1 Preparation of manuscripts The manuscript should be prepared with a major word processing program and the file also submitted as a PDF(to clearly indicate all fonts).Please provide the author’s affiliation(address ...1 Preparation of manuscripts The manuscript should be prepared with a major word processing program and the file also submitted as a PDF(to clearly indicate all fonts).Please provide the author’s affiliation(address and email),an abstract of 150–300 words presenting the main arguments of the paper,4–8 keywords,high-resolution figures(with permissions),acknowledgments and references.“Documentation II:Author-Date References”in The Chicago Manual of Style and a back issue of the journal can be used as guides to prepare the manuscript.展开更多
Control of the fed-batch ethanol fermentation processes to produce maximum product ethanol is one of the key issues in the bioreactor system.However,ethanol fermentation processes exhibit complex behavior and nonlinea...Control of the fed-batch ethanol fermentation processes to produce maximum product ethanol is one of the key issues in the bioreactor system.However,ethanol fermentation processes exhibit complex behavior and nonlinear dynamics with respect to the cell mass,substrate,feed-rate,etc.An improved dual heuristic programming algorithm based on the least squares temporal difference with gradient correction(LSTDC) algorithm(LSTDC-DHP) is proposed to solve the learning control problem of a fed-batch ethanol fermentation process.As a new algorithm of adaptive critic designs,LSTDC-DHP is used to realize online learning control of chemical dynamical plants,where LSTDC is commonly employed to approximate the value functions.Application of the LSTDC-DHP algorithm to ethanol fermentation process can realize efficient online learning control in continuous spaces.Simulation results demonstrate the effectiveness of LSTDC-DHP,and show that LSTDC-DHP can obtain the near-optimal feed rate trajectory faster than other-based algorithms.展开更多
Rectisol process is more efficient in comparison with other physical or chemical absorption methods for gas purification. To implement a real time simulation of Rectisol process, thermodynamic model and simulation str...Rectisol process is more efficient in comparison with other physical or chemical absorption methods for gas purification. To implement a real time simulation of Rectisol process, thermodynamic model and simulation strategy are needed. In this paper, a method of modified statistical associated fluid theory with perturbation theory is used to predict thermodynamic behavior of process. As Rectisol process is a highly heat-integrated process with many loops, a method of equation oriented strategy, sequential quadratic programming, is used as the solver and the process converges perfectly. Then analyses are conducted with this simulator.展开更多
In this paper, a fabrication scheduling problem concerning the production of components at a single manufacturing facility was studied, in which the manufactured components are subsequently assembled into a finite num...In this paper, a fabrication scheduling problem concerning the production of components at a single manufacturing facility was studied, in which the manufactured components are subsequently assembled into a finite number of end products. Each product was assumed to comprise a common component to all jobs and a unique component to itself. Common operations were processed in batches and each batch required a setup time. A product is completed when both its two operations have been processed and are available. The optimality criterion considered was the minimization of weighted flow time. For this scheduling problem, the optimal schedules were described in a weignted shortest processing time first （WSPT） order and two algorithms were constructed corresponding to the batch availability and item availability, respectively.展开更多
This paper aims to design punching die of the stator and rotor. By analyzing and comparing, we determine the better processing program. Not only to ensure the precision and dimensional requirements, but also to improv...This paper aims to design punching die of the stator and rotor. By analyzing and comparing, we determine the better processing program. Not only to ensure the precision and dimensional requirements, but also to improve efficiency. Through detailed analysis of the process, this paper determines the structure of two composite molds. The dimensions of its convex and concave die edge size and other parts are calculated and checked. Finally this paper completes the design of two molds.展开更多
This study presents a parallel version of the string matching algorithms research tool(SMART)library,implemented on NVIDIA’s compute unified device architecture(CUDA)platform,and uses general-purpose computing on gra...This study presents a parallel version of the string matching algorithms research tool(SMART)library,implemented on NVIDIA’s compute unified device architecture(CUDA)platform,and uses general-purpose computing on graphics processing unit(GPGPU)programming concepts to enhance performance and gain insight into the parallel versions of these algorithms.We have developed the CUDA-enhanced SMART(CUSMART)library,which incorporates parallelized iterations of 64 string matching algorithms,leveraging the CUDA application programming interface.The performance of these algorithms has been assessed across various scenarios to ensure a comprehensive and impartial comparison,allowing for the identification of their strengths and weaknesses in specific application contexts.We have explored and established optimization techniques to gauge their influence on the performance of these algorithms.The results of this study highlight the potential of GPGPU computing in string matching applications through the scalability of algorithms,suggesting significant performance improvements.Furthermore,we have identified the best and worst performing algorithms in various scenarios.展开更多
