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Balancing switching and transient response for ion gating in field-effect nanofluidic transistors
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作者 Xiaoqing Wu Yajie Chen +3 位作者 Dagui Wang Song Pu Qiujiao Du Pengcheng Gao 《Chinese Chemical Letters》 2026年第1期385-388,共4页
Field-effect nanofluidic transistors(FENTs),biomimicking the structure and functionality of neuron,act as biological transistors with the ability to gate switching responses to external stimuli.The switching ratio has... Field-effect nanofluidic transistors(FENTs),biomimicking the structure and functionality of neuron,act as biological transistors with the ability to gate switching responses to external stimuli.The switching ratio has been verified to evaluate the performance of FENTs,but until recently,the response time,another crucial indicator,has been ignored.Employing finite-element method,we investigated the relationship among gate charge,switching ratio and response time by divisionally manipulating gate charge,including entrance surface and the surface of confinement space,for ion transport to optimize switching capability.The dual-split gate charge on FENTs exhibits synergistic effect on switching response.Based on the two regional gate charge on FENTs,multivalence ions in lower concentration,high aspect ratio and single channel show higher switching ratio but longer response time compared to monovalent ions.The findings highlight the necessity of balancing these two signals in FENTs and offer insights for optimizing their design and expanding applications to dual-signal-detection iontronics. 展开更多
关键词 Nanofluidic transistor Gate charge Ion transport switching ratio Response time
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A Multi-Gap Multi-Channel Gas Switch for the Linear Transformer Driver 被引量:3
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作者 刘轩东 梁天学 +4 位作者 孙凤举 姜晓峰 李佳 孙福 邱爱慈 《Plasma Science and Technology》 SCIE EI CAS CSCD 2009年第6期725-729,共5页
A multi-gap and multi-channel gas switch with convexo-convex discal planet electrodes was designed and investigated. Eight gaps are formed in series by a trigger electrode, six intermediate electrodes and two high vol... A multi-gap and multi-channel gas switch with convexo-convex discal planet electrodes was designed and investigated. Eight gaps are formed in series by a trigger electrode, six intermediate electrodes and two high voltage electrodes with a uniform gap length of 5 ram. The self breakdown and triggered breakdown performance of the switch are reported. Both the delay time and jitter decrease with the increase in the trigger voltage, switching coefficient and the decrease in the trigger isolating resistor. The delay time of the switch is about 40 ns, and the jitter is less than 2 ns when charged with 4-85 kV and triggered by a voltage pule of -75 kV. The inductance of the switch is about 30 nH. 展开更多
关键词 multi-gap multi-channel gas spark closing switch linear transformer driver delay time JITTER
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Optical Diagnostics of Multi-Gap Gas Switches for Linear Transformer Drivers 被引量:1
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作者 盛亮 李阳 +7 位作者 孙铁平 丛培天 张美 彭博栋 赵吉祯 岳志勤 魏福利 袁媛 《Plasma Science and Technology》 SCIE EI CAS CSCD 2014年第7期677-682,共6页
The trigger characteristics of a multi-gap gas switch with double insulating layers,a square-groove electrode supporter and a UV pre-ionizing structure are investigated aided by a high sensitivity fiber-bundle array d... The trigger characteristics of a multi-gap gas switch with double insulating layers,a square-groove electrode supporter and a UV pre-ionizing structure are investigated aided by a high sensitivity fiber-bundle array detector, a UV fiber detector, and a framing camera, in addition to standard electrical diagnostics. The fiber-bundle-array detector is used to track the turn-on sequence of each electrode gap at a timing precision of 0.6 ns. Each fiber bundle, including five fibers with different azimuth angles, aims at the whole emitting area of each electrode gap and is fed to a photomultiplier tube. The UV fiber detector with a spectrum response of 260-320 nm,including a fused-quartz fiber of 200 μm in diameter and a solar-blinded photomultiplier tube, is adopted to study the effect of UV pre-ionizing on trigger characteristics. The framing camera,with a capacity of 4 frames per shot and an exposure time of 5 ns, is employed to capture the evolution of channel arcs. Based on the turn-on light signal of each electrode gap, the breakdown delay is divided into statistical delay and formative delay. A decrease in both of them, a smaller switch jitter and more channel arcs are observed with lower gas pressure. An increase in trigger voltage can reduce the statistical delay and its jitter, while higher trigger voltage has a relatively small influence on the formative delay and the number of channel arcs. With the UV pre-ionizing structure at 0.24 MPa gas pressure and 60 kV trigger voltage, the statistical delay and its jitter can be reduced by 1.8 ns and 0.67 ns, while the formative delay and its jitter can only be reduced by 0.5 ns and 0.25 ns. 展开更多
