Purpose:This study examined potential differences in strength,muscle morphology,and motor unit(MU)behavior of the abductor digiti minimi(ADM)between normal-fat(NF)and over-fat(OF)males.Methods:Dual-energy X-ray absorp...Purpose:This study examined potential differences in strength,muscle morphology,and motor unit(MU)behavior of the abductor digiti minimi(ADM)between normal-fat(NF)and over-fat(OF)males.Methods:Dual-energy X-ray absorptiometry assessed percent body fat(%BF).Ultrasonography determined muscle cross-sectional area(CSA),echo intensity(EI),and subcutaneous fat(s FAT).MU behavior was assessed during isometric muscle actions at 50%of maximal voluntary contraction(MVC)by analyzing the y-intercepts and slopes for the MU action potential amplitude(MUAPAMP)vs.recruitment threshold(RT)relationships,the A and B terms for the mean firing rate(MFR)vs.RT relationships,and normalized electromyographic amplitude(N-EMGRMS).MU firing times and waveforms were validated with reconstruct-and-test and spike trigger average procedures.Results:%BF was greater for OF(25.70%±5.40%)than NF(16.50%±2.20%;p<0.001).MVC was greater for NF(27.13±7.16)N than OF([19.89±4.96]N;p=0.014).CSA was greater for NF(2.48±0.39)cm^(2)than OF([1.95±0.47]cm^(2);p=0.011).The y-intercepts for the MUAPAMPvs.RT relationships were greater for NF(0.283±0.254)m V than OF([-0.221±0.659]m V;p=0.004).The B terms for the MFR vs.RT relationships were greater for NF(-0.024±0.003)pps/%MVC than OF([-0.031±0.009]pps/%MVC;p=0.038).N-EMGRMSwas similar between groups(p=0.463).Conclusion:Maximal strength,muscle size,and MU recruitment and firing rate patterns for a non-weight bearing muscle differed between normal-fat and over-fat males.展开更多
Apparel exports China:The decline in exports widened from January to September(-2.4%,compared to-0.2%in January-June).Exports to the EU increased(+5.9%),though the growth rate moderated.Exports to the US saw a larger ...Apparel exports China:The decline in exports widened from January to September(-2.4%,compared to-0.2%in January-June).Exports to the EU increased(+5.9%),though the growth rate moderated.Exports to the US saw a larger contraction(January-June:-1.6%,January-September:-8.2%).While exports to ASEAN countries still fell by over 10%(-17.7%),shipments to the Philippines(+6.9%),Indonesia(+19.0%),and Cambodia(+64.9%)demonstrated stronger growth performance within the year.Regarding tariffs,on October 30,China and the US agreed to lower the rates on goods subject to additional duties(effectively reducing the average tariff rate on Chinese imports to the US from about 57%to approximately 47%,though this remains significantly higher than the 19.5%overall average rate applied to other countries).展开更多
As a public basic course and the core general course of undergraduate education,moral education(ME)in College English is imperative.It is necessary to design specific teaching programs flexibly and creatively on the b...As a public basic course and the core general course of undergraduate education,moral education(ME)in College English is imperative.It is necessary to design specific teaching programs flexibly and creatively on the basis of fully understanding the ideas,objectives and tasks,basic principles and implementation methods of ME.This paper tries integrating literature reading into unit topic teaching as a new approach to ME in College English.The specific pathways of integration include:expansion of literary reading content,diversified teaching of literary reading,diversified media of literary reading,and diversified assessment system of literary quality.The integration of literature reading and unit topic teaching is conducive to the realization of the teaching goal of cultivating students’language ability,humanistic quality,and correct values.展开更多
Slope units are divided according to the real topography and have clear geological characteristics,making them ideal units for evaluating the susceptibility to geological disasters.Based on the results of automaticall...Slope units are divided according to the real topography and have clear geological characteristics,making them ideal units for evaluating the susceptibility to geological disasters.Based on the results of automatically and manually corrected hydrological slope unit division,the Longhua District,Shenzhen City,Guangdong Province,was selected as the study area.A total of 15 influencing factors,namely Fluctuation,slope,slope aspect,curvature,topographic witness index(TWI),stream power index(SPI),topographic roughness index(TRI),annual average rainfall,distance to water system,engineering rock group,distance to fault,land use,normalized difference vegetation index(NDVI),nighttime light,and distance to road,were selected as evaluation indicators.The information volume model(IV)and random points were used to select non-geological disaster units,and then the random forest model(RF)was used to evaluate the susceptibility to geological disasters.The automatic slope unit and the hydrological slope unit were compared and analyzed in the random forest and information volume random forest models.The results show that the area under the curve(AUC)values of the automatic slope unit evaluation results are 0.931 for the IV-RF model and 0.716 for the RF model,which are 0.6%(IV-RF model)and 1.9%(RF model)higher than those for the hydrological slope unit.Based on a comparison of the evaluation methods based on the two types of slope units,the hydrological slope unit evaluation method based on manual correction is highly subjective,is complicated to operate,and has a low evaluation accuracy,whereas the evaluation method based on automatic slope unit division is efficient and accurate,is suitable for large-scale efficient geological disaster evaluation,and can better deal with the problem of geological disaster susceptibility evaluation.展开更多
