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Elastic Multiple Kernel Learning 被引量:6
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作者 WU Zheng-Peng ZHANG Xue-Gong 《自动化学报》 EI CSCD 北大核心 2011年第6期693-699,共7页
(MKL ) 多重核学习被建议处理核熔化。MKL 听说线性联合几个核并且解决同时与联合的核联系的支持的向量机器(SVM ) 。MKL 的当前的框架鼓励核联合系数的稀少。核的重要部分什么时候是增进知识的,强迫稀少,趋于选择仅仅一些核并且可以... (MKL ) 多重核学习被建议处理核熔化。MKL 听说线性联合几个核并且解决同时与联合的核联系的支持的向量机器(SVM ) 。MKL 的当前的框架鼓励核联合系数的稀少。核的重要部分什么时候是增进知识的,强迫稀少,趋于选择仅仅一些核并且可以忽略有用信息。在这份报纸,我们建议学习的有弹性的多重核(EMKL ) 完成适应的核熔化。EMKL 使用混合规则化功能损害稀少和非稀少。MKL 和 SVM 能被认为是 EMKL 的特殊情况。为 MKL 问题基于坡度降下算法,我们建议一个快算法解决 EMKL 问题。模拟数据集上的结果证明 EMKL 的表演有利地比作 MKL 和 SVM。我们进一步把 EMKL 用于基因集合分析并且得到有希望的结果。最后,我们学习比作另外的非稀少的 MKL 的 EMKL 的理论优点。 展开更多
关键词 《自动化学报》 期刊 摘要 编辑部
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Incremental support vector machine algorithm based on multi-kernel learning 被引量:7
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作者 Zhiyu Li Junfeng Zhang Shousong Hu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2011年第4期702-706,共5页
A new incremental support vector machine (SVM) algorithm is proposed which is based on multiple kernel learning. Through introducing multiple kernel learning into the SVM incremental learning, large scale data set l... A new incremental support vector machine (SVM) algorithm is proposed which is based on multiple kernel learning. Through introducing multiple kernel learning into the SVM incremental learning, large scale data set learning problem can be solved effectively. Furthermore, different punishments are adopted in allusion to the training subset and the acquired support vectors, which may help to improve the performance of SVM. Simulation results indicate that the proposed algorithm can not only solve the model selection problem in SVM incremental learning, but also improve the classification or prediction precision. 展开更多
关键词 support vector machine (SVM) incremental learning multiple kernel learning (MKL).
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Convergence analysis for complementary-label learning with kernel ridge regression
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作者 NIE Wei-lin WANG Cheng XIE Zhong-hua 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第3期533-544,共12页
Complementary-label learning(CLL)aims at finding a classifier via samples with complementary labels.Such data is considered to contain less information than ordinary-label samples.The transition matrix between the tru... Complementary-label learning(CLL)aims at finding a classifier via samples with complementary labels.Such data is considered to contain less information than ordinary-label samples.The transition matrix between the true label and the complementary label,and some loss functions have been developed to handle this problem.In this paper,we show that CLL can be transformed into ordinary classification under some mild conditions,which indicates that the complementary labels can supply enough information in most cases.As an example,an extensive misclassification error analysis was performed for the Kernel Ridge Regression(KRR)method applied to multiple complementary-label learning(MCLL),which demonstrates its superior performance compared to existing approaches. 展开更多
关键词 multiple complementary-label learning partial label learning error analysis reproducing kernel Hilbert spaces
