AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).MET...AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).METHODS:A cohort participant without DR diagnosed with T1DM,underwent comprehensive ophthalmologic evaluation,optical coherence tomography angiography retinal structural and microvascular density analysis,and systemic parameter assessment.Multiple linear regression analysis was used to investigate the impact of systemic parameters on retinal alterations in distinct gender groups.RESULTS:A total of 182 individuals were included,consisting of 85 males(mean age 23.28±12.75y)and 97 females(mean age 22.98±13.68y).Males exhibited significantly greater thickness in both the internal retinal layer and the entire retina compared to females(P<0.01),whereas females had higher densities of deep retinal vessels and choroidal capillaries(P<0.05).Additionally,glycemic control was found to have a notable influence on retinal thickness in males(P<0.05),while insulin function had a more pronounced impact on retinal structure in females(P<0.01).Furthermore,a significant correlation was observed between thyroid function markers and retinal parameters in both male and female(P<0.05).CONCLUSION:Sex differences in alterations in retinal structure and microcirculation are observed in individuals with T1DM prior to the development of clinical DR,with a noted association between these changes and systemic parameters.展开更多
Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing s...Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing studies often lack comparative analysis of urban-rural differences and tend to focus excessively on behavior patterns while neglecting the dimension of energysaving awareness.With China’s urbanization rate reaching 66.16%,understanding such regional disparities has become increasingly important.To address these research gaps,this study conducts a large-scale survey on space cooling behaviors among residents in Beijing,a representative Chinese megacity.It should be noted that living standards in such megacities are generally higher than the national average,which may shape distinctive energy-use profiles.Analyzing 1573valid samples(1064 urban/442 rural)in 2024,this study employed K-Prototypes and K-Modes clustering to identify typical cooling behavior and energy-saving awareness pattems,followed by Kendall/Chi-square correlation tests and XGBoost importance analysis to determine key influencing factors,with subsequent urban-rural comparative analysis.Results indicate that urban residents are primarily heat-sensitive or heat-tolerant,with a secondary patten of mid-low temperature preference,and generally exhibit long cooling durations;rural behavior is dominated by heat-tolerant type,followed by heat-sensitive,mid-low temperature preference,and never-on types as secondary patterns;both urban and rural areas exhibit energy-savingawareness characterized by low consumption-lowwillingness,though urban areas show marginally higher motivation;energy-saving awareness correlates with cooling behavior in rural areas,but this relationship weakens significantly in urban contexts.展开更多
With China’s accession to WTO,public signs are frequently seen in cities.However,there are lots of pragmatic errors and many improper translation,which we can find everywhere.In addition,this situation exerts serious...With China’s accession to WTO,public signs are frequently seen in cities.However,there are lots of pragmatic errors and many improper translation,which we can find everywhere.In addition,this situation exerts serious side effects on our international image in foreign exchange.In order to regulate translation and application of public signs and even with an aim to bring about the realization of globalization,this paper discusses and analyzes some translating strategies and principles from the perspective of cultural differences and pragmatics.展开更多
The intercultural pragmatics is a field that is concerned broadly in recent years. Cultural difference is an essential factor that caused the pragmatic failure. It is an inevitable fact that Chinese and British have d...The intercultural pragmatics is a field that is concerned broadly in recent years. Cultural difference is an essential factor that caused the pragmatic failure. It is an inevitable fact that Chinese and British have different language habit because of different cultural backgrounds. As a result, pragmatic failure has an effect on the access to information and cause communication misunderstanding even influence communication going with a swing. This thesis tries to analyze the pragmatic failure in cross-cultural communication from the perspective of cultural differences, find the reason and put forward the measures that can solve this problem.展开更多
Because of differences in habits and customs, logical thinking, as well as cultural values between Chinese and English,there are pragmatics differences in social greetings, thanks, banquets, invitations, and apologies...Because of differences in habits and customs, logical thinking, as well as cultural values between Chinese and English,there are pragmatics differences in social greetings, thanks, banquets, invitations, and apologies language communication occasions. Thus, it is important to explore the language habits with different culture backgrounds of language communications and language features and study the pragmatic failure led by people using a foreign language because of the differences of social and cultural factors.展开更多
