Based on BERTopic Model,the paper combines qualitative and quantitative methods to explore the reception of Can Xue’s translated works by analyzing readers’book reviews posted on Goodreads and Lovereading.We first c...Based on BERTopic Model,the paper combines qualitative and quantitative methods to explore the reception of Can Xue’s translated works by analyzing readers’book reviews posted on Goodreads and Lovereading.We first collected book reviews from these two well-known websites by Python.Through topic analysis of these reviews,we identified recurring topics,including details of her translated works and appreciation of their translation quality.Then,employing sentiment and content analysis methods,the paper explored the emotional attitudes and the specific thoughts of readers toward Can Xue and her translated works.The fingdings revealed that,among the 408 reviews,though the reception of Can Xue’s translated works was relatively positive,the current level of attention and recognition remains insufficient.However,based on the research results,the paper can derive valuable insights into the translation and dissemination processes such as adjusting translation and dissemination strategies,so that the global reach of Chinese literature and culture can be better facilitated.展开更多
Weak signal reception is a very important and challenging problem for communication systems especially in the presence of non-Gaussian noise,and in which case the performance of optimal linear correlated receiver degr...Weak signal reception is a very important and challenging problem for communication systems especially in the presence of non-Gaussian noise,and in which case the performance of optimal linear correlated receiver degrades dramatically.Aiming at this,a novel uncorrelated reception scheme based on adaptive bistable stochastic resonance(ABSR)for a weak signal in additive Laplacian noise is investigated.By analyzing the key issue that the quantitative cooperative resonance matching relationship between the characteristics of the noisy signal and the nonlinear bistable system,an analytical expression of the bistable system parameters is derived.On this basis,by means of bistable system parameters self-adaptive adjustment,the counterintuitive stochastic resonance(SR)phenomenon can be easily generated at which the random noise is changed into a benefit to assist signal transmission.Finally,it is demonstrated that approximately 8dB bit error ratio(BER)performance improvement for the ABSR-based uncorrelated receiver when compared with the traditional uncorrelated receiver at low signal to noise ratio(SNR)conditions varying from-30dB to-5dB.展开更多
Introduction The main objective of any healthcare establishment must be to ensure the quality of patient care and customer satisfaction. It is necessary to regularly assess patient satisfaction. The aim of this study ...Introduction The main objective of any healthcare establishment must be to ensure the quality of patient care and customer satisfaction. It is necessary to regularly assess patient satisfaction. The aim of this study was to assess the level of satisfaction of customers aged over 18 years attending the emergency department of the health center. Methodology This was a descriptive and analytical cross-sectional study of patients aged 18 years and over, who attended the Samu Municipal emergency department between 02 and 30 May 2023. The satisfaction index was determined using the adapted 2009 SAPHORA-MCO questionnaire and the Likert satisfaction scale. Results A total of 400 patients were surveyed. The average age was 35 years, with a standard deviation of 14.7. Of those surveyed, 51% were women, 87% were educated, 50% lived in Grand Yoff and 59.5% were unemployed. Satisfaction levels linked to perception of the cost of care (72%), waiting time (64.3%), information given to patients (69.1%) and pain management (74 .5%) are fair. On the other hand, the levels of satisfaction linked to administrative procedures (82.5%), staff attitudes towards patients (84%), staff availability (86.4%), patient privacy (89.2%), general atmosphere (87.2%), staff competence (87.3%), and the effectiveness of care (89.4%) were satisfactory. The average waiting time was 38 minutes. However, 32% of patients waited less than 30 minutes and 92% less than an hour. The satisfaction index linked to administration and reception was 72.9% and 79.85%, respectively. The satisfaction index linked to the administration and technical quality of care is equal to 85.8% and 83.7%, respectively. The overall satisfaction index is equal to 80.6%;the level of satisfaction of users of the health structure is satisfactory. Conclusion Patient satisfaction is an essential part of quality care. Patient satisfaction must be based on effective communication from the healthcare team and the creation of a patient-caregiver relationship.展开更多
Good translations play a very important role in cultural exchange.The idea of reception aesthetics think the reader as the center in translation process.This paper will study the translation of culture-loaded words fr...Good translations play a very important role in cultural exchange.The idea of reception aesthetics think the reader as the center in translation process.This paper will study the translation of culture-loaded words from the perspective of reception aesthetics.It is divided into five parts.The first part mainly introduces the background and theoretical foundation of this paper,the second part introduces the writer’s works,the third part gives examples to analyze the culture-loaded words appearing in The Golden Cangue,the fourth part gives examples of the translation methods,and the fifth part is the conclusion.It aims to provide a reference for the English translation of culture-loaded words.展开更多
Grounded in reader-centered theories,Reception Aesthetics prioritizes the active engagement and acceptance of target readers.This study examines the translation of children’s literature through the lens of Reception ...Grounded in reader-centered theories,Reception Aesthetics prioritizes the active engagement and acceptance of target readers.This study examines the translation of children’s literature through the lens of Reception Aesthetics,using Li Wenjun’s rendition of The Secret Garden as a case study.The objective is to scrutinize various aspects of the translation-including vocabulary,syntax,rhetorical devices,and cultural nuances-and to discern how the adaptation and application of diverse translation strategies cater to the aesthetic expectations.展开更多
Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effec...Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effect of sow backfat thickness on litter size is associated with endometrial receptivity and whether melatonin treatment may have benefits.The present study seeks to answer these questions through in vitro and in vivo investigations.Results Excessive lipid deposition and lower melatonin levels in the uterus are detrimental to endometrial receptivity and embryo implantation in high backfat thickness sows.In cells treated with melatonin,the MT2/PI3K/LIF axis played a role in reducing lipid accumulation in porcine endometrial epithelium cells and improved endometrial receptivity.Furthermore,we found a reduction of lipids in the uterus after eight weeks of intraperitoneal administration of melatonin to HFD mice.Notably,melatonin treatment caused a significant reduction in the deposition of endometrial collagen,an increase in the number of glands,and repair of the pinopode structure,ultimately improving endometrial receptivity,promoting embryo implantation,and increasing the number of litter size of mice.Conclusions Collectively,the finding reveals the harmful effects of high backfat thickness sows on embryo implantation and highlight the role of melatonin and the MT2/PI3K/LIF axis in improving endometrial receptivity by enhancing metabolism and reducing the levels of uterine lipids in obese animals.展开更多
Hypersonic boundary-layer receptivity to freestream entropy and vorticity waves is investigated using direct numerical simula-tions for a Mach 6 flow over a 5.08 mm nose radius cone.Two frequencies of 33 kHz and 150 k...Hypersonic boundary-layer receptivity to freestream entropy and vorticity waves is investigated using direct numerical simula-tions for a Mach 6 flow over a 5.08 mm nose radius cone.Two frequencies of 33 kHz and 150 kHz are considered to be rep-resentative of the first and second instability modes,respectively.For the first mode,wall pressure fluctuations for both entropy and vorticity wave cases exhibit a strong modulation yet without a growing trend,indicating that the first mode is not generated despite its instability predicted by linear stability theory.The potential reason for this is the absence of postshock slow acoustic waves capable of synchronizing with the first mode.By contrast,for the second mode,a typical three-stage boundary-layer response is observed,consistent with that to slow acoustic waves studied previously.Furthermore,the postshock disturbances outside the boundary layer can be decomposed into the entropy(density/temperature fluctuations)and vorticity components(ve-locity fluctuations),and the latter is shown to play a leading role in generating the second mode,even for the case with entropy waves where the density/temperature fluctuations dominate the postshock regions.展开更多
Objective:This study aimed to explore the clinical effect of acupuncture therapy for menstruation regu-lation and pregnancy promotion on thin endometrium in the real world.Design:This study is a single-center pragmati...Objective:This study aimed to explore the clinical effect of acupuncture therapy for menstruation regu-lation and pregnancy promotion on thin endometrium in the real world.Design:This study is a single-center pragmatic randomized controlled trial blinded to the statisticians.Using the“blockrand”software package,based on the age(≥35,<35),37 patients were randomized into an intervention group(19 cases)and a control group(18 cases).After reassignment regarding patient preference,21 patients were included in the intervention group and 16 in the control group.Setting:The trial was executed in the Specialty Outpatient Clinic,Acupuncture-Moxibustion Hospital of China Academy of Chinese Medical Sciences,from March 1,2019,to September 30,2020.Participants:The study included 37 patients with thin endometrium and without previous acupuncture treatment.Intervention:The intervention group was administered acupuncture for menstruation regulation and pregnancy promotion and a small-dose of progynova(2 mg daily),while the control group was adminis-tered a large-dose of progynova(4 mg daily).Interventions started from Day 5 of menstruation until the end of ovulation under B-ultrasound monitoring.The intervention lasted for three menstrual cycles.Measurements:Primary outcomes were changes in endometrial thickness between baseline and after intervention completion and the difference between the two groups after intervention.The secondary outcomes were endometrial and subendometrial blood flow,serum estradiol levels,menstrual conditions,and adverse reactions.Results:(1)Comparison of each indicator before and after intervention completion in the two groups:in the intervention group,the differences were significant in endometrial thickness,menstrual score,estra-diol(E2)level in ovulatory period,the pulsatility index(PI)and resistance index(RI)of uterine artery,the ratio of peak systolic velocity to end-diastolic velocity(S/D),the endometrial vascular index(VI),flow index(FI),and vascular flow index(VFI)and volume(P<0.01).In the control group,significant changes were observed in endometrial thickness,menstrual score,and E2 before and after the interven-tion(P<0.05),and no differences were observed in uterine artery PI,RI,S/D and endometrial VI,FI,VFI,and volume(P>0.05).Compared with the control group,the intervention group showed significant differences in endometrial thickness,menstrual score,E2,uterine artery PI,RI,S/D,and endometrial VI,FI,VFI,and volume after intervention(P<0.01).No adverse reactions were reported in the intervention group.In contrast,the control group had two cases of nausea and gastrointestinal discomfort after med-ication,eight cases of breast distention during medication,and one case of breast nodules enlarged by 1 cm after trial completion.展开更多
