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Analysis and Discussion on the Current Situation of Medical Imaging Quality Control and Quality
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作者 He Liming Zhang Fang +2 位作者 Xu Yandong Du Hai Huo Yanhong 《Science International Innovative Medicine》 2025年第4期1-5,共5页
This study aims to analyze and discuss the current situation of quality control and quality management in medical imaging.Firstly,it defines the concepts of quality management and image quality,emphasizing the crucial... This study aims to analyze and discuss the current situation of quality control and quality management in medical imaging.Firstly,it defines the concepts of quality management and image quality,emphasizing the crucial role of the department's Quality and Safety Team in imaging quality management[1].Subsequently,it details the composition and responsibilities of the Quality and Safety Management Group,as well as the specific divisions of labor and tasks of the Quality Management Team.The effective implementation of comprehensive quality control in the imaging department is ensured through the"Seven-Star Sword"method,which encompasses total process control,organization-wide participation,and total quality control[2].Furthermore,the application of the PDCA(Plan-Do-Check-Act)cycle in quality management is explored,along with strategies to improve patient satisfaction by reducing the waiting time for imaging reports[3].Finally,the management of a key departmental medical quality control indicator—critical values—is analyzed,and improvement measures are proposed[4].This study underscores the importance of quality management in enhancing medical service quality and ensuring patient safety,and puts forward specific implementation strategies and improvement methods. 展开更多
关键词 Medical imaging Quality control Quality Management PDCA Critical Value Management
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Controlled illumination and seismic acquisition geometry for target-oriented imaging 被引量:5
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作者 刘守伟 耿建华 冯伟 《Applied Geophysics》 SCIE CSCD 2005年第4期230-234,共5页
The conventional method of seismic data acquisition geometry design is based on the assumption of horizontal subsurface reflectors, which often is not suitable for complex structure. We start from a controlled illumin... The conventional method of seismic data acquisition geometry design is based on the assumption of horizontal subsurface reflectors, which often is not suitable for complex structure. We start from a controlled illumination analysis and put forward a method of seismic survey geometry design for target-oriented imaging. The method needs a velocity model obtained by a preliminary seismic interpretation. The one-way Fourier finite-difference wave propagator is used to extrapolate plane wave sources on the target layer to the surface. By analyzing the wave energy distribution at the surface extrapolated from the target layer, the shot or receiver locations needed for target layer imaging can be determined. Numerical tests using the SEG-EAGE salt model suggest that this method is useful for confirming the special seismic acquisition geometry layout for target-oriented imaging. 展开更多
关键词 seismic acquisition geometry controlled illumination target-oriented imaging.
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Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies 被引量:4
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作者 Maythem Saeed Steven W Hetts +1 位作者 Robert Jablonowski Mark W Wilson 《World Journal of Cardiology》 CAS 2014年第11期1192-1208,共17页
Myocardial pathologies are major causes of morbidity and mortality worldwide. Early detection of loss of cellular integrity and expansion in extracellular volume(ECV) in myocardium is critical to initiate effective tr... Myocardial pathologies are major causes of morbidity and mortality worldwide. Early detection of loss of cellular integrity and expansion in extracellular volume(ECV) in myocardium is critical to initiate effective treatment. The three compartments in healthy myocardium are: intravascular(approximately 10% of tissue volume), interstitium(approximately 15%) and intracellular(approximately 75%). Myocardial cells, fibroblasts and vascular endothelial/smooth muscle cells represent intracellular compartment and the main proteins in the interstitium are types Ⅰ/Ⅲ collagens. Microscopic studies have shown that expansion of ECV is an important feature of diffuse physiologic fibrosis(e.g., aging and obesity) and pathologic fibrosis [heart failure, aortic valve disease, hypertrophic cardiomyopathy, myocarditis, dilated cardiomyopathy, amyloidosis, congenital heart disease, aortic stenosis, restrictive cardiomyopathy(hypereosinophilic and idiopathic types), arrythmogenic