[Objective] To study the cocoon traits of wild silkworm descendants. [Method] In the selective breeding of domesticated raising wild silkworm and wild silkworm descendants, investigation on the traits of the built coc...[Objective] To study the cocoon traits of wild silkworm descendants. [Method] In the selective breeding of domesticated raising wild silkworm and wild silkworm descendants, investigation on the traits of the built cocoons was carried out. [Result] The pointed traits of cocoons displayed obviously in the wild silkworm descendants, its pointed parts were consistent with the rear part of silkworm chrysalis, and the female silkworm has slight difference, indicating the silkworm co- coon pointed trait was hereditary. [Conclusion] This study provided references for the study of silkworm cocoon traits of wild silkworm descendant and guides the selective breeding of silkworm variety.展开更多
Computations and Experiments were performed to get an understanding of the flow field around a rectangular supersonic air intake with pointed cowl [90°] at different back pressures for Mach 2.2. The effect of Cow...Computations and Experiments were performed to get an understanding of the flow field around a rectangular supersonic air intake with pointed cowl [90°] at different back pressures for Mach 2.2. The effect of Cowl shape on the ramp surface pressure distribution is discussed and compared with existing V-Notch [90°] intake model at free exit condition. It was found that using pointed cowl [90°] intake model, a better pressure recovery was achieved compared to the V-Notch [90°] intake model at Mach 2.2. Both Pointed and V-Notch intake models showed good starting characteristics. For change in back pressure, the occurence of normal shock, flow separation zone and flow reversal were observed. All experiments are performed only for the Pointed cowl [90°] intake model. All the 3-D computations were performed by using software available at B.I.T, Mesra, Ranchi.展开更多
On October 26,the Ministry of Foreign Affairs of China announced the appointment of Ambassador Xu Bu as the President of China Institute of International Studies(CIIS).Zheng Zeguang,Vice Minister of Foreign Affairs,at...On October 26,the Ministry of Foreign Affairs of China announced the appointment of Ambassador Xu Bu as the President of China Institute of International Studies(CIIS).Zheng Zeguang,Vice Minister of Foreign Affairs,attended the appointment ceremony and expressed his hope for Ambassador Xu to unite the CIIS leadership and staff under the guidance of the Foreign Ministry and elevate the top-level think tank to a new height.展开更多
There is an amazing healing power in the novel The Country of the Pointed Firs embodied in nature and the local people. Reading this novel, everyone can be the narrator who has experienced a journey of healing in Dunn...There is an amazing healing power in the novel The Country of the Pointed Firs embodied in nature and the local people. Reading this novel, everyone can be the narrator who has experienced a journey of healing in Dunnet Landing during her interactions with the coastal natural sceneries and the lovely local residents in that in those small islands.展开更多
We obtain a necessary condition for a strictly weakly integral generalized Tambara-Yamagami fusion category to be braided.Then we use this result to classify braided extensions of a pointed fusion category with prime ...We obtain a necessary condition for a strictly weakly integral generalized Tambara-Yamagami fusion category to be braided.Then we use this result to classify braided extensions of a pointed fusion category with prime dimension.展开更多
The Hard X-ray Modulation Telescope （HXMT） is an X-ray astronomy satellite consisting of three slat-collimated instruments, the High Energy X-ray Instrument （HE）, the Medium Energy X-ray Instrument （ME）, and the...The Hard X-ray Modulation Telescope （HXMT） is an X-ray astronomy satellite consisting of three slat-collimated instruments, the High Energy X-ray Instrument （HE）, the Medium Energy X-ray Instrument （ME）, and the Low Energy X-ray Instrument （LE）. HXMT will carry out an all sky survey and make pointed observations in the 1-250 keV energy band. In order to get the source and background fluxes simultaneously in the pointed observations, two methods, i.e., the combined field of view （FOV） method and the off-axis pointing method are proposed in this paper. Comprehensive analyses of the sensitivities of the three instruments by using these two methods are presented, respectively. It is found that the off-axis pointing method has a higher sensitivity for HE and ME but a lower sensitivity for LE. Since the axes of the three instruments are aligned along the same direction, the off-axis pointing method is recommended as the main method in the pointed observation for HXMT; the combined FOV method can be used when LE is the most relevant instrument in order to satisfy the scientific objective of the observation.展开更多
