Flood disasters can have a serious impact on people's production and lives, and can cause hugelosses in lives and property security. Based on multi-source remote sensing data, this study establisheddecision tree c...Flood disasters can have a serious impact on people's production and lives, and can cause hugelosses in lives and property security. Based on multi-source remote sensing data, this study establisheddecision tree classification rules through multi-source and multi-temporal feature fusion, classified groundobjects before the disaster and extracted flood information in the disaster area based on optical imagesduring the disaster, so as to achieve rapid acquisition of the disaster situation of each disaster bearing object.In the case of Qianliang Lake, which suffered from flooding in 2020, the results show that decision treeclassification algorithms based on multi-temporal features can effectively integrate multi-temporal and multispectralinformation to overcome the shortcomings of single-temporal image classification and achieveground-truth object classification.展开更多
Landslide susceptibility map(LSM)is a crucial tool for managing landslide hazards and identifying potential landslide areas.However,current LSMs rely primarily on static landslide-related factors with little variation...Landslide susceptibility map(LSM)is a crucial tool for managing landslide hazards and identifying potential landslide areas.However,current LSMs rely primarily on static landslide-related factors with little variation over several decades,thereby overlooking the movement of slopes and failing to capture landslide dynamics.The long-term ground deformation map(GDM)derived from multi-temporal interferometric synthetic aperture radar(MT-InSAR)can effectively address the shortcomings.Fengjie County is an important area for geohazard management in the Three Gorges Reservoir Area(TGRA),China.Landslides in this area,however,cause significant socio-economic loss due to geological,tectonic,climatic,and anthropological factors.This research aims to integrate random forest(RF)with MT-InSAR to generate a landslide dynamic susceptibility map(LDSM)for Fengjie County,enhancing the reliability of landslide risk management.First,the RF model was employed to generate a static LSM,whereas MT-InSAR was utilized to obtain the GDM of the study area from January 2020 to June 2023.The static LSM and the GDM were subsequently integrated using a dynamic weight matrix to derive the LDSM.Our analysis covered a temporal framework spanning three years,focusing on spatiotemporal changes in landslide susceptibility levels and the influence of climate factors.Compared with the static LSM,the LDSM can promptly identify moving landslide areas,reduce high landslide susceptibility areas,and achieve greater accuracy.Moreover,the spatiotemporal changes in landslide susceptibility are regulated by the total annual rainfall,with wet years being more conducive to landslides than dry years.The proposed LDSM offers useful insights for the dynamic prevention and refined management of landslide hazards in the TGRA,significantly enhancing the resilience in this region.展开更多
[Background]High harmonic cavities are widely used in electron storage rings to lengthen thebunch,lower the bunch peak current,thereby reducing the IBS effect,enhancing the Touschek lifetime,as well asproviding Landau...[Background]High harmonic cavities are widely used in electron storage rings to lengthen thebunch,lower the bunch peak current,thereby reducing the IBS effect,enhancing the Touschek lifetime,as well asproviding Landau damping,which is particularly important for storage rings operating with ultra-low emittance or atlow beam energy.[Purpose]To further increase the bunch length without additional hardware costs,the phasemodulation in a dual-RF system is considered.[Methods]In this paper,turn-by-turn simulations incorporating randomsynchrotron radiation excitation are conducted,and a brief analysis is presented to explain the bunch lengtheningmechanism.[Results]Simulation results reveal that the peak current can be further reduced,thereby mitigating IBSeffects and enhancing the Touschek lifetime.Although the energy spread increases,which tends to reduce thebrightness of higher-harmonic radiation from the undulator,the brightness of the fundamental harmonic can,in fact,beimproved.展开更多
A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5w...A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively.展开更多
Optical phase-gradient metasurfaces have garnered significant attention for enabling flexible light manipulation,with applications across diverse domains.In this work,we will demonstrate that the metasurfaces with pha...Optical phase-gradient metasurfaces have garnered significant attention for enabling flexible light manipulation,with applications across diverse domains.In this work,we will demonstrate that the metasurfaces with phase gradient modulation can be used to achieve illusion optics,featuring the advantages of simple geometric structure and feasible implementation compared with the well-known transformation optics method.The underlying mechanism is the anomalous diffraction law caused by the phase gradient,which provides a theoretical basis for freely manipulating the propagation path of light.By considering a specific example,we will demonstrate that the phase gradient can transform spatial coordinates in real space into illusion space,thereby converting a plane in real space into a curved surface structure in illusion space to achieve the illusion effect.This approach provides a viable alternative to transformation optics for designing illusion devices.展开更多
The water-quenched(WQ)2195 Al−Li alloy was subjected to stretching at different temperatures,from room temperature(RT)to−196℃(CT),to investigate the effect of cryogenic deformation on the aging precipitation behavior...The water-quenched(WQ)2195 Al−Li alloy was subjected to stretching at different temperatures,from room temperature(RT)to−196℃(CT),to investigate the effect of cryogenic deformation on the aging precipitation behaviors and mechanical properties.The precipitation kinetics of the T1 phase and the microstructures in peak aging state were investigated through the differential scanning calorimetric(DSC)tests and electron microscopy observation.The results show that−196℃deformation produces a high dislocation density,which promotes the precipitation of the T1 phase and refines its sizes significantly.In addition,the grain boundary precipitates(GBPs)of−196℃-stretched samples are suppressed considerably due to the high dislocation density in the grain interiors,which increases the ductility.In comparison,the strength remains nearly constant.Thus,it is indicated that cryogenic forming has the potential to provide the shape and property control for the manufacture of critical components of aluminum alloys.展开更多