right ventricular dysplasia and hypertension]. This review addresses recent advances in measuring of ECV in ischemic and non-ischemic myocardial pathologies. Magnetic resonance imaging(MRI) has the ability to characterize tissue proton relaxation times(T1, T2, and T2*). Proton relaxation times reflect the physical and chemical environments of water protons in myocardium. Delayed contrast enhanced-MRI(DE-MRI) and multi-detector computed tomography(DE-MDCT) demonstrated hyper-enhanced infarct, hypo-enhanced microvascular obstruction zone and moderately enhanced peri-infarct zone, but are limited for visualizing diffuse fibrosis and patchy microinfarct despite the increase in ECV. ECV can be measured on equilibrium contrast enhanced MRI/MDCT and MRI longitudinal relaxation time mapping. Equilibrium contrast enhanced MRI/MDCT and MRI T1 mapping is currently used, but at a lower scale, as an alternative to invasive sub-endomyocardial biopsies to eliminate the need for anesthesia, coronary catheterization and possibility of tissue sampling error. Similar to delayed contrast enhancement, equilibrium contrast enhanced MRI/MDCT and T1 mapping is completely noninvasive and may play a specialized role in diagnosis of subclinical and other myocardial pathologies. DE-MRI and when T1-mapping demonstrated sub-epicardium, sub-endocardial and patchy mid-myocardial enhancement in myocarditis, Behcet's disease and sarcoidosis, respectively. Furthermore, recent studies showed that the combined technique of cine, T2-weighted and DE-MRI technique has high diagnostic accuracy for detecting myocarditis. When the tomographic techniques are coupled with myocardial perfusion and left ventricular function they can provide valuable information on the progression of myocardial pathologies and effectiveness of new therapies. 展开更多
关键词 Myocardial viability Ischemic/non-ischemic heart diseases Magnetic resonance imaging multi-detector computed tomography Cellular compartments Contrast media
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Off-axis multi-wavelength dispersion controllingmetalens for multi-color imaging 被引量:19
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作者 Kaihua Dou Xin Xie +4 位作者 Mingbo Pu Xiong Li Xiaoliang Ma Changtao Wang Xiangang Luo 《Opto-Electronic Advances》 2020年第4期7-13,共7页
Dispersion control is crucial in optical systems,and chromatic aberration is an important factor affecting imaging quality in imaging systems.Due to the inherent property of materials,dispersion engineering is complex... Dispersion control is crucial in optical systems,and chromatic aberration is an important factor affecting imaging quality in imaging systems.Due to the inherent property of materials,dispersion engineering is complex and needs to trade off other aberration in traditional ways.Although metasurface offers an effective method to overcome these limits and results in well-engineered dispersion,off-axis dispersion control is still a challenging topic.In this paper,we design a single-layer metalens which is capable of focusing at three wavelengths(473 nm,532 nm,and 632 nm)with different incident angles(0°,-17°and 17°)into the same point.We also demonstrate that this metalens can provide an alternative for the bulky color synthetic prism in a 3-chips digital micromirror device(DMD)laser projection system.Through this approach,various off-axis dispersion controlling optical devices could be realized. 展开更多
关键词 OFF-AXIS DISPERSION control metalens COLOR imaging
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Recent advancement of chemical imaging in pharmaceutical quality control:From final product testing to industrial utilization 被引量:3
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作者 Luming Liu Haibin Qu 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2020年第1期19-34,共16页
Chemical imaging(CI)possesses a strong ability of pharmaceutical analysis.Its great strength relies on the integration of traditional spectroscopy(one dimension)and imaging technique(two dimensions)to generate three-d... Chemical imaging(CI)possesses a strong ability of pharmaceutical analysis.Its great strength relies on the integration of traditional spectroscopy(one dimension)and imaging technique(two dimensions)to generate three-dimensional data hypercubes.Data pre-processing or processing methods are proposed to analyze vast data matrixes and thereby realizing different research objectives.In this review paper,various pharmaceutical applications of quality control over the past few years are summed up in two groups of final product test and industrial utilization.The scope of"quality control"here includes traditional analytical use,process understanding and manufactural control.Finally,two major challenges about undesirable sample geometry and lengthy acquisition time are discussed for prospective commercial or industrial application. 展开更多