BACKGROUND Despite advances in the use of in vitro fertilization-embryo transfer(ET)in couples with infertility,recurrent implantation failure(RIF)after ET is still a major problem affecting women,with great psycholog...BACKGROUND Despite advances in the use of in vitro fertilization-embryo transfer(ET)in couples with infertility,recurrent implantation failure(RIF)after ET is still a major problem affecting women,with great psychological and economic burdens for the patient and his/her family.AIM To investigate the psychological burden(anxiety and depression)and evaluate the clinical benefits of endometrial receptivity testing(ERT)in patients experiencing RIF following frozen-thawed ET.METHODS A retrospective cohort study analyzed 371 patients experiencing RIF after assisted reproductive treatment at the First People’s Hospital of Changde City between January 2021 and June 2024.Demographic and clinical data were systematically collected through standardized questionnaires.Psychological assessment utilized validated instruments:The Self-Rating Depression Scale for depression evaluation and the Self-Rating Anxiety Scale for anxiety assessment.Participants were stratified by psychological status(anxiety/non-anxiety and depression/nondepression)to analyze influencing factors for anxiety and depression.The cohort was further categorized into the ERT and non-ERT groups based on ERT implementation to comparatively analyze their clinical outcomes.Additionally,they were divided into clinical and nonclinical pregnancy groups to identify factors affecting clinical pregnancy using univariate and multivariate logistic regression models.Compared with the non-ERT group,the 226 patients who underwent ERT-guided ET achieved a higher clinical pregnancy rate,thicker endometrium on transfer day,fewer embryos transferred,and a lower miscarriage rate.RESULTS The study identified a substantial psychological burden,with anxiety prevalence at 55.0%(mean Self-Rating Anxiety Scale score,50.89±9.34)and depression at 61.2%(mean Self-Rating Depression Scale score,55.55±9.48).Multivariate analysis identified annual household income>100000 yuan as protective factors against both anxiety and depression,whereas advanced maternal age(>35 years)and multiple implantation failures(≥3)served as risk factors.Additionally,anxiety-specific risk factors included prolonged infertility treatment(>5 years)and the spouse’s status as an only child.As to depression-specific risks,chronic infertility(>3 years)and higher educational attainment(college/bachelor’s degree or higher)were key determinants,whereas urban residence was a protective factor.Age>35 years was a risk factor for clinical pregnancy in patients experiencing RIF,whereas blastocyst-stage ET,a higher number of embryos transferred,and thicker endometrium were protective factors.CONCLUSION Patients experiencing RIF are particularly susceptible to anxiety and depression,and advanced maternal age and multiple implantation failures represent salient risk factors.Clinicians should implement proactive and evidencebased interventions to mitigate these psychological burdens.For patients experiencing RIF,ERT-guided ET demonstrates significant potential to improve assisted reproductive outcomes.展开更多
Drone-based small object detection is of great significance in practical applications such as military actions, disaster rescue, transportation, etc. However, the severe scale differences in objects captured by drones...Drone-based small object detection is of great significance in practical applications such as military actions, disaster rescue, transportation, etc. However, the severe scale differences in objects captured by drones and lack of detail information for small-scale objects make drone-based small object detection a formidable challenge. To address these issues, we first develop a mathematical model to explore how changing receptive fields impacts the polynomial fitting results. Subsequently, based on the obtained conclusions, we propose a simple but effective Hybrid Receptive Field Network (HRFNet), whose modules include Hybrid Feature Augmentation (HFA), Hybrid Feature Pyramid (HFP) and Dual Scale Head (DSH). Specifically, HFA employs parallel dilated convolution kernels of different sizes to extend shallow features with different receptive fields, committed to improving the multi-scale adaptability of the network;HFP enhances the perception of small objects by capturing contextual information across layers, while DSH reconstructs the original prediction head utilizing a set of high-resolution features and ultrahigh-resolution features. In addition, in order to train HRFNet, the corresponding dual-scale loss function is designed. Finally, comprehensive evaluation results on public benchmarks such as VisDrone-DET and TinyPerson demonstrate the robustness of the proposed method. Most impressively, the proposed HRFNet achieves a mAP of 51.0 on VisDrone-DET with 29.3 M parameters, which outperforms the extant state-of-the-art detectors. HRFNet also performs excellently in complex scenarios captured by drones, achieving the best performance on the CS-Drone dataset we built.展开更多
In recent years,a great majority of excellent foreign children' s literary works have sprung up in the domestic market,so the translation of children' literature are drawn much attention.However,the relevant s...In recent years,a great majority of excellent foreign children' s literary works have sprung up in the domestic market,so the translation of children' literature are drawn much attention.However,the relevant studies which guide the translation of children literature are quite few.Reception Aesthetics which take readers reception as a goal provides a new prospective for the translation of children s literature and promote its development.展开更多
In literary translation,creative treason or translation deviations will surely be a shadow in company with each translated work.A translator is both the reader of the source text and the producer of the target text.Ap...In literary translation,creative treason or translation deviations will surely be a shadow in company with each translated work.A translator is both the reader of the source text and the producer of the target text.Applying much on Reception Theory,the present paper explores the issue of translator's creative treason in literary translation in two aspects:one is the translator's creative treason as reader and the other is the translator's creative treason as producer.展开更多
