Myopia is not only a serious problem in Hong Kong, but is a rising global phenomena. It is predicted that by 2050, 49.8% of the world’s population will have myopia with approximately 900 million people developing hig...Myopia is not only a serious problem in Hong Kong, but is a rising global phenomena. It is predicted that by 2050, 49.8% of the world’s population will have myopia with approximately 900 million people developing high myopia. High myopia is associated with the development of staphyloma, lacquer cracks and myopic macular degeneration, and is a leading cause of profound blindness. Understanding how high myopia develops and its relationship to myopia susceptibility is critical for the development of appropriate treatments. Animal models have provided insight into the possible underlying mechanisms, and are useful for testing potential treatment options. We have developed a mammalian model of myopia using the guinea pig in which eye growth is manipulated though classical aberrant visual input. This talk will review some of the major insights gained from such models and present new data on the anatomical and optical changes associated with the progression of myopia. This includes the effect of blur exposure on the optical development of the eye, the transition between myopia and high myopia development, and the potential impact of scleral treatments for high myopia.展开更多
Developing approaches for precise engineering of the optical response of plasmonic nanocavities at the postfabrication stage is important for achieving enhanced and tunable light-matter interactions.In this work,we de...Developing approaches for precise engineering of the optical response of plasmonic nanocavities at the postfabrication stage is important for achieving enhanced and tunable light-matter interactions.In this work,we demonstrate selective enhancement/suppression of specific plasmonic modes by embedding nanocube-on-mirror plasmonic nanocavities into a poly(methyl methacrylate)(PMMA)layer with a controllable thickness.With the increase of the PMMA thickness from 0 to approximately 100 nm,the dominating out-of-plane plasmonic modes are significantly suppressed in the scattering spectra,while the in-plane plasmonic modes are greatly enhanced with a factor reaching 102±20.This enhancement is related to the variation of momentum matching between the plasmonic modes and the radiative fields,affecting both mode excitation and emission properties.In addition,the spectral positions of the in-plane and out-of-plane plasmonic modes shift up to 52±5 and 81±2 nm,respectively.These properties are important for matching and enhancing plasmonic and molecular resonances in a variety of applications.展开更多
A non-halogen highly flame-retardant 0.9mm optical fiber and 2.0mm simplex optical cord, which are harmonized with the ecosystem, have been developed. The characteristics of them are presented in this paper.
文摘Myopia is not only a serious problem in Hong Kong, but is a rising global phenomena. It is predicted that by 2050, 49.8% of the world’s population will have myopia with approximately 900 million people developing high myopia. High myopia is associated with the development of staphyloma, lacquer cracks and myopic macular degeneration, and is a leading cause of profound blindness. Understanding how high myopia develops and its relationship to myopia susceptibility is critical for the development of appropriate treatments. Animal models have provided insight into the possible underlying mechanisms, and are useful for testing potential treatment options. We have developed a mammalian model of myopia using the guinea pig in which eye growth is manipulated though classical aberrant visual input. This talk will review some of the major insights gained from such models and present new data on the anatomical and optical changes associated with the progression of myopia. This includes the effect of blur exposure on the optical development of the eye, the transition between myopia and high myopia development, and the potential impact of scleral treatments for high myopia.
基金National Key Research and Development Program of China(2023YFB2806701)National Natural Science Foundation of China(92250305,62305293)+2 种基金Natural Science Foundation of Zhejiang Province(LR25F050001,LDT23F04015F05)Engineering and Physical Sciences Research Council(EP/W017075/1)New Cornerstone Science Foundation(NCI202216)。
文摘Developing approaches for precise engineering of the optical response of plasmonic nanocavities at the postfabrication stage is important for achieving enhanced and tunable light-matter interactions.In this work,we demonstrate selective enhancement/suppression of specific plasmonic modes by embedding nanocube-on-mirror plasmonic nanocavities into a poly(methyl methacrylate)(PMMA)layer with a controllable thickness.With the increase of the PMMA thickness from 0 to approximately 100 nm,the dominating out-of-plane plasmonic modes are significantly suppressed in the scattering spectra,while the in-plane plasmonic modes are greatly enhanced with a factor reaching 102±20.This enhancement is related to the variation of momentum matching between the plasmonic modes and the radiative fields,affecting both mode excitation and emission properties.In addition,the spectral positions of the in-plane and out-of-plane plasmonic modes shift up to 52±5 and 81±2 nm,respectively.These properties are important for matching and enhancing plasmonic and molecular resonances in a variety of applications.
文摘A non-halogen highly flame-retardant 0.9mm optical fiber and 2.0mm simplex optical cord, which are harmonized with the ecosystem, have been developed. The characteristics of them are presented in this paper.