关键词 Hyperspectral imaging pharmaceutical application multivariate data analysis quality control
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A Controlled Study on Comparing Differences in CT Perfusion Imaging between Rabbits inoculated with VX2 Lung Tumor and Patients with Squamous Cell Carcinoma of the Lung 被引量:3
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作者 Qiang ZHANG Qi-bao SHI Zhao-xin LIU Ming-min ZHANG 《Clinical Oncology and Cancer Research》 CAS CSCD 2010年第6期366-372,共7页
OBJECTIVE By analysis and evaluation of the perfusion images and perfusion parameters of the rabbits with VX2 lung tumor, the association between the perfusion parameters and tumor angiogenesis of patients with squamo... OBJECTIVE By analysis and evaluation of the perfusion images and perfusion parameters of the rabbits with VX2 lung tumor, the association between the perfusion parameters and tumor angiogenesis of patients with squamous cell carcinoma of the lung has been studied in order to establish a non-invasive and effective way to detect tumor blood supply, which is be able to exhibit hemodynamic data in tumors during cancer treatments. METHODS Fifteen Netherlands rabbits inoculated with VX2 lung tumor (rabbit group) and 25 patients with squamous cell carcinoma of the lung (patient group) received a multi-slice spiral CT perfusion imaging test using the Netherlands PHILIPS Brilliance 16-slice spiral CT and a U.S. MEDRAD binocular highpressure syringe. Image postprocessing was done using the special perfusion software and EBW 4.0 Workstation. Perfusion volume (PV), peak enhanced increment (PEI), transit time peak (TTP), and blood volume (BV) were measured and analyzed. RESULTS In the rabbit group, the values of the PV, PEI, TTP, and BV of the tumor margin were (53.89 ± 13.38) mL/(min.mL), (45.71 ± 15.52) Hu, (39.29 ± 10.10) sec, and (31.45 ± 18.19) mL/100 g, respectively; these values of the tumor center were (36.57 ± 14.17) mL/(min.mL), (28.64 ± 11.74) Hu, (39.00 + 9.78) sec, and (19.76 ± 13.95) mL/100 g, respectively; the values of the muscles were (12.45± 4.38) mL/(min.mL), (10.98 ± 5.03) Hu, (38.86 ± 10.04) sec, and (5.38 ±2.87) mL/100 g, respectively. The values of the relative perfusion volume (RPV), relative peak enhanced increment (RPEI), and relative blood volume (RBV) of the tumor margin were 4.38 ± 1.45, 3.96± 1.45, 9.99 ± 11.7, respectively; these values of the tumor center were 2.14 ± 1.08, 1.83±1.45, 4.17 ±3.39, respectively. The values of the PV, PEL BV of the tumor margin vs. the values of the muscles developed t-values, which were 15.028, 10.79, and 5.88, respectively (P ≤ 0.01), with statistical significance; the values of the PV, PEI, BV of the tumor center vs. the values of the muscles produced t-values, which were 8.67, 7.49, and 4.55, respectively (P 〈 0.01), with statistical significance. The values of the TTP of the tumor margin vs. TTP values of the muscles, and the TTP values of the tumor center vs. TTP values of the muscles developed t-values, which were 1.7 and 0.806, respectively (P ≥ 0.05), without statistical significance. In the patient group, the values of the PV, PE, TTP, and BV of the tumor margin were (88.95 ± 30.89) mL/(min.mL), (61.87 ± 27.31) Hu, (37.72 ± 12.53) sec, and (18.38 ± 7.2) mL/100 g, respectively; these values of the tumor center were (39.77 ± 18.29) mL/(min.mL), (14.57 ± 8.1) Hu, (35.64 ± 12.41) sec, and (11.22 ± 6.02) mL/100 g, respectively; these values of the muscles were (12.45 ± 6.5) mL/(min.mL), (6.14 ± 2.66) Hu, (35.68± 12.35) sec, and (2.23 ± 1.11) mL/100 g, respectively. The values of the RPV, RPEI, and RBV of the tumor margin were 8.05 ± 5.04, 8.87 ± 4.32, and 12.16 ± 8.49, respectively; these values of the tumor center were 2.39 ± 1.68, 2.97 ± 2.1, 3.53 ± 2.82, respectively. The values of the PV, PEI, BV of the tumor margin in the patient group vs. the values of the muscles produced t-values, which were 13.8, 10.85, and 12.22, respectively (P 〈 0.01), with significant differences; these values of the tumor center vs. the values of the muscles developed t-values, which were 9.158, 6.26, 8.654, respectively (P 〈 0.01), with significant differences. The TTP value of the tumor margin vs. that of the muscles produced t-value, which was 0.371, and the TTP value of the tumor center vs. that of the muscles developed t-value, which was 1 (P 〉 0.05), without statistical difference. CONCLUSION CT perfusion imaging technics demonstrates directly dynamic changes of blood flow to tumors, which assists in identifying tumor growth and necrosis, therefore, this research provides an evidence-based guidelines for the treatment of human lung squamous cell carcinoma and has far-reaching clinical significance. 展开更多
关键词 perfusion imaging lung neoplasms controlled study.