关键词 optical diagnostics multi-gap gas switches linear transformer driver
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Experimental Study of the Multi-gap Multi-channel Gas Spark Closing Switch 被引量:2
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作者 孙凤举 曾江涛 +3 位作者 邱爱慈 张嘉生 尹佳辉 邱毓昌 《Plasma Science and Technology》 SCIE EI CAS CSCD 2001年第4期871-876,共6页
A coaxial multi-gap multi-channel spark switch with stainless-steel-spring ring gap electrodes is designed and investigated. The switch is triggered by a pulse applied to the cylindrical electrode outside the discharg... A coaxial multi-gap multi-channel spark switch with stainless-steel-spring ring gap electrodes is designed and investigated. The switch is triggered by a pulse applied to the cylindrical electrode outside the discharging channel through a parasitic capacitance coupling. The jitter of the switch is reduced by several short-distance gas gaps in series, and its inductance is reduced by a multi-channel discharge on account of the inductance isolation between the coils of the spring ring electrode. The experimental results indicate that the switch is of low inductance (15-30 nH), low jitter (-3 ns), and stable breakdown performance 展开更多
关键词 Experimental Study of the multi-gap Multi-channel Gas Spark Closing switch MMCS
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基于UVM的PCIe交换芯片Switch子系统验证平台的设计 被引量:1
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作者 郑锐 沈剑良 +2 位作者 刘冬培 李智超 曹睿 《计算机应用研究》 北大核心 2025年第5期1480-1489,共10页
PCIe是一种高速串行计算机扩展总线标准,据此设计的PCIe交换芯片可将CPU提供的PCIe通道扩展出更多的PCIe接口。然而,随着PCIe交换芯片设计复杂度和验证向量剧增,传统基于Verilog搭建的验证平台难以实现对逻辑复杂的Switch子系统高效地验... PCIe是一种高速串行计算机扩展总线标准,据此设计的PCIe交换芯片可将CPU提供的PCIe通道扩展出更多的PCIe接口。然而,随着PCIe交换芯片设计复杂度和验证向量剧增,传统基于Verilog搭建的验证平台难以实现对逻辑复杂的Switch子系统高效地验证,且缺乏功能覆盖率模型。为解决上述问题,采用UVM通用验证方法学,搭建了针对PCIe交换芯片中Switch子系统的验证平台,采用层次划分设计,支持覆盖率驱动,且较于一般UVM验证平台作出效率优化。具体而言,首先,对平台组件Reference Model建立通信对象和通信方式进行优化设计;其次,对平台组件ScoreBoard的比对方式和接收报文端口进行改进;最后,依据PCIe协议及交换芯片特点,对功能点进行梳理分类后针对性地设计了测试用例,对Switch子系统进行全面验证。经信号波形及覆盖率数据的分析表明,改进后的验证平台在没有人为过滤的情况下实现了96.8%的代码覆盖率和100%的功能覆盖率,仿真时间平均减少了约10%。该平台显著提升了验证效率,高效地支撑了PCIe交换芯片的验证工作,为相关UVM验证平台的搭建提供了参考。 展开更多
关键词 PCIe交换芯片 switch子系统 UVM验证平台 reference model ScoreBoard 覆盖率
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Primary Investigation into the Laser Triggering Multi-Gap Multi-Channel Gas Switch in a Single Test Module Facility 被引量:8
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作者 何安 李丰平 +5 位作者 邓建军 杨向东 李洪涛 丰树平 顾元朝 谢卫平 《Plasma Science and Technology》 SCIE EI CAS CSCD 2006年第5期602-606,共5页
A high precision laser trigger system is built up in the single test module of Primary Test Stand (PTS) facility. A fourth harmonic, with a wavelength A of 266 nm, Q-switched Nd:YAG laser was used to trigger the 5 ... A high precision laser trigger system is built up in the single test module of Primary Test Stand (PTS) facility. A fourth harmonic, with a wavelength A of 266 nm, Q-switched Nd:YAG laser was used to trigger the 5 MV multi-gap multi-channel gas switch which was filled with high pressure SF6-N2 mixture gas. The maximum deviation and the standard deviation in the jitter time of the trigger system is 4- 0.7 ns and 0.3 ns respectively. The maximum deviation and the standard deviation in the jitter time for the multi-gap multi-channel laser triggering switch is 4- 2.4 ns and 1.5 ns respectively. The curve of switch delay-time versus laser energy is obtained, which is helpful for the choice of fitting laser energy. The successful test with two lasers indicated that the design of using twenty-four lasers to trigger twenty-four switches respectively is feasible in "PTS". 展开更多
关键词 TRIGGER Q-switched Nd:YAG laser PTS JITTER electromagnetic interference
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Electropolymerized dopamine-based memristors using threshold switching behaviors for artificial current-activated spiking neurons 被引量:1
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作者 Bowen Zhong Xiaokun Qin +4 位作者 Zhexin Li Yiqiang Zheng Lingchen Liu Zheng Lou Lili Wang 《Journal of Semiconductors》 2025年第2期98-103,共6页