Drawing upon the theory of reception aesthetics, this dissertation aims to discuss the translator's translation of You Can YouWill. Beginning with preliminary background information, e.g. the source book and write...Drawing upon the theory of reception aesthetics, this dissertation aims to discuss the translator's translation of You Can YouWill. Beginning with preliminary background information, e.g. the source book and writer, the translator further introduces theories andprevious related research, including Christian work. There are two representatives of reception theory; the translator stresses Jauss' per-spective of reception aesthetics, detailing his two key notions: the reader's decisive role and horizon of expectation. These notions shiftthe focus from the writer and text to the reader, which is a proven method to make the translation more acceptable to readers. Based onthe translation brief, target readers are Christians. During the translation process, the translator keeps key notions of reception aestheticstop-of-mind and strives to produce a version suitable for Christian readers. Some strategies, e.g. domestication and footnoting, are em-ployed to discuss the translation of biblical terms, Christian expressions, verses or stories from the Bible, metaphors and cultural items.In addition to these strategies, all translation is in accordance with CUV when encountering Bible-related text, due to CUV's authorityamong all versions of the Bible. Lastly, the translator provides conclusive remarks based on analysis as well as suggestions for further re-search. Limitations of this study are also mentioned.展开更多
The subtitle translation not only needs to consider the audience’s horizon of expectation and acceptability,but also has to achieve the significance of spreading Chinese culture to foreigners.This paper explores the ...The subtitle translation not only needs to consider the audience’s horizon of expectation and acceptability,but also has to achieve the significance of spreading Chinese culture to foreigners.This paper explores the rules,principles and methods of the subtitle translation of Chinese films from the perspective of reception aesthetics.展开更多
Reception theory stresses reader's activeness.Translation of Chinese Menu in English Version reveals the universal principles of transnational strategies and methods of menu translation.Through analysis of Chinese...Reception theory stresses reader's activeness.Translation of Chinese Menu in English Version reveals the universal principles of transnational strategies and methods of menu translation.Through analysis of Chinese Menu in English Version,the article studies its text and examines the linking mechanism between reception theory and menu translation.A comparative conclusion shows that in menu translation attention is paid to the accuracy of the target text by translators,who are simultaneously aware of the paradox between expectation and acceptance of individual readers.展开更多
This paper discusses three similaritie"s:Gap"Structure and the Fictitious Realm, the reader's active role in the realization of the meaning, gestalt formation between the Reception Aesthetics and the Art...This paper discusses three similaritie"s:Gap"Structure and the Fictitious Realm, the reader's active role in the realization of the meaning, gestalt formation between the Reception Aesthetics and the Artistic Ideorealm Theory.展开更多
According to aesthetics of reception, the reception of literature can be divided into two patterns, that is, vertical reception and horizontal reception. The former means determining the original text＇s meaning from ...According to aesthetics of reception, the reception of literature can be divided into two patterns, that is, vertical reception and horizontal reception. The former means determining the original text＇s meaning from the perspective of historical development. Readers in different history periods have different explanations and conclusions of certain writer or original text because of their different social and cultural backgrounds. The author of this thesis combines the viewpoint and the translation of famous book, holding that famous book has special aesthetical value and its explanation shouldn＇t be limited by certain translated version. Retranslation can keep and enrich the aesthetical value of the famous book and should be encouraged.展开更多
Based on the acoustic radiation theory of a dipole source, the influence of the transducer reception pattern is studied for magnetoacoustic tomography with magnetic induction（MAT-MI）. Numerical studies are conducted...Based on the acoustic radiation theory of a dipole source, the influence of the transducer reception pattern is studied for magnetoacoustic tomography with magnetic induction（MAT-MI）. Numerical studies are conducted to simulate acoustic pressures, waveforms, and reconstructed images with unidirectional, omnidirectional, and strong directional transducers.With the analyses of equivalent and projection sources, the influences of the model dimension and the layer effect are qualitatively analyzed to evaluate the performance of MAT-MI. Three-dimensional simulation studies show that the strong directional transducer with a large radius can reduce the influences of equivalent sources, projection sources, and the layer effect effectively, resulting in enhanced pressure and improved image contrast, which is beneficial for boundary pressure extraction in conductivity reconstruction. The reconstructed conductivity contrast images present the conductivity boundaries as stripes with different contrasts and polarities, representing the values and directions of the conductivity changes of the scanned layer. The favorable results provide solid evidence for transducer selection and suggest potential practical applications of MAT-MI in biomedical imaging.展开更多
基金supported by the 2023 Youth Fund for Humanities and Social Sciences Research by the Ministry of Education of the People’s Republic of China(Grant No.23YJC740004).