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Multicenter randomised controlled trial comparing the high definition white light endoscopy and the bright narrow band imaging for colon polyps 被引量:2
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作者 Rajvinder Singh Kuan Loong Cheong +10 位作者 Leonardo Zorron Cheng Tao Pu Dileep Mangira Doreen Siew Ching Koay Carmen Kee Siew Chien Ng Rungsun Rerknimitr Satimai Aniwan Tiing-Leong Ang Khean-Lee Goh Shiaw Hooi Ho James Yun-Wong Lau 《World Journal of Gastrointestinal Endoscopy》 CAS 2017年第6期273-281,共9页
AIM To compare high definition white light endoscopy and bright narrow band imaging for colon polyps' detection rates. METHODS Patients were randomised to high definition white light endoscopy(HD-WLE) or the brigh... AIM To compare high definition white light endoscopy and bright narrow band imaging for colon polyps' detection rates. METHODS Patients were randomised to high definition white light endoscopy(HD-WLE) or the bright narrow band imaging(b NBI) during withdrawal of the colonoscope. Polyps identified in either mode were characterised using b NBI with dual focus(b NBI-DF) according to the Sano's classification. The primary outcome was to compare adenoma detection rates(ADRs) between the two arms. The secondary outcome was to assess the negative predictive value(NPV) in differentiating adenomas from hyperplastic polyps for diminutive rectosigmoid lesions.RESULTS A total of 1006 patients were randomised to HD-WLE(n = 511) or b NBI(n = 495). The mean of adenoma per patient was 1.62 and 1.84, respectively. The ADRs in b NBI and HD-WLE group were 37.4% and 39.3%, respectively. When adjusted for withdrawal time(OR = 1.19, 95%CI: 1.15-1.24, P < 0.001), the use of b NBI was associated with a reduced ADR(OR = 0.69, 95%CI: 0.52-0.92). Nine hundred and thirty three polyps(86%) in both arms were predicted with high confidence. The sensitivity(Sn), specificity(Sp), positive predictive value and NPV in differentiating adenomatous from non-adenomatous polyps of all sizes were 95.9%, 87.2%, 94.0% and 91.1% respectively. The NPV in differentiating an adenoma from hyperplastic polyp using b NBI-DF for diminutive rectal polyps was 91.0%.CONCLUSION ADRs did not differ between b NBI and HD-WLE, however HD-WLE had higher ADR after adjustment of withdrawal time. b NBI surpassed the PIVI threshold for diminutive polyps. 展开更多
关键词 Narrow band imaging Dual focus High definition White light endoscopy COLON POLYPS Randomised controlled trial
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Magnetic imaging-assisted colonoscopy vs conventional colonoscopy: A randomized controlled trial 被引量:1
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作者 Christopher W Teshima Sergio Zepeda-Gómez +1 位作者 Suliman H AlShankiti Gurpal S Sandha 《World Journal of Gastroenterology》 SCIE CAS 2014年第36期13178-13184,共7页
AIM: To compare magnetic imaging-assisted colonoscopy (MIC) with conventional colonoscopy (CC).
关键词 COLONOSCOPY Conscious sedation Magnetic endoscope imaging Pain measurement Randomized controlled trial
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Randomised controlled trial comparing modified Sano's and narrow band imaging international colorectal endoscopic classifications for colorectal lesions 被引量:4
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作者 Leonardo Zorrón Cheng Tao Pu Kuan Loong Cheong +7 位作者 Doreen Siew Ching Koay Sze Pheh Yeap Amanda Ovenden Mahima Raju Andrew Ruszkiewicz Philip W Chiu James Y Lau Rajvinder Singh 《World Journal of Gastrointestinal Endoscopy》 2018年第9期210-218,共9页
AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between... AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between 2013 and 2015 were enrolled in this trial.Based on the MS or the NICE classifications,patients were randomised for real-time endoscopic diagnosis.This was followed by biopsies,endoscopic or surgical resection.The endoscopic diagnosis was then compared to the final(blinded) histopathology.The primary endpoint was the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of differentiating neoplastic and non-neoplastic polyps(MSⅡ/Ⅱo/Ⅲa/Ⅲb vs I or NICE 1 vs 2/3).The secondary endpoints were "endoscopic resectability"(MSⅡ/Ⅱo/Ⅲa vs Ⅰ/Ⅲb or NICE 2 vs 1/3),NPV for diminutive distal adenomas and prediction of post-polypectomy surveillance intervals.RESULTS A total of 348 patients were evaluated.The Sn,Sp,PPV and NPV in differentiating neoplastic polyps from non-neoplastic polyps were,98.9%,85.7%,98.2% and 90.9% for MS;and 99.1%,57.7%,95.4% and 88.2% for NICE,respectively.The area under the receiver operating characteristic curve(AUC) for MS was 0.92(95%CI:0.86-0.98);and AUC for NICE was 0.78(95%CI:0.69,0.88).The Sn,Sp,PPV and NPV in predicting "endoscopic resectability" were 98.9%,86.1%,97.8% and 92.5% for MS;and 98.6%,66.7%,94.7% and 88.9% for NICE,respectively.The AUC for MS was 0.92(95%CI:0.87-0.98);and the AUC for NICE was 0.83(95%CI:0.75-0.90).The AUC values were statistically different for both comparisons(P = 0.0165 and P = 0.0420,respectively).The accuracy for diagnosis of sessile serrated adenoma/polyp(SSA/P) with high confidence utilizing MS classification was 93.2%.The differentiation of SSA/P from other lesions achieved Sp,Sn,PPV and NPV of 87.2%,91.5%,89.6% and 98.6%,respectively.The NPV for predicting adenomas in diminutive rectosigmoid polyps(n = 150) was 96.6% and 95% with MS and NICE respectively.The calculated accuracy of post-polypectomy surveillance for MS group was 98.2%(167 out of 170) and for NICE group was 92.1%(139 out of 151).CONCLUSION The MS classification outperformed the NICE classification in differentiating neoplastic polyps and predicting endoscopic resectability.Both classifications met ASGE PIVI thresholds. 展开更多