In this paper we study the pointed representations of the Virasoro algebra.We show that unitary irreducible pointed representations of the Virasoro algebra are Harish-Chandra repre- sentations,thus they either are of ...In this paper we study the pointed representations of the Virasoro algebra.We show that unitary irreducible pointed representations of the Virasoro algebra are Harish-Chandra repre- sentations,thus they either are of highest or lowest weights or have all weight spaces of dimension 1.Further,we prove that unitary irreducible weight representations of Virasoro superalgebras are either of highest weights or of lowest weights,hence they are also Harish-Chandra representations.展开更多
Let T(G) be the Teichmüller space of a Fuchsian group G and T(G) be the pointed Teichmüller space of a corresponding pointed Fuchsian group G.We will discuss the existence of holomorphic sections of the proj...Let T(G) be the Teichmüller space of a Fuchsian group G and T(G) be the pointed Teichmüller space of a corresponding pointed Fuchsian group G.We will discuss the existence of holomorphic sections of the projection from the space M(G) of Beltrami coefficients for G to T(G) and of that from T(G) to T(G) as well.We will also study the biholomorphic isomorphisms between two pointed Teichmüller spaces.展开更多
We focus on the classification of pointed p^3-dimensional Hopf algebras H over any algebraically closed field of prime characteristic p 〉 0. In particular, we consider certain cases when the group of grouplike elemen...We focus on the classification of pointed p^3-dimensional Hopf algebras H over any algebraically closed field of prime characteristic p 〉 0. In particular, we consider certain cases when the group of grouplike elements is of order p or p^2 that is, when H is pointed but is not connected nor a group algebra. The structures of the associated graded algebra gr H are completely described as bosonizations of graded braided Hopf algebras over group algebras, and most of the lifting structures of H are given. This work provides many new examples of （parametrized） non-commutative, non-cocommutative finite- dimensional Hopf algebras in positive characteristic.展开更多
A contravaried bilinear pairing X on every M(ρ) × M(ρθ) is determined and it is provedthat M(ρ)is irreducible if and only if K is left nondegellerate. It is also proved that every cyclicpointed module is a qu...A contravaried bilinear pairing X on every M(ρ) × M(ρθ) is determined and it is provedthat M(ρ)is irreducible if and only if K is left nondegellerate. It is also proved that every cyclicpointed module is a quotient of some Verma-like poillted module; moreover if it is irreduciblethen it is a quotieDt of the Vermarlike poiDted module by the left kernel of some bilinearpairing K. In case the mass fUnction is symmetric, there exists a bilinear form on M(ρ). It isproved that unitals pointed modules are integrable. In addition, a characterization of the massfunctions of Kac-Moody algebras is given, which is a generalization of the finite dimensionalLie algebras case.展开更多
Neuromodulation techniques effectively intervene in cognitive function,holding considerable scientific and practical value in fields such as aerospace,medicine,life sciences,and brain research.These techniques utilize...Neuromodulation techniques effectively intervene in cognitive function,holding considerable scientific and practical value in fields such as aerospace,medicine,life sciences,and brain research.These techniques utilize electrical stimulation to directly or indirectly target specific brain regions,modulating neural activity and influencing broader brain networks,thereby regulating cognitive function.Regulating cognitive function involves an understanding of aspects such as perception,learning and memory,attention,spatial cognition,and physical function.To enhance the application of cognitive regulation in the general population,this paper reviews recent publications from the Web of Science to assess the advancements and challenges of invasive and non-invasive stimulation methods in modulating cognitive functions.This review covers various neuromodulation techniques for cognitive intervention,including deep brain stimulation,vagus nerve stimulation,and invasive methods using microelectrode arrays.The non-invasive techniques discussed include transcranial magnetic stimulation,transcranial direct current stimulation,transcranial alternating current stimulation,transcutaneous electrical acupoint