The paper employs the method of discourse analysis to analyze males' and females' differences in cross-gender conversations in Gossip Girl from the perspective of Searle's Indirect Speech Act Theory, Grice...The paper employs the method of discourse analysis to analyze males' and females' differences in cross-gender conversations in Gossip Girl from the perspective of Searle's Indirect Speech Act Theory, Grice's Cooperative Principle, and Leech's Politeness Principle. The study found that females tend to abide by Cooperative Principle, while males are more likely to fl out the CP, and that female characters are used to making requests or suggestions by raising question in a euphemistic way; while males concern less about courtesy, women always attach a great deal of importance to saving others' face in daily conversation. The paper contributed to reducing misunderstanding in cross-gender communication.展开更多
Language is not only a tool for communication but a part of culture as well.If the understanding of different culture background is neglected in communication,pragmatic failure must easily be produced.According to pra...Language is not only a tool for communication but a part of culture as well.If the understanding of different culture background is neglected in communication,pragmatic failure must easily be produced.According to pragmatic theories,this article analyses various kinds of pragmatic failure in communication because of cultural differences with simple examples.Moreover,it probes into the influence of language pragmatic failure on the effect of communication.展开更多
This study explores the impact of intergenerational differences on farmers' terrace abandonment in response to increasing intergenerational differentiation among rural households and the practical issue of terrace...This study explores the impact of intergenerational differences on farmers' terrace abandonment in response to increasing intergenerational differentiation among rural households and the practical issue of terrace abandonment. Logit and Tobit models are employed to conduct empirical analysis and it is found that terrace abandonment increases sequentially among the new, middle, and old generations, confirming that intergenerational differences significantly influence whether farmers abandon terraces and the terrace abandonment scale. Village characteristics and government subsidies significantly influence farmers' terrace abandonment. An increase in the number of migrant workers in the village increases terrace abandonment among new and middle generation farmers, whereas an increase in the distance from the village to the county significantly increases terrace abandonment among old generation farmers. An increase in the village's total population significantly reduces terrace abandonment among new generation farmers. An increase in government subsidies significantly reduces terrace abandonment among middle and old generation farmers. The impact of intergenerational differences on terrace abandonment is more pronounced in low-altitude areas. To reduce terrace abandonment, it is necessary to promote terrace transfer, develop characteristic agriculture, improve terrace farming subsidies, and propose targeted strategies for the different generations of farmers.展开更多
Background: For nursing students, gathering social information is essential for understanding healthcare and social issues and developing critical thinking and decision-making skills. However, the choice of informatio...Background: For nursing students, gathering social information is essential for understanding healthcare and social issues and developing critical thinking and decision-making skills. However, the choice of information sources varies by age and individual habits. With the widespread use of the internet, there are notable differences between younger and older generations in their reliance on the internet versus traditional media sources like newspapers and television. Given the wide age range and diverse backgrounds of nursing students, understanding generational differences in information-gathering methods is important for implementing effective education. Purpose: The purpose of this study is to identify how nursing students in different age groups obtain social information and to examine media usage trends by age group. Additionally, we aim to use the findings to provide insights into effective information dissemination methods in nursing education. Results: The results showed that nursing students in their teens to forties, regardless of gender, primarily relied on the internet as their main information source, with television playing a secondary role. In contrast, students in their fifties tended to obtain information more often from newspapers and television than from the internet. This highlights an age-related difference in preferred information sources, with older students showing a greater reliance on traditional media. Conclusions: This study demonstrates that nursing students use different information-gathering methods based on their age, suggesting a need to custo-mize information dissemination strategies in nursing education. Digital media may be more effective for younger students, while traditional media or printed materials might better serve older students. Educational institutions should consider these generational differences in media usage and adopt strategies that meet the diverse needs of their student populations.展开更多
