastrointestinal tract.展开更多
Xinjiang Region of China is one of the most typical and representative arid areas worldwide,along with severe soil salinization issue.Planting spring wheat and sequential cropping silage corn in Northern Xinjiang usin...Xinjiang Region of China is one of the most typical and representative arid areas worldwide,along with severe soil salinization issue.Planting spring wheat and sequential cropping silage corn in Northern Xinjiang using drip irrigation has become an effective way to relieve soil salinity stress,which improves the simple agricultural structure in the past and ensures food security in this area.However,neither the effects of different soil salinities on the growth and yield of spring wheat and silage corn,nor their desalination effect correspondingly was clear until now.Therefore,a pot experiment was conducted at Shihezi,Xinjiang from March to June 2015.The study aimed to establish the quantitative correlations between the parameters mentioned above and came up with the appropriate soil salinity threshold in Northern Xinjiang area.The results confirmed that the soils in all treatments were desalinated after the whole growth period,and the decreasing rates varied within 18.89%-44.08%and 11.06%-30.83%for two plants,which showed linear and quadratic correlations with initial soil salinity,respectively(R^(2)>0.92^(**),p<0.05).Meanwhile,higher soil salinity would inhibit crop growth and yield,and the initial soil salinity also represented the negative quadratic correlations with growth parameters(R^(2)>0.92^(**),p<0.01).The inhibition effect was enhanced with larger initial soil salinity.After the comprehensive consideration of soil salinity variation,crop growth and yield,the initial soil salinity was recommended under 8.91 g/kg and 5.54 g/kg to plant spring wheat and sequential cropping silage corn in Northern Xinjiang using drip irrigation.展开更多
基金the support from National Natural Science Foundation of China(52274318).
文摘The correlation between the longitudinal crack occurrence and integrated heat transfer of the mold with data mining methods was investigated.Firstly,three kinds of support vector machine models based on principal component analysis with different input features were established to explore the effect of integrated heat transfer on the accuracy of the prediction model for the longitudinal crack.The results show that the accuracy was improved while features including mean and standard deviation of integrated heat transfer were added.Then,the difference in integrated heat transfer between defect and normal samples under the same process parameters was quantitatively compared.Compared with normal samples,the temperature difference of cooling water for defect samples decreased by 0.65%,and the temperature difference fluctuation increased by 31.1%.Finally,the literature data were used to provide support for the quantitative correlation according to defect formation mechanism.A new criterion for the prediction of longitudinal crack and a discovering method for correlation between product quality and process parameters in the manufacturing industry have been provided.
基金the National Science and Technology Major Project,China(Nos.2017-I-0005-0006&2019-II-0020-0041).
文摘The secondary flow attracts wide concerns in the aeroengine compressors since it has become one of the major loss sources in modern high-performance compressors.But the research about the quantitative relationship between secondary flow and inviscid blade force needs to be more detailed.In this paper,a database of 889 three-dimensional linear cascades was built.An indicator,called Secondary Flow Intensity(SFI),was used to express the loss caused by secondary flow.The quantitative relationship between the SFI and inviscid blade force deterioration was researched.Blade oil flow and Computation Fluid Dynamics(CFD)results of some cascades were also used to cross-validate.Results suggested that all numerical cascade cases can be divided into 3 clusters by the SFI,which are called Clusters A,B and C in the order of the increasing SFI indicator.The corner stall,known as the strong corner separation,only happens when the SFI is high.Both calculations and oil flow experiments show that the SFI would stay at a low level if the vortex core at the endwall surface does not appear.The strong interaction of Kutta condition and endwall cross-flow is considered the dominant mechanism of higher secondary flow losses,rather than the secondary flow penetration depth on the suction surface.In conclusion,the inviscid blade force spanwise deterioration is strongly related to the SFI.The correlation of the SFI and spanwise inviscid blade force deterioration is given in this paper.The correlation could provide a quantitative reference for estimating secondary flow losses in the design.
基金This research was supported by the National Natural Science Foundation of China to Xu Chenwu （39900080, 30270724 and 30370758）.
文摘Based on the major gene and polygene mixed inheritance model for multiple correlated quantitative traits, the authors proposed a new joint segregation analysis method of major gene controlling multiple correlated quantitative traits, which include major gene detection and its effect and variation estimation. The effect and variation of major gene are estimated by the maximum likelihood method implemented via expectation-maximization （EM） algorithm. Major gene is tested with the likelihood ratio （LR） test statistic. Extensive simulation studies showed that joint analysis not only increases the statistical power of major gene detection but also improves the precision and accuracy of major gene effect estimates. An example of the plant height and the number of tiller of F2 population in rice cross Duonieai x Zhonghua 11 was used in the illustration. The results indicated that the genetic difference of these two traits in this cross refers to only one pleiotropic major gene. The additive effect and dominance effect of the major gene are estimated as -21.3 and 40.6 cm on plant height, and 22.7 and -25.3 on number of tiller, respectively. The major gene shows overdominance for plant height and close to complete dominance for number of tillers.