stimulation,and time interference stimulation for activating deep targets.Invasive stimulation methods,which are ideal for studying the pathogenesis of neurological diseases,tend to cause greater trauma and have been less researched in the context of cognitive function regulation.Non-invasive methods,particularly newer transcranial stimulation techniques,are gentler and more appropriate for regulating cognitive functions in the general population.These include transcutaneous acupoint electrical stimulation using acupoints and time interference methods for activating deep targets.This paper also discusses current technical challenges and potential future breakthroughs in neuromodulation technology.It is recommended that neuromodulation techniques be combined with neural detection methods to better assess their effects and improve the accuracy of non-invasive neuromodulation.Additionally,researching closed-loop feedback neuromodulation methods is identified as a promising direction for future development.展开更多
Background:The medicinal material known as Os Draconis(Longgu)originates from fossilized remains of ancient mammals and is widely used in treating emotional and mental conditions.However,fossil resources are nonrenewa...Background:The medicinal material known as Os Draconis(Longgu)originates from fossilized remains of ancient mammals and is widely used in treating emotional and mental conditions.However,fossil resources are nonrenewable,and clinical demand is increasingly difficult to meet,leading to a proliferation of counterfeit products.During prolonged geological burial,static pressure from the surrounding strata severely compromises the microstructural integrity of osteons in Os Draconis,but Os Draconis still largely retains the structural features of mammalian bone.Methods:Using verified authentic Os Draconis samples over 10,000 years old as a baseline,this study summarizes the ultrastructural characteristics of genuine Os Draconis.Employing electron probe microanalysis and optical polarized light microscopy,we examined 28 batches of authentic Os Draconis and 31 batches of counterfeits to identify their ultrastructural differences.Key points for ultrastructural identification of Os Draconis were compiled,and a new identification approach was proposed based on these differences.Results:Authentic Os Draconis exhibited distinct ultrastructural markers:irregularly shaped osteons with traversing fissures,deformed/displaced Haversian canals,and secondary mineral infill(predominantly calcium carbonate).Counterfeits showed regular osteon arrangements,absent traversal fissures,and homogeneous hydroxyapatite composition.Lab-simulated samples lacked structural degradation features.EPMA confirmed calcium carbonate infill in fossilized Haversian canals,while elemental profiles differentiated lacunae types(void vs.mineral-packed).Conclusion:The study established ultrastructural criteria for authentic Os Draconis identification:osteon deformation,geological fissures penetrating bone units,and heterogenous mineral deposition.These features,unattainable in counterfeits or modern processed bones,provide a cost-effective,accurate identification method.This approach bridges gaps in TCM material standardization and supports quality control for clinical applications.展开更多
The transcription factor Ets1 is essential for the development of invariant natural killer T(iNKT)cells;however,its detailed role and mechanism of action are unknown.Here,we show that Ets1 is dispensable for CD1d-medi...The transcription factor Ets1 is essential for the development of invariant natural killer T(iNKT)cells;however,its detailed role and mechanism of action are unknown.Here,we show that Ets1 is dispensable for CD1d-mediated selection,but is essential for subsequent differentiation of post-selected iNKT cells.This function is partly compensated by forced expression of a transgenic Vα14 Jα18 TCR and is independent of its N-terminal Pointed(PNT)domain.Ets1 is also required for optimal expression of cytokines by differentiated iNKT1 and iNKT2 cells,but inhibits the differentiation/function of iNKT17 in vitro and in vivo.These functions,however,depend on the PNT domain.Taken together,our results indicate that Ets1 regulates the differentiation/function of iNKT cells at multiple steps through both PNT domaindependent and PNT domain-independent mechanisms.展开更多
Netizen Comments:The blackmagic oftypical Chinese parents when you share happiness with them,your happiness will disappear;when you share your troubles with them,your troubles double".Chinese parents crave absolu...Netizen Comments:The blackmagic oftypical Chinese parents when you share happiness with them,your happiness will disappear;when you share your troubles with them,your troubles double".Chinese parents crave absolute authority.Their parenting philosophy is that encouragement foments rebellion while oppression guarantees obedience"展开更多