Flipped is a book written by American author Wendelin Van Draanen. It is a novel about young teenagers and was adapted into the famous film of the same name in 2010. The thesis employs speech acts, as pioneered by Joh...Flipped is a book written by American author Wendelin Van Draanen. It is a novel about young teenagers and was adapted into the famous film of the same name in 2010. The thesis employs speech acts, as pioneered by John Austin and further developed by John Searle, to investigate the influence of dialogues on characterization and plot development in Flipped. By exploring the theory of speech acts presented in dialogues between characters, the author deciphers the underlying intentions embodied in the dialogues and demonstrates the importance of the use of speech acts in dialogues in revealing the characters, driving the development of the plot and expressing the theme of the text.展开更多
With the popularization of social media,stickers have become an important tool for young students to express themselves and resist mainstream culture due to their unique visual and emotional expressiveness.Most existi...With the popularization of social media,stickers have become an important tool for young students to express themselves and resist mainstream culture due to their unique visual and emotional expressiveness.Most existing studies focus on the negative impacts of spoof stickers,while paying insufficient attention to their positive functions.From the perspective of multimodal metaphor,this paper uses methods such as virtual ethnography and image-text analysis to clarify the connotation of stickers,understand the evolution of their digital dissemination forms,and explore the multiple functions of subcultural stickers in the social interactions between teachers and students.Young students use stickers to convey emotions and information.Their expressive function,social function,and cultural metaphor function progress in a progressive manner.This not only shapes students’values but also promotes self-expression and teacher-student interaction.It also reminds teachers to correct students’negative thoughts by using stickers,achieving the effect of“cultivating and influencing people through culture.”展开更多
Objective:Near vision loss(NVL)is one of the leading causes of visual impairment worldwide,exerting a profound impact on individual quality of life and socio-economic development.This study aims to analyze the burden ...Objective:Near vision loss(NVL)is one of the leading causes of visual impairment worldwide,exerting a profound impact on individual quality of life and socio-economic development.This study aims to analyze the burden of NVL in China by sex and age groups from 1990 to 2021 and to project trends over the next 15 years.Methods:Using data from the Global Burden of Disease(GBD)2021 database,we conducted descriptive analyses of NVL prevalence in China,calculated age-standardized prevalence rates(ASPR)and age-standardized disability-adjusted life years rates(ASDR)to compare burden differences between sexes and age groups,and applied an autoregressive integrated moving average(ARIMA)model to predict NVL trends for the next 15 years.The model selection was based on best-fit criteria to ensure reliable projections.Results:From 1990 to 2021,China’s ASPR of NVL rose from 10096.24/100000 to 15624.54/100000,and ASDR increased from 101.75/100000 to 158.75/100000.In 2021,ASPR(16551.70/100000)and ASDR(167.69/100000)were higher among females than males(14686.21/100000 and 149.76/100000,respectively).China ranked highest globally in both NVL cases and disability-adjusted life years(DALYs),with female burden significantly exceeding male burden.Projections indicated this trend and sex gap will persist until 2036.Compared with 1990,the prevalence cases and DALYs increased by 239.20%and 238.82%,respectively in 2021,with the highest burden among females and the 55−59 age group.The ARIMA model predicted continued increases in prevalence and DALYs by 2036,with females maintaining a higher burden than males.Conclusion:This study reveals a marked increase in the NVL burden in China and predicts continued growth in the coming years.Public health policies should prioritize NVL prevention and control,with special attention to women and middle-aged populations to mitigate long-term societal and health impacts.展开更多
BACKGROUND Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis(AIS),affecting individuals across both sex and age groups.AIM To explore the network structu...BACKGROUND Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis(AIS),affecting individuals across both sex and age groups.AIM To explore the network structure of depression and anxiety symptoms,with a focus on identifying differences at the symptom level between sex and age subgroups.METHODS A total of 1955 participants diagnosed with AIS aged 10-18 years were assessed using the Patient Health Questionnaire Depression Scale(PHO-9)and the Generalized Anxiety Disorder Scale(GAD-7),and 765 patients exhibiting PHQ-9 or GAD-7 scores ≥ 5 were enrolled in our study. Network analysis and network comparison tests were utilized toconstruct and compare the depression-anxiety symptoms networks among sex and age subgroups.RESULTSThe results revealed GAD3 “Excessive worry” and PHQ2 “Sad mood” were the most significant central symptomsin all subgroups, while “Sad mood” had higher strength than “Excessive worry” in the lower age group. In thenetwork comparisons, the female network exhibited tighter connectivity, especially on GAD6 “Irritability” andGAD2 “Uncontrollable worry”, while only PHQ3 “Sleep” and PHQ9 “Suicidal ideation” had differences at thelocal level in the lower age group.CONCLUSIONSeveral interventions targeting excessive worry and sad mood could reduce the risk of depression and anxietysymptoms in the AIS population. Furthermore, specific anxiety symptoms in females, along with sleep disturbancesand suicidal ideation in the lower age group, should be addressed at an early stage to prevent significantdisruptions in mental health trajectories.展开更多