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Short-term Wind Power Prediction Based on Soft Margin Multiple Kernel Learning Method 被引量:2
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作者 Jun Li Liancai Ma 《Chinese Journal of Electrical Engineering》 CSCD 2022年第1期70-80,共11页
For short-term wind power prediction,a soft margin multiple kernel learning(MKL)method is proposed.In order to improve the predictive effect of the MKL method for wind power,a kernel slack variable is introduced into ... For short-term wind power prediction,a soft margin multiple kernel learning(MKL)method is proposed.In order to improve the predictive effect of the MKL method for wind power,a kernel slack variable is introduced into each base kernel to solve the objective function.Two kinds of soft margin MKL methods based on hinge loss function and square hinge loss function can be obtained when hinge loss functions and square hinge loss functions are selected.The improved methods demonstrate good robustness and avoid the disadvantage of the hard margin MKL method which only selects a few base kernels and discards other useful kernels when solving the objective function,thereby achieving an effective yet sparse solution for the MKL method.In order to verify the effectiveness of the proposed method,the soft margin MKL method was applied to the second wind farm of Tianfeng from Xinjiang for short-term wind power single-step prediction,and the single-step and multi-step predictions of short-term wind power was also carried out using measured data provided by alberta electric system operator(AESO).Compared with the support vector machine(SVM),extreme learning machine(ELM),kernel based extreme learning machine(KELM)methods as well as the SimpleMKL method under the same conditions,the experimental results demonstrate that the soft margin MKL method with different loss functions can efficiently achieve higher prediction accuracy and good generalization performance for short-term wind power prediction,which confirms the effectiveness of the method. 展开更多
关键词 Soft margin slack variable loss function multiple kernel learning wind power prediction
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EEG-based Emotion Recognition Using Multiple Kernel Learning 被引量:1
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作者 Qian Cai Guo-Chong Cui Hai-Xian Wang 《Machine Intelligence Research》 EI CSCD 2022年第5期472-484,共13页
Emotion recognition based on electroencephalography(EEG)has a wide range of applications and has great potential value,so it has received increasing attention from academia and industry in recent years.Meanwhile,multi... Emotion recognition based on electroencephalography(EEG)has a wide range of applications and has great potential value,so it has received increasing attention from academia and industry in recent years.Meanwhile,multiple kernel learning(MKL)has also been favored by researchers for its data-driven convenience and high accuracy.However,there is little research on MKL in EEG-based emotion recognition.Therefore,this paper is dedicated to exploring the application of MKL methods in the field of EEG emotion recognition and promoting the application of MKL methods in EEG emotion recognition.Thus,we proposed a support vector machine(SVM)classifier based on the MKL algorithm EasyMKL to investigate the feasibility of MKL algorithms