This paper is a research on the variation character of stagnation point heat flux for hypersonic pointed bodies from continuum to rarefied flow states by using theoretical analysis and numerical simulation methods. Th...This paper is a research on the variation character of stagnation point heat flux for hypersonic pointed bodies from continuum to rarefied flow states by using theoretical analysis and numerical simulation methods. The newly developed near space hypersonic cruise vehicles have sharp noses and wingtips,which desires exact and relatively simple methods to estimate the stagnation point heat flux. With the decrease of the curvature radius of the leading edge,the flow becomes rarefied gradually,and viscous interaction effects and rarefied gas effects come forth successively,which results in that the classical Fay-Riddell equation under continuum hypothesis will become invalid and the variation of stagnation point heat flux is characterized by a new trend. The heat flux approaches the free molecular flow limit instead of an infinite value when the curvature radius of the leading edge tends to 0. The physical mechanism behind this phenomenon remains in need of theoretical study. Firstly,due to the fact that the whole flow regime can be described by Boltzmann equation,the continuum and rarefied flow are analyzed under a uniform framework. A relationship is established between the molecular collision insufficiency in rarefied flow and the failure of Fourier's heat conduction law along with the increasing significance of the nonlinear heat flux. Then based on an inspiration drew from Burnett approximation,control factors are grasped and a specific heat flux expression containing the nonlinear term is designed in the stagnation region of hypersonic leading edge. Together with flow pattern analysis,the ratio of nonlinear to linear heat flux Wr is theoretically obtained as a parameter which reflects the influence of nonlinear factors,i.e. a criterion to classify the hypersonic rarefied flows. Ultimately,based on the characteristic parameter Wr,a bridge function with physical background is constructed,which predicts comparative reasonable results in coincidence well with DSMC and experimental data in the whole flow regime.展开更多
On February 2nd Clariant announced Peter Lindner has been ap-pointed President,Asia Pacific at specialty chemicals company Clarianteffective February 1 st,2009.Peter Lindner was President of the formerSpecial Market r...On February 2nd Clariant announced Peter Lindner has been ap-pointed President,Asia Pacific at specialty chemicals company Clarianteffective February 1 st,2009.Peter Lindner was President of the formerSpecial Market region of Clariant,which comprised of Eastern Euro-pean and Middle-east countries such as Turkey,India and Pakistan.展开更多
Currently,the BeiDou⁃3(BDS⁃3)precise point positioning(PPP)service(PPP⁃B2b)mostly employs the ionosphere⁃free(IF)combination model for precise timing,which tends to amplify the noise in observation values.To address t...Currently,the BeiDou⁃3(BDS⁃3)precise point positioning(PPP)service(PPP⁃B2b)mostly employs the ionosphere⁃free(IF)combination model for precise timing,which tends to amplify the noise in observation values.To address this issue,this paper proposes a real⁃time BDS⁃3 precise unidirectional timing model based on uncombined(UC)observations using the BDS⁃3 PPP⁃B2b service.This model resolves the challenge of the amplified observation noise inherent in the IF combination model.The experiment involved selecting eight global navigation satellite system(GNSS)observation stations within China and collecting continuous observation data for 15 d.A comparative analy⁃sis with the traditional dual⁃frequency IF combination PPP timing model showed that the BDS⁃3 UC PPP timing based on the BDS⁃3 PPP⁃B2b service can achieve a timing preci⁃sion of 0.5 ns.In addition,it was found that due to global positioning system(GPS)satellite clock products in the BDS⁃3 PPP⁃B2b service not being unified to the standard time,the GPS IF PPP timing method based on the BDS⁃3 PPP⁃B2b service is not recommended for precise timing.In summary,the BDS⁃3 UC PPP timing model proposed in this paper is suitable for precise timing,providing observa⁃tion values with smaller noise,and its timing accuracy is comparable to that of the BDS⁃3 IF PPP,with slightly better frequency stability.展开更多
