针对现有 L on Works产品只提供 Neuron C指令语言编程环境的缺陷 ,设计开发研制成功一套提供可视化图形控制组态软件平台的 L on Works现场总线控制系统产品 CS2 0 0 0 .文中给出了该系统产品研制过程中采用的面向Agent生命周期法的技...针对现有 L on Works产品只提供 Neuron C指令语言编程环境的缺陷 ,设计开发研制成功一套提供可视化图形控制组态软件平台的 L on Works现场总线控制系统产品 CS2 0 0 0 .文中给出了该系统产品研制过程中采用的面向Agent生命周期法的技术路线 ,说明了系统分析与设计的实施步骤 ,并具体阐述了硬件节点和控制组态软件平台的关键实现技术 .该系统产品目前已成功应用于楼宇自动化和工业自动化的工程项目中 。展开更多
Dextran-poly（glycidyl methacrylate） （Dex-PGMA） nano-suitcases were synthesized efficiently via a graft copolymerization induced self-assembly （GISA） approach. On this basis, the Dex-PGMA nano-suitcases were modi...Dextran-poly（glycidyl methacrylate） （Dex-PGMA） nano-suitcases were synthesized efficiently via a graft copolymerization induced self-assembly （GISA） approach. On this basis, the Dex-PGMA nano-suitcases were modified with hydrazide, and the attachment of multiple chelated Gd（III） ions to the interior of the nano-suitcases affords nanoscale MRI contrast agents with high relaxivity values. The highly fenestrated dextran shell of the nano-suitcases assures water exchange which readily occurs between the surrounding environment and the Gd（III） ions encapsulated within the hybrid nano-suitcases. The complexation between the hydrophilic hydrazide interior of the nano-suitcases and Gd（III） ions results in an impressive Gd payload at 22.6 wt% in the hybrid nano-suitcases. The longitudinal relaxivity （rl） of the hybrid nano-suitcases is reported as 44.4 L/（mmol-s）, which is 9-14 folds of that of commercial Gd-DTPA agents. In vivo MRI studies demonstrate that the hybrid nano-suitcases accumulated in the lymph node of the rat due to their nanoscale dimensions and displayed strong signals in vivo. The results indicated that the hybrid nano-suitcases provide a promising platform for the diagnosis of lymph node related diseases.展开更多
文摘针对现有 L on Works产品只提供 Neuron C指令语言编程环境的缺陷 ,设计开发研制成功一套提供可视化图形控制组态软件平台的 L on Works现场总线控制系统产品 CS2 0 0 0 .文中给出了该系统产品研制过程中采用的面向Agent生命周期法的技术路线 ,说明了系统分析与设计的实施步骤 ,并具体阐述了硬件节点和控制组态软件平台的关键实现技术 .该系统产品目前已成功应用于楼宇自动化和工业自动化的工程项目中 。
基金financially supported by the National Natural Science Foundation of China(Nos.21374061,81371703 and 81501571)the Marie Curie International Incoming Fellowship of the EU+2 种基金the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning“Shu Guang”project supported by Shanghai Municipal Education CommissionShanghai Education Development Foundation
文摘Dextran-poly（glycidyl methacrylate） （Dex-PGMA） nano-suitcases were synthesized efficiently via a graft copolymerization induced self-assembly （GISA） approach. On this basis, the Dex-PGMA nano-suitcases were modified with hydrazide, and the attachment of multiple chelated Gd（III） ions to the interior of the nano-suitcases affords nanoscale MRI contrast agents with high relaxivity values. The highly fenestrated dextran shell of the nano-suitcases assures water exchange which readily occurs between the surrounding environment and the Gd（III） ions encapsulated within the hybrid nano-suitcases. The complexation between the hydrophilic hydrazide interior of the nano-suitcases and Gd（III） ions results in an impressive Gd payload at 22.6 wt% in the hybrid nano-suitcases. The longitudinal relaxivity （rl） of the hybrid nano-suitcases is reported as 44.4 L/（mmol-s）, which is 9-14 folds of that of commercial Gd-DTPA agents. In vivo MRI studies demonstrate that the hybrid nano-suitcases accumulated in the lymph node of the rat due to their nanoscale dimensions and displayed strong signals in vivo. The results indicated that the hybrid nano-suitcases provide a promising platform for the diagnosis of lymph node related diseases.