Beryllium-containing sludge(BCS)is a typical hazardous waste from Be smelting,which can cause serious harm to ecology and human health by releasing harmful Be if it is stored long-term in environment.Nonetheless,the o...Beryllium-containing sludge(BCS)is a typical hazardous waste from Be smelting,which can cause serious harm to ecology and human health by releasing harmful Be if it is stored long-term in environment.Nonetheless,the occurrence of Be in BCS is unclear,which seriously hinders the development of pollution control technologies.In order to enhance the understanding of BCS,the occurrence of Be and the microscale interactions with coexisting phases were investigated for the first time.It was found that CaSO_(4)·2H_(2)O and amorphous SiO_(2) are the primary phases of BCS.The simulated experiments of purified materials showed that Be interacted with CaSO_(4)·2H_(2)O and amorphous SiO_(2).Be can enter into the lattice of CaSO_(4)·2H_(2)O mainly as free Be2+.Amorphous SiO_(2) can adsorb Be2+particularly at a pH range of 3–5.The dissolution behavior experiment of BCS shows that about 52%of the Be is readily extracted under acidic conditions,which refers to the Be of independent occurrence.In contrast,the remaining 48%of Be can be extracted only after the CaSO_(4)·2H_(2)O has completely dissolved.Hence,CaSO_(4)·2H_(2)O is identified as the key occurrence phase which determines the highly efficient dissolution of Be.As a result,this study enhances the understanding of BCS and lays the foundation for the development of Be separation technologies.展开更多
Glacier area changes in the Qangtang Plateau are analyzed during 1970-2000 using air photos,relevant photogrammetric maps and satellite images based on the multi-temporal grid method.The results indicate that the melt...Glacier area changes in the Qangtang Plateau are analyzed during 1970-2000 using air photos,relevant photogrammetric maps and satellite images based on the multi-temporal grid method.The results indicate that the melting of glaciers accelerated,only a few of glaciers in an advancing state during 1970-2000 in the whole Qangtang Plateau.However,the glaciers seemed still more stable in the study area than in most areas of western China.We estimate that glacier retreat was likely due to air temperature warming during 1970-2000 in the Qangtang Plateau.Furthermore,the functional model of glacier system is applied to study climate sensitivity of glacier area changes,which indicates that glacier lifespan mainly depends on the heating rate,secondly the precipitation,and precipitation increasing can slow down glacier retreat and make glacier lifespan prolonged.展开更多
Pre-harvest yield prediction of ratoon rice is critical for guiding crop interventions in precision agriculture.However,the unique agronomic practice(i.e.,varied stubble height treatment)in rice ratooning could lead t...Pre-harvest yield prediction of ratoon rice is critical for guiding crop interventions in precision agriculture.However,the unique agronomic practice(i.e.,varied stubble height treatment)in rice ratooning could lead to inconsistent rice phenology,which had a significant impact on yield prediction of ratoon rice.Multi-temporal unmanned aerial vehicle(UAV)-based remote sensing can likely monitor ratoon rice productivity and reflect maximum yield potential across growing seasons for improving the yield prediction compared with previous methods.Thus,in this study,we explored the performance of combination of agronomic practice information(API)and single-phase,multi-spectral features[vegetation indices(VIs)and texture(Tex)features]in predicting ratoon rice yield,and developed a new UAV-based method to retrieve yield formation process by using multi-temporal features which were effective in improving yield forecasting accuracy of ratoon rice.The results showed that the integrated use of VIs,Tex and API(VIs&Tex+API)improved the accuracy of yield prediction than single-phase UAV imagery-based feature,with the panicle initiation stage being the best period for yield prediction(R^(2) as 0.732,RMSE as 0.406,RRMSE as 0.101).More importantly,compared with previous multi-temporal UAV-based methods,our proposed multi-temporal method(multi-temporal model VIs&Tex:R^(2) as 0.795,RMSE as 0.298,RRMSE as 0.072)can increase R^(2) by 0.020-0.111 and decrease RMSE by 0.020-0.080 in crop yield forecasting.This study provides an effective method for accurate pre-harvest yield prediction of ratoon rice in precision agriculture,which is of great significance to take timely means for ensuring ratoon rice production and food security.展开更多
Estimating wheat grain protein content by remote sensing is important for assessing wheat quality at maturity and making grains harvest and purchase policies. However, spatial variability of soil condition, temperatur...Estimating wheat grain protein content by remote sensing is important for assessing wheat quality at maturity and making grains harvest and purchase policies. However, spatial variability of soil condition, temperature, and precipitation will affect grain protein contents and these factors usually cannot be monitored accurately by remote sensing data from single image. In this research, the relationships between wheat protein content at maturity and wheat agronomic parameters at different growing stages were analyzed and multi-temporal images of Landsat TM were used to estimate grain protein content by partial least squares regression. Experiment data were acquired in the suburb of Beijing during a 2-yr experiment in the period from 2003 to 2004. Determination coefficient, average deviation of self-modeling, and deviation of cross- validation were employed to assess the estimation accuracy of wheat grain protein content. Their values were 0.88, 1.30%, 3.81% and 0.72, 5.22%, 12.36% for 2003 and 2004, respectively. The research laid an agronomic foundation for GPC （grain protein content） estimation by multi-temporal remote sensing. The results showed that it is feasible to estimate GPC of wheat from multi-temporal remote sensing data in large area.展开更多
Multi-temporal Interferometric Synthetic Aperture Radar(MT-InSAR) is one of the most powerful Earth observation techniques, especially useful for measuring highly detailed ground deformation over large ground areas. M...Multi-temporal Interferometric Synthetic Aperture Radar(MT-InSAR) is one of the most powerful Earth observation techniques, especially useful for measuring highly detailed ground deformation over large ground areas. Much research has been carried out to apply MT-InSAR to monitor ground and infrastructure deformation in urban areas related to land reclamation, underground construction and groundwater extraction.This paper reviews the progress in the research and identifies challenges in applying the technology, including the inconsistency in coherent point identification when different approaches are used, the reliability issue in parameter estimation, difficulty in accurate geolocation of measured points, the one-dimensional line-of-sight nature of InSAR measurements, the inability of making complete measurements over an area due to geometric distortions, especially the shadowing effects, the challenges in processing large SAR datasets, the decrease of the number of coherent points with the increase of the length of SAR time series, and the difficulty in quality control of MT-InSAR results.展开更多