This paper introduces part of the content in the association standard,T/CAAM0002–2020 Nomenclature and Location of Acupuncture Points for Laboratory Animals Part 2:Rat.This standard was released by the China Associat...This paper introduces part of the content in the association standard,T/CAAM0002–2020 Nomenclature and Location of Acupuncture Points for Laboratory Animals Part 2:Rat.This standard was released by the China Association of Acupuncture and Moxibustion on May 15,2020,implemented on October 31,2020,and published by Standards Press of China.The standard was drafted by the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,and the Nanjing University of Chinese Medicine.Principal draftsmen:Xiang-hong JING and Xing-bang HUA.Participating draftsmen:Wan-Zhu BAI,Bin XU,Dong-sheng XU,Yi GUO,Tie-ming MA,Xin-jun WANG,and Sheng-feng LU.展开更多
基金Supported by the Agricultural Fund Project of Ministry of Science and Technology(Y0415)the China Agriculture Research System(Sericulture)~~
文摘[Objective] To study the cocoon traits of wild silkworm descendants. [Method] In the selective breeding of domesticated raising wild silkworm and wild silkworm descendants, investigation on the traits of the built cocoons was carried out. [Result] The pointed traits of cocoons displayed obviously in the wild silkworm descendants, its pointed parts were consistent with the rear part of silkworm chrysalis, and the female silkworm has slight difference, indicating the silkworm co- coon pointed trait was hereditary. [Conclusion] This study provided references for the study of silkworm cocoon traits of wild silkworm descendant and guides the selective breeding of silkworm variety.
文摘Computations and Experiments were performed to get an understanding of the flow field around a rectangular supersonic air intake with pointed cowl [90°] at different back pressures for Mach 2.2. The effect of Cowl shape on the ramp surface pressure distribution is discussed and compared with existing V-Notch [90°] intake model at free exit condition. It was found that using pointed cowl [90°] intake model, a better pressure recovery was achieved compared to the V-Notch [90°] intake model at Mach 2.2. Both Pointed and V-Notch intake models showed good starting characteristics. For change in back pressure, the occurence of normal shock, flow separation zone and flow reversal were observed. All experiments are performed only for the Pointed cowl [90°] intake model. All the 3-D computations were performed by using software available at B.I.T, Mesra, Ranchi.
文摘On October 26,the Ministry of Foreign Affairs of China announced the appointment of Ambassador Xu Bu as the President of China Institute of International Studies(CIIS).Zheng Zeguang,Vice Minister of Foreign Affairs,attended the appointment ceremony and expressed his hope for Ambassador Xu to unite the CIIS leadership and staff under the guidance of the Foreign Ministry and elevate the top-level think tank to a new height.
文摘There is an amazing healing power in the novel The Country of the Pointed Firs embodied in nature and the local people. Reading this novel, everyone can be the narrator who has experienced a journey of healing in Dunnet Landing during her interactions with the coastal natural sceneries and the lovely local residents in that in those small islands.
基金supported by the Startup Foundation for Introducing Talent of NUIST(Grant No.2018R039)the Natural Science Foundation of China(Grant No.11201231).
文摘We obtain a necessary condition for a strictly weakly integral generalized Tambara-Yamagami fusion category to be braided.Then we use this result to classify braided extensions of a pointed fusion category with prime dimension.
基金Supported by National Basic Research Program of China (973 Program 2009CB824800)
文摘The Hard X-ray Modulation Telescope （HXMT） is an X-ray astronomy satellite consisting of three slat-collimated instruments, the High Energy X-ray Instrument （HE）, the Medium Energy X-ray Instrument （ME）, and the Low Energy X-ray Instrument （LE）. HXMT will carry out an all sky survey and make pointed observations in the 1-250 keV energy band. In order to get the source and background fluxes simultaneously in the pointed observations, two methods, i.e., the combined field of view （FOV） method and the off-axis pointing method are proposed in this paper. Comprehensive analyses of the sensitivities of the three instruments by using these two methods are presented, respectively. It is found that the off-axis pointing method has a higher sensitivity for HE and ME but a lower sensitivity for LE. Since the axes of the three instruments are aligned along the same direction, the off-axis pointing method is recommended as the main method in the pointed observation for HXMT; the combined FOV method can be used when LE is the most relevant instrument in order to satisfy the scientific objective of the observation.