Memristors have a synapse-like two-terminal structure and electrical properties,which are widely used in the construc-tion of artificial synapses.However,compared to inorganic materials,organic materials are rarely us... Memristors have a synapse-like two-terminal structure and electrical properties,which are widely used in the construc-tion of artificial synapses.However,compared to inorganic materials,organic materials are rarely used for artificial spiking synapses due to their relatively poor memrisitve performance.Here,for the first time,we present an organic memristor based on an electropolymerized dopamine-based memristive layer.This polydopamine-based memristor demonstrates the improve-ments in key performance,including a low threshold voltage of 0.3 V,a thin thickness of 16 nm,and a high parasitic capaci-tance of about 1μF·mm^(-2).By leveraging these properties in combination with its stable threshold switching behavior,we con-struct a capacitor-free and low-power artificial spiking neuron capable of outputting the oscillation voltage,whose spiking fre-quency increases with the increase of current stimulation analogous to a biological neuron.The experimental results indicate that our artificial spiking neuron holds potential for applications in neuromorphic computing and systems. 展开更多
关键词 ELECTROPOLYMERIZATION POLYDOPAMINE MEMRISTOR threshold switching spiking voltage artificial neuron
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High-performance triboelectric nanogenerator based on a rotating-switch structure for efficient wind energy harvesting 被引量:1
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作者 Juan Pan Wuliang Sun +5 位作者 Ying Zhan Xiaoxia Lv Xin Li Yaxin Huang Baodong Chen Ding Nan 《Energy Materials and Devices》 2025年第2期72-82,71,共12页
Existing nanogenerator technologies for harvesting high-power energy from wind encounter significant chal-lenges due to limitations in current output.Here,we propose a rotating-switch triboelectric nanogenerator(RS-TE... Existing nanogenerator technologies for harvesting high-power energy from wind encounter significant chal-lenges due to limitations in current output.Here,we propose a rotating-switch triboelectric nanogenerator(RS-TENG)that uses mechanical triggering switches(on-off-on)to enhance the instantaneous current pulses during rotation.The rotating-switch in the proposed device addresses the issue of low instantaneous current output in triboelectric nanogenerators while maintaining voltage stability.At a constant rotational speed,the RS-TENG achieves an instantaneous current of 3.2 times that of its nonswitching counterpart,with an 89%reduction in response time.Furthermore,at a wind speed of 2 m·s^(-1),the RS-TENG achieves a wind power density of 10.4 mW·m^(-2)·m^(-1)·s.Additionally,by integrating the RS-TENG with energy management circuits,the nanogenerator can power wireless signal transmitters and temperature sensors,offering a self-sustaining power solution for remote wireless services.This research presents a promising technology for powering electronic devices in energy-scarce environments. 展开更多
关键词 triboelectric nanogenerator rotating switches instantaneous current generation power density self-powered sensing systems
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A Comprehensive Review of Torque and Speed Control Strategies for Switched Reluctance Motor Drives 被引量:1
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作者 Sreeram K Preetha P K +1 位作者 Javier Rodríguez-García Carlosálvarez-Bel 《CES Transactions on Electrical Machines and Systems》 2025年第1期46-75,共30页
Switched Reluctance Motors(SRMs),outfitted with rugged construction,good speed range,high torque density,and rare earth-free nature that outweigh induction motors(IM)and permanent magnet synchronous motor(PMSM),afford... Switched Reluctance Motors(SRMs),outfitted with rugged construction,good speed range,high torque density,and rare earth-free nature that outweigh induction motors(IM)and permanent magnet synchronous motor(PMSM),afford a broad range of applications in the domain of electric vehicles(EVs).Standard copper magnetic wire and low-carbon steel laminations are used to construct SRMs,which give them high efficiency in the range of 85-95%.Despite SRM's desirable features over traditional motor-speed drives,high torque ripples and radial distortions constrain their deployment in EVs.Precise rotor position is imperative for effective management of the speed and torque of SRMs.This paper provides an illustrative compendium on review of the torque-speed control and ripple mitigation techniques using design enhancements and control methods for SRM drives for EV applications.The various schemes were evaluated on their performance metricsoperational speed range,control complexity,practical realization,need for pre-stored parameters(look-up tables of current,inductance and torque profiles)and motor controller memory requirements.The findings provide valuable insights into balancing the gains and trade-offs associated with EV applications.Furthermore,they pinpoint opportunities for enhancement by analyzing the cost and technical aspects of different SRM controllers. 展开更多
