Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.展开更多
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive...During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.展开更多
The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and wate...The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and water sectors within a basin. With the precondition of strictly controlling maximum emissions rights, initial water rights were allocated between the first and the second levels of the hierarchy in order to promote fair and coordinated development across different regions of the basin and coordinated and efficient water use across different water sectors, realize the maximum comprehensive benefits to the basin, promote the unity of quantity and quality of initial water rights allocation, and eliminate water conflict across different regions and water sectors. According to interactive decision-making theory, a principal-subordinate hierarchical interactive iterative algorithm based on the satisfaction degree was developed and used to solve the initial water rights allocation model. A case study verified the validity of the model.展开更多
An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain varia...An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain variables in real-world problems.Therefore, research on the uncertain multi-objective programming problem is highly relevant, particularly those problems whose objective functions are correlated. In this paper, an approach that solves an uncertain multi-objective programming problem under the expected-variance value criterion is proposed. First, we define the basic framework of the approach and review concepts such as a Pareto efficient solution and expected-variance value criterion using an order relation between various uncertain variables.Second, the uncertain multi-objective problem is converted into an uncertain single-objective programming problem via a linear weighted method or ideal point method. Then the problem is transformed into a deterministic single objective programming problem under the expected-variance value criterion. Third, four lemmas and two theorems are proved to illustrate that the optimal solution of the deterministic single-objective programming problem is an efficient solution to the original uncertainty problem. Finally, two numerical examples are presented to validate the effectiveness of the proposed approach.展开更多
To overcome the defects that the traditional ap-proach for multi-objective programming under uncertain ran-dom environment(URMOP)neglects the randomness and uncer-tainty of the problem and the volatility of the result...To overcome the defects that the traditional ap-proach for multi-objective programming under uncertain ran-dom environment(URMOP)neglects the randomness and uncer-tainty of the problem and the volatility of the results,a new ap-proach is proposed based on expected value-standard devi-ation value criterion(C_(ESD) criterion).Firstly,the effective solution to the URMOP problem is defined;then,by applying sequence relationship between the uncertain random variables,the UR-MOP problem is transformed into a single-objective program-ming(SOP)under uncertain random environment(URSOP),which are transformed into a deterministic counterpart based on the C_(ESD) criterion.Then the validity of the new approach is proved that the optimal solution to the SOP problem is also effi-cient for the URMOP problem;finally,a numerical example and a case application are presented to show the effectiveness of the new approach.展开更多
Adjusting and optimizing land use structure is one of the essential approaches to solve the conflict between land supply and demand. In this study,an uncertain interval multi-objective linear programming model was est...Adjusting and optimizing land use structure is one of the essential approaches to solve the conflict between land supply and demand. In this study,an uncertain interval multi-objective linear programming model was established and applied to analyzing the suitability of land use structure in Pi County of Sichuan Province. An adjustment scheme for optimizing land use structure was proposed on the basis of development planning drawn up by the local government. The results are summarized as follows: 1) the optimal adjustment scope for cropland area ranges from 27 976.75 ha to 31 029.08 ha,and the current area is less than the lower limit of the scope; 2) the optimal adjustment scope for garden land area ranges from 4 736.49 ha to 12 967.11 ha,and the current area is less than the lower limit; 3) the optimal adjustment scope for construction land ranges from 7 761.95 ha to 10 393.18 ha,and the current area is greater than the upper limit; 4) the optimal adjustment scope for industry and mining land ranges from 557.29 ha to 693.54 ha,and the current area exceeds the upper limit; and 5) the areas of forest land,grassland and other agricultural land are within the optimal adjustment scope. In order to maximize comprehensive benefit with the limited resources and the demand of sustainable development,the areas of cropland and garden land are supposed to be expanded properly,while the construction land should be controlled and reduced gradually,and the forest land and other agricultural land can be maintained at the current level in short period.展开更多
Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c...Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.展开更多
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functio...The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.展开更多
Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequent...Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time.展开更多