文摘In this paper we study the pointed representations of the Virasoro algebra.We show that unitary irreducible pointed representations of the Virasoro algebra are Harish-Chandra repre- sentations,thus they either are of highest or lowest weights or have all weight spaces of dimension 1.Further,we prove that unitary irreducible weight representations of Virasoro superalgebras are either of highest weights or of lowest weights,hence they are also Harish-Chandra representations.
基金supported by the Program for New Century Excellent Talents in University(Grant No.06-0504)National Natural Science Foundation of China (Grant No.10771153)
文摘Let T(G) be the Teichmüller space of a Fuchsian group G and T(G) be the pointed Teichmüller space of a corresponding pointed Fuchsian group G.We will discuss the existence of holomorphic sections of the projection from the space M(G) of Beltrami coefficients for G to T(G) and of that from T(G) to T(G) as well.We will also study the biholomorphic isomorphisms between two pointed Teichmüller spaces.
文摘We focus on the classification of pointed p^3-dimensional Hopf algebras H over any algebraically closed field of prime characteristic p 〉 0. In particular, we consider certain cases when the group of grouplike elements is of order p or p^2 that is, when H is pointed but is not connected nor a group algebra. The structures of the associated graded algebra gr H are completely described as bosonizations of graded braided Hopf algebras over group algebras, and most of the lifting structures of H are given. This work provides many new examples of （parametrized） non-commutative, non-cocommutative finite- dimensional Hopf algebras in positive characteristic.
文摘A contravaried bilinear pairing X on every M(ρ) × M(ρθ) is determined and it is provedthat M(ρ)is irreducible if and only if K is left nondegellerate. It is also proved that every cyclicpointed module is a quotient of some Verma-like poillted module; moreover if it is irreduciblethen it is a quotieDt of the Vermarlike poiDted module by the left kernel of some bilinearpairing K. In case the mass fUnction is symmetric, there exists a bilinear form on M(ρ). It isproved that unitals pointed modules are integrable. In addition, a characterization of the massfunctions of Kac-Moody algebras is given, which is a generalization of the finite dimensionalLie algebras case.
基金supported by STI 2030-Major Projects,No.2021ZD0201603(to JL)the Joint Foundation Program of the Chinese Academy of Sciences,No.8091A170201(to JL)+1 种基金the National Natural Science Foundation of China,Nos.T2293730(to XC),T2293731(to XC),T2293734(to XC),62471291(to YW),62121003(to XC),61960206012(to XC),62333020(to XC),and 62171434(to XC)the National Key Research and Development Program of China,Nos.2022YFC2402501(to XC),2022YFB3205602(to XC).
文摘Neuromodulation techniques effectively intervene in cognitive function,holding considerable scientific and practical value in fields such as aerospace,medicine,life sciences,and brain research.These techniques utilize electrical stimulation to directly or indirectly target specific brain regions,modulating neural activity and influencing broader brain networks,thereby regulating cognitive function.Regulating cognitive function involves an understanding of aspects such as perception,learning and memory,attention,spatial cognition,and physical function.To enhance the application of cognitive regulation in the general population,this paper reviews recent publications from the Web of Science to assess the advancements and challenges of invasive and non-invasive stimulation methods in modulating cognitive functions.This review covers various neuromodulation techniques for cognitive intervention,including deep brain stimulation,vagus nerve stimulation,and invasive methods using microelectrode arrays.The non-invasive techniques discussed include transcranial magnetic stimulation,transcranial direct current stimulation,transcranial alternating current stimulation,transcutaneous electrical acupoint stimulation,and time interference stimulation for activating deep targets.Invasive stimulation methods,which are ideal for studying the pathogenesis of neurological diseases,tend to cause greater trauma and have been less researched in the context of cognitive function regulation.Non-invasive methods,particularly newer transcranial stimulation techniques,are gentler and more appropriate for regulating cognitive functions in the general population.These include transcutaneous acupoint electrical stimulation using acupoints and time interference methods for activating deep targets.This paper also discusses current technical challenges and potential future breakthroughs in neuromodulation technology.It is recommended that neuromodulation techniques be combined with neural detection methods to better assess their effects and improve the accuracy of non-invasive neuromodulation.Additionally,researching closed-loop feedback neuromodulation methods is identified as a promising direction for future development.