in EEG-based emotion recognition problems.We designed two data partition methods,random division to verify the validity of the MKL method and sequential division to simulate practical applications.Then,tri-categorization experiments were performed for neutral,negative and positive emotions based on a commonly used dataset,the Shanghai Jiao Tong University emotional EEG dataset(SEED).The average classification accuracies for random division and sequential division were 92.25%and 74.37%,respectively,which shows better classification performance than the traditional single kernel SVM.The final results show that the MKL method is obviously effective,and the application of MKL in EEG emotion recognition is worthy of further study.Through the analysis of the experimental results,we discovered that the simple mathematical operations of the features on the symmetrical electrodes could not effectively integrate the spatial information of the EEG signals to obtain better performance.It is also confirmed that higher frequency band information is more correlated with emotional state and contributes more to emotion recognition.In summary,this paper explores research on MKL methods in the field of EEG emotion recognition and provides a new way of thinking for EEG-based emotion recognition research. 展开更多
关键词 Emotion recognition electroencephalography(EEG) multiple kernel learning machine learning brain computer interface
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Identification of human microRNA-disease association via low-rank approximation-based link propagation and multiple kernel learning 被引量:1
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作者 Yizheng WANG Xin ZHANG +5 位作者 Ying JU Qing LIU Quan ZOU Yazhou ZHANG Yijie DING Ying ZHANG 《Frontiers of Computer Science》 SCIE EI CSCD 2024年第2期217-229,共13页
Numerous studies have demonstrated that human microRNAs(miRNAs)and diseases are associated and studies on the microRNA-disease association(MDA)have been conducted.We developed a model using a low-rank approximation-ba... Numerous studies have demonstrated that human microRNAs(miRNAs)and diseases are associated and studies on the microRNA-disease association(MDA)have been conducted.We developed a model using a low-rank approximation-based link propagation algorithm with Hilbert–Schmidt independence criterion-based multiple kernel learning(HSIC-MKL)to solve the problem of the large time commitment and cost of traditional biological experiments involving miRNAs and diseases,and improve the model effect.We constructed three kernels in miRNA and disease space and conducted kernel fusion using HSIC-MKL.Link propagation uses matrix factorization and matrix approximation to effectively reduce computation and time costs.The results of the experiment show that the approach we proposed has a good effect,and,in some respects,exceeds what existing models can do. 展开更多
关键词 human miRNA-disease association multiple kernel learning link propagation miRNA similarity disease similarity
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Noisy speech emotion recognition using sample reconstruction and multiple-kernel learning 被引量:1
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作者 Jiang Xiaoqing Xia Kewen +1 位作者 Lin Yongliang Bai Jianchuan 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 2017年第2期1-9,17,共10页