1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconn...1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconnected social,economic,and environmental targets.展开更多
Modular truss space deployable antennas are key for future large aperture,high precision antennas,already proven in various in-orbit applications globally.This paper introduces a design method for a tetrahedral basic ...Modular truss space deployable antennas are key for future large aperture,high precision antennas,already proven in various in-orbit applications globally.This paper introduces a design method for a tetrahedral basic unit mechanism with dual height positioning nodes.A parametric model is established,and its DOF are analyzed to confirm the mechanism's validity.The new tetrahedral basic unit mechanism constructed by this method is a single DOF mechanism and can locate different parabolic node heights.In order to further adapt to the parabolic and large aperture requirements of the deployable antenna of the truss,a combination unit and modular unit mechanism are developed based on this tetrahedral unit.The DOF and deployment characteristics of the modular unit mechanism are analyzed and validated through simulations.Various networking methods for the modular units are proposed,followed by a comprehensive performance comparison of different modular truss deployable antenna mechanisms.A prototype model of the modular unit mechanism is also developed,with deployment experiments demonstrating the mechanism's simplicity,low DOF,and large deployment ratio.The findings of this study provide a theoretical and technical basis for the future design and development of truss deployable antenna mechanisms.展开更多
Objective:To identify the root causes of typical adverse drug events through the lens of patient experiences proposing novel strategies to mitigate preventable harm.Methods:A qualitative case study leveraging in-depth...Objective:To identify the root causes of typical adverse drug events through the lens of patient experiences proposing novel strategies to mitigate preventable harm.Methods:A qualitative case study leveraging in-depth interviews with patients and families,anchored by Interactive Patient Par ticipation Theory,to analyze 4 high-severity adverse drug events(ADE)cases.Cases were purposively sampled from 8 communities in China's National Adverse Event Monitor Center(2018-2023).Semi-structured interviews explored patient perspectives,with data analyzed via thematic coding and triangulation against clinical records.Results:Five interconnected themes emerged:(1)erosion of trust,(2)communication breakdowns,(3)information asymmetry,(4)environmental inadequacies,and(5)technological alienation.Notably,75% of participants had≤high school education,and 50% used≥7 medications daily,compounding ADE risks.Conclusions:We considered elements mentioned by theory,exploring trust,communication,information,and suppor t as the root causes.In addition,we added“adaptability to new technology”as an impor tant and necessary component.It is impor tant and necessary to analyze typical adverse drug events from the perspectives of patients.展开更多
BACKGROUND Living donor kidney transplantation is the optimal method of long-term renal replacement therapy.Minimally invasive donor nephrectomy techniques,such as robot-assisted(RALDN)and hand-assisted(HALDN)laparosc...BACKGROUND Living donor kidney transplantation is the optimal method of long-term renal replacement therapy.Minimally invasive donor nephrectomy techniques,such as robot-assisted(RALDN)and hand-assisted(HALDN)laparoscopic procedures,are well-established in high-income countries and are being increasingly adopted worldwide.Nevertheless,no studies have reported surgical outcomes of RALDN donor nephrectomy from a United Kingdom center to date.AIM To compare surgical outcomes between RALDN and HALDN laparoscopic donor nephrectomy in a United Kingdom high-volume living kidney donor transplant program.METHODS A case-control matching analysis was performed based on the following parameters:Sex,age,body mass index,procedure laterality,number of renal arteries,and previous abdominal surgeries.Key surgical outcomes,including primary warm ischemia time,operative duration,and post-operative recovery,were evaluated.RESULTS In this cohort of 140 living donors(70 RALDN vs 70 HALDN),donor and recipient outcomes were equivalent across key metrics:Pain scores,overall complication rates,readmissions,reoperations,and creatinine levels at 30 days and 1 year.Recipient long-term renal function did not differ between groups.Operative time for RALDN decreased significantly over the study period,indicating progressive improvement along the learning curve.Although RALDN was associated with a modestly longer mean warm ischaemia time(3.53 minutes vs 2.76 minutes,P<0.001)and extended hospital stay(4.21 days vs 3.17 days,P<0.001),these did not translate into any disadvantage in clinical outcomes.CONCLUSION In this first United Kingdom comparative cohort,RALDN demonstrated excellent safety and efficacy,even in the early phase of our programme,matching the outcomes of the well-established,gold-standard HALDN approach.Moreover,the pronounced learning-curve trajectory suggests considerable potential for further improvements in robotic surgical outcomes as the programme matures.展开更多