Experimental mice play a critical role in biomedical research.The phenotype and application of different substrains vary due to genetic differentiation and variation.To ensure validity and reliability of results,it is...Experimental mice play a critical role in biomedical research.The phenotype and application of different substrains vary due to genetic differentiation and variation.To ensure validity and reliability of results,it is imperative to adhere to standardized experiments and controls.This paper objectively reviews the origin,differentiation,and phenotypic and genetic differences between the C57BL/6 and BALB/c mouse substrains.Furthermore,an optimal selection strategy is proposed based on the genetic quality control technology to facilitate the precise application of these two mouse substrains.展开更多
This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the foc...This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the focus of translation from static linguistic equivalence to more dynamic communicative effectiveness.This paper advocates the flexible application of various strategies.These include literal translation,free translation,transliteration with annotation,and adaptive translation based on the target audience’s cognitive context.The paper innovatively proposes digitally-enabled teaching implementation paths,including constructing modular online courses,building intelligent terminology case databases,conducting cloud-based workshops on translation,and implementing industry-academia collaborative project practices.These aim to reshape the teaching process utilizing digital technology,effectively cultivating higher vocational students’cultural communication abilities and practical translation skills,thereby providing high-quality language service talent support for the internationalization of Chinese tea culture.展开更多
Empathy is crucial for communication and survival for individuals.Whether empathy in pain contagion shows sex differences and its underlying mechanisms remain unclear.Here,we report that pain contagion can occur in st...Empathy is crucial for communication and survival for individuals.Whether empathy in pain contagion shows sex differences and its underlying mechanisms remain unclear.Here,we report that pain contagion can occur in stranger female rats,but not in stranger males.Blocking oxytocin receptors in the anterior cingulate cortex(ACC)suppressed pain contagion in female strangers,while oxytocin administration induced pain contagion in male strangers.In vitro,corticosterone reduces neuronal activation by oxytocin.During male stranger interactions,higher corticosterone decreased oxytocin receptor-positive neuronal activity in the ACC,suppressing pain contagion.These findings highlight the role of oxytocin in pain contagion and suggest that sex differences in empathy may be determined by the balance of oxytocin and corticosterone in the ACC.This study suggests an approach for the treatment of certain mental disorders associated with abnormal empathy,such as autism and depression.展开更多
Population migration data derived from location-based services has often been used to delineate population flows between cities or construct intercity relationship networks to reveal and explore the complex interactio...Population migration data derived from location-based services has often been used to delineate population flows between cities or construct intercity relationship networks to reveal and explore the complex interaction patterns underlying human activities.Nevertheless,the inherent heterogeneity in multimodal migration big data has been ignored.This study conducts an in-depth comparison and quantitative analysis through a comprehensive lens of spatial association.Initially,the intercity interactive networks in China were constructed,utilizing migration data from Baidu and AutoNavi collected during the same time period.Subsequently,the characteristics and spatial structure similarities of the two types of intercity interactive networks were quantitatively assessed and analyzed from overall(network)and local(node)perspectives.Furthermore,the precision of these networks at the local scale is corroborated by constructing an intercity network from mobile phone(MP)data.Results indicate that the intercity interactive networks in China,as delineated by Baidu and AutoNavi migration flows,exhibit a high degree of structure equivalence.The correlation coefficient between these two networks is 0.874.Both networks exhibit a pronounced spatial polarization trend and hierarchical structure.This is evident in their distinct core and peripheral structures,as well as in the varying importance and influence of different nodes within the networks.Nevertheless,there are notable differences worthy of attention.Baidu intercity interactive network exhibits pronounced cross-regional effects,and its high-level interactions are characterized by a“rich-club”phenomenon.The AutoNavi intercity interactive network presents a more significant distance attenuation effect,and the high-level interactions display a gradient distribution pattern.Notably,there exists a substantial correlation between the AutoNavi and MP networks at the local scale,evidenced by a high correlation coefficient of 0.954.Furthermore,the“spatial dislocations”phenomenon was observed within the spatial structures at different levels,extracted from the Baidu and AutoNavi intercity networks.However,the measured results of network spatial structure similarity from three dimensions,namely,node location,node size,and local structure,indicate a relatively high similarity and consistency between the two networks.展开更多