To improve the efficiency of gate reassignment and optimize the plan of gate reassignment,the concept of disruption management is introduced,and a multi-objective programming model for airport gate reassignment is pro...To improve the efficiency of gate reassignment and optimize the plan of gate reassignment,the concept of disruption management is introduced,and a multi-objective programming model for airport gate reassignment is proposed.Considering the interests of passengers and the airport,the model minimizes the total flight delay,the total passengers′walking distance and the number of flights reassigned to other gates different from the planned ones.According to the characteristics of the gate reassignment,the model is simplified.As the multi-objective programming model is hard to reach the optimal solutions simultaneously,a threshold of satisfactory solutions of the model is set.Then a simulated annealing algorithm is designed for the model.Case studies show that the model decreases the total flight delay to the satisfactory solutions,and minimizes the total passengers′walking distance.The least change of planned assignment is also reached.The results achieve the goals of disruption management.Therefore,the model is verified to be effective.展开更多
According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy m...According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy mathematics. Based on calculation of basic parameters for tl1e formation of production, near-tem optimum models of tropical crops structure of each region was established by means of multi-objective programming, and a far-term grey programming model was set up through the above-mentioned near-term model and prediction of future parameters. Conclusion shows that the near-term programming may raise the profit by 5. 1-55.7 percent and far-tem programming by 54-90 percent, both gainingobvious economic benefits.展开更多
This paper estimates the macroeconornic costs of CO2 emission reduction in China employing the input-output analysis with the multi-objective programming approach. The results show that the effect of reducing CO2 emis...This paper estimates the macroeconornic costs of CO2 emission reduction in China employing the input-output analysis with the multi-objective programming approach. The results show that the effect of reducing CO2 emissions on China＇s economy is significant. Under the present conditions, the estimated macroeconomic costs of CO2 emission reduction in 2010 for China are approximately 3,100-4,024 RMB t-1. The stronger the abatement actions, the higher the macroeconomic costs of per unit emission reduction would be. Excavation industry, oil industry, chemical industry, and metal smelting industry have high potential to abate their CO2 emissions.展开更多
In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are establish...In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are established under this kind of generalized convex functions. Our results generalize the ones obtained by Preda[J Math Anal Appl, 288（2003） 365-382].展开更多
In this paper,a multi-objective sustainable biomass supply chain network under uncertainty is designed by neutrosophic programming method.In this method,for each objective function of the problem,three functions of tr...In this paper,a multi-objective sustainable biomass supply chain network under uncertainty is designed by neutrosophic programming method.In this method,for each objective function of the problem,three functions of truth membership,non-determination and falsehood are considered.Neutrosophic programming method in this paper simultaneously seeks to optimize the total costs of the supply chain network,the amount of greenhouse gas emissions,the number of potential people hired and the time of product transfer along the supply chain network.To achieve the stated objective functions,strategic decisions such as locating potential facilities and tactical decisions such as optimal product flow allocation and vehicle routing must be made.The results of the implementation of neutrosophic programming method show the high efficiency of this method in achieving the optimal values of each objective function.Also,by examining the rate of uncertainty,it was observed that with increasing this rate,the total costs of supply chain network design,greenhouse gas emissions and product transfer times have increased,and in contrast,the potential employment rate of individuals has decreased.展开更多
This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digiti...This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.展开更多
With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply ...With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm.展开更多
This paper presents the Pareto solutions in continuous multi-objective mathematical programming. We discuss the role of some assumptions on the objective functions and feasible domain, the relationship between them, a...This paper presents the Pareto solutions in continuous multi-objective mathematical programming. We discuss the role of some assumptions on the objective functions and feasible domain, the relationship between them, and compactness, contractibility and fixed point properties of the Pareto sets. The authors have tried to remove the concavity assumptions on the objective functions which are usually used in multi-objective maximization problems. The results are based on constructing a retraction from the feasible domain onto the Pareto-optimal set.展开更多