The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. Th...The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. The brain is made up of a complex network of different cell types that work in tandem to maintain systemic homeostasis.展开更多
Despite advances in current anti-cancer therapies,challenges such as drug resistance,toxicity,and tumor heterogeneity persist.The limitations of traditional single-target drugs and simple combination therapies are bec...Despite advances in current anti-cancer therapies,challenges such as drug resistance,toxicity,and tumor heterogeneity persist.The limitations of traditional single-target drugs and simple combination therapies are becoming increasingly apparent1.To address these issues,a novel treatment strategy,the artificially intelligent synergistic engineered drug(AISED)paradigm,merits further exploration.This paradigm is based on the systematic engineered integration of multiple active ingredients into a unified single entity through artificial intelligence(AI).This strategy is aimed at developing new anti-cancer drug designs involving multiple ingredients,multiple molecular targets,and multiple biological effects,for multiple cancer types,thereby providing a novel theoretical paradigm for overcoming existing treatment bottlenecks.展开更多
本研究基于单元整体教学视角,旨在探索初中英语“教―学―评”一致性课堂构建策略。针对当前初中英语教学中的目标碎片化、内容割裂、评价模糊、闭环断裂等困境,文章以逆向设计与结构主义为理论支撑,以核心素养为导向,提出“目标锚定―...本研究基于单元整体教学视角,旨在探索初中英语“教―学―评”一致性课堂构建策略。针对当前初中英语教学中的目标碎片化、内容割裂、评价模糊、闭环断裂等困境,文章以逆向设计与结构主义为理论支撑,以核心素养为导向,提出“目标锚定―内容整合―标准研制―实践实施”四步策略,以重构层级化、主题化的单元目标体系。同时,本研究以“人教版”七年级上册Unit 3 My School为例进行实证检验,结果显示,上述策略能有效提升学生的语言、文化、思维、学习能力,实现核心素养的课堂转化,为教师提供可操作的单元整体教学设计指南。展开更多
Regular expression matching is playing an important role in deep inspection. The rapid development of SDN and NFV makes the network more dynamic, bringing serious challenges to traditional deep inspection matching eng...Regular expression matching is playing an important role in deep inspection. The rapid development of SDN and NFV makes the network more dynamic, bringing serious challenges to traditional deep inspection matching engines. However, state-of-theart matching methods often require a significant amount of pre-processing time and hence are not suitable for this fast updating scenario. In this paper, a novel matching engine called BFA is proposed to achieve high-speed regular expression matching with fast pre-processing. Experiments demonstrate that BFA obtains 5 to 20 times more update abilities compared to existing regular expression matching methods, and scales well on multi-core platforms.展开更多
In order to carry out numerical simulation using geologic structural data obtained from Landmark(seismic interpretation system), underground geological structures are abstracted into mechanical models which can reflec...In order to carry out numerical simulation using geologic structural data obtained from Landmark(seismic interpretation system), underground geological structures are abstracted into mechanical models which can reflect actual situations and facilitate their computation and analyses.Given the importance of model building, further processing methods about traditional seismic interpretation results from Landmark should be studied and the processed result can then be directly used in numerical simulation computations.Through this data conversion procedure, Landmark and FLAC(the international general stress software) are seamlessly connected.Thus, the format conversion between the two systems and the pre-and post-processing in simulation computation is realized.A practical application indicates that this method has many advantages such as simple operation, high accuracy of the element subdivision and high speed, which may definitely satisfy the actual needs of floor grid cutting.展开更多
The Low Earth Orbit(LEO)remote sensing satellite mega-constellation has the characteristics of large quantity and various types which make it have unique superiority in the realization of concurrent multiple tasks.How...The Low Earth Orbit(LEO)remote sensing satellite mega-constellation has the characteristics of large quantity and various types which make it have unique superiority in the realization of concurrent multiple tasks.However,the complexity of resource allocation is increased because of the large number of tasks and satellites.Therefore,the primary problem of implementing concurrent multiple tasks via LEO mega-constellation is to pre-process tasks and observation re-sources.To address the challenge,we propose a pre-processing algorithm for the mega-constellation based on highly Dynamic Spatio-Temporal Grids(DSTG).In the first stage,this paper describes the management model of mega-constellation and the multiple tasks.Then,the coding method of DSTG is proposed,based on which the description of complex mega-constellation observation resources is realized.In the third part,the DSTG algorithm is used to realize the processing of concurrent multiple tasks at multiple levels,such as task space attribute,time attribute and grid task importance evaluation.Finally,the simulation result of the proposed method in the case of constellation has been given to verify the effectiveness of concurrent multi-task pre-processing based on DSTG.The autonomous processing process of task decomposition and task fusion and mapping to grids,and the convenient indexing process of time window are verified.展开更多