Speech emotion recognition (SER) in noisy environment is a vital issue in artificial intelligence (AI). In this paper, the reconstruction of speech samples removes the added noise. Acoustic features extracted from... Speech emotion recognition (SER) in noisy environment is a vital issue in artificial intelligence (AI). In this paper, the reconstruction of speech samples removes the added noise. Acoustic features extracted from the reconstructed samples are selected to build an optimal feature subset with better emotional recognizability. A multiple-kernel (MK) support vector machine (SVM) classifier solved by semi-definite programming (SDP) is adopted in SER procedure. The proposed method in this paper is demonstrated on Berlin Database of Emotional Speech. Recognition accuracies of the original, noisy, and reconstructed samples classified by both single-kernel (SK) and MK classifiers are compared and analyzed. The experimental results show that the proposed method is effective and robust when noise exists. 展开更多
关键词 speech emotion recognition compressed sensing multiple-kernel learning feature selection
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An assessment of surrogate fuel using Bayesian multiple kernel learning model in sight of sooting tendency
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作者 Lei ZHU Zhan GAO +2 位作者 Xiaogang CHENG Fei REN Zhen HUANG 《Frontiers in Energy》 SCIE CSCD 2022年第2期277-291,共15页
An integrated and systematic database of sooting tendency with more than 190 kinds of fuels was obtained through a series of experimental investigations. The laser-induced incandescence (LII) method was used to acquir... An integrated and systematic database of sooting tendency with more than 190 kinds of fuels was obtained through a series of experimental investigations. The laser-induced incandescence (LII) method was used to acquire the 2D distribution of soot volume fraction, and an apparatus-independent yield sooting index (YSI) was experimentally obtained. Based on the database, a novel predicting model of YSI values for surrogate fuels was proposed with the application of a machine learning method, named the Bayesian multiple kernel learning (BMKL) model. A high correlation coefficient (0.986) between measured YSIs and predicted values with the BMKL model was obtained, indicating that the BMKL model had a reliable and accurate predictive capacity for YSI values of surrogate fuels. The BMKL model provides an accurate and low-cost approach to assess surrogate performances of diesel, jet fuel, and biodiesel in terms of sooting tendency. Particularly, this model is one of the first attempts to predict the sooting tendencies of surrogate fuels that concurrently contain hydrocarbon and oxygenated components and shows a satisfying matching level. During surrogate formulation, the BMKL model can be used to shrink the surrogate candidate list in terms of sooting tendency and ensure the optimal surrogate has a satisfying matching level of soot behaviors. Due to the high accuracy and resolution of YSI prediction, the BMKL model is also capable of providing distinguishing information of sooting tendency for surrogate design. 展开更多
关键词 sooting tendency yield sooting index Bayesian multiple kernel learning surrogate assessment surrogate formulation
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基于无监督迁移学习的动车组轴承故障诊断算法