Based on “One Belt and One Road”, this paper studies the path selection of multimodal transport by using the method of multi-objective mixed integer programming. Therefore, this paper studies the factors of transpor...Based on “One Belt and One Road”, this paper studies the path selection of multimodal transport by using the method of multi-objective mixed integer programming. Therefore, this paper studies the factors of transportation time, transportation cost and transportation safety performance, and establishes a mathematical model. In addition, the method of multi-objective mixed integer programming is used to comprehensively consider the different emphasis and differences of customers on cargo transportation. Then we use planning tools of Microsoft Excel to solve path selection and to determine whether the chosen path is economical and reliable. Finally, a relatively complex road network is built as an example to verify the accuracy of this planning method.展开更多
In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient...In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient solution to the MOLFP problem, this modified method provides multiple efficient solutions to the problem. As a result, it provides the decision makers flexibility to choose a better option from alternatives according to their financial position and their level of satisfaction of objectives. A numerical example is provided to illustrate the modified method and also a real life oriented production problem is modeled and solved.展开更多
Computing-in-memory(CIM)has been a promising candidate for artificial-intelligent applications thanks to the absence of data transfer between computation and storage blocks.Resistive random access memory(RRAM)based CI...Computing-in-memory(CIM)has been a promising candidate for artificial-intelligent applications thanks to the absence of data transfer between computation and storage blocks.Resistive random access memory(RRAM)based CIM has the advantage of high computing density,non-volatility as well as high energy efficiency.However,previous CIM research has predominantly focused on realizing high energy efficiency and high area efficiency for inference,while little attention has been devoted to addressing the challenges of on-chip programming speed,power consumption,and accuracy.In this paper,a fabri-cated 28 nm 576K RRAM-based CIM macro featuring optimized on-chip programming schemes is proposed to address the issues mentioned above.Different strategies of mapping weights to RRAM arrays are compared,and a novel direct-current ADC design is designed for both programming and inference stages.Utilizing the optimized hybrid programming scheme,4.67×programming speed,0.15×power saving and 4.31×compact weight distribution are realized.Besides,this macro achieves a normalized area efficiency of 2.82 TOPS/mm2 and a normalized energy efficiency of 35.6 TOPS/W.展开更多
基金financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMFin Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS+2 种基金a predoctoral scholarship from Fundación Universidad Francisco de Vitoriafinancial support from a 6-month contract from Universidad Autónoma de Madrida 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。
文摘Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.
基金supported by the National Natural Sci‐ence Foundation of China(Grant No.62306325)。
文摘During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.
基金supported by the Public Welfare Industry Special Fund Project of the Ministry of Water Resources of China (Grant No. 200701028)the Humanities and Social Science Foundation Program of Hohai University (Grant No. 2008421411)
文摘The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and water sectors within a basin. With the precondition of strictly controlling maximum emissions rights, initial water rights were allocated between the first and the second levels of the hierarchy in order to promote fair and coordinated development across different regions of the basin and coordinated and efficient water use across different water sectors, realize the maximum comprehensive benefits to the basin, promote the unity of quantity and quality of initial water rights allocation, and eliminate water conflict across different regions and water sectors. According to interactive decision-making theory, a principal-subordinate hierarchical interactive iterative algorithm based on the satisfaction degree was developed and used to solve the initial water rights allocation model. A case study verified the validity of the model.
基金supported by the National Natural Science Foundation of China(71601183 71571190)
文摘An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain variables in real-world problems.Therefore, research on the uncertain multi-objective programming problem is highly relevant, particularly those problems whose objective functions are correlated. In this paper, an approach that solves an uncertain multi-objective programming problem under the expected-variance value criterion is proposed. First, we define the basic framework of the approach and review concepts such as a Pareto efficient solution and expected-variance value criterion using an order relation between various uncertain variables.Second, the uncertain multi-objective problem is converted into an uncertain single-objective programming problem via a linear weighted method or ideal point method. Then the problem is transformed into a deterministic single objective programming problem under the expected-variance value criterion. Third, four lemmas and two theorems are proved to illustrate that the optimal solution of the deterministic single-objective programming problem is an efficient solution to the original uncertainty problem. Finally, two numerical examples are presented to validate the effectiveness of the proposed approach.
基金supported by the National Natural Science Foundation of China(72001213)the basic research program of Natural Science of Shaanxi Province,China(2021JQ-369).