Monitoring and early warning is an important means to effectively prevent risks in agricultural production,consumption and price.In particular,with the change of modes of national administration against the background...Monitoring and early warning is an important means to effectively prevent risks in agricultural production,consumption and price.In particular,with the change of modes of national administration against the background of big data,improving the capacity to monitor agricultural products is of great significance for macroeconomic decision-making.Agricultural product information early warning thresholds are the core of agricultural product monitoring and early warning.How to appropriately determine the early warning thresholds of multi-temporal agricultural product information is a key question to realize real-time and dynamic monitoring and early warning.Based on the theory of abnormal fluctuation of agricultural product information and the research of substantive impact on the society,this paper comprehensively discussed the methods to determine the thresholds of agricultural product information fluctuation in different time dimensions.Based on the data of the National Bureau of Statistics of China(NBSC)and survey data,this paper used a variety of statistical methods to determine the early warning thresholds of the production,consumption and prices of agricultural products.Combined with Delphi expert judgment correction method,it finally determined the early warning thresholds of agricultural product information in multiple time,and carried out early warning analysis on the fluctuation of agricultural product monitoring information in 2018.The results show that:(1)the daily,weekly and monthly monitoring and early warning thresholds of agricultural products play an important early warning role in monitoring abnormal fluctuations with agricultural products;(2)the multitemporal monitoring and early warning thresholds of agricultural product information identified by the research institute can provide effective early warning on current abnormal fluctuation of agricultural product information,provide a benchmarking standard for China's agricultural production,consumption and price monitoring and early warning at the national macro level,and further improve the application of China's agricultural product monitoring and early warning.展开更多
As a consumed and influential natural plant beverage,tea is widely planted in subtropical and tropical areas all over the world.Affected by(sub)tropical climate characteristics,the underlying surface of the tea distri...As a consumed and influential natural plant beverage,tea is widely planted in subtropical and tropical areas all over the world.Affected by(sub)tropical climate characteristics,the underlying surface of the tea distribution area is extremely complex,with a variety of vegetation types.In addition,tea distribution is scattered and fragmentized in most of China.Therefore,it is difficult to obtain accurate tea information based on coarse resolution remote sensing data and existing feature extraction methods.This study proposed a boundary-enhanced,object-oriented random forest method on the basis of high-resolution GF-2 and multi-temporal Sentinel-2 data.This method uses multispectral indexes,textures,vegetable indices,and variation characteristics of time-series NDVI from the multi-temporal Sentinel-2 imageries to obtain abundant features related to the growth of tea plantations.To reduce feature redundancy and computation time,the feature elimination algorithm based on Mean Decrease Accuracy(MDA)was used to generate the optimal feature set.Considering the serious boundary inconsistency problem caused by the complex and fragmented land cover types,high resolution GF-2 image was segmented based on the MultiResolution Segmentation(MRS)algorithm to assist the segmentation of Sentinel-2,which contributes to delineating meaningful objects and enhancing the reliability of the boundary for tea plantations.Finally,the object-oriented random forest method was utilized to extract the tea information based on the optimal feature combination in the Jingmai Mountain,Yunnan Province.The resulting tea plantation map had high accuracy,with a 95.38%overall accuracy and 0.91 kappa coefficient.We conclude that the proposed method is effective for mapping tea plantations in high heterogeneity mountainous areas and has the potential for mapping tea plantations in large areas.展开更多
Conventional change detection approaches are mainly based on per-pixel processing,which ignore the sub-pixel spectral variation resulted from spectral mixture.Especially for medium-resolution remote sensing images use...Conventional change detection approaches are mainly based on per-pixel processing,which ignore the sub-pixel spectral variation resulted from spectral mixture.Especially for medium-resolution remote sensing images used in urban landcover change monitoring,land use/cover components within a single pixel are usually complicated and heterogeneous due to the limitation of the spatial resolution.Thus,traditional hard detection methods based on pure pixel assumption may lead to a high level of omission and commission errors inevitably,degrading the overall accuracy of change detection.In order to address this issue and find a possible way to exploit the spectral variation in a sub-pixel level,a novel change detection scheme is designed based on the spectral mixture analysis and decision-level fusion.Nonlinear spectral mixture model is selected for spectral unmixing,and change detection is implemented in a sub-pixel level by investigating the inner-pixel subtle changes and combining multiple composition evidences.The proposed method is tested on multi-temporal Landsat Thematic Mapper and China–Brazil Earth Resources Satellite remote sensing images for the land-cover change detection over urban areas.The effectiveness of the proposed approach is confirmed in terms of several accuracy indices in contrast with two pixel-based change detection methods(i.e.change vector analysis and principal component analysis-based method).In particular,the proposed sub-pixel change detection approach not only provides the binary change information,but also obtains the characterization about change direction and intensity,which greatly extends the semantic meaning of the detected change targets.展开更多
Land subsidence is a major factor that affects metro line （ML） stability. In this study, an improved multi- temporal interferometric synthetic aperture radar （InSAR） （MTI） method to detect land subsidence near M...Land subsidence is a major factor that affects metro line （ML） stability. In this study, an improved multi- temporal interferometric synthetic aperture radar （InSAR） （MTI） method to detect land subsidence near MLs is presented. In particular, our multi-temporal InSAR method provides surface subsidence measurements with high observation density. The MTI method tracks both point-like targets and distributed targets with temporal radar back- scattering steadiness. First, subsidence rates at the point targets with low-amplitude dispersion index （ADI） values are extracted by applying a least-squared estimator on an optimized freely connected network. Second, to reduce error propagation, the pixels with high-ADI values are classified into several groups according to ADI intervals and processed using a Pearson correlation coefficient and hierarchical analysis strategy to obtain the distributed targets. Then, nonlinear subsidence components at all point-like and distributed targets are estimated using phase unwrapping and spatiotemporal filtering on the phase residuals. The proposed MTI method was applied to detect land subsidence near MLs of No. 1 and 3 in the Baoshan district of Shanghai using 18 TerraSAR-X images acquired between April 21, 2008 and October 30, 2010. The results show that the mean subsidence rates of the stations distributed along the two MLs are -12.9 and -14.0 ram/year. Furthermore, three subsidence funnels near the MLs are discovered through the hierarchical analysis. The testing results demonstrate the satisfactory capacity of the proposed MTI method in providing detailed subsidence information near MLs.展开更多