文摘Based on BERTopic Model,the paper combines qualitative and quantitative methods to explore the reception of Can Xue’s translated works by analyzing readers’book reviews posted on Goodreads and Lovereading.We first collected book reviews from these two well-known websites by Python.Through topic analysis of these reviews,we identified recurring topics,including details of her translated works and appreciation of their translation quality.Then,employing sentiment and content analysis methods,the paper explored the emotional attitudes and the specific thoughts of readers toward Can Xue and her translated works.The fingdings revealed that,among the 408 reviews,though the reception of Can Xue’s translated works was relatively positive,the current level of attention and recognition remains insufficient.However,based on the research results,the paper can derive valuable insights into the translation and dissemination processes such as adjusting translation and dissemination strategies,so that the global reach of Chinese literature and culture can be better facilitated.
基金supported in part by the National Natural Science Foundation of China(62001356)in part by the National Natural Science Foundation for Distinguished Young Scholar(61825104)+1 种基金in part by the National Key Research and Development Program of China(2022YFC3301300)in part by the Innovative Research Groups of the National Natural Science Foundation of China(62121001)。
文摘Weak signal reception is a very important and challenging problem for communication systems especially in the presence of non-Gaussian noise,and in which case the performance of optimal linear correlated receiver degrades dramatically.Aiming at this,a novel uncorrelated reception scheme based on adaptive bistable stochastic resonance(ABSR)for a weak signal in additive Laplacian noise is investigated.By analyzing the key issue that the quantitative cooperative resonance matching relationship between the characteristics of the noisy signal and the nonlinear bistable system,an analytical expression of the bistable system parameters is derived.On this basis,by means of bistable system parameters self-adaptive adjustment,the counterintuitive stochastic resonance(SR)phenomenon can be easily generated at which the random noise is changed into a benefit to assist signal transmission.Finally,it is demonstrated that approximately 8dB bit error ratio(BER)performance improvement for the ABSR-based uncorrelated receiver when compared with the traditional uncorrelated receiver at low signal to noise ratio(SNR)conditions varying from-30dB to-5dB.
文摘Introduction The main objective of any healthcare establishment must be to ensure the quality of patient care and customer satisfaction. It is necessary to regularly assess patient satisfaction. The aim of this study was to assess the level of satisfaction of customers aged over 18 years attending the emergency department of the health center. Methodology This was a descriptive and analytical cross-sectional study of patients aged 18 years and over, who attended the Samu Municipal emergency department between 02 and 30 May 2023. The satisfaction index was determined using the adapted 2009 SAPHORA-MCO questionnaire and the Likert satisfaction scale. Results A total of 400 patients were surveyed. The average age was 35 years, with a standard deviation of 14.7. Of those surveyed, 51% were women, 87% were educated, 50% lived in Grand Yoff and 59.5% were unemployed. Satisfaction levels linked to perception of the cost of care (72%), waiting time (64.3%), information given to patients (69.1%) and pain management (74 .5%) are fair. On the other hand, the levels of satisfaction linked to administrative procedures (82.5%), staff attitudes towards patients (84%), staff availability (86.4%), patient privacy (89.2%), general atmosphere (87.2%), staff competence (87.3%), and the effectiveness of care (89.4%) were satisfactory. The average waiting time was 38 minutes. However, 32% of patients waited less than 30 minutes and 92% less than an hour. The satisfaction index linked to administration and reception was 72.9% and 79.85%, respectively. The satisfaction index linked to the administration and technical quality of care is equal to 85.8% and 83.7%, respectively. The overall satisfaction index is equal to 80.6%;the level of satisfaction of users of the health structure is satisfactory. Conclusion Patient satisfaction is an essential part of quality care. Patient satisfaction must be based on effective communication from the healthcare team and the creation of a patient-caregiver relationship.
