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Multiple characteristic structure fragments scans coupled to high-resolution mass spectrometry strategy for discovering unknown structural analogs of mycotoxins in food
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作者 Dongwei Cui Xiuli Xu +7 位作者 Xiujuan Wang Feng Zhang Fengming Chen Tong Liu Han Wang Yuan Zhang Yaxuan Song Xuesong Feng 《Journal of Future Foods》 2022年第2期167-176,共10页
The cereals and their products,which have been easily infected by fungi and contaminated with mycotoxins,are serious threat to both human and animals alike.And yet,detection of these unknown fungal infection and mycot... The cereals and their products,which have been easily infected by fungi and contaminated with mycotoxins,are serious threat to both human and animals alike.And yet,detection of these unknown fungal infection and mycotoxins contaminates remains a great challenge.In this work,a holistic approach based on multiple characteristic structure fragments scans and high-resolution mass spectrometry(HRMS)was proposed for discovering unknown structural analogues of mycotoxins.The structural similarity of the same class of compounds provides a direction for the discovery and identification of unknown structural analogues of mycotoxins.The following steps were carried out:the fragmentation pathways of four types of mycotoxins were elucidated through comprehensive fragment analysis.By the combination of fragmentation pathways,the multiple characteristic structure fragments were screened out,with the common fragments were obtained by Veen diagram.Finally multiple characteristic structure fragments scans were carried out to find the unknown structural analogues of mycotoxins.The approach,first proposed by us,was proved to be effective in discovering and identifying 5 structural analogues of mycotoxins in real samples.It was proved to be a simple,fast and accurate method for early detection of fungal infection and mycotoxin contaminants,even for trace amounts of chemicals in complex matrix,and is of great significance to prevent hazardous substances infection from the food supply chains worldwide. 展开更多
关键词 Mycotoxins Fragmentation pathways multiple characteristic structure fragments scans HRMS
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On Test Data Compression Using Selective Don't-Care Identification 被引量:1
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作者 TerumineHayashi HarunaYoshioka TsuyoshiShinogi HidehikoKita HaruhikoTakase 《Journal of Computer Science & Technology》 SCIE EI CSCD 2005年第2期210-215,共6页
This paper proposes an effective method for reducing test data volume undermultiple scan chain designs. The proposed method is based on reduction of distinct scan vectorsusing selective don't-care identification. ... This paper proposes an effective method for reducing test data volume undermultiple scan chain designs. The proposed method is based on reduction of distinct scan vectorsusing selective don't-care identification. Selective don't-care identification is repeatedlyexecuted under condition that each bit of frequent scan vectors is fixed to binary values (0 or 1).Besides, a code extension technique is adopted for improving compression efficiency with keepingdecompressor circuits simple in the manner that the code length for infrequent scan vectors isdesigned as double of that for frequent ones. The effectiveness of the proposed method is shownthrough experiments for ISCAS'89 and ITC'99 benchmark circuits. 展开更多
关键词 test data compression multiple scan structure don''t-care identification test cost reduction
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