This study conducted computer-aided image analysis of land use and land cover in Xilin River Basin, Inner Mongolia, using 4 sets of Landsat TM/ETM+ images acquired on July 31, 1987, August 11, 1991, Sep...This study conducted computer-aided image analysis of land use and land cover in Xilin River Basin, Inner Mongolia, using 4 sets of Landsat TM/ETM+ images acquired on July 31, 1987, August 11, 1991, September 27, 1997 and May 23, 2000, respectively. Primarily, 17 sub-class land cover types were recognized, including nine grassland types at community level: F.sibiricum steppe, S.baicalensis steppe, A.chinensis+ forbs steppe, A.chinensis+ bunchgrass steppe, A.chinensis+ Ar.frigida steppe, S.grandis+ A.chinensis steppe, S.grandis+ bunchgrass steppe, S.krylavii steppe, Ar.frigida steppe and eight non-grassland types: active cropland, harvested cropland, urban area, wetland, desertified land, saline and alkaline land, cloud, water body + cloud shadow. To eliminate the classification error existing among different sub-types of the same gross type, the 17 sub-class land cover types were grouped into five gross types: meadow grassland, temperate grassland, desert grassland, cropland and non-grassland. The overall classification accuracy of the five land cover types was 81.0% for 1987, 81.7% for 1991, 80.1% for 1997 and 78.2% for 2000.展开更多
Satellite images are considered reliable data that preserve land cover information. In the field of remote sensing, these images allow relevant analyses of changes in space over time through the use of computer tools....Satellite images are considered reliable data that preserve land cover information. In the field of remote sensing, these images allow relevant analyses of changes in space over time through the use of computer tools. In this study, we have applied the “discriminant” change detection algorithm. In this, we have verified its effectiveness in multi-temporal studies. Also, we have determined the change in forest dynamics in the Ikongo district of Madagascar between 2000 and 2015. During the treatments, we have used the Landsat TM satellite images for the years 2000, 2005 and 2010 as well as ETM+ for 2015. Thus, analyses carried out have allowed us to note that between 2000-2005, 1.4% of natural forest disappeared. And, between 2005-2010, forests degradation<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">was 1.8%. Also, between 2010-2015, about 0.5% of the natural forest conserved in 2010 disappeared. Furthermore, we have found that the discriminant algorithm is considerably efficient in terms of monitoring the dynamics of forest cover change.</span></span></span>展开更多
As landmass of the world is covered by vegetation, taking into account phenology when performing land cover classification may yield more accurate maps. The availability of no-cost Moderate Resolution Imaging Spectrom...As landmass of the world is covered by vegetation, taking into account phenology when performing land cover classification may yield more accurate maps. The availability of no-cost Moderate Resolution Imaging Spectrometer (MODIS) NDVI dataset that provides high-quality continuous time series data is representing a potentially significant source of land cover information especially for detection natural forest distribution. This study intends to assess the advantage of MODIS 250 m Normalized Difference Vegetation Index (NDVI) multi-temporal imagery for detection of densely vegetation cover distribution in Java and then for identification of remaining natural forest in Java from densely vegetation cover distribution. Result of this study successfully demonstrated the contribution of MODIS NDVI 250 m for detection the natural forest distribution in Java Island. Therefore, the approach described herein provided classification accuracy comparable to those of maps derived from higher resolution data and will be a viable alternative for regional or national classifications.展开更多
Spinal cord injury is an intractable traumatic injury. The most common hurdles faced during spinal cord injury are failure of axonal regrowth and reconnection to target sites. These also tend to be the most challengin...Spinal cord injury is an intractable traumatic injury. The most common hurdles faced during spinal cord injury are failure of axonal regrowth and reconnection to target sites. These also tend to be the most challenging issues in spinal cord injury. As spinal cord injury progresses to the chronic phase, lost motor and sensory functions are not recovered. Several reasons may be attributed to the failure of recovery from chronic spinal cord injury. These include factors that inhibit axonal growth such as activated astrocytes, chondroitin sulfate proteoglycan, myelin-associated proteins, inflammatory microglia, and fibroblasts that accumulate at lesion sites. Skeletal muscle atrophy due to denervation is another chronic and detrimental spinal cord injury–specific condition. Although several intervention strategies based on multiple outlooks have been attempted for treating spinal cord injury, few approaches have been successful. To treat chronic spinal cord injury, neural cells or tissue substitutes may need to be supplied in the cavity area to enable possible axonal growth. Additionally, stimulating axonal growth activity by extrinsic factors is extremely important and essential for maintaining the remaining host neurons and transplanted neurons. This review focuses on pharmacotherapeutic approaches using small compounds and proteins to enable axonal growth in chronic spinal cord injury. This review presents some of these candidates that have shown promising outcomes in basic research(in vivo animal studies) and clinical trials: AA-NgR(310)ecto-Fc(AXER-204), fasudil, phosphatase and tensin homolog protein antagonist peptide 4, chondroitinase ABC, intracellular sigma peptide,(-)-epigallocatechin gallate, matrine, acteoside, pyrvate kinase M2, diosgenin, granulocyte-colony stimulating factor, and fampridine-sustained release. Although the current situation suggests that drug-based therapies to recover function in chronic spinal cord injury are limited, potential candidates have been identified through basic research, and these candidates may be subjects of clinical studies in the future. Moreover, cocktail therapy comprising drugs with varied underlying mechanisms may be effective in treating the refractory status of chronic spinal cord injury.展开更多
文摘Flood disasters can have a serious impact on people's production and lives, and can cause hugelosses in lives and property security. Based on multi-source remote sensing data, this study establisheddecision tree classification rules through multi-source and multi-temporal feature fusion, classified groundobjects before the disaster and extracted flood information in the disaster area based on optical imagesduring the disaster, so as to achieve rapid acquisition of the disaster situation of each disaster bearing object.In the case of Qianliang Lake, which suffered from flooding in 2020, the results show that decision treeclassification algorithms based on multi-temporal features can effectively integrate multi-temporal and multispectralinformation to overcome the shortcomings of single-temporal image classification and achieveground-truth object classification.