关键词 COLORECTAL POLYPS COLORECTAL ADENOMAS COLORECTAL NEOPLASM COLORECTAL lesions RANDOMISED controlled trial COLONOSCOPY Magnifying COLONOSCOPY Endoscopic imaging
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Imaging characteristics of brain microstructure and cerebral perfusion in Crohn’s disease patients with anxiety: A prospective comparative study
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作者 Ke-Cen Yue Ying-Yin Zhu +3 位作者 Jing-Wen Sun Xin-Tong Wu Wen-Jia Liu Hai-Feng Shi 《World Journal of Gastroenterology》 2025年第4期72-87,共16页
BACKGROUND Anxiety is a common comorbidity in patients with Crohn’s disease(CD).Data on the imaging characteristics of brain microstructure and cerebral perfusion in CD with anxiety are limited.AIM To compare the ima... BACKGROUND Anxiety is a common comorbidity in patients with Crohn’s disease(CD).Data on the imaging characteristics of brain microstructure and cerebral perfusion in CD with anxiety are limited.AIM To compare the imaging characteristics of brain microstructure and cerebral perfusion among CD patients with or without anxiety and healthy individuals.METHODS This prospective comparative study enrolled consecutive patients with active CD and healthy individuals who visited the study hospital between January 2022 and January 2023.Anxiety was measured using the Hospital Anxiety and Depression Scale-Anxiety.The imaging characteristics of brain microstructure and cerebral perfusion were measured by diffusion kurtosis imaging and intravoxel incoherent motion.RESULTSA total of 57 participants were enrolled. Among the patients with active CD, 16 had anxiety. Compared withhealthy individuals, patients with active CD demonstrated significantly lower radial kurtosis values in the rightcerebellar region 6, lower axial kurtosis (AK) values in the right insula, left superior temporal gyrus, and rightthalamus, and higher slow and fast apparent diffusion coefficients (ADCslow and ADCfast) in the bilateral frontal lobe,bilateral temporal lobe, and bilateral insular lobe (all P < 0.05). Compared with patients with CD without anxiety,patients with CD and anxiety exhibited significantly higher ADCslow values in the left insular lobe and lower AKvalues in the right insula and right anterior cuneus (all P < 0.05).CONCLUSIONThere are variations in brain microstructure and perfusion among CD patients with/without anxiety and healthyindividuals, suggesting potential use in assessing anxiety-related changes in active CD. 展开更多
关键词 Crohn’s disease ANXIETY Diffusion magnetic resonance imaging Brain perfusion Healthy controls Prospective comparative study
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Correlation of liver imaging and transient elastography among patients with hepatitis C at a safety net hospital
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作者 Hima Veeramachaneni Bobak Moazzami +2 位作者 Navila Sharif Emad Qayed Lesley S Miller 《World Journal of Hepatology》 2025年第4期67-74,共8页
BACKGROUND Liver imaging and transient elastography(TE)are both tools used to assess liver fibrosis and steatosis among people with hepatitis C virus(HCV)infection.However,the diagnostic accuracy of conventional imagi... BACKGROUND Liver imaging and transient elastography(TE)are both tools used to assess liver fibrosis and steatosis among people with hepatitis C virus(HCV)infection.However,the diagnostic accuracy of conventional imaging in detecting fibrosis and steatosis in this patient population remains unclear.AIM To investigate the correlation between steatosis and fibrosis and abnormal findings on liver imaging in patients with HCV.METHODS We conducted a retrospective cross-sectional analysis of patients with HCV at Grady Liver Clinic who had TE exams between 2018-2019.We analyzed the correlation of controlled attenuation parameter and liver stiffness measurement on TE and abnormal findings on liver imaging.Liver imaging findings(hepatic steatosis,increased echogenicity,cirrhosis,and chronic liver disease)were further evaluated for their diagnostic performance in detecting fibrosis(≥F2,≥F3,≥F4)and steatosis(≥S1,≥S2,≥S3).RESULTS Of 959 HCV patients who underwent TE,651 had liver imaging.Higher controlled attenuation parameter scores were observed in patients with abnormal liver findings(P=0.0050),hepatic steatosis(P<0.0001),and increased echogenicity(P<0.0001).Higher liver stiffness measurement values were also noted in those with abnormal liver(P<0.0001)and increased echogenicity(P=0.0026).Steatosis severity correlated with hepatic steatosis(r=0.195,P<0.001)and increased echogenicity(r=0.209,P<0.001).For fibrosis detection,abnormal liver imaging had moderate sensitivity(81.7%)and specificity(70.4%)for cirrhosis(≥F4),while cirrhosis on imaging had high specificity(99.2%)but low sensitivity(18.3%).Increased echogenicity showed high specificity(92.8%)but low sensitivity(20.9%)for steatosis detection.CONCLUSION Liver imaging detects advanced fibrosis and steatosis but lacks early-stage sensitivity.Integrating TE with imaging may improve evaluation in patients with HCV. 展开更多