关键词 Electric vehicles switched reluctance motor Speed control Torque control Traction motor Torque ripple
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Smooth switching mechanism-based adaptive integral terminal SMC for PMSM servo system with stator voltage saturation and unknown disturbances 被引量:1
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作者 Xiangxiang Meng Haisheng Yu +1 位作者 Jie Zhang Qing Yang 《Control Theory and Technology》 2025年第2期294-309,共16页
This article investigates the anti-disturbance and stabilization problems for the nonlinear uncertain permanent magnet synchronous motor(PMSM)with stator voltage saturation and unknown load.A smooth switching mechanis... This article investigates the anti-disturbance and stabilization problems for the nonlinear uncertain permanent magnet synchronous motor(PMSM)with stator voltage saturation and unknown load.A smooth switching mechanism is presented to structure the adaptive integral terminal sliding mode control(SMC)strategy.The control design consists of compensation control and nominal control,which improves the rapidity and accuracy of trajectory tracking.The smooth saturation model based on the error function is applied to approximate the voltage saturation phenomenon.Additionally,to deal with the adverse effects of various unknown disturbances,including model parameter uncertainties and unknown external load disturbances,an improved disturbance observer(DO)is proposed.This observer effectively suppresses the fluctuations caused by fixed gain during the starting period of the system.Finally,the experimental results under different conditions show that the proposed strategy has good tracking and disturbance suppression performances. 展开更多
关键词 Smooth switching mechanism Integral terminal SMC PMSM servo system Disturbance suppression Stator voltage saturation
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SIRT3-PINK1-PKM2 axis prevents osteoarthritis via mitochondrial renewal and metabolic switch 被引量:1
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作者 Yaoge Deng Mingzhuang Hou +7 位作者 Yubin Wu Yang Liu Xiaowei Xia Chenqi Yu Jianfeng Yu Huilin Yang Yijian Zhang Xuesong Zhu 《Bone Research》 2025年第3期686-701,共16页
Maintaining mitochondrial homeostasis is critical for preserving chondrocyte physiological conditions and increasing resistance against osteoarthritis(OA).However,the underlying mechanisms governing mitochondrial self... Maintaining mitochondrial homeostasis is critical for preserving chondrocyte physiological conditions and increasing resistance against osteoarthritis(OA).However,the underlying mechanisms governing mitochondrial self-renewal and energy production remain elusive.In this study,we demonstrated mitochondrial damage and aberrant mitophagy in OA chondrocytes.Genetically overexpressing PTEN-induced putative kinase 1(PINK1)protects against cartilage degeneration by removing defective mitochondria.PINK1 knockout aggravated cartilage damage due to impaired mitophagy.SIRT3 directly deacetylated PINK1 to promote mitophagy and cartilage anabolism.Specifically,PINK1 phosphorylated PKM2 at the Ser127 site,preserving its active tetrameric form.This inhibited nuclear translocation and the interaction withβ-catenin,resulting in a metabolic shift and increased energy production.Finally,a double-knockout mouse model demonstrated the role of the SIRT3-PINK1-PKM2 axis in safeguarding the structural integrity of articular joints and improving motor functions.Overall,this study provides a novel insight into the regulation of mitochondrial renewal and metabolic switches in OA. 展开更多
关键词 aberrant mitophagy mitochondrial renewal maintaining mitochondrial homeostasis mitochondrial damage cartilage degeneration SIRT removing defective mitochondriapink metabolic switch
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Grid-Connected/Islanded Switching Control Strategy for Photovoltaic Storage Hybrid Inverters Based on Modified Chimpanzee Optimization Algorithm
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作者 Chao Zhou Narisu Wang +1 位作者 Fuyin Ni Wenchao Zhang 《Energy Engineering》 EI 2025年第1期265-284,共20页