文摘To overcome the defects that the traditional ap-proach for multi-objective programming under uncertain ran-dom environment(URMOP)neglects the randomness and uncer-tainty of the problem and the volatility of the results,a new ap-proach is proposed based on expected value-standard devi-ation value criterion(C_(ESD) criterion).Firstly,the effective solution to the URMOP problem is defined;then,by applying sequence relationship between the uncertain random variables,the UR-MOP problem is transformed into a single-objective program-ming(SOP)under uncertain random environment(URSOP),which are transformed into a deterministic counterpart based on the C_(ESD) criterion.Then the validity of the new approach is proved that the optimal solution to the SOP problem is also effi-cient for the URMOP problem;finally,a numerical example and a case application are presented to show the effectiveness of the new approach.
基金Under the auspices of National Key Technology R&D Program of China (No. 2006BAB04A08)
文摘Adjusting and optimizing land use structure is one of the essential approaches to solve the conflict between land supply and demand. In this study,an uncertain interval multi-objective linear programming model was established and applied to analyzing the suitability of land use structure in Pi County of Sichuan Province. An adjustment scheme for optimizing land use structure was proposed on the basis of development planning drawn up by the local government. The results are summarized as follows: 1) the optimal adjustment scope for cropland area ranges from 27 976.75 ha to 31 029.08 ha,and the current area is less than the lower limit of the scope; 2) the optimal adjustment scope for garden land area ranges from 4 736.49 ha to 12 967.11 ha,and the current area is less than the lower limit; 3) the optimal adjustment scope for construction land ranges from 7 761.95 ha to 10 393.18 ha,and the current area is greater than the upper limit; 4) the optimal adjustment scope for industry and mining land ranges from 557.29 ha to 693.54 ha,and the current area exceeds the upper limit; and 5) the areas of forest land,grassland and other agricultural land are within the optimal adjustment scope. In order to maximize comprehensive benefit with the limited resources and the demand of sustainable development,the areas of cropland and garden land are supposed to be expanded properly,while the construction land should be controlled and reduced gradually,and the forest land and other agricultural land can be maintained at the current level in short period.
基金supported by Canada First Research Excellence Fund,Medicine by Design(to CMM)。
文摘Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.
基金supported by National Institute on Aging(NIH-NIA)R21 AG074152(to KMA)National Institute of Allergy and Infectious Diseases(NIAID)grant DP2 AI171150(to KMA)Department of Defense(DoD)grant AZ210089(to KMA)。
文摘The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.
基金supported by the National Natural Science Foundation of China(No.62203256)。
文摘Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time.
基金Supported by the National Natural Science Foundation of China(71103034)the Natural Science Foundation of Jiangsu Province(bk2011084)
文摘To improve the efficiency of gate reassignment and optimize the plan of gate reassignment,the concept of disruption management is introduced,and a multi-objective programming model for airport gate reassignment is proposed.Considering the interests of passengers and the airport,the model minimizes the total flight delay,the total passengers′walking distance and the number of flights reassigned to other gates different from the planned ones.According to the characteristics of the gate reassignment,the model is simplified.As the multi-objective programming model is hard to reach the optimal solutions simultaneously,a threshold of satisfactory solutions of the model is set.Then a simulated annealing algorithm is designed for the model.Case studies show that the model decreases the total flight delay to the satisfactory solutions,and minimizes the total passengers′walking distance.The least change of planned assignment is also reached.The results achieve the goals of disruption management.Therefore,the model is verified to be effective.
文摘According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy mathematics. Based on calculation of basic parameters for tl1e formation of production, near-tem optimum models of tropical crops structure of each region was established by means of multi-objective programming, and a far-term grey programming model was set up through the above-mentioned near-term model and prediction of future parameters. Conclusion shows that the near-term programming may raise the profit by 5. 1-55.7 percent and far-tem programming by 54-90 percent, both gainingobvious economic benefits.
基金supported by the National Natural Science Foundation of China under Grant Nos. 70825001 and 70941039
文摘This paper estimates the macroeconornic costs of CO2 emission reduction in China employing the input-output analysis with the multi-objective programming approach. The results show that the effect of reducing CO2 emissions on China＇s economy is significant. Under the present conditions, the estimated macroeconomic costs of CO2 emission reduction in 2010 for China are approximately 3,100-4,024 RMB t-1. The stronger the abatement actions, the higher the macroeconomic costs of per unit emission reduction would be. Excavation industry, oil industry, chemical industry, and metal smelting industry have high potential to abate their CO2 emissions.