In order to meet the demands for high transmission rates and high service quality in broadband wireless communication systems, orthogonal frequency division multiplexing （OFDM） has been adopted in some standards. Ho...In order to meet the demands for high transmission rates and high service quality in broadband wireless communication systems, orthogonal frequency division multiplexing （OFDM） has been adopted in some standards. However, the inter-block interference （IBI） and inter-carrier interference （ICI） in an OFDM system affect the performance. To mitigate IBI and ICI, some pre-processing approaches have been proposed based on full channel state information （CSI）, which improved the system performance. A pre-processing filter based on partial CSI at the transmitter is designed and investigated. The filter coefficient is given by the optimization processing, the symbol error rate （SER） is tested, and the computation complexity of the proposed scheme is analyzed. Computer simulation results show that the proposed pre-processing filter can effectively mitigate IBI and ICI and the performance can be improved. Compared with pre-processing approaches at the transmitter based on full CSI, the proposed scheme has high spectral efficiency, limited CSI feedback and low computation complexity.展开更多
The Chang＇e-3 （CE-3） mission is China＇s first exploration mission on the surface of the Moon that uses a lander and a rover. Eight instruments that form the scientific payloads have the following objectives： （1...The Chang＇e-3 （CE-3） mission is China＇s first exploration mission on the surface of the Moon that uses a lander and a rover. Eight instruments that form the scientific payloads have the following objectives： （1） investigate the morphological features and geological structures at the landing site; （2） integrated in-situ analysis of minerals and chemical compositions; （3） integrated exploration of the structure of the lunar interior; （4） exploration of the lunar-terrestrial space environment, lunar sur- face environment and acquire Moon-based ultraviolet astronomical observations. The Ground Research and Application System （GRAS） is in charge of data acquisition and pre-processing, management of the payload in orbit, and managing the data products and their applications. The Data Pre-processing Subsystem （DPS） is a part of GRAS. The task of DPS is the pre-processing of raw data from the eight instruments that are part of CE-3, including channel processing, unpacking, package sorting, calibration and correction, identification of geographical location, calculation of probe azimuth angle, probe zenith angle, solar azimuth angle, and solar zenith angle and so on, and conducting quality checks. These processes produce Level 0, Level 1 and Level 2 data. The computing platform of this subsystem is comprised of a high-performance computing cluster, including a real-time subsystem used for processing Level 0 data and a post-time subsystem for generating Level 1 and Level 2 data. This paper de- scribes the CE-3 data pre-processing method, the data pre-processing subsystem, data classification, data validity and data products that are used for scientific studies.展开更多
High-resolution ice core records covering long time spans enable reconstruction of the past climatic and environmental conditions allowing the investigation of the earth system's evolution.Preprocessing of ice cor...High-resolution ice core records covering long time spans enable reconstruction of the past climatic and environmental conditions allowing the investigation of the earth system's evolution.Preprocessing of ice cores has direct impacts on the data quality control for further analysis since the conventional ice core processing is time-consuming,produces qualitative data,leads to ice mass loss,and leads to risks of potential secondary pollution.However,over the past several decades,preprocessing of ice cores has received less attention than the improvement of ice drilling,the analytical methodology of various indices,and the researches on the climatic and environmental significance of ice core records.Therefore,this papers reviews the development of the processing for ice cores including framework,design as well as materials,analyzes the technical advantages and disadvantages of the different systems.In the past,continuous flowanalysis(CFA)has been successfully applied to process the polar ice cores.However,it is not suitable for ice cores outside polar region because of high level of particles,the memory effect between samples,and the filtration before injection.Ice core processing is a subtle and professional operation due to the fragility of the nonmetallic materials and the random distribution of particles and air bubbles in ice cores,which aggravates uncertainty in the measurements.The future developments of CFA are discussed in preprocessing,memory effect,challenge for brittle ice,coupling with real-time analysis and optimization of CFA in the field.Furthermore,non-polluting cutters with many different configurations could be designed to cut and scrape in multiple directions and to separate inner and outer portions of the core.This system also needs to be coupled with streamlined operation of packaging,coding,and stacking that can be implemented at high resolution and rate,avoiding manual intervention.At the same time,information of the longitudinal sections could be scanned andidentified,and then classified to obtain quantitative data.In addition,irregular ice volume and weight can also be obtained accurately.These improvements are recorded automatically via user-friendly interfaces.These innovations may be applied to other paleomedias with similar features and needs.展开更多