文摘Good translations play a very important role in cultural exchange.The idea of reception aesthetics think the reader as the center in translation process.This paper will study the translation of culture-loaded words from the perspective of reception aesthetics.It is divided into five parts.The first part mainly introduces the background and theoretical foundation of this paper,the second part introduces the writer’s works,the third part gives examples to analyze the culture-loaded words appearing in The Golden Cangue,the fourth part gives examples of the translation methods,and the fifth part is the conclusion.It aims to provide a reference for the English translation of culture-loaded words.
文摘Grounded in reader-centered theories,Reception Aesthetics prioritizes the active engagement and acceptance of target readers.This study examines the translation of children’s literature through the lens of Reception Aesthetics,using Li Wenjun’s rendition of The Secret Garden as a case study.The objective is to scrutinize various aspects of the translation-including vocabulary,syntax,rhetorical devices,and cultural nuances-and to discern how the adaptation and application of diverse translation strategies cater to the aesthetic expectations.
基金supported by the China Agriculture Research System(CARS-35-PIG)the National Natural Science Foundation of China(32272847,U22A20516)+1 种基金the National Key Research and Development Program of China(No.2021YFF1000602)the Key Research and Development Program of Shaanxi Province(No.2022ZDLNY01–04)。
文摘Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effect of sow backfat thickness on litter size is associated with endometrial receptivity and whether melatonin treatment may have benefits.The present study seeks to answer these questions through in vitro and in vivo investigations.Results Excessive lipid deposition and lower melatonin levels in the uterus are detrimental to endometrial receptivity and embryo implantation in high backfat thickness sows.In cells treated with melatonin,the MT2/PI3K/LIF axis played a role in reducing lipid accumulation in porcine endometrial epithelium cells and improved endometrial receptivity.Furthermore,we found a reduction of lipids in the uterus after eight weeks of intraperitoneal administration of melatonin to HFD mice.Notably,melatonin treatment caused a significant reduction in the deposition of endometrial collagen,an increase in the number of glands,and repair of the pinopode structure,ultimately improving endometrial receptivity,promoting embryo implantation,and increasing the number of litter size of mice.Conclusions Collectively,the finding reveals the harmful effects of high backfat thickness sows on embryo implantation and highlight the role of melatonin and the MT2/PI3K/LIF axis in improving endometrial receptivity by enhancing metabolism and reducing the levels of uterine lipids in obese animals.
基金supported by the National Natural Science Foundation of China(GrantNo.12072231).
文摘Hypersonic boundary-layer receptivity to freestream entropy and vorticity waves is investigated using direct numerical simula-tions for a Mach 6 flow over a 5.08 mm nose radius cone.Two frequencies of 33 kHz and 150 kHz are considered to be rep-resentative of the first and second instability modes,respectively.For the first mode,wall pressure fluctuations for both entropy and vorticity wave cases exhibit a strong modulation yet without a growing trend,indicating that the first mode is not generated despite its instability predicted by linear stability theory.The potential reason for this is the absence of postshock slow acoustic waves capable of synchronizing with the first mode.By contrast,for the second mode,a typical three-stage boundary-layer response is observed,consistent with that to slow acoustic waves studied previously.Furthermore,the postshock disturbances outside the boundary layer can be decomposed into the entropy(density/temperature fluctuations)and vorticity components(ve-locity fluctuations),and the latter is shown to play a leading role in generating the second mode,even for the case with entropy waves where the density/temperature fluctuations dominate the postshock regions.
基金Supported by Special Funds for Basic Scientific Research of Central Public Welfare Research Institutes:201814006。
文摘Objective:This study aimed to explore the clinical effect of acupuncture therapy for menstruation regu-lation and pregnancy promotion on thin endometrium in the real world.Design:This study is a single-center pragmatic randomized controlled trial blinded to the statisticians.Using the“blockrand”software package,based on the age(≥35,<35),37 patients were randomized into an intervention group(19 cases)and a control group(18 cases).After reassignment regarding patient preference,21 patients were included in the intervention group and 16 in the control group.Setting:The trial was executed in the Specialty Outpatient Clinic,Acupuncture-Moxibustion Hospital of China Academy of Chinese Medical Sciences,from March 1,2019,to September 30,2020.Participants:The study included 37 patients with thin endometrium and without previous acupuncture treatment.Intervention:The intervention group was administered acupuncture for menstruation regulation and pregnancy promotion and a small-dose of progynova(2 mg daily),while the control group was adminis-tered a large-dose of progynova(4 mg daily).Interventions started from Day 5 of menstruation until the end of ovulation under B-ultrasound monitoring.The intervention lasted for three menstrual cycles.Measurements:Primary outcomes were changes in endometrial thickness between baseline and after intervention completion and the difference between the two groups after intervention.The secondary outcomes were endometrial and subendometrial blood flow,serum estradiol levels,menstrual conditions,and adverse reactions.Results:(1)Comparison of each indicator before and after intervention completion in the two groups:in the intervention group,the differences were significant in endometrial thickness,menstrual score,estra-diol(E2)level in ovulatory period,the pulsatility index(PI)and resistance index(RI)of uterine artery,the ratio of peak systolic velocity to end-diastolic velocity(S/D),the endometrial vascular index(VI),flow index(FI),and vascular flow index(VFI)and volume(P<0.01).In the control group,significant changes were observed in endometrial thickness,menstrual score,and E2 before and after the interven-tion(P<0.05),and no differences were observed in uterine artery PI,RI,S/D and endometrial VI,FI,VFI,and volume(P>0.05).Compared with the control group,the intervention group showed significant differences in endometrial thickness,menstrual score,E2,uterine artery PI,RI,S/D,and endometrial VI,FI,VFI,and volume after intervention(P<0.01).No adverse reactions were reported in the intervention group.In contrast,the control group had two cases of nausea and gastrointestinal discomfort after med-ication,eight cases of breast distention during medication,and one case of breast nodules enlarged by 1 cm after trial completion.