Uneven power distribution,transient voltage,and frequency deviations are observed in the photovoltaic storage hybrid inverter during the switching between grid-connected and island modes.In response to these issues,th... Uneven power distribution,transient voltage,and frequency deviations are observed in the photovoltaic storage hybrid inverter during the switching between grid-connected and island modes.In response to these issues,this paper proposes a grid-connected/island switching control strategy for photovoltaic storage hybrid inverters based on the modified chimpanzee optimization algorithm.The proposed strategy incorporates coupling compensation and power differentiation elements based on the traditional droop control.Then,it combines the angular frequency and voltage amplitude adjustments provided by the phase-locked loop-free pre-synchronization control strategy.Precise pre-synchronization is achieved by regulating the virtual current to zero and aligning the photovoltaic storage hybrid inverter with the grid voltage.Additionally,two novel operators,learning and emotional behaviors are introduced to enhance the optimization precision of the chimpanzee algorithm.These operators ensure high-precision and high-reliability optimization of the droop control parameters for photovoltaic storage hybrid inverters.A Simulink model was constructed for simulation analysis,which validated the optimized control strategy’s ability to evenly distribute power under load transients.This strategy effectively mitigated transient voltage and current surges during mode transitions.Consequently,seamless and efficient switching between gridconnected and island modes was achieved for the photovoltaic storage hybrid inverter.The enhanced energy utilization efficiency,in turn,offers robust technical support for grid stability. 展开更多
关键词 Photovoltaic storage hybrid inverters modified chimpanzee optimization algorithm droop control seamless switching
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Finite-Time Stability of Impulsive and Switched Hybrid Systems With Delay-Dependent Impulses
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作者 Taixiang Zhang Jinde Cao +1 位作者 Mahmoud Abdel-Aty Ardak Kashkynbayev 《IEEE/CAA Journal of Automatica Sinica》 2025年第2期466-468,共3页
Dear Editor,This letter studies finite-time stability (FTS) of impulsive and switched hybrid systems with delay-dependent impulses. Some conditions, based on Lyapunov method, are proposed for ensuring FTS and estimati... Dear Editor,This letter studies finite-time stability (FTS) of impulsive and switched hybrid systems with delay-dependent impulses. Some conditions, based on Lyapunov method, are proposed for ensuring FTS and estimating settling-time function (STF) of the hybrid systems.When switching dynamics are FTS and impulsive dynamics involve destabilizing delay-dependent impulses, the FTS is retained if the impulses occur infrequently. 展开更多
关键词 finite time stability delay dependent impulses hybrid systemswhen switching dynamics impulsive dynamics impulsive switched hybrid systems switched systems lyapunov method
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Enantiomeric organic amine-borane adduct crystals with room-temperature multi-channel switches
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作者 Zi-Yi Yu Gen-Feng Li +4 位作者 Zhe-Kun Xu Lipeng Long Yan Qin Zi-Yi Du Zhong-Xia Wang 《Chinese Journal of Structural Chemistry》 2025年第11期46-52,共7页
Stimuli-responsive materials offer significant potential for high-security encryption,smart sensors,and optoelectronic switching due to their reversible state transitions triggered by external stimuli(temperature,ligh... Stimuli-responsive materials offer significant potential for high-security encryption,smart sensors,and optoelectronic switching due to their reversible state transitions triggered by external stimuli(temperature,light,or electric fields).Combining quasi-spherical molecular design with chiral engineering,we designed enantiomeric organic amine-borane adduct crystals exhibiting multi-channel switching behavior at room temperature.The strategic introduction of intramolecular hydrogen bonding and chirality in engineered R/S-HQNB crystals successfully enables room-temperature structural phase transitions.This transition is coupled with pronounced onoff switching in dielectric,SHG,and SHG-CD responses,demonstrating practical application potential through ambient-temperature operation,which is rarely documented in pure small molecule organic crystals.This advance establishes a pathway for functional organic materials design and enables chiral optical applications with integrated stimuli-responsive capabilities. 展开更多
关键词 Enantiomeric amine-borane adduct Structural phase transition Dielectric switching SHG switching SHG-CD
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Nanosecond pulse and dual-wavelength Q-switched 1.5 μm fiber laser using MAX phase Cr_(2)TiAlC_(2) saturable absorber