文摘O-Aryl O-ethyl N-isopropyl phosphoramidothioates (Ⅰ) have herbicidal activity. In order to study the relationship between structures and activities of these compounds, more than thirty compounds (Ⅰ) have been prepared by the reaction of O-aryl O-ethyl phosphorochloridothioates with isopropylamine in the presence of 40% NaOH at 0℃. The intermediates, phosphorochloridothioates, were prepared separately from a large excess of O-ethyl Phosphorodichloridothioate and various substituted phenols in the presence of 40% NaOH and a catalyrical amount of Et_3N at 0—5℃. As a result, higher purity and good yields were obtained.It was found that the activity of these compounds was highly dependent upon the substituents attached to the benzene ring with respect to the characteristic parameters π, E_s, σ and F by using Hansch's equation.It was indicated that hydrophobic (π), steric (E_s), and electronic (σ and F) effects of the substituents on the ring in those molecules seem to be of considerable importance in determining their biological activity.By replacing π with △R_m and a and F with △δ_p, respectively, in regression analysis a better correlation was obtained. Both △R_m and △δ_p were experimental data. The former was calculated from R_f measured with reversed-phase thin-layer chromatography and the latter was obtained from the difference between the chemical shifts of the ^(31)P NMR of compounds(Ⅰ) and that of the parent compound.
文摘Objective To investigate whether correlation existsbetween quantitative perfusion parameters obtained from dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and different prognostic factors or immunohistochemical subtypes of breast cancers.Methods A retrospective analysis of DCE-MRI was performed in
文摘Quantitative analysis of P53 protein expression was performed on paraffin-embedded tissues from 55 smooth muscle tumors of the gastrointestinal tract, using immunofluo-rescence and flow cytometry. No positive expression was found in normal smooth muscle tissues of the gastrointestinal tract. Over-expression of P53 gene was found in a significantly higher proportion in leiomyosarcomas (90%) and potentially malignant smooth muscle tumors (75%) as compared to leiomyomas (14%) (P< 0.005). The quantitation of P53 expression was found to be progressively enhanced in the sequence from leiomyoma through potentially malignant smooth muscle tumor to leiomyosarcoma (P< 0.005). It was markedly over-expressed when the mitotic counts ranged from one to more than one per 10 high power fields (P< 0.005) or the mild cytologic atypia was found (P< 0.005). The five-year survival rate was significantly higher in patients with low-expression of P53 than in those with over-expression of P53 (P< 0.005). It was suggested that P53 over-expression might be associated with the transformation of leiomyoma into leiomyosarcoma and could be used as an objective parameter in distinguishing the malignant from the benign and predicting the prognosis of patients with smooth muscle rumors of the gastrointestinal tract.
基金support from the Natural Science Foundation of China(51169022)the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(2015BAD20B03)the High-level Scientific Research of Shihezi University(RCZX201433).
文摘Xinjiang Region of China is one of the most typical and representative arid areas worldwide,along with severe soil salinization issue.Planting spring wheat and sequential cropping silage corn in Northern Xinjiang using drip irrigation has become an effective way to relieve soil salinity stress,which improves the simple agricultural structure in the past and ensures food security in this area.However,neither the effects of different soil salinities on the growth and yield of spring wheat and silage corn,nor their desalination effect correspondingly was clear until now.Therefore,a pot experiment was conducted at Shihezi,Xinjiang from March to June 2015.The study aimed to establish the quantitative correlations between the parameters mentioned above and came up with the appropriate soil salinity threshold in Northern Xinjiang area.The results confirmed that the soils in all treatments were desalinated after the whole growth period,and the decreasing rates varied within 18.89%-44.08%and 11.06%-30.83%for two plants,which showed linear and quadratic correlations with initial soil salinity,respectively(R^(2)>0.92^(**),p<0.05).Meanwhile,higher soil salinity would inhibit crop growth and yield,and the initial soil salinity also represented the negative quadratic correlations with growth parameters(R^(2)>0.92^(**),p<0.01).The inhibition effect was enhanced with larger initial soil salinity.After the comprehensive consideration of soil salinity variation,crop growth and yield,the initial soil salinity was recommended under 8.91 g/kg and 5.54 g/kg to plant spring wheat and sequential cropping silage corn in Northern Xinjiang using drip irrigation.