A prototype expert system for generating image processing programs using the subroutine pack- age SPIDER is described in this paper.Based on an interactive dialog,the system can generate a complete application program...A prototype expert system for generating image processing programs using the subroutine pack- age SPIDER is described in this paper.Based on an interactive dialog,the system can generate a complete application program using SPIDER routines.展开更多
Alias – Wavefront OBJ meshes are a common text file type for transferring 3D mesh data between applications made by different vendors.However, as the mesh complexity gets higher and denser, the files become larger an...Alias – Wavefront OBJ meshes are a common text file type for transferring 3D mesh data between applications made by different vendors.However, as the mesh complexity gets higher and denser, the files become larger and slower to import.This paper explores the use of GPUs to accelerate the importing and parsing of OBJ files by studying file read-time, runtime, and load resistance. We propose a new method of reading and parsing that circumvents GPU architecture limitations and improves performance, seeing the new GPU method outperforms CPU methods with a 6×– 8× speedup. When running on a heavily loaded system, the new method only received an 80% performance hit, compared to the160% that the CPU methods received. The loaded GPU speedup compared to unloaded CPU methods was3.5×, and, when compared to loaded CPU methods,8×. These results demonstrate that the time is right for further research into the use of data-parallel GPU acceleration beyond that of computer graphics and high performance computing.展开更多
For this special section on software systems special section, discuss important issues that will shape several research leaders in software systems, as vip editors for this this field＇s future directions. The essa...For this special section on software systems special section, discuss important issues that will shape several research leaders in software systems, as vip editors for this this field＇s future directions. The essays included in this roundtable article cover research opportunities and challenges for emerging software systems such as data processing programs （Xiangyu Zhang） and online services （Dongmei Zhang）, with new directions of technologies such as unifications in software testing （Yves Le Traon）, data-driven and evidence-based software engineering （Qing Wang）, and dynamic analysis of multiple traces （Lu Zhang）. Tao Xie, Leading Editor of Special Section on Softwaare Svstem.展开更多
Radiotherapy exerts its effects on tumor cells directly by damaging their DNA and consequently activating a programmed cell death process(apoptosis)and indirectly by stimulating an immune response towards tumor antige...Radiotherapy exerts its effects on tumor cells directly by damaging their DNA and consequently activating a programmed cell death process(apoptosis)and indirectly by stimulating an immune response towards tumor antigens.Tumor cells are known to activate several mechanisms to preserve their survival and limit the host response,including resistance to apoptosis and immune evasion.Recently,Han et al.1 published that to limit the induction of the host immune response,tumor cells can exploit the intrinsic apoptosis program rather than block it,an apparent paradox.When exposed to the caspase inhibitor emricasan,which blocks this immune-evasion mechanism,tumor cells“adopt”countermeasures by upregulating the expression of PD-L1,which negatively controls immune responses.To eliminate this additional tumor adaptive reaction and protect the animals from tumor growth,the authors used a combination of radiation,caspase inhibition,and immune checkpoint inhibitor(anti-PD-L1 antibody)treatment.展开更多
文摘1 Preparation of manuscripts The manuscript should be prepared with a major word processing program and the file also submitted as a PDF(to clearly indicate all fonts).Please provide the author’s affiliation(address and email),an abstract of 150–300 words presenting the main arguments of the paper,4–8 keywords,high-resolution figures(with permissions),acknowledgments and references.“Documentation II:Author-Date References”in The Chicago Manual of Style and a back issue of the journal can be used as guides to prepare the manuscript.
基金Supported by the National Natural Science Foundation of China(61573052)
文摘Control of the fed-batch ethanol fermentation processes to produce maximum product ethanol is one of the key issues in the bioreactor system.However,ethanol fermentation processes exhibit complex behavior and nonlinear dynamics with respect to the cell mass,substrate,feed-rate,etc.An improved dual heuristic programming algorithm based on the least squares temporal difference with gradient correction(LSTDC) algorithm(LSTDC-DHP) is proposed to solve the learning control problem of a fed-batch ethanol fermentation process.As a new algorithm of adaptive critic designs,LSTDC-DHP is used to realize online learning control of chemical dynamical plants,where LSTDC is commonly employed to approximate the value functions.Application of the LSTDC-DHP algorithm to ethanol fermentation process can realize efficient online learning control in continuous spaces.Simulation results demonstrate the effectiveness of LSTDC-DHP,and show that LSTDC-DHP can obtain the near-optimal feed rate trajectory faster than other-based algorithms.
基金Supported by the National Basic Research Program of China(2013CB733600)
文摘Rectisol process is more efficient in comparison with other physical or chemical absorption methods for gas purification. To implement a real time simulation of Rectisol process, thermodynamic model and simulation strategy are needed. In this paper, a method of modified statistical associated fluid theory with perturbation theory is used to predict thermodynamic behavior of process. As Rectisol process is a highly heat-integrated process with many loops, a method of equation oriented strategy, sequential quadratic programming, is used as the solver and the process converges perfectly. Then analyses are conducted with this simulator.