关键词 Transient elastography Liver stiffness measurement controlled attenuation parameter Hepatic steatosis Hepatic fibrosis Liver imaging Chronic hepatitis C virus
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Operation Control of a High-resolution Plasma Imaging System in KT5D Torus
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作者 孙翔 许敏 +9 位作者 余羿 闻一之 俞昌旋 马锦绣 王之江 陆荣华 王俊 朱振华 前川孝 打田 《Plasma Science and Technology》 SCIE EI CAS CSCD 2005年第5期2999-3001,共3页
This paper describes the control software together with the operational hardware, which successfully realizes the operation of a new fully programmable imaging system with high spatial and temporal resolutions on the ... This paper describes the control software together with the operational hardware, which successfully realizes the operation of a new fully programmable imaging system with high spatial and temporal resolutions on the KT5D magnetic torus, for observing the visible l ight emission from the plasma discharge. 展开更多
关键词 magnetically confined plasma high-resolution imaging programmable hard-ware operation control software
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Ultra-thin temperature controllable microwell array chip for continuous real-time high-resolution imaging of living single cells
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作者 Yuanyuan Wu Lei Zhao +3 位作者 Yaran Chang Liang Zhao Guangsheng Guo Xiayan Wang 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第11期3446-3449,共4页
Single-cell imaging,a powerful analytical method to study single-cell behavior,such as gene expression and protein profiling,provides an essential basis for modern medical diagnosis.The coding and localization functio... Single-cell imaging,a powerful analytical method to study single-cell behavior,such as gene expression and protein profiling,provides an essential basis for modern medical diagnosis.The coding and localization function of microfluidic chips has been developed and applied in living single-cell imaging in recent years.Simultaneously,chip-based living single-cell imaging is also limited by complicated trapping steps,low cell utilization,and difficult high-resolution imaging.To solve these problems,an ultra-thin temperature-controllable microwell array chip(UTCMA chip)was designed to develop a living single-cell workstation in this study for continuous on-chip culture and real-time high-resolution imaging of living single cells.The chip-based on ultra-thin ITO glass is highly matched with an inverted microscope(or confocal microscope)with a high magnification objective(100×oil lens),and the temperature of the chip can be controlled by combining it with a home-made temperature control device.High-throughput single-cell patterning is realized in one step when the microwell array on the chip uses hydrophilic glass as the substrate and hydrophobic SU-8 photoresist as the wall.The cell utilization rate,single-cell capture rate,and microwell occupancy rate are all close to 100%in the microwell array.This method will be useful in rare single-cell research,extending its application in the biological and medical-related fields,such as early diagnosis of disease,personalized therapy,and research-based on single-cell analysis. 展开更多
关键词 Ultra-thin microchip Temperature controllable Living single cells One-step patterning Continuous culture High-resolution imaging
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Coronary arterial bypass graft patency evaluated by multi-detector computed tomography and magnetic resonance imaging
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作者 Li Yang 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2007年第4期248-249,共2页
  The progression of atherosclerosis of the coronary artery does not stop after coronary arterial bypass grafting (CABG) surgery.……
关键词 CABG Coronary arterial bypass graft patency evaluated by multi-detector computed tomography and magnetic resonance imaging
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Structural control of magnetic nanoparticles for positive nuclear magnetic resonance imaging
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作者 Zulaikha Ali Yunfei Zhang +5 位作者 Michael GKaul Billy Truong Deepika Bhanot Gerhard Adam Yuan-Yuan Li He Wei 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第10期17-28,共12页
