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Deep learning on chromatin profiles reveals the cis-regulatory sequence code of the rice genome
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作者 Xinkai Zhou Zhonghao Ruan +2 位作者 Chenlu Zhang Kerstin Kaufmann Dijun Chen 《Journal of Genetics and Genomics》 2025年第6期848-851,共4页
Rice(Oryza sativa)is a staple food for more than half of the world's population and a critical crop for global agriculture.Understanding the regulatory mechanisms that control gene expression in the rice genome is... Rice(Oryza sativa)is a staple food for more than half of the world's population and a critical crop for global agriculture.Understanding the regulatory mechanisms that control gene expression in the rice genome is fundamental for advancing agricultural productivity and food security.In mechanism,cis-regulatory elements(including promoters,enhancers,silencers,and insulators)are key DNA sequences whose activities determine the spatial and temporal expression patterns of nearby genes(Yocca and Edger,2022;Schmitz et al.,2022). 展开更多
关键词 cis regulatory elements deep learning chromatin profiles agricultural productivity rice genome cis regulatory sequence code gene expression food security
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Key technology of mine underground mobile positioning based on LiDAR and coded sequence pattern 被引量:4
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作者 WANG Zhi1, 2, WU Li-xin1, 2, LI Hui-ying3 1. College of Resources and Civil Engineering, Northeastern University, Shenyang 110004, China 2. Academy of Disaster Reduction and Emergency Management, Ministry of Civil Affairs and Ministry of Education, Beijing Normal University, Beijing 100875, China 3. College of Computer Science and Technology, Jilin University, Changchun 130012, China 《中国有色金属学会会刊:英文版》 CSCD 2011年第S3期570-576,共7页
Technologies of underground mobile positioning were proposed based on LiDAR data and coded sequence pattern landmarks for mine shafts and tunnels environment to meet the needs of fast and accurate positioning and navi... Technologies of underground mobile positioning were proposed based on LiDAR data and coded sequence pattern landmarks for mine shafts and tunnels environment to meet the needs of fast and accurate positioning and navigation of equipments in the mine underground without satellite navigation signals. A coded sequence pattern was employed for automatic matching of 3D scans. The methods of SIFT feature, Otsu segmentation and fast hough transformation were described for the identification, positioning and interpretation of the coded sequence patterns, respectively. The POSIT model was presented for speeding up computation of the translation and rotation parameters of LiDAR point data, so as to achieve automatic 3D mapping of mine shafts and tunnels. The moving positioning experiment was applied to evaluating the accuracy of proposed pose estimation method from LiDAR scans and coded sequence pattern landmarks acquired in an indoor environment. The performance was evaluated using ground truth data of the indoor setting so as to measure derivations with six degrees of freedom. 展开更多
关键词 LIDAR codeD sequence pattern mobile POSITIONING SLAM ALGORITHM POSIT ALGORITHM
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The structural analysis of protein sequences based on the quasi-amino acids code 被引量:2
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作者 朱平 唐旭清 徐振源 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第1期363-369,共7页