基金Supported by Natural Science Foundation of Hunan Province(No.2023JJ70017No.2025JJ50627)Peak Climbing Project of Optometry Hospital Affiliated to Wenzhou Medical University。
文摘AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).METHODS:A cohort participant without DR diagnosed with T1DM,underwent comprehensive ophthalmologic evaluation,optical coherence tomography angiography retinal structural and microvascular density analysis,and systemic parameter assessment.Multiple linear regression analysis was used to investigate the impact of systemic parameters on retinal alterations in distinct gender groups.RESULTS:A total of 182 individuals were included,consisting of 85 males(mean age 23.28±12.75y)and 97 females(mean age 22.98±13.68y).Males exhibited significantly greater thickness in both the internal retinal layer and the entire retina compared to females(P<0.01),whereas females had higher densities of deep retinal vessels and choroidal capillaries(P<0.05).Additionally,glycemic control was found to have a notable influence on retinal thickness in males(P<0.05),while insulin function had a more pronounced impact on retinal structure in females(P<0.01).Furthermore,a significant correlation was observed between thyroid function markers and retinal parameters in both male and female(P<0.05).CONCLUSION:Sex differences in alterations in retinal structure and microcirculation are observed in individuals with T1DM prior to the development of clinical DR,with a noted association between these changes and systemic parameters.
文摘Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing studies often lack comparative analysis of urban-rural differences and tend to focus excessively on behavior patterns while neglecting the dimension of energysaving awareness.With China’s urbanization rate reaching 66.16%,understanding such regional disparities has become increasingly important.To address these research gaps,this study conducts a large-scale survey on space cooling behaviors among residents in Beijing,a representative Chinese megacity.It should be noted that living standards in such megacities are generally higher than the national average,which may shape distinctive energy-use profiles.Analyzing 1573valid samples(1064 urban/442 rural)in 2024,this study employed K-Prototypes and K-Modes clustering to identify typical cooling behavior and energy-saving awareness pattems,followed by Kendall/Chi-square correlation tests and XGBoost importance analysis to determine key influencing factors,with subsequent urban-rural comparative analysis.Results indicate that urban residents are primarily heat-sensitive or heat-tolerant,with a secondary patten of mid-low temperature preference,and generally exhibit long cooling durations;rural behavior is dominated by heat-tolerant type,followed by heat-sensitive,mid-low temperature preference,and never-on types as secondary patterns;both urban and rural areas exhibit energy-savingawareness characterized by low consumption-lowwillingness,though urban areas show marginally higher motivation;energy-saving awareness correlates with cooling behavior in rural areas,but this relationship weakens significantly in urban contexts.
文摘With China’s accession to WTO,public signs are frequently seen in cities.However,there are lots of pragmatic errors and many improper translation,which we can find everywhere.In addition,this situation exerts serious side effects on our international image in foreign exchange.In order to regulate translation and application of public signs and even with an aim to bring about the realization of globalization,this paper discusses and analyzes some translating strategies and principles from the perspective of cultural differences and pragmatics.
文摘The intercultural pragmatics is a field that is concerned broadly in recent years. Cultural difference is an essential factor that caused the pragmatic failure. It is an inevitable fact that Chinese and British have different language habit because of different cultural backgrounds. As a result, pragmatic failure has an effect on the access to information and cause communication misunderstanding even influence communication going with a swing. This thesis tries to analyze the pragmatic failure in cross-cultural communication from the perspective of cultural differences, find the reason and put forward the measures that can solve this problem.
文摘Because of differences in habits and customs, logical thinking, as well as cultural values between Chinese and English,there are pragmatics differences in social greetings, thanks, banquets, invitations, and apologies language communication occasions. Thus, it is important to explore the language habits with different culture backgrounds of language communications and language features and study the pragmatic failure led by people using a foreign language because of the differences of social and cultural factors.