基金supported by the National Science Fund for Distinguished Young Scholars(Grant No.42225702)the Maria Skłodowska-Curie Action(MSCA)-UPGRADE(mUltiscale IoT equipPed lonG linear infRastructure resilience built and sustAinable DevelopmEnt)project-HORIZON-MSCA-2022-SE-01(Grant No.101131146)。
文摘Landslide susceptibility map(LSM)is a crucial tool for managing landslide hazards and identifying potential landslide areas.However,current LSMs rely primarily on static landslide-related factors with little variation over several decades,thereby overlooking the movement of slopes and failing to capture landslide dynamics.The long-term ground deformation map(GDM)derived from multi-temporal interferometric synthetic aperture radar(MT-InSAR)can effectively address the shortcomings.Fengjie County is an important area for geohazard management in the Three Gorges Reservoir Area(TGRA),China.Landslides in this area,however,cause significant socio-economic loss due to geological,tectonic,climatic,and anthropological factors.This research aims to integrate random forest(RF)with MT-InSAR to generate a landslide dynamic susceptibility map(LDSM)for Fengjie County,enhancing the reliability of landslide risk management.First,the RF model was employed to generate a static LSM,whereas MT-InSAR was utilized to obtain the GDM of the study area from January 2020 to June 2023.The static LSM and the GDM were subsequently integrated using a dynamic weight matrix to derive the LDSM.Our analysis covered a temporal framework spanning three years,focusing on spatiotemporal changes in landslide susceptibility levels and the influence of climate factors.Compared with the static LSM,the LDSM can promptly identify moving landslide areas,reduce high landslide susceptibility areas,and achieve greater accuracy.Moreover,the spatiotemporal changes in landslide susceptibility are regulated by the total annual rainfall,with wet years being more conducive to landslides than dry years.The proposed LDSM offers useful insights for the dynamic prevention and refined management of landslide hazards in the TGRA,significantly enhancing the resilience in this region.
基金National Natural Science Foundation of China(12405168)The Fundamental Research Funds for the Central Universities,China(2024CDJXY004)。
文摘[Background]High harmonic cavities are widely used in electron storage rings to lengthen thebunch,lower the bunch peak current,thereby reducing the IBS effect,enhancing the Touschek lifetime,as well asproviding Landau damping,which is particularly important for storage rings operating with ultra-low emittance or atlow beam energy.[Purpose]To further increase the bunch length without additional hardware costs,the phasemodulation in a dual-RF system is considered.[Methods]In this paper,turn-by-turn simulations incorporating randomsynchrotron radiation excitation are conducted,and a brief analysis is presented to explain the bunch lengtheningmechanism.[Results]Simulation results reveal that the peak current can be further reduced,thereby mitigating IBSeffects and enhancing the Touschek lifetime.Although the energy spread increases,which tends to reduce thebrightness of higher-harmonic radiation from the undulator,the brightness of the fundamental harmonic can,in fact,beimproved.
基金Shaanxi Province Qin Chuangyuan“Scientist+Engineer”Team Construction Project(2022KXJ-071)2022 Qin Chuangyuan Achievement Transformation Incubation Capacity Improvement Project(2022JH-ZHFHTS-0012)+8 种基金Shaanxi Province Key Research and Development Plan-“Two Chains”Integration Key Project-Qin Chuangyuan General Window Industrial Cluster Project(2023QCY-LL-02)Xixian New Area Science and Technology Plan(2022-YXYJ-003,2022-XXCY-010)2024 Scientific Research Project of Shaanxi National Defense Industry Vocational and Technical College(Gfy24-07)Shaanxi Vocational and Technical Education Association 2024 Vocational Education Teaching Reform Research Topic(2024SZX354)National Natural Science Foundation of China(U24A20115)2024 Shaanxi Provincial Education Department Service Local Special Scientific Research Program Project-Industrialization Cultivation Project(24JC005,24JC063)Shaanxi Province“14th Five-Year Plan”Education Science Plan,2024 Project(SGH24Y3181)National Key Research and Development Program of China(2023YFB4606400)Longmen Laboratory Frontier Exploration Topics Project(LMQYTSKT003)。
文摘A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively.
基金supported by the National Natural Science Foundation of China (Grant Nos.12274313 and 62375234)the Gusu Leading Talent Plan for Scientific and Technological Innovation and Entrepreneurship (Grant No.ZXL2024400)。
文摘Optical phase-gradient metasurfaces have garnered significant attention for enabling flexible light manipulation,with applications across diverse domains.In this work,we will demonstrate that the metasurfaces with phase gradient modulation can be used to achieve illusion optics,featuring the advantages of simple geometric structure and feasible implementation compared with the well-known transformation optics method.The underlying mechanism is the anomalous diffraction law caused by the phase gradient,which provides a theoretical basis for freely manipulating the propagation path of light.By considering a specific example,we will demonstrate that the phase gradient can transform spatial coordinates in real space into illusion space,thereby converting a plane in real space into a curved surface structure in illusion space to achieve the illusion effect.This approach provides a viable alternative to transformation optics for designing illusion devices.
基金financially supported by the National Key Research and Development Program of China (No. 2019YFA0708801)the National Natural Science Foundation of China (No. 51875125)。
文摘The water-quenched(WQ)2195 Al−Li alloy was subjected to stretching at different temperatures,from room temperature(RT)to−196℃(CT),to investigate the effect of cryogenic deformation on the aging precipitation behaviors and mechanical properties.The precipitation kinetics of the T1 phase and the microstructures in peak aging state were investigated through the differential scanning calorimetric(DSC)tests and electron microscopy observation.The results show that−196℃deformation produces a high dislocation density,which promotes the precipitation of the T1 phase and refines its sizes significantly.In addition,the grain boundary precipitates(GBPs)of−196℃-stretched samples are suppressed considerably due to the high dislocation density in the grain interiors,which increases the ductility.In comparison,the strength remains nearly constant.Thus,it is indicated that cryogenic forming has the potential to provide the shape and property control for the manufacture of critical components of aluminum alloys.
基金supported by the National Natural Science Foundation of China(No.22276219)the foundation for Innovative Research Groups of the National Natural Science Foundation of China(No.52121004)+1 种基金the major program Natural Science Foundation of Hunan Province of China(No.2021JC0001)the Fundamental Research Funds for the Central Universities of Central South University(No.2024ZZTS0063).