Proteomics is the study of proteins and their interactions in a cell. With the successful completion of the Human Cenome Project, it comes the postgenome era when the proteomics technology is emerging. This paper stud... Proteomics is the study of proteins and their interactions in a cell. With the successful completion of the Human Cenome Project, it comes the postgenome era when the proteomics technology is emerging. This paper studies protein molecule from the algebraic point of view. The algebraic system (∑, +, *) is introduced, where ∑ is the set of 64 codons. According to the characteristics of (∑, +, *), a novel quasi-amino acids code classification method is introduced and the corresponding algebraic operation table over the set ZU of the 16 kinds of quasi-amino acids is established. The internal relation is revealed about quasi-amino acids. The results show that there exist some very close correlations between the properties of the quasi-amino acids and the codon. All these correlation relationships may play an important part in establishing the logic relationship between codons and the quasi-amino acids during the course of life origination. According to Ma F et al (2003 J. Anhui Agricultural University 30 439), the corresponding relation and the excellent properties about amino acids code are very difficult to observe. The present paper shows that (ZU, +,×) is a field. Furthermore, the operational results display that the eodon tga has different property from other stop codons. In fact, in the mitochondrion from human and ox genomic codon, tga is just tryptophane, is not the stop codon like in other genetic code, it is the case of the Chen W C et al (2002 Acta Biophysiea Siniea 18(1) 87). The present theory avoids some inexplicable events of the 20 kinds of amino acids code, in other words it solves the problem of 'the 64 codon assignments of mRNA to amino acids is probably completely wrong' proposed by Yang (2006 Progress in Modern Biomedicine 6 3). 展开更多
关键词 algebraic operation quasi-amino acids code protein sequences structural analysis
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GAUSS PERIODS AND CYCLIC CODES FROM CYCLOTOMIC SEQUENCES OF SMALL ORDERS 被引量:1
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作者 Hu Liqin Yue Qin Zhu Xiaomeng 《Journal of Electronics(China)》 2014年第6期537-546,共10页
Let p =ef +1 be an odd prime with positive integers e and f. In this paper, we calculate the values of Gauss periods of order e =3, 4, 6 over a finite field GF(q), where q is a prime with q≠p. As applications, severa... Let p =ef +1 be an odd prime with positive integers e and f. In this paper, we calculate the values of Gauss periods of order e =3, 4, 6 over a finite field GF(q), where q is a prime with q≠p. As applications, several cyclotomic sequences of order e =3, 4, 6 are employed to construct a number of classes of cyclic codes over GF(q) with prime length. Under certain conditions, the linear complexity and reciprocal minimal polynomials of cyclotomic sequences are calculated, and the lower bounds on the minimum distances of these cyclic codes are obtained. 展开更多
关键词 sequence Cyclic code Weight distribution Gauss period CYCLOTOMY
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Pseudo-Random Sequences Generator Based on Discrete Hyperchaotic Systems 被引量:1
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作者 Li Changgang & Han Zhengzhi Department of Automation, Shanghai Jiaotong University, Shanghai 200030, P. R. China 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2003年第4期84-89,共6页
We first design a discrete hyperchaotic system via piece-wise linear state feedback. The states of the closed loop system are locally expanding in two directions but absolutely bounded on the whole, which implies hype... We first design a discrete hyperchaotic system via piece-wise linear state feedback. The states of the closed loop system are locally expanding in two directions but absolutely bounded on the whole, which implies hyperchaos. Then, we use three suchlike hyperchaotic systems with different feedback gain matrices to design a pseudo-random sequence generator (PRSG). Through a threshold function, three sub-sequences generated from the output of piecewise linear functions are changed into 0-1 sequences. Then, followed by XOR operation, an unpredictable pseudo-random sequence (PRS) is ultimately obtained. The analysis and simulation results indicate that the PRS, generated with hyperchaotic systems, has desirable statistical features. 展开更多
关键词 discrete hyperchaotic system piecewise linear state feedback pseudo-random sequences.