文摘In this paper, a fabrication scheduling problem concerning the production of components at a single manufacturing facility was studied, in which the manufactured components are subsequently assembled into a finite number of end products. Each product was assumed to comprise a common component to all jobs and a unique component to itself. Common operations were processed in batches and each batch required a setup time. A product is completed when both its two operations have been processed and are available. The optimality criterion considered was the minimization of weighted flow time. For this scheduling problem, the optimal schedules were described in a weignted shortest processing time first （WSPT） order and two algorithms were constructed corresponding to the batch availability and item availability, respectively.
基金Supported by Science and Technology Researcher Project of Anhui Province(15czz02030)International Scientific and Technological Cooperation Projects of China(No.2013DFB70350)
文摘This paper aims to design punching die of the stator and rotor. By analyzing and comparing, we determine the better processing program. Not only to ensure the precision and dimensional requirements, but also to improve efficiency. Through detailed analysis of the process, this paper determines the structure of two composite molds. The dimensions of its convex and concave die edge size and other parts are calculated and checked. Finally this paper completes the design of two molds.
基金Project supported by the Scientific and Technological Research Council of Türkiye(No.117E142)Open access funding provided by the Scientific and Technological Research Council of Türkiye(TÜBİTAK)。
文摘This study presents a parallel version of the string matching algorithms research tool(SMART)library,implemented on NVIDIA’s compute unified device architecture(CUDA)platform,and uses general-purpose computing on graphics processing unit(GPGPU)programming concepts to enhance performance and gain insight into the parallel versions of these algorithms.We have developed the CUDA-enhanced SMART(CUSMART)library,which incorporates parallelized iterations of 64 string matching algorithms,leveraging the CUDA application programming interface.The performance of these algorithms has been assessed across various scenarios to ensure a comprehensive and impartial comparison,allowing for the identification of their strengths and weaknesses in specific application contexts.We have explored and established optimization techniques to gauge their influence on the performance of these algorithms.The results of this study highlight the potential of GPGPU computing in string matching applications through the scalability of algorithms,suggesting significant performance improvements.Furthermore,we have identified the best and worst performing algorithms in various scenarios.
文摘A prototype expert system for generating image processing programs using the subroutine pack- age SPIDER is described in this paper.Based on an interactive dialog,the system can generate a complete application program using SPIDER routines.
文摘Alias – Wavefront OBJ meshes are a common text file type for transferring 3D mesh data between applications made by different vendors.However, as the mesh complexity gets higher and denser, the files become larger and slower to import.This paper explores the use of GPUs to accelerate the importing and parsing of OBJ files by studying file read-time, runtime, and load resistance. We propose a new method of reading and parsing that circumvents GPU architecture limitations and improves performance, seeing the new GPU method outperforms CPU methods with a 6×– 8× speedup. When running on a heavily loaded system, the new method only received an 80% performance hit, compared to the160% that the CPU methods received. The loaded GPU speedup compared to unloaded CPU methods was3.5×, and, when compared to loaded CPU methods,8×. These results demonstrate that the time is right for further research into the use of data-parallel GPU acceleration beyond that of computer graphics and high performance computing.
文摘For this special section on software systems special section, discuss important issues that will shape several research leaders in software systems, as vip editors for this this field＇s future directions. The essays included in this roundtable article cover research opportunities and challenges for emerging software systems such as data processing programs （Xiangyu Zhang） and online services （Dongmei Zhang）, with new directions of technologies such as unifications in software testing （Yves Le Traon）, data-driven and evidence-based software engineering （Qing Wang）, and dynamic analysis of multiple traces （Lu Zhang）. Tao Xie, Leading Editor of Special Section on Softwaare Svstem.
文摘Radiotherapy exerts its effects on tumor cells directly by damaging their DNA and consequently activating a programmed cell death process(apoptosis)and indirectly by stimulating an immune response towards tumor antigens.Tumor cells are known to activate several mechanisms to preserve their survival and limit the host response,including resistance to apoptosis and immune evasion.Recently,Han et al.1 published that to limit the induction of the host immune response,tumor cells can exploit the intrinsic apoptosis program rather than block it,an apparent paradox.When exposed to the caspase inhibitor emricasan,which blocks this immune-evasion mechanism,tumor cells“adopt”countermeasures by upregulating the expression of PD-L1,which negatively controls immune responses.To eliminate this additional tumor adaptive reaction and protect the animals from tumor growth,the authors used a combination of radiation,caspase inhibition,and immune checkpoint inhibitor(anti-PD-L1 antibody)treatment.