Mathematical morphology is widely applicated in digital image procesing.Vari- ary morphology construction and algorithm being developed are used in deferent digital image processing.The basic idea of mathematical morp...Mathematical morphology is widely applicated in digital image procesing.Vari- ary morphology construction and algorithm being developed are used in deferent digital image processing.The basic idea of mathematical morphology is to use construction ele- ment measure image morphology for solving understand problem.The article presented advanced cellular neural network that forms mathematical morphological cellular neural network (MMCNN) equation to be suit for mathematical morphology filter.It gave the theo- ries of MMCNN dynamic extent and stable state.It is evidenced that arrived mathematical morphology filter through steady of dynamic process in definite condition.展开更多
文摘Purpose:This study examined potential differences in strength,muscle morphology,and motor unit(MU)behavior of the abductor digiti minimi(ADM)between normal-fat(NF)and over-fat(OF)males.Methods:Dual-energy X-ray absorptiometry assessed percent body fat(%BF).Ultrasonography determined muscle cross-sectional area(CSA),echo intensity(EI),and subcutaneous fat(s FAT).MU behavior was assessed during isometric muscle actions at 50%of maximal voluntary contraction(MVC)by analyzing the y-intercepts and slopes for the MU action potential amplitude(MUAPAMP)vs.recruitment threshold(RT)relationships,the A and B terms for the mean firing rate(MFR)vs.RT relationships,and normalized electromyographic amplitude(N-EMGRMS).MU firing times and waveforms were validated with reconstruct-and-test and spike trigger average procedures.Results:%BF was greater for OF(25.70%±5.40%)than NF(16.50%±2.20%;p<0.001).MVC was greater for NF(27.13±7.16)N than OF([19.89±4.96]N;p=0.014).CSA was greater for NF(2.48±0.39)cm^(2)than OF([1.95±0.47]cm^(2);p=0.011).The y-intercepts for the MUAPAMPvs.RT relationships were greater for NF(0.283±0.254)m V than OF([-0.221±0.659]m V;p=0.004).The B terms for the MFR vs.RT relationships were greater for NF(-0.024±0.003)pps/%MVC than OF([-0.031±0.009]pps/%MVC;p=0.038).N-EMGRMSwas similar between groups(p=0.463).Conclusion:Maximal strength,muscle size,and MU recruitment and firing rate patterns for a non-weight bearing muscle differed between normal-fat and over-fat males.
文摘Apparel exports China:The decline in exports widened from January to September(-2.4%,compared to-0.2%in January-June).Exports to the EU increased(+5.9%),though the growth rate moderated.Exports to the US saw a larger contraction(January-June:-1.6%,January-September:-8.2%).While exports to ASEAN countries still fell by over 10%(-17.7%),shipments to the Philippines(+6.9%),Indonesia(+19.0%),and Cambodia(+64.9%)demonstrated stronger growth performance within the year.Regarding tariffs,on October 30,China and the US agreed to lower the rates on goods subject to additional duties(effectively reducing the average tariff rate on Chinese imports to the US from about 57%to approximately 47%,though this remains significantly higher than the 19.5%overall average rate applied to other countries).
文摘As a public basic course and the core general course of undergraduate education,moral education(ME)in College English is imperative.It is necessary to design specific teaching programs flexibly and creatively on the basis of fully understanding the ideas,objectives and tasks,basic principles and implementation methods of ME.This paper tries integrating literature reading into unit topic teaching as a new approach to ME in College English.The specific pathways of integration include:expansion of literary reading content,diversified teaching of literary reading,diversified media of literary reading,and diversified assessment system of literary quality.The integration of literature reading and unit topic teaching is conducive to the realization of the teaching goal of cultivating students’language ability,humanistic quality,and correct values.
文摘Slope units are divided according to the real topography and have clear geological characteristics,making them ideal units for evaluating the susceptibility to geological disasters.Based on the results of automatically and manually corrected hydrological slope unit division,the Longhua District,Shenzhen City,Guangdong Province,was selected as the study area.A total of 15 influencing factors,namely Fluctuation,slope,slope aspect,curvature,topographic witness index(TWI),stream power index(SPI),topographic roughness index(TRI),annual average rainfall,distance to water system,engineering rock group,distance to fault,land use,normalized difference vegetation index(NDVI),nighttime light,and distance to road,were selected as evaluation indicators.The information volume model(IV)and random points were used to select non-geological disaster units,and then the random forest model(RF)was used to evaluate the susceptibility to geological disasters.The automatic slope unit and the hydrological slope unit were compared and analyzed in the random forest and information volume random forest models.The results show that the area under the curve(AUC)values of the automatic slope unit evaluation results are 0.931 for the IV-RF model and 0.716 for the RF model,which are 0.6%(IV-RF model)and 1.9%(RF model)higher than those for the hydrological slope unit.Based on a comparison of the evaluation methods based on the two types of slope units,the hydrological slope unit evaluation method based on manual correction is highly subjective,is complicated to operate,and has a low evaluation accuracy,whereas the evaluation method based on automatic slope unit division is efficient and accurate,is suitable for large-scale efficient geological disaster evaluation,and can better deal with the problem of geological disaster susceptibility evaluation.