文摘BACKGROUND Despite advances in the use of in vitro fertilization-embryo transfer(ET)in couples with infertility,recurrent implantation failure(RIF)after ET is still a major problem affecting women,with great psychological and economic burdens for the patient and his/her family.AIM To investigate the psychological burden(anxiety and depression)and evaluate the clinical benefits of endometrial receptivity testing(ERT)in patients experiencing RIF following frozen-thawed ET.METHODS A retrospective cohort study analyzed 371 patients experiencing RIF after assisted reproductive treatment at the First People’s Hospital of Changde City between January 2021 and June 2024.Demographic and clinical data were systematically collected through standardized questionnaires.Psychological assessment utilized validated instruments:The Self-Rating Depression Scale for depression evaluation and the Self-Rating Anxiety Scale for anxiety assessment.Participants were stratified by psychological status(anxiety/non-anxiety and depression/nondepression)to analyze influencing factors for anxiety and depression.The cohort was further categorized into the ERT and non-ERT groups based on ERT implementation to comparatively analyze their clinical outcomes.Additionally,they were divided into clinical and nonclinical pregnancy groups to identify factors affecting clinical pregnancy using univariate and multivariate logistic regression models.Compared with the non-ERT group,the 226 patients who underwent ERT-guided ET achieved a higher clinical pregnancy rate,thicker endometrium on transfer day,fewer embryos transferred,and a lower miscarriage rate.RESULTS The study identified a substantial psychological burden,with anxiety prevalence at 55.0%(mean Self-Rating Anxiety Scale score,50.89±9.34)and depression at 61.2%(mean Self-Rating Depression Scale score,55.55±9.48).Multivariate analysis identified annual household income>100000 yuan as protective factors against both anxiety and depression,whereas advanced maternal age(>35 years)and multiple implantation failures(≥3)served as risk factors.Additionally,anxiety-specific risk factors included prolonged infertility treatment(>5 years)and the spouse’s status as an only child.As to depression-specific risks,chronic infertility(>3 years)and higher educational attainment(college/bachelor’s degree or higher)were key determinants,whereas urban residence was a protective factor.Age>35 years was a risk factor for clinical pregnancy in patients experiencing RIF,whereas blastocyst-stage ET,a higher number of embryos transferred,and thicker endometrium were protective factors.CONCLUSION Patients experiencing RIF are particularly susceptible to anxiety and depression,and advanced maternal age and multiple implantation failures represent salient risk factors.Clinicians should implement proactive and evidencebased interventions to mitigate these psychological burdens.For patients experiencing RIF,ERT-guided ET demonstrates significant potential to improve assisted reproductive outcomes.
基金supported by the National Natural Science Foundation of China(Nos.62276204 and 62203343)the Fundamental Research Funds for the Central Universities(No.YJSJ24011)+1 种基金the Natural Science Basic Research Program of Shanxi,China(Nos.2022JM-340 and 2023-JC-QN-0710)the China Postdoctoral Science Foundation(Nos.2020T130494 and 2018M633470).
文摘Drone-based small object detection is of great significance in practical applications such as military actions, disaster rescue, transportation, etc. However, the severe scale differences in objects captured by drones and lack of detail information for small-scale objects make drone-based small object detection a formidable challenge. To address these issues, we first develop a mathematical model to explore how changing receptive fields impacts the polynomial fitting results. Subsequently, based on the obtained conclusions, we propose a simple but effective Hybrid Receptive Field Network (HRFNet), whose modules include Hybrid Feature Augmentation (HFA), Hybrid Feature Pyramid (HFP) and Dual Scale Head (DSH). Specifically, HFA employs parallel dilated convolution kernels of different sizes to extend shallow features with different receptive fields, committed to improving the multi-scale adaptability of the network;HFP enhances the perception of small objects by capturing contextual information across layers, while DSH reconstructs the original prediction head utilizing a set of high-resolution features and ultrahigh-resolution features. In addition, in order to train HRFNet, the corresponding dual-scale loss function is designed. Finally, comprehensive evaluation results on public benchmarks such as VisDrone-DET and TinyPerson demonstrate the robustness of the proposed method. Most impressively, the proposed HRFNet achieves a mAP of 51.0 on VisDrone-DET with 29.3 M parameters, which outperforms the extant state-of-the-art detectors. HRFNet also performs excellently in complex scenarios captured by drones, achieving the best performance on the CS-Drone dataset we built.