文摘Beryllium-containing sludge(BCS)is a typical hazardous waste from Be smelting,which can cause serious harm to ecology and human health by releasing harmful Be if it is stored long-term in environment.Nonetheless,the occurrence of Be in BCS is unclear,which seriously hinders the development of pollution control technologies.In order to enhance the understanding of BCS,the occurrence of Be and the microscale interactions with coexisting phases were investigated for the first time.It was found that CaSO_(4)·2H_(2)O and amorphous SiO_(2) are the primary phases of BCS.The simulated experiments of purified materials showed that Be interacted with CaSO_(4)·2H_(2)O and amorphous SiO_(2).Be can enter into the lattice of CaSO_(4)·2H_(2)O mainly as free Be2+.Amorphous SiO_(2) can adsorb Be2+particularly at a pH range of 3–5.The dissolution behavior experiment of BCS shows that about 52%of the Be is readily extracted under acidic conditions,which refers to the Be of independent occurrence.In contrast,the remaining 48%of Be can be extracted only after the CaSO_(4)·2H_(2)O has completely dissolved.Hence,CaSO_(4)·2H_(2)O is identified as the key occurrence phase which determines the highly efficient dissolution of Be.As a result,this study enhances the understanding of BCS and lays the foundation for the development of Be separation technologies.
基金supported by the National Natural Science Foundation of China (Nos.40871043,40801025)the Project of National Scientific Basic Special Fund on the Ministry of Science and Technology of China (No.2006FY110200)the Key Construction Disciplines of Hunan Province (No.40652001)
文摘Glacier area changes in the Qangtang Plateau are analyzed during 1970-2000 using air photos,relevant photogrammetric maps and satellite images based on the multi-temporal grid method.The results indicate that the melting of glaciers accelerated,only a few of glaciers in an advancing state during 1970-2000 in the whole Qangtang Plateau.However,the glaciers seemed still more stable in the study area than in most areas of western China.We estimate that glacier retreat was likely due to air temperature warming during 1970-2000 in the Qangtang Plateau.Furthermore,the functional model of glacier system is applied to study climate sensitivity of glacier area changes,which indicates that glacier lifespan mainly depends on the heating rate,secondly the precipitation,and precipitation increasing can slow down glacier retreat and make glacier lifespan prolonged.
基金supported by the Key Research and Development Program of Heilongjiang,China(Grant No.2022ZX01A25)Cooperative Funding between Huazhong Agricultural University and Shenzhen Institute of Agricultural Genomics(Grant No.SZYJY2022014)+2 种基金Fundamental Research Funds for the Central Universities,Beijing,China(Grant Nos.2662022JC006 and 2662022ZHYJ002)National Natural Science Foundation of China(Grant No.32101819)Huazhong Agriculture University Research Startup Fund,China(Grant Nos.11041810340 and 11041810341).
文摘Pre-harvest yield prediction of ratoon rice is critical for guiding crop interventions in precision agriculture.However,the unique agronomic practice(i.e.,varied stubble height treatment)in rice ratooning could lead to inconsistent rice phenology,which had a significant impact on yield prediction of ratoon rice.Multi-temporal unmanned aerial vehicle(UAV)-based remote sensing can likely monitor ratoon rice productivity and reflect maximum yield potential across growing seasons for improving the yield prediction compared with previous methods.Thus,in this study,we explored the performance of combination of agronomic practice information(API)and single-phase,multi-spectral features[vegetation indices(VIs)and texture(Tex)features]in predicting ratoon rice yield,and developed a new UAV-based method to retrieve yield formation process by using multi-temporal features which were effective in improving yield forecasting accuracy of ratoon rice.The results showed that the integrated use of VIs,Tex and API(VIs&Tex+API)improved the accuracy of yield prediction than single-phase UAV imagery-based feature,with the panicle initiation stage being the best period for yield prediction(R^(2) as 0.732,RMSE as 0.406,RRMSE as 0.101).More importantly,compared with previous multi-temporal UAV-based methods,our proposed multi-temporal method(multi-temporal model VIs&Tex:R^(2) as 0.795,RMSE as 0.298,RRMSE as 0.072)can increase R^(2) by 0.020-0.111 and decrease RMSE by 0.020-0.080 in crop yield forecasting.This study provides an effective method for accurate pre-harvest yield prediction of ratoon rice in precision agriculture,which is of great significance to take timely means for ensuring ratoon rice production and food security.
基金the National Natural Science Foundation of China (41171281, 40701120)the Beijing Nova Program, China (2008B33)
文摘Estimating wheat grain protein content by remote sensing is important for assessing wheat quality at maturity and making grains harvest and purchase policies. However, spatial variability of soil condition, temperature, and precipitation will affect grain protein contents and these factors usually cannot be monitored accurately by remote sensing data from single image. In this research, the relationships between wheat protein content at maturity and wheat agronomic parameters at different growing stages were analyzed and multi-temporal images of Landsat TM were used to estimate grain protein content by partial least squares regression. Experiment data were acquired in the suburb of Beijing during a 2-yr experiment in the period from 2003 to 2004. Determination coefficient, average deviation of self-modeling, and deviation of cross- validation were employed to assess the estimation accuracy of wheat grain protein content. Their values were 0.88, 1.30%, 3.81% and 0.72, 5.22%, 12.36% for 2003 and 2004, respectively. The research laid an agronomic foundation for GPC （grain protein content） estimation by multi-temporal remote sensing. The results showed that it is feasible to estimate GPC of wheat from multi-temporal remote sensing data in large area.