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作者 Ahmed Shakir AL-HITI Hiba HASSAN 《Optoelectronics Letters》 2025年第1期7-12,共6页
We demonstrated a new type of MAX phase material,chromium titanium aluminum carbide(Cr_(2)TiAlC_(2)) polymer film,to generate a passively Q-switched erbium-doped fiber laser(EDFL).The film thickness was measured to be... We demonstrated a new type of MAX phase material,chromium titanium aluminum carbide(Cr_(2)TiAlC_(2)) polymer film,to generate a passively Q-switched erbium-doped fiber laser(EDFL).The film thickness was measured to be around 45 μm,which was fabricated using the embedding method with polyvinyl alcohol(PVA) polymer as hoster.The saturable absorber(SA) film demonstrates a dual-wavelength passively Q-switched EDFL which operates at 1 531 nm and 1 560.19 nm,respectively.The Q-switching pulse duration could be varied from 2.46 μs to 770 ns,while the repetition rate varied from 92.76 kHz to 106.6 kHz with an increasing input pumping range from 154 mW to 300 mW.The maximum output power and pulse energy of 15.05 mW and 141.18 nJ were obtained at the maximum input power of 300 mW,respectively. 展开更多
关键词 switchED pulse fiber
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Time-Varying Formation Tracking Control of Heterogeneous Multi-Agent Systems With Intermittent Communications and Directed Switching Networks
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作者 Yuhan Wang Zhuping Wang +1 位作者 Hao Zhang Huaicheng Yan 《IEEE/CAA Journal of Automatica Sinica》 2025年第1期294-296,共3页
Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present so... Dear Editor,This letter is concerned with the problem of time-varying formation tracking for heterogeneous multi-agent systems(MASs) under directed switching networks. For this purpose, our first step is to present some sufficient conditions for the exponential stability of a particular category of switched systems. 展开更多
关键词 switched systems time varying formation tracking directed switching networks heterogeneous multi agent systems intermittent communications exponential stability
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Dual-responsive Flexible Dielectric Switching Composites for Overheating Warning and Small Deformation Monitoring
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作者 Chuan-Yu Jiang Hai-Rong Li +6 位作者 Yu Peng Liu-Yang Zhang Wu-Hou Fan Luo-Xin Wang Ming Jiang Zi-Qing Cai Li-Jie Dong 《Chinese Journal of Polymer Science》 2025年第10期1885-1893,共9页
The phenomena of thermal runaway and accidental deformation due to external stresses in lithium batteries or film capacitors consti-tute their primary failure mechanisms.Therefore,monitoring and early warning of overh... The phenomena of thermal runaway and accidental deformation due to external stresses in lithium batteries or film capacitors consti-tute their primary failure mechanisms.Therefore,monitoring and early warning of overheating or localized strain are of great value for the safe use of lithium batteries or film capacitors;however,this function usually requires a system of multiple complex sensors.The realization of the above multiple hazards using a single sensor for monitoring and alarm functions has not been reported.Here,we exploit the thermally induced conductivity and modulus change during solid-liquid conversion of low melting point polyalloys to modulate the electronic relaxation polariza-tion and interfacial polarization in the composites for dielectric switching,and the reduction of alloy particle spacing during bending/compres-sive strain can be used to generate switchable tunneling effects for insulator-conductor transition.By synergizing dielectric switching and insula-tor-conductor transition,the final flexible thermoplastic polyurethane elastomer/low-melting-point polyalloy composite film achieves the func-tional integration of multi-level overheating warning and small deformation monitoring. 展开更多
关键词 Dielectric switching Insulator-conductor transition Polarization OVERHEATING DEFORMATION
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SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy
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作者 Qianhui Ling Xilan Dong +5 位作者 Liyan Mao Chengjun Huang Linjing Cong Haizeng Zhang Jun Cai Zhenzhen Chen 《Animal Models and Experimental Medicine》 2025年第8期1400-1415,共16页