In addition to the tens of millions of medical doses consumed annually around the world,a vast number of nuclear magnetic resonance imaging(MRI)contrast agents are being deployed in MRI research and development,offeri... In addition to the tens of millions of medical doses consumed annually around the world,a vast number of nuclear magnetic resonance imaging(MRI)contrast agents are being deployed in MRI research and development,offering precise diagnostic information,targeting capabilities,and analyte sensing.Superparamagnetic iron oxide nanoparticles(SPIONs)are notable among these agents,providing effective and versatile MRI applications while also being heavy-metal-free,bioconjugatable,and theranostic.We designed and implemented a novel two-pronged computational and experimental strategy to meet the demand for the efficient and rigorous development of SPION-based MRI agents.Our MATLAB-based modeling simulation and magnetic characterization revealed that extremely small maghemite SPIONs in the 1-3 nm range possess significantly reduced transversal relaxation rates(R_(2))and are therefore preferred for positive(T_(1)-weighted)MRI.Moreover,X-ray diffraction and X-ray absorption fine structure analyses demonstrated that the diffraction pattern and radial distribution function of our SPIONs matched those of the targeted maghemite crystals.In addition,simulations of the X-ray near-edge structure spectra indicated that our synthesized SPIONs,even at 1 nm,maintained a spherical structure.Furthermore,in vitro and in vivo MRI investigations showed that our 1-nm SPIONs effectively highlighted whole-body blood vessels and major organs in mice and could be cleared through the kidney route to minimize potential post-imaging side effects.Overall,our innovative approach enabled a swift discovery of the desired SPION structure,followed by targeted synthesis,synchrotron radiation spectroscopic studies,and MRI evaluations.The efficient and rigorous development of our high-performance SPIONs can set the stage for a computational and experimental platform for the development of future MRI agents. 展开更多
关键词 Magnetic nanoparticles Structure control Nuclear magnetic resonance imaging Modeling simulation X-ray absorption fine structure
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Imaging diagnosis of pancreatic cancer:A state-of-the-art review 被引量:26
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作者 Eun Sun Lee Jeong Min Lee 《World Journal of Gastroenterology》 SCIE CAS 2014年第24期7864-7877,共14页
Pancreatic cancer(PC)remains one of the deadliest cancers worldwide,and has a poor,five-year survival rate of 5%.Although complete surgical resection is the only curative therapy for pancreatic cancer,less than20%of n... Pancreatic cancer(PC)remains one of the deadliest cancers worldwide,and has a poor,five-year survival rate of 5%.Although complete surgical resection is the only curative therapy for pancreatic cancer,less than20%of newly-diagnosed patients undergo surgical resection with a curative intent.Due to the lack of early symptoms and the tendency of pancreatic adenocarcinoma to invade adjacent structures or to metastasize at an early stage,many patients with pancreatic cancer already have advanced disease at the time of their diagnosis and,therefore,there is a high mortality rate.To improve the patient survival rate,early detection of PC is critical.The diagnosis of PC relies on computed tomography(CT)and/or magnetic resonance imaging(MRI)with magnetic resonance cholangiopancreatography(MRCP),or biopsy or fine-needle aspiration using endoscopic ultrasound(EUS).Although multi-detector row computed tomography currently has a major role in the evaluation of PC,MRI with MRCP facilitates better detection of tumors at an early stage by allowing a comprehensive analysis of the morphological changes of the pancreas parenchyma and pancreatic duct.The diagnosis could be improved using positron emission tomography techniques in special conditions in which CT and EUS are not completely diagnostic.It is essential for clinicians to understand the advantages and disadvantages of the various pancreatic imaging modalities in order to be able to make optimal treatment and management decisions.Our study investigates the current role and innovative techniques of pancreatic imaging focused on the detection of pancreatic cancer. 展开更多
关键词 Pancreatic neoplasms multi-detector computed tomography Magnetic resonance imaging ULTRASONOGRAPHY Endoscopic ultrasound-guided fine needle aspiration Positron-emission tomography
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Realizing precision pulse TIG welding with arc length control and visual image sensing based weld detection 被引量:5
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作者 孙振国 陈念 陈强 《China Welding》 EI CAS 2003年第1期11-16,共6页