文摘1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconnected social,economic,and environmental targets.
基金sponsored by the National Natural Science Foundation of China(No.52075467)Hebei Province Fund Outstanding Youth Fund Project,China(No.E2024203107)。
文摘Modular truss space deployable antennas are key for future large aperture,high precision antennas,already proven in various in-orbit applications globally.This paper introduces a design method for a tetrahedral basic unit mechanism with dual height positioning nodes.A parametric model is established,and its DOF are analyzed to confirm the mechanism's validity.The new tetrahedral basic unit mechanism constructed by this method is a single DOF mechanism and can locate different parabolic node heights.In order to further adapt to the parabolic and large aperture requirements of the deployable antenna of the truss,a combination unit and modular unit mechanism are developed based on this tetrahedral unit.The DOF and deployment characteristics of the modular unit mechanism are analyzed and validated through simulations.Various networking methods for the modular units are proposed,followed by a comprehensive performance comparison of different modular truss deployable antenna mechanisms.A prototype model of the modular unit mechanism is also developed,with deployment experiments demonstrating the mechanism's simplicity,low DOF,and large deployment ratio.The findings of this study provide a theoretical and technical basis for the future design and development of truss deployable antenna mechanisms.
基金supported by the Science and Technology Fund Project of Guizhou Health Commission(gzwkj2025-163)。
文摘Objective:To identify the root causes of typical adverse drug events through the lens of patient experiences proposing novel strategies to mitigate preventable harm.Methods:A qualitative case study leveraging in-depth interviews with patients and families,anchored by Interactive Patient Par ticipation Theory,to analyze 4 high-severity adverse drug events(ADE)cases.Cases were purposively sampled from 8 communities in China's National Adverse Event Monitor Center(2018-2023).Semi-structured interviews explored patient perspectives,with data analyzed via thematic coding and triangulation against clinical records.Results:Five interconnected themes emerged:(1)erosion of trust,(2)communication breakdowns,(3)information asymmetry,(4)environmental inadequacies,and(5)technological alienation.Notably,75% of participants had≤high school education,and 50% used≥7 medications daily,compounding ADE risks.Conclusions:We considered elements mentioned by theory,exploring trust,communication,information,and suppor t as the root causes.In addition,we added“adaptability to new technology”as an impor tant and necessary component.It is impor tant and necessary to analyze typical adverse drug events from the perspectives of patients.
文摘BACKGROUND Living donor kidney transplantation is the optimal method of long-term renal replacement therapy.Minimally invasive donor nephrectomy techniques,such as robot-assisted(RALDN)and hand-assisted(HALDN)laparoscopic procedures,are well-established in high-income countries and are being increasingly adopted worldwide.Nevertheless,no studies have reported surgical outcomes of RALDN donor nephrectomy from a United Kingdom center to date.AIM To compare surgical outcomes between RALDN and HALDN laparoscopic donor nephrectomy in a United Kingdom high-volume living kidney donor transplant program.METHODS A case-control matching analysis was performed based on the following parameters:Sex,age,body mass index,procedure laterality,number of renal arteries,and previous abdominal surgeries.Key surgical outcomes,including primary warm ischemia time,operative duration,and post-operative recovery,were evaluated.RESULTS In this cohort of 140 living donors(70 RALDN vs 70 HALDN),donor and recipient outcomes were equivalent across key metrics:Pain scores,overall complication rates,readmissions,reoperations,and creatinine levels at 30 days and 1 year.Recipient long-term renal function did not differ between groups.Operative time for RALDN decreased significantly over the study period,indicating progressive improvement along the learning curve.Although RALDN was associated with a modestly longer mean warm ischaemia time(3.53 minutes vs 2.76 minutes,P<0.001)and extended hospital stay(4.21 days vs 3.17 days,P<0.001),these did not translate into any disadvantage in clinical outcomes.CONCLUSION In this first United Kingdom comparative cohort,RALDN demonstrated excellent safety and efficacy,even in the early phase of our programme,matching the outcomes of the well-established,gold-standard HALDN approach.Moreover,the pronounced learning-curve trajectory suggests considerable potential for further improvements in robotic surgical outcomes as the programme matures.