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作者 尹金豪 张宁 +3 位作者 张瑞芳 张春 焦静 刘志杰 《铁道机车车辆》 北大核心 2026年第1期39-47,共9页
为解决动车组轴承故障诊断模型在不同工况下准确率下降的问题,提出了一种基于无监督迁移学习的故障诊断方法。首先通过引入二次卷积神经网络改进特征提取器中ResNet网络结构,提升特征提取能力;其次采用多核最大均值差异损失和关联对齐... 为解决动车组轴承故障诊断模型在不同工况下准确率下降的问题,提出了一种基于无监督迁移学习的故障诊断方法。首先通过引入二次卷积神经网络改进特征提取器中ResNet网络结构,提升特征提取能力;其次采用多核最大均值差异损失和关联对齐距离损失缩小源域与目标域的数据分布差异,加入簇中心损失函数增强类内聚;最后通过对抗训练的方式,获得具有域不变特征的模型。基于凯斯西储大学轴承数据的试验结果表明,该方法训练的模型能够更加准确地识别不同工况下的故障类型。 展开更多
关键词 轴承 迁移学习 二次卷积神经网络 多核最大均值差异 关联对齐距离 簇中心损失
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求解多核学习的自适应随机递归梯度下降法 被引量:1
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作者 王梅 任怡果 +1 位作者 刘勇 王志宝 《计算机技术与发展》 2025年第7期93-99,共7页
针对随机递归梯度法(SARAH)求解多核学习(MKL)的不足之处,如收敛速度缓慢以及计算成本高等问题,该文提出一种改进算法——基于随机Polyak步长(SPS)的小批量随机递归梯度下降算法(SPS-MSARAH)来求解多核学习优化问题。首先将小批量方法... 针对随机递归梯度法(SARAH)求解多核学习(MKL)的不足之处,如收敛速度缓慢以及计算成本高等问题,该文提出一种改进算法——基于随机Polyak步长(SPS)的小批量随机递归梯度下降算法(SPS-MSARAH)来求解多核学习优化问题。首先将小批量方法引入随机方差缩减类算法中,选取一个固定大小的样本集代替单个训练样本计算SARAH的梯度,降低传统随机梯度下降算法使用单个样本计算梯度导致较大的波动和不稳定性所带来的方差。在此基础上,使用随机Polyak步长自适应地更新小批量SARAH的步长,使得优化过程更加灵活和鲁棒,从而解决随机优化算法中步长选取的难题。为了验证该算法的有效性,在标准数据集上进行了详细的数值实验。实验结果显示,在求解大规模多核学习优化问题时,SPS-MSARAH算法不仅显著提高了收敛速度,还有效降低了计算复杂度。此外,对初始参数的敏感性问题也得到了很好的克服,展现出良好的鲁棒性。 展开更多
关键词 多核学习 随机递归梯度下降法 随机Polyak步长 小批量 凸优化
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基于IEO-MKELM模型的重整产品辛烷值软测量方法
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作者 陈晓彦 赵超 +2 位作者 付斌 李卫东 范克威 《石油与天然气化工》 北大核心 2025年第4期131-139,共9页
目的针对催化重整产品辛烷值测量实时性较差的问题,提出基于改进平衡优化器算法的多核极限学习机(IEOMKELM)辛烷值软测量模型。方法采用混沌映射、反向学习策略、优化非线性因子、莱维飞行和贪心选择策略优化基础平衡算法,获得具有更高... 目的针对催化重整产品辛烷值测量实时性较差的问题,提出基于改进平衡优化器算法的多核极限学习机(IEOMKELM)辛烷值软测量模型。方法采用混沌映射、反向学习策略、优化非线性因子、莱维飞行和贪心选择策略优化基础平衡算法,获得具有更高全局和局部搜索能力的改进平衡算法(IEO)。随后将这一改进后的平衡优化算法应用于多核极限学习机(MKELM)多项参数的优化,进而建立了催化重整产品辛烷值软测量模型。结果利用某炼化企业的实测数据对模型精度进行验证,结果表明,由IEO-MKELM模型得到的预测值与实测值间的误差在10^(−3)数量级以下,与其他同类模型相比,IEO-MKELM模型具有更高的预测精度。结论基于IEO-MKELM的辛烷值软测量方法研究对于提高催化重整生产过程的自动化水平具有重要意义。 展开更多
关键词 IEO-MKELM 平衡优化算法 多核极限学习机 辛烷值 软测量 预测模型
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基于多隐层极限学习机的产品质量预测方法 被引量:1
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作者 丁鹏程 战洪飞 +2 位作者 林颖俊 余军合 王瑞 《计算机集成制造系统》 北大核心 2025年第11期4130-4143,共14页
在产品生产过程中,准确快速地预测产品质量有助于企业及时调整制造工艺,降低损失。针对实际生产过程中,现场采集的工艺数据存在维度高、相关性复杂且用传统方法难以准确预测的问题,提出一种基于改进多隐层极限学习机(LCGWO-DMKEA-BLSTM... 在产品生产过程中,准确快速地预测产品质量有助于企业及时调整制造工艺,降低损失。针对实际生产过程中,现场采集的工艺数据存在维度高、相关性复杂且用传统方法难以准确预测的问题,提出一种基于改进多隐层极限学习机(LCGWO-DMKEA-BLSTM)的方法。首先,通过互信息法(MI)对采集的生产工艺特征参数进行筛选,组成模型输入初始特征集。其次,将高斯核函数与反余弦核函数加权结合,构造出新的混合核函数,并引入自动编码器对极限学习机进行改进,建立深度多内核极限学习机自编码器(DMKEA)特征挖掘模型,从高维复杂工艺特征集中提取最能反映产品质量的关键特征信息,输入决策层双向长短时神经网络(BLSTM)中进行质量预测。在DMKEA学习训练中,采用基于Circle混沌映射和Levy飞行策略改进的灰狼算法(LCGWO),优化惩罚系数、核参数以及核函数组合权重,提高DMKEA的特征挖掘能力。最后用半导体薄膜晶体管液晶显示器生产线的工艺数据实验验证了所提方法的有效性。研究成果有助于企业实现准确地产品质量预测,也为企业生产的数据赋能提供参考。 展开更多
关键词 质量预测 互信息法 改进多隐层极限学习机 混合核函数 双向长短时神经网络 Circle混沌映射 Levy飞行 改进灰狼算法
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基于多核学习算法的潜在域无监督域自适应 被引量:1
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作者 姜磊 章小卫 《计算机应用与软件》 北大核心 2025年第2期314-322,共9页
为了提升无监督域自适应性能,提出一种基于多核学习算法的潜在域无监督域自适应方法。提出三个潜在域发现准则:单个潜在目标域中数据紧致性和显著性的最大化,以及潜在目标域到源域的总散度最小化。将学习到的潜在特征空间上的投影源域... 为了提升无监督域自适应性能,提出一种基于多核学习算法的潜在域无监督域自适应方法。提出三个潜在域发现准则:单个潜在目标域中数据紧致性和显著性的最大化,以及潜在目标域到源域的总散度最小化。将学习到的潜在特征空间上的投影源域数据视为源域的不同视图,缩小源域和特定潜在目标域之间的差异。在不同的视觉识别任务上的实验结果表明,该算法具有更好的分类精度与鲁棒性。 展开更多
关键词 无监督 域自适应 多核学习 潜在域