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HIERACHICAL STRUCTURES FOR GENERATING PSEUDO-RANDOM SEQUENCES AND ARRAYS
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作者 Shi Wenhong Chen Jinguang(Department of Radio Engineering, Fuzhou University, Fuzhou 350002) 《Journal of Electronics(China)》 1997年第1期20-26,共7页
This paper proposes new hierarchical structures for generating pseudorandom sequences and arrays. The principle of the structures is based on a new concept-multi-interleaving. It is the generalization of normal sequen... This paper proposes new hierarchical structures for generating pseudorandom sequences and arrays. The principle of the structures is based on a new concept-multi-interleaving. It is the generalization of normal sequence decimation(sampling). The kernal of the structures is a lower speed linear feedback shift register together with several high speed time-division multiplexers arranged hierarchically. These new structures have much higher speed compared with that of other schemes proposed before. 展开更多
关键词 pseudo-random sequenceS pseudo-random ARRAYS High-speed generation sequence DECIMATION
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USING ERROR-CORRECTING ENCODERS TO DESIGN LOCAL-RANDOM SEQUENCE GENERATORS
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作者 杨义先 《Journal of Electronics(China)》 1995年第1期9-14,共6页
This paper proved the statement that a good linear block encoder is in fact a good local-random sequence generator. Furthermore, this statement discovers the deep relationship between the error-correcting coding theor... This paper proved the statement that a good linear block encoder is in fact a good local-random sequence generator. Furthermore, this statement discovers the deep relationship between the error-correcting coding theory and the modern cryptography. 展开更多
关键词 Error-correcting CODING CRYPTOGRAPHY RANDOM sequenceS
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Adding Pseudo-Random Test Sequence Generator in the Test Simulator for DFT Approach
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作者 Afaq Ahmad Dawood Al-Abri Sayyid Samir AI-Busaidi 《Computer Technology and Application》 2012年第7期463-470,共8页
This paper presents modified version of a realistic test tool suitable to Design For Testability (DFT) and Built-ln Self Test (BIST) environments. A comprehensive tool is developed in the form of a test simulator.... This paper presents modified version of a realistic test tool suitable to Design For Testability (DFT) and Built-ln Self Test (BIST) environments. A comprehensive tool is developed in the form of a test simulator. The simulator is capable of providing a required goal of test for the Circuit Under Test (CUT). The simulator uses the approach of fault diagnostics with fault grading procedures to provide the optimum tests. The current version of the simulator embeds features of exhaustive and pseudo-random test generation schemes along with the search solutions of cost effective test goals. The simulator provides facilities of realizing all possible pseudo-random sequence generators with all possible combinations of seeds. The tool is developed on a common Personal Computer (PC) platform and hence no special software is required. Thereby, it is a low cost tool hence economical. The tool is very much suitable for determining realistic test sequences for a targeted goal of testing for any CUT. The developed tool incorporates flexible Graphical User Interface (GUI) procedures and can be operated without any special programming skill. The tool is debugged and tested with the results of many bench mark circuits. Further, this developed tool can be utilized for educational purposes for many courses such as fault-tolerant computing, fault diagnosis, digital electronics, and safe-reliable-testable digital logic designs. 展开更多
关键词 Digital system testing built-in self test design for testability test vector pseudo-random test sequence linear feedbackshift registers fault diagnosis fault collapsing realistic test fault cover iteration.
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CADGen:Computer-aided design sequence construction with a guided codebook learning
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作者 Shengdi Zhou Xiaoqiang Zan +1 位作者 Zhuqing Li Bin Zhou 《Digital Twins and Applications》 2024年第1期75-87,共13页
Computer-aided design(CAD)software continues to be a crucial tool in digital twin application and manufacturing,facilitating the design of various products.We present a novel CAD generation method,an agent that constr... Computer-aided design(CAD)software continues to be a crucial tool in digital twin application and manufacturing,facilitating the design of various products.We present a novel CAD generation method,an agent that constructs the CAD sequences containing the sketch-and-extrude modelling operations efficiently and with high quality.Starting from the sketch and extrusion operation sequences,we utilise the transformer encoder to encode them into different disentangled codebooks to represent their distribution properties while considering their correlations.Then,a combination of auto-regressive and non-autoregressive samplers is trained to sample the code for CAD sequence con-struction.Extensive experiments demonstrate that our model generates diverse and high-quality CAD models.We also show some cases of real digital twin applications and indicate that our generated model can be used as the data source for the digital twin platform,exhibiting designers'potential. 展开更多