基金The National Natural Science Foundation of China(41774023)The Research Grants Council(RGC)of Hong Kong(PolyU152232/17E,PolyU152164/18E),The Faculty of Construction and Environment(ZZGD)+1 种基金The Research Institute for Sustainable Urban Development(RISUD)(1-BBWB)The TerraSAR-X Science plan(GEO3603)。
文摘Multi-temporal Interferometric Synthetic Aperture Radar(MT-InSAR) is one of the most powerful Earth observation techniques, especially useful for measuring highly detailed ground deformation over large ground areas. Much research has been carried out to apply MT-InSAR to monitor ground and infrastructure deformation in urban areas related to land reclamation, underground construction and groundwater extraction.This paper reviews the progress in the research and identifies challenges in applying the technology, including the inconsistency in coherent point identification when different approaches are used, the reliability issue in parameter estimation, difficulty in accurate geolocation of measured points, the one-dimensional line-of-sight nature of InSAR measurements, the inability of making complete measurements over an area due to geometric distortions, especially the shadowing effects, the challenges in processing large SAR datasets, the decrease of the number of coherent points with the increase of the length of SAR time series, and the difficulty in quality control of MT-InSAR results.
基金The Science and Technoloav Innovation Program of the Chinese Academy of Agricultural Sciences(CAAS-ASTIP-2020-A11-02)is appreciated for supporting this study.
文摘Monitoring and early warning is an important means to effectively prevent risks in agricultural production,consumption and price.In particular,with the change of modes of national administration against the background of big data,improving the capacity to monitor agricultural products is of great significance for macroeconomic decision-making.Agricultural product information early warning thresholds are the core of agricultural product monitoring and early warning.How to appropriately determine the early warning thresholds of multi-temporal agricultural product information is a key question to realize real-time and dynamic monitoring and early warning.Based on the theory of abnormal fluctuation of agricultural product information and the research of substantive impact on the society,this paper comprehensively discussed the methods to determine the thresholds of agricultural product information fluctuation in different time dimensions.Based on the data of the National Bureau of Statistics of China(NBSC)and survey data,this paper used a variety of statistical methods to determine the early warning thresholds of the production,consumption and prices of agricultural products.Combined with Delphi expert judgment correction method,it finally determined the early warning thresholds of agricultural product information in multiple time,and carried out early warning analysis on the fluctuation of agricultural product monitoring information in 2018.The results show that:(1)the daily,weekly and monthly monitoring and early warning thresholds of agricultural products play an important early warning role in monitoring abnormal fluctuations with agricultural products;(2)the multitemporal monitoring and early warning thresholds of agricultural product information identified by the research institute can provide effective early warning on current abnormal fluctuation of agricultural product information,provide a benchmarking standard for China's agricultural production,consumption and price monitoring and early warning at the national macro level,and further improve the application of China's agricultural product monitoring and early warning.
基金National Natural Science Foundation of China(No.41830110)National Key Research Development Program of China(No.2018YFC1503603)+2 种基金Key Laboratory of Land Satellite Remote Sensing Application,Ministry of Natural Resources of the People’s Republic of China(No.KLSMNR-202106)Water Conservancy Science and Technology Project of Jiangsu Province,China(No.2020061)Natural Science Foundation of Jiangsu Province,China(No.20180779)。
文摘As a consumed and influential natural plant beverage,tea is widely planted in subtropical and tropical areas all over the world.Affected by(sub)tropical climate characteristics,the underlying surface of the tea distribution area is extremely complex,with a variety of vegetation types.In addition,tea distribution is scattered and fragmentized in most of China.Therefore,it is difficult to obtain accurate tea information based on coarse resolution remote sensing data and existing feature extraction methods.This study proposed a boundary-enhanced,object-oriented random forest method on the basis of high-resolution GF-2 and multi-temporal Sentinel-2 data.This method uses multispectral indexes,textures,vegetable indices,and variation characteristics of time-series NDVI from the multi-temporal Sentinel-2 imageries to obtain abundant features related to the growth of tea plantations.To reduce feature redundancy and computation time,the feature elimination algorithm based on Mean Decrease Accuracy(MDA)was used to generate the optimal feature set.Considering the serious boundary inconsistency problem caused by the complex and fragmented land cover types,high resolution GF-2 image was segmented based on the MultiResolution Segmentation(MRS)algorithm to assist the segmentation of Sentinel-2,which contributes to delineating meaningful objects and enhancing the reliability of the boundary for tea plantations.Finally,the object-oriented random forest method was utilized to extract the tea information based on the optimal feature combination in the Jingmai Mountain,Yunnan Province.The resulting tea plantation map had high accuracy,with a 95.38%overall accuracy and 0.91 kappa coefficient.We conclude that the proposed method is effective for mapping tea plantations in high heterogeneity mountainous areas and has the potential for mapping tea plantations in large areas.
基金partially supported by the National Natural Science Foundation of China(No.41171323)Jiangsu Provincial Natural Science Foundation(No.BK2012018)+2 种基金the Key Laboratory of Geo-Informatics of National Administration of Surveying,Mapping and Geoinformation of China(No.201109)partially supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)the Fundamental Research Funds for the Central Universities.
文摘Conventional change detection approaches are mainly based on per-pixel processing,which ignore the sub-pixel spectral variation resulted from spectral mixture.Especially for medium-resolution remote sensing images used in urban landcover change monitoring,land use/cover components within a single pixel are usually complicated and heterogeneous due to the limitation of the spatial resolution.Thus,traditional hard detection methods based on pure pixel assumption may lead to a high level of omission and commission errors inevitably,degrading the overall accuracy of change detection.In order to address this issue and find a possible way to exploit the spectral variation in a sub-pixel level,a novel change detection scheme is designed based on the spectral mixture analysis and decision-level fusion.Nonlinear spectral mixture model is selected for spectral unmixing,and change detection is implemented in a sub-pixel level by investigating the inner-pixel subtle changes and combining multiple composition evidences.The proposed method is tested on multi-temporal Landsat Thematic Mapper and China–Brazil Earth Resources Satellite remote sensing images for the land-cover change detection over urban areas.The effectiveness of the proposed approach is confirmed in terms of several accuracy indices in contrast with two pixel-based change detection methods(i.e.change vector analysis and principal component analysis-based method).In particular,the proposed sub-pixel change detection approach not only provides the binary change information,but also obtains the characterization about change direction and intensity,which greatly extends the semantic meaning of the detected change targets.
