Reliability enhancement testing(RET) is an accelerated testing which hastens the performance degradation process to surface its inherent defects of design and manufacture. It is an important hypothesis that the degrad...Reliability enhancement testing(RET) is an accelerated testing which hastens the performance degradation process to surface its inherent defects of design and manufacture. It is an important hypothesis that the degradation mechanism of the RET is the same as the one of the normal stress condition. In order to check the consistency of two mechanisms, we conduct two enhancement tests with a missile servo system as an object of the study, and preprocess two sets of test data to establish the accelerated degradation models regarding the temperature change rate that is assumed to be the main applied stress of the servo system during the natural storage. Based on the accelerated degradation models and natural storage profile of the servo system, we provide and demonstrate a procedure to check the consistency of two mechanisms by checking the correlation and difference of two sets of degradation data. The results indicate that the two degradation mechanisms are significantly consistent with each other.展开更多
Blockchain is a technology that provides security features that can be used for more than just cryptocurrencies.Blockchain achieves security by saving the information of one block in the next block.Changing the inform...Blockchain is a technology that provides security features that can be used for more than just cryptocurrencies.Blockchain achieves security by saving the information of one block in the next block.Changing the information of one block will require changes to all the next block in order for that change to take effect.Which makes it unfeasible for such an attack to happen.However,the structure of how blockchain works makes the last block always vulnerable for attacks,given that its information is not saved yet in any block.This allows malicious node to change the information of the last block and generate a new block and broadcast it to the network.Given that the nodes always follow the longer chain wins rule,the malicious node will win given that it has the longest chain in the network.This paper suggests a solution to this issue by making the nodes send consistency check messages before broadcasting a block.If the nodes manage to successfully verify that the node that generated a new block hasn’t tampered with the blockchain than that block will be broadcasted.The results of the simulation show suggested protocol provided better security compared to the regular blockchain.展开更多
目的建立人促红素注射液(recombinant human erythropoietin,rhEPO)合理性评价体系,分析目前临床使用过程中存在的问题,为临床合理用药提供参考。方法以rhEPO的说明书为基础,参考相关专家共识和指南制定用药合理性评价标准。根据纳入标...目的建立人促红素注射液(recombinant human erythropoietin,rhEPO)合理性评价体系,分析目前临床使用过程中存在的问题,为临床合理用药提供参考。方法以rhEPO的说明书为基础,参考相关专家共识和指南制定用药合理性评价标准。根据纳入标准以及排除标准随机抽取亳州市人民医院2023年4月至2024年4月使用rhEPO的归档病历,应用属性层次模型(attribute hierarchical model,AHM)法对其进行合理性评价,并与传统处方点评方法进行一致性检验,确定AHM法的可行性。结果372份病历中,病历评分(medical record score,MRS)≥90分156例(占41.94%),75分≤MRS<90分55例(占14.78%),60分≤MRS<75分60例(占16.13%),MRS<60分101例(占27.15%);不合理类型主要表现为适应证54例次(占14.52%),用药或停药时机151例次(占40.59%),用药剂量179例次(占48.12%),用药调整163例次(占43.82%)等。与传统处方点评方法比较,AHM法一致率为90.59%(Kappa=0.785,P<0.001)。结论基于AHM法建立的rhEPO评价体系切实可行,评价结果显示,该院rhEPO使用存在不合理现象,医院需在适应证、用药或停药时机、用药剂量及用药调整等方面进一步规范、合理使用。展开更多
The immutability is a crucial property for blockchain applications,however,it also leads to problems such as the inability to revise illegal data on the blockchain and delete private data.Although redactable blockchai...The immutability is a crucial property for blockchain applications,however,it also leads to problems such as the inability to revise illegal data on the blockchain and delete private data.Although redactable blockchains enable on-chain modification,they suffer from inefficiency and excessive centralization,the majority of redactable blockchain schemes ignore the difficult problems of traceability and consistency check.In this paper,we present a Dynamically Redactable Blockchain based on decentralized Chameleon hash(DRBC).Specifically,we propose an Identity-Based Decentralized Chameleon Hash(IDCH)and a Version-Based Transaction structure(VT)to realize the traceability of transaction modifications in a decentralized environment.Then,we propose an efficient block consistency check protocol based on the Bloom filter tree,which can realize the consistency check of transactions with extremely low time and space cost.Security analysis and experiment results demonstrate the reliability of DRBC and its significant advantages in a decentralized environment.展开更多
基金supported by the Natural Science Foundation of Hunan Province(2018JJ2282)
文摘Reliability enhancement testing(RET) is an accelerated testing which hastens the performance degradation process to surface its inherent defects of design and manufacture. It is an important hypothesis that the degradation mechanism of the RET is the same as the one of the normal stress condition. In order to check the consistency of two mechanisms, we conduct two enhancement tests with a missile servo system as an object of the study, and preprocess two sets of test data to establish the accelerated degradation models regarding the temperature change rate that is assumed to be the main applied stress of the servo system during the natural storage. Based on the accelerated degradation models and natural storage profile of the servo system, we provide and demonstrate a procedure to check the consistency of two mechanisms by checking the correlation and difference of two sets of degradation data. The results indicate that the two degradation mechanisms are significantly consistent with each other.