关键词 CAD sequence construction code sample computer‐aided design digital twins hierarchical code learning
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DESIGN AND PERFORMANCE OF SYMBOL/SEQUENCE TCM FOR DS/SSMA SYSTEM OVER MOBILE RADIO CHANNEL
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作者 仰枫帆 毕光国 许宗泽 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 1999年第1期26-32,共7页
A novel kind of multidimension symbol/sequence trellis coded modulation (TCM) based on TCM of lower coding rate has been constructed. The redundancy of this new kind of TCM is provided not only by the modulated symbo... A novel kind of multidimension symbol/sequence trellis coded modulation (TCM) based on TCM of lower coding rate has been constructed. The redundancy of this new kind of TCM is provided not only by the modulated symbol sequence but also by the PN sequences for spreading spectrum as well. The performance of direct sequence spread spectrum multiple access (DS/SSMA) system with this symbol/sequence TCM over flat Rayleigh fading channel has been investigated by theoretical analysis and numerical simulation. The results obtained in this research demonstrate the performance improvements of this system in comparison with that of the DS/SSMA system with conventional TCM under the same conditions. 展开更多
关键词 TRELLIS coded modulation direct sequence spread spectrun multiple access RAYLEIGH fading channel MAXIMAL LIKELIHOOD decaling probability of bit error rate
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Auto-selection order of Markov chain for background sequences with chi-square test
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作者 谢雪英 孙啸 陆祖宏 《Journal of Southeast University(English Edition)》 EI CAS 2003年第4期311-316,共6页
Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences. Based on the chi square statistic test, some explanations about why to choose higher ... Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences. Based on the chi square statistic test, some explanations about why to choose higher order Markov chain model and how to automatically select the proper order are given in this paper. The chi square test is first run on synthetic data sets to show that it can efficiently find the proper order of Markov chain. Using chi square test, distinct higher order context dependences inherent in ten sets of sequences of yeast S.cerevisiae from other literature have been found. So the Markov chain with higher order would be more suitable for modeling the non coding background sequences than an independent model. 展开更多
关键词 non coding sequences regulatory elements chi square test Markov chain
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PERFECT PUNCTURED BINARY SEQUENCE PAIRS 被引量:15
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作者 JiangTing ZhaoXiaoqun HouLantian 《Journal of Electronics(China)》 2003年第4期285-288,共4页
This paper presents the definition of perfect punctured binary sequence pair and the combinatorial admissible conditions for searching the perfect punctured binary sequence pairs and proves that all of the pseudo-rand... This paper presents the definition of perfect punctured binary sequence pair and the combinatorial admissible conditions for searching the perfect punctured binary sequence pairs and proves that all of the pseudo-random binary sequences satisfy these conditions. Computer calculation verifies that the pseudo-random binary sequences with length up to N=127 can be easily turned into perfect punctured binary sequence pairs. 展开更多
关键词 Information theory Perfect sequences codeS pseudo-random binary sequence
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PERIODIC COMPLEMENTARY BINARY SEQUENCE PAIRS 被引量:16
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作者 XuChengqian ZhaoXiaoqun 《Journal of Electronics(China)》 2002年第2期152-159,共8页
A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the proper... A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the properties and existing conditions of PCSP and the recursive constructions for PCSP are given. 展开更多
关键词 Coding theory Periodic complementary binary sequence pairs Difference family pairs Autocorrelation function Block design
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RESEARCH ON PERFECT DYADIC BINARY SEQUENCE PAIR 被引量:2
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作者 Mao Fei Jiang Ting Zhao Chenglin Zhou Zheng 《Journal of Electronics(China)》 2006年第3期361-364,共4页
In this paper, the perfect dyadic binary sequence pair with one-value dyadic correlation functions is presented. That is, the perfect dyadic binary sequence pair is a perfect discrete signal, for its dyadic relative f... In this paper, the perfect dyadic binary sequence pair with one-value dyadic correlation functions is presented. That is, the perfect dyadic binary sequence pair is a perfect discrete signal, for its dyadic relative function is δ-function. The transformation features and some existing admissibility conditions of perfect dyadic binary sequence pair are discussed, and the properties for this kind of code in Walsh transformation spectrum and weight spectrum are also analyzed. From above, It is found that the perfect dyadic binary sequence pair can easily differentiate from its dyadic shifting. So these good signals can used in engineering as synchronization code, multi-user code and so on. 展开更多