文摘The paper employs the method of discourse analysis to analyze males' and females' differences in cross-gender conversations in Gossip Girl from the perspective of Searle's Indirect Speech Act Theory, Grice's Cooperative Principle, and Leech's Politeness Principle. The study found that females tend to abide by Cooperative Principle, while males are more likely to fl out the CP, and that female characters are used to making requests or suggestions by raising question in a euphemistic way; while males concern less about courtesy, women always attach a great deal of importance to saving others' face in daily conversation. The paper contributed to reducing misunderstanding in cross-gender communication.
文摘Language is not only a tool for communication but a part of culture as well.If the understanding of different culture background is neglected in communication,pragmatic failure must easily be produced.According to pragmatic theories,this article analyses various kinds of pragmatic failure in communication because of cultural differences with simple examples.Moreover,it probes into the influence of language pragmatic failure on the effect of communication.
基金Key Program of National Natural Science Foundation of China,No.41930757National Natural Science Foundation of China,No.42371285。
文摘This study explores the impact of intergenerational differences on farmers' terrace abandonment in response to increasing intergenerational differentiation among rural households and the practical issue of terrace abandonment. Logit and Tobit models are employed to conduct empirical analysis and it is found that terrace abandonment increases sequentially among the new, middle, and old generations, confirming that intergenerational differences significantly influence whether farmers abandon terraces and the terrace abandonment scale. Village characteristics and government subsidies significantly influence farmers' terrace abandonment. An increase in the number of migrant workers in the village increases terrace abandonment among new and middle generation farmers, whereas an increase in the distance from the village to the county significantly increases terrace abandonment among old generation farmers. An increase in the village's total population significantly reduces terrace abandonment among new generation farmers. An increase in government subsidies significantly reduces terrace abandonment among middle and old generation farmers. The impact of intergenerational differences on terrace abandonment is more pronounced in low-altitude areas. To reduce terrace abandonment, it is necessary to promote terrace transfer, develop characteristic agriculture, improve terrace farming subsidies, and propose targeted strategies for the different generations of farmers.
文摘Background: For nursing students, gathering social information is essential for understanding healthcare and social issues and developing critical thinking and decision-making skills. However, the choice of information sources varies by age and individual habits. With the widespread use of the internet, there are notable differences between younger and older generations in their reliance on the internet versus traditional media sources like newspapers and television. Given the wide age range and diverse backgrounds of nursing students, understanding generational differences in information-gathering methods is important for implementing effective education. Purpose: The purpose of this study is to identify how nursing students in different age groups obtain social information and to examine media usage trends by age group. Additionally, we aim to use the findings to provide insights into effective information dissemination methods in nursing education. Results: The results showed that nursing students in their teens to forties, regardless of gender, primarily relied on the internet as their main information source, with television playing a secondary role. In contrast, students in their fifties tended to obtain information more often from newspapers and television than from the internet. This highlights an age-related difference in preferred information sources, with older students showing a greater reliance on traditional media. Conclusions: This study demonstrates that nursing students use different information-gathering methods based on their age, suggesting a need to custo-mize information dissemination strategies in nursing education. Digital media may be more effective for younger students, while traditional media or printed materials might better serve older students. Educational institutions should consider these generational differences in media usage and adopt strategies that meet the diverse needs of their student populations.
文摘Flipped is a book written by American author Wendelin Van Draanen. It is a novel about young teenagers and was adapted into the famous film of the same name in 2010. The thesis employs speech acts, as pioneered by John Austin and further developed by John Searle, to investigate the influence of dialogues on characterization and plot development in Flipped. By exploring the theory of speech acts presented in dialogues between characters, the author deciphers the underlying intentions embodied in the dialogues and demonstrates the importance of the use of speech acts in dialogues in revealing the characters, driving the development of the plot and expressing the theme of the text.
文摘With the popularization of social media,stickers have become an important tool for young students to express themselves and resist mainstream culture due to their unique visual and emotional expressiveness.Most existing studies focus on the negative impacts of spoof stickers,while paying insufficient attention to their positive functions.From the perspective of multimodal metaphor,this paper uses methods such as virtual ethnography and image-text analysis to clarify the connotation of stickers,understand the evolution of their digital dissemination forms,and explore the multiple functions of subcultural stickers in the social interactions between teachers and students.Young students use stickers to convey emotions and information.Their expressive function,social function,and cultural metaphor function progress in a progressive manner.This not only shapes students’values but also promotes self-expression and teacher-student interaction.It also reminds teachers to correct students’negative thoughts by using stickers,achieving the effect of“cultivating and influencing people through culture.”