基金supported by research fund of Chungnam National University.
文摘Blockchain is a technology that provides security features that can be used for more than just cryptocurrencies.Blockchain achieves security by saving the information of one block in the next block.Changing the information of one block will require changes to all the next block in order for that change to take effect.Which makes it unfeasible for such an attack to happen.However,the structure of how blockchain works makes the last block always vulnerable for attacks,given that its information is not saved yet in any block.This allows malicious node to change the information of the last block and generate a new block and broadcast it to the network.Given that the nodes always follow the longer chain wins rule,the malicious node will win given that it has the longest chain in the network.This paper suggests a solution to this issue by making the nodes send consistency check messages before broadcasting a block.If the nodes manage to successfully verify that the node that generated a new block hasn’t tampered with the blockchain than that block will be broadcasted.The results of the simulation show suggested protocol provided better security compared to the regular blockchain.
文摘目的建立人促红素注射液(recombinant human erythropoietin,rhEPO)合理性评价体系,分析目前临床使用过程中存在的问题,为临床合理用药提供参考。方法以rhEPO的说明书为基础,参考相关专家共识和指南制定用药合理性评价标准。根据纳入标准以及排除标准随机抽取亳州市人民医院2023年4月至2024年4月使用rhEPO的归档病历,应用属性层次模型(attribute hierarchical model,AHM)法对其进行合理性评价,并与传统处方点评方法进行一致性检验,确定AHM法的可行性。结果372份病历中,病历评分(medical record score,MRS)≥90分156例(占41.94%),75分≤MRS<90分55例(占14.78%),60分≤MRS<75分60例(占16.13%),MRS<60分101例(占27.15%);不合理类型主要表现为适应证54例次(占14.52%),用药或停药时机151例次(占40.59%),用药剂量179例次(占48.12%),用药调整163例次(占43.82%)等。与传统处方点评方法比较,AHM法一致率为90.59%(Kappa=0.785,P<0.001)。结论基于AHM法建立的rhEPO评价体系切实可行,评价结果显示,该院rhEPO使用存在不合理现象,医院需在适应证、用药或停药时机、用药剂量及用药调整等方面进一步规范、合理使用。
基金supported in part by the National Key R&D Program of China under project 2022YFB2702901the Guangxi Natural Science Foundation under grants 2024GXNSFDA010064 and 2024GXNSFAA010453+5 种基金the National Natural Science Foundation of China under projects 62172119,62362013,U21A20467 and 72192801Zhejiang Provincial Natural Science Foundation of China under grant LZ23F020012Innovation Project of GUET Graduate Education under grants 2023YCXS070the Guangxi Young Teachers'Basic Ability Improvement Program under grant 2024KY0224Lion Rock Labs of Cyberspace Security under grant LRL24-1-C003one of the research outcomes of the Xiong'an Autonomous and Controllable Blockchain Underlying Technology Platform Project(2020).
文摘The immutability is a crucial property for blockchain applications,however,it also leads to problems such as the inability to revise illegal data on the blockchain and delete private data.Although redactable blockchains enable on-chain modification,they suffer from inefficiency and excessive centralization,the majority of redactable blockchain schemes ignore the difficult problems of traceability and consistency check.In this paper,we present a Dynamically Redactable Blockchain based on decentralized Chameleon hash(DRBC).Specifically,we propose an Identity-Based Decentralized Chameleon Hash(IDCH)and a Version-Based Transaction structure(VT)to realize the traceability of transaction modifications in a decentralized environment.Then,we propose an efficient block consistency check protocol based on the Bloom filter tree,which can realize the consistency check of transactions with extremely low time and space cost.Security analysis and experiment results demonstrate the reliability of DRBC and its significant advantages in a decentralized environment.