关键词 code theory CORRELATION DYADIC sequence pair
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A reduced computational load protein coding predictor using equivalent amino acid sequence of DNA string with period-3 based time and frequency domain analysis 被引量:1
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作者 Jayakishan K. Meher Gananath N. Dash +1 位作者 Pramod Kumar Meher Mukesh Kumar Raval 《American Journal of Molecular Biology》 2011年第2期79-86,共8页
Development of efficient gene prediction algorithms is one of the fundamental efforts in gene prediction study in the area of genomics. In genomic signal processing the basic step of the identification of protein codi... Development of efficient gene prediction algorithms is one of the fundamental efforts in gene prediction study in the area of genomics. In genomic signal processing the basic step of the identification of protein coding regions in DNA sequences is based on the period-3 property exhibited by nucleotides in exons. Several approaches based on signal processing tools and numerical representations have been applied to solve this problem, trying to achieve more accurate predictions. This paper presents a new indicator sequence based on amino acid sequence, called as aminoacid indicator sequence, derived from DNA string that uses the existing signal processing based time-domain and frequency domain methods to predict these regions within the billions long DNA sequence of eukaryotic cells which reduces the computational load by one-third. It is known that each triplet of bases, called as codon, instructs the cell machinery to synthesize an amino acid. The codon sequence therefore uniquely identifies an amino acid sequence which defines a protein. Thus the protein coding region is attributed by the codons in amino acid sequence. This property is used for detection of period-3 regions using amino acid sequence. Physico-chemical properties of amino acids are used for numerical representation. Various accuracy measures such as exonic peaks, discriminating factor, sensitivity, specificity, miss rate, wrong rate and approximate correlation are used to demonstrate the efficacy of the proposed predictor. The proposed method is validated on various organisms using the standard data-set HMR195, Burset and Guigo and KEGG. The simulation result shows that the proposed method is an effective approach for protein coding prediction. 展开更多
关键词 GENOMICS Bioinformatics CODON Coding region Amino Acid sequence Fourier Transform Antinotch Filter Periodicity-3 Indicator sequence
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Evolutionary Computation for Realizing Distillation Separation Sequence Optimization Synthesis 被引量:2
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作者 Dong Hongguang Qin Limin Wang Kefeng Yao Pingjing 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS 2005年第4期52-59,共8页
Evolutionary algorithm is applied for distillation separation sequence optimization synthesis problems with combination explosion. The binary tree data structure is used to describe the distillation separation sequenc... Evolutionary algorithm is applied for distillation separation sequence optimization synthesis problems with combination explosion. The binary tree data structure is used to describe the distillation separation sequence, and it is directly applied as the coding method. Genetic operators, which ensure to prohibit illegal filial generations completely, are designed by using the method of graph theory. The crossover operator based on a single parent or two parents is designed successfully. The example shows that the average ratio of search space from evolutionary algorithm with two-parent genetic operation is lower, whereas the rate of successful minimizations from evolutionary algorithm with single parent genetic operation is higher. 展开更多
关键词 evolutionary algorithm coding method based on the binary tree crossover operator mutation operator distillation separation sequence optimization synthesis
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QUASI-SYNCHRONOUS MULTICARRIER DS-CDMA USING Z-COMPLEMENTARY SEQUENCES 被引量:1
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作者 Tu Yifeng Fan Pingzhi +1 位作者 Yuan Weina Hao Li 《Journal of Electronics(China)》 2009年第4期487-491,共5页
In this paper, a multicarrier DS-CDMA system which employs Z-Complementary Se- quences (ZCS) as spreading code is investigated. The new system can not only eliminate multipath interference and Multiple Access Interfer... In this paper, a multicarrier DS-CDMA system which employs Z-Complementary Se- quences (ZCS) as spreading code is investigated. The new system can not only eliminate multipath interference and Multiple Access Interference (MAI), but also support flexible number of users com- pared with system using Orthogonal Complementary (OC) codes. Multicarrier DS-CDMA using OC codes can be regarded as a special case of our proposed system. Zero Correlation Zone (ZCZ) of ZCS can be flexibly adjusted to meet the requirements on the user number and maximum multipath and in- ter-user delay, in this way, more users can be supported without losing interference-free property. The effectiveness of the proposed system is validated through theoretical analysis and simulation results. 展开更多