基金supported by the Natural Science Foundation of Hunan Province(2023JJ30817)Hunan Provincial Natural Science Foundation-Hengyang City Joint Fund Project(2025JJ70129)+1 种基金Changsha Natural Science Foundation(kq2403057)China。
文摘Objective:Near vision loss(NVL)is one of the leading causes of visual impairment worldwide,exerting a profound impact on individual quality of life and socio-economic development.This study aims to analyze the burden of NVL in China by sex and age groups from 1990 to 2021 and to project trends over the next 15 years.Methods:Using data from the Global Burden of Disease(GBD)2021 database,we conducted descriptive analyses of NVL prevalence in China,calculated age-standardized prevalence rates(ASPR)and age-standardized disability-adjusted life years rates(ASDR)to compare burden differences between sexes and age groups,and applied an autoregressive integrated moving average(ARIMA)model to predict NVL trends for the next 15 years.The model selection was based on best-fit criteria to ensure reliable projections.Results:From 1990 to 2021,China’s ASPR of NVL rose from 10096.24/100000 to 15624.54/100000,and ASDR increased from 101.75/100000 to 158.75/100000.In 2021,ASPR(16551.70/100000)and ASDR(167.69/100000)were higher among females than males(14686.21/100000 and 149.76/100000,respectively).China ranked highest globally in both NVL cases and disability-adjusted life years(DALYs),with female burden significantly exceeding male burden.Projections indicated this trend and sex gap will persist until 2036.Compared with 1990,the prevalence cases and DALYs increased by 239.20%and 238.82%,respectively in 2021,with the highest burden among females and the 55−59 age group.The ARIMA model predicted continued increases in prevalence and DALYs by 2036,with females maintaining a higher burden than males.Conclusion:This study reveals a marked increase in the NVL burden in China and predicts continued growth in the coming years.Public health policies should prioritize NVL prevention and control,with special attention to women and middle-aged populations to mitigate long-term societal and health impacts.
基金Supported by The Sanming Project of Medicine in Shenzhen,No.SZSM202211003Shenzhen-Hong Kong Jointly Funded Project,Shenzhen Science and Technology Program,No.SGDX20230116093645007+1 种基金Shenzhen Second People's Hospital Clinical Project,No.20243357003Shenzhen Medical Research Fund,No.B2303005.
文摘BACKGROUND Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis(AIS),affecting individuals across both sex and age groups.AIM To explore the network structure of depression and anxiety symptoms,with a focus on identifying differences at the symptom level between sex and age subgroups.METHODS A total of 1955 participants diagnosed with AIS aged 10-18 years were assessed using the Patient Health Questionnaire Depression Scale(PHO-9)and the Generalized Anxiety Disorder Scale(GAD-7),and 765 patients exhibiting PHQ-9 or GAD-7 scores ≥ 5 were enrolled in our study. Network analysis and network comparison tests were utilized toconstruct and compare the depression-anxiety symptoms networks among sex and age subgroups.RESULTSThe results revealed GAD3 “Excessive worry” and PHQ2 “Sad mood” were the most significant central symptomsin all subgroups, while “Sad mood” had higher strength than “Excessive worry” in the lower age group. In thenetwork comparisons, the female network exhibited tighter connectivity, especially on GAD6 “Irritability” andGAD2 “Uncontrollable worry”, while only PHQ3 “Sleep” and PHQ9 “Suicidal ideation” had differences at thelocal level in the lower age group.CONCLUSIONSeveral interventions targeting excessive worry and sad mood could reduce the risk of depression and anxietysymptoms in the AIS population. Furthermore, specific anxiety symptoms in females, along with sleep disturbancesand suicidal ideation in the lower age group, should be addressed at an early stage to prevent significantdisruptions in mental health trajectories.