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Learning multi-kernel multi-view canonical correlations for image recognition 被引量:1
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作者 Yun-Hao Yuan Yun Li +4 位作者 Jianjun Liu Chao-Feng Li Xiao-Bo Shen Guoqing Zhang Quan-Sen Sun 《Computational Visual Media》 2016年第2期153-162,共10页
In this paper, we propose a multi-kernel multi-view canonical correlations(M2CCs) framework for subspace learning. In the proposed framework,the input data of each original view are mapped into multiple higher dimensi... In this paper, we propose a multi-kernel multi-view canonical correlations(M2CCs) framework for subspace learning. In the proposed framework,the input data of each original view are mapped into multiple higher dimensional feature spaces by multiple nonlinear mappings determined by different kernels. This makes M2 CC can discover multiple kinds of useful information of each original view in the feature spaces. With the framework, we further provide a specific multi-view feature learning method based on direct summation kernel strategy and its regularized version. The experimental results in visual recognition tasks demonstrate the effectiveness and robustness of the proposed method. 展开更多
关键词 image recognition CANONICAL CORRELATION multiple kernel learning MULTI-VIEW data FEATURE learning
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基于GASF-BMKELM的滚动轴承故障诊断方法
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作者 杨锡发 王林军 +3 位作者 邹腾枭 吴振雄 李响 陈保家 《三峡大学学报(自然科学版)》 北大核心 2025年第4期96-103,共8页
针对传统故障诊断方法难以充分提取故障信息以及神经网络依赖初始参数选择的问题,提出一种基于格拉姆角和场(Gramian angular summation field,GASF)与贝叶斯优化多核极限学习机(Bayesian optimization multi-kernel extreme learning m... 针对传统故障诊断方法难以充分提取故障信息以及神经网络依赖初始参数选择的问题,提出一种基于格拉姆角和场(Gramian angular summation field,GASF)与贝叶斯优化多核极限学习机(Bayesian optimization multi-kernel extreme learning machine,BMKELM)的故障诊断方法.首先,应用小波包节点对数能量与格拉姆角和场(GASF)将原始振动信号变换为小波包对数能量图特征;其次,使用多项式核函数与径向基核函数加权组合构建多核极限学习机(multi-kernel extreme learning machine,MKELM),同时,利用贝叶斯优化算法优化多核极限学习机的参数来提升诊断模型的故障识别能力;最后,以小波包对数能量图特征作为输入,再使用BMKELM模型完成故障特征识别与分类.通过两个数据集进行验证分析,实验结果表明,所提方法的准确率分别为99.39%和98.89%,具有较高的故障识别率和稳定性. 展开更多
关键词 滚动轴承 格拉姆角和场 小波包对数能量图 多核极限学习机 贝叶斯优化算法 故障诊断
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A stacked multiple kernel support vector machine for blast induced flyrock prediction 被引量:1
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作者 Ruixuan Zhang Yuefeng Li +2 位作者 Yilin Gui Danial Jahed Armaghani Mojtaba Yari 《Geohazard Mechanics》 2024年第1期37-48,共12页
As a widely used rock excavation method in civil and mining construction works, the blasting operations and theinduced side effects are always investigated by the existing studies. The occurrence of flyrock is regarde... As a widely used rock excavation method in civil and mining construction works, the blasting operations and theinduced side effects are always investigated by the existing studies. The occurrence of flyrock is regarded as one ofthe most important issues induced by blasting operations, since the accurate prediction of which is crucial fordelineating safety zone. For this purpose, this study developed a flyrock prediction model based on 234 sets ofblasting data collected from Sugun Copper Mine site. A stacked multiple kernel support vector machine (stackedMK-SVM) model was proposed for flyrock prediction. The