关键词 Orthogonal Complementary (OC) codes Multicarrier DS-CDMA Z-Complemen-tary sequences (ZCS) Zero Correlation Zone (ZCZ)
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Variant Map System to Simulate Complex Properties of DNA Interactions Using Binary Sequences 被引量:1
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作者 Jeffrey Zheng Weiqiong Zhang +2 位作者 Jin Luo Wei Zhou Ruoyu Shen 《Advances in Pure Mathematics》 2013年第7期5-24,共20页
Stream cipher, DNA cryptography and DNA analysis are the most important R&D fields in both Cryptography and Bioinformatics. HC-256 is an emerged scheme as the new generation of stream ciphers for advanced network ... Stream cipher, DNA cryptography and DNA analysis are the most important R&D fields in both Cryptography and Bioinformatics. HC-256 is an emerged scheme as the new generation of stream ciphers for advanced network security. From a random sequencing viewpoint, both sequences of HC-256 and real DNA data may have intrinsic pseudo-random properties respectively. In a recent decade, many DNA sequencing projects are developed on cells, plants and animals over the world into huge DNA databases. Researchers notice that mammalian genomes encode thousands of large noncoding RNAs (lncRNAs), interact with chromatin regulatory complexes, and are thought to play a role in localizing these complexes to target loci across the genome. It is a challenge target using higher dimensional visualization tools to organize various complex interactive properties as visual maps. The Variant Map System (VMS) as an emerging scheme is systematically proposed in this paper to apply multiple maps that used four Meta symbols as same as DNA or RNA representations. System architecture of key components and core mechanism on the VMS are described. Key modules, equations and their I/O parameters are discussed. Applying the VM System, two sets of real DNA sequences from both sample human (noncoding DNA) and corn (coding DNA) genomes are collected in comparison with pseudo DNA sequences generated by HC-256 to show their intrinsic properties in higher levels of similar relationships among relevant DNA sequences on 2D maps. Sample 2D maps are listed and their characteristics are illustrated under controllable environment. Visual results are briefly analyzed to explore their intrinsic properties on selected genome sequences. 展开更多
关键词 pseudo-random Number Generator STREAM CIPHER HC-256 Binary to DNA Pseudo DNA sequence Large Noncoding DNA Analysis 2D MAP Visual Distribution VARIANT MAP System
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On the Angular Distribution of the Representative Points of Bases of Human Protein Coding Sequences
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作者 Zhou Guoxiang Wang Aikun He Wenchen(Mathematics and Physics Department,Hebei University of Technology, 300130, Tianjin, China) 《河北工业大学学报》 CAS 1997年第A01期1-4,共4页
A novel diagrammtic method is proposed to show the angular distribution of bases of human protein sequences. Using this method, the distribution sphere[1-4] is divided into four regions with same volume. The picture i... A novel diagrammtic method is proposed to show the angular distribution of bases of human protein sequences. Using this method, the distribution sphere[1-4] is divided into four regions with same volume. The picture is clearer and more intuitive than that in [1] .A rule on the angular distribution of the representative points of bases of protein sequences is given. Besides, in 300 representative pointS of human protein sequence samples we find that there are three (not only one) points outside the sphere. 展开更多
关键词 ANGULAR DISTRIBUTION REPRESENTATIVE point of BASES of protein CODING sequence/ DISTRIBUTION SPHERE
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BIT-CORRELATION MATCHING FUNCTION FOR IMAGE SEQUENCE CODING
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作者 Chang Yilin Li Bingbing Sun Xianpu Li Feipeng(Xidian University, Xi’an 710071) 《Journal of Electronics(China)》 1996年第2期134-139,共6页
This paper proposes a new block matching criterion called the bit-correlation matching function for image sequence coding. When using the identical fast searching algorithm, the bit-correlation matching function not o... This paper proposes a new block matching criterion called the bit-correlation matching function for image sequence coding. When using the identical fast searching algorithm, the bit-correlation matching function not only results in nearly the same accuracy in displacement estimation as the mean square error function, but also makes the algorithm low in computation complexity and easy to parallel implementation, thus reducing the coding time of image sequence efficiently. 展开更多
关键词 Image sequence CODING DISPLACEMENT estimation Matching CRITERION
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