文摘The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. The brain is made up of a complex network of different cell types that work in tandem to maintain systemic homeostasis.
文摘Despite advances in current anti-cancer therapies,challenges such as drug resistance,toxicity,and tumor heterogeneity persist.The limitations of traditional single-target drugs and simple combination therapies are becoming increasingly apparent1.To address these issues,a novel treatment strategy,the artificially intelligent synergistic engineered drug(AISED)paradigm,merits further exploration.This paradigm is based on the systematic engineered integration of multiple active ingredients into a unified single entity through artificial intelligence(AI).This strategy is aimed at developing new anti-cancer drug designs involving multiple ingredients,multiple molecular targets,and multiple biological effects,for multiple cancer types,thereby providing a novel theoretical paradigm for overcoming existing treatment bottlenecks.
文摘本研究基于单元整体教学视角,旨在探索初中英语“教―学―评”一致性课堂构建策略。针对当前初中英语教学中的目标碎片化、内容割裂、评价模糊、闭环断裂等困境,文章以逆向设计与结构主义为理论支撑,以核心素养为导向,提出“目标锚定―内容整合―标准研制―实践实施”四步策略,以重构层级化、主题化的单元目标体系。同时,本研究以“人教版”七年级上册Unit 3 My School为例进行实证检验,结果显示,上述策略能有效提升学生的语言、文化、思维、学习能力,实现核心素养的课堂转化,为教师提供可操作的单元整体教学设计指南。
基金supported by the National Key Technology R&D Program of China under Grant No. 2015BAK34B00the National Key Research and Development Program of China under Grant No. 2016YFB1000102
文摘Regular expression matching is playing an important role in deep inspection. The rapid development of SDN and NFV makes the network more dynamic, bringing serious challenges to traditional deep inspection matching engines. However, state-of-theart matching methods often require a significant amount of pre-processing time and hence are not suitable for this fast updating scenario. In this paper, a novel matching engine called BFA is proposed to achieve high-speed regular expression matching with fast pre-processing. Experiments demonstrate that BFA obtains 5 to 20 times more update abilities compared to existing regular expression matching methods, and scales well on multi-core platforms.
基金Projects 50221402, 50490271 and 50025413 supported by the National Natural Science Foundation of Chinathe National Basic Research Program of China (2009CB219603, 2009 CB724601, 2006CB202209 and 2005CB221500)+1 种基金the Key Project of the Ministry of Education (306002)the Program for Changjiang Scholars and Innovative Research Teams in Universities of MOE (IRT0408)
文摘In order to carry out numerical simulation using geologic structural data obtained from Landmark(seismic interpretation system), underground geological structures are abstracted into mechanical models which can reflect actual situations and facilitate their computation and analyses.Given the importance of model building, further processing methods about traditional seismic interpretation results from Landmark should be studied and the processed result can then be directly used in numerical simulation computations.Through this data conversion procedure, Landmark and FLAC(the international general stress software) are seamlessly connected.Thus, the format conversion between the two systems and the pre-and post-processing in simulation computation is realized.A practical application indicates that this method has many advantages such as simple operation, high accuracy of the element subdivision and high speed, which may definitely satisfy the actual needs of floor grid cutting.
基金supported by the National Natural Science Foundation of China(Nos.62003115 and 11972130)the Shenzhen Science and Technology Program,China(JCYJ20220818102207015)the Heilongjiang Touyan Team Program,China。
文摘The Low Earth Orbit(LEO)remote sensing satellite mega-constellation has the characteristics of large quantity and various types which make it have unique superiority in the realization of concurrent multiple tasks.However,the complexity of resource allocation is increased because of the large number of tasks and satellites.Therefore,the primary problem of implementing concurrent multiple tasks via LEO mega-constellation is to pre-process tasks and observation re-sources.To address the challenge,we propose a pre-processing algorithm for the mega-constellation based on highly Dynamic Spatio-Temporal Grids(DSTG).In the first stage,this paper describes the management model of mega-constellation and the multiple tasks.Then,the coding method of DSTG is proposed,based on which the description of complex mega-constellation observation resources is realized.In the third part,the DSTG algorithm is used to realize the processing of concurrent multiple tasks at multiple levels,such as task space attribute,time attribute and grid task importance evaluation.Finally,the simulation result of the proposed method in the case of constellation has been given to verify the effectiveness of concurrent multi-task pre-processing based on DSTG.The autonomous processing process of task decomposition and task fusion and mapping to grids,and the convenient indexing process of time window are verified.