Methods of arc length control and visual image based weld detection for precision pulse TIG welding were investigated. With a particular all hardware circuit, arc voltage during peak current stage is sampled and inte... Methods of arc length control and visual image based weld detection for precision pulse TIG welding were investigated. With a particular all hardware circuit, arc voltage during peak current stage is sampled and integrated to indicate arc length, deviation of arc length and adjusting parameters are calculated and output to drive a step motor directly. According to the features of welding image grabbed with CCD camera, a special algorithm was developed to detect the central line of weld fast and accurately. Then an application system were established, whose static arc length error is ±0.1 mm with 20 A average current and 1 mm given arc length, static detection precision of weld is 0.01 mm , processing time of each image is less than 120 ms . Precision pulse TIG welding of some given thin stainless steel components with complicated curved surface was successfully realized. 展开更多
关键词 pulse TIG welding visual image sensing arc length control weld detection
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Flotation Control System Based on Recognition of Froth Image 被引量:2
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作者 王振翀 路迈西 +1 位作者 陈浚 赵建庆 《International Journal of Mining Science and Technology》 SCIE EI 2000年第2期42-44,共3页
In industrial flotation, froth layer plays an important role and reflects directly whether coal, air, water and reagents match each other properly or not and whether the quality of flotation is good or not. So the sup... In industrial flotation, froth layer plays an important role and reflects directly whether coal, air, water and reagents match each other properly or not and whether the quality of flotation is good or not. So the supervision and recognition of the state of froth layer is very important in the flotation process. The ash content of clean coal froth was predicted through extracting the features of images of flotation froth. The froth images were classified according to their structure. A control system of adding flotation reagents was established based on the LVQ neural net. 展开更多
关键词 froth imagE RECOGNITION control SYSTEM
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Imaging Diagnosis of TypeⅢCholedochal Cyst:A Case Report 被引量:1
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作者 Ping Li Liang Zhu +3 位作者 Xuan Wang Huadan Xue Xin Wu Zhengyu Jin 《Chinese Medical Sciences Journal》 CAS CSCD 2018年第3期194-198,共5页
Choledochocele is a congenital abnormality of the biliary system,which characterized by a cystic dilatation of intramural segment of the distal common bile duct.Choledochocele manifests as cystic lesions in the duoden... Choledochocele is a congenital abnormality of the biliary system,which characterized by a cystic dilatation of intramural segment of the distal common bile duct.Choledochocele manifests as cystic lesions in the duodenal lumen and resembles duodenal duplication cysts in imaging.We reported a patient with choledochocele.Magnetic resonance cholangiopancreatography showed a thin-walled sac in the duodenal cavity and a fine tubular structure connecting with the end of the common bile duct.Magnetic resonance cholangiopancreatography is a noninvasive and convenient technique in the diagnosis of choledochocele. 展开更多
关键词 CHOLEDOCHOCELE gastrointestinal imaging multi-detector computed tomography endoscopic RETROGRADE CHOLANGIOPANCREATOGRAPHY MAGNETIC RESONANCE imaging MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY
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Functional magnetic resonance imaging and diffusion tensor tractography of the corticopontocerebellar tract in the human brain 被引量:1
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作者 Ji Heon Hong Sung Ho Jang 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第1期76-80,共5页
The anatomical organization of the corticopontocerebellar tract (CPCT) in the human brain remains poorly understood. The present study investigated probabilistic tractography of the CPCT in the human brain using dif... The anatomical organization of the corticopontocerebellar tract (CPCT) in the human brain remains poorly understood. The present study investigated probabilistic tractography of the CPCT in the human brain using diffusion tensor tractography with functional magnetic resonance imaging. CPCT data was obtained from 14 healthy subjects. CPCT images were obtained from functional magnetic resonance imaging and diffusion tensor tractography, revealing that the CPCT originated from the primary sensorimotor cortex and descended to the pontine nucleus through the corona radiata, the posterior limb of the internal capsule, and the cerebral peduncle. After crossing the pons through the transverse pontine fibers, the CPCT entered the cerebellum via the middle cerebral peduncle. However, some variation was detected in the midbrain (middle cerebral peduncle and/or medial lemniscus) and pons (ventral and/or dorsal transverse pontine fibers). The CPCT was analyzed in 3 dimensions from the cerebral cortex to the cerebellum. These results could be informative for future studies of motor control in the human brain. 展开更多
关键词 functional magnetic resonance imaging diffusion tensor image corticopontocerebellar tract: motor control ataxia
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