Background : SOX6 has been shown to play a crucial role in the development of the cardiovascular system. However, its potential role in hypertension and vascular function remains unclear. Methods : In vascular smooth ... Background : SOX6 has been shown to play a crucial role in the development of the cardiovascular system. However, its potential role in hypertension and vascular function remains unclear. Methods : In vascular smooth muscle cells(VSMCs), we employed gain-and loss-offunction approaches combined with RNA sequencing, autophagy flux assessment, and phenotype characterization. Additionally, we established a mouse model with Sox6 overexpression via adeno-associated virus 2(AAV2) to validate the findings in vivo. Results : We validated the increased expression of SOX6 in hypertension both in vitro and in vivo. Genetic silencing of Sox6 in VSMCs attenuated the phenotypic switching induced by angiotensin Ⅱ. Conversely, in vivo overexpression of Sox6 led to a significant elevation in blood pressure and promoted vascular remodeling. Mechanistically, SOX6 was shown to regulate phenotypic switching via an autophagydependent pathway. Specifically, Sox6 overexpression augmented VSMC autophagy and facilitated phenotypic switching, whereas Sox6 knockdown yielded opposite outcomes. Modulation of autophagy using 3-MA or RAPA could effectively counteract the effect mediated by SOX6. Conclusions : Our findings revealed that SOX6 regulates VSMC plasticity and elevates blood pressure by activating autophagy. Therefore, SOX6 inhibition potentially represents a novel strategy for treating hypertension and vascular remodeling. 展开更多
关键词 AUTOPHAGY HYPERTENSION SOX6 VSMC phenotypic switching
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Research on adaptive smooth switching control strategy for strong and weak power grids in multi-machine parallel PV energy storage VSG system
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作者 Zuobin Zhu Shumin Sun Yueming Ding 《Global Energy Interconnection》 2025年第5期790-803,共14页
To enable distributed PV to adapt to variations in power grid strength and achieve stable grid connection while enhancing operational flexibility,it is essential to configure grid-connected inverters with an integrate... To enable distributed PV to adapt to variations in power grid strength and achieve stable grid connection while enhancing operational flexibility,it is essential to configure grid-connected inverters with an integrated grid-following control mode,allowing smooth switching between GFL and GFM modes.First,impedance models of GFL and GFM PV energy storage VSG systems were established,and grid stability was analyzed.Second,an online impedance identification method based on voltage fluctuation data screening was proposed to enhance the accuracy of impedance identification.Additionally,a PV energy storage GFM/GFL VSG smooth switching method based on current inner loop compensation was introduced to achieve stable grid-connected operation of distributed photovoltaics under changes in strong and weak power grids.Finally,a grid stability analysis was conducted on the multi-machine parallel PV ESS,and a simulation model of a multi-machine parallel PV ESS based on current inner loop compensation was established for testing.Results showed that,compared to using a single GFM or single GFL control for the PV VSG system,the smooth switching method of multi-machine parallel PV ESS effectively suppresses system resonance under variations in power grid strength,enabling adaptive and stable grid-connected operations of distributed PV. 展开更多
关键词 PV GFM VSG GFL VSG RESONANCE Smooth switching
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Global Terminal Switching Sliding Mode Control of Robot Manipulators Based on Entire Fixed-Time Disturbance Observer
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作者 Fengning Zhang 《Journal of Electronic Research and Application》 2025年第3期294-302,共9页
This paper presents an entire fixed-time disturbance observer-based global terminal switching sliding mode control of robot manipulators,which has inner and external uncertainties.The entire fixed-time disturbance obs... This paper presents an entire fixed-time disturbance observer-based global terminal switching sliding mode control of robot manipulators,which has inner and external uncertainties.The entire fixed-time disturbance observer-based global terminal switching sliding mode control has the global finite-time reaching characteristic,the property that system convergence time can be prescribed,and the global robustness to uncertainties,with the entire fixed-time disturbance observer that accurately estimates uncertainties after a fixed time,despite the initial state.The joints of the control system can arrive at the prescribed joint angular position at the predefined joint angular speed at the prescribed time. 展开更多
关键词 Prescribed-time stability Sliding mode switched control
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