基金supported by the Scientific and Technological Innovation Project of the China Academy of Chinese Medical Sciences(CI2021A04013)the National Natural Science Foundation of China(82204610)+1 种基金the Qihang Talent Program(L2022046)the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ15-YQ-041 and L2021029).
文摘Background:The medicinal material known as Os Draconis(Longgu)originates from fossilized remains of ancient mammals and is widely used in treating emotional and mental conditions.However,fossil resources are nonrenewable,and clinical demand is increasingly difficult to meet,leading to a proliferation of counterfeit products.During prolonged geological burial,static pressure from the surrounding strata severely compromises the microstructural integrity of osteons in Os Draconis,but Os Draconis still largely retains the structural features of mammalian bone.Methods:Using verified authentic Os Draconis samples over 10,000 years old as a baseline,this study summarizes the ultrastructural characteristics of genuine Os Draconis.Employing electron probe microanalysis and optical polarized light microscopy,we examined 28 batches of authentic Os Draconis and 31 batches of counterfeits to identify their ultrastructural differences.Key points for ultrastructural identification of Os Draconis were compiled,and a new identification approach was proposed based on these differences.Results:Authentic Os Draconis exhibited distinct ultrastructural markers:irregularly shaped osteons with traversing fissures,deformed/displaced Haversian canals,and secondary mineral infill(predominantly calcium carbonate).Counterfeits showed regular osteon arrangements,absent traversal fissures,and homogeneous hydroxyapatite composition.Lab-simulated samples lacked structural degradation features.EPMA confirmed calcium carbonate infill in fossilized Haversian canals,while elemental profiles differentiated lacunae types(void vs.mineral-packed).Conclusion:The study established ultrastructural criteria for authentic Os Draconis identification:osteon deformation,geological fissures penetrating bone units,and heterogenous mineral deposition.These features,unattainable in counterfeits or modern processed bones,provide a cost-effective,accurate identification method.This approach bridges gaps in TCM material standardization and supports quality control for clinical applications.
基金supported by grants from the United States Department of Defense(W81XWH-11-1-0492 to I.-C.H.)the National Institutes of Health(AR070171 to I.-C.H.and HL082717 to P.O.)+1 种基金the Ministry of Science and Technology(103-2311-B-650-001 and 105-2311-B-214-002 to T.-S.T.),TaiwanEDa Hospital(103-EDN16,104-EDN12,105-EDN07,and EDAHI105002 to T.-S.T.),Taiwan.
文摘The transcription factor Ets1 is essential for the development of invariant natural killer T(iNKT)cells;however,its detailed role and mechanism of action are unknown.Here,we show that Ets1 is dispensable for CD1d-mediated selection,but is essential for subsequent differentiation of post-selected iNKT cells.This function is partly compensated by forced expression of a transgenic Vα14 Jα18 TCR and is independent of its N-terminal Pointed(PNT)domain.Ets1 is also required for optimal expression of cytokines by differentiated iNKT1 and iNKT2 cells,but inhibits the differentiation/function of iNKT17 in vitro and in vivo.These functions,however,depend on the PNT domain.Taken together,our results indicate that Ets1 regulates the differentiation/function of iNKT cells at multiple steps through both PNT domaindependent and PNT domain-independent mechanisms.