文摘In recent years,a great majority of excellent foreign children' s literary works have sprung up in the domestic market,so the translation of children' literature are drawn much attention.However,the relevant studies which guide the translation of children literature are quite few.Reception Aesthetics which take readers reception as a goal provides a new prospective for the translation of children s literature and promote its development.
文摘In literary translation,creative treason or translation deviations will surely be a shadow in company with each translated work.A translator is both the reader of the source text and the producer of the target text.Applying much on Reception Theory,the present paper explores the issue of translator's creative treason in literary translation in two aspects:one is the translator's creative treason as reader and the other is the translator's creative treason as producer.
文摘Drawing upon the theory of reception aesthetics, this dissertation aims to discuss the translator's translation of You Can YouWill. Beginning with preliminary background information, e.g. the source book and writer, the translator further introduces theories andprevious related research, including Christian work. There are two representatives of reception theory; the translator stresses Jauss' per-spective of reception aesthetics, detailing his two key notions: the reader's decisive role and horizon of expectation. These notions shiftthe focus from the writer and text to the reader, which is a proven method to make the translation more acceptable to readers. Based onthe translation brief, target readers are Christians. During the translation process, the translator keeps key notions of reception aestheticstop-of-mind and strives to produce a version suitable for Christian readers. Some strategies, e.g. domestication and footnoting, are em-ployed to discuss the translation of biblical terms, Christian expressions, verses or stories from the Bible, metaphors and cultural items.In addition to these strategies, all translation is in accordance with CUV when encountering Bible-related text, due to CUV's authorityamong all versions of the Bible. Lastly, the translator provides conclusive remarks based on analysis as well as suggestions for further re-search. Limitations of this study are also mentioned.
文摘The subtitle translation not only needs to consider the audience’s horizon of expectation and acceptability,but also has to achieve the significance of spreading Chinese culture to foreigners.This paper explores the rules,principles and methods of the subtitle translation of Chinese films from the perspective of reception aesthetics.
文摘Reception theory stresses reader's activeness.Translation of Chinese Menu in English Version reveals the universal principles of transnational strategies and methods of menu translation.Through analysis of Chinese Menu in English Version,the article studies its text and examines the linking mechanism between reception theory and menu translation.A comparative conclusion shows that in menu translation attention is paid to the accuracy of the target text by translators,who are simultaneously aware of the paradox between expectation and acceptance of individual readers.
文摘This paper discusses three similaritie"s:Gap"Structure and the Fictitious Realm, the reader's active role in the realization of the meaning, gestalt formation between the Reception Aesthetics and the Artistic Ideorealm Theory.
文摘According to aesthetics of reception, the reception of literature can be divided into two patterns, that is, vertical reception and horizontal reception. The former means determining the original text＇s meaning from the perspective of historical development. Readers in different history periods have different explanations and conclusions of certain writer or original text because of their different social and cultural backgrounds. The author of this thesis combines the viewpoint and the translation of famous book, holding that famous book has special aesthetical value and its explanation shouldn＇t be limited by certain translated version. Retranslation can keep and enrich the aesthetical value of the famous book and should be encouraged.
基金Project supported by the National Basic Research Program of China(Grant No.2011CB707900)the National Natural Science Foundation of China(Grant Nos 11274176 and 11474166)the Priority Academic Program Development of Jiangsu Higher Education Institutions,China
文摘Based on the acoustic radiation theory of a dipole source, the influence of the transducer reception pattern is studied for magnetoacoustic tomography with magnetic induction（MAT-MI）. Numerical studies are conducted to simulate acoustic pressures, waveforms, and reconstructed images with unidirectional, omnidirectional, and strong directional transducers.With the analyses of equivalent and projection sources, the influences of the model dimension and the layer effect are qualitatively analyzed to evaluate the performance of MAT-MI. Three-dimensional simulation studies show that the strong directional transducer with a large radius can reduce the influences of equivalent sources, projection sources, and the layer effect effectively, resulting in enhanced pressure and improved image contrast, which is beneficial for boundary pressure extraction in conductivity reconstruction. The reconstructed conductivity contrast images present the conductivity boundaries as stripes with different contrasts and polarities, representing the values and directions of the conductivity changes of the scanned layer. The favorable results provide solid evidence for transducer selection and suggest potential practical applications of MAT-MI in biomedical imaging.