文摘Land subsidence is a major factor that affects metro line （ML） stability. In this study, an improved multi- temporal interferometric synthetic aperture radar （InSAR） （MTI） method to detect land subsidence near MLs is presented. In particular, our multi-temporal InSAR method provides surface subsidence measurements with high observation density. The MTI method tracks both point-like targets and distributed targets with temporal radar back- scattering steadiness. First, subsidence rates at the point targets with low-amplitude dispersion index （ADI） values are extracted by applying a least-squared estimator on an optimized freely connected network. Second, to reduce error propagation, the pixels with high-ADI values are classified into several groups according to ADI intervals and processed using a Pearson correlation coefficient and hierarchical analysis strategy to obtain the distributed targets. Then, nonlinear subsidence components at all point-like and distributed targets are estimated using phase unwrapping and spatiotemporal filtering on the phase residuals. The proposed MTI method was applied to detect land subsidence near MLs of No. 1 and 3 in the Baoshan district of Shanghai using 18 TerraSAR-X images acquired between April 21, 2008 and October 30, 2010. The results show that the mean subsidence rates of the stations distributed along the two MLs are -12.9 and -14.0 ram/year. Furthermore, three subsidence funnels near the MLs are discovered through the hierarchical analysis. The testing results demonstrate the satisfactory capacity of the proposed MTI method in providing detailed subsidence information near MLs.
基金Knowledge Innovation Project of CAS No.KZCX02-308+1 种基金 The NASA Land Use and Land Cover Change Program No.NAG5-11160
文摘This study conducted computer-aided image analysis of land use and land cover in Xilin River Basin, Inner Mongolia, using 4 sets of Landsat TM/ETM+ images acquired on July 31, 1987, August 11, 1991, September 27, 1997 and May 23, 2000, respectively. Primarily, 17 sub-class land cover types were recognized, including nine grassland types at community level: F.sibiricum steppe, S.baicalensis steppe, A.chinensis+ forbs steppe, A.chinensis+ bunchgrass steppe, A.chinensis+ Ar.frigida steppe, S.grandis+ A.chinensis steppe, S.grandis+ bunchgrass steppe, S.krylavii steppe, Ar.frigida steppe and eight non-grassland types: active cropland, harvested cropland, urban area, wetland, desertified land, saline and alkaline land, cloud, water body + cloud shadow. To eliminate the classification error existing among different sub-types of the same gross type, the 17 sub-class land cover types were grouped into five gross types: meadow grassland, temperate grassland, desert grassland, cropland and non-grassland. The overall classification accuracy of the five land cover types was 81.0% for 1987, 81.7% for 1991, 80.1% for 1997 and 78.2% for 2000.
文摘Satellite images are considered reliable data that preserve land cover information. In the field of remote sensing, these images allow relevant analyses of changes in space over time through the use of computer tools. In this study, we have applied the “discriminant” change detection algorithm. In this, we have verified its effectiveness in multi-temporal studies. Also, we have determined the change in forest dynamics in the Ikongo district of Madagascar between 2000 and 2015. During the treatments, we have used the Landsat TM satellite images for the years 2000, 2005 and 2010 as well as ETM+ for 2015. Thus, analyses carried out have allowed us to note that between 2000-2005, 1.4% of natural forest disappeared. And, between 2005-2010, forests degradation<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">was 1.8%. Also, between 2010-2015, about 0.5% of the natural forest conserved in 2010 disappeared. Furthermore, we have found that the discriminant algorithm is considerably efficient in terms of monitoring the dynamics of forest cover change.</span></span></span>
文摘As landmass of the world is covered by vegetation, taking into account phenology when performing land cover classification may yield more accurate maps. The availability of no-cost Moderate Resolution Imaging Spectrometer (MODIS) NDVI dataset that provides high-quality continuous time series data is representing a potentially significant source of land cover information especially for detection natural forest distribution. This study intends to assess the advantage of MODIS 250 m Normalized Difference Vegetation Index (NDVI) multi-temporal imagery for detection of densely vegetation cover distribution in Java and then for identification of remaining natural forest in Java from densely vegetation cover distribution. Result of this study successfully demonstrated the contribution of MODIS NDVI 250 m for detection the natural forest distribution in Java Island. Therefore, the approach described herein provided classification accuracy comparable to those of maps derived from higher resolution data and will be a viable alternative for regional or national classifications.
文摘Spinal cord injury is an intractable traumatic injury. The most common hurdles faced during spinal cord injury are failure of axonal regrowth and reconnection to target sites. These also tend to be the most challenging issues in spinal cord injury. As spinal cord injury progresses to the chronic phase, lost motor and sensory functions are not recovered. Several reasons may be attributed to the failure of recovery from chronic spinal cord injury. These include factors that inhibit axonal growth such as activated astrocytes, chondroitin sulfate proteoglycan, myelin-associated proteins, inflammatory microglia, and fibroblasts that accumulate at lesion sites. Skeletal muscle atrophy due to denervation is another chronic and detrimental spinal cord injury–specific condition. Although several intervention strategies based on multiple outlooks have been attempted for treating spinal cord injury, few approaches have been successful. To treat chronic spinal cord injury, neural cells or tissue substitutes may need to be supplied in the cavity area to enable possible axonal growth. Additionally, stimulating axonal growth activity by extrinsic factors is extremely important and essential for maintaining the remaining host neurons and transplanted neurons. This review focuses on pharmacotherapeutic approaches using small compounds and proteins to enable axonal growth in chronic spinal cord injury. This review presents some of these candidates that have shown promising outcomes in basic research(in vivo animal studies) and clinical trials: AA-NgR(310)ecto-Fc(AXER-204), fasudil, phosphatase and tensin homolog protein antagonist peptide 4, chondroitinase ABC, intracellular sigma peptide,(-)-epigallocatechin gallate, matrine, acteoside, pyrvate kinase M2, diosgenin, granulocyte-colony stimulating factor, and fampridine-sustained release. Although the current situation suggests that drug-based therapies to recover function in chronic spinal cord injury are limited, potential candidates have been identified through basic research, and these candidates may be subjects of clinical studies in the future. Moreover, cocktail therapy comprising drugs with varied underlying mechanisms may be effective in treating the refractory status of chronic spinal cord injury.