基金National Key R&D Program of China,Grant/Award Number:2021YFF0703200Key Technology Fund of the National Institutes for Food and Drug Control,Grant/Award Number:GJJS-2022-1-5。
文摘Experimental mice play a critical role in biomedical research.The phenotype and application of different substrains vary due to genetic differentiation and variation.To ensure validity and reliability of results,it is imperative to adhere to standardized experiments and controls.This paper objectively reviews the origin,differentiation,and phenotypic and genetic differences between the C57BL/6 and BALB/c mouse substrains.Furthermore,an optimal selection strategy is proposed based on the genetic quality control technology to facilitate the precise application of these two mouse substrains.
基金Special Project of Higher Education in the 2023,Educational Science Planning Project of the Leading Group Office of the Guangdong Provincial Educational Science Planning,“Research on the New Forms of Foreign Language Teaching in Guangdong Higher Vocational Colleges under the Background of Education Digitization”(Project No.:2023GXJK1052)。
文摘This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the focus of translation from static linguistic equivalence to more dynamic communicative effectiveness.This paper advocates the flexible application of various strategies.These include literal translation,free translation,transliteration with annotation,and adaptive translation based on the target audience’s cognitive context.The paper innovatively proposes digitally-enabled teaching implementation paths,including constructing modular online courses,building intelligent terminology case databases,conducting cloud-based workshops on translation,and implementing industry-academia collaborative project practices.These aim to reshape the teaching process utilizing digital technology,effectively cultivating higher vocational students’cultural communication abilities and practical translation skills,thereby providing high-quality language service talent support for the internationalization of Chinese tea culture.
基金supported by the Shenzhen.Science and Technology Program(JCYJ20220818100615033,JCYJ20200109141433384,and KQTD20200820113040070)the National Natural Science Foundation of China(NSFC82471250 and 82350710225).
文摘Empathy is crucial for communication and survival for individuals.Whether empathy in pain contagion shows sex differences and its underlying mechanisms remain unclear.Here,we report that pain contagion can occur in stranger female rats,but not in stranger males.Blocking oxytocin receptors in the anterior cingulate cortex(ACC)suppressed pain contagion in female strangers,while oxytocin administration induced pain contagion in male strangers.In vitro,corticosterone reduces neuronal activation by oxytocin.During male stranger interactions,higher corticosterone decreased oxytocin receptor-positive neuronal activity in the ACC,suppressing pain contagion.These findings highlight the role of oxytocin in pain contagion and suggest that sex differences in empathy may be determined by the balance of oxytocin and corticosterone in the ACC.This study suggests an approach for the treatment of certain mental disorders associated with abnormal empathy,such as autism and depression.
基金National Natural Science Foundation of China,No.42361040。
文摘Population migration data derived from location-based services has often been used to delineate population flows between cities or construct intercity relationship networks to reveal and explore the complex interaction patterns underlying human activities.Nevertheless,the inherent heterogeneity in multimodal migration big data has been ignored.This study conducts an in-depth comparison and quantitative analysis through a comprehensive lens of spatial association.Initially,the intercity interactive networks in China were constructed,utilizing migration data from Baidu and AutoNavi collected during the same time period.Subsequently,the characteristics and spatial structure similarities of the two types of intercity interactive networks were quantitatively assessed and analyzed from overall(network)and local(node)perspectives.Furthermore,the precision of these networks at the local scale is corroborated by constructing an intercity network from mobile phone(MP)data.Results indicate that the intercity interactive networks in China,as delineated by Baidu and AutoNavi migration flows,exhibit a high degree of structure equivalence.The correlation coefficient between these two networks is 0.874.Both networks exhibit a pronounced spatial polarization trend and hierarchical structure.This is evident in their distinct core and peripheral structures,as well as in the varying importance and influence of different nodes within the networks.Nevertheless,there are notable differences worthy of attention.Baidu intercity interactive network exhibits pronounced cross-regional effects,and its high-level interactions are characterized by a“rich-club”phenomenon.The AutoNavi intercity interactive network presents a more significant distance attenuation effect,and the high-level interactions display a gradient distribution pattern.Notably,there exists a substantial correlation between the AutoNavi and MP networks at the local scale,evidenced by a high correlation coefficient of 0.954.Furthermore,the“spatial dislocations”phenomenon was observed within the spatial structures at different levels,extracted from the Baidu and AutoNavi intercity networks.However,the measured results of network spatial structure similarity from three dimensions,namely,node location,node size,and local structure,indicate a relatively high similarity and consistency between the two networks.