基金supported by the National Natural Science Foundation of China(60902045)the National High-Tech Research and Developmeent Program of China(863 Program)(2011AA01A105)
文摘In order to meet the demands for high transmission rates and high service quality in broadband wireless communication systems, orthogonal frequency division multiplexing （OFDM） has been adopted in some standards. However, the inter-block interference （IBI） and inter-carrier interference （ICI） in an OFDM system affect the performance. To mitigate IBI and ICI, some pre-processing approaches have been proposed based on full channel state information （CSI）, which improved the system performance. A pre-processing filter based on partial CSI at the transmitter is designed and investigated. The filter coefficient is given by the optimization processing, the symbol error rate （SER） is tested, and the computation complexity of the proposed scheme is analyzed. Computer simulation results show that the proposed pre-processing filter can effectively mitigate IBI and ICI and the performance can be improved. Compared with pre-processing approaches at the transmitter based on full CSI, the proposed scheme has high spectral efficiency, limited CSI feedback and low computation complexity.
文摘The Chang＇e-3 （CE-3） mission is China＇s first exploration mission on the surface of the Moon that uses a lander and a rover. Eight instruments that form the scientific payloads have the following objectives： （1） investigate the morphological features and geological structures at the landing site; （2） integrated in-situ analysis of minerals and chemical compositions; （3） integrated exploration of the structure of the lunar interior; （4） exploration of the lunar-terrestrial space environment, lunar sur- face environment and acquire Moon-based ultraviolet astronomical observations. The Ground Research and Application System （GRAS） is in charge of data acquisition and pre-processing, management of the payload in orbit, and managing the data products and their applications. The Data Pre-processing Subsystem （DPS） is a part of GRAS. The task of DPS is the pre-processing of raw data from the eight instruments that are part of CE-3, including channel processing, unpacking, package sorting, calibration and correction, identification of geographical location, calculation of probe azimuth angle, probe zenith angle, solar azimuth angle, and solar zenith angle and so on, and conducting quality checks. These processes produce Level 0, Level 1 and Level 2 data. The computing platform of this subsystem is comprised of a high-performance computing cluster, including a real-time subsystem used for processing Level 0 data and a post-time subsystem for generating Level 1 and Level 2 data. This paper de- scribes the CE-3 data pre-processing method, the data pre-processing subsystem, data classification, data validity and data products that are used for scientific studies.
基金supported by the National Natural Science Foundation of China(Grant No.41630754)the State Key Laboratory of Cryospheric Science(SKLCS-ZZ-2017)CAS Key Technology Talent Program and Open Foundation of State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering(2017490711)
文摘High-resolution ice core records covering long time spans enable reconstruction of the past climatic and environmental conditions allowing the investigation of the earth system's evolution.Preprocessing of ice cores has direct impacts on the data quality control for further analysis since the conventional ice core processing is time-consuming,produces qualitative data,leads to ice mass loss,and leads to risks of potential secondary pollution.However,over the past several decades,preprocessing of ice cores has received less attention than the improvement of ice drilling,the analytical methodology of various indices,and the researches on the climatic and environmental significance of ice core records.Therefore,this papers reviews the development of the processing for ice cores including framework,design as well as materials,analyzes the technical advantages and disadvantages of the different systems.In the past,continuous flowanalysis(CFA)has been successfully applied to process the polar ice cores.However,it is not suitable for ice cores outside polar region because of high level of particles,the memory effect between samples,and the filtration before injection.Ice core processing is a subtle and professional operation due to the fragility of the nonmetallic materials and the random distribution of particles and air bubbles in ice cores,which aggravates uncertainty in the measurements.The future developments of CFA are discussed in preprocessing,memory effect,challenge for brittle ice,coupling with real-time analysis and optimization of CFA in the field.Furthermore,non-polluting cutters with many different configurations could be designed to cut and scrape in multiple directions and to separate inner and outer portions of the core.This system also needs to be coupled with streamlined operation of packaging,coding,and stacking that can be implemented at high resolution and rate,avoiding manual intervention.At the same time,information of the longitudinal sections could be scanned andidentified,and then classified to obtain quantitative data.In addition,irregular ice volume and weight can also be obtained accurately.These improvements are recorded automatically via user-friendly interfaces.These innovations may be applied to other paleomedias with similar features and needs.
文摘Mathematical morphology is widely applicated in digital image procesing.Vari- ary morphology construction and algorithm being developed are used in deferent digital image processing.The basic idea of mathematical morphology is to use construction ele- ment measure image morphology for solving understand problem.The article presented advanced cellular neural network that forms mathematical morphological cellular neural network (MMCNN) equation to be suit for mathematical morphology filter.It gave the theo- ries of MMCNN dynamic extent and stable state.It is evidenced that arrived mathematical morphology filter through steady of dynamic process in definite condition.