基金Foundation item： Supported by Hunan Provincial Natural Science Foundation of China（05JJ40103） Supported by Soft Science Research Fund of Hunan Province（2006ZK3028） Supported by Scientific Research Fund of Hunan Provincial Education Department（105B0707, 08C470）
文摘In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are established under this kind of generalized convex functions. Our results generalize the ones obtained by Preda[J Math Anal Appl, 288（2003） 365-382].
文摘In this paper,a multi-objective sustainable biomass supply chain network under uncertainty is designed by neutrosophic programming method.In this method,for each objective function of the problem,three functions of truth membership,non-determination and falsehood are considered.Neutrosophic programming method in this paper simultaneously seeks to optimize the total costs of the supply chain network,the amount of greenhouse gas emissions,the number of potential people hired and the time of product transfer along the supply chain network.To achieve the stated objective functions,strategic decisions such as locating potential facilities and tactical decisions such as optimal product flow allocation and vehicle routing must be made.The results of the implementation of neutrosophic programming method show the high efficiency of this method in achieving the optimal values of each objective function.Also,by examining the rate of uncertainty,it was observed that with increasing this rate,the total costs of supply chain network design,greenhouse gas emissions and product transfer times have increased,and in contrast,the potential employment rate of individuals has decreased.
文摘This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.
基金Education and Teaching Research Project of Beijing University of Technology(ER2024KCB08)。
文摘With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm.
文摘This paper presents the Pareto solutions in continuous multi-objective mathematical programming. We discuss the role of some assumptions on the objective functions and feasible domain, the relationship between them, and compactness, contractibility and fixed point properties of the Pareto sets. The authors have tried to remove the concavity assumptions on the objective functions which are usually used in multi-objective maximization problems. The results are based on constructing a retraction from the feasible domain onto the Pareto-optimal set.
文摘Based on “One Belt and One Road”, this paper studies the path selection of multimodal transport by using the method of multi-objective mixed integer programming. Therefore, this paper studies the factors of transportation time, transportation cost and transportation safety performance, and establishes a mathematical model. In addition, the method of multi-objective mixed integer programming is used to comprehensively consider the different emphasis and differences of customers on cargo transportation. Then we use planning tools of Microsoft Excel to solve path selection and to determine whether the chosen path is economical and reliable. Finally, a relatively complex road network is built as an example to verify the accuracy of this planning method.
文摘In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient solution to the MOLFP problem, this modified method provides multiple efficient solutions to the problem. As a result, it provides the decision makers flexibility to choose a better option from alternatives according to their financial position and their level of satisfaction of objectives. A numerical example is provided to illustrate the modified method and also a real life oriented production problem is modeled and solved.
基金supported in part by the National Natural Science Foundation of China (62422405, 62025111,62495100, 92464302)the STI 2030-Major Projects(2021ZD0201200)+1 种基金the Shanghai Municipal Science and Technology Major Projectthe Beijing Advanced Innovation Center for Integrated Circuits
文摘Computing-in-memory(CIM)has been a promising candidate for artificial-intelligent applications thanks to the absence of data transfer between computation and storage blocks.Resistive random access memory(RRAM)based CIM has the advantage of high computing density,non-volatility as well as high energy efficiency.However,previous CIM research has predominantly focused on realizing high energy efficiency and high area efficiency for inference,while little attention has been devoted to addressing the challenges of on-chip programming speed,power consumption,and accuracy.In this paper,a fabri-cated 28 nm 576K RRAM-based CIM macro featuring optimized on-chip programming schemes is proposed to address the issues mentioned above.Different strategies of mapping weights to RRAM arrays are compared,and a novel direct-current ADC design is designed for both programming and inference stages.Utilizing the optimized hybrid programming scheme,4.67×programming speed,0.15×power saving and 4.31×compact weight distribution are realized.Besides,this macro achieves a normalized area efficiency of 2.82 TOPS/mm2 and a normalized energy efficiency of 35.6 TOPS/W.