文摘Netizen Comments:The blackmagic oftypical Chinese parents when you share happiness with them,your happiness will disappear;when you share your troubles with them,your troubles double".Chinese parents crave absolute authority.Their parenting philosophy is that encouragement foments rebellion while oppression guarantees obedience"
基金Supported by the National Natural Science Foundation of China (Grant No. 90716011)
文摘This paper is a research on the variation character of stagnation point heat flux for hypersonic pointed bodies from continuum to rarefied flow states by using theoretical analysis and numerical simulation methods. The newly developed near space hypersonic cruise vehicles have sharp noses and wingtips,which desires exact and relatively simple methods to estimate the stagnation point heat flux. With the decrease of the curvature radius of the leading edge,the flow becomes rarefied gradually,and viscous interaction effects and rarefied gas effects come forth successively,which results in that the classical Fay-Riddell equation under continuum hypothesis will become invalid and the variation of stagnation point heat flux is characterized by a new trend. The heat flux approaches the free molecular flow limit instead of an infinite value when the curvature radius of the leading edge tends to 0. The physical mechanism behind this phenomenon remains in need of theoretical study. Firstly,due to the fact that the whole flow regime can be described by Boltzmann equation,the continuum and rarefied flow are analyzed under a uniform framework. A relationship is established between the molecular collision insufficiency in rarefied flow and the failure of Fourier's heat conduction law along with the increasing significance of the nonlinear heat flux. Then based on an inspiration drew from Burnett approximation,control factors are grasped and a specific heat flux expression containing the nonlinear term is designed in the stagnation region of hypersonic leading edge. Together with flow pattern analysis,the ratio of nonlinear to linear heat flux Wr is theoretically obtained as a parameter which reflects the influence of nonlinear factors,i.e. a criterion to classify the hypersonic rarefied flows. Ultimately,based on the characteristic parameter Wr,a bridge function with physical background is constructed,which predicts comparative reasonable results in coincidence well with DSMC and experimental data in the whole flow regime.
文摘On February 2nd Clariant announced Peter Lindner has been ap-pointed President,Asia Pacific at specialty chemicals company Clarianteffective February 1 st,2009.Peter Lindner was President of the formerSpecial Market region of Clariant,which comprised of Eastern Euro-pean and Middle-east countries such as Turkey,India and Pakistan.
基金The Basic Science Center Project of the National Natural Science Foundation of China(No.42388102)the Jiangsu Province Natural Resources Science and Technology Project(No.JSZRKJ202404).
文摘Currently,the BeiDou⁃3(BDS⁃3)precise point positioning(PPP)service(PPP⁃B2b)mostly employs the ionosphere⁃free(IF)combination model for precise timing,which tends to amplify the noise in observation values.To address this issue,this paper proposes a real⁃time BDS⁃3 precise unidirectional timing model based on uncombined(UC)observations using the BDS⁃3 PPP⁃B2b service.This model resolves the challenge of the amplified observation noise inherent in the IF combination model.The experiment involved selecting eight global navigation satellite system(GNSS)observation stations within China and collecting continuous observation data for 15 d.A comparative analy⁃sis with the traditional dual⁃frequency IF combination PPP timing model showed that the BDS⁃3 UC PPP timing based on the BDS⁃3 PPP⁃B2b service can achieve a timing preci⁃sion of 0.5 ns.In addition,it was found that due to global positioning system(GPS)satellite clock products in the BDS⁃3 PPP⁃B2b service not being unified to the standard time,the GPS IF PPP timing method based on the BDS⁃3 PPP⁃B2b service is not recommended for precise timing.In summary,the BDS⁃3 UC PPP timing model proposed in this paper is suitable for precise timing,providing observa⁃tion values with smaller noise,and its timing accuracy is comparable to that of the BDS⁃3 IF PPP,with slightly better frequency stability.
文摘This paper introduces part of the content in the association standard,T/CAAM0002–2020 Nomenclature and Location of Acupuncture Points for Laboratory Animals Part 2:Rat.This standard was released by the China Association of Acupuncture and Moxibustion on May 15,2020,implemented on October 31,2020,and published by Standards Press of China.The standard was drafted by the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,and the Nanjing University of Chinese Medicine.Principal draftsmen:Xiang-hong JING and Xing-bang HUA.Participating draftsmen:Wan-Zhu BAI,Bin XU,Dong-sheng XU,Yi GUO,Tie-ming MA,Xin-jun WANG,and Sheng-feng LU.