proposed stacked structure can effectively improve themodel performance by addressing the importance level of different features. For comparison purpose, 6 othermachine learning models were developed, including SVM, MK-SVM, Lagragian Twin SVM (LTSVM), ArtificialNeural Network (ANN), Random Forest (RF) and M5 Tree. This study implemented a 5-fold cross validationprocess for hyperparameters tuning purpose. According to the evaluation results, the proposed stacked MK-SVMmodel achieved the best overall performance, with RMSE of 1.73 and 1.74, MAE of 0.58 and 1.08, VAF of 98.95and 99.25 in training and testing phase, respectively. 展开更多
关键词 multiple kernel learning Support vector machine Stacked model Flyrock prediction
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基于多核学习和图卷积网络的药物-疾病关联预测
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作者 陈书新 李玉田 王林 《天津科技大学学报》 2025年第1期64-71,共8页
识别和预测特定药物与疾病之间的关联关系,是药物研发过程中必不可少的一部分。现有方法对药物和疾病的多种异源信息整合不足。本文提出了一种基于多核学习和图卷积网络的计算方法预测药物-疾病关联。首先,对于药物相似度,基于药物-疾... 识别和预测特定药物与疾病之间的关联关系,是药物研发过程中必不可少的一部分。现有方法对药物和疾病的多种异源信息整合不足。本文提出了一种基于多核学习和图卷积网络的计算方法预测药物-疾病关联。首先,对于药物相似度,基于药物-疾病关联矩阵和药物化学结构特征信息构建多个相似度核矩阵;同样,对于疾病相似度,基于关联矩阵构建多个相似度矩阵,并结合疾病语义相似度。其次,对这些相似度矩阵使用基于中心核对齐的多核学习算法进行整合。然后,构建基于图卷积网络的模型处理相似度网络和关联网络,从而提取药物和疾病特征。最后,使用内积解码器预测药物-疾病关联。与现有方法对比,本预测模型可以更准确地预测药物-疾病关联。 展开更多
关键词 药物 疾病 药物-疾病关联 多核学习 图卷积网络
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基于多模态图神经网络的miRNA-疾病关联预测模型
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作者 顾丽丽 蒋静梅 +5 位作者 王慧静 李矗矗 鲍振申 谢斌 孙思 刘文斌 《广州大学学报(自然科学版)》 2025年第6期78-88,共11页
研究表明,miRNAs与多种疾病的发生发展密切相关。因此,识别miRNA-疾病关联(MDAs)不仅有助于理解疾病发病机制,而且能为开发靶向miRNAs的有效疗法奠定基础。相较于传统生物实验方法,通过计算方法识别MDAs已被证实具有成本低、效率高的优... 研究表明,miRNAs与多种疾病的发生发展密切相关。因此,识别miRNA-疾病关联(MDAs)不仅有助于理解疾病发病机制,而且能为开发靶向miRNAs的有效疗法奠定基础。相较于传统生物实验方法,通过计算方法识别MDAs已被证实具有成本低、效率高的优势。该研究提出一种名为MDAES的新型预测方法,该方法通过整合miRNAs表达数据和相似性网络实现MDAs预测。在MDAES中,首先采用多核学习(MKL)技术从miRNAs和疾病的相似性核矩阵中构建最优核矩阵;其次,运用回归模型获取miRNAs与疾病的特征表示;最后,通过融合miRNAs与疾病的相似性网络特征及miRNAs表达数据特征作为深度神经网络(DNN)的输入,实现MDAs预测。实验结果显示,MDAES在3个基准数据集上均表现出色(AUC均值>0.95),其性能优于现有主流方法。针对乳腺癌和肺癌的案例研究证实,预测结果前30个miRNAs中分别有96%与100%与相应癌症存在关联。总体而言,MDAES作为一种可靠且实用的预测模型,在MDAs识别方面具有良好潜力。 展开更多
关键词 miRNA-疾病关联 多核学习 深度神经网络 相似性网络 链接预测
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多核学习方法 被引量:156
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作者 汪洪桥 孙富春 +2 位作者 蔡艳宁 陈宁 丁林阁 《自动化学报》 EI CSCD 北大核心 2010年第8期1037-1050,共14页
多核学习方法是当前核机器学习领域的一个新的热点.核方法是解决非线性模式分析问题的一种有效方法,但在一些复杂情形下,由单个核函数构成的核机器并不能满足诸如数据异构或不规则、样本规模巨大、样本不平坦分布等实际的应用需求,因此... 多核学习方法是当前核机器学习领域的一个新的热点.核方法是解决非线性模式分析问题的一种有效方法,但在一些复杂情形下,由单个核函数构成的核机器并不能满足诸如数据异构或不规则、样本规模巨大、样本不平坦分布等实际的应用需求,因此将多个核函数进行组合,以获得更好的结果是一种必然选择.本文根据多核的构成,从合成核、多尺度核、无限核三个角度,系统综述了多核方法的构造理论,分析了多核学习典型方法的特点及不足,总结了各自的应用领域,并凝炼了其进一步的研究方向. 展开更多
关键词 核方法 多核学习 合成核 多尺度核 支持向量机 模式识别 回归
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应用多分类多核学习支持向量机的变压器故障诊断方法 被引量:97
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作者 郭创新 朱承治 +2 位作者 张琳 彭明伟 刘毅 《中国电机工程学报》 EI CSCD 北大核心 2010年第13期128-134,共7页
提出一种基于多分类多核学习支持向量机的变压器故障诊断方法,相对于传统的2分类支持向量机,该方法有如下特点:算法针对单一的优化目标函数求解,只需设计1组参数,降低了支持向量机在解决多类问题中模型构造和参数选择的难度;核函数是多... 提出一种基于多分类多核学习支持向量机的变压器故障诊断方法,相对于传统的2分类支持向量机,该方法有如下特点:算法针对单一的优化目标函数求解,只需设计1组参数,降低了支持向量机在解决多类问题中模型构造和参数选择的难度;核函数是多个基核函数的组合,提高了分类的精度;将模型分解为2个凸优问题进行求解,问题的复杂度低,求解速度快。诊断实例表明,该方法能保证较高的诊断准确率,具有较好的实用性和推广性。 展开更多
关键词 变压器 故障诊断 支持向量机 多分